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Sequences

Sequence NM_197961

AACGAACCGGAAGTGCTAAAGCCTCCGAGGCCAAGGCCGCTGCTACTGCCGCCGCTGCTTCTTAGTGCCGCGTTCGCCGCCTGGGTTGTCACCGGCGCCG
CCGCCGAGGAAGCCACTGCAACCAGGACCGGAGTGGAGGCGGCGCAGCATGAAGCGGCGCAGGCCCGCTCCATAGCGCACGTCGGGACGGTCCGGGCGGG
GCCGGGGGGAAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGAGCAGAGGGATTCTATGCTTGAAGTCGAGTCACTTGAAAAA
GATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAATGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGAT
ATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAAG
CTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAG
ACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCT
CTCTTGGAAGCCTCTTTTGGATCTTTTTCAGGCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACA
GTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGAT
TTACGCAACAACCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGACTGGATTGCTTT
TATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGCC
AGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTA
AAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTATGTTGGAAACAAGGAGGGCAGATTCATTCCG
TTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTTAAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAA
CTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATC
GCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATTTATCCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCC
TGATTCTGTGACGCCACTAATTATCTATGAAGAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAA
ATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTG
GGCTGCCTGCTCCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATCCA
AGTTGATGAAGTCAGAAGGCTGGTATATTTTGAAGGCACCAAAGACTCCCCTTTAGAGCATCACCTGTACGTAGTCAGTTACGTAAATCCTGGAGAGGTG
ACAAGGCTGACTGACCGTGGCTACTCACATTCTTGCTGCATCAGTCAGCACTGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTG
TGTCCCTTTACAAGCTATCAAGTCCTGAAGATGACCCAACTTGCAAAACAAAGGAATTTTGGGCCACCATTTTGGATTCAGCAGGTCCTCTTCCTGACTA
TACTCCTCCAGAAATTTTCTCTTTTGAAAGTACTACTGGATTTACATTGTATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAGAAATATCCT
ACTGTGCTGTTCATATATGGTGGTCCTCAGGTGCAGTTGGTGAATAATCGGTTTAAAGGAGTCAAGTATTTCCGCTTGAATACCCTAGCCTCTCTAGGTT
ATGTGGTTGTAGTGATAGACAACAGGGGATCCTGTCACCGAGGGCTTAAATTTGAAGGCGCCTTTAAATATAAAATGGTTGCTATTGCTGGGGCCCCAGT
CACTCTGTGGATCTTCTATGATACAGGATACACGGAACGTTATATGGGTCACCCTGACCAGAATGAACAGGGCTATTACTTAGGATCTGTGGCCATGCAA
GCAGAAAAGTTCCCCTCTGAACCAAATCGTTTACTGCTCTTACATGGTTTCCTGGATGAGAATGTCCATTTTGCACATACCAGTATATTACTGAGTTTTT
TAGTGAGGGCTGGAAAGCCATATGATTTACAGATCTATCCTCAGGAGAGACACAGCATAAGAGTTCCTGAATCGGGAGAACATTATGAACTGCATCTTTT
GCACTACCTTCAAGAAAACCTTGGATCACGTATTGCTGCTCTAAAAGTGATATAATTTTGACCTGTGTAGAACTCTCTGGTATACACTGGCTATTTAACC
AAATGAGGAGGTTTAATCAACAGAAAACACAGAATTGATCATCACATTTTGATACCTGCCATGTAACATCTACTCCTGAAAATAAATGTGGTGCCATGCA
GGGGTCTACGGTTTGTGGTAGTAATCTAATACCTTAACCCCACATGCTCAAAATCAAATGATACATATTCCTGAGAGACCCAGCAATACCATAAGAATTA
CTAAAAAAAAAAAAAAAAAAAAGACATTAGCACCATGTATTCATACTACCCTATTTTCACTTTTAATAGTATTATAAACTTCATGAACTTAATTAGTGTA
TTTTTACAGTATACTTTTGAGTTTGTTAAAATATGATGATATTAGTGATTGGTTTGGTTCAGTTCCAGAATCTTTGACTAGTTACAGATTTGATAGCACT
TAAATGTAATTGAATAGCTTATGCTTCATTGCTTGGGCATATCCAGCATGTTATGAACTAATAACTATTAAACTTGACTTAACCAGTCATTCATTAATAA
TTTTTCAAGGATAACTTAGTGGCCTCCTAAAGACACTTGTTTTGGCACTGACCAGTTTTTAGCCAATTTAATCTGTATCTAGTATAAATAATTCTCATTT
TTCTTTGATGATATTAACAGAGTGGGCTTTTCCTTTTGCATAAAGGCTAGTAACTGTATATGTAGCATGGATTTAATTAGTCATGATATTGATAATTACA
GGCAGAAAATTTTTAATCAAATGATTAGAGCTTAAATATTTGCAGGCAAGTTTTTTTTTTTCCTTTAAGAAAAGGAAAAAGTACACATTCACTAGAATTC
TTCAGAAAATTTAGTGGTGCCAGTTTCCATTTGGTATTTCCTTATTAAAATATTCTAGAATTTTAAGGAGATTGAAGGGAATCACAGTGGGGTGGGGAGA
CCTGGGTTTGGGGAATGACAGAGAGAAGAGGTGGTGAGGGCCTGATTAAAAACTAAGCAGAAGTAGTTTTAACAAAAATACTCATGAAAATGTTTGGAAA
CTGAAATTTAAACAACTGTAATATTAAGGAAACCAGAATCAATAAATCACTGTCTTGCCAGCACAGCTACAGAGTAACATGATTCAGGGGAGGAAAAGTT
CCTTAGAGTTACTTTTATAATTCTTTTTTTTTTTCCTCTTAGGTTTAGAAATCTTACAAATTTAAACTTTATCCTTTTA
  • refseq_DPP8.F3 (forward primer)
  • refseq_DPP8.R3 (reverse primer)
  • Single exon skipping

