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Sequences

Sequence NM_007367

CGCGCGAGCGGCGCCAGCTCGGGGCAGCGGAACCCAGAGAAGCTGAGGGGGCGGTAGCGGCGGCGACGGCGACGACGACGACTCCCGCGCGTGTGCCCAG
CCTCTTCCCGCCGCAGCCGCCCTTTTCCTCCCTCCCTTACGTCCCCGAGTGCGGCAGTACCGCCTCCTTCCCAGCCGCGCGGCTTCCTCCAGACCTCTCG
GCGCGGGTGAGCCCTATTCCCAGAGGCAGGTGGTGCTGACCCTGTAACCCAAAGGAGGAAACAGCTGGCTAAGCTCATCATTGTTACTGGTGGGCACCAT
GTCCTTGAAGCTTCAGGCAAGCAATGTAACCAACAAGAATGACCCCAAGTCCATCAACTCTCGAGTCTTCATTGGAAACCTCAACACAGCTCTGGTGAAG
AAATCAGATGTGGAGACCATCTTCTCTAAGTATGGCCGTGTGGCCGGCTGTTCTGTGCACAAGGGCTATGCCTTTGTTCAGTACTCCAATGAGCGCCATG
CCCGGGCAGCTGTGCTGGGAGAGAATGGGCGGGTGCTGGCCGGGCAGACCCTGGACATCAACATGGCTGGAGAGCCTAAGCCTGACAGACCCAAGGGGCT
AAAGAGAGCAGCATCTGCCATATACAGGCTCTTCGACTACCGGGGCCGTCTGTCGCCCGTGCCAGTGCCCAGGGCGGTCCCTGTGAAGCGACCCCGGGTC
ACAGTCCCTTTGGTCCGGCGTGTCAAAACTAACGTACCTGTCAAGCTCTTTGCCCGCTCCACAGCTGTCACCACCAGCTCAGCCAAGATCAAGTTAAAGA
GCAGTGAGCTGCAGGCCATCAAGACGGAGCTGACACAGATCAAGTCCAATATCGATGCCCTGCTGAGCCGCTTGGAGCAGATCGCTGCGGAGCAAAAGGC
CAATCCAGATGGCAAGAAGAAGGGTGATGGAGGTGGCGCCGGCGGCGGCGGCGGTGGTGGTGGCAGCGGTGGCGGTGGCAGTGGTGGTGGCGGTGGCGGT
GGCAGCAGCCGGCCACCAGCCCCCCAAGAGAACACAACTTCTGAGGCAGGCCTGCCCCAGGGGGAAGCACGGACCCGAGACGACGGCGATGAGGAAGGGC
TCCTGACACACAGCGAGGAAGAGCTGGAACACAGCCAGGACACAGACGCGGATGATGGGGCCTTGCAGTAAGCAGCCTGACAGGAGCAATGGCCACCAGC
AGGTGAAGGGCATCGCTGCCCCAGGCCTCAAGCCGGGCACCCAACCCTGGATGCCACCCCCCAGCGGGTACCAGAGGAAAGCTGGCAGCAGGCGCCTCCT
CCCCCAACGCATCCCAGCCAGTGCCATGTCCTCTGCAGGTGGAGTTACTGGCCTACTCCTTCCCCATGAGCCCTCCCTGTCTGCACTGCCCAGGCCAGAG
GGTAGAGCACAGGGGTTTCCCCATACTACCTCCCCTCCCCAGGACACTCCCAGGCTTGGGTTTTTTCTATAGGTTTGGCGGGGGGCCACAGGGAGGGGAC
CCTGACAATAAAGAGATTGGATCCCAA
  • refseq_RALY.F2 (forward primer)
  • refseq_RALY.R2 (reverse primer)
  • Single exon skipping

Frame 0

RASGASSGQRNPEKLRGR*RRRRRRRRLPRVCP
ASSRRSRPFPPSLTSPSAAVPPPSQPRGFLQTSR
RG*ALFPEAGGADPVTQRRKQLAKLIIVTGGHH
VLEASGKQCNQQE*PQVHQLSSLHWKPQHSSGE
EIRCGDHLL*VWPCGRLFCAQGLCLCSVLQ*APC
PGSCAGREWAGAGRADPGHQHGWRA*A*QTQGA
KESSICHIQALRLPGPSVARASAQGGPCEATPG
HSPFGPACQN*RTCQALCPLHSCHHQLSQDQVKE
Q*AAGHQDGADTDQVQYRCPAEPLGADRCGAKG
QSRWQEEG*WRWRRRRRRWWWQRWRWQWWWRWR
WQQPATSPPREHNF*GRPAPGGSTDPRRRR*GRA
PDTQRGRAGTQPGHRRG*WGLAVSSLTGAMATS
R*RASLPQASSRAPNPGCHPPAGTRGKLAAGAS
SPNASQPVPCPLQVELLAYSFPMSPPCLHCPGQR
VEHRGFPILPPLPRTLPGLGFFYRFGGGPQGGD
PDNKEIGSQ

Frame 1

ARAAPARGSGTQRS*GGGSGGDGDDDDSRACAQ
PLPAAAALFLPPLRPRVRQYRLLPSRAASSRPL
GAGEPYSQRQVVLTL*PKGGNSWLSSSLLLVGTM
SLKLQASNVTNKNDPKSINSRVFIGNLNTALVK
KSDVETIFSKYGRVAGCSVHKGYAFVQYSNERH
ARAAVLGENGRVLAGQTLDINMAGEPKPDRPKGL
KRAASAIYRLFDYRGRLSPVPVPRAVPVKRPRV
TVPLVRRVKTNVPVKLFARSTAVTTSSAKIKLK
SSELQAIKTELTQIKSNIDALLSRLEQIAAEQKA
NPDGKKKGDGGGAGGGGGGGGSGGGGSGGGGGG
GSSRPPAPQENTTSEAGLPQGEARTRDDGDEEG
LLTHSEEELEHSQDTDADDGALQ*AA*QEQWPPA
GEGHRCPRPQAGHPTLDATPQRVPEESWQQAPP
PPTHPSQCHVLCRWSYWPTPSP*ALPVCTAQAR
G*STGVSPYYLPSPGHSQAWVFSIGLAGGHREGT
LTIKRLDP

Frame 2

RERRQLGAAEPREAEGAVAAATATTTTPARVPS
LFPPQPPFSSLPYVPECGSTASFPAARLPPDLS
ARVSPIPRGRWC*PCNPKEETAG*AHHCYWWAP
CP*SFRQAM*PTRMTPSPSTLESSLETSTQLW*R
NQMWRPSSLSMAVWPAVLCTRAMPLFSTPMSAM
PGQLCWERMGGCWPGRPWTSTWLESLSLTDPRG
*REQHLPYTGSSTTGAVCRPCQCPGRSL*SDPGS
QSLWSGVSKLTYLSSSLPAPQLSPPAQPRSS*R
AVSCRPSRRS*HRSSPISMPC*AAWSRSLRSKR
PIQMARRRVMEVAPAAAAVVVAAVAVAVVVAVAV
AAAGHQPPKRTQLLRQACPRGKHGPETTAMRKG
S*HTARKSWNTARTQTRMMGPCSKQPDRSNGHQ
QVKGIAAPGLKPGTQPWMPPPSGYQRKAGSRRLL
PQRIPASAMSSAGGVTGLLLPHEPSLSALPRPE
GRAQGFPHTTSPPQDTPRLGFFL*VWRGATGRG
P*Q*RDWIP

Sequence NM_016732

CGCGCGAGCGGCGCCAGCTCGGGGCAGCGGAACCCAGAGAAGCTGAGGGGGCGGTAGCGGCGGCGACGGCGACGACGACGACTCCCGCGCGTGTGCCCAG
CCTCTTCCCGCCGCAGCCGCCCTTTTCCTCCCTCCCTTACGTCCCCGAGTGCGGCAGTACCGCCTCCTTCCCAGCCGCGCGGCTTCCTCCAGACCTCTCG
GCGCGGGTGAGCCCTATTCCCAGAGGCAGGTGGTGCTGACCCTGTAACCCAAAGGAGGAAACAGCTGGCTAAGCTCATCATTGTTACTGGTGGGCACCAT
GTCCTTGAAGCTTCAGGCAAGCAATGTAACCAACAAGAATGACCCCAAGTCCATCAACTCTCGAGTCTTCATTGGAAACCTCAACACAGCTCTGGTGAAG
AAATCAGATGTGGAGACCATCTTCTCTAAGTATGGCCGTGTGGCCGGCTGTTCTGTGCACAAGGGCTATGCCTTTGTTCAGTACTCCAATGAGCGCCATG
CCCGGGCAGCTGTGCTGGGAGAGAATGGGCGGGTGCTGGCCGGGCAGACCCTGGACATCAACATGGCTGGAGAGCCTAAGCCTGACAGACCCAAGGGGCT
AAAGAGAGCAGCATCTGCCATATACAGTGGCTACATCTTTGACTATGATTACTACCGGGACGACTTCTACGACAGGCTCTTCGACTACCGGGGCCGTCTG
TCGCCCGTGCCAGTGCCCAGGGCGGTCCCTGTGAAGCGACCCCGGGTCACAGTCCCTTTGGTCCGGCGTGTCAAAACTAACGTACCTGTCAAGCTCTTTG
CCCGCTCCACAGCTGTCACCACCAGCTCAGCCAAGATCAAGTTAAAGAGCAGTGAGCTGCAGGCCATCAAGACGGAGCTGACACAGATCAAGTCCAATAT
CGATGCCCTGCTGAGCCGCTTGGAGCAGATCGCTGCGGAGCAAAAGGCCAATCCAGATGGCAAGAAGAAGGGTGATGGAGGTGGCGCCGGCGGCGGCGGC
GGTGGTGGTGGCAGCGGTGGCGGTGGCAGTGGTGGTGGCGGTGGCGGTGGCAGCAGCCGGCCACCAGCCCCCCAAGAGAACACAACTTCTGAGGCAGGCC
TGCCCCAGGGGGAAGCACGGACCCGAGACGACGGCGATGAGGAAGGGCTCCTGACACACAGCGAGGAAGAGCTGGAACACAGCCAGGACACAGACGCGGA
TGATGGGGCCTTGCAGTAAGCAGCCTGACAGGAGCAATGGCCACCAGCAGGTGAAGGGCATCGCTGCCCCAGGCCTCAAGCCGGGCACCCAACCCTGGAT
GCCACCCCCCAGCGGGTACCAGAGGAAAGCTGGCAGCAGGCGCCTCCTCCCCCAACGCATCCCAGCCAGTGCCATGTCCTCTGCAGGTGGAGTTACTGGC
CTACTCCTTCCCCATGAGCCCTCCCTGTCTGCACTGCCCAGGCCAGAGGGTAGAGCACAGGGGTTTCCCCATACTACCTCCCCTCCCCAGGACACTCCCA
GGCTTGGGTTTTTTCTATAGGTTTGGCGGGGGGCCACAGGGAGGGGACCCTGACAATAAAGAGATTGGATCCCAA
  • refseq_RALY.F2 (forward primer)
  • refseq_RALY.R2 (reverse primer)
  • Single exon skipping

Frame 0

RASGASSGQRNPEKLRGR*RRRRRRRRLPRVCP
ASSRRSRPFPPSLTSPSAAVPPPSQPRGFLQTSR
RG*ALFPEAGGADPVTQRRKQLAKLIIVTGGHH
VLEASGKQCNQQE*PQVHQLSSLHWKPQHSSGE
EIRCGDHLL*VWPCGRLFCAQGLCLCSVLQ*APC
PGSCAGREWAGAGRADPGHQHGWRA*A*QTQGA
KESSICHIQWLHL*L*LLPGRLLRQALRLPGPS
VARASAQGGPCEATPGHSPFGPACQN*RTCQALC
PLHSCHHQLSQDQVKEQ*AAGHQDGADTDQVQY
RCPAEPLGADRCGAKGQSRWQEEG*WRWRRRRR
RWWWQRWRWQWWWRWRWQQPATSPPREHNF*GRP
APGGSTDPRRRR*GRAPDTQRGRAGTQPGHRRG
*WGLAVSSLTGAMATSR*RASLPQASSRAPNPG
CHPPAGTRGKLAAGASSPNASQPVPCPLQVELLA
YSFPMSPPCLHCPGQRVEHRGFPILPPLPRTLP
GLGFFYRFGGGPQGGDPDNKEIGSQ

Frame 1

ARAAPARGSGTQRS*GGGSGGDGDDDDSRACAQ
PLPAAAALFLPPLRPRVRQYRLLPSRAASSRPL
GAGEPYSQRQVVLTL*PKGGNSWLSSSLLLVGTM
SLKLQASNVTNKNDPKSINSRVFIGNLNTALVK
KSDVETIFSKYGRVAGCSVHKGYAFVQYSNERH
ARAAVLGENGRVLAGQTLDINMAGEPKPDRPKGL
KRAASAIYSGYIFDYDYYRDDFYDRLFDYRGRL
SPVPVPRAVPVKRPRVTVPLVRRVKTNVPVKLF
ARSTAVTTSSAKIKLKSSELQAIKTELTQIKSNI
DALLSRLEQIAAEQKANPDGKKKGDGGGAGGGG
GGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAG
LPQGEARTRDDGDEEGLLTHSEEELEHSQDTDAD
DGALQ*AA*QEQWPPAGEGHRCPRPQAGHPTLD
ATPQRVPEESWQQAPPPPTHPSQCHVLCRWSYW
PTPSP*ALPVCTAQARG*STGVSPYYLPSPGHSQ
AWVFSIGLAGGHREGTLTIKRLDP

Frame 2

RERRQLGAAEPREAEGAVAAATATTTTPARVPS
LFPPQPPFSSLPYVPECGSTASFPAARLPPDLS
ARVSPIPRGRWC*PCNPKEETAG*AHHCYWWAP
CP*SFRQAM*PTRMTPSPSTLESSLETSTQLW*R
NQMWRPSSLSMAVWPAVLCTRAMPLFSTPMSAM
PGQLCWERMGGCWPGRPWTSTWLESLSLTDPRG
*REQHLPYTVATSLTMITTGTTSTTGSSTTGAVC
RPCQCPGRSL*SDPGSQSLWSGVSKLTYLSSSL
PAPQLSPPAQPRSS*RAVSCRPSRRS*HRSSPI
SMPC*AAWSRSLRSKRPIQMARRRVMEVAPAAAA
VVVAAVAVAVVVAVAVAAAGHQPPKRTQLLRQA
CPRGKHGPETTAMRKGS*HTARKSWNTARTQTR
MMGPCSKQPDRSNGHQQVKGIAAPGLKPGTQPWM
PPPSGYQRKAGSRRLLPQRIPASAMSSAGGVTG
LLLPHEPSLSALPRPEGRAQGFPHTTSPPQDTP
RLGFFL*VWRGATGRGP*Q*RDWIP

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