Sequences - Rnomics 📊 Palace

        ☰
    
        Rnomics 📊 Palace
    
                       Back to Rnomics Platform
            
                       Open Session

1 warning:

Access restricted to public data.
Please sign in at Rnomics Platform to access your data.

Navigation

Home

Sequences

Sequence NM_172103

CCACGTGAAGTTGTCGCTGCCTTAGAGAGGGGGAAAGAGCTGCGGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTT CTTCTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCCTCGGAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCT TGTGTACGCTATTTGTTGTGGGGTGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACACTGGAAGGAACGAGAATA AATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACACTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGC TGCTTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGAT GTTTCACAATCTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCCAGGTAGCTCCAAACTGG AAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGTGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGC CACGACTGGAGATGGAGCGCTTGACACTTTTACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTATTCCCCACAGCTGTAT CCTTCCAAGCCCTATCCACACATTCTTTCTACACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGGGATGCAGCAGCCAGCCG TCTACACAGCCTACTCACAGACAGGACAGCCCTACAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCA AACTCAGTCCCCATTACAGAGTGGCTGCCTCAGTTACAGCCCAGGGTTCTCTACCCCACAGCCAGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCT AGTTTTGCACCATCATCTACTATTTATGCAAATAATTCAGTTTCCAATTCAACGAATTTCAGTGGTTCACAACAGGATTATCCATCCTATACAGCCTTTG GCCAAAACCAGTATGCACAGTATTATTCAGCATCAACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTCTACTTA TCAGTTGCAGGAATCTCTCCCAGGACTGACTAACCAACCAGGAGAGTTCGATACCATGCAGAGTCCCTCCACACCCATCAAAGATCTTGATGAGAGAACC TGTAGGAGTTCTGGGTCAAAGTCCAGAGGAAGAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGTGTTTGTCTGGGATTTGG ATGAAACCATCATTGTTTTTCACTCACTGCTCACCGGGTCTTATGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGA AGAAATGATTTTTAATCTTGCTGATACTCATTTGTTTTTTAATGATTTAGAGGAGTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGG CAGGACTTAAGTACCTACAGTTTTGCAACTGATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGTAAGAGGAGGGGTTGACT GGATGAGGAAGTTGGCTTTTCGTTACAGAAGAGTAAAAGAATTATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGC CTGGCTACAGTTAAGGGCAGAGATTGAAGGTCTGACAGATTCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTAGCACTAGGAGTAACTGCATA AATGTCTTGGTAACGACAACTCAACTGATCCCAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTTCCCCATTGAGAATATTTACAGTGCAA CTAAAATAGGAAAAGAAAGTTGCTTTGAACGAATAATGCAAAGGTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAGAAGAACAGGC AGCAAAAAAGCACAACATGCCCTTCTGGAGGATATCCAGTCACTCAGACCTCCTGGCTCTCCACCAAGCACTGGAATTAGAGTATTTGTAACTGTGTTCT TTAGCCGGAGATCCATTTTTTATATTTCAAGTACACTGAATTTTTATGTGTGATTCAATGCCTCTGGCTCTACACATATAAATTGTCTTAATGGATGAAA TCATATTTGGAATAAAAATTCCAGAATGAAGAATTCAGATTGCTGAATGGAGTTAAACTTTAGTGCTACAGAAAAGAAACTCTATGGTCTTATATTTACA ACACTTTAATGGGTTTTTTAAAAATCTGTGGAGGTTGCTGGTACACACCAAATGAGTCCAAACTGGAATGAGCAGCTTTAGCAAAGAACTCTTACCCTGG CAAAGCAGCAACACACATGCTCCGTCTGACAAGGTGGTCAACAACATTCCTCAAAATGGGAGATCTTCTCAGCCCTGAGGTTTGAATCTGACTTTAGCCT ACCTAACCCAGAAAATCTGAATTGGAATGCACTCAGACTGTATAAGGACAGTCCTATTTAGACATGTAATTTGTGTAAATTATTGATGAAAATAATTTAC TGTGACTTTATTAGCAGCTGACTTTCAAAGTGGATGCAATTTTTCTTTCTTTTGTTGGGGAGGGGAATGGGAGGGGAAATGGGAATATAATATTGTCTCT TTTTTAAGTTTGGCAAACAGAATGTTCATACTGATGTGTTGTGCCTTAAAGACAAGACAGCATTTGTGTGTTACAATGTAACTTTGGTTAAAATCTCTGT AGATAATG

refseq_EYA4.F1 (forward primer)
refseq_EYA4.R1 (reverse primer)
Single exon skipping

Frame 0

PREVVAALERGKELREKPGSDDCGGWARSLIFF SSPFPPVAVRSFGSSPFLLPLGAGFSLRPASPPL VYAICCGVAEGDVLFSPEAQREGETSTLEGTRI NT*LRTH*TAAGTDTSGTRGGPGDEIVIFT*RK LLLLGSGRRSEKTTWKTPRI*MNNQ*RKRAQNQM FHNLRIPGLWKCRT*QVLILLLEVVILQVAPNW KNLISAAHQLLQMGQECLFLQSKQSP*TAVKPQ PRLEMERLTLLLGQ*LQVVATAPDQHISIPHSCI LPSPIHTFFLHQQLKQCLPMQARLSIRGCSSQP STQPTHRQDSPTACPLTIWV*CCQPSRQRVDFP KLSPHYRVAASVTAQGSLPHSQARHLILTKCQVL VLHHHLLFMQIIQFPIQRISVVHNRIIHPIQPL AKTSMHSIIQHQRMERI*HRITQPMAHPLQPLL ISCRNLSQD*LTNQESSIPCRVPPHPSKILMREP VGVLGQSPEEEAGKIIPPRLLIVTWSVCLSGIW MKPSLFFTHCSPGLMHRSMARIPPWL*PLDSAW KK*FLILLILICFLMI*RSVIKFI*MMFPLMIMG RT*VPTVLQLMASMQLQVVQTFVCQQV*EEGLT G*GSWLFVTEE*KNYITPTRTTLEDSLALPRGM PGYS*GQRLKV*QIPG*QMHLSLYQLLALGVTA* MSW*RQLN*SQHLRRFYSIV*EVLSPLRIFTVQ LK*EKKVALNE*CKGLAEK*CML*LGMV*KKNR QQKSTTCPSGGYPVTQTSWLSTKHWN*SICNCVL *PEIHFLYFKYTEFLCVIQCLWLYTYKLS*WMK SYLE*KFQNEEFRLLNGVKL*CYRKETLWSYIY NTLMGFLKICGGCWYTPNESKLE*AALAKNSYPG KAATHMLRLTRWSTTFLKMGDLLSPEV*I*L*P T*PRKSELECTQTV*GQSYLDM*FV*IIDENNL L*LY*QLTFKVDAIFLSFVGEGNGRGNGNIILSL F*VWQTECSY*CVVP*RQDSICVLQCNFG*NLC R*

Frame 1

HVKLSLP*RGGKSCGKSRGVTTAAAGRALSFSF LLLSPLSQSGVLAPLLSSSPSEPASPSAPLLPR LCTLFVVGWPKGMSCFHQRHSAKGKLRHWKERE* ILNYGRTEPRLGQTLREPEADRATR*SFLLEGS CFYLGVAGEVRKPHGRLPGFK*TISKENVHRIR CFTISEFQVYGNAGPSKSSYSCWRW*YSR*LQTG KI*SQQHISYYKWDRSVSSCSQNRALEQQ*NHS HDWRWSA*HFYWVSNYK*WLQPQISTSVFPTAV SFQALSTHSFYTSSSNNVCLCRPDSVFGDAAASR LHSLLTDRTALQLAHLRFGCDVASHQDREWTFP NSVPITEWLPQLQPRVLYPTARPDTLFLPNARF *FCTIIYYLCK*FSFQFNEFQWFTTGLSILYSLW PKPVCTVLFSINVWSVYDIE*HSRWHTLFNLYL SVAGISPRTD*PTRRVRYHAESLHTHQRS**EN L*EFWVKVQRKRPEK*SLPAS***PGACVCLGFG *NHHCFSLTAHRVLCTEVWQGSPHGCNPWTPHG RNDF*SC*YSFVF**FRGV*SSSYR*CFL***W AGLKYLQFCN*WLPCSCK*CKPLFANRCKRRG*L DEEVGFSLQKSKRII*HLQEQRWRTPWPCQEGC LATVKGRD*RSDRFLANKCT*VFINY*H*E*LH KCLGNDNSTDPSTCEGSTL*FRRCFPH*EYLQCN *NRKRKLL*TNNAKVWQKSSVCCNWGWCRRRTG SKKAQHALLEDIQSLRPPGSPPSTGIRVFVTVF FSRRSIFYISSTLNFYV*FNASGSTHINCLNG*N HIWNKNSRMKNSDC*MELNFSATEKKLYGLIFT TL*WVF*KSVEVAGTHQMSPNWNEQL*QRTLTL AKQQHTCSV*QGGQQHSSKWEIFSALRFESDFSL PNPENLNWNALRLYKDSPI*TCNLCKLLMKIIY CDFISS*LSKWMQFFFLLLGRGMGGEMGI*YCL FFKFGKQNVHTDVLCLKDKTAFVCYNVTLVKISV DN

Frame 2

T*SCRCLREGERAAGKAGE*RLRRLGALSHFLF FSFPPCRSPEFWLLSFPPPPRSRLLPPPRFSPA CVRYLLWGGRRGCPVFTRGTARRGNFDTGRNEN KYLITDALNRGWDRHFGNPRRTGRRDSHFYLKEA ASTWEWQEK*ENHMEDSQDLNEQSVKKTCTESD VSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKL EKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTA TTGDGALDTFTGSVITSSGYSPRSAHQYSPQLY PSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPA VYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQ TQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGS SFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAF GQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTY QLQESLPGLTNQPGEFDTMQSPSTPIKDLDERT CRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDL DETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRME EMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG QDLSTYSFATDGFHAAASSANLCLPTGVRGGVD WMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDA WLQLRAEIEGLTDSWLTNALKSLSIISTRSNCI NVLVTTTQLIPALAKVLLYSLGGAFPIENIYSA TKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQA AKKHNMPFWRISSHSDLLALHQALELEYL*LCS LAGDPFFIFQVH*IFMCDSMPLALHI*IVLMDE IIFGIKIPE*RIQIAEWS*TLVLQKRNSMVLYLQ HFNGFFKNLWRLLVHTK*VQTGMSSFSKELLPW QSSNTHAPSDKVVNNIPQNGRSSQP*GLNLTLA YLTQKI*IGMHSDCIRTVLFRHVICVNY**K*FT VTLLAADFQSGCNFSFFCWGGEWEGKWEYNIVS FLSLANRMFILMCCALKTRQHLCVTM*LWLKSL *IM

Sequence NM_004100

CCACGTGAAGTTGTCGCTGCCTTAGAGAGGGGGAAAGAGCTGCGGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTT CTTCTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCCTCGGAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCT TGTGTACGCTATTTGTTGTGGGGTGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACACTGGAAGGAACGAGAATA AATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACACTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGC TGCTTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGAT GTTTCACAATCTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCCAGGTAGCTCCAAACTGG AAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGGGGAAAACATGACTGTTTTAAACACAGCAGACTGGTTGCTGAGTTGCAACAC CCCCTCTTCTGCAACAATGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGATGGAGCGCTTGACACTTTT ACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTA CACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGGGATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGCC CTACAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCAAACTCAGTCCCCATTACAGAGTGGCTGCCTC AGTTACAGCCCAGGGTTCTCTACCCCACAGCCAGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTATTTATGCAA ATAATTCAGTTTCCAATTCAACGAATTTCAGTGGTTCACAACAGGATTATCCATCCTATACAGCCTTTGGCCAAAACCAGTATGCACAGTATTATTCAGC ATCAACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTCTACTTATCAGTTGCAGGAATCTCTCCCAGGACTGACT AACCAACCAGGAGAGTTCGATACCATGCAGAGTCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAAGTCCAGAGGAA GAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGTGTTTGTCTGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCT CACCGGGTCTTATGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGAAGAAATGATTTTTAATCTTGCTGATACTCAT TTGTTTTTTAATGATTTAGAGGAGTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTACCTACAGTTTTGCAACTG ATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGTAAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAG AGTAAAAGAATTATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTGGCTACAGTTAAGGGCAGAGATTGAAGGT CTGACAGATTCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAATGTCTTGGTAACGACAACTCAACTGATCC CAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTTCCCCATTGAGAATATTTACAGTGCAACTAAAATAGGAAAAGAAAGTTGCTTTGAACG AATAATGCAAAGGTTTGGCAGAAAAGTAGTGTATGTTGTAATTGGGGATGGTGTAGAAGAAGAACAGGCAGCAAAAAAGCACAACATGCCCTTCTGGAGG ATATCCAGTCACTCAGACCTCCTGGCTCTCCACCAAGCACTGGAATTAGAGTATTTGTAACTGTGTTCTTTAGCCGGAGATCCATTTTTTATATTTCAAG TACACTGAATTTTTATGTGTGATTCAATGCCTCTGGCTCTACACATATAAATTGTCTTAATGGATGAAATCATATTTGGAATAAAAATTCCAGAATGAAG AATTCAGATTGCTGAATGGAGTTAAACTTTAGTGCTACAGAAAAGAAACTCTATGGTCTTATATTTACAACACTTTAATGGGTTTTTTAAAAATCTGTGG AGGTTGCTGGTACACACCAAATGAGTCCAAACTGGAATGAGCAGCTTTAGCAAAGAACTCTTACCCTGGCAAAGCAGCAACACACATGCTCCGTCTGACA AGGTGGTCAACAACATTCCTCAAAATGGGAGATCTTCTCAGCCCTGAGGTTTGAATCTGACTTTAGCCTACCTAACCCAGAAAATCTGAATTGGAATGCA CTCAGACTGTATAAGGACAGTCCTATTTAGACATGTAATTTGTGTAAATTATTGATGAAAATAATTTACTGTGACTTTATTAGCAGCTGACTTTCAAAGT GGATGCAATTTTTCTTTCTTTTGTTGGGGAGGGGAATGGGAGGGGAAATGGGAATATAATATTGTCTCTTTTTTAAGTTTGGCAAACAGAATGTTCATAC TGATGTGTTGTGCCTTAAAGACAAGACAGCATTTGTGTGTTACAATGTAACTTTGGTTAAAATCTCTGTAGATAATG

refseq_EYA4.F1 (forward primer)
refseq_EYA4.R1 (reverse primer)
Single exon skipping

Frame 0

PREVVAALERGKELREKPGSDDCGGWARSLIFF SSPFPPVAVRSFGSSPFLLPLGAGFSLRPASPPL VYAICCGVAEGDVLFSPEAQREGETSTLEGTRI NT*LRTH*TAAGTDTSGTRGGPGDEIVIFT*RK LLLLGSGRRSEKTTWKTPRI*MNNQ*RKRAQNQM FHNLRIPGLWKCRT*QVLILLLEVVILQVAPNW KNLISAAHQLLQMGQEGKT*LF*TQQTGC*VAT PPLLQQCLFLQSKQSP*TAVKPQPRLEMERLTLL LGQ*LQVVATAPDQHISIPHSCILPSPIHTFFL HQQLKQCLPMQARLSIRGCSSQPSTQPTHRQDS PTACPLTIWV*CCQPSRQRVDFPKLSPHYRVAAS VTAQGSLPHSQARHLILTKCQVLVLHHHLLFMQ IIQFPIQRISVVHNRIIHPIQPLAKTSMHSIIQ HQRMERI*HRITQPMAHPLQPLLISCRNLSQD*L TNQESSIPCRVPPHPSKILMREPVGVLGQSPEE EAGKIIPPRLLIVTWSVCLSGIWMKPSLFFTHC SPGLMHRSMARIPPWL*PLDSAWKK*FLILLILI CFLMI*RSVIKFI*MMFPLMIMGRT*VPTVLQL MASMQLQVVQTFVCQQV*EEGLTG*GSWLFVTE E*KNYITPTRTTLEDSLALPRGMPGYS*GQRLKV *QIPG*QMHLSLYQLLALGVTA*MSW*RQLN*S QHLRRFYSIV*EVLSPLRIFTVQLK*EKKVALN E*CKGLAEK*CML*LGMV*KKNRQQKSTTCPSGG YPVTQTSWLSTKHWN*SICNCVL*PEIHFLYFK YTEFLCVIQCLWLYTYKLS*WMKSYLE*KFQNE EFRLLNGVKL*CYRKETLWSYIYNTLMGFLKICG GCWYTPNESKLE*AALAKNSYPGKAATHMLRLT RWSTTFLKMGDLLSPEV*I*L*PT*PRKSELEC TQTV*GQSYLDM*FV*IIDENNLL*LY*QLTFKV DAIFLSFVGEGNGRGNGNIILSLF*VWQTECSY *CVVP*RQDSICVLQCNFG*NLCR*

Frame 1

HVKLSLP*RGGKSCGKSRGVTTAAAGRALSFSF LLLSPLSQSGVLAPLLSSSPSEPASPSAPLLPR LCTLFVVGWPKGMSCFHQRHSAKGKLRHWKERE* ILNYGRTEPRLGQTLREPEADRATR*SFLLEGS CFYLGVAGEVRKPHGRLPGFK*TISKENVHRIR CFTISEFQVYGNAGPSKSSYSCWRW*YSR*LQTG KI*SQQHISYYKWDRRGKHDCFKHSRLVAELQH PLFCNNVSSCSQNRALEQQ*NHSHDWRWSA*HF YWVSNYK*WLQPQISTSVFPTAVSFQALSTHSFY TSSSNNVCLCRPDSVFGDAAASRLHSLLTDRTA LQLAHLRFGCDVASHQDREWTFPNSVPITEWLP QLQPRVLYPTARPDTLFLPNARF*FCTIIYYLCK *FSFQFNEFQWFTTGLSILYSLWPKPVCTVLFS INVWSVYDIE*HSRWHTLFNLYLSVAGISPRTD *PTRRVRYHAESLHTHQRS**ENL*EFWVKVQRK RPEK*SLPAS***PGACVCLGFG*NHHCFSLTA HRVLCTEVWQGSPHGCNPWTPHGRNDF*SC*YS FVF**FRGV*SSSYR*CFL***WAGLKYLQFCN* WLPCSCK*CKPLFANRCKRRG*LDEEVGFSLQK SKRII*HLQEQRWRTPWPCQEGCLATVKGRD*R SDRFLANKCT*VFINY*H*E*LHKCLGNDNSTDP STCEGSTL*FRRCFPH*EYLQCN*NRKRKLL*T NNAKVWQKSSVCCNWGWCRRRTGSKKAQHALLE DIQSLRPPGSPPSTGIRVFVTVFFSRRSIFYISS TLNFYV*FNASGSTHINCLNG*NHIWNKNSRMK NSDC*MELNFSATEKKLYGLIFTTL*WVF*KSV EVAGTHQMSPNWNEQL*QRTLTLAKQQHTCSV*Q GGQQHSSKWEIFSALRFESDFSLPNPENLNWNA LRLYKDSPI*TCNLCKLLMKIIYCDFISS*LSK WMQFFFLLLGRGMGGEMGI*YCLFFKFGKQNVHT DVLCLKDKTAFVCYNVTLVKISVDN

Frame 2

T*SCRCLREGERAAGKAGE*RLRRLGALSHFLF FSFPPCRSPEFWLLSFPPPPRSRLLPPPRFSPA CVRYLLWGGRRGCPVFTRGTARRGNFDTGRNEN KYLITDALNRGWDRHFGNPRRTGRRDSHFYLKEA ASTWEWQEK*ENHMEDSQDLNEQSVKKTCTESD VSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKL EKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNT PSSATMSLLAVKTEPLNSSETTATTGDGALDTF TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILS TPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCL SYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA STYGAYMTSNNTADGTPSSTSTYQLQESLPGLT NQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRG RGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLL TGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFAT DGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRR VKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEG LTDSWLTNALKSLSIISTRSNCINVLVTTTQLI PALAKVLLYSLGGAFPIENIYSATKIGKESCFER IMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWR ISSHSDLLALHQALELEYL*LCSLAGDPFFIFQ VH*IFMCDSMPLALHI*IVLMDEIIFGIKIPE*R IQIAEWS*TLVLQKRNSMVLYLQHFNGFFKNLW RLLVHTK*VQTGMSSFSKELLPWQSSNTHAPSD KVVNNIPQNGRSSQP*GLNLTLAYLTQKI*IGMH SDCIRTVLFRHVICVNY**K*FTVTLLAADFQS GCNFSFFCWGGEWEGKWEYNIVSFLSLANRMFI LMCCALKTRQHLCVTM*LWLKSL*IM

Sequence NM_172105

CCACGTGAAGTTGTCGCTGCCTTAGAGAGGGGGAAAGAGCTGCGGGAAAAGCCGGGGAGTGACGACTGCGGCGGCTGGGCGCGCTCTCTCATTTTCTTTT CTTCTCCTTTCCCCCCTGTCGCAGTCCGGAGTTTTGGCTCCTCTCCTTTCCTCCTCCCCCTCGGAGCCGGCTTCTCCCTCCGCCCCGCTTCTCCCCCGCT TGTGTACGCTATTTGTTGTGGGGTGGCCGAAGGGGATGTCCTGTTTTCACCAGAGGCACAGCGCGAAGGGGAAACTTCGACACTGGAAGGAACGAGAATA AATACTTAATTACGGACGCACTGAACCGCGGCTGGGACAGACACTTCGGGAACCCGAGGCGGACCGGGCGACGAGATAGTCATTTTTACTTGAAGGAAGC TGCTTCTACTTGGGAGTGGCAGGAGAAGTGAGAAAACCACATGGAAGACTCCCAGGATTTAAATGAACAATCAGTAAAGAAAACGTGCACAGAATCAGAT GTTTCACAATCTCAGAATTCCAGGTCTATGGAAATGCAGGACCTAGCAAGTCCTCATACTCTTGTTGGAGGTGGTGATACTCCAGGTAGCTCCAAACTGG AAAAATCTAATCTCAGCAGCACATCAGTTACTACAAATGGGACAGGAGGGGAAAACATGACTGTTTTAAACACAGCAGACTGGTTGCTGAGTTGCAACAC CCCCTCTTCTGCAACAATGTCTCTTCTTGCAGTCAAAACAGAGCCCTTGAACAGCAGTGAAACCACAGCCACGACTGGAGATGGAGCGCTTGACACTTTT ACTGGGTCAGTAATTACAAGTAGTGGCTACAGCCCCAGATCAGCACATCAGTATTCCCCACAGCTGTATCCTTCCAAGCCCTATCCACACATTCTTTCTA CACCAGCAGCTCAAACAATGTCTGCCTATGCAGGCCAGACTCAGTATTCGGGGATGCAGCAGCCAGCCGTCTACACAGCCTACTCACAGACAGGACAGCC CTACAGCTTGCCCACTTACGATTTGGGTGTGATGTTGCCAGCCATCAAGACAGAGAGTGGACTTTCCCAAACTCAGTCCCCATTACAGAGTGGCTGCCTC AGTTACAGCCCAGGGTTCTCTACCCCACAGCCAGGCCAGACACCTTATTCTTACCAAATGCCAGGTTCTAGTTTTGCACCATCATCTACTATTTATGCAA ATAATTCAGTTTCCAATTCAACGAATTTCAGTGGTTCACAACAGGATTATCCATCCTATACAGCCTTTGGCCAAAACCAGTATGCACAGTATTATTCAGC ATCAACGTATGGAGCGTATATGACATCGAATAACACAGCCGATGGCACACCCTCTTCAACCTCTACTTATCAGTTGCAGGAATCTCTCCCAGGACTGACT AACCAACCAGGAGAGTTCGATACCATGCAGAGTCCCTCCACACCCATCAAAGATCTTGATGAGAGAACCTGTAGGAGTTCTGGGTCAAAGTCCAGAGGAA GAGGCCGGAAAAATAATCCCTCCCCGCCTCCTGATAGTGACCTGGAGCGTGTGTTTGTCTGGGATTTGGATGAAACCATCATTGTTTTTCACTCACTGCT CACCGGGTCTTATGCACAGAAGTATGGCAAGGATCCCCCCATGGCTGTAACCCTTGGACTCCGCATGGAAGAAATGATTTTTAATCTTGCTGATACTCAT TTGTTTTTTAATGATTTAGAGGAGTGTGATCAAGTTCATATAGATGATGTTTCCTCTGATGATAATGGGCAGGACTTAAGTACCTACAGTTTTGCAACTG ATGGCTTCCATGCAGCTGCAAGTAGTGCAAACCTTTGTTTGCCAACAGGTGTAAGAGGAGGGGTTGACTGGATGAGGAAGTTGGCTTTTCGTTACAGAAG AGTAAAAGAATTATATAACACCTACAAGAACAACGTTGGAGGACTCCTTGGCCCTGCCAAGAGGGATGCCTGGCTACAGTTAAGGGCAGAGATTGAAGGT CTGACAGATTCCTGGCTAACAAATGCACTTAAGTCTTTATCAATTATTAGCACTAGGAGTAACTGCATAAATGTCTTGGTAACGACAACTCAACTGATCC CAGCACTTGCGAAGGTTCTACTCTATAGTTTAGGAGGTGCTTTCCCCATTGAGAATATTTACAGTGCAACTAAAATAGGCAAGGAAAGCTGTTTTGAGCG TATAGTGTCCAGATTTGGCACTAACATAACTTATGTTGTGATTGGAGATGGCCGAGATGAGGAGCATGCCGCTAACCAGCACAACATGCCCTTCTGGAGG ATATCCAGTCACTCAGACCTCCTGGCTCTCCACCAAGCACTGGAATTAGAGTATTTGTAACTGTGTTCTTTAGCCGGAGATCCATTTTTTATATTTCAAG TACACTGAATTTTTATGTGTGATTCAATGCCTCTGGCTCTACACATATAAATTGTCTTAATGGATGAAATCATATTTGGAATAAAAATTCCAGAATGAAG AATTCAGATTGCTGAATGGAGTTAAACTTTAGTGCTACAGAAAAGAAACTCTATGGTCTTATATTTACAACACTTTAATGGGTTTTTTAAAAATCTGTGG AGGTTGCTGGTACACACCAAATGAGTCCAAACTGGAATGAGCAGCTTTAGCAAAGAACTCTTACCCTGGCAAAGCAGCAACACACATGCTCCGTCTGACA AGGTGGTCAACAACATTCCTCAAAATGGGAGATCTTCTCAGCCCTGAGGTTTGAATCTGACTTTAGCCTACCTAACCCAGAAAATCTGAATTGGAATGCA CTCAGACTGTATAAGGACAGTCCTATTTAGACATGTAATTTGTGTAAATTATTGATGAAAATAATTTACTGTGACTTTATTAGCAGCTGACTTTCAAAGT GGATGCAATTTTTCTTTCTTTTGTTGGGGAGGGGAATGGGAGGGGAAATGGGAATATAATATTGTCTCTTTTTTAAGTTTGGCAAACAGAATGTTCATAC TGATGTGTTGTGCCTTAAAGACAAGACAGCATTTGTGTGTTACAATGTAACTTTGGTTAAAATCTCTGTAGATAATG

refseq_EYA4.F1 (forward primer)
refseq_EYA4.R1 (reverse primer)
Single exon skipping

Frame 0

PREVVAALERGKELREKPGSDDCGGWARSLIFF SSPFPPVAVRSFGSSPFLLPLGAGFSLRPASPPL VYAICCGVAEGDVLFSPEAQREGETSTLEGTRI NT*LRTH*TAAGTDTSGTRGGPGDEIVIFT*RK LLLLGSGRRSEKTTWKTPRI*MNNQ*RKRAQNQM FHNLRIPGLWKCRT*QVLILLLEVVILQVAPNW KNLISAAHQLLQMGQEGKT*LF*TQQTGC*VAT PPLLQQCLFLQSKQSP*TAVKPQPRLEMERLTLL LGQ*LQVVATAPDQHISIPHSCILPSPIHTFFL HQQLKQCLPMQARLSIRGCSSQPSTQPTHRQDS PTACPLTIWV*CCQPSRQRVDFPKLSPHYRVAAS VTAQGSLPHSQARHLILTKCQVLVLHHHLLFMQ IIQFPIQRISVVHNRIIHPIQPLAKTSMHSIIQ HQRMERI*HRITQPMAHPLQPLLISCRNLSQD*L TNQESSIPCRVPPHPSKILMREPVGVLGQSPEE EAGKIIPPRLLIVTWSVCLSGIWMKPSLFFTHC SPGLMHRSMARIPPWL*PLDSAWKK*FLILLILI CFLMI*RSVIKFI*MMFPLMIMGRT*VPTVLQL MASMQLQVVQTFVCQQV*EEGLTG*GSWLFVTE E*KNYITPTRTTLEDSLALPRGMPGYS*GQRLKV *QIPG*QMHLSLYQLLALGVTA*MSW*RQLN*S QHLRRFYSIV*EVLSPLRIFTVQLK*ARKAVLS V*CPDLALT*LML*LEMAEMRSMPLTSTTCPSGG YPVTQTSWLSTKHWN*SICNCVL*PEIHFLYFK YTEFLCVIQCLWLYTYKLS*WMKSYLE*KFQNE EFRLLNGVKL*CYRKETLWSYIYNTLMGFLKICG GCWYTPNESKLE*AALAKNSYPGKAATHMLRLT RWSTTFLKMGDLLSPEV*I*L*PT*PRKSELEC TQTV*GQSYLDM*FV*IIDENNLL*LY*QLTFKV DAIFLSFVGEGNGRGNGNIILSLF*VWQTECSY *CVVP*RQDSICVLQCNFG*NLCR*

Frame 1

HVKLSLP*RGGKSCGKSRGVTTAAAGRALSFSF LLLSPLSQSGVLAPLLSSSPSEPASPSAPLLPR LCTLFVVGWPKGMSCFHQRHSAKGKLRHWKERE* ILNYGRTEPRLGQTLREPEADRATR*SFLLEGS CFYLGVAGEVRKPHGRLPGFK*TISKENVHRIR CFTISEFQVYGNAGPSKSSYSCWRW*YSR*LQTG KI*SQQHISYYKWDRRGKHDCFKHSRLVAELQH PLFCNNVSSCSQNRALEQQ*NHSHDWRWSA*HF YWVSNYK*WLQPQISTSVFPTAVSFQALSTHSFY TSSSNNVCLCRPDSVFGDAAASRLHSLLTDRTA LQLAHLRFGCDVASHQDREWTFPNSVPITEWLP QLQPRVLYPTARPDTLFLPNARF*FCTIIYYLCK *FSFQFNEFQWFTTGLSILYSLWPKPVCTVLFS INVWSVYDIE*HSRWHTLFNLYLSVAGISPRTD *PTRRVRYHAESLHTHQRS**ENL*EFWVKVQRK RPEK*SLPAS***PGACVCLGFG*NHHCFSLTA HRVLCTEVWQGSPHGCNPWTPHGRNDF*SC*YS FVF**FRGV*SSSYR*CFL***WAGLKYLQFCN* WLPCSCK*CKPLFANRCKRRG*LDEEVGFSLQK SKRII*HLQEQRWRTPWPCQEGCLATVKGRD*R SDRFLANKCT*VFINY*H*E*LHKCLGNDNSTDP STCEGSTL*FRRCFPH*EYLQCN*NRQGKLF*A YSVQIWH*HNLCCDWRWPR*GACR*PAQHALLE DIQSLRPPGSPPSTGIRVFVTVFFSRRSIFYISS TLNFYV*FNASGSTHINCLNG*NHIWNKNSRMK NSDC*MELNFSATEKKLYGLIFTTL*WVF*KSV EVAGTHQMSPNWNEQL*QRTLTLAKQQHTCSV*Q GGQQHSSKWEIFSALRFESDFSLPNPENLNWNA LRLYKDSPI*TCNLCKLLMKIIYCDFISS*LSK WMQFFFLLLGRGMGGEMGI*YCLFFKFGKQNVHT DVLCLKDKTAFVCYNVTLVKISVDN

Frame 2

T*SCRCLREGERAAGKAGE*RLRRLGALSHFLF FSFPPCRSPEFWLLSFPPPPRSRLLPPPRFSPA CVRYLLWGGRRGCPVFTRGTARRGNFDTGRNEN KYLITDALNRGWDRHFGNPRRTGRRDSHFYLKEA ASTWEWQEK*ENHMEDSQDLNEQSVKKTCTESD VSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKL EKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNT PSSATMSLLAVKTEPLNSSETTATTGDGALDTF TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILS TPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCL SYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA STYGAYMTSNNTADGTPSSTSTYQLQESLPGLT NQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRG RGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLL TGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFAT DGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRR VKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEG LTDSWLTNALKSLSIISTRSNCINVLVTTTQLI PALAKVLLYSLGGAFPIENIYSATKIGKESCFER IVSRFGTNITYVVIGDGRDEEHAANQHNMPFWR ISSHSDLLALHQALELEYL*LCSLAGDPFFIFQ VH*IFMCDSMPLALHI*IVLMDEIIFGIKIPE*R IQIAEWS*TLVLQKRNSMVLYLQHFNGFFKNLW RLLVHTK*VQTGMSSFSKELLPWQSSNTHAPSD KVVNNIPQNGRSSQP*GLNLTLAYLTQKI*IGMH SDCIRTVLFRHVICVNY**K*FTVTLLAADFQS GCNFSFFCWGGEWEGKWEYNIVSFLSLANRMFI LMCCALKTRQHLCVTM*LWLKSL*IM