Frame 0

NEPEVLKPPRPRPLLLPPLLLSAAFAAWVVTGA
AAEEATATRTGVEAAQHEAAQARSIAHVGTVRAG
PGGRL*W*GKERFL*EEQDEQRDSMLEVESLEK
DLFECGRDLSR*K*NQENATWQQQWKQNSWVLR
YLKLRTVRRILNHRIGLNWSLFMLSGIPGVSLKS
CLPIPENIMAT*WLRHHMISCL*RGMIQMDLIQ
TESITLPCLVRTEKIHCFILKFPKLSIEQQS*C
SLGSLFWIFFRQHWTMECILEKKNY*EKENALEQ
SELLLTIITKEVEHFCFKPVVEFIT*KMEGHKD
LRNNL*GPI*WKLVVPTYGWIQNYALLIQTGLL
LYIATIFGYLTS*PEKKGDSLMCTMS*PTWKKMP
DQLESLPLFSKKNLIDILAIGGVQKLKQLPVVV
KFLEFYMKKMMNLRWKLFMLHPLCWKQGGQIHS
VILKQVQQILKSLLRCQK**LMLKEGS*MS*IRN
*FNLLRFYLKELNILPELDGLLRENMLGPSY*I
APRLAYR*C*SHLNYLSQ*KMMLWKGRDSLSQC
LIL*RH*LSMKKQQTSG*ISMTSFMFFPKVTKRK
LSLFLPLNAKQVSVIYTKLHLF*RKANINDPVV
GCLLQVISSVLSKRR*QLPVVNGKFLAGMDLIS
KLMKSEGWYILKAPKTPL*SITCT*SVT*ILER*
QG*LTVATHILAASVSTVTSL*VSIVTRRIHTV
CPFTSYQVLKMTQLAKQRNFGPPFWIQQVLFLT
ILLQKFSLLKVLLDLHCMGCSTSLMIYSLERNIL
LCCSYMVVLRCSW*IIGLKESSISA*IP*PL*V
MWL***TTGDPVTEGLNLKAPLNIKWLLLLGPQ
SLCGSSMIQDTRNVIWVTLTRMNRAIT*DLWPCK
QKSSPLNQIVYCSYMVSWMRMSILHIPVYY*VF
**GLESHMIYRSILRRDTA*EFLNRENIMNCIF
CTTFKKTLDHVLLL*K*YNFDLCRTLWYTLAI*P
NEEV*STENTELIITF*YLPCNIYS*K*MWCHA
GVYGLW**SNTLTPHAQNQMIHIPERPSNTIRI
TKKKKKKKTLAPCIHTTLFSLLIVL*TS*T*LVY
FYSILLSLLKYDDISDWFGSVPESLTSYRFDST
*M*LNSLCFIAWAYPACYELITIKLDLTSHSLI
IFQG*LSGLLKTLVLALTSF*PI*SVSSINNSHF
SLMILTEWAFPFA*RLVTVYVAWI*LVMILIIT
GRKFLIK*LELKYLQASFFFSFKKRKKYTFTRI
LQKI*WCQFPFGISLLKYSRILRRLKGITVGWGD
LGLGNDREKRW*GPD*KLSRSSFNKNTHENVWK
LKFKQL*Y*GNQNQ*ITVLPAQLQSNMIQGRKS
SLELLL*FFFFFLLGLEILQI*TLSF

Frame 1

TNRKC*SLRGQGRCYCRRCFLVPRSPPGLSPAP
PPRKPLQPGPEWRRRSMKRRRPAP*RTSGRSGR
GRGEGFDGEERKDSCEKSRMSRGILCLKSSHLKK
ISLNVEEI*ADENKIRKMQHGSSNGNRTAGC*D
I*NCGL*GEY*ITGSA*IGAFLC*AVFLESA*K
AACRYQKISWLHDG*GTT*FHVCEEE*SRWTSFR
QNLLPCHVW*EQRKYTVLF*NSQNYQ*SSSLNA
LLEASFGSFSGNTGLWNVFSRRRTIKRKKTHWN
SRNCFLRLSPRKWNISVSSR*WNLSRKRWRATRI
YATTFKAQSSGN*LSQHTDGSKIMPC*SRLDCF
YT*QRYLDI*HRNQRRKETHLCAQ*ASQHGRRC
QISWSRYLCSPRRI**IFWLLVVSKS*NNSQWW*
NS*NSI*RK**I*GGNYSCYIPYVGNKEGRFIP
LS*NRYSKS*SHF*DVRNND*C*RKDHRCHR*G
TNSTF*DSI*RS*IYCQSWMDS*GKICLVHPTRS
LPDSPTDSVDLT*IIYPSRR*CYGKAETH*VSA
*FCDATNYL*RNNRHLDKYP*HLSCFSPKSRRG
N*VYFCL*MQNRFPSFIQNYIYFKGKQI*TIQWW
AACSK*FQVSYQRGDSNYQW*MGSSWPAWI*YP
S**SQKAGIF*RHQRLPFRASPVRSQLRKSWRG
DKAD*PWLLTFLLHQSAL*LLYK*V**PEESTLC
VPLQAIKS*R*PNLQNKGILGHHFGFSRSSS*L
YSSRNFLF*KYYWIYIVWDALQAS*STAWKEIS
YCAVHIWWSSGAVGE*SV*RSQVFPLEYPSLSRL
CGCSDRQQGILSPRA*I*RRL*I*NGCYCWGPS
HSVDLL*YRIHGTLYGSP*PE*TGLLLRICGHA
SRKVPL*TKSFTALTWFPG*ECPFCTYQYITEFF
SEGWKAI*FTDLSSGETQHKSS*IGRTL*TASF
ALPSRKPWITYCCSKSDIILTCVELSGIHWLFN
QMRRFNQQKTQN*SSHFDTCHVTSTPENKCGAMQ
GSTVCGSNLIP*PHMLKIK*YIFLRDPAIP*EL
LKKKKKKRH*HHVFILPYFHF**YYKLHELN*C
IFTVYF*VC*NMMILVIGLVQFQNL*LVTDLIAL
KCN*IAYASLLGHIQHVMN**LLNLT*PVIH**
FFKDNLVAS*RHLFWH*PVFSQFNLYLV*IILI
FL**Y*QSGLFLLHKG**LYM*HGFN*S*Y**LQ
AENF*SND*SLNICRQVFFFPLRKGKSTHSLEF
FRKFSGASFHLVFPY*NILEF*GD*RESQWGGE
TWVWGMTERRGGEGLIKN*AEVVLTKILMKMFGN
*NLNNCNIKETRINKSLSCQHSYRVT*FRGGKV
P*SYFYNSFFFSS*V*KSYKFKLYPF

Frame 2

RTGSAKASEAKAAATAAAAS*CRVRRLGCHRRR
RRGSHCNQDRSGGGAA*SGAGPLHSARRDGPGG
AGGKALMVRKGKIPVRRAG*AEGFYA*SRVT*K
RSL*MWKRSEQMKIKSGKCNMAAAMETEQLGVEI
FETADCEENIESQDRPKLEPFYVERYSWSQLKK
LLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHS
DRIYYLAMSGENRENTLFYSEIPKTINRAAVLML
SWKPLLDLFQATLDYGMYSREEELLRERKRIGT
VGIASYDYHQGSGTFLFQAGSGIYHVKDGGPQG
FTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAF
IHSNDIWISNIVTREERRLTYVHNELANMEEDA
RSAGVATFVLQEEFDRYSGYWWCPKAETTPSGG
KILRILYEENDESEVEIIHVTSPMLETRRADSFR
YPKTGTANPKVTFKMSEIMIDAEGRIIDVIDKE
LIQPFEILFEGVEYIARAGWTPEGKYAWSILLD
RSQTRLQIVLISPELFIPVEDDVMERQRLIESVP
DSVTPLIIYEETTDIWINIHDIFHVFPQSHEEE
IEFIFASECKTGFRHLYKITSILKESKYKRSSG
GLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQ
VDEVRRLVYFEGTKDSPLEHHLYVVSYVNPGEV
TRLTDRGYSHSCCISQHCDFFISKYSNQKNPHC
VSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDY
TPPEIFSFESTTGFTLYGMLYKPHDLQPGKKYP
TVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLG
YVVVVIDNRGSCHRGLKFEGAFKYKMVAIAGAPV
TLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQ
AEKFPSEPNRLLLLHGFLDENVHFAHTSILLSF
LVRAGKPYDLQIYPQERHSIRVPESGEHYELHLL
HYLQENLGSRIAALKVI*F*PV*NSLVYTGYLT
K*GGLINRKHRIDHHILIPAM*HLLLKINVVPC
RGLRFVVVI*YLNPTCSKSNDTYS*ETQQYHKNY
*KKKKKKDISTMYSYYPIFTFNSIINFMNLISV
FLQYTFEFVKI**Y**LVWFSSRIFD*LQI**H
LNVIE*LMLHCLGISSML*TNNY*T*LNQSFINN
FSRIT*WPPKDTCFGTDQFLANLICI*YK*FSF
FFDDINRVGFSFCIKASNCICSMDLISHDIDNY
RQKIFNQMIRA*IFAGKFFFFL*EKEKVHIH*NS
SENLVVPVSIWYFLIKIF*NFKEIEGNHSGVGR
PGFGE*QREEVVRA*LKTKQK*F*QKYS*KCLE
TEI*TTVILRKPESINHCLASTATE*HDSGEEKF
LRVTFIILFFFPLRFRNLTNLNFILL

Sequence NM_197960

ATTCCGAGTCAACCACCGTTCACTGGGCGCCCCTTGAGCTCTGGGCGCTGGCCTCCTGGCTTCCACGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGA
GAAGAGCAGGATGAGCAGAGGGATTCTATGCTTGAAGTCGAGTCACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATC
AGGAAAATGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAGGATCGG
CCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGG
CACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATAC
ACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAGGCAACACTGGACTAT
GGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTC
TGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCC
CAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAA
GAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATA
GATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGA
AATTATTCATGTTACATCCCCTATGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTTAAGATG
TCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTG
CCAGAGCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATT
TATCCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAAGAAACAACAGACATC
TGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATT
TATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGAT
AGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATCCAAGTTGATGAAGTCAGAAGGCTGGTATATTTTGAAGGCACCAAAGAC
TCCCCTTTAGAGCATCACCTGTACGTAGTCAGTTACGTAAATCCTGGAGAGGTGACAAGGCTGACTGACCGTGGCTACTCACATTCTTGCTGCATCAGTC
AGCACTGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTGTGTCCCTTTACAAGCTATCAAGTCCTGAAGATGACCCAACTTGCAA
AACAAAGGAATTTTGGGCCACCATTTTGGATTCAGCAGGTCCTCTTCCTGACTATACTCCTCCAGAAATTTTCTCTTTTGAAAGTACTACTGGATTTACA
TTGTATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAGAAATATCCTACTGTGCTGTTCATATATGGTGGTCCTCAGGTGCAGTTGGTGAATA
ATCGGTTTAAAGGAGTCAAGTATTTCCGCTTGAATACCCTAGCCTCTCTAGGTTATGTGGTTGTAGTGATAGACAACAGGGGATCCTGTCACCGAGGGCT
TAAATTTGAAGGCGCCTTTAAATATAAAATGGGTCAAATAGAAATTGACGATCAGGTGGAAGGACTCCAATATCTAGCTTCTCGATATGATTTCATTGAC
TTAGATCGTGTGGGCATCCACGGCTGGTCCTATGGAGGATACCTCTCCCTGATGGCATTAATGCAGAGGTCAGATATCTTCAGG
GTTGCTATTGCTGGGG
CCCCAGTCACTCTGTGGATCTTCTATGATACAGGATACACGGAACGTTATATGGGTCACCCTGACCAGAATGAACAGGGCTATTACTTAGGATCTGTGGC
CATGCAAGCAGAAAAGTTCCCCTCTGAACCAAATCGTTTACTGCTCTTACATGGTTTCCTGGATGAGAATGTCCATTTTGCACATACCAGTATATTACTG
AGTTTTTTAGTGAGGGCTGGAAAGCCATATGATTTACAGATCTATCCTCAGGAGAGACACAGCATAAGAGTTCCTGAATCGGGAGAACATTATGAACTGC
ATCTTTTGCACTACCTTCAAGAAAACCTTGGATCACGTATTGCTGCTCTAAAAGTGATATAATTTTGACCTGTGTAGAACTCTCTGGTATACACTGGCTA
TTTAACCAAATGAGGAGGTTTAATCAACAGAAAACACAGAATTGATCATCACATTTTGATACCTGCCATGTAACATCTACTCCTGAAAATAAATGTGGTG
CCATGCAGGGGTCTACGGTTTGTGGTAGTAATCTAATACCTTAACCCCACATGCTCAAAATCAAATGATACATATTCCTGAGAGACCCAGCAATACCATA
AGAATTACTAAAAAAAAAAAAAAAAAAAAGACATTAGCACCATGTATTCATACTACCCTATTTTCACTTTTAATAGTATTATAAACTTCATGAACTTAAT
TAGTGTATTTTTACAGTATACTTTTGAGTTTGTTAAAATATGATGATATTAGTGATTGGTTTGGTTCAGTTCCAGAATCTTTGACTAGTTACAGATTTGA
TAGCACTTAAATGTAATTGAATAGCTTATGCTTCATTGCTTGGGCATATCCAGCATGTTATGAACTAATAACTATTAAACTTGACTTAACCAGTCATTCA
TTAATAATTTTTCAAGGATAACTTAGTGGCCTCCTAAAGACACTTGTTTTGGCACTGACCAGTTTTTAGCCAATTTAATCTGTATCTAGTATAAATAATT
CTCATTTTTCTTTGATGATATTAACAGAGTGGGCTTTTCCTTTTGCATAAAGGCTAGTAACTGTATATGTAGCATGGATTTAATTAGTCATGATATTGAT
AATTACAGGCAGAAAATTTTTAATCAAATGATTAGAGCTTAAATATTTGCAGGCAAGTTTTTTTTTTTCCTTTAAGAAAAGGAAAAAGTACACATTCACT
AGAATTCTTCAGAAAATTTAGTGGTGCCAGTTTCCATTTGGTATTTCCTTATTAAAATATTCTAGAATTTTAAGGAGATTGAAGGGAATCACAGTGGGGT
GGGGAGACCTGGGTTTGGGGAATGACAGAGAGAAGAGGTGGTGAGGGCCTGATTAAAAACTAAGCAGAAGTAGTTTTAACAAAAATACTCATGAAAATGT
TTGGAAACTGAAATTTAAACAACTGTAATATTAAGGAAACCAGAATCAATAAATCACTGTCTTGCCAGCACAGCTACAGAGTAACATGATTCAGGGGAGG
AAAAGTTCCTTAGAGTTACTTTTATAATTCTTTTTTTTTTTCCTCTTAGGTTTAGAAATCTTACAAATTTAAACTTTATCCTTTTA
  • refseq_DPP8.F3 (forward primer)
  • refseq_DPP8.R3 (reverse primer)
  • Single exon skipping

Frame 0

IPSQPPFTGRPLSSGRWPPGFHALMVRKGKIPV
RRAG*AEGFYA*SRVT*KRSL*MWKRSEQMKIKS
GKCNMAAAMETEQLGVEIFETADCEENIESQDR
PKLEPFYVERYSWSQLKKLLADTRKYHGYMMAK
APHDFMFVKRNDPDGPHSDRIYYLAMSGENRENT
LFYSEIPKTINRAAVLMLSWKPLLDLFQATLDY
GMYSREEELLRERKRIGTVGIASYDYHQGSGTF
LFQAGSGIYHVKDGGPQGFTQQPLRPNLVETSCP
NIRMDPKLCPADPDWIAFIHSNDIWISNIVTRE
ERRLTYVHNELANMEEDARSAGVATFVLQEEFD
RYSGYWWCPKAETTPSGGKILRILYEENDESEVE
IIHVTSPMLETRRADSFRYPKTGTANPKVTFKM
SEIMIDAEGRIIDVIDKELIQPFEILFEGVEYI
ARAGWTPEGKYAWSILLDRSQTRLQIVLISPELF
IPVEDDVMERQRLIESVPDSVTPLIIYEETTDI
WINIHDIFHVFPQSHEEEIEFIFASECKTGFRH
LYKITSILKESKYKRSSGGLPAPSDFKCPIKEEI
AITSGEWEVLGRHGSNIQVDEVRRLVYFEGTKD
SPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCIS
QHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCK
TKEFWATILDSAGPLPDYTPPEIFSFESTTGFT
LYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVN
NRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGL
KFEGAFKYKMGQIEIDDQVEGLQYLASRYDFID
LDRVGIHGWSYGGYLSLMALMQRSDIFR
VAIAG
APVTLWIFYDTGYTERYMGHPDQNEQGYYLGSVA
MQAEKFPSEPNRLLLLHGFLDENVHFAHTSILL
SFLVRAGKPYDLQIYPQERHSIRVPESGEHYEL
HLLHYLQENLGSRIAALKVI*F*PV*NSLVYTGY
LTK*GGLINRKHRIDHHILIPAM*HLLLKINVV
PCRGLRFVVVI*YLNPTCSKSNDTYS*ETQQYH
KNY*KKKKKKDISTMYSYYPIFTFNSIINFMNLI
SVFLQYTFEFVKI**Y**LVWFSSRIFD*LQI*
*HLNVIE*LMLHCLGISSML*TNNY*T*LNQSF
INNFSRIT*WPPKDTCFGTDQFLANLICI*YK*F
SFFFDDINRVGFSFCIKASNCICSMDLISHDID
NYRQKIFNQMIRA*IFAGKFFFFL*EKEKVHIH
*NSSENLVVPVSIWYFLIKIF*NFKEIEGNHSGV
GRPGFGE*QREEVVRA*LKTKQK*F*QKYS*KC
LETEI*TTVILRKPESINHCLASTATE*HDSGE
EKFLRVTFIILFFFPLRFRNLTNLNFILL

Frame 1

FRVNHRSLGAP*ALGAGLLASTL*W*GKERFL*
EEQDEQRDSMLEVESLEKDLFECGRDLSR*K*N
QENATWQQQWKQNSWVLRYLKLRTVRRILNHRIG
LNWSLFMLSGIPGVSLKSCLPIPENIMAT*WLR
HHMISCL*RGMIQMDLIQTESITLPCLVRTEKI
HCFILKFPKLSIEQQS*CSLGSLFWIFFRQHWTM
ECILEKKNY*EKENALEQSELLLTIITKEVEHF
CFKPVVEFIT*KMEGHKDLRNNL*GPI*WKLVV
PTYGWIQNYALLIQTGLLLYIATIFGYLTS*PEK
KGDSLMCTMS*PTWKKMPDQLESLPLFSKKNLI
DILAIGGVQKLKQLPVVVKFLEFYMKKMMNLRW
KLFMLHPLCWKQGGQIHSVILKQVQQILKSLLRC
QK**LMLKEGS*MS*IRN*FNLLRFYLKELNIL
PELDGLLRENMLGPSY*IAPRLAYR*C*SHLNY
LSQ*KMMLWKGRDSLSQCLIL*RH*LSMKKQQTS
G*ISMTSFMFFPKVTKRKLSLFLPLNAKQVSVI
YTKLHLF*RKANINDPVVGCLLQVISSVLSKRR
*QLPVVNGKFLAGMDLISKLMKSEGWYILKAPKT
PL*SITCT*SVT*ILER*QG*LTVATHILAASV
STVTSL*VSIVTRRIHTVCPFTSYQVLKMTQLA
KQRNFGPPFWIQQVLFLTILLQKFSLLKVLLDLH
CMGCSTSLMIYSLERNILLCCSYMVVLRCSW*I
IGLKESSISA*IP*PL*VMWL***TTGDPVTEG
LNLKAPLNIKWVK*KLTIRWKDSNI*LLDMISLT
*IVWASTAGPMEDTSP*WH*CRGQISSG
LLLLG
PQSLCGSSMIQDTRNVIWVTLTRMNRAIT*DLW
PCKQKSSPLNQIVYCSYMVSWMRMSILHIPVYY*
VF**GLESHMIYRSILRRDTA*EFLNRENIMNC
IFCTTFKKTLDHVLLL*K*YNFDLCRTLWYTLA
I*PNEEV*STENTELIITF*YLPCNIYS*K*MWC
HAGVYGLW**SNTLTPHAQNQMIHIPERPSNTI
RITKKKKKKKTLAPCIHTTLFSLLIVL*TS*T*
LVYFYSILLSLLKYDDISDWFGSVPESLTSYRFD
ST*M*LNSLCFIAWAYPACYELITIKLDLTSHS
LIIFQG*LSGLLKTLVLALTSF*PI*SVSSINN
SHFSLMILTEWAFPFA*RLVTVYVAWI*LVMILI
ITGRKFLIK*LELKYLQASFFFSFKKRKKYTFT
RILQKI*WCQFPFGISLLKYSRILRRLKGITVG
WGDLGLGNDREKRW*GPD*KLSRSSFNKNTHENV
WKLKFKQL*Y*GNQNQ*ITVLPAQLQSNMIQGR
KSSLELLL*FFFFFLLGLEILQI*TLSF

Frame 2

SESTTVHWAPLELWALASWLPRFDGEERKDSCE
KSRMSRGILCLKSSHLKKISLNVEEI*ADENKI
RKMQHGSSNGNRTAGC*DI*NCGL*GEY*ITGS
A*IGAFLC*AVFLESA*KAACRYQKISWLHDG*G
TT*FHVCEEE*SRWTSFRQNLLPCHVW*EQRKY
TVLF*NSQNYQ*SSSLNALLEASFGSFSGNTGL
WNVFSRRRTIKRKKTHWNSRNCFLRLSPRKWNIS
VSSR*WNLSRKRWRATRIYATTFKAQSSGN*LS
QHTDGSKIMPC*SRLDCFYT*QRYLDI*HRNQR
RKETHLCAQ*ASQHGRRCQISWSRYLCSPRRI**
IFWLLVVSKS*NNSQWW*NS*NSI*RK**I*GG
NYSCYIPYVGNKEGRFIPLS*NRYSKS*SHF*D
VRNND*C*RKDHRCHR*GTNSTF*DSI*RS*IYC
QSWMDS*GKICLVHPTRSLPDSPTDSVDLT*II
YPSRR*CYGKAETH*VSA*FCDATNYL*RNNRH
LDKYP*HLSCFSPKSRRGN*VYFCL*MQNRFPSF
IQNYIYFKGKQI*TIQWWAACSK*FQVSYQRGD
SNYQW*MGSSWPAWI*YPS**SQKAGIF*RHQR
LPFRASPVRSQLRKSWRGDKAD*PWLLTFLLHQS
AL*LLYK*V**PEESTLCVPLQAIKS*R*PNLQ
NKGILGHHFGFSRSSS*LYSSRNFLF*KYYWIY
IVWDALQAS*STAWKEISYCAVHIWWSSGAVGE*
SV*RSQVFPLEYPSLSRLCGCSDRQQGILSPRA
*I*RRL*I*NGSNRN*RSGGRTPISSFSI*FH*
LRSCGHPRLVLWRIPLPDGINAEVRYLQ
GCYCWG
PSHSVDLL*YRIHGTLYGSP*PE*TGLLLRICG
HASRKVPL*TKSFTALTWFPG*ECPFCTYQYIT
EFFSEGWKAI*FTDLSSGETQHKSS*IGRTL*TA
SFALPSRKPWITYCCSKSDIILTCVELSGIHWL
FNQMRRFNQQKTQN*SSHFDTCHVTSTPENKCG
AMQGSTVCGSNLIP*PHMLKIK*YIFLRDPAIP*
ELLKKKKKKRH*HHVFILPYFHF**YYKLHELN
*CIFTVYF*VC*NMMILVIGLVQFQNL*LVTDL
IALKCN*IAYASLLGHIQHVMN**LLNLT*PVIH
**FFKDNLVAS*RHLFWH*PVFSQFNLYLV*II
LIFL**Y*QSGLFLLHKG**LYM*HGFN*S*Y*
*LQAENF*SND*SLNICRQVFFFPLRKGKSTHSL
EFFRKFSGASFHLVFPY*NILEF*GD*RESQWG
GETWVWGMTERRGGEGLIKN*AEVVLTKILMKM
FGN*NLNNCNIKETRINKSLSCQHSYRVT*FRGG
KVP*SYFYNSFFFSS*V*KSYKFKLYPF

Sequence NM_130434

AACGAACCGGAAGTGCTAAAGCCTCCGAGGCCAAGGCCGCTGCTACTGCCGCCGCTGCTTCTTAGTGCCGCGTTCGCCGCCTGGGTTGTCACCGGCGCCG
CCGCCGAGGAAGCCACTGCAACCAGGACCGGAGTGGAGGCGGCGCAGCATGAAGCGGCGCAGGCCCGCTCCATAGCGCACGTCGGGACGGTCCGGGCGGG
GCCGGGGGGAAGGAAAATGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATC
ACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATG
ATGGCTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACA
GAGAAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAGGCAAC
ACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCAAGGAAGT
GGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAGGCCCAATCTAGTGGAAA
CTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGT
AACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAA
GAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAAT
CTGAGGTGGAAATTATTCATGTTACATCCCCTATGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCAC
TTTTAAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTT
GAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCAC
CTGAATTATTTATCCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAAGAAAC
AACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGT
TTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGTCCTATCA
AAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATCCAAGTTGATGAAGTCAGAAGGCTGGTATATTTTGAAGG
CACCAAAGACTCCCCTTTAGAGCATCACCTGTACGTAGTCAGTTACGTAAATCCTGGAGAGGTGACAAGGCTGACTGACCGTGGCTACTCACATTCTTGC
TGCATCAGTCAGCACTGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTGTGTCCCTTTACAAGCTATCAAGTCCTGAAGATGACC
CAACTTGCAAAACAAAGGAATTTTGGGCCACCATTTTGGATTCAGCAGGTCCTCTTCCTGACTATACTCCTCCAGAAATTTTCTCTTTTGAAAGTACTAC
TGGATTTACATTGTATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAGAAATATCCTACTGTGCTGTTCATATATGGTGGTCCTCAGGTGCAG
TTGGTGAATAATCGGTTTAAAGGAGTCAAGTATTTCCGCTTGAATACCCTAGCCTCTCTAGGTTATGTGGTTGTAGTGATAGACAACAGGGGATCCTGTC
ACCGAGGGCTTAAATTTGAAGGCGCCTTTAAATATAAAATGGGTCAAATAGAAATTGACGATCAGGTGGAAGGACTCCAATATCTAGCTTCTCGATATGA
TTTCATTGACTTAGATCGTGTGGGCATCCACGGCTGGTCCTATGGAGGATACCTCTCCCTGATGGCATTAATGCAGAGGTCAGATATCTTCAGG
GTTGCT
ATTGCTGGGGCCCCAGTCACTCTGTGGATCTTCTATGATACAGGATACACGGAACGTTATATGGGTCACCCTGACCAGAATGAACAGGGCTATTACTTAG
GATCTGTGGCCATGCAAGCAGAAAAGTTCCCCTCTGAACCAAATCGTTTACTGCTCTTACATGGTTTCCTGGATGAGAATGTCCATTTTGCACATACCAG
TATATTACTGAGTTTTTTAGTGAGGGCTGGAAAGCCATATGATTTACAGATCTATCCTCAGGAGAGACACAGCATAAGAGTTCCTGAATCGGGAGAACAT
TATGAACTGCATCTTTTGCACTACCTTCAAGAAAACCTTGGATCACGTATTGCTGCTCTAAAAGTGATATAATTTTGACCTGTGTAGAACTCTCTGGTAT
ACACTGGCTATTTAACCAAATGAGGAGGTTTAATCAACAGAAAACACAGAATTGATCATCACATTTTGATACCTGCCATGTAACATCTACTCCTGAAAAT
AAATGTGGTGCCATGCAGGGGTCTACGGTTTGTGGTAGTAATCTAATACCTTAACCCCACATGCTCAAAATCAAATGATACATATTCCTGAGAGACCCAG
CAATACCATAAGAATTACTAAAAAAAAAAAAAAAAAAAAGACATTAGCACCATGTATTCATACTACCCTATTTTCACTTTTAATAGTATTATAAACTTCA
TGAACTTAATTAGTGTATTTTTACAGTATACTTTTGAGTTTGTTAAAATATGATGATATTAGTGATTGGTTTGGTTCAGTTCCAGAATCTTTGACTAGTT
ACAGATTTGATAGCACTTAAATGTAATTGAATAGCTTATGCTTCATTGCTTGGGCATATCCAGCATGTTATGAACTAATAACTATTAAACTTGACTTAAC
CAGTCATTCATTAATAATTTTTCAAGGATAACTTAGTGGCCTCCTAAAGACACTTGTTTTGGCACTGACCAGTTTTTAGCCAATTTAATCTGTATCTAGT
ATAAATAATTCTCATTTTTCTTTGATGATATTAACAGAGTGGGCTTTTCCTTTTGCATAAAGGCTAGTAACTGTATATGTAGCATGGATTTAATTAGTCA
TGATATTGATAATTACAGGCAGAAAATTTTTAATCAAATGATTAGAGCTTAAATATTTGCAGGCAAGTTTTTTTTTTTCCTTTAAGAAAAGGAAAAAGTA
CACATTCACTAGAATTCTTCAGAAAATTTAGTGGTGCCAGTTTCCATTTGGTATTTCCTTATTAAAATATTCTAGAATTTTAAGGAGATTGAAGGGAATC
ACAGTGGGGTGGGGAGACCTGGGTTTGGGGAATGACAGAGAGAAGAGGTGGTGAGGGCCTGATTAAAAACTAAGCAGAAGTAGTTTTAACAAAAATACTC
ATGAAAATGTTTGGAAACTGAAATTTAAACAACTGTAATATTAAGGAAACCAGAATCAATAAATCACTGTCTTGCCAGCACAGCTACAGAGTAACATGAT
TCAGGGGAGGAAAAGTTCCTTAGAGTTACTTTTATAATTCTTTTTTTTTTTCCTCTTAGGTTTAGAAATCTTACAAATTTAAACTTTATCCTTTTA
  • refseq_DPP8.F3 (forward primer)
  • refseq_DPP8.R3 (reverse primer)
  • Single exon skipping

Frame 0

NEPEVLKPPRPRPLLLPPLLLSAAFAAWVVTGA
AAEEATATRTGVEAAQHEAAQARSIAHVGTVRAG
PGGRKMQHGSSNGNRTAGC*DI*NCGL*GEY*I
TGSA*IGAFLC*AVFLESA*KAACRYQKISWLH
DG*GTT*FHVCEEE*SRWTSFRQNLLPCHVW*EQ
RKYTVLF*NSQNYQ*SSSLNALLEASFGSFSGN
TGLWNVFSRRRTIKRKKTHWNSRNCFLRLSPRK
WNISVSSR*WNLSRKRWRATRIYATTFKAQSSGN
*LSQHTDGSKIMPC*SRLDCFYT*QRYLDI*HR
NQRRKETHLCAQ*ASQHGRRCQISWSRYLCSPR
RI**IFWLLVVSKS*NNSQWW*NS*NSI*RK**I
*GGNYSCYIPYVGNKEGRFIPLS*NRYSKS*SH
F*DVRNND*C*RKDHRCHR*GTNSTF*DSI*RS
*IYCQSWMDS*GKICLVHPTRSLPDSPTDSVDLT
*IIYPSRR*CYGKAETH*VSA*FCDATNYL*RN
NRHLDKYP*HLSCFSPKSRRGN*VYFCL*MQNR
FPSFIQNYIYFKGKQI*TIQWWAACSK*FQVSYQ
RGDSNYQW*MGSSWPAWI*YPS**SQKAGIF*R
HQRLPFRASPVRSQLRKSWRGDKAD*PWLLTFL
LHQSAL*LLYK*V**PEESTLCVPLQAIKS*R*P
NLQNKGILGHHFGFSRSSS*LYSSRNFLF*KYY
WIYIVWDALQAS*STAWKEISYCAVHIWWSSGA
VGE*SV*RSQVFPLEYPSLSRLCGCSDRQQGILS
PRA*I*RRL*I*NGSNRN*RSGGRTPISSFSI*
FH*LRSCGHPRLVLWRIPLPDGINAEVRYLQ
GC
YCWGPSHSVDLL*YRIHGTLYGSP*PE*TGLLLR
ICGHASRKVPL*TKSFTALTWFPG*ECPFCTYQ
YITEFFSEGWKAI*FTDLSSGETQHKSS*IGRT
L*TASFALPSRKPWITYCCSKSDIILTCVELSGI
HWLFNQMRRFNQQKTQN*SSHFDTCHVTSTPEN
KCGAMQGSTVCGSNLIP*PHMLKIK*YIFLRDP
AIP*ELLKKKKKKRH*HHVFILPYFHF**YYKLH
ELN*CIFTVYF*VC*NMMILVIGLVQFQNL*LV
TDLIALKCN*IAYASLLGHIQHVMN**LLNLT*
PVIH**FFKDNLVAS*RHLFWH*PVFSQFNLYLV
*IILIFL**Y*QSGLFLLHKG**LYM*HGFN*S
*Y**LQAENF*SND*SLNICRQVFFFPLRKGKS
THSLEFFRKFSGASFHLVFPY*NILEF*GD*RES
QWGGETWVWGMTERRGGEGLIKN*AEVVLTKIL
MKMFGN*NLNNCNIKETRINKSLSCQHSYRVT*
FRGGKVP*SYFYNSFFFSS*V*KSYKFKLYPF

Frame 1

TNRKC*SLRGQGRCYCRRCFLVPRSPPGLSPAP
PPRKPLQPGPEWRRRSMKRRRPAP*RTSGRSGR
GRGEGKCNMAAAMETEQLGVEIFETADCEENIES
QDRPKLEPFYVERYSWSQLKKLLADTRKYHGYM
MAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGEN
RENTLFYSEIPKTINRAAVLMLSWKPLLDLFQAT
LDYGMYSREEELLRERKRIGTVGIASYDYHQGS
GTFLFQAGSGIYHVKDGGPQGFTQQPLRPNLVE
TSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIV
TREERRLTYVHNELANMEEDARSAGVATFVLQE
EFDRYSGYWWCPKAETTPSGGKILRILYEENDE
SEVEIIHVTSPMLETRRADSFRYPKTGTANPKVT
FKMSEIMIDAEGRIIDVIDKELIQPFEILFEGV
EYIARAGWTPEGKYAWSILLDRSQTRLQIVLIS
PELFIPVEDDVMERQRLIESVPDSVTPLIIYEET
TDIWINIHDIFHVFPQSHEEEIEFIFASECKTG
FRHLYKITSILKESKYKRSSGGLPAPSDFKCPI
KEEIAITSGEWEVLGRHGSNIQVDEVRRLVYFEG
TKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSC
CISQHCDFFISKYSNQKNPHCVSLYKLSSPEDD
PTCKTKEFWATILDSAGPLPDYTPPEIFSFESTT
GFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQ
LVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSC
HRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYD
FIDLDRVGIHGWSYGGYLSLMALMQRSDIFR
VA
IAGAPVTLWIFYDTGYTERYMGHPDQNEQGYYL
GSVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTS
ILLSFLVRAGKPYDLQIYPQERHSIRVPESGEH
YELHLLHYLQENLGSRIAALKVI*F*PV*NSLV
YTGYLTK*GGLINRKHRIDHHILIPAM*HLLLKI
NVVPCRGLRFVVVI*YLNPTCSKSNDTYS*ETQ
QYHKNY*KKKKKKDISTMYSYYPIFTFNSIINF
MNLISVFLQYTFEFVKI**Y**LVWFSSRIFD*L
QI**HLNVIE*LMLHCLGISSML*TNNY*T*LN
QSFINNFSRIT*WPPKDTCFGTDQFLANLICI*
YK*FSFFFDDINRVGFSFCIKASNCICSMDLISH
DIDNYRQKIFNQMIRA*IFAGKFFFFL*EKEKV
HIH*NSSENLVVPVSIWYFLIKIF*NFKEIEGN
HSGVGRPGFGE*QREEVVRA*LKTKQK*F*QKYS
*KCLETEI*TTVILRKPESINHCLASTATE*HD
SGEEKFLRVTFIILFFFPLRFRNLTNLNFILL

Frame 2

RTGSAKASEAKAAATAAAAS*CRVRRLGCHRRR
RRGSHCNQDRSGGGAA*SGAGPLHSARRDGPGG
AGGKENATWQQQWKQNSWVLRYLKLRTVRRILN
HRIGLNWSLFMLSGIPGVSLKSCLPIPENIMAT*
WLRHHMISCL*RGMIQMDLIQTESITLPCLVRT
EKIHCFILKFPKLSIEQQS*CSLGSLFWIFFRQ
HWTMECILEKKNY*EKENALEQSELLLTIITKEV
EHFCFKPVVEFIT*KMEGHKDLRNNL*GPI*WK
LVVPTYGWIQNYALLIQTGLLLYIATIFGYLTS
*PEKKGDSLMCTMS*PTWKKMPDQLESLPLFSKK
NLIDILAIGGVQKLKQLPVVVKFLEFYMKKMMN
LRWKLFMLHPLCWKQGGQIHSVILKQVQQILKS
LLRCQK**LMLKEGS*MS*IRN*FNLLRFYLKEL
NILPELDGLLRENMLGPSY*IAPRLAYR*C*SH
LNYLSQ*KMMLWKGRDSLSQCLIL*RH*LSMKK
QQTSG*ISMTSFMFFPKVTKRKLSLFLPLNAKQV
SVIYTKLHLF*RKANINDPVVGCLLQVISSVLS
KRR*QLPVVNGKFLAGMDLISKLMKSEGWYILK
APKTPL*SITCT*SVT*ILER*QG*LTVATHILA
ASVSTVTSL*VSIVTRRIHTVCPFTSYQVLKMT
QLAKQRNFGPPFWIQQVLFLTILLQKFSLLKVL
LDLHCMGCSTSLMIYSLERNILLCCSYMVVLRCS
W*IIGLKESSISA*IP*PL*VMWL***TTGDPV
TEGLNLKAPLNIKWVK*KLTIRWKDSNI*LLDM
ISLT*IVWASTAGPMEDTSP*WH*CRGQISSG
LL
LLGPQSLCGSSMIQDTRNVIWVTLTRMNRAIT*
DLWPCKQKSSPLNQIVYCSYMVSWMRMSILHIP
VYY*VF**GLESHMIYRSILRRDTA*EFLNRENI
MNCIFCTTFKKTLDHVLLL*K*YNFDLCRTLWY
TLAI*PNEEV*STENTELIITF*YLPCNIYS*K
*MWCHAGVYGLW**SNTLTPHAQNQMIHIPERPS
NTIRITKKKKKKKTLAPCIHTTLFSLLIVL*TS
*T*LVYFYSILLSLLKYDDISDWFGSVPESLTS
YRFDST*M*LNSLCFIAWAYPACYELITIKLDLT
SHSLIIFQG*LSGLLKTLVLALTSF*PI*SVSS
INNSHFSLMILTEWAFPFA*RLVTVYVAWI*LV
MILIITGRKFLIK*LELKYLQASFFFSFKKRKKY
TFTRILQKI*WCQFPFGISLLKYSRILRRLKGI
TVGWGDLGLGNDREKRW*GPD*KLSRSSFNKNT
HENVWKLKFKQL*Y*GNQNQ*ITVLPAQLQSNMI
QGRKSSLELLL*FFFFFLLGLEILQI*TLSF

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