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Sequences

Sequence NM_033498

AAAACATCTATCTTGCTGTGTTTGGACAGGCCAGCCCCTGAAACATCTTGGGCAATGGAGGGTTAACTTCTCAAAGTTTAATAGGCAAGACCAGCAACCA TGCAACAAGGACTTCAACTAACCAACTAAAGAACTGTTCCCCAGAGCATTGTTCCTGAGAAGGAAAAGAGTCCAAACACCTACCCACACCTGCTTTGTGC CAAGAATCCACAGTTGGATTGCAAGGACAGTGTATGTTGTCCTTTTGGAAAAATGAGAGTGAGCCCAAATGAAGAACAAGCAAAGGCGTTCAAGACCCAG CTGTTGAGAGTAGAAAAGCAGAAGAAAGGACCCGAGGTCAGCAAGTGCCCTCCCCACAATGGGGCAGATCTGCCAGCGAGAATCGGCTACAGCAGCTGAA AAACCAAAACTTCATCTACTTGCTGAAAGTGAGATTGACAAGTATCTCTATGCCATGCGGCTCTCCGATGAAACTCTCATAGATATCATGACTCGCTTCA GGAAGGAGATGAAGAATGGCCTCTCCCGGGATTTTAATCCAACAGCCACAGTCAAGATGTTGCCAACATTCGTAAGGTCCATTCCTGATGGCTCTGAAAA GGGAGATTTCATTGCCCTGGATCTTGGTGGGTCTTCCTTTCGAATTCTGCGGGTGCAAGTGAATCATGAGAAAAACCAGAATGTTCACATGGAGTCCGAG GTTTATGACACCCCAGAGAACATCGTGCACGGCAGTGGAAGCCAGCTTTTTGATCATGTTGCTGAGTGCCTGGGAGATTTCATGGAGAAAAGGAAGATCA AGGACAAGAAGTTACCTGTGGGATTCACGTTTTCTTTTCCTTGCCAACAATCCAAAATAGATGAGGCCATCCTGATCACCTGGACAAAGCGATTTAAAGC GAGCGGAGTGGAAGGAGCAGATGTGGTCAAACTGCTTAACAAAGCCATCAAAAAGCGAGGGGACTATGATGCCAACATCGTAGCTGTGGTGAATGACACA GTGGGCACCATGATGACCTGTGGCTATGACGACCAGCACTGTGAAGTCGGCCTGATCATCGGCACTGGCACCAATGCTTGCTACATGGAGGAACTGAGGC ACATTGATCTGGTGGAAGGAGACGAGGGGAGGATGTGTATCAATACAGAATGGGGAGCCTTTGGAGACGATGGATCATTAGAAGACATCCGGACAGAGTT TGACAGGGAGATAGACCGGGGATCCCTCAACCCTGGAAAACAGCTGTTTGAGAAGATGGTCAGTGGCATGTACTTGGGAGAGCTGGTTCGACTGATCCTA GTCAAGATGGCCAAGGAGGGCCTCTTATTTGAAGGGCGGATCACCCCGGAGCTGCTCACCCGAGGGAAGTTTAACACCAGTGATGTGTCAGCCATCGAAA AGAATAAGGAAGGCCTCCACAATGCCAAAGAAATCCTGACCCGCCTGGGAGTGGAGCCGTCCGATGATGACTGTGTCTCAGTCCAGCACGTTTGCACCAT TGTCTCATTTCGCTCAGCCAACTTGGTGGCTGCCACACTGGGCGCCATCTTGAACCGCCTGCGTGATAACAAGGGCACACCCAGGCTGCGGACCACGGTT GGTGTCGACGGATCTCTTTACAAGACGCACCCACAGTATTCCCGGCGTTTCCACAAGACTCTAAGGCGCTTGGTGCCAGACTCCGATGTGCGCTTCCTCC TCTCGGAGAGTGGCAGCGGCAAGGGGGCTGCCATGGTGACGGCGGTGGCCTACCGCTTGGCCGAGCAGCACCGGCAGATAGAGGAGACCCTGGCTCATTT CCACCTCACCAAGGACATGCTGCTGGAGGTGAAGAAGAGGATGCGGGCCGAGATGGAGCTGGGGCTGAGGAAGCAGACGCACAACAATGCCGTGGTTAAG ATGCTGCCCTCCTTCGTCCGGAGAACTCCCGACGGGACCGAGAATGGTGACTTCTTGGCCCTGGATCTTGGAGGAACCAATTTCCGTGTGCTGCTGGTGA AAATCCGTAGTGGGAAAAAGAGAACGGTGGAAATGCACAACAAGATCTACGCCATTCCTATTGAAATCATGCAGGGCACTGGGGAAGAGCTGTTTGATCA CATTGTCTCCTGCATCTCTGACTTCTTGGACTACATGGGGATCAAAGGCCCCAGGATGCCTCTGGGCTTCACGTTCTCATTTCCCTGCCAGCAGACGAGT CTGGACGCGGGAATCTTGATCACGTGGACAAAGGGTTTTAAGGCAACAGACTGCGTGGGCCACGATGTAGTCACCTTACTAAGGGATGCGATAAAAAGGA GAGAGGAATTTGACCTGGACGTGGTGGCTGTGGTCAACGACACAGTGGGCACCATGATGACCTGTGCTTATGAGGAGCCCACCTGTGAGGTTGGACTCAT TGTTGGGACCGGCAGCAATGCCTGCTACATGGAGGAGATGAAGAACGTGGAGATGGTGGAGGGGGACCAGGGGCAGATGTGCATCAACATGGAGTGGGGG GCCTTTGGGGACAACGGGTGTCTGGATGATATCAGGACACACTACGACAGACTGGTGGACGAATATTCCCTAAATGCTGGGAAACAAAGGTATGAGAAGA TGATCAGTGGTATGTACCTGGGTGAAATCGTCCGCAACATCTTAATCGACTTCACCAAGAAGGGATTCCTCTTCCGAGGGCAGATCTCTGAGACGCTGAA GACCCGGGGCATCTTTGAGACCAAGTTTCTCTCTCAGATCGAGAGTGACCGATTAGCACTGCTCCAGGTCCGGGCTATCCTCCAGCAGCTAGGTCTGAAT AGCACCTGCGATGACAGTATCCTCGTCAAGACAGTGTGCGGGGTGGTGTCCAGGAGGGCCGCACAGCTGTGTGGCGCAGGCATGGCTGCGGTTGTGGATA AGATCCGCGAGAACAGAGGACTGGACCGTCTGAATGTGACTGTGGGAGTGGACGGGACACTCTACAAGCTTCATCCACACTTCTCCAGAATCATGCACCA GACGGTGAAGGAACTGTCACCAAAATGTAACGTGTCCTTCCTCCTGTCTGAGGATGGCAGCGGCAAGGGGGCCGCCCTCATCACGGCCGTGGGCGTGCGG TTACGCACAGAGGCAAGCAGCTAAGAGTCCGGGATCCCCAGCCTACTGCCTCTCCAGCACTTCTCTCTTCAAGCGGCGACCCCCTACCCTCCCAGCGAGT TGCGCTGGGAGACGCTGGCGCCAGGGCCTGCCGGCGCGGGGAGGAAAGCAAAATCCAACTAATGGTATATATTGTAGGGTACAGAATAGAGCGTGTGCTG TTGATAATATCTCTCACCCGGATCCCTCCTCACTTGCCCTGCCACTTTGCATGGTTTGATTTTGACCTGGTCCCCCACGTGTGAAGTGTAGTGGCATCCA TTTCTAATGTATGCATTCATCCAACAGAGTTATTTATTGGCTGGAGATGGAAAATCACACCACCTGACAGGCCTTCTGGGCCTCCAAAGCCCATCCTTGG GGTTCCCCCTCCCTGTGTGAAATGTATTATCACCAGCAGACACTGCCGGGCCTCCCTCCCGGGGGCACTGCCTGAAGGCGAGTGTGGGCATAGCATTAGC TGCTTCCTCCCCTCCTGGCACCCACTGTGGCCTGGCATCGCATCGTGGTGTGTCAATGCCACAAAATCGTGTGTCCGTGGAACCAGTCCTAGCCGCGTGT GACAGTCTTGCATTCTGTTTGTCTCGTGGGGGGAGGTGGACAGTCCTGCGGAAATGTGTCTTGTCTCCATTTGGATAAAAGGAACCAACCAACAAACAAT GCCATCACTGGAATTTCCCACCGCTTTGTGAGCCGTGTCGTATGACCTAGTAAACTTTGTACCAATTC

refseq_HK1.F3 (forward primer)
refseq_HK1.R3 (reverse primer)
Single exon skipping

Frame 0

KTSILLCLDRPAPETSWAMEG*LLKV**ARPAT MQQGLQLTN*RTVPQSIVPEKEKSPNTYPHLLCA KNPQLDCKDSVCCPFGKMRVSPNEEQAKAFKTQ LLRVEKQKKGPEVSKCPPHNGADLPARIGYSS* KTKTSSTC*K*D*QVSLCHAALR*NSHRYHDSLQ EGDEEWPLPGF*SNSHSQDVANIRKVHS*WL*K GRFHCPGSWWVFLSNSAGASES*EKPECSHGVR GL*HPREHRARQWKPAF*SCC*VPGRFHGEKEDQ GQEVTCGIHVFFSLPTIQNR*GHPDHLDKAI*S ERSGRSRCGQTA*QSHQKARGL*CQHRSCGE*H SGHHDDLWL*RPAL*SRPDHRHWHQCLLHGGTEA H*SGGRRRGEDVYQYRMGSLWRRWIIRRHPDRV *QGDRPGIPQPWKTAV*EDGQWHVLGRAGSTDP SQDGQGGPLI*RADHPGAAHPREV*HQ*CVSHRK E*GRPPQCQRNPDPPGSGAVR**LCLSPARLHH CLISLSQLGGCHTGRHLEPPA**QGHTQAADHG WCRRISLQDAPTVFPAFPQDSKALGARLRCALPP LGEWQRQGGCHGDGGGLPLGRAAPADRGDPGSF PPHQGHAAGGEEEDAGRDGAGAEEADAQQCRG* DAALLRPENSRRDREW*LLGPGSWRNQFPCAAGE NP*WEKENGGNAQQDLRHSY*NHAGHWGRAV*S HCLLHL*LLGLHGDQRPQDASGLHVLISLPADE SGRGNLDHVDKGF*GNRLRGPRCSHLTKGCDKKE RGI*PGRGGCGQRHSGHHDDLCL*GAHL*GWTH CWDRQQCLLHGGDEERGDGGGGPGADVHQHGVG GLWGQRVSG*YQDTLRQTGGRIFPKCWETKV*ED DQWYVPG*NRPQHLNRLHQEGIPLPRADL*DAE DPGHL*DQVSLSDRE*PISTAPGPGYPPAARSE *HLR*QYPRQDSVRGGVQEGRTAVWRRHGCGCG* DPREQRTGPSECDCGSGRDTLQASSTLLQNHAP DGEGTVTKM*RVLPPV*GWQRQGGRPHHGRGRA VTHRGKQLRVRDPQPTASPALLSSSGDPLPSQRV ALGDAGARACRRGEESKIQLMVYIVGYRIERVL LIISLTRIPPHLPCHFAWFDFDLVPHV*SVVAS ISNVCIHPTELFIGWRWKITPPDRPSGPPKPILG VPPPCVKCIITSRHCRASLPGALPEGECGHSIS CFLPSWHPLWPGIASWCVNATKSCVRGTSPSRV *QSCILFVSWGEVDSPAEMCLVSIWIKGTNQQTM PSLEFPTAL*AVSYDLVNFVPI

Frame 1

KHLSCCVWTGQPLKHLGQWRVNFSKFNRQDQQP CNKDFN*PTKELFPRALFLRRKRVQTPTHTCFV PRIHSWIARTVYVVLLEK*E*AQMKNKQRRSRPS C*E*KSRRKDPRSASALPTMGQICQRESATAAE KPKLHLLAESEIDKYLYAMRLSDETLIDIMTRF RKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK GDFIALDLGGSSFRILRVQVNHEKNQNVHMESE VYDTPENIVHGSGSQLFDHVAECLGDFMEKRKI KDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKA SGVEGADVVKLLNKAIKKRGDYDANIVAVVNDT VGTMMTCGYDDQHCEVGLIIGTGTNACYMEELR HIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEF DREIDRGSLNPGKQLFEKMVSGMYLGELVRLIL VKMAKEGLLFEGRITPELLTRGKFNTSDVSAIE KNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTI VSFRSANLVAATLGAILNRLRDNKGTPRLRTTV GVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFL LSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHF HLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVK MLPSFVRRTPDGTENGDFLALDLGGTNFRVLLV KIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDH IVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTS LDAGILITWTKGFKATDCVGHDVVTLLRDAIKR REEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLI VGTGSNACYMEEMKNVEMVEGDQGQMCINMEWG AFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEK MISGMYLGEIVRNILIDFTKKGFLFRGQISETLK TRGIFETKFLSQIESDRLALLQVRAILQQLGLN STCDDSILVKTVCGVVSRRAAQLCGAGMAAVVD KIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQ TVKELSPKCNVSFLLSEDGSGKGAALITAVGVR LRTEASS*ESGIPSLLPLQHFSLQAATPYPPSE LRWETLAPGPAGAGRKAKSN*WYIL*GTE*SVCC **YLSPGSLLTCPATLHGLILTWSPTCEV*WHP FLMYAFIQQSYLLAGDGKSHHLTGLLGLQSPSL GFPLPV*NVLSPADTAGPPSRGHCLKASVGIALA ASSPPGTHCGLASHRGVSMPQNRVSVEPVLAAC DSLAFCLSRGGRWTVLRKCVLSPFG*KEPTNKQ CHHWNFPPLCEPCRMT**TLYQF

Frame 2

NIYLAVFGQASP*NILGNGGLTSQSLIGKTSNH ATRTSTNQLKNCSPEHCS*EGKESKHLPTPALC QESTVGLQGQCMLSFWKNESEPK*RTSKGVQDP AVESRKAEERTRGQQVPSPQWGRSASENRLQQLK NQNFIYLLKVRLTSISMPCGSPMKLS*IS*LAS GRR*RMASPGILIQQPQSRCCQHS*GPFLMALK REISLPWILVGLPFEFCGCK*IMRKTRMFTWSPR FMTPQRTSCTAVEASFLIMLLSAWEISWRKGRS RTRSYLWDSRFLFLANNPK*MRPS*SPGQSDLK RAEWKEQMWSNCLTKPSKSEGTMMPTS*LW*MTQ WAP**PVAMTTSTVKSA*SSALAPMLATWRN*G TLIWWKETRGGCVSIQNGEPLETMDH*KTSGQS LTGR*TGDPSTLENSCLRRWSVACTWESWFD*S* SRWPRRASYLKGGSPRSCSPEGSLTPVMCQPSK RIRKASTMPKKS*PAWEWSRPMMTVSQSSTFAP LSHFAQPTWWLPHWAPS*TACVITRAHPGCGPRL VSTDLFTRRTHSIPGVSTRL*GAWCQTPMCASS SRRVAAARGLPW*RRWPTAWPSSTGR*RRPWLI STSPRTCCWR*RRGCGPRWSWG*GSRRTTMPWLR CCPPSSGELPTGPRMVTSWPWILEEPISVCCW* KSVVGKRERWKCTTRSTPFLLKSCRALGKSCLI TLSPASLTSWTTWGSKAPGCLWASRSHFPASRRV WTRES*SRGQRVLRQQTAWATM*SPY*GMR*KG ERNLTWTWWLWSTTQWAP**PVLMRSPPVRLDS LLGPAAMPATWRR*RTWRWWRGTRGRCASTWSGG PLGTTGVWMISGHTTTDWWTNIP*MLGNKGMRR *SVVCTWVKSSATS*STSPRRDSSSEGRSLRR* RPGASLRPSFSLRSRVTD*HCSRSGLSSSS*V*I APAMTVSSSRQCAGWCPGGPHSCVAQAWLRLWI RSARTEDWTV*M*LWEWTGHSTSFIHTSPESCT RR*RNCHQNVTCPSSCLRMAAARGPPSSRPWACG YAQRQAAKSPGSPAYCLSSTSLFKRRPPTLPAS CAGRRWRQGLPARGGKQNPTNGIYCRVQNRACA VDNISHPDPSSLALPLCMV*F*PGPPRVKCSGIH F*CMHSSNRVIYWLEMENHTT*QAFWASKAHPW GSPSLCEMYYHQQTLPGLPPGGTA*RRVWA*H* LLPPLLAPTVAWHRIVVCQCHKIVCPWNQS*PRV TVLHSVCLVGGGGQSCGNVSCLHLDKRNQPTNN AITGISHRFVSRVV*PSKLCTN

Sequence NM_033497

AAAACATCTATCTTGCTGTGTTTGGACAGGCCAGCCCCTGAAACATCTTGGGCAATGGAGGGTTAACTTCTCAAAGTTTAATAGGCAAGACCAGCAACCA TGCAACAAGGACTTCAACTAACCAACTAAAGAACTGTTCCCCAGAGCATTGTTCCTGAGAAGGAAAAGAGTCCAAACACCTACCCACACCTGCTTTGTGC CAAGAATCCACAGTTGGATTGCAAGGACAGTGCGTTCAAGACCCAGCTGTTGAGAGTAGAAAAGCAGAAGAAAGGACCCGAGGTCAGCAAGTGCCCTCCC CACAATGGGGCAGATCTGCCAGCGAGAATCGGCTACAGCAGCTGAAAAACCAAAACTTCATCTACTTGCTGAAAGTGAGATTGACAAGTATCTCTATGCC ATGCGGCTCTCCGATGAAACTCTCATAGATATCATGACTCGCTTCAGGAAGGAGATGAAGAATGGCCTCTCCCGGGATTTTAATCCAACAGCCACAGTCA AGATGTTGCCAACATTCGTAAGGTCCATTCCTGATGGCTCTGAAAAGGGAGATTTCATTGCCCTGGATCTTGGTGGGTCTTCCTTTCGAATTCTGCGGGT GCAAGTGAATCATGAGAAAAACCAGAATGTTCACATGGAGTCCGAGGTTTATGACACCCCAGAGAACATCGTGCACGGCAGTGGAAGCCAGCTTTTTGAT CATGTTGCTGAGTGCCTGGGAGATTTCATGGAGAAAAGGAAGATCAAGGACAAGAAGTTACCTGTGGGATTCACGTTTTCTTTTCCTTGCCAACAATCCA AAATAGATGAGGCCATCCTGATCACCTGGACAAAGCGATTTAAAGCGAGCGGAGTGGAAGGAGCAGATGTGGTCAAACTGCTTAACAAAGCCATCAAAAA GCGAGGGGACTATGATGCCAACATCGTAGCTGTGGTGAATGACACAGTGGGCACCATGATGACCTGTGGCTATGACGACCAGCACTGTGAAGTCGGCCTG ATCATCGGCACTGGCACCAATGCTTGCTACATGGAGGAACTGAGGCACATTGATCTGGTGGAAGGAGACGAGGGGAGGATGTGTATCAATACAGAATGGG GAGCCTTTGGAGACGATGGATCATTAGAAGACATCCGGACAGAGTTTGACAGGGAGATAGACCGGGGATCCCTCAACCCTGGAAAACAGCTGTTTGAGAA GATGGTCAGTGGCATGTACTTGGGAGAGCTGGTTCGACTGATCCTAGTCAAGATGGCCAAGGAGGGCCTCTTATTTGAAGGGCGGATCACCCCGGAGCTG CTCACCCGAGGGAAGTTTAACACCAGTGATGTGTCAGCCATCGAAAAGAATAAGGAAGGCCTCCACAATGCCAAAGAAATCCTGACCCGCCTGGGAGTGG AGCCGTCCGATGATGACTGTGTCTCAGTCCAGCACGTTTGCACCATTGTCTCATTTCGCTCAGCCAACTTGGTGGCTGCCACACTGGGCGCCATCTTGAA CCGCCTGCGTGATAACAAGGGCACACCCAGGCTGCGGACCACGGTTGGTGTCGACGGATCTCTTTACAAGACGCACCCACAGTATTCCCGGCGTTTCCAC AAGACTCTAAGGCGCTTGGTGCCAGACTCCGATGTGCGCTTCCTCCTCTCGGAGAGTGGCAGCGGCAAGGGGGCTGCCATGGTGACGGCGGTGGCCTACC GCTTGGCCGAGCAGCACCGGCAGATAGAGGAGACCCTGGCTCATTTCCACCTCACCAAGGACATGCTGCTGGAGGTGAAGAAGAGGATGCGGGCCGAGAT GGAGCTGGGGCTGAGGAAGCAGACGCACAACAATGCCGTGGTTAAGATGCTGCCCTCCTTCGTCCGGAGAACTCCCGACGGGACCGAGAATGGTGACTTC TTGGCCCTGGATCTTGGAGGAACCAATTTCCGTGTGCTGCTGGTGAAAATCCGTAGTGGGAAAAAGAGAACGGTGGAAATGCACAACAAGATCTACGCCA TTCCTATTGAAATCATGCAGGGCACTGGGGAAGAGCTGTTTGATCACATTGTCTCCTGCATCTCTGACTTCTTGGACTACATGGGGATCAAAGGCCCCAG GATGCCTCTGGGCTTCACGTTCTCATTTCCCTGCCAGCAGACGAGTCTGGACGCGGGAATCTTGATCACGTGGACAAAGGGTTTTAAGGCAACAGACTGC GTGGGCCACGATGTAGTCACCTTACTAAGGGATGCGATAAAAAGGAGAGAGGAATTTGACCTGGACGTGGTGGCTGTGGTCAACGACACAGTGGGCACCA TGATGACCTGTGCTTATGAGGAGCCCACCTGTGAGGTTGGACTCATTGTTGGGACCGGCAGCAATGCCTGCTACATGGAGGAGATGAAGAACGTGGAGAT GGTGGAGGGGGACCAGGGGCAGATGTGCATCAACATGGAGTGGGGGGCCTTTGGGGACAACGGGTGTCTGGATGATATCAGGACACACTACGACAGACTG GTGGACGAATATTCCCTAAATGCTGGGAAACAAAGGTATGAGAAGATGATCAGTGGTATGTACCTGGGTGAAATCGTCCGCAACATCTTAATCGACTTCA CCAAGAAGGGATTCCTCTTCCGAGGGCAGATCTCTGAGACGCTGAAGACCCGGGGCATCTTTGAGACCAAGTTTCTCTCTCAGATCGAGAGTGACCGATT AGCACTGCTCCAGGTCCGGGCTATCCTCCAGCAGCTAGGTCTGAATAGCACCTGCGATGACAGTATCCTCGTCAAGACAGTGTGCGGGGTGGTGTCCAGG AGGGCCGCACAGCTGTGTGGCGCAGGCATGGCTGCGGTTGTGGATAAGATCCGCGAGAACAGAGGACTGGACCGTCTGAATGTGACTGTGGGAGTGGACG GGACACTCTACAAGCTTCATCCACACTTCTCCAGAATCATGCACCAGACGGTGAAGGAACTGTCACCAAAATGTAACGTGTCCTTCCTCCTGTCTGAGGA TGGCAGCGGCAAGGGGGCCGCCCTCATCACGGCCGTGGGCGTGCGGTTACGCACAGAGGCAAGCAGCTAAGAGTCCGGGATCCCCAGCCTACTGCCTCTC CAGCACTTCTCTCTTCAAGCGGCGACCCCCTACCCTCCCAGCGAGTTGCGCTGGGAGACGCTGGCGCCAGGGCCTGCCGGCGCGGGGAGGAAAGCAAAAT CCAACTAATGGTATATATTGTAGGGTACAGAATAGAGCGTGTGCTGTTGATAATATCTCTCACCCGGATCCCTCCTCACTTGCCCTGCCACTTTGCATGG TTTGATTTTGACCTGGTCCCCCACGTGTGAAGTGTAGTGGCATCCATTTCTAATGTATGCATTCATCCAACAGAGTTATTTATTGGCTGGAGATGGAAAA TCACACCACCTGACAGGCCTTCTGGGCCTCCAAAGCCCATCCTTGGGGTTCCCCCTCCCTGTGTGAAATGTATTATCACCAGCAGACACTGCCGGGCCTC CCTCCCGGGGGCACTGCCTGAAGGCGAGTGTGGGCATAGCATTAGCTGCTTCCTCCCCTCCTGGCACCCACTGTGGCCTGGCATCGCATCGTGGTGTGTC AATGCCACAAAATCGTGTGTCCGTGGAACCAGTCCTAGCCGCGTGTGACAGTCTTGCATTCTGTTTGTCTCGTGGGGGGAGGTGGACAGTCCTGCGGAAA TGTGTCTTGTCTCCATTTGGATAAAAGGAACCAACCAACAAACAATGCCATCACTGGAATTTCCCACCGCTTTGTGAGCCGTGTCGTATGACCTAGTAAA CTTTGTACCAATTC

refseq_HK1.F3 (forward primer)
refseq_HK1.R3 (reverse primer)
Single exon skipping

Frame 0

KTSILLCLDRPAPETSWAMEG*LLKV**ARPAT MQQGLQLTN*RTVPQSIVPEKEKSPNTYPHLLCA KNPQLDCKDSAFKTQLLRVEKQKKGPEVSKCPP HNGADLPARIGYSS*KTKTSSTC*K*D*QVSLC HAALR*NSHRYHDSLQEGDEEWPLPGF*SNSHSQ DVANIRKVHS*WL*KGRFHCPGSWWVFLSNSAG ASES*EKPECSHGVRGL*HPREHRARQWKPAF* SCC*VPGRFHGEKEDQGQEVTCGIHVFFSLPTIQ NR*GHPDHLDKAI*SERSGRSRCGQTA*QSHQK ARGL*CQHRSCGE*HSGHHDDLWL*RPAL*SRP DHRHWHQCLLHGGTEAH*SGGRRRGEDVYQYRMG SLWRRWIIRRHPDRV*QGDRPGIPQPWKTAV*E DGQWHVLGRAGSTDPSQDGQGGPLI*RADHPGA AHPREV*HQ*CVSHRKE*GRPPQCQRNPDPPGSG AVR**LCLSPARLHHCLISLSQLGGCHTGRHLE PPA**QGHTQAADHGWCRRISLQDAPTVFPAFP QDSKALGARLRCALPPLGEWQRQGGCHGDGGGLP LGRAAPADRGDPGSFPPHQGHAAGGEEEDAGRD GAGAEEADAQQCRG*DAALLRPENSRRDREW*L LGPGSWRNQFPCAAGENP*WEKENGGNAQQDLRH SY*NHAGHWGRAV*SHCLLHL*LLGLHGDQRPQ DASGLHVLISLPADESGRGNLDHVDKGF*GNRL RGPRCSHLTKGCDKKERGI*PGRGGCGQRHSGHH DDLCL*GAHL*GWTHCWDRQQCLLHGGDEERGD GGGGPGADVHQHGVGGLWGQRVSG*YQDTLRQT GGRIFPKCWETKV*EDDQWYVPG*NRPQHLNRLH QEGIPLPRADL*DAEDPGHL*DQVSLSDRE*PI STAPGPGYPPAARSE*HLR*QYPRQDSVRGGVQ EGRTAVWRRHGCGCG*DPREQRTGPSECDCGSGR DTLQASSTLLQNHAPDGEGTVTKM*RVLPPV*G WQRQGGRPHHGRGRAVTHRGKQLRVRDPQPTAS PALLSSSGDPLPSQRVALGDAGARACRRGEESKI QLMVYIVGYRIERVLLIISLTRIPPHLPCHFAW FDFDLVPHV*SVVASISNVCIHPTELFIGWRWK ITPPDRPSGPPKPILGVPPPCVKCIITSRHCRAS LPGALPEGECGHSISCFLPSWHPLWPGIASWCV NATKSCVRGTSPSRV*QSCILFVSWGEVDSPAE MCLVSIWIKGTNQQTMPSLEFPTAL*AVSYDLVN FVPI

Frame 1

KHLSCCVWTGQPLKHLGQWRVNFSKFNRQDQQP CNKDFN*PTKELFPRALFLRRKRVQTPTHTCFV PRIHSWIARTVRSRPSC*E*KSRRKDPRSASALP TMGQICQRESATAAEKPKLHLLAESEIDKYLYA MRLSDETLIDIMTRFRKEMKNGLSRDFNPTATV KMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRV QVNHEKNQNVHMESEVYDTPENIVHGSGSQLFD HVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQS KIDEAILITWTKRFKASGVEGADVVKLLNKAIKK RGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGL IIGTGTNACYMEELRHIDLVEGDEGRMCINTEW GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEK MVSGMYLGELVRLILVKMAKEGLLFEGRITPEL LTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGV EPSDDDCVSVQHVCTIVSFRSANLVAATLGAILN RLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFH KTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAY RLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEM ELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDF LALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPR MPLGFTFSFPCQQTSLDAGILITWTKGFKATDC VGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGT MMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEM VEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRL VDEYSLNAGKQRYEKMISGMYLGEIVRNILIDF TKKGFLFRGQISETLKTRGIFETKFLSQIESDRL ALLQVRAILQQLGLNSTCDDSILVKTVCGVVSR RAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSED GSGKGAALITAVGVRLRTEASS*ESGIPSLLPL QHFSLQAATPYPPSELRWETLAPGPAGAGRKAK SN*WYIL*GTE*SVCC**YLSPGSLLTCPATLHG LILTWSPTCEV*WHPFLMYAFIQQSYLLAGDGK SHHLTGLLGLQSPSLGFPLPV*NVLSPADTAGP PSRGHCLKASVGIALAASSPPGTHCGLASHRGVS MPQNRVSVEPVLAACDSLAFCLSRGGRWTVLRK CVLSPFG*KEPTNKQCHHWNFPPLCEPCRMT** TLYQF

Frame 2

NIYLAVFGQASP*NILGNGGLTSQSLIGKTSNH ATRTSTNQLKNCSPEHCS*EGKESKHLPTPALC QESTVGLQGQCVQDPAVESRKAEERTRGQQVPS PQWGRSASENRLQQLKNQNFIYLLKVRLTSISMP CGSPMKLS*IS*LASGRR*RMASPGILIQQPQS RCCQHS*GPFLMALKREISLPWILVGLPFEFCG CK*IMRKTRMFTWSPRFMTPQRTSCTAVEASFLI MLLSAWEISWRKGRSRTRSYLWDSRFLFLANNP K*MRPS*SPGQSDLKRAEWKEQMWSNCLTKPSK SEGTMMPTS*LW*MTQWAP**PVAMTTSTVKSA* SSALAPMLATWRN*GTLIWWKETRGGCVSIQNG EPLETMDH*KTSGQSLTGR*TGDPSTLENSCLR RWSVACTWESWFD*S*SRWPRRASYLKGGSPRSC SPEGSLTPVMCQPSKRIRKASTMPKKS*PAWEW SRPMMTVSQSSTFAPLSHFAQPTWWLPHWAPS* TACVITRAHPGCGPRLVSTDLFTRRTHSIPGVST RL*GAWCQTPMCASSSRRVAAARGLPW*RRWPT AWPSSTGR*RRPWLISTSPRTCCWR*RRGCGPR WSWG*GSRRTTMPWLRCCPPSSGELPTGPRMVTS WPWILEEPISVCCW*KSVVGKRERWKCTTRSTP FLLKSCRALGKSCLITLSPASLTSWTTWGSKAP GCLWASRSHFPASRRVWTRES*SRGQRVLRQQTA WATM*SPY*GMR*KGERNLTWTWWLWSTTQWAP **PVLMRSPPVRLDSLLGPAAMPATWRR*RTWR WWRGTRGRCASTWSGGPLGTTGVWMISGHTTTDW WTNIP*MLGNKGMRR*SVVCTWVKSSATS*STS PRRDSSSEGRSLRR*RPGASLRPSFSLRSRVTD *HCSRSGLSSSS*V*IAPAMTVSSSRQCAGWCPG GPHSCVAQAWLRLWIRSARTEDWTV*M*LWEWT GHSTSFIHTSPESCTRR*RNCHQNVTCPSSCLR MAAARGPPSSRPWACGYAQRQAAKSPGSPAYCLS STSLFKRRPPTLPASCAGRRWRQGLPARGGKQN PTNGIYCRVQNRACAVDNISHPDPSSLALPLCM V*F*PGPPRVKCSGIHF*CMHSSNRVIYWLEMEN HTT*QAFWASKAHPWGSPSLCEMYYHQQTLPGL PPGGTA*RRVWA*H*LLPPLLAPTVAWHRIVVC QCHKIVCPWNQS*PRVTVLHSVCLVGGGGQSCGN VSCLHLDKRNQPTNNAITGISHRFVSRVV*PSK LCTN

Sequence NM_033500

AAAACATCTATCTTGCTGTGTTTGGACAGGCCAGCCCCTGAAACATCTTGGGCAATGGAGGGTTAACTTCTCAAAGTTTAATAGGCAAGACCAGCAACCA TGCAACAAGGACTTCAACTAACCAACTAAAGAACTGTTCCCCAGAGCATTGTTCCTGAGAAGGAAAAGAGTCCAAACACCTACCCACACCTGCTTTGTGC CAAGAATCCACAGTTGGATTGCAAGGACAGTGTATGTTGTCCTTTTGGAAAAATGAGAGTGAGCCCAAATGAAGAACAAGCAAAGGCGTTCAAGACCCAG CTGTTGAGAGTAGAAAAGCAGAAGAAAGGACCCGAGGTCAGCAAGTGCCCTCCCCACAATGGGGCAGATCTGCCAGCGAGAATCGGCTACAGCAGCTGAA AAACCAAAACTTCATCTACTTGCTGAAAGTGAGCATTGTTGATGCTCTTGAGAGCATCAGCCAGGACATTAATGTGCACCACTGTGGTGGCGTGGAAAGA TGGCAAAAAGAGCCCTGCATGATTTTATTGACAAGTATCTCTATGCCATGCGGCTCTCCGATGAAACTCTCATAGATATCATGACTCGCTTCAGGAAGGA GATGAAGAATGGCCTCTCCCGGGATTTTAATCCAACAGCCACAGTCAAGATGTTGCCAACATTCGTAAGGTCCATTCCTGATGGCTCTGAAAAGGGAGAT TTCATTGCCCTGGATCTTGGTGGGTCTTCCTTTCGAATTCTGCGGGTGCAAGTGAATCATGAGAAAAACCAGAATGTTCACATGGAGTCCGAGGTTTATG ACACCCCAGAGAACATCGTGCACGGCAGTGGAAGCCAGCTTTTTGATCATGTTGCTGAGTGCCTGGGAGATTTCATGGAGAAAAGGAAGATCAAGGACAA GAAGTTACCTGTGGGATTCACGTTTTCTTTTCCTTGCCAACAATCCAAAATAGATGAGGCCATCCTGATCACCTGGACAAAGCGATTTAAAGCGAGCGGA GTGGAAGGAGCAGATGTGGTCAAACTGCTTAACAAAGCCATCAAAAAGCGAGGGGACTATGATGCCAACATCGTAGCTGTGGTGAATGACACAGTGGGCA CCATGATGACCTGTGGCTATGACGACCAGCACTGTGAAGTCGGCCTGATCATCGGCACTGGCACCAATGCTTGCTACATGGAGGAACTGAGGCACATTGA TCTGGTGGAAGGAGACGAGGGGAGGATGTGTATCAATACAGAATGGGGAGCCTTTGGAGACGATGGATCATTAGAAGACATCCGGACAGAGTTTGACAGG GAGATAGACCGGGGATCCCTCAACCCTGGAAAACAGCTGTTTGAGAAGATGGTCAGTGGCATGTACTTGGGAGAGCTGGTTCGACTGATCCTAGTCAAGA TGGCCAAGGAGGGCCTCTTATTTGAAGGGCGGATCACCCCGGAGCTGCTCACCCGAGGGAAGTTTAACACCAGTGATGTGTCAGCCATCGAAAAGAATAA GGAAGGCCTCCACAATGCCAAAGAAATCCTGACCCGCCTGGGAGTGGAGCCGTCCGATGATGACTGTGTCTCAGTCCAGCACGTTTGCACCATTGTCTCA TTTCGCTCAGCCAACTTGGTGGCTGCCACACTGGGCGCCATCTTGAACCGCCTGCGTGATAACAAGGGCACACCCAGGCTGCGGACCACGGTTGGTGTCG ACGGATCTCTTTACAAGACGCACCCACAGTATTCCCGGCGTTTCCACAAGACTCTAAGGCGCTTGGTGCCAGACTCCGATGTGCGCTTCCTCCTCTCGGA GAGTGGCAGCGGCAAGGGGGCTGCCATGGTGACGGCGGTGGCCTACCGCTTGGCCGAGCAGCACCGGCAGATAGAGGAGACCCTGGCTCATTTCCACCTC ACCAAGGACATGCTGCTGGAGGTGAAGAAGAGGATGCGGGCCGAGATGGAGCTGGGGCTGAGGAAGCAGACGCACAACAATGCCGTGGTTAAGATGCTGC CCTCCTTCGTCCGGAGAACTCCCGACGGGACCGAGAATGGTGACTTCTTGGCCCTGGATCTTGGAGGAACCAATTTCCGTGTGCTGCTGGTGAAAATCCG TAGTGGGAAAAAGAGAACGGTGGAAATGCACAACAAGATCTACGCCATTCCTATTGAAATCATGCAGGGCACTGGGGAAGAGCTGTTTGATCACATTGTC TCCTGCATCTCTGACTTCTTGGACTACATGGGGATCAAAGGCCCCAGGATGCCTCTGGGCTTCACGTTCTCATTTCCCTGCCAGCAGACGAGTCTGGACG CGGGAATCTTGATCACGTGGACAAAGGGTTTTAAGGCAACAGACTGCGTGGGCCACGATGTAGTCACCTTACTAAGGGATGCGATAAAAAGGAGAGAGGA ATTTGACCTGGACGTGGTGGCTGTGGTCAACGACACAGTGGGCACCATGATGACCTGTGCTTATGAGGAGCCCACCTGTGAGGTTGGACTCATTGTTGGG ACCGGCAGCAATGCCTGCTACATGGAGGAGATGAAGAACGTGGAGATGGTGGAGGGGGACCAGGGGCAGATGTGCATCAACATGGAGTGGGGGGCCTTTG GGGACAACGGGTGTCTGGATGATATCAGGACACACTACGACAGACTGGTGGACGAATATTCCCTAAATGCTGGGAAACAAAGGTATGAGAAGATGATCAG TGGTATGTACCTGGGTGAAATCGTCCGCAACATCTTAATCGACTTCACCAAGAAGGGATTCCTCTTCCGAGGGCAGATCTCTGAGACGCTGAAGACCCGG GGCATCTTTGAGACCAAGTTTCTCTCTCAGATCGAGAGTGACCGATTAGCACTGCTCCAGGTCCGGGCTATCCTCCAGCAGCTAGGTCTGAATAGCACCT GCGATGACAGTATCCTCGTCAAGACAGTGTGCGGGGTGGTGTCCAGGAGGGCCGCACAGCTGTGTGGCGCAGGCATGGCTGCGGTTGTGGATAAGATCCG CGAGAACAGAGGACTGGACCGTCTGAATGTGACTGTGGGAGTGGACGGGACACTCTACAAGCTTCATCCACACTTCTCCAGAATCATGCACCAGACGGTG AAGGAACTGTCACCAAAATGTAACGTGTCCTTCCTCCTGTCTGAGGATGGCAGCGGCAAGGGGGCCGCCCTCATCACGGCCGTGGGCGTGCGGTTACGCA CAGAGGCAAGCAGCTAAGAGTCCGGGATCCCCAGCCTACTGCCTCTCCAGCACTTCTCTCTTCAAGCGGCGACCCCCTACCCTCCCAGCGAGTTGCGCTG GGAGACGCTGGCGCCAGGGCCTGCCGGCGCGGGGAGGAAAGCAAAATCCAACTAATGGTATATATTGTAGGGTACAGAATAGAGCGTGTGCTGTTGATAA TATCTCTCACCCGGATCCCTCCTCACTTGCCCTGCCACTTTGCATGGTTTGATTTTGACCTGGTCCCCCACGTGTGAAGTGTAGTGGCATCCATTTCTAA TGTATGCATTCATCCAACAGAGTTATTTATTGGCTGGAGATGGAAAATCACACCACCTGACAGGCCTTCTGGGCCTCCAAAGCCCATCCTTGGGGTTCCC CCTCCCTGTGTGAAATGTATTATCACCAGCAGACACTGCCGGGCCTCCCTCCCGGGGGCACTGCCTGAAGGCGAGTGTGGGCATAGCATTAGCTGCTTCC TCCCCTCCTGGCACCCACTGTGGCCTGGCATCGCATCGTGGTGTGTCAATGCCACAAAATCGTGTGTCCGTGGAACCAGTCCTAGCCGCGTGTGACAGTC TTGCATTCTGTTTGTCTCGTGGGGGGAGGTGGACAGTCCTGCGGAAATGTGTCTTGTCTCCATTTGGATAAAAGGAACCAACCAACAAACAATGCCATCA CTGGAATTTCCCACCGCTTTGTGAGCCGTGTCGTATGACCTAGTAAACTTTGTACCAATTC

refseq_HK1.F3 (forward primer)
refseq_HK1.R3 (reverse primer)
Single exon skipping

Frame 0

KTSILLCLDRPAPETSWAMEG*LLKV**ARPAT MQQGLQLTN*RTVPQSIVPEKEKSPNTYPHLLCA KNPQLDCKDSVCCPFGKMRVSPNEEQAKAFKTQ LLRVEKQKKGPEVSKCPPHNGADLPARIGYSS* KTKTSSTC*K*ALLMLLRASARTLMCTTVVAWKD GKKSPA*FY*QVSLCHAALR*NSHRYHDSLQEG DEEWPLPGF*SNSHSQDVANIRKVHS*WL*KGR FHCPGSWWVFLSNSAGASES*EKPECSHGVRGL* HPREHRARQWKPAF*SCC*VPGRFHGEKEDQGQ EVTCGIHVFFSLPTIQNR*GHPDHLDKAI*SER SGRSRCGQTA*QSHQKARGL*CQHRSCGE*HSGH HDDLWL*RPAL*SRPDHRHWHQCLLHGGTEAH* SGGRRRGEDVYQYRMGSLWRRWIIRRHPDRV*Q GDRPGIPQPWKTAV*EDGQWHVLGRAGSTDPSQD GQGGPLI*RADHPGAAHPREV*HQ*CVSHRKE* GRPPQCQRNPDPPGSGAVR**LCLSPARLHHCL ISLSQLGGCHTGRHLEPPA**QGHTQAADHGWCR RISLQDAPTVFPAFPQDSKALGARLRCALPPLG EWQRQGGCHGDGGGLPLGRAAPADRGDPGSFPP HQGHAAGGEEEDAGRDGAGAEEADAQQCRG*DAA LLRPENSRRDREW*LLGPGSWRNQFPCAAGENP *WEKENGGNAQQDLRHSY*NHAGHWGRAV*SHC LLHL*LLGLHGDQRPQDASGLHVLISLPADESGR GNLDHVDKGF*GNRLRGPRCSHLTKGCDKKERG I*PGRGGCGQRHSGHHDDLCL*GAHL*GWTHCW DRQQCLLHGGDEERGDGGGGPGADVHQHGVGGLW GQRVSG*YQDTLRQTGGRIFPKCWETKV*EDDQ WYVPG*NRPQHLNRLHQEGIPLPRADL*DAEDP GHL*DQVSLSDRE*PISTAPGPGYPPAARSE*HL R*QYPRQDSVRGGVQEGRTAVWRRHGCGCG*DP REQRTGPSECDCGSGRDTLQASSTLLQNHAPDG EGTVTKM*RVLPPV*GWQRQGGRPHHGRGRAVTH RGKQLRVRDPQPTASPALLSSSGDPLPSQRVAL GDAGARACRRGEESKIQLMVYIVGYRIERVLLI ISLTRIPPHLPCHFAWFDFDLVPHV*SVVASISN VCIHPTELFIGWRWKITPPDRPSGPPKPILGVP PPCVKCIITSRHCRASLPGALPEGECGHSISCF LPSWHPLWPGIASWCVNATKSCVRGTSPSRV*QS CILFVSWGEVDSPAEMCLVSIWIKGTNQQTMPS LEFPTAL*AVSYDLVNFVPI

Frame 1

KHLSCCVWTGQPLKHLGQWRVNFSKFNRQDQQP CNKDFN*PTKELFPRALFLRRKRVQTPTHTCFV PRIHSWIARTVYVVLLEK*E*AQMKNKQRRSRPS C*E*KSRRKDPRSASALPTMGQICQRESATAAE KPKLHLLAESEHC*CS*EHQPGH*CAPLWWRGK MAKRALHDFIDKYLYAMRLSDETLIDIMTRFRKE MKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGD FIALDLGGSSFRILRVQVNHEKNQNVHMESEVY DTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDK KLPVGFTFSFPCQQSKIDEAILITWTKRFKASG VEGADVVKLLNKAIKKRGDYDANIVAVVNDTVG TMMTCGYDDQHCEVGLIIGTGTNACYMEELRHID LVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDR EIDRGSLNPGKQLFEKMVSGMYLGELVRLILVK MAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNK EGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVS FRSANLVAATLGAILNRLRDNKGTPRLRTTVGV DGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSE SGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHL TKDMLLEVKKRMRAEMELGLRKQTHNNAVVKML PSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIR SGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIV SCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLD AGILITWTKGFKATDCVGHDVVTLLRDAIKRREE FDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVG TGSNACYMEEMKNVEMVEGDQGQMCINMEWGAF GDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMIS GMYLGEIVRNILIDFTKKGFLFRGQISETLKTR GIFETKFLSQIESDRLALLQVRAILQQLGLNST CDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIR ENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTV KELSPKCNVSFLLSEDGSGKGAALITAVGVRLR TEASS*ESGIPSLLPLQHFSLQAATPYPPSELRW ETLAPGPAGAGRKAKSN*WYIL*GTE*SVCC** YLSPGSLLTCPATLHGLILTWSPTCEV*WHPFL MYAFIQQSYLLAGDGKSHHLTGLLGLQSPSLGFP LPV*NVLSPADTAGPPSRGHCLKASVGIALAAS SPPGTHCGLASHRGVSMPQNRVSVEPVLAACDS LAFCLSRGGRWTVLRKCVLSPFG*KEPTNKQCHH WNFPPLCEPCRMT**TLYQF

Frame 2

NIYLAVFGQASP*NILGNGGLTSQSLIGKTSNH ATRTSTNQLKNCSPEHCS*EGKESKHLPTPALC QESTVGLQGQCMLSFWKNESEPK*RTSKGVQDP AVESRKAEERTRGQQVPSPQWGRSASENRLQQLK NQNFIYLLKVSIVDALESISQDINVHHCGGVER WQKEPCMILLTSISMPCGSPMKLS*IS*LASGR R*RMASPGILIQQPQSRCCQHS*GPFLMALKREI SLPWILVGLPFEFCGCK*IMRKTRMFTWSPRFM TPQRTSCTAVEASFLIMLLSAWEISWRKGRSRT RSYLWDSRFLFLANNPK*MRPS*SPGQSDLKRAE WKEQMWSNCLTKPSKSEGTMMPTS*LW*MTQWA P**PVAMTTSTVKSA*SSALAPMLATWRN*GTL IWWKETRGGCVSIQNGEPLETMDH*KTSGQSLTG R*TGDPSTLENSCLRRWSVACTWESWFD*S*SR WPRRASYLKGGSPRSCSPEGSLTPVMCQPSKRI RKASTMPKKS*PAWEWSRPMMTVSQSSTFAPLSH FAQPTWWLPHWAPS*TACVITRAHPGCGPRLVS TDLFTRRTHSIPGVSTRL*GAWCQTPMCASSSR RVAAARGLPW*RRWPTAWPSSTGR*RRPWLISTS PRTCCWR*RRGCGPRWSWG*GSRRTTMPWLRCC PPSSGELPTGPRMVTSWPWILEEPISVCCW*KS VVGKRERWKCTTRSTPFLLKSCRALGKSCLITLS PASLTSWTTWGSKAPGCLWASRSHFPASRRVWT RES*SRGQRVLRQQTAWATM*SPY*GMR*KGER NLTWTWWLWSTTQWAP**PVLMRSPPVRLDSLLG PAAMPATWRR*RTWRWWRGTRGRCASTWSGGPL GTTGVWMISGHTTTDWWTNIP*MLGNKGMRR*S VVCTWVKSSATS*STSPRRDSSSEGRSLRR*RPG ASLRPSFSLRSRVTD*HCSRSGLSSSS*V*IAP AMTVSSSRQCAGWCPGGPHSCVAQAWLRLWIRS ARTEDWTV*M*LWEWTGHSTSFIHTSPESCTRR* RNCHQNVTCPSSCLRMAAARGPPSSRPWACGYA QRQAAKSPGSPAYCLSSTSLFKRRPPTLPASCA GRRWRQGLPARGGKQNPTNGIYCRVQNRACAVDN ISHPDPSSLALPLCMV*F*PGPPRVKCSGIHF* CMHSSNRVIYWLEMENHTT*QAFWASKAHPWGS PSLCEMYYHQQTLPGLPPGGTA*RRVWA*H*LLP PLLAPTVAWHRIVVCQCHKIVCPWNQS*PRVTV LHSVCLVGGGGQSCGNVSCLHLDKRNQPTNNAI TGISHRFVSRVV*PSKLCTN