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Sequence NM_175625
GGTTACCTGGCGGCGGGCGGGCGCGGCCGGGAGCGGAGGGCCGCGGTCGCGAAGAGGATGAAGAGAGAGTTCCCGAACAAGTCGGAAGCAGCTCACAACACCGGACGCCGCGCGGCAGGGCTGTGGACCTGGGGTGGTTTCGTGTCCCAGTCTTAGGAAACTACGCGCGAGGCACCGTGCTGAGGCGTAGAGGTCACCCT
CGGGAGGTTTCGGTGAAACCTGGTGGGAAATTCCGGGCAGGCGCCCGGAGTCGCGCCCAAGTAGGCAGCTCCGTGCCGCCAGACTTGTGTTCGGGGGAGT
TGAGACGAACTGCACGGGTGGGATTGCATGGCTCTGCCCTCCCAGCGTTGACAACTCGCCCCGACCGCCCAGGAAGCGCGAGCTTACTGGCTCCAGAAGT
GATGATGCTGGGTGGAAGTCGCAGCATGTGAAGAGTTGCCGGTTGTTATGGGATTAAAAAAGATGAAAGGGTTATCTTATGATGAGGCTTTTGCTATGGC
TAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTGTATGAATCAGGAACTCAAGAGCAGACTACC
TCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGT
ATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATT
AACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTT
GGGTTGAGTACTGATAGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACTCGCAAAAGCTC
AGAGGGAACTGAAGTTAAAAGATGAAGAATGTGAGAGGCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCTAGTCTATTTGA
GGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAACAGCTAAAAGAAGCACAAGGAAAAATTGATGTACTTCAAGCTGAA
GTAGCTGCATTGAAGACACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAGACACCTTTTAAAAAGGGGCATACAA
GAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGTCATCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGACTTATCCTTGTA
TAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTCTTAGACAAAATCTACCAGGAAGATATCTTTCCATGTTTAACATTC
TCAAAAAGTGAGTTGGCTTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTACAACCTATCCGGTTTGTGAAAGCTT
CTGCAGTTGAATGCGGAGGACCAAAATCACTTCTGTATGTAACTTTTTTACATACATTCGATACATTCAGCAGGGACTCGTGAAACAGCAGGATGTTGAT
CAGATGTTTTGGGAGGTTATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTCTGATGCTCTGCGTGGGACCATGCCT
GAACTCCCCGAATAACTGAAAAATGGCTGAATATTTTTATGGTTACTTGATATTTATTTCCAAGGAGTGAGCCTAAGACTTTTTTCCCCTTTTGCAAATT
GCTCTAAGAAGTACCATGATTTCTTTTAAACTGATCTATGCTGTGTTTGCTTATTCTTTAGTTGAACACACTATGAAGAATTCCAGGTGTACTAGTGAAT
GTAATTTATAGTTGCCAAAAAAAAAAAAAACCTGAAATAAATAAATGTTAGATTGAATGTGTGTACATTTTCTCTTCTAGCTCTGACATGGCATTTAGGG
TTAGCAGAATGTATTAAATAGTAATTTTCAAACTACACAGTAGCTTCCTTCCTTGTGAGAGGCAAGAAAGAAGTCTGAGTGGATAGTACTCACTTTCCAA
GGCCCCCACCTCTAGAATGGCTTTATTTTTATCTGTTTTCTATATTGGGTTTCAAAAAAGATTTTATTTGAAGAAATACTTCTGCTGCTACAAAGTTTGA
AAGTTACTATTTTAATTATTCTGCTCTCTGTAACTGAAAGAATCCCTTTATTTTGGTTATTCATTAAAATATAATAGAAGGCAGTCAGATTTTATCCCAG
AGATGTATTCCTGAGTGTCTTGATATAGTGTATTCATGTTTTATATGTGTTGACCACTATATTGTCATTGGAGGGACATAGATGTAAATGAGTTTGACGT
GTGTCAAAGGGGTTTAAAGGGGTGTGGATTGAATGAATGGTACGTGCGAAGTATATGCTGATTATAGAACCACTTGATCTCTGCATTCCAAATTGTAAAA
CTGACTCAACTGGAGAAATTATAACAAAGAGGTTTGTGGTAGACATGTAATAAGTATAGAAAAGCAAAAAGAAAAGAGAAACTGCTTTAGTTTCTGTTTA
GAGAAAGCTGCTGTTAATATTTTTGGATAGTAGCCTTTCAGCTTTCAGATATTTTCTACTTACATATGCATATTTTTGAAACAAAAAGTAGGCTTTTTTT
TTGCTTTTTAAACCTAAACATTAAATATATTTTCCCTTGGGTAAACCTACACATCCTAATCCCTGTTTATAGAATTTTAACATAATTTAATTGTGTTTGG
AGATGAGGTGGTTTTCAGTTTATTTTTCATATTATAATGCTGTGACGAGTATCCTTATCTGTACACTTCTGAACATTGTGGAGTTCTTTCATGTGGATGC
CTGGAGATAAAATTGTGTCGAGATATATATGTATTTTTAAATGTTTGATCTGCATTGCTAGATTGCCATCCAGAAAAGTTAATCAATTTGTATTCACAGC
AGCAGTGTACAAGAGGGCTGGTTTTCTGAAGATAACATTTTTTTCAGTCCTGTTCAGAGGTTTGGTCAATCTTACCTGTAGATGACTTCAGCCACCAGGC
TGGATGGGAGCCCACAGACAAAAGGACATTGGTGTATGTTATGGTGAAAACCATCAGTACCATGCCTAGCTCAAGAATGTGAAATTGAACCTGAAAAAAA
CTTTGAACCTACAATTTTATGTTCTGAAAATAGTTATTCTAATGTGAGGGCATTAATAAGAATATGTACCATCAAAGCTTCAGAAGATTTTCCGTACAAA
CTAAAATCACTTTTGGAGAAAGTACCTAAATAAAAAGAGAAACAAATCCAGGAGATACTGTACGGTTTGAAAGAAAGGTAATCAAATACTCAGAAAAAGT
TTGTTGATGACTTAAAAAGGATAAATAAAAAGTAAGACTAAAGAAAATCAGTATACCCATTAATAATAAATCTTTAGTAATCTATAAGGGGAAGAATGCT
TTTCAACCTTATACACTAGAAGCATGCTCTTTAAAATTAATGCAACAGGATGACGACTTGATGTAGAAACTATATGTGGAATTATAGATTAAAATGTGAT
TGAAACATATTTAGAAAATGTGATTATCTTCCTGATCCTACTCCCTTTAGGAAGAACTTCTTAAACTGGAAGCAGGAAAAAAAAAAACCATAAAAGATAA
CCATAAAAGAATATAAGTTATGGTATATTATAAATTCTTAATTTAGAAATCGTGCATCAGTAGTTAGGCATTGTGGCTCATGCCTGTAATCCCAGCACTT
TGGGAGGCAGAGGCAGAAGGATTACTTGAGCTGCTTGAGCCCAGGAGTTTGAGACGGGCCTGGGAAAAATAGGGAAACTCCATTTACACACACACACACA
CACACACACACACACACACTGTGTCCATGAACTTGGGAGGATGAGGTGGGAGGATTGCTTGAGCCCAGGGGTTCAAGTCCAACTTGGGCAACATAGGGAG
ACCTTGTCTCTAAAAAAAAAACTAAAGCTAAACTACAAACTGTGAGGCAATATCTGCAACATTTATAACTAGTAATAGCTTAGTATCAAGAATGTATGCA
GAAATTCTACAAACCAACAAAAAAGGACAGTGTCACAGAAAAACAGGCAAAAGACTGAACCAGGCCTTCCACACAATTAGAAGTGCATGTGGGCCAATAA
ACATTAAGAGGTTTTCATCTCTCAATCAGGAAAACGTAAATCAAGATGACAATGACATGTTCAAATTCATTCGATTGGTGAAAATGAAGAAACACAAAGT
CAAGTTTTGGAGAGGGTTTTAGTCATTAGGATCACTCACATATTGCTGATGGGGGTATCAATTGGTATATCCACTGTGAAAAACCATTCACTAGAAAAGT
TGGGCCAGGCCCAGTGGCTCATGCCTCTTGGCTTTGGGAGGCCAAGGTAGGAGGATCACTTGAGCCCAAGAGTTCAAGACCAGCTTGAGCAACATAGGGA
GACCACATCTGCACAAAAAGATTTTTTTGAATTAGCTGGGCATGGTGGTGCATGCCTGTGGTCCCAGCTACTTGGGAAGCTGAGGTGGAAGGATTGCTTA
AGCCCAGGAGGTTGAGGCTGCAGTGAATCATGATTGTGCCACTGCACTCTTACCTTGGGTGACAGAGTAAGATCATACCTTAAAAAAAAAAAAAAAGTAT
ACCCATGGGTCAGCAATTTCACTTTTCAGTATATACTTGAGAAATGCTTGCACAGGTCCCCCAGATCACACATATAAGAATGTTCTGGAATAAATTAAAA
TGTCTATTTTTAGGAAGGTGTAATGTGTTCACAGAATGGGTGATTATTACATGGCAGCAAAATGAATGAATACCAGCTACTTGCAGCACAATAACTCAGA
ATGAAAAAGCAATTCTGAGAAAACTATATGTGACATGATACTTTTCTTATAAAAGTCAAGAACAACTAAAACTGAACAGCTGTTTAGGCATTGACATATG
TGACAAAACTTTTAAAAAGTAATAAAGTTCAAGATAGTGGTTACCTCTGGAGAGGTAGAGGAGGAGCAAATCTATGAGTAAGTCACTGGTAATGTTTTAG
TCCCTGGGTTAGGTGGTGGGTTTTGGGGTGGTTCATTTGTCATTAAAAGTAAGTACATGAGCTGGGTGTAGTGGTGCGTGCTTATAGTCCCAGCTACTTG
GGAGTCTGAGATAGGAAGATCCTTGAGGCCAGTTCAAGGCTATAGTGTGCTATGATTTCACCTGTGAATAGCTACTATATTCCAACCTGGGCAACGTAGA
CCTTGCCCCCCTTTAAAAAAATTCAAAAACAAAATAAATGCATGGACAAATGAATAAGAGAGTTATGCATGGAACATCGGTGGTGTATTATGAATCAAGC
ATTATTACTAGCTCAGTTATATGTGCCTTCATTCCAAAACAAAAAATAAAAGGTAAGAAAATTGTTGAATTGCATTTGAGAGAGAGGAAAGGAAAGAATT
CAGGTCTGAATCTTAGGCTTTTGGCTTGAGCTATTGCAGTTTATTGAGATGGGGAAATACATGGTGGGGAAAGTTTGGGTATGTGCATAACAGAGACAGA
AATTCAGTGTTTGACAGATCAAGTGTGAGGTGCCCACTGAGCATCAAAGTGGATATGTTAAGCAGGTATTGGATGTACAAATCTAAATTCAGTAAGGTCA
GTCCAGGAGAAAATTTGGGGAGTAGTTAGCCATGGGATCAGATGGGCGCTTTAGGGACACTTTGGAGATGAAGTACAGCACTGAGCCCTGAGTTCCTGTG
ACAGAGAAGCAGCCTGCAAAGACGAAAGGAGGAGCTGTTAGGAAGAGCAAGGCAACAGAAAAGGAAGAACCAGCATGCTGATTATGTTCAGGAGAGTGTT
TCTACGCTGAATTTAATTGCCAAGATTACCAATTCTAAAGAAGAGGAGGACTCTTGGACAAGTTTTTAGAAGTTGGTTTGGAGCTGGGGTGAGAGCCTGG
CCTAATGGAGACAGCTCTGGATTGGGAGTCACTTAGACCTACATTCTGGTCTAGGTTTGGCTCCCAAAAACTGGGAAGGTTAGTTAGGTGGCCACTCCTC
TCTCTTCATGGTCTCTCTCAGCTTGAAGACAATTTACAGTCTTTGACTAAGCATCCACACTGGAAGAACAAGATTTGGTTTCTGAACATTGGGTCTTAGT
CCTTAAAATAACTTGCAACCTGTTACGTCTTCACTTACTCCCATCGCCACCACAAGAATCCTGTGTGTTTTTGTTTTGTGCATCCAGTCTAAAACGGGTC
TGCTTTTATTCATAGGCTTTTGTTTTCAGTGGTTTTTGTTGTTGCATTTTTCCCTAGATAAAATGTTTTTTCTATAAGACACTGCTTAAAAGAGTCCAAT
GCAGTATGAATTTGTATTTGTGTTTAACTTTTGTGCTTAACAGATCTGCCATGGCTGAACTCTCAGTTGCTTAAGCAAAATTCTGGGGCTTATTCTAGGT
TCCTTTATTTGTCATTGTCACTCCCATTCCAGTTATCAGCAAATTCCATCAGCTGTCTCCGAGACATCTTAAATCTGTCTACCTCCCTCCATGTCCACTG
CTACCACTCTGCCCAAGCTATTATCATCTTTCACCTGAACTCCTGCACTAATGTCTGCTGTCCTTGCATCCACTCCTGCCCTCCTACAATCACTGACGGC
AGCCGCAGGGATCTTTATAAAACGAAAATCAGATAATGTCACTTCCCTGCTTAAAGCCCTTTGAGTGGCTTCCCATTGCACTTAGAAAAAAAAAAAAAAA
AAAAAACTGGCCAGGTGCGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCCCCTGAGGTTGGTAGTTCGAGACCTGCTTG
GCCAACATGGAGAAACCCTGTCTCTACTAAAAACACAAAATTAGTCAGGTGTGATGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGTCAGGAG
AAACGCTCGAACCCAGGAGGCAGAGGTTGTGGTGAGTTGACATCACGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTGAAAAAAAAAA
AAAAAAACCCAAACTCAATAGAAAATCAAGTTTTCATAGTGGTAGTTGTTAACAGAGAAATAACAATGAAAGCTTTAAAAAACTCCATGAAAATTTGCAA
AACTTAAAAAAAAAATGTAGAAGAGGACTAAACTTGATAAAATATTAAAAGAATTGAAACCCTTCCTAAAGGCAGCTTCTCAAGGGAGCACAAGTTCACA
CACAGTTTACTTTTGGAGGAACGTCTGAGGTCATGAGGACTAGATTCTAGAGCTACAGGTCTCAGGGACAGTCTCGAGGGATACAGGGCCCCCATCACCA
CATCCCCAGATTTAACCGCAGCAGCTCAGCTTTTATCTGTATCTGTTGGAGCTCTCTAGGAAATGTCAATACCAAAGCAAACCCAAATCACAACTAGATT
AGATTACTATTCAAGAGAATGATTCTCTACCGAAACTCTGCAAAATGGGGATATCAAGAGAGTTGGAAAATGTAAGACGTAAAGACCATAATCAGGAAAA
TACGCATCATATTTGTTATTCACTGAGAGGGAGGAATTTCCACTTAAATCCTATTTCCAGCAGCTGGATTGTGCTCTCAGTGGAGTGCTCTGGATTCTGA
TTAATAGAGATTTTCTAGTCCTCCCAGCAACTTCCTTCTCAATTCTCTTCACTTTCCGCAGATCTCGGCACCAGGGTTGCATCTTGTGGGCTCCATTGTG
TTTTCACACAATGTGCTATTTGTCCTTCACAGTGTTTTGGTTTATTTTTCTGTTTGTCCATCTTGTTTTTGAACAATTGCCAGCATTTAAAAATGAGGAA
ATCTAAAATCTGCATTTCAAGCTGCTCTTTTTTAAAATGTGCCGTTTCGACAACACTGAGCCCACAGTCTTGAATGACAACACTTGGGTGGAGCTGAGTG
ACTCCACCTGTCGGGTGGCTACACCCTTGCTCAGGGTATGCACTCCATGGTTTGCTCTATGGCCCACCATCCTGGATTGTCTCCCTGACACCAAGGCTAA
GGGACCCACTTTACTCACTTATCTGCTGGGCCTTGGAAGTATTTCAGTTCGGAACCCCAATTCTAACCTTAGCTTCTCAGGCCATTAAATGAAATCTCAT
TTCTATGATGCTTCCTGTCACATCACTGTGCTGCTGAGAACATGAAGTCTGTGGGTGAATTGGTGGACGGGATCCAGAATCATTACTTGGCAGTGGATTA
TAGTGTGATGACTCATTTCCGGTGGTCTCCAGGAGACTTGGCTGGGAGCTTCTCTTGGAGTCTAGGGTTAGCCAGAGGCTACATGTTTTAGGCATCTTAA
TTCATATTTTATCTAAAGGCATATAAATCCTTAAAAAAAATCATTTGACTTCATCCTTGCTCCCTACATCCAGCCAGTAACCATTGCTTTGTTTTACATC
GCGTGCTTCAGGCTTTACTACAGCCTACCTGGATTTTGCAGTAGCTTCTTAAACTGCTTAAACTTTGGATATTGCCCCAGCCAACACATTCTGCCACAGA
GATCTCTCTGAGTTAAATGGGATTGTATCATGCCCCACACCCAAGCAGATAGAAACTGTCAATAGATACACTTAGAATGAATATGCATGGAATCAAATTA
CATTCAGAATCTACCACTATAGGTAGTGAATACAACAGGATAGCAGAGGCTGGGAAGGGTAATGGGGGTTGGGGGGTGGGAGGATAAAGGGGTTGGGTAA
TGGGTGTAAAAATCTATAGAAGGAATATGATCTGTTGTTTGGTAGCACAATAGGGTAAATACAGTTAATAATTTATTGTATATTTCACAATAAAGGAGTG
GATTTGGAATGTTCTCAACACAAATGATAAATGTTTGAGGTGATGGATACCCCAATTACCCTGATTTGATCATTATACGTTGTATGTTTGTATCAAAATA
TCATATGTACCCCATAAATATGTACAACTATTATGTATCCATAAAAATTGGAAATAAACTACCACCATCTTTCTTCAGCCTATTTTCCTATCTCCTCTCG
CACCATACTAGGCACACAATCTCTGTACCTGTGCTGTCTTCCAAGCCATTGCTCATGTTTTAAGAAATATACTTATTGTTTAATATATCCTGTACCACTG
TAGGATGACTGTAGTTAACAATAATGTGTAGTTTCAAATAGCTAATAGCTGGAAGGAAGTTGTTGAATGTTTCCAACATAAAGAAATGATAAGTGTTTGA
GATGATGGATATGCTAATTACCCTGATCTGATCACTACACATTATATGTATGGAAATATCATTGTGTACCCCATGAATATGGGCAATTATTATTTGTTAA
TTAAAAAAATAAAAAAAAGACCCACCCACTGTTTAA
- refseq_RAB3IP.F1 (forward primer)
- refseq_RAB3IP.R1 (reverse primer)
- Single exon skipping
Frame 0
GYLAAGGRGRERRAAVAKRMKREFPNKSEAAHNTGRRAAGLWTWGGFVSQS*ETTREAPC*GVEVTL
GRFR*NLVGNSGQAPGVAPK*AAPCRQTCVRGS
*DELHGWDCMALPSQR*QLAPTAQEARAYWLQK
**CWVEVAACEELPVVMGLKKMKGLSYDEAFAMA
NDPLEGFHEVNLASPTSPDLLGVYESGTQEQTT
SPSVIYRPHPSALSSVPIQANALDVSELPTQPV
YSSPRRLNCAEISSISFHVTDPAPCSTSGVTAGL
TKLTTRKDNYNAEREFLQGATITEACDGSDDIF
GLSTDSLSRLRSPSVLEVREKGYERLKEELAKA
QRELKLKDEECERLSKVRDQLGQELEELTASLFE
EAHKMVREANIKQATAEKQLKEAQGKIDVLQAE
VAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHT
RNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSLY
NEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLTF
SKSELASAVLEAVENNTLSIEPVGLQPIRFVKA
SAVECGGPKSLLYVTFLHTFDTFSRDS*NSRMLI
RCFGRLCS*EKRCHWQSWVISKRNSDALRGTMP
ELPE*LKNG*IFLWLLDIYFQGVSLRLFSPFAN
CSKKYHDFF*TDLCCVCLFFS*THYEEFQVY**M
*FIVAKKKKNLK*INVRLNVCTFSLLALTWHLG
LAECIK**FSNYTVASFLVRGKKEV*VDSTHFP
RPPPLEWLYFYLFSILGFKKDFI*RNTSAATKFE
SYYFNYSALCN*KNPFILVIH*NIIEGSQILSQ
RCIPECLDIVYSCFICVDHYIVIGGT*M*MSLT
CVKGV*RGVD*MNGTCEVYADYRTT*SLHSKL*N
*LNWRNYNKEVCGRHVISIEKQKEKRNCFSFCL
EKAAVNIFG**PFSFQIFSTYICIFLKQKVGFF
FAF*T*TLNIFSLG*TYTS*SLFIEF*HNLIVFG
DEVVFSLFFIL*CCDEYPYLYTSEHCGVLSCGC
LEIKLCRDIYVFLNV*SALLDCHPEKLINLYSQ
QQCTRGLVF*R*HFFQSCSEVWSILPVDDFSHQA
GWEPTDKRTLVYVMVKTISTMPSSRM*N*T*KK
L*TYNFMF*K*LF*CEGINKNMYHQSFRRFSVQ
TKITFGEST*IKRETNPGDTVRFERKVIKYSEKV
C**LKKDK*KVRLKKISIPINNKSLVIYKGKNA
FQPYTLEACSLKLMQQDDDLM*KLYVEL*IKM*
LKHI*KM*LSS*SYSL*EELLKLEAGKKKTIKDN
HKRI*VMVYYKFLI*KSCISS*ALWLMPVIPAL
WEAEAEGLLELLEPRSLRRAWEK*GNSIYTHTH
THTHTHTVSMNLGG*GGRIA*AQGFKSNLGNIGR
PCL*KKN*S*TTNCEAISATFITSNSLVSRMYA
EILQTNKKGQCHRKTGKRLNQAFHTIRSACGPI
NIKRFSSLNQENVNQDDNDMFKFIRLVKMKKHKV
KFWRGF*SLGSLTYC*WGYQLVYPL*KTIH*KS
WARPSGSCLLALGGQGRRIT*AQEFKTSLSNIG
RPHLHKKIFLN*LGMVVHACGPSYLGS*GGRIA*
AQEVEAAVNHDCATALLPWVTE*DHTLKKKKKY
THGSAISLFSIYLRNACTGPPDHTYKNVLE*IK
MSIFRKV*CVHRMGDYYMAAK*MNTSYLQHNNSE
*KSNSEKTICDMILFL*KSRTTKTEQLFRH*HM
*QNF*KVIKFKIVVTSGEVEEEQIYE*VTGNVL
VPGLGGGFWGGSFVIKSKYMSWV*WCVLIVPATW
ESEIGRSLRPVQGYSVL*FHL*IATIFQPGQRR
PCPPLKKFKNKINAWTNE*ESYAWNIGGVL*IK
HYY*LSYMCLHSKTKNKR*ENC*IAFEREERKEF
RSES*AFGLSYCSLLRWGNTWWGKFGYVHNRDR
NSVFDRSSVRCPLSIKVDMLSRYWMYKSKFSKV
SPGENLGSS*PWDQMGALGTLWR*STALSPEFL*
QRSSLQRRKEELLGRARQQKRKNQHADYVQESV
STLNLIAKITNSKEEEDSWTSF*KLVWSWGESL
A*WRQLWIGSHLDLHSGLGLAPKNWEG*LGGHSS
LFMVSLSLKTIYSL*LSIHTGRTRFGF*TLGLS
P*NNLQPVTSSLTPIATTRILCVFVLCIQSKTG
LLLFIGFCFQWFLLLHFSLDKMFFL*DTA*KSPM
QYEFVFVFNFCA*QICHG*TLSCLSKILGLILG
SFICHCHSHSSYQQIPSAVSETS*ICLPPSMST
ATTLPKLLSSFT*TPALMSAVLASTPALLQSLTA
AAGIFIKRKSDNVTSLLKAL*VASHCT*KKKKK
KKLARCDGSCL*SQHFGRPRRADPLRLVVRDLL
GQHGETLSLLKTQN*SGVMAHACNPSYLGG*VRR
NARTQEAEVVVS*HHAIALQPGQQE*NSV*KKK
KKTQTQ*KIKFS*W*LLTEK*Q*KL*KTP*KFA
KLKKKM*KRTKLDKILKELKPFLKAASQGSTSSH
TVYFWRNV*GHED*ILELQVSGTVSRDTGPPSP
HPQI*PQQLSFYLYLLELSRKCQYQSKPKSQLD
*ITIQENDSLPKLCKMGISRELENVRRKDHNQEN
THHICYSLRGRNFHLNPISSSWIVLSVECSGF*
LIEIF*SSQQLPSQFSSLSADLGTRVASCGLHC
VFTQCAICPSQCFGLFFCLSILFLNNCQHLKMRK
SKICISSCSFLKCAVSTTLSPQS*MTTLGWS*V
TPPVGWLHPCSGYALHGLLYGPPSWIVSLTPRL
RDPLYSLICWALEVFQFGTPILTLASQAIK*NLI
SMMLPVTSLCC*EHEVCG*IGGRDPESLLGSGL
*CDDSFPVVSRRLGWELLLESRVSQRLHVLGIL
IHILSKGI*ILKKNHLTSSLLPTSSQ*PLLCFTS
RASGFTTAYLDFAVAS*TA*TLDIAPANTFCHR
DLSELNGIVSCPTPKQIETVNRYT*NEYAWNQI
TFRIYHYR**IQQDSRGWEG*WGLGGGRIKGLGN
GCKNL*KEYDLLFGSTIG*IQLIIYCIFHNKGV
DLECSQHK**MFEVMDTPITLI*SLYVVCLYQN
IICTP*ICTTIMYP*KLEINYHHLSSAