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Sequences

Sequence NM_194301

AGGGAGAGAGTTGTGCTCCTGCCGCCGAGAGCTCCACCTTCGTGGCTCTGGGTCCGGGGCCCCGGCCTGTGGCGGCGAGCGGCGGCCGCTGGAGACGAGC GGCGGCGGCAGGCGGCCAGCCCGGGTCTGCCTCGCTCCGTGCAGGGCCGGGAGAGGGATCCGCCATATTGGAGCTGGGGCCGAAGGTGCCTTGGAGCCGC GGCGCGAGGCGGGTGGAGGTGGCGGCCCTGGCCTGGATCGGGAAGGAGTCGGCTCTGCCCTGGCCCGCAAGGCTGGGGAGCTAATGAGCCTCTCTGGCTA GTCTCCTCCCCGTCCACTCCCTCCACTTTCTGCCGCCGGGACCCGGCTGGGAGCCGGCTGTGGCAGTGGCAGTGGCAGTGGCAGCGACAGGATGTTCTCC AAGAAGCCGCACGGGGACGTGAAGAAGTCCACCCAGAAGGTGCTAGACACCAAGAAGGACGCACTGACTCGCCTCAAGCACCTGCGCATCGTCATCGAGA ATGCAGAATCTATTGATCTTAAACAGTTTTTCGACCAACATTTTTCACATATATACTATGTGTTCTTTGAAAATTTTGTGACTATTGAAGCTAGTCTTAA ACAGAAAGGTCACAAGTCTCAAAGAGAGGAATTGGATGCTATACTTTTTATTTTTGAGAAAATTTTACAACTTCTTCCAGAAAGAATTCATCAGCGATGG CAGTTTCATAGTATTGGATTGATTTTAAAGAAGCTACTTCACACAGGAAACTCCTTAAAGATTAGGCGGGAAGGTGTTCGTCTTTTCTTACTATGGTTGC AAGCTCTTCAGAATAACTGTAGCAAAGAACAGCTCTGGATGTTTTCATGCTTAATCCCTGGATTTTCAGCACCACAGTCTGAACATGGACCTCGAACTTT AGATAATCTCATTAATCCTCCACTCAACCTTCAAGAAACTCAAGTCACTATAGAAGAAATCACTCCTCTTGTCCCCCCACAATCAGGAGATAAAGGGCAA GAAGATCTCACAAGCTATTTTCTTGAAGCACTTCTAAAATACATAGTCATTCAGGTAAAAAGTTTAGAATGGAAGAACAAAGAAAACCAAGAAAGGGGAT TTTCATTTTTGTTTTCACATTTTAAGAAATATTACTTGCCTTATATTTTTCCAAACATCTGTAAGGAAAACAGTTTATATCATCCTATACTTGACATCCC GCAGATGAGACCAAAGCCACATTATGTCGTGATAAAGAAAGATGCTGAAACCAATGAAGCAATCTATTGTACAAAGGAGCCTTTCATTAAGGCTCGTGTT ATTGTCATTCGTTGGCTGGTTTCTTTCTGGCTGGAGCCAAAACCACATACAGGACCTCATATTCCTGGGATGGAAGGTGAAGTCTTGCCAAAGAATATTC AGAGAGCAGCTGCTAGTTTAGTATCCAGAGAAGAAAGCAAAAATGATAATGCTGATAAAACAGACAGAACTACAGAACCCGAACAGTCTCATTCCAATAC AAGCACTCTCACGGAGCGAGAACCTAGCTCATCTAGTCTCTGTAGTATTGATGAAGAACATCTCACAGACATTGAAATAGTTCGCAGAGTTTTTTCTTCT AAAAGGAGTAATGTAAACTTTGTGACAGAGATATTTCGTCAGGCATTTTTATTACCAATTTGTGAAGCAGCAGCTATGAGAAAAGTGGTAAAAGTATATC AAGAATGGATCCAACAAGAGGAAAAACCTTTGTTCATGCAAGAGCCTGAAGAAATTGTGATCACTTCTTCAGACCTCCCTTGCATTGAAAATGTCACAGA CCATGATATTTCAATGGAAGAAGGAGAAAAAAGAGAAGAGGAAAATGGGACCAATACTGCTGATCATGTTCGAAATTCCAGTTGGGCAAAAAACGGCTCC TACCAAGGTGCTCTTCATAACGCCTCTGAAGAAGCCACAGAACAAAACATACGAGCTGGTACCCAGGCAGTTTTGCAGGTGTTTATTATAAACTCATCAA ATATATTTCTTCTTGAACCTGCAAATGAAATAAAAAATCTTCTGGATGAACACACAGATATGTGTAAACGCATTCTTAACATTTATCGGTACATGGTTGT ACAAGTATCAATGGACAAAAAGACTTGGGAACAGATGCTGCTTGTGTTGCTCAGAGTCACGGAATCTGTACTGAAGATGCCATCACAAGCTTTTCTACAG TTCCAAGGGAAAAAAAATATGACCTTGGCAGGTCGACTTGCAGGACCACTTTTCCAGACCCTTATAGTTGCCTGGATCAAAGCAAACCTAAATGTGTACA TCTCCCGAGAACTTTGGGATGACTTACTGTCAGTATTGTCATCGCTGACCTATTGGGAAGAGTTGGCCACTGAGTGGTCACTGACTATGGAGACATTAAC TAAAGTTTTAGCTAGGAATTTATATAGTTTGGATCTCAGTGATTTACCATTGGATAAGCTGAGTGAACAGAAACAAAAAAAGCACAAAGGGAAAGGAGTT GGACATGAATTTCAGAAAGTTTCAGTTGACAAGTCATTTTCTAGAGGATGGAGTCGTGATCAGCCTGGCCAAGCCCCAATGAGACAGAGGAGTGCAACAA CCACTGGTTCTCCAGGAACCGAAAAGGCGAGGAGTATAGTACGGCAAAAAACTGTCGATATTGATGATGCTCAAATACTTCCCCGCTCAACTAGAGTCAG ACATTTTTCACAAAGTGAAGAAACTGGAAATGAAGTTTTTGGTGCTTTGAATGAGGAGCAGCCATTGCCTCGAAGTAGCAGCACTTCTGACATCTTGGAA CCATTCACTGTTGAACGAGCCAAAGTCAATAAAGAGGACATGAGCCAAAAACTGCCTCCTCTTAATAGTGATATTGGCGGCAGCAGTGCTAATGTTCCTG ATCTGATGGATGAGTTTATAGCAGAACGACTTCGAAGTGGTAATGCCTCGACTATGACAAGAAGAGGAAGTAGTCCAGGCAGCCTGGAAATTCCCAAAGA CCTCCCTGATATTCTAAACAAGCAGAACCAGATGCGCCCTATTGATGACCCAGGTGTGCCCTCAGAATGGACTTCTCCTGCCAGTGCAGGGAGCAGTGAT CTTATCAGCTCAGATAGTCATTCGGATTCTTTCAGCGCTTTCCAATATGATGGCCGAAAATTTGACAATTTTGGCTTTGGAACCGACACTGGGGTTACGT CCTCTGCTGATGTGGATTCAGGTTCTGGCCATCATCAGAGTGCTGAAGAGCAGGAAGTGGCTAGTCTAACTACTCTTCATATAGATTCTGAAACAAGCAG TCTTAATCAGCAAGCTTTCTCTGCTGAAGTTGCAACTATTACTGGTTCAGAAAGTGCTTCCCCAGTCCACTCACCTCTGGGCTCCAGGTCACAGACTCCT TCCCCTTCTACATTGAATATAGATCACATGGAACAGAAGGATCTGCAGCTCGACGAGAAGCTCCACCACTCTGTTCTTCAGACACCAGATGATCTAGAAA TTAGTGAATTTCCATCAGAATGTTGTAGTGTGATGGCAGGAGGTACTCTGACTGGATGGCATGCTGATGTTGCTACTGTAATGTGGCGAAGAATGCTAGG CATTTTGGGAGATGTAAATTCAATCATGGATCCTGAAATACATGCTCAAGTTTTTGATTACCTCTGTGAACTTTGGCAGAATCTAGCTAAGATTAGAGAT AACCTTGGCATTTCAACTGATAACCTGACCTCCCCTTCTCCACCAGTTTTAATTCCTCCACTGAGAATTCTTACACCTTGGCTTTTTAAGGCAACCATGT TGACTGATAAATATAAACAAGGTAAATTACATGCATATAAACTTATTTGTAATACAATGAAAAGAAGACAAGATGTTTCTCCAAATAGAGATTTTCTAAC ACATTTCTACAATATAATGCATTGTGGATTACTTCATATTGACCAGGATATTGTCAATACAATCATCAAACACTGCTCACCTCAATTTTTTTCACTTGGT TTGCCTGGTGCCACAATGCTTATTATGGATTTTATTGTAGCAGCTGGTAGAGTGGCTTCTTCAGCTTTTCTCAATGCACCAAGAGTAGAAGCACAAGTTC TTCTGGGATCTTTGGTTTGCTTTCCCAACTTATATTGTGAACTGCCTTCTCTTCATCCCAACATTCCTGATGTTGCTGTGTCTCAGTTTACAGATGTTAA GGAACTTATAATCAAAACTGTATTAAGCTCGGCAAGAGATGAGCCCTCTGGTCCTGCACGATGTGTAGCACTTTGTAGTTTAGGTATTTGGATTTGTGAA GAACTAGTCCATGAGTCTCATCATCCTCAAATTAAGGAAGCTCTGAATGTGATTTGTGTTTCCTTAAAGTTTACTAATAAAACAGTAGCCCACGTAGCTT GTAACATGCTTCACATGCTGGTTCATTATGTACCTAGACTTCAGATTTACCAGCCTGATTCTCCCTTGAAAATTATTCAAATCCTAATAGCTACCATCAC CCATCTTTTACCAAGTACAGAGGCTTCATCTTATGAAATGGACAAGAGGTTGGTAGTATCTTTACTTCTCTGCCTTCTGGACTGGATCATGGCCTTACCT CTAAAGACACTGCTCCAACCATTTCATGCTACGGGAGCAGAAAGCGATAAAACAGAAAAATCTGTTCTCAATTGCATTTATAAGGTTTTACATGGGTGTG TTTATGGAGCTCAGTGTTTTAGCAATCCAAGGTATTTTCCCATGAGCCTCTCTGATTTGGCATCTGTAGATTATGATCCTTTTATGCATTTGGAAAGTCT GAAAGAGCCTGAGCCTCTGCACTCTCCTGACTCAGAACGATCTTCTAAACTCCAGCCAGTAACAGAAGTGAAAACTCAAATGCAGCATGGATTAATCTCT ATAGCAGCCCGCACTGTTATTACACATCTGGTAAATCACCTGGGCCATTATCCAATGAGCGGTGGTCCTGCTATGCTAACAAGTCAGGTGTGTGAAAATC ACGACAATCATTACAGTGAAAGTACTGAACTTTCTCCTGAACTCTTTGAGAGTCCAAATATCCAGTTCTTTGTGTTAAATAATACAACCTTAGTGTCCTG TATCCAGATCAGATCAGAAGAGAATATGCCTGGAGGAGGTTTATCTGCTGGCCTTGCATCAGCCAATTCAAATGTCAGAATCATAGTACGTGATCTCTCT GGAAAATATTCATGGGATTCTGCTATACTGTATGGCCCACCTCCTGTAAGTGGCTTGTCAGAACCTACATCTTTCATGCTTTCATTGTCTCACCAAGAGA AGCCAGAAGAGCCTCCGACATCTAATGAATGCTTAGAAGATATAACCGTAAAAGATGGACTTTCTCTCCAGTTTAAAAGATTTAGAGAAACTGTACCAAC TTGGGATACAATAAGAGATGAAGAAGATGTTCTTGATGAGCTCTTGCAGTATTTGGGTGTTACTAGTCCTGAATGCTTACAGAGAACTGGAATCTCACTT AATATTCCTGCTCCACAACCTGTGTGCATTTCTGAAAAACAAGAAAATGATGTTATTAATGCTATCCTTAAGCAACATACAGAAGAAAAAGAATTTGTTG AGAAGCACTTTAATGACTTAAACATGAAAGCTGTGGAACAAGATGAACCAATACCTCAAAAACCTCAGTCAGCATTTTATTATTGCAGATTGCTTCTTAG TATATTGGGAATGAATTCCTGGGACAAACGGAGGAGCTTTCATCTCCTGAAGAAAAATGAAAAGCTACTTAGAGAACTTAGGAACTTGGATTCAAGGCAG TGCCGAGAGACACACAAGATTGCAGTATTTTATGTTGCTGAAGGACAAGAAGACAAACACTCCATTCTCACCAATACAGGAGGAAGTCAAGCATATGAAG ATTTTGTAGCTGGTCTTGGTTGGGAGGTAAATCTTACAAACCATTGTGGTTTTATGGGAGGACTACAAAAAAACAAAAGCACTGGATTGACCACTCCATA TTTTGCTACCTCTACAGTAGAGGTAATATTTCACGTGTCAACAAGAATGCCTTCTGATTCTGATGATTCTTTGACCAAAAAATTGAGACATTTGGGAAAT GATGAAGTGCACATTGTTTGGTCAGAGCATACTAGAGACTACAGGAGAGGAATTATTCCCACAGAATTTGGTGATGTCCTTATTGTAATATATCCAATGA AAAATCACATGTTCAGTATTCAGATAATGAAAAAACCAGAGGTTCCCTTCTTTGGTCCCCTTTTTGATGGTGCTATTGTGAATGGAAAGGTTCTACCCAT TATGGTTAGAGCAACAGCTATAAATGCAAGCCGTGCTCTGAAATCTCTGATTCCATTGTATCAAAACTTCTATGAGGAGAGAGCACGATACCTGCAAACA ATTGTCCAGCACCACTTAGAACCAACAACATTTGAAGATTTTGCAGCACAGGTTTTTTCTCCAGCTCCCTACCACCATTTACCATCTGATGCCGGCTCCT ACCCAGAGATTCTACCCAGTGAAACTCCCACAGCAACGCAGGTAGATGGGGCTGACCTGGCCTCTCCAATGTCTCCTCGAACTAGCAAAAGCCGCATGTC CATGAAGCTGCGTCGTTCCTCTGGCTCAGCCAATAAATCCTAAGGAGACAAGCAGCCCAGCAGTGATCAGCAGTAGCCACCTTAGCACGAACATAGGGTT AACCCTTTCAGGCCTTCATGTCTGCCATAACATGCATGTTTCTTCCTGTACATTTATTTGAGAAAACACTGGATTTAAATAATTTTAAATAATTTGTAGC TTAATATTAAAGATTTAAGTTATTTATTGTTTCATTTTTTTTCCCACAATCCAAGCTGCCATATTTTGAGGGCAGGGGGAGTTTTATTCTACACCCTTTA CCTTCCTAGATAATTATGTCTAAGTAGTTTTATCTTTAATTTCATGGTTAACTGTGAGCCAAAATACAATTGGACAATTAGTCTCATTATTTATTGTGCC CCATTGCAACTTTATGGTTCAATAAATATATAATTTTTTACAAATGTAAAATTTTACATTTAAGCATTTGTAAAGTTACAGCAAAAGATGTACCTGTTAA TACACAGAATGTGTACAGATTATTTGTTATGACAATAAAACACTCAAAATAAATGGTCTTTAGCATCTCAAATTCCAACTGAAATCATTTTAGTATTAAC TCTTCTTCCCAAAGCAATGTCTCATTTCTTGGCTGTGCAGGTGATGCCATGTTATATCCAATAACTAGAAAAATCACTGTGCTGAACTTTTATGTTTAGC TTCCAAGTATTTTTCTAATGTTTTGCATTTCAAGTGGTATCACTGTTAAATGCCATTTGTTTTCAGATTGTGGCCTTTTATTATTGGCTGCTAGATCCTG GTGTTTCTATGTTCTTTTTTAAGCACCAAAAAGAAGATGGGGAAGAAAAGAAGGAAAATTTTCTGATATAAATATGTTGTTCAAATTATGAGTATTATTT AAAAAAGAAAAAGGAACATAACCCAGGAGTCTAAGTTAAATCTAATATTGTTAATACTGAACTTGCAGGTCCAGGTTGGTATACATTCCACCCTCTAGAA GTATTTTCTTACAGTAGATAAGCTGCTCACATTTTGTTTTGAATGGGCATCTCCTGAGGAAATGTAGCATGACATTGGTACTAACTGCATGTGTAAATAC ATCATACTGGCAAACCGTAAAATATAAATTATGTATCATCATTCATGTAGTATCTATAATTTGTAACAGTGGGGGGGAAAGATGACATGGTATTTAATAA TACAATAAAAATATTCTTATCACTTCCTATCCA

refseq_GARNL1.F1 (forward primer)
refseq_GARNL1.R1 (reverse primer)
Single exon skipping

Frame 0

RERVVLLPPRAPPSWLWVRGPGLWRRAAAAGDE RRRQAASPGLPRSVQGRERDPPYWSWGRRCLGAA ARGGWRWRPWPGSGRSRLCPGPQGWGANEPLWL VSSPSTPSTFCRRDPAGSRLWQWQWQWQRQDVL QEAARGREEVHPEGARHQEGRTDSPQAPAHRHRE CRIY*S*TVFRPTFFTYILCVL*KFCDY*S*S* TERSQVSKRGIGCYTFYF*ENFTTSSRKNSSAM AVS*YWIDFKEATSHRKLLKD*AGRCSSFLTMVA SSSE*L*QRTALDVFMLNPWIFSTTV*TWTSNF R*SH*SSTQPSRNSSHYRRNHSSCPPTIRR*RA RRSHKLFS*STSKIHSHSGKKFRMEEQRKPRKGI FIFVFTF*EILLALYFSKHL*GKQFISSYT*HP ADETKATLCRDKERC*NQ*SNLLYKGAFH*GSC YCHSLAGFFLAGAKTTYRTSYSWDGR*SLAKEYS ESSC*FSIQRRKQK**C**NRQNYRTRTVSFQY KHSHGART*LI*SL*Y**RTSHRH*NSSQSFFF *KE*CKLCDRDISSGIFITNL*SSSYEKSGKSIS RMDPTRGKTFVHARA*RNCDHFFRPPLH*KCHR P*YFNGRRRKKRRGKWDQYC*SCSKFQLGKKRL LPRCSS*RL*RSHRTKHTSWYPGSFAGVYYKLIK YISS*TCK*NKKSSG*THRYV*THS*HLSVHGC TSINGQKDLGTDAACVAQSHGICTEDAITSFST VPREKKYDLGRSTCRTTFPDPYSCLDQSKPKCVH LPRTLG*LTVSIVIADLLGRVGH*VVTDYGDIN *SFS*EFI*FGSQ*FTIG*AE*TETKKAQRERS WT*ISESFS*QVIF*RMES*SAWPSPNETEECNN HWFSRNRKGEEYSTAKNCRY**CSNTSPLN*SQ TFFTK*RNWK*SFWCFE*GAAIASK*QHF*HLG TIHC*TSQSQ*RGHEPKTASS***YWRQQC*CS* SDG*VYSRTTSKW*CLDYDKKRK*SRQPGNSQR PP*YSKQAEPDAPY**PRCALRMDFSCQCREQ* SYQLR*SFGFFQRFPI*WPKI*QFWLWNRHWGYV LC*CGFRFWPSSEC*RAGSG*SNYSSYRF*NKQ S*SASFLC*SCNYYWFRKCFPSPLTSGLQVTDS FPFYIEYRSHGTEGSAARREAPPLCSSDTR*SRN **ISIRML*CDGRRYSDWMAC*CCYCNVAKNAR HFGRCKFNHGS*NTCSSF*LPL*TLAESS*D*R *PWHFN**PDLPFSTSFNSSTENSYTLAF*GNHV D**I*TR*ITCI*TYL*YNEKKTRCFSK*RFSN TFLQYNALWITSY*PGYCQYNHQTLLTSIFFTW FAWCHNAYYGFYCSSW*SGFFSFSQCTKSRSTSS SGIFGLLSQLIL*TAFSSSQHS*CCCVSVYRC* GTYNQNCIKLGKR*ALWSCTMCSTL*FRYLDL* RTSP*VSSSSN*GSSECDLCFLKVY**NSSPRSL *HASHAGSLCT*TSDLPA*FSLENYSNPNSYHH PSFTKYRGFIL*NGQEVGSIFTSLPSGLDHGLT SKDTAPTISCYGSRKR*NRKICSQLHL*GFTWVC LWSSVF*QSKVFSHEPL*FGICRL*SFYAFGKS ERA*ASALS*LRTIF*TPASNRSENSNAAWINL YSSPHCYYTSGKSPGPLSNERWSCYANKSGV*KS RQSLQ*KY*TFS*TL*ESKYPVLCVK*YNLSVL YPDQIRREYAWRRFICWPCISQFKCQNHST*SL WKIFMGFCYTVWPTSCKWLVRTYIFHAFIVSPRE ARRASDI**MLRRYNRKRWTFSPV*KI*RNCTN LGYNKR*RRCS**ALAVFGCY*S*MLTENWNLT *YSCSTTCVHF*KTRK*CY*CYP*ATYRRKRIC* EAL**LKHESCGTR*TNTSKTSVSILLLQIAS* YIGNEFLGQTEELSSPEEK*KAT*RT*ELGFKA VPRDTQDCSILCC*RTRRQTLHSHQYRRKSSI*R FCSWSWLGGKSYKPLWFYGRTTKKQKHWIDHSI FCYLYSRGNISRVNKNAF*F**FFDQKIETFGK **SAHCLVRAY*RLQERNYSHRIW*CPYCNISNE KSHVQYSDNEKTRGSLLWSPF*WCYCEWKGSTH YG*SNSYKCKPCSEISDSIVSKLL*GESTIPAN NCPAPLRTNNI*RFCSTGFFSSSLPPFTI*CRLL PRDSTQ*NSHSNAGRWG*PGLSNVSSN*QKPHV HEAASFLWLSQ*ILRRQAAQQ*SAVATLART*G *PFQAFMSAITCMFLPVHLFEKTLDLNNFK*FVA *Y*RFKLFIVSFFFPQSKLPYFEGRGSFILHPL PS*IIMSK*FYL*FHG*L*AKIQLDN*SHYLLC PIATLWFNKYIIFYKCKILHLSICKVTAKDVPVN TQNVYRLFVMTIKHSK*MVFSISNSN*NHFSIN SSSQSNVSFLGCAGDAMLYPITRKITVLNFYV* LPSIFLMFCISSGITVKCHLFSDCGLLLLAARSW CFYVLF*APKRRWGRKEGKFSDINMLFKL*VLF KKEKGT*PRSLS*I*YC*Y*TCRSRLVYIPPSR SIFLQ*ISCSHFVLNGHLLRKCSMTLVLTACVNT SYWQTVKYKLCIIIHVVSIICNSGGER*HGI** YNKNILITSYP

Frame 1

GRELCSCRRELHLRGSGSGAPACGGERRPLETS GGGRRPARVCLAPCRAGRGIRHIGAGAEGALEP RREAGGGGGPGLDREGVGSALARKAGELMSLSG* SPPRPLPPLSAAGTRLGAGCGSGSGSGSDRMFS KKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIE NAESIDLKQFFDQHFSHIYYVFFENFVTIEASLK QKGHKSQREELDAILFIFEKILQLLPERIHQRW QFHSIGLILKKLLHTGNSLKIRREGVRLFLLWL QALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTL DNLINPPLNLQETQVTIEEITPLVPPQSGDKGQ EDLTSYFLEALLKYIVIQVKSLEWKNKENQERG FSFLFSHFKKYYLPYIFPNICKENSLYHPILDIP QMRPKPHYVVIKKDAETNEAIYCTKEPFIKARV IVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNI QRAAASLVSREESKNDNADKTDRTTEPEQSHSNT STLTEREPSSSSLCSIDEEHLTDIEIVRRVFSS KRSNVNFVTEIFRQAFLLPICEAAAMRKVVKVY QEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTD HDISMEEGEKREEENGTNTADHVRNSSWAKNGS YQGALHNASEEATEQNIRAGTQAVLQVFIINSS NIFLLEPANEIKNLLDEHTDMCKRILNIYRYMVV QVSMDKKTWEQMLLVLLRVTESVLKMPSQAFLQ FQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVY ISRELWDDLLSVLSSLTYWEELATEWSLTMETLT KVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGV GHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSAT TTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVR HFSQSEETGNEVFGALNEEQPLPRSSSTSDILE PFTVERAKVNKEDMSQKLPPLNSDIGGSSANVP DLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKD LPDILNKQNQMRPIDDPGVPSEWTSPASAGSSD LISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVT SSADVDSGSGHHQSAEEQEVASLTTLHIDSETSS LNQQAFSAEVATITGSESASPVHSPLGSRSQTP SPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLE ISEFPSECCSVMAGGTLTGWHADVATVMWRRMLG ILGDVNSIMDPEIHAQVFDYLCELWQNLAKIRD NLGISTDNLTSPSPPVLIPPLRILTPWLFKATM LTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLT HFYNIMHCGLLHIDQDIVNTIIKHCSPQFFSLG LPGATMLIMDFIVAAGRVASSAFLNAPRVEAQV LLGSLVCFPNLYCELPSLHPNIPDVAVSQFTDVK ELIIKTVLSSARDEPSGPARCVALCSLGIWICE ELVHESHHPQIKEALNVICVSLKFTNKTVAHVA CNMLHMLVHYVPRLQIYQPDSPLKIIQILIATIT HLLPSTEASSYEMDKRLVVSLLLCLLDWIMALP LKTLLQPFHATGAESDKTEKSVLNCIYKVLHGC VYGAQCFSNPRYFPMSLSDLASVDYDPFMHLESL KEPEPLHSPDSERSSKLQPVTEVKTQMQHGLIS IAARTVITHLVNHLGHYPMSGGPAMLTSQVCEN HDNHYSESTELSPELFESPNIQFFVLNNTTLVSC IQIRSEENMPGGGLSAGLASANSNVRIIVRDLS GKYSWDSAILYGPPPVSGLSEPTSFMLSLSHQE KPEEPPTSNECLEDITVKDGLSLQFKRFRETVPT WDTIRDEEDVLDELLQYLGVTSPECLQRTGISL NIPAPQPVCISEKQENDVINAILKQHTEEKEFV EKHFNDLNMKAVEQDEPIPQKPQSAFYYCRLLLS ILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQ CRETHKIAVFYVAEGQEDKHSILTNTGGSQAYE DFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPY FATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGN DEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPM KNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPI MVRATAINASRALKSLIPLYQNFYEERARYLQT IVQHHLEPTTFEDFAAQVFSPAPYHHLPSDAGS YPEILPSETPTATQVDGADLASPMSPRTSKSRMS MKLRRSSGSANKS*GDKQPSSDQQ*PP*HEHRV NPFRPSCLP*HACFFLYIYLRKHWI*IILNNL* LNIKDLSYLLFHFFSHNPSCHILRAGGVLFYTLY LPR*LCLSSFIFNFMVNCEPKYNWTISLIIYCA PLQLYGSINI*FFTNVKFYI*AFVKLQQKMYLL IHRMCTDYLL*Q*NTQNKWSLASQIPTEIILVLT LLPKAMSHFLAVQVMPCYIQ*LEKSLC*TFMFS FQVFF*CFAFQVVSLLNAICFQIVAFYYWLLDP GVSMFFFKHQKEDGEEKKENFLI*ICCSNYEYYL KKKKEHNPGV*VKSNIVNTELAGPGWYTFHPLE VFSYSR*AAHILF*MGIS*GNVA*HWY*LHV*I HHTGKP*NINYVSSFM*YL*FVTVGGKDDMVFNN TIKIFLSLPI

Frame 2

GESCAPAAESSTFVALGPGPRPVAASGGRWRRA AAAGGQPGSASLRAGPGEGSAILELGPKVPWSR GARRVEVAALAWIGKESALPWPARLGS**ASLA SLLPVHSLHFLPPGPGWEPAVAVAVAVAATGCSP RSRTGT*RSPPRRC*TPRRTH*LASSTCASSSR MQNLLILNSFSTNIFHIYTMCSLKIL*LLKLVL NRKVTSLKERNWMLYFLFLRKFYNFFQKEFISDG SFIVLD*F*RSYFTQETP*RLGGKVFVFSYYGC KLFRITVAKNSSGCFHA*SLDFQHHSLNMDLEL *IISLILHSTFKKLKSL*KKSLLLSPHNQEIKGK KISQAIFLKHF*NT*SFR*KV*NGRTKKTKKGD FHFCFHILRNITCLIFFQTSVRKTVYIILYLTS RR*DQSHIMS**RKMLKPMKQSIVQRSLSLRLVL LSFVGWFLSGWSQNHIQDLIFLGWKVKSCQRIF REQLLV*YPEKKAKMIMLIKQTELQNPNSLIPI QALSRSENLAHLVSVVLMKNISQTLK*FAEFFLL KGVM*TL*QRYFVRHFYYQFVKQQL*EKW*KYI KNGSNKRKNLCSCKSLKKL*SLLQTSLALKMSQ TMIFQWKKEKKEKRKMGPILLIMFEIPVGQKTAP TKVLFITPLKKPQNKTYELVPRQFCRCLL*THQ IYFFLNLQMK*KIFWMNTQICVNAFLTFIGTWL YKYQWTKRLGNRCCLCCSESRNLY*RCHHKLFYS SKGKKI*PWQVDLQDHFSRPL*LPGSKQT*MCT SPENFGMTYCQYCHR*PIGKSWPLSGH*LWRH* LKF*LGIYIVWISVIYHWIS*VNRNKKSTKGKEL DMNFRKFQLTSHFLEDGVVISLAKPQ*DRGVQQ PLVLQEPKRRGV*YGKKLSILMMLKYFPAQLES DIFHKVKKLEMKFLVL*MRSSHCLEVAALLTSWN HSLLNEPKSIKRT*AKNCLLLIVILAAAVLMFL I*WMSL*QNDFEVVMPRL*QEEEVVQAAWKFPK TSLIF*TSRTRCALLMTQVCPQNGLLLPVQGAVI LSAQIVIRILSALSNMMAENLTILALEPTLGLR PLLMWIQVLAIIRVLKSRKWLV*LLFI*ILKQA VLISKLSLLKLQLLLVQKVLPQSTHLWAPGHRLL PLLH*I*ITWNRRICSSTRSSTTLFFRHQMI*K LVNFHQNVVV*WQEVL*LDGMLMLLL*CGEEC* AFWEM*IQSWILKYMLKFLITSVNFGRI*LRLEI TLAFQLIT*PPLLHQF*FLH*EFLHLGFLRQPC *LININKVNYMHINLFVIQ*KEDKMFLQIEIF* HISTI*CIVDYFILTRILSIQSSNTAHLNFFHLV CLVPQCLLWILL*QLVEWLLQLFSMHQE*KHKF FWDLWFAFPTYIVNCLLFIPTFLMLLCLSLQML RNL*SKLY*ARQEMSPLVLHDV*HFVV*VFGFVK N*SMSLIILKLRKL*M*FVFP*SLLIKQ*PT*L VTCFTCWFIMYLDFRFTSLILP*KLFKS**LPS PIFYQVQRLHLMKWTRGW*YLYFSAFWTGSWPYL *RHCSNHFMLREQKAIKQKNLFSIAFIRFYMGV FMELSVLAIQGIFP*ASLIWHL*IMILLCIWKV *KSLSLCTLLTQNDLLNSSQ*QK*KLKCSMD*SL *QPALLLHIW*ITWAIIQ*AVVLLC*QVRCVKI TTIITVKVLNFLLNSLRVQISSSLC*IIQP*CP VSRSDQKRICLEEVYLLALHQPIQMSES*YVISL ENIHGILLYCMAHLL*VACQNLHLSCFHCLTKR SQKSLRHLMNA*KI*P*KMDFLSSLKDLEKLYQ LGIQ*EMKKMFLMSSCSIWVLLVLNAYRELESHL IFLLHNLCAFLKNKKMMLLMLSLSNIQKKKNLL RSTLMT*T*KLWNKMNQYLKNLSQHFIIADCFL VYWE*IPGTNGGAFIS*RKMKSYLENLGTWIQGS AERHTRLQYFMLLKDKKTNTPFSPIQEEVKHMK IL*LVLVGR*ILQTIVVLWEDYKKTKALD*PLH ILLPLQ*R*YFTCQQECLLILMIL*PKN*DIWEM MKCTLFGQSILETTGEELFPQNLVMSLL*YIQ* KITCSVFR**KNQRFPSLVPFLMVLL*MERFYP LWLEQQL*MQAVL*NL*FHCIKTSMRREHDTCKQ LSSTT*NQQHLKILQHRFFLQLPTTIYHLMPAP TQRFYPVKLPQQRR*MGLTWPLQCLLELAKAAC P*SCVVPLAQPINPKETSSPAVISSSHLSTNIGL TLSGLHVCHNMHVSSCTFI*ENTGFK*F*IICS LILKI*VIYCFIFFPTIQAAIF*GQGEFYSTPF TFLDNYV*VVLSLISWLTVSQNTIGQLVSLFIVP HCNFMVQ*IYNFLQM*NFTFKHL*SYSKRCTC* YTECVQIICYDNKTLKINGL*HLKFQLKSF*Y* LFFPKQCLISWLCR*CHVISNN*KNHCAELLCLA SKYFSNVLHFKWYHC*MPFVFRLWPFIIGC*IL VFLCSFLSTKKKMGKKRRKIF*YKYVVQIMSII *KRKRNITQESKLNLILLILNLQVQVGIHSTL*K YFLTVDKLLTFCFEWASPEEM*HDIGTNCMCKY IILANRKI*IMYHHSCSIYNL*QWGGKMTWYLI IQ*KYSYHFLS

Sequence NM_014990

AGGGAGAGAGTTGTGCTCCTGCCGCCGAGAGCTCCACCTTCGTGGCTCTGGGTCCGGGGCCCCGGCCTGTGGCGGCGAGCGGCGGCCGCTGGAGACGAGC GGCGGCGGCAGGCGGCCAGCCCGGGTCTGCCTCGCTCCGTGCAGGGCCGGGAGAGGGATCCGCCATATTGGAGCTGGGGCCGAAGGTGCCTTGGAGCCGC GGCGCGAGGCGGGTGGAGGTGGCGGCCCTGGCCTGGATCGGGAAGGAGTCGGCTCTGCCCTGGCCCGCAAGGCTGGGGAGCTAATGAGCCTCTCTGGCTA GTCTCCTCCCCGTCCACTCCCTCCACTTTCTGCCGCCGGGACCCGGCTGGGAGCCGGCTGTGGCAGTGGCAGTGGCAGTGGCAGCGACAGGATGTTCTCC AAGAAGCCGCACGGGGACGTGAAGAAGTCCACCCAGAAGGTGCTAGACACCAAGAAGGACGCACTGACTCGCCTCAAGCACCTGCGCATCGTCATCGAGA ATGCAGAATCTATTGATCTTAAACAGTTTTTCGACCAACATTTTTCACATATATACTATGTGTTCTTTGAAAATTTTGTGACTATTGAAGCTAGTCTTAA ACAGAAAGGTCACAAGTCTCAAAGAGAGGAATTGGATGCTATACTTTTTATTTTTGAGAAAATTTTACAACTTCTTCCAGAAAGAATTCATCAGCGATGG CAGTTTCATAGTATTGGATTGATTTTAAAGAAGCTACTTCACACAGGAAACTCCTTAAAGATTAGGCGGGAAGGTGTTCGTCTTTTCTTACTATGGTTGC AAGCTCTTCAGAATAACTGTAGCAAAGAACAGCTCTGGATGTTTTCATGCTTAATCCCTGGATTTTCAGCACCACAGTCTGAACATGGACCTCGAACTTT AGATAATCTCATTAATCCTCCACTCAACCTTCAAGAAACTCAAGTCACTATAGAAGAAATCACTCCTCTTGTCCCCCCACAATCAGGAGATAAAGGGCAA GAAGATCTCACAAGCTATTTTCTTGAAGCACTTCTAAAATACATAGTCATTCAGGTAAAAAGTTTAGAATGGAAGAACAAAGAAAACCAAGAAAGGGGAT TTTCATTTTTGTTTTCACATTTTAAGAAATATTACTTGCCTTATATTTTTCCAAACATCTGTAAGGAAAACAGTTTATATCATCCTATACTTGACATCCC GCAGATGAGACCAAAGCCACATTATGTCGTGATAAAGAAAGATGCTGAAACCAATGAAGCAATCTATTGTACAAAGGAGCCTTTCATTAAGGCTCGTGTT ATTGTCATTCGTTGGCTGGTTTCTTTCTGGCTGGAGCCAAAACCACATACAGGACCTCATATTCCTGGGATGGAAGGTGAAGTCTTGCCAAAGAATATTC AGAGAGCAGCTGCTAGTTTAGTATCCAGAGAAGAAAGCAAAAATGATAATGCTGATAAAACAGACAGAACTACAGAACCCGAACAGTCTCATTCCAATAC AAGCACTCTCACGGAGCGAGAACCTAGCTCATCTAGTCTCTGTAGTATTGATGAAGAACATCTCACAGACATTGAAATAGTTCGCAGAGTTTTTTCTTCT AAAAGGAGTAATGTAAACTTTGTGACAGAGATATTTCGTCAGGCATTTTTATTACCAATTTGTGAAGCAGCAGCTATGAGAAAAGTGGTAAAAGTATATC AAGAATGGATCCAACAAGAGGAAAAACCTTTGTTCATGCAAGAGCCTGAAGAAATTGTGATCACTTCTTCAGACCTCCCTTGCATTGAAAATGTCACAGA CCATGATATTTCAATGGAAGAAGGAGAAAAAAGAGAAGAGGAAAATGGGACCAATACTGCTGATCATGTTCGAAATTCCAGTTGGGCAAAAAACGGCTCC TACCAAGGTGCTCTTCATAACGCCTCTGAAGAAGCCACAGAACAAAACATACGAGCTGGTACCCAGGCAGTTTTGCAGGTGTTTATTATAAACTCATCAA ATATATTTCTTCTTGAACCTGCAAATGAAATAAAAAATCTTCTGGATGAACACACAGATATGTGTAAACGCATTCTTAACATTTATCGGTACATGGTTGT ACAAGTATCAATGGACAAAAAGACTTGGGAACAGATGCTGCTTGTGTTGCTCAGAGTCACGGAATCTGTACTGAAGATGCCATCACAAGCTTTTCTACAG TTCCAAGGGAAAAAAAATATGACCTTGGCAGGTCGACTTGCAGGACCACTTTTCCAGACCCTTATAGTTGCCTGGATCAAAGCAAACCTAAATGTGTACA TCTCCCGAGAACTTTGGGATGACTTACTGTCAGTATTGTCATCGCTGACCTATTGGGAAGAGTTGGCCACTGAGTGGTCACTGACTATGGAGACATTAAC TAAAGTTTTAGCTAGGAATTTATATAGTTTGGATCTCAGTGATTTACCATTGGATAAGCTGAGTGAACAGAAACAAAAAAAGCACAAAGGGAAAGGAGTT GGACATGAATTTCAGAAAGTTTCAGTTGACAAGTCATTTTCTAGAGGATGGAGTCGTGATCAGCCTGGCCAAGCCCCAATGAGACAGAGGAGTGCAACAA CCACTGGTTCTCCAGGAACCGAAAAGGCGAGGAGTATAGTACGGCAAAAAACTGTCGATATTGATGATGCTCAAATACTTCCCCGCTCAACTAGAGTCAG ACATTTTTCACAAAGTGAAGAAACTGGAAATGAAGTTTTTGGTGCTTTGAATGAGGAGCAGCCATTGCCTCGAAGTAGCAGCACTTCTGACATCTTGGAA CCATTCACTGTTGAACGAGCCAAAGTCAATAAAGAGGACATGAGCCAAAAACTGCCTCCTCTTAATAGTGATATTGGCGGCAGCAGTGCTAATGTTCCTG ATCTGATGGATGAGTTTATAGCAGAACGACTTCGAAGTGGTAATGCCTCGACTATGACAAGAAGAGGAAGTAGTCCAGGCAGCCTGGAAATTCCCAAAGA CCTCCCTGATATTCTAAACAAGCAGAACCAGATGCGCCCTATTGATGACCCAGGTGTGCCCTCAGAATGGACTTCTCCTGCCAGTGCAGGGAGCAGTGAT CTTATCAGCTCAGATAGTCATTCGGATTCTTTCAGCGCTTTCCAATATGATGGCCGAAAATTTGACAATTTTGGCTTTGGAACCGACACTGGGGTTACGT CCTCTGCTGATGTGGATTCAGGTTCTGGCCATCATCAGAGTGCTGAAGAGCAGGAAGTGGCTAGTCTAACTACTCTTCATATAGATTCTGAAACAAGCAG TCTTAATCAGCAAGCTTTCTCTGCTGAAGTTGCAACTATTACTGGTTCAGAAAGTGCTTCCCCAGTCCACTCACCTCTGGGCTCCAGGTCACAGACTCCT TCCCCTTCTACATTGAATATAGATCACATGGAACAGAAGGATCTGCAGCTCGACGAGAAGCTCCACCACTCTGTTCTTCAGACACCAGATGATCTAGAAA TTAGTGAATTTCCATCAGAATGTTGTAGTGTGATGGCAGGAGGTACTCTGACTGGATGGCATGCTGATGTTGCTACTGTAATGTGGCGAAGAATGCTAGG CATTTTGGGAGATGTAAATTCAATCATGGATCCTGAAATACATGCTCAAGTTTTTGATTACCTCTGTGAACTTTGGCAGAATCTAGCTAAGATTAGAGAT AACCTTGGCATTTCAACTGATAACCTGACCTCCCCTTCTCCACCAGTTTTAATTCCTCCACTGAGAATTCTTACACCTTGGCTTTTTAAGGCAACCATGT TGACTGATAAATATAAACAAGGTAAATTACATGCATATAAACTTATTTGTAATACAATGAAAAGAAGACAAGATGTTTCTCCAAATAGAGATTTTCTAAC ACATTTCTACAATATAATGCATTGTGGATTACTTCATATTGACCAGGATATTGTCAATACAATCATCAAACACTGCTCACCTCAATTTTTTTCACTTGGT TTGCCTGGTGCCACAATGCTTATTATGGATTTTATTGTAGCAGCTGGTAGAGTGGCTTCTTCAGCTTTTCTCAATGCACCAAGAGTAGAAGCACAAGTTC TTCTGGGATCTTTGGTTTGCTTTCCCAACTTATATTGTGAACTGCCTTCTCTTCATCCCAACATTCCTGATGTTGCTGTGTCTCAGTTTACAGATGTTAA GGAACTTATAATCAAAACTGTATTAAGCTCGGCAAGAGATGAGCCCTCTGGTCCTGCACGATGTGTAGCACTTTGTAGTTTAGGTATTTGGATTTGTGAA GAACTAGTCCATGAGTCTCATCATCCTCAAATTAAGGAAGCTCTGAATGTGATTTGTGTTTCCTTAAAGTTTACTAATAAAACAGTAGCCCACGTAGCTT GTAACATGCTTCACATGCTGGTTCATTATGTACCTAGACTTCAGATTTACCAGCCTGATTCTCCCTTGAAAATTATTCAAATCCTAATAGCTACCATCAC CCATCTTTTACCAAGTACAGAGGCTTCATCTTATGAAATGGACAAGAGGTTGGTAGTATCTTTACTTCTCTGCCTTCTGGACTGGATCATGGCCTTACCT CTAAAGACACTGCTCCAACCATTTCATGCTACGGGAGCAGAAAGCGATAAAACAGAAAAATCTGTTCTCAATTGCATTTATAAGGTTTTACATGGGTGTG TTTATGGAGCTCAGTGTTTTAGCAATCCAAGGTATTTTCCCATGAGCCTCTCTGATTTGGCATCTGTAGATTATGATCCTTTTATGCATTTGGAAAGTCT GAAAGAGCCTGAGCCTCTGCACTCTCCTGACTCAGAACGATCTTCTAAACTCCAGCCAGTAACAGAAGTGAAAACTCAAATGCAGCATGGATTAATCTCT ATAGCAGCCCGCACTGTTATTACACATCTGGTAAATCACCTGGGCCATTATCCAATGAGCGGTGGTCCTGCTATGCTAACAAGTCAGGTGTGTGAAAATC ACGACAATCATTACAGTGAAAGTACTGAACTTTCTCCTGAACTCTTTGAGAGTCCAAATATCCAGTTCTTTGTGTTAAATAATACAACCTTAGTGTCCTG TATCCAGATCAGATCAGAAGAGAATATGCCTGGAGGAGGTTTATCTGCTGGCCTTGCATCAGCCAATTCAAATGTCAGAATCATAGTACGTGATCTCTCT GGAAAATATTCATGGGATTCTGCTATACTGTATGGCCCACCTCCTGTAAGTGGCTTGTCAGAACCTACATCTTTCATGCTTTCATTGTCTCACCAAGAGA AGCCAGAAGAGCCTCCGACATCTAATGAATGCTTAGAAGATATAACCGTAAAAGATGGACTTTCTCTCCAGTTTAAAAGATTTAGAGAAACTGTACCAAC TTGGGATACAATAAGAGATGAAGAAGATGTTCTTGATGAGCTCTTGCAGTATTTGGGTGTTACTAGTCCTGAATGCTTACAGAGAACTGGAATCTCACTT AATATTCCTGCTCCACAACCTGTGTGCATTTCTGAAAAACAAGAAAATGATGTTATTAATGCTATCCTTAAGCAACATACAGAAGAAAAAGAATTTGTTG AGAAGCACTTTAATGACTTAAACATGAAAGCTGTGGAACAAGATGAACCAATACCTCAAAAACCTCAGTCAGCATTTTATTATTGCAGATTGCTTCTTAG TATATTGGGAATGAATTCCTGGGACAAACGGAGGAGCTTTCATCTCCTGAAGAAAAATGAAAAGCTACTTAGAGAACTTAGGAACTTGGATTCAAGGCAG TGCCGAGAGACACACAAGATTGCAGTATTTTATGTTGCTGAAGGACAAGAAGACAAACACTCCATTCTCACCAATACAGGAGGAAGTCAAGCATATGAAG ATTTTGTAGCTGGTCTTGGTTGGGAGGTAAATCTTACAAACCATTGTGGTTTTATGGGAGGACTACAAAAAAACAAAAGCACTGGATTGACCACTCCATA TTTTGCTACCTCTACAGTAGAGGTAATATTTCACGTGTCAACAAGAATGCCTTCTGATTCTGATGATTCTTTGACCAAAAAATTGAGACATTTGGGAAAT GATGAAGTGCACATTGTTTGGTCAGAGCATACTAGAGACTACAGGAGAGGAATTATTCCCACAGAATTTGGTGATGTCCTTATTGTAATATATCCAATGA AAAATCACATGTTCAGTATTCAGATAATGAAAAAACCAGAGGTTCCCTTCTTTGGTCCCCTTTTTGATGGTGCTATTGTGAATGGAAAGGTTCTACCCAT TATGGTTAGAGCAACAGCTATAAATGCAAGCCGTGCTCTGAAATCTCTGATTCCATTGTATCAAAACTTCTATGAGGAGAGAGCACGATACCTGCAAACA ATTGTCCAGCACCACTTAGAACCAACAACATTTGAAGATTTTGCAGCACAGGTTTTTTCTCCAGCTCCCTACCACCATTTACCATCTGATGCCGATCATT AAATATCAGTTCTGTTTATCTGAAGGCTCCTACCCAGAGATTCTACCCAGTGAAACTCCCACAGCAACGCAGGTAGATGGGGCTGACCTGGCCTCTCCAA TGTCTCCTCGAACTAGCAAAAGCCGCATGTCCATGAAGCTGCGTCGTTCCTCTGGCTCAGCCAATAAATCCTAAGGAGACAAGCAGCCCAGCAGTGATCA GCAGTAGCCACCTTAGCACGAACATAGGGTTAACCCTTTCAGGCCTTCATGTCTGCCATAACATGCATGTTTCTTCCTGTACATTTATTTGAGAAAACAC TGGATTTAAATAATTTTAAATAATTTGTAGCTTAATATTAAAGATTTAAGTTATTTATTGTTTCATTTTTTTTCCCACAATCCAAGCTGCCATATTTTGA GGGCAGGGGGAGTTTTATTCTACACCCTTTACCTTCCTAGATAATTATGTCTAAGTAGTTTTATCTTTAATTTCATGGTTAACTGTGAGCCAAAATACAA TTGGACAATTAGTCTCATTATTTATTGTGCCCCATTGCAACTTTATGGTTCAATAAATATATAATTTTTTACAAATGTAAAATTTTACATTTAAGCATTT GTAAAGTTACAGCAAAAGATGTACCTGTTAATACACAGAATGTGTACAGATTATTTGTTATGACAATAAAACACTCAAAATAAATGGTCTTTAGCATCTC AAATTCCAACTGAAATCATTTTAGTATTAACTCTTCTTCCCAAAGCAATGTCTCATTTCTTGGCTGTGCAGGTGATGCCATGTTATATCCAATAACTAGA AAAATCACTGTGCTGAACTTTTATGTTTAGCTTCCAAGTATTTTTCTAATGTTTTGCATTTCAAGTGGTATCACTGTTAAATGCCATTTGTTTTCAGATT GTGGCCTTTTATTATTGGCTGCTAGATCCTGGTGTTTCTATGTTCTTTTTTAAGCACCAAAAAGAAGATGGGGAAGAAAAGAAGGAAAATTTTCTGATAT AAATATGTTGTTCAAATTATGAGTATTATTTAAAAAAGAAAAAGGAACATAACCCAGGAGTCTAAGTTAAATCTAATATTGTTAATACTGAACTTGCAGG TCCAGGTTGGTATACATTCCACCCTCTAGAAGTATTTTCTTACAGTAGATAAGCTGCTCACATTTTGTTTTGAATGGGCATCTCCTGAGGAAATGTAGCA TGACATTGGTACTAACTGCATGTGTAAATACATCATACTGGCAAACCGTAAAATATAAATTATGTATCATCATTCATGTAGTATCTATAATTTGTAACAG TGGGGGGGAAAGATGACATGGTATTTAATAATACAATAAAAATATTCTTATCACTTCCTATCCA

refseq_GARNL1.F1 (forward primer)
refseq_GARNL1.R1 (reverse primer)
Single exon skipping

Frame 0

RERVVLLPPRAPPSWLWVRGPGLWRRAAAAGDE RRRQAASPGLPRSVQGRERDPPYWSWGRRCLGAA ARGGWRWRPWPGSGRSRLCPGPQGWGANEPLWL VSSPSTPSTFCRRDPAGSRLWQWQWQWQRQDVL QEAARGREEVHPEGARHQEGRTDSPQAPAHRHRE CRIY*S*TVFRPTFFTYILCVL*KFCDY*S*S* TERSQVSKRGIGCYTFYF*ENFTTSSRKNSSAM AVS*YWIDFKEATSHRKLLKD*AGRCSSFLTMVA SSSE*L*QRTALDVFMLNPWIFSTTV*TWTSNF R*SH*SSTQPSRNSSHYRRNHSSCPPTIRR*RA RRSHKLFS*STSKIHSHSGKKFRMEEQRKPRKGI FIFVFTF*EILLALYFSKHL*GKQFISSYT*HP ADETKATLCRDKERC*NQ*SNLLYKGAFH*GSC YCHSLAGFFLAGAKTTYRTSYSWDGR*SLAKEYS ESSC*FSIQRRKQK**C**NRQNYRTRTVSFQY KHSHGART*LI*SL*Y**RTSHRH*NSSQSFFF *KE*CKLCDRDISSGIFITNL*SSSYEKSGKSIS RMDPTRGKTFVHARA*RNCDHFFRPPLH*KCHR P*YFNGRRRKKRRGKWDQYC*SCSKFQLGKKRL LPRCSS*RL*RSHRTKHTSWYPGSFAGVYYKLIK YISS*TCK*NKKSSG*THRYV*THS*HLSVHGC TSINGQKDLGTDAACVAQSHGICTEDAITSFST VPREKKYDLGRSTCRTTFPDPYSCLDQSKPKCVH LPRTLG*LTVSIVIADLLGRVGH*VVTDYGDIN *SFS*EFI*FGSQ*FTIG*AE*TETKKAQRERS WT*ISESFS*QVIF*RMES*SAWPSPNETEECNN HWFSRNRKGEEYSTAKNCRY**CSNTSPLN*SQ TFFTK*RNWK*SFWCFE*GAAIASK*QHF*HLG TIHC*TSQSQ*RGHEPKTASS***YWRQQC*CS* SDG*VYSRTTSKW*CLDYDKKRK*SRQPGNSQR PP*YSKQAEPDAPY**PRCALRMDFSCQCREQ* SYQLR*SFGFFQRFPI*WPKI*QFWLWNRHWGYV LC*CGFRFWPSSEC*RAGSG*SNYSSYRF*NKQ S*SASFLC*SCNYYWFRKCFPSPLTSGLQVTDS FPFYIEYRSHGTEGSAARREAPPLCSSDTR*SRN **ISIRML*CDGRRYSDWMAC*CCYCNVAKNAR HFGRCKFNHGS*NTCSSF*LPL*TLAESS*D*R *PWHFN**PDLPFSTSFNSSTENSYTLAF*GNHV D**I*TR*ITCI*TYL*YNEKKTRCFSK*RFSN TFLQYNALWITSY*PGYCQYNHQTLLTSIFFTW FAWCHNAYYGFYCSSW*SGFFSFSQCTKSRSTSS SGIFGLLSQLIL*TAFSSSQHS*CCCVSVYRC* GTYNQNCIKLGKR*ALWSCTMCSTL*FRYLDL* RTSP*VSSSSN*GSSECDLCFLKVY**NSSPRSL *HASHAGSLCT*TSDLPA*FSLENYSNPNSYHH PSFTKYRGFIL*NGQEVGSIFTSLPSGLDHGLT SKDTAPTISCYGSRKR*NRKICSQLHL*GFTWVC LWSSVF*QSKVFSHEPL*FGICRL*SFYAFGKS ERA*ASALS*LRTIF*TPASNRSENSNAAWINL YSSPHCYYTSGKSPGPLSNERWSCYANKSGV*KS RQSLQ*KY*TFS*TL*ESKYPVLCVK*YNLSVL YPDQIRREYAWRRFICWPCISQFKCQNHST*SL WKIFMGFCYTVWPTSCKWLVRTYIFHAFIVSPRE ARRASDI**MLRRYNRKRWTFSPV*KI*RNCTN LGYNKR*RRCS**ALAVFGCY*S*MLTENWNLT *YSCSTTCVHF*KTRK*CY*CYP*ATYRRKRIC* EAL**LKHESCGTR*TNTSKTSVSILLLQIAS* YIGNEFLGQTEELSSPEEK*KAT*RT*ELGFKA VPRDTQDCSILCC*RTRRQTLHSHQYRRKSSI*R FCSWSWLGGKSYKPLWFYGRTTKKQKHWIDHSI FCYLYSRGNISRVNKNAF*F**FFDQKIETFGK **SAHCLVRAY*RLQERNYSHRIW*CPYCNISNE KSHVQYSDNEKTRGSLLWSPF*WCYCEWKGSTH YG*SNSYKCKPCSEISDSIVSKLL*GESTIPAN NCPAPLRTNNI*RFCSTGFFSSSLPPFTI*CRSL NISSVYLKAPTQRFYPVKLPQQRR*MGLTWPLQ CLLELAKAACP*SCVVPLAQPINPKETSSPAVI SSSHLSTNIGLTLSGLHVCHNMHVSSCTFI*ENT GFK*F*IICSLILKI*VIYCFIFFPTIQAAIF* GQGEFYSTPFTFLDNYV*VVLSLISWLTVSQNT IGQLVSLFIVPHCNFMVQ*IYNFLQM*NFTFKHL *SYSKRCTC*YTECVQIICYDNKTLKINGL*HL KFQLKSF*Y*LFFPKQCLISWLCR*CHVISNN* KNHCAELLCLASKYFSNVLHFKWYHC*MPFVFRL WPFIIGC*ILVFLCSFLSTKKKMGKKRRKIF*Y KYVVQIMSII*KRKRNITQESKLNLILLILNLQ VQVGIHSTL*KYFLTVDKLLTFCFEWASPEEM*H DIGTNCMCKYIILANRKI*IMYHHSCSIYNL*Q WGGKMTWYLIIQ*KYSYHFLS

Frame 1

GRELCSCRRELHLRGSGSGAPACGGERRPLETS GGGRRPARVCLAPCRAGRGIRHIGAGAEGALEP RREAGGGGGPGLDREGVGSALARKAGELMSLSG* SPPRPLPPLSAAGTRLGAGCGSGSGSGSDRMFS KKPHGDVKKSTQKVLDTKKDALTRLKHLRIVIE NAESIDLKQFFDQHFSHIYYVFFENFVTIEASLK QKGHKSQREELDAILFIFEKILQLLPERIHQRW QFHSIGLILKKLLHTGNSLKIRREGVRLFLLWL QALQNNCSKEQLWMFSCLIPGFSAPQSEHGPRTL DNLINPPLNLQETQVTIEEITPLVPPQSGDKGQ EDLTSYFLEALLKYIVIQVKSLEWKNKENQERG FSFLFSHFKKYYLPYIFPNICKENSLYHPILDIP QMRPKPHYVVIKKDAETNEAIYCTKEPFIKARV IVIRWLVSFWLEPKPHTGPHIPGMEGEVLPKNI QRAAASLVSREESKNDNADKTDRTTEPEQSHSNT STLTEREPSSSSLCSIDEEHLTDIEIVRRVFSS KRSNVNFVTEIFRQAFLLPICEAAAMRKVVKVY QEWIQQEEKPLFMQEPEEIVITSSDLPCIENVTD HDISMEEGEKREEENGTNTADHVRNSSWAKNGS YQGALHNASEEATEQNIRAGTQAVLQVFIINSS NIFLLEPANEIKNLLDEHTDMCKRILNIYRYMVV QVSMDKKTWEQMLLVLLRVTESVLKMPSQAFLQ FQGKKNMTLAGRLAGPLFQTLIVAWIKANLNVY ISRELWDDLLSVLSSLTYWEELATEWSLTMETLT KVLARNLYSLDLSDLPLDKLSEQKQKKHKGKGV GHEFQKVSVDKSFSRGWSRDQPGQAPMRQRSAT TTGSPGTEKARSIVRQKTVDIDDAQILPRSTRVR HFSQSEETGNEVFGALNEEQPLPRSSSTSDILE PFTVERAKVNKEDMSQKLPPLNSDIGGSSANVP DLMDEFIAERLRSGNASTMTRRGSSPGSLEIPKD LPDILNKQNQMRPIDDPGVPSEWTSPASAGSSD LISSDSHSDSFSAFQYDGRKFDNFGFGTDTGVT SSADVDSGSGHHQSAEEQEVASLTTLHIDSETSS LNQQAFSAEVATITGSESASPVHSPLGSRSQTP SPSTLNIDHMEQKDLQLDEKLHHSVLQTPDDLE ISEFPSECCSVMAGGTLTGWHADVATVMWRRMLG ILGDVNSIMDPEIHAQVFDYLCELWQNLAKIRD NLGISTDNLTSPSPPVLIPPLRILTPWLFKATM LTDKYKQGKLHAYKLICNTMKRRQDVSPNRDFLT HFYNIMHCGLLHIDQDIVNTIIKHCSPQFFSLG LPGATMLIMDFIVAAGRVASSAFLNAPRVEAQV LLGSLVCFPNLYCELPSLHPNIPDVAVSQFTDVK ELIIKTVLSSARDEPSGPARCVALCSLGIWICE ELVHESHHPQIKEALNVICVSLKFTNKTVAHVA CNMLHMLVHYVPRLQIYQPDSPLKIIQILIATIT HLLPSTEASSYEMDKRLVVSLLLCLLDWIMALP LKTLLQPFHATGAESDKTEKSVLNCIYKVLHGC VYGAQCFSNPRYFPMSLSDLASVDYDPFMHLESL KEPEPLHSPDSERSSKLQPVTEVKTQMQHGLIS IAARTVITHLVNHLGHYPMSGGPAMLTSQVCEN HDNHYSESTELSPELFESPNIQFFVLNNTTLVSC IQIRSEENMPGGGLSAGLASANSNVRIIVRDLS GKYSWDSAILYGPPPVSGLSEPTSFMLSLSHQE KPEEPPTSNECLEDITVKDGLSLQFKRFRETVPT WDTIRDEEDVLDELLQYLGVTSPECLQRTGISL NIPAPQPVCISEKQENDVINAILKQHTEEKEFV EKHFNDLNMKAVEQDEPIPQKPQSAFYYCRLLLS ILGMNSWDKRRSFHLLKKNEKLLRELRNLDSRQ CRETHKIAVFYVAEGQEDKHSILTNTGGSQAYE DFVAGLGWEVNLTNHCGFMGGLQKNKSTGLTTPY FATSTVEVIFHVSTRMPSDSDDSLTKKLRHLGN DEVHIVWSEHTRDYRRGIIPTEFGDVLIVIYPM KNHMFSIQIMKKPEVPFFGPLFDGAIVNGKVLPI MVRATAINASRALKSLIPLYQNFYEERARYLQT IVQHHLEPTTFEDFAAQVFSPAPYHHLPSDADH *ISVLFI*RLLPRDSTQ*NSHSNAGRWG*PGLSN VSSN*QKPHVHEAASFLWLSQ*ILRRQAAQQ*S AVATLART*G*PFQAFMSAITCMFLPVHLFEKT LDLNNFK*FVA*Y*RFKLFIVSFFFPQSKLPYFE GRGSFILHPLPS*IIMSK*FYL*FHG*L*AKIQ LDN*SHYLLCPIATLWFNKYIIFYKCKILHLSI CKVTAKDVPVNTQNVYRLFVMTIKHSK*MVFSIS NSN*NHFSINSSSQSNVSFLGCAGDAMLYPITR KITVLNFYV*LPSIFLMFCISSGITVKCHLFSD CGLLLLAARSWCFYVLF*APKRRWGRKEGKFSDI NMLFKL*VLFKKEKGT*PRSLS*I*YC*Y*TCR SRLVYIPPSRSIFLQ*ISCSHFVLNGHLLRKCS MTLVLTACVNTSYWQTVKYKLCIIIHVVSIICNS GGER*HGI**YNKNILITSYP

Frame 2

GESCAPAAESSTFVALGPGPRPVAASGGRWRRA AAAGGQPGSASLRAGPGEGSAILELGPKVPWSR GARRVEVAALAWIGKESALPWPARLGS**ASLA SLLPVHSLHFLPPGPGWEPAVAVAVAVAATGCSP RSRTGT*RSPPRRC*TPRRTH*LASSTCASSSR MQNLLILNSFSTNIFHIYTMCSLKIL*LLKLVL NRKVTSLKERNWMLYFLFLRKFYNFFQKEFISDG SFIVLD*F*RSYFTQETP*RLGGKVFVFSYYGC KLFRITVAKNSSGCFHA*SLDFQHHSLNMDLEL *IISLILHSTFKKLKSL*KKSLLLSPHNQEIKGK KISQAIFLKHF*NT*SFR*KV*NGRTKKTKKGD FHFCFHILRNITCLIFFQTSVRKTVYIILYLTS RR*DQSHIMS**RKMLKPMKQSIVQRSLSLRLVL LSFVGWFLSGWSQNHIQDLIFLGWKVKSCQRIF REQLLV*YPEKKAKMIMLIKQTELQNPNSLIPI QALSRSENLAHLVSVVLMKNISQTLK*FAEFFLL KGVM*TL*QRYFVRHFYYQFVKQQL*EKW*KYI KNGSNKRKNLCSCKSLKKL*SLLQTSLALKMSQ TMIFQWKKEKKEKRKMGPILLIMFEIPVGQKTAP TKVLFITPLKKPQNKTYELVPRQFCRCLL*THQ IYFFLNLQMK*KIFWMNTQICVNAFLTFIGTWL YKYQWTKRLGNRCCLCCSESRNLY*RCHHKLFYS SKGKKI*PWQVDLQDHFSRPL*LPGSKQT*MCT SPENFGMTYCQYCHR*PIGKSWPLSGH*LWRH* LKF*LGIYIVWISVIYHWIS*VNRNKKSTKGKEL DMNFRKFQLTSHFLEDGVVISLAKPQ*DRGVQQ PLVLQEPKRRGV*YGKKLSILMMLKYFPAQLES DIFHKVKKLEMKFLVL*MRSSHCLEVAALLTSWN HSLLNEPKSIKRT*AKNCLLLIVILAAAVLMFL I*WMSL*QNDFEVVMPRL*QEEEVVQAAWKFPK TSLIF*TSRTRCALLMTQVCPQNGLLLPVQGAVI LSAQIVIRILSALSNMMAENLTILALEPTLGLR PLLMWIQVLAIIRVLKSRKWLV*LLFI*ILKQA VLISKLSLLKLQLLLVQKVLPQSTHLWAPGHRLL PLLH*I*ITWNRRICSSTRSSTTLFFRHQMI*K LVNFHQNVVV*WQEVL*LDGMLMLLL*CGEEC* AFWEM*IQSWILKYMLKFLITSVNFGRI*LRLEI TLAFQLIT*PPLLHQF*FLH*EFLHLGFLRQPC *LININKVNYMHINLFVIQ*KEDKMFLQIEIF* HISTI*CIVDYFILTRILSIQSSNTAHLNFFHLV CLVPQCLLWILL*QLVEWLLQLFSMHQE*KHKF FWDLWFAFPTYIVNCLLFIPTFLMLLCLSLQML RNL*SKLY*ARQEMSPLVLHDV*HFVV*VFGFVK N*SMSLIILKLRKL*M*FVFP*SLLIKQ*PT*L VTCFTCWFIMYLDFRFTSLILP*KLFKS**LPS PIFYQVQRLHLMKWTRGW*YLYFSAFWTGSWPYL *RHCSNHFMLREQKAIKQKNLFSIAFIRFYMGV FMELSVLAIQGIFP*ASLIWHL*IMILLCIWKV *KSLSLCTLLTQNDLLNSSQ*QK*KLKCSMD*SL *QPALLLHIW*ITWAIIQ*AVVLLC*QVRCVKI TTIITVKVLNFLLNSLRVQISSSLC*IIQP*CP VSRSDQKRICLEEVYLLALHQPIQMSES*YVISL ENIHGILLYCMAHLL*VACQNLHLSCFHCLTKR SQKSLRHLMNA*KI*P*KMDFLSSLKDLEKLYQ LGIQ*EMKKMFLMSSCSIWVLLVLNAYRELESHL IFLLHNLCAFLKNKKMMLLMLSLSNIQKKKNLL RSTLMT*T*KLWNKMNQYLKNLSQHFIIADCFL VYWE*IPGTNGGAFIS*RKMKSYLENLGTWIQGS AERHTRLQYFMLLKDKKTNTPFSPIQEEVKHMK IL*LVLVGR*ILQTIVVLWEDYKKTKALD*PLH ILLPLQ*R*YFTCQQECLLILMIL*PKN*DIWEM MKCTLFGQSILETTGEELFPQNLVMSLL*YIQ* KITCSVFR**KNQRFPSLVPFLMVLL*MERFYP LWLEQQL*MQAVL*NL*FHCIKTSMRREHDTCKQ LSSTT*NQQHLKILQHRFFLQLPTTIYHLMPII KYQFCLSEGSYPEILPSETPTATQVDGADLASP MSPRTSKSRMSMKLRRSSGSANKS*GDKQPSSDQ Q*PP*HEHRVNPFRPSCLP*HACFFLYIYLRKH WI*IILNNL*LNIKDLSYLLFHFFSHNPSCHIL RAGGVLFYTLYLPR*LCLSSFIFNFMVNCEPKYN WTISLIIYCAPLQLYGSINI*FFTNVKFYI*AF VKLQQKMYLLIHRMCTDYLL*Q*NTQNKWSLAS QIPTEIILVLTLLPKAMSHFLAVQVMPCYIQ*LE KSLC*TFMFSFQVFF*CFAFQVVSLLNAICFQI VAFYYWLLDPGVSMFFFKHQKEDGEEKKENFLI *ICCSNYEYYLKKKKEHNPGV*VKSNIVNTELAG PGWYTFHPLEVFSYSR*AAHILF*MGIS*GNVA *HWY*LHV*IHHTGKP*NINYVSSFM*YL*FVT VGGKDDMVFNNTIKIFLSLPI