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Sequences

Sequence NM_001013005

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTGGCATATGTGCACACCACT
GGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGCAAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTG
CTGAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTGACAACTCATCAGTGAAATTAGAATGATATTTTCATCTC
CTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGGCAAGAGATACCTTCAAGAAGTT
AACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTCTCCACACCAAGAAGCTTTATCA
GTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAGGCTGTGTGTGAAATGAGTAAAC
AATCTTTGCAAGTCCTAAGTAAACAAAGCTAACTGTCGACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATA
GAGGAAGACAGCTCTTTCGGGATAACCACCTGATACCTGCAGAAACCCCCAGTCCTGTTATTTTCAGTGATTTTCCATTTATCTTTAATTCGCTATCCAA
AATTAAATTATTGCAAGCTGATTCACATATAAAGATGCAGGCTGGAGTACAATGGTGCAATCTCAGCTCACCACAACCTCTGCCTCCCGGGTTCAAGCGA
TTCTTCTGCCTCAGCCTCCCAAATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGA
TTTATACTTAGAGTCAGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAAT
TTATTAATGAAATTTGTCCTGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTA
TCCTGAAATGGGTTCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAAT
TTAAATGTTGCTAACCTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGG
GGAAGAGTTTGCAAGAAGTTCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTT
AATTCCAAATGGGATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTT
TATGAGGAATTTCAGAGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTG
ATTATGACTGGAAACAGTTTGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACT
AACCTTGGATGAAAAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCT
GAAACTTTCAGTGAAAGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTC
AAGTAGCCATCAACAACAACAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCC
TTCTGTTCTTCCTTACACCTAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGG
TCAAAGGGTGCAAAATCTCACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGT
CTGAACACTGGCCTGTGATTGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCT
GGCCAATGATTGGTTCATTCCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTG
GCTGTGAGTCAGTCTTTCATTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCA
CTTGCTCTAGCCCACTCCCACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F5 (forward primer)
  • refseq_HERC6.R4 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEVITPWHMCTPL
VRWYLLVMDQVTQASQLIRRP*QRTLTLAA*FL
LKTSWMFKSNTFLLEHMPTL*QLISEIRMIFSS
PACLTASFLKKRGTGETTSIDVDLEMARDTFKKL
TKKEWISSMITTCLEDDLLRALPCHSPHQEALS
VFLLLPECPVMHDSKNWKNLVVPFAKAVCEMSK
QSLQVLSKQS*LSTTRKYFQHK*TLQLIKLLYR*
RKTALSG*PPDTCRNPQSCYFQ*FSIYL*FAIQ
N*IIAS*FTYKDAGWSTMVQSQLTTTSASRVQA
ILLPQPPKCQKRKHTCLCMKQFCKKRMNFLHHPD
LYLESDEVAWLKMLCVN*VKLKLLTSAKY*WLN
LLMKFVLSLEGLVQSSSTVCLKR*PSQNMECSC
ILKWVPACGFLPSLNLRRKDISSLECCVDSPYSI
*MLLTFLSHWLCIKNFWTKSHHWKI*KNSVLGW
GRVCKKF*MMLLMTLEMRSAYAFLYTGTKMMLT
*FQMGSPYLWTKPTRETMFLSILITFSTSL*KQF
MRNFREDFIESVRRRYLDISTLKN**QQSLEIL
IMTGNSLNRIQSMSKDTKNHILLYSCFGRLSTN
*PWMKRKNSSFSLQDVIGCMQEAYRKWK*YFAVL
KLSVKEITQHQ*LVIIFSPSLSILQWKEWRKHF
K*PSTTTEDLSHPCSHSHNHL*ETQGGLSHTWI
LLFFLTPK*YKRLMNSG*K*LRERLGEWGDDDDG
QRVQNLTQD*GRRIGYRDRDLRMTWTHSLALKS
LNTGL*LVHSRTFICIRYQTTSASDWPWARPAL
WPMIGSFQDIHLHKESNHTSLGLAVSQFTSVSNW
L*VSLSFT*GVTIKKPLQGT*APEDFATRALEP
LALAHSHPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKLSHPGICAHH
WSGGIFWSWTK*HKQANSSGGPDREL*H*LPDFC
*RLRGCSSQTHFCWNICQLCDNSSVKLE*YFHL
LLV*LQVF*RKEELEKRLPLMWT*KWQEIPSRS
*QKRNGFLP**LRVSRMICSELFHAILHTKKLYQ
FSSCSQNVL*CMILRTGRTWWFHLQRLCVK*VN
NLCKS*VNKANCRLPENTFNINELSNLLNFYID
RGRQLFRDNHLIPAETPSPVIFSDFPFIFNSLSK
IKLLQADSHIKMQAGVQWCNLSSPQPLPPGFKR
FFCLSLPNVRKESIHAYA*NNSAKKG*ISSITQ
IYT*SQTKSPG*RCSASIKSS*SY*LLQSISG*I
Y**NLS*VWRG*FRVLPLYV*RDDQARIWNVHV
S*NGFLHVVSCQA*T*EEKIFPLWNAVWTLLIQ
FKCC*PSFPTGSV*KTSGPKAIIGRFKRTQSSVG
EEFARSSR*CC**HWRCALHTLFYTLGPK*C*L
NSKWDLHTCGPNQQERLCF*VY*LHFQRLCKSS
L*GISERIL*SL*EGDT*TFLP*RTNDSNHWKY*
L*LETV*TEFKV*ARIPKITSYYTVVLEGFPQT
NLG*KEKIPLFPYRT**AACKRHTENGNSISLS
*NFQ*KRSPNINNLS*YSLPP*VFYNGKNGGSTS
SSHQQQQRICLTHAHTVIITSERLRVGFLTLGS
FCSSLHLNNTRD**IVVRSS*GRDWGNGEMMMM
VKGCKISHKTEAGE*GTEIGI*G*LGHTPWH*RV
*TLACDWSIPGPSFA*GIKPHQPLIGHGPDLHS
GQ*LVHSRTFICIRSQTTPVLDWL*ANSPQSLI
GCESVFHLHRV*PSRNLYRVLKPQKILLPGLLSH
LL*PTPTLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTT
GQVVSFGHGPSDTSKPTHPEALTENFDISCLIS
AEDFVDVQVKHIFAGTYANFVTTHQ*N*NDIFIS
CLSDCKFFKEKRNWRNDFH*CGLRNGKRYLQEV
NKKGMDFFHDNYVSRG*SAQSSSMPFSTPRSFI
SFPPAPRMSCDA*F*ELEEPGGSICKGCV*NE*T
IFASPK*TKLTVDYQKILST*MNSPTY*TFI*I
EEDSSFGITT*YLQKPPVLLFSVIFHLSLIRYP
KLNYCKLIHI*RCRLEYNGAISAHHNLCLPGSSD
SSASASQMSEKKAYMLMHETILQKKDEFPPSPR
FILRVRRSRLVKDALRQLSQAEATDFCKVLVVE
FINEICPESGGVSSEFFHCMFEEMTKPEYGMFMY
PEMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFN
LNVANLPFPLALYKKLLDQKPSLEDLKELSPRL
GKSLQEVLDDAADDIGDALCIRFSIHWDQNDVDL
IPNGISIPVDQTNKRDYVSKYIDYIFNVSVKAV
YEEFQRGFYRVCEKEILRHFYPEELMTAIIGNT
DYDWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKL
TLDEKKKFLFFLTGRDRLHARGIQKMEIVFRCP
ETFSERDHPTSITCHNILSLPKYSTMERMEEAL
QVAINNNRGFVSPMLTQS*SPLRDSGWAFSHLDP
SVLPYT*IIQEINE*WLEVVEGEIGGMGR***W
SKGAKSHTRLRQENRVQR*GSKDDLDTLPGTEE
SEHWPVIGPFQDLHLHKVSNHISL*LAMGQTCTL
ANDWFIPGHSFA*GVKPHQSWIGCEPIHLSL*L
AVSQSFIYIGCNHQETSTGYLSPRRFCYQGS*A
TCSSPLPPCGMYFHFCCFTALCSNKSTPSPP

Sequence NM_017912

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTGGCATATGTGCACACCACT
GGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGCAAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTG
CTGAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTGACAACTCATCAGGATACTAGTTCCACACGTGCTCCCGG
GAAAACCCTGCCAGAAATAAGCCGAATTAGCCAGTCCATGGCAGAAAAATGGATAGCAGTGAAAAGAAGAAGTACTGAACATGAAATGGCTAAAAG
TGAA
ATTAGAATGATATTTTCATCTCCTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGG
CAAGAGATACCTTCAAGAAGTTAACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTC
TCCACACCAAGAAGCTTTATCAGTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAG
GCTGTGTGTGAAATGAGTAAACAATCTTTGCAAGTCCTAAAGAAGTGTTGGGCATTTTTGCAAGAATCTTCTCTGAATCCGCTGATCCAGATGCTTAAAG
CAGCCATCATCTCTCAGCTGCTTCATCAGACTAAAACCGAACAGGATCACTGTAATGTTAAAGCTCTTTTAGGAATGATGAAAGAACTGCATAAGGTAAA
CAAAGCTAACTGTCGACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATAGAGGAAGACAGCTCTTTCGGGAT
AACCACCTGATACCTGCAGAAACCCCCAGTCCTGTTATTTTCAGTGATTTTCCATTTATCTTTAATTCGCTATCCAAAATTAAATTATTGCAAGCTGATT
CACATATAAAGATGCAGATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGATTTAT
ACTTAGAGTCAGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAATTTATT
AATGAAATTTGTCCTGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTATCCTG
AAATGGGTTCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAATTTAAA
TGTTGCTAACCTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGGGGAAG
AGTTTGCAAGAAGTTCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTTAATTC
CAAATGGGATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTTTATGA
GGAATTTCAGAGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTGATTAT
GACTGGAAACAGTTTGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACTAACCT
TGGATGAAAAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCTGAAAC
TTTCAGTGAAAGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTCAAGTA
GCCATCAACAACAACAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCCTTCTG
TTCTTCCTTACACCTAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGGTCAAA
GGGTGCAAAATCTCACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGTCTGAA
CACTGGCCTGTGATTGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCTGGCCA
ATGATTGGTTCATTCCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTGGCTGT
GAGTCAGTCTTTCATTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCACTTGC
TCTAGCCCACTCCCACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F5 (forward primer)
  • refseq_HERC6.R4 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEVITPWHMCTPL
VRWYLLVMDQVTQASQLIRRP*QRTLTLAA*FL
LKTSWMFKSNTFLLEHMPTL*QLIRILVPHVLP
GKPCQK*AELASPWQKNG*Q*KEEVLNMKWLK
VK
LE*YFHLLLV*LQVF*RKEELEKRLPLMWT*KW
QEIPSRS*QKRNGFLP**LRVSRMICSELFHAI
LHTKKLYQFSSCSQNVL*CMILRTGRTWWFHLQR
LCVK*VNNLCKS*RSVGHFCKNLL*IR*SRCLK
QPSSLSCFIRLKPNRITVMLKLF*E**KNCIR*
TKLTVDYQKILST*MNSPTY*TFI*IEEDSSFGI
TT*YLQKPPVLLFSVIFHLSLIRYPKLNYCKLI
HI*RCRCQKRKHTCLCMKQFCKKRMNFLHHPDL
YLESDEVAWLKMLCVN*VKLKLLTSAKY*WLNLL
MKFVLSLEGLVQSSSTVCLKR*PSQNMECSCIL
KWVPACGFLPSLNLRRKDISSLECCVDSPYSI*
MLLTFLSHWLCIKNFWTKSHHWKI*KNSVLGWGR
VCKKF*MMLLMTLEMRSAYAFLYTGTKMMLT*F
QMGSPYLWTKPTRETMFLSILITFSTSL*KQFM
RNFREDFIESVRRRYLDISTLKN**QQSLEILIM
TGNSLNRIQSMSKDTKNHILLYSCFGRLSTN*P
WMKRKNSSFSLQDVIGCMQEAYRKWK*YFAVLK
LSVKEITQHQ*LVIIFSPSLSILQWKEWRKHFK*
PSTTTEDLSHPCSHSHNHL*ETQGGLSHTWILL
FFLTPK*YKRLMNSG*K*LRERLGEWGDDDDGQ
RVQNLTQD*GRRIGYRDRDLRMTWTHSLALKSLN
TGL*LVHSRTFICIRYQTTSASDWPWARPALWP
MIGSFQDIHLHKESNHTSLGLAVSQFTSVSNWL
*VSLSFT*GVTIKKPLQGT*APEDFATRALEPLA
LAHSHPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKLSHPGICAHH
WSGGIFWSWTK*HKQANSSGGPDREL*H*LPDFC
*RLRGCSSQTHFCWNICQLCDNSSGY*FHTCSR
ENPARNKPN*PVHGRKMDSSEKKKY*T*NG*K
*
N*NDIFISCLSDCKFFKEKRNWRNDFH*CGLRNG
KRYLQEVNKKGMDFFHDNYVSRG*SAQSSSMPF
STPRSFISFPPAPRMSCDA*F*ELEEPGGSICK
GCV*NE*TIFASPKEVLGIFARIFSESADPDA*S
SHHLSAASSD*NRTGSL*C*SSFRNDERTA*GK
QS*LSTTRKYFQHK*TLQLIKLLYR*RKTALSG
*PPDTCRNPQSCYFQ*FSIYL*FAIQN*IIAS*F
TYKDADVRKESIHAYA*NNSAKKG*ISSITQIY
T*SQTKSPG*RCSASIKSS*SY*LLQSISG*IY
**NLS*VWRG*FRVLPLYV*RDDQARIWNVHVS*
NGFLHVVSCQA*T*EEKIFPLWNAVWTLLIQFK
CC*PSFPTGSV*KTSGPKAIIGRFKRTQSSVGE
EFARSSR*CC**HWRCALHTLFYTLGPK*C*LNS
KWDLHTCGPNQQERLCF*VY*LHFQRLCKSSL*
GISERIL*SL*EGDT*TFLP*RTNDSNHWKY*L
*LETV*TEFKV*ARIPKITSYYTVVLEGFPQTNL
G*KEKIPLFPYRT**AACKRHTENGNSISLS*N
FQ*KRSPNINNLS*YSLPP*VFYNGKNGGSTSS
SHQQQQRICLTHAHTVIITSERLRVGFLTLGSFC
SSLHLNNTRD**IVVRSS*GRDWGNGEMMMMVK
GCKISHKTEAGE*GTEIGI*G*LGHTPWH*RV*
TLACDWSIPGPSFA*GIKPHQPLIGHGPDLHSGQ
*LVHSRTFICIRSQTTPVLDWL*ANSPQSLIGC
ESVFHLHRV*PSRNLYRVLKPQKILLPGLLSHL
L*PTPTLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTT
GQVVSFGHGPSDTSKPTHPEALTENFDISCLIS
AEDFVDVQVKHIFAGTYANFVTTHQDTSSTRAPG
KTLPEISRISQSMAEKWIAVKRRSTEHEMAKS
E
IRMIFSSPACLTASFLKKRGTGETTSIDVDLEM
ARDTFKKLTKKEWISSMITTCLEDDLLRALPCHS
PHQEALSVFLLLPECPVMHDSKNWKNLVVPFAK
AVCEMSKQSLQVLKKCWAFLQESSLNPLIQMLK
AAIISQLLHQTKTEQDHCNVKALLGMMKELHKVN
KANCRLPENTFNINELSNLLNFYIDRGRQLFRD
NHLIPAETPSPVIFSDFPFIFNSLSKIKLLQAD
SHIKMQMSEKKAYMLMHETILQKKDEFPPSPRFI
LRVRRSRLVKDALRQLSQAEATDFCKVLVVEFI
NEICPESGGVSSEFFHCMFEEMTKPEYGMFMYP
EMGSCMWFPAKPKPEKKRYFLFGMLCGLSLFNLN
VANLPFPLALYKKLLDQKPSLEDLKELSPRLGK
SLQEVLDDAADDIGDALCIRFSIHWDQNDVDLI
PNGISIPVDQTNKRDYVSKYIDYIFNVSVKAVYE
EFQRGFYRVCEKEILRHFYPEELMTAIIGNTDY
DWKQFEQNSKYEQGYQKSHPTIQLFWKAFHKLT
LDEKKKFLFFLTGRDRLHARGIQKMEIVFRCPET
FSERDHPTSITCHNILSLPKYSTMERMEEALQV
AINNNRGFVSPMLTQS*SPLRDSGWAFSHLDPS
VLPYT*IIQEINE*WLEVVEGEIGGMGR***WSK
GAKSHTRLRQENRVQR*GSKDDLDTLPGTEESE
HWPVIGPFQDLHLHKVSNHISL*LAMGQTCTLA
NDWFIPGHSFA*GVKPHQSWIGCEPIHLSL*LAV
SQSFIYIGCNHQETSTGYLSPRRFCYQGS*ATC
SSPLPPCGMYFHFCCFTALCSNKSTPSPP

Sequence NM_001013002

AGCACTTGAAGTTCAGGCAGCGAGAGTTGACATGGGGCCAGGGCTGCGCCCCTGGGGCGGGTTGAAGACAGGGTGAGTCTCTTGATATTCAGGAAATCAT
CGCGCACCCAGTCACCAGCGTTCGGGAGCCTGTCGCAGCGGGACCGACGGAATCCGGAGCAGGCGACAGGGCGCAGAAGCGGGATGTACTTCTGTTGGGG
CGCCGACTCCAGGGAGCTGCAGCGCCGGAGGACGGCGGGCAGCCCCGGGGCTGAGCTACTGCAGGCGGCCAGCGGGGAGCGCCACTCTCTGCTGCTGCTG
ACCAACCACAGGGTCCTCTCGTGCGGAGACAACAGCAGGGGTCAGCTGGGCCGCAGGGCGCGCAGCGCGGGGAGCTGCCAGAACCAATTCAGGCATTGGA
AACCCTAATTGTTGATCTCGTGAGCTGCGGGAAGGAGCACTCCCTGGCTGTGTGCCACAAAGGAAGGGTCTTCGCATGGGGAGCTGGTTCTGAAGGGCAG
CTGGGGATTGGAGAATTCAAGGAAATAAGTTTCACACCTAAGAAAATAATGACTCTGAATGATATAAAAATAATACAAGTTTCCTGTGGACACTACCACT
CCCTGGCATTATCAAAAGATAGCCAAGTGTTTTCGTGGGGAAAGAACAGCCATGGGCAGCTGGGCTTGGGGAAGGAGTTCCCCTCCCAAGCCAGCCCGCA
GAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTGTGGGACTTCGTTTGGCTGGGGA
AGTAACAGTGCCGGGCAGCTGGCCCTCAGTGGGCGTAATGTCCCAGTGCAAAGCAACAAGCCTCTCTCAGTCGGTGCACTGAAGAATCTAGGTGTGGTTT
ATATCAGCTGTGGTGATGCACACACTGCGGTGCTTACCCAGGACGGGAAAGTGTTCACATTTGGAGACAATCGCTCTGGACAGCTGGGATACAGCCCCAC
TCCTGAGAAGAGAGGTCCACAACTTGTGGAAAGAATTGATGGCCTAGTTTCGCAGATAGATTGTGGAAGTTATCACACCCTGGCATATGTGCACACCACT
GGTCAGGTGGTATCTTTTGGTCATGGACCAAGTGACACAAGCAAGCCAACTCATCCGGAGGCCCTGACAGAGAACTTTGACATTAGCTGCCTGATTTCTG
CTGAAGACTTCGTGGATGTTCAAGTCAAACACATTTTTGCTGGAACATATGCCAACTTTGTGACAACTCATCAGGATACTAGTTCCACACGTGCTCCCGG
GAAAACCCTGCCAGAAATAAGCCGAATTAGCCAGTCCATGGCAGAAAAATGGATAGCAGTGAAAAGAAGAAGTACTGAACATGAAATGGCTAAAAG
TGAA
ATTAGAATGATATTTTCATCTCCTGCTTGTCTGACTGCAAGTTTTTTAAAGAAAAGAGGAACTGGAGAAACGACTTCCATTGATGTGGACTTAGAAATGG
CAAGAGATACCTTCAAGAAGTTAACAAAAAAGGAATGGATTTCTTCCATGATAACTACGTGTCTCGAGGATGATCTGCTCAGAGCTCTTCCATGCCATTC
TCCACACCAAGAAGCTTTATCAGTTTTCCTCCTGCTCCCAGAATGTCCTGTGATGCATGATTCTAAGAACTGGAAGAACCTGGTGGTTCCATTTGCAAAG
GCTGTGTGTGAAATGAGTAAACAATCTTTGCAAGTCCTAAAGAAGTGTTGGGCATTTTTGCAAGAATCTTCTCTGAATCCGCTGATCCAGATGCTTAAAG
CAGCCATCATCTCTCAGCTGCTTCATCAGACTAAAACCGAACAGGATCACTGTAATGTTAAAGCTCTTTTAGGAATGATGAAAGAACTGCATAAGGTAAA
CAAAGCTAACTGTCGACTACCAGAAAATACTTTCAACATAAATGAACTCTCCAACTTATTAAACTTTTATATAGATAGAGGAAGACAGCTCTTTCGGGAT
AACCACCTGATGTCAGAAAAGAAAGCATACATGCTTATGCATGAAACAATTCTGCAAAAAAAGGATGAATTTCCTCCATCACCCAGATTTATACTTAGAG
TCAGACGAAGTCGCCTGGTTAAAGATGCTCTGCGTCAATTAAGTCAAGCTGAAGCTACTGACTTCTGCAAAGTATTAGTGGTTGAATTTATTAATGAAAT
TTGTCCTGAGTCTGGAGGGGTTAGTTCAGAGTTCTTCCACTGTATGTTTGAAGAGATGACCAAGCCAGAATATGGAATGTTCATGTATCCTGAAATGGGT
TCCTGCATGTGGTTTCCTGCCAAGCCTAAACCTGAGAAGAAAAGATATTTCCTCTTTGGAATGCTGTGTGGACTCTCCTTATTCAATTTAAATGTTGCTA
ACCTTCCTTTCCCACTGGCTCTGTATAAAAAACTTCTGGACCAAAAGCCATCATTGGAAGATTTAAAAGAACTCAGTCCTCGGTTGGGGAAGAGTTTGCA
AGAAGTTCTAGATGATGCTGCTGATGACATTGGAGATGCGCTCTGCATACGCTTTTCTATACACTGGGACCAAAATGATGTTGACTTAATTCCAAATGGG
ATCTCCATACCTGTGGACCAAACCAACAAGAGAGACTATGTTTCTAAGTATATTGATTACATTTTCAACGTCTCTGTAAAAGCAGTTTATGAGGAATTTC
AGAGAGGATTTTATAGAGTCTGTGAGAAGGAGATACTTAGACATTTCTACCCTGAAGAACTAATGACAGCAATCATTGGAAATACTGATTATGACTGGAA
ACAGTTTGAACAGAATTCAAAGTATGAGCAAGGATACCAAAAATCACATCCTACTATACAGTTGTTTTGGAAGGCTTTCCACAAACTAACCTTGGATGAA
AAGAAAAAATTCCTCTTTTTCCTTACAGGACGTGATAGGCTGCATGCAAGAGGCATACAGAAAATGGAAATAGTATTTCGCTGTCCTGAAACTTTCAGTG
AAAGAGATCACCCAACATCAATAACTTGTCATAATATTCTCTCCCTCCCTAAGTATTCTACAATGGAAAGAATGGAGGAAGCACTTCAAGTAGCCATCAA
CAACAACAGAGGATTTGTCTCACCCATGCTCACACAGTCATAATCACCTCTGAGAGACTCAGGGTGGGCTTTCTCACACTTGGATCCTTCTGTTCTTCCT
TACACCTAAATAATACAAGAGATTAATGAATAGTGGTTAGAAGTAGTTGAGGGAGAGATTGGGGGAATGGGGAGATGATGATGATGGTCAAAGGGTGCAA
AATCTCACACAAGACTGAGGCAGGAGAATAGGGTACAGAGATAGGGATCTAAGGATGACTTGGACACACTCCCTGGCACTGAAGAGTCTGAACACTGGCC
TGTGATTGGTCCATTCCAGGACCTTCATTTGCATAAGGTATCAAACCACATCAGCCTCTGATTGGCCATGGGCCAGACCTGCACTCTGGCCAATGATTGG
TTCATTCCAGGACATTCATTTGCATAAGGAGTCAAACCACACCAGTCTTGGATTGGCTGTGAGCCAATTCACCTCAGTCTCTAATTGGCTGTGAGTCAGT
CTTTCATTTACATAGGGTGTAACCATCAAGAAACCTCTACAGGGTACTTAAGCCCCAGAAGATTTTGCTACCAGGGCTCTTGAGCCACTTGCTCTAGCCC
ACTCCCACCCTGTGGAATGTACTTTCACTTTTGCTGCTTCACTGCCTTGTGCTCCAATAAATCCACTCCTTCACCACCCA
  • refseq_HERC6.F5 (forward primer)
  • refseq_HERC6.R4 (reverse primer)
  • Single exon skipping

Frame 0

ST*SSGSES*HGARAAPLGRVEDRVSLLIFRKS
SRTQSPAFGSLSQRDRRNPEQATGRRSGMYFCWG
ADSRELQRRRTAGSPGAELLQAASGERHSLLLL
TNHRVLSCGDNSRGQLGRRARSAGSCQNQFRHW
KP*LLIS*AAGRSTPWLCATKEGSSHGELVLKGS
WGLENSRK*VSHLRK**L*MI*K*YKFPVDTTT
PWHYQKIAKCFRGERTAMGSWAWGRSSPPKPAR
RG*GPWRGSHWLRWLPEGLTALPCLSVGLRLAGE
VTVPGSWPSVGVMSQCKATSLSQSVH*RI*VWF
ISAVVMHTLRCLPRTGKCSHLETIALDSWDTAP
LLRREVHNLWKELMA*FRR*IVEVITPWHMCTPL
VRWYLLVMDQVTQASQLIRRP*QRTLTLAA*FL
LKTSWMFKSNTFLLEHMPTL*QLIRILVPHVLP
GKPCQK*AELASPWQKNG*Q*KEEVLNMKWLK
VK
LE*YFHLLLV*LQVF*RKEELEKRLPLMWT*KW
QEIPSRS*QKRNGFLP**LRVSRMICSELFHAI
LHTKKLYQFSSCSQNVL*CMILRTGRTWWFHLQR
LCVK*VNNLCKS*RSVGHFCKNLL*IR*SRCLK
QPSSLSCFIRLKPNRITVMLKLF*E**KNCIR*
TKLTVDYQKILST*MNSPTY*TFI*IEEDSSFGI
TT*CQKRKHTCLCMKQFCKKRMNFLHHPDLYLE
SDEVAWLKMLCVN*VKLKLLTSAKY*WLNLLMK
FVLSLEGLVQSSSTVCLKR*PSQNMECSCILKWV
PACGFLPSLNLRRKDISSLECCVDSPYSI*MLL
TFLSHWLCIKNFWTKSHHWKI*KNSVLGWGRVC
KKF*MMLLMTLEMRSAYAFLYTGTKMMLT*FQMG
SPYLWTKPTRETMFLSILITFSTSL*KQFMRNF
REDFIESVRRRYLDISTLKN**QQSLEILIMTG
NSLNRIQSMSKDTKNHILLYSCFGRLSTN*PWMK
RKNSSFSLQDVIGCMQEAYRKWK*YFAVLKLSV
KEITQHQ*LVIIFSPSLSILQWKEWRKHFK*PS
TTTEDLSHPCSHSHNHL*ETQGGLSHTWILLFFL
TPK*YKRLMNSG*K*LRERLGEWGDDDDGQRVQ
NLTQD*GRRIGYRDRDLRMTWTHSLALKSLNTG
L*LVHSRTFICIRYQTTSASDWPWARPALWPMIG
SFQDIHLHKESNHTSLGLAVSQFTSVSNWL*VS
LSFT*GVTIKKPLQGT*APEDFATRALEPLALA
HSHPVECTFTFAASLPCAPINPLLHHP

Frame 1

ALEVQAARVDMGPGLRPWGGLKTG*VS*YSGNH
RAPSHQRSGACRSGTDGIRSRRQGAEAGCTSVG
APTPGSCSAGGRRAAPGLSYCRRPAGSATLCCC*
PTTGSSRAETTAGVSWAAGRAARGAARTNSGIG
NPNC*SRELREGALPGCVPQRKGLRMGSWF*RA
AGDWRIQGNKFHT*ENNDSE*YKNNTSFLWTLPL
PGIIKR*PSVFVGKEQPWAAGLGEGVPLPSQPA
EGEVPGGDPTGSGGCRRGSQLCPVSLWDFVWLG
K*QCRAAGPQWA*CPSAKQQASLSRCTEESRCGL
YQLW*CTHCGAYPGRESVHIWRQSLWTAGIQPH
S*EERSTTCGKN*WPSFADRLWKLSHPGICAHH
WSGGIFWSWTK*HKQANSSGGPDREL*H*LPDFC
*RLRGCSSQTHFCWNICQLCDNSSGY*FHTCSR
ENPARNKPN*PVHGRKMDSSEKKKY*T*NG*K
*
N*NDIFISCLSDCKFFKEKRNWRNDFH*CGLRNG
KRYLQEVNKKGMDFFHDNYVSRG*SAQSSSMPF
STPRSFISFPPAPRMSCDA*F*ELEEPGGSICK
GCV*NE*TIFASPKEVLGIFARIFSESADPDA*S
SHHLSAASSD*NRTGSL*C*SSFRNDERTA*GK
QS*LSTTRKYFQHK*TLQLIKLLYR*RKTALSG
*PPDVRKESIHAYA*NNSAKKG*ISSITQIYT*S
QTKSPG*RCSASIKSS*SY*LLQSISG*IY**N
LS*VWRG*FRVLPLYV*RDDQARIWNVHVS*NG
FLHVVSCQA*T*EEKIFPLWNAVWTLLIQFKCC*
PSFPTGSV*KTSGPKAIIGRFKRTQSSVGEEFA
RSSR*CC**HWRCALHTLFYTLGPK*C*LNSKW
DLHTCGPNQQERLCF*VY*LHFQRLCKSSL*GIS
ERIL*SL*EGDT*TFLP*RTNDSNHWKY*L*LE
TV*TEFKV*ARIPKITSYYTVVLEGFPQTNLG*
KEKIPLFPYRT**AACKRHTENGNSISLS*NFQ*
KRSPNINNLS*YSLPP*VFYNGKNGGSTSSSHQ
QQQRICLTHAHTVIITSERLRVGFLTLGSFCSS
LHLNNTRD**IVVRSS*GRDWGNGEMMMMVKGCK
ISHKTEAGE*GTEIGI*G*LGHTPWH*RV*TLA
CDWSIPGPSFA*GIKPHQPLIGHGPDLHSGQ*L
VHSRTFICIRSQTTPVLDWL*ANSPQSLIGCESV
FHLHRV*PSRNLYRVLKPQKILLPGLLSHLL*P
TPTLWNVLSLLLLHCLVLQ*IHSFTT

Frame 2

HLKFRQRELTWGQGCAPGAG*RQGESLDIQEII
AHPVTSVREPVAAGPTESGAGDRAQKRDVLLLG
RRLQGAAAPEDGGQPRG*ATAGGQRGAPLSAAA
DQPQGPLVRRQQQGSAGPQGAQRGELPEPIQALE
TLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQ
LGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYH
SLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQ
RVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWG
SNSAGQLALSGRNVPVQSNKPLSVGALKNLGVV
YISCGDAHTAVLTQDGKVFTFGDNRSGQLGYSPT
PEKRGPQLVERIDGLVSQIDCGSYHTLAYVHTT
GQVVSFGHGPSDTSKPTHPEALTENFDISCLIS
AEDFVDVQVKHIFAGTYANFVTTHQDTSSTRAPG
KTLPEISRISQSMAEKWIAVKRRSTEHEMAKS
E
IRMIFSSPACLTASFLKKRGTGETTSIDVDLEM
ARDTFKKLTKKEWISSMITTCLEDDLLRALPCHS
PHQEALSVFLLLPECPVMHDSKNWKNLVVPFAK
AVCEMSKQSLQVLKKCWAFLQESSLNPLIQMLK
AAIISQLLHQTKTEQDHCNVKALLGMMKELHKVN
KANCRLPENTFNINELSNLLNFYIDRGRQLFRD
NHLMSEKKAYMLMHETILQKKDEFPPSPRFILR
VRRSRLVKDALRQLSQAEATDFCKVLVVEFINEI
CPESGGVSSEFFHCMFEEMTKPEYGMFMYPEMG
SCMWFPAKPKPEKKRYFLFGMLCGLSLFNLNVA
NLPFPLALYKKLLDQKPSLEDLKELSPRLGKSLQ
EVLDDAADDIGDALCIRFSIHWDQNDVDLIPNG
ISIPVDQTNKRDYVSKYIDYIFNVSVKAVYEEF
QRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWK
QFEQNSKYEQGYQKSHPTIQLFWKAFHKLTLDE
KKKFLFFLTGRDRLHARGIQKMEIVFRCPETFS
ERDHPTSITCHNILSLPKYSTMERMEEALQVAIN
NNRGFVSPMLTQS*SPLRDSGWAFSHLDPSVLP
YT*IIQEINE*WLEVVEGEIGGMGR***WSKGA
KSHTRLRQENRVQR*GSKDDLDTLPGTEESEHWP
VIGPFQDLHLHKVSNHISL*LAMGQTCTLANDW
FIPGHSFA*GVKPHQSWIGCEPIHLSL*LAVSQ
SFIYIGCNHQETSTGYLSPRRFCYQGS*ATCSSP
LPPCGMYFHFCCFTALCSNKSTPSPP

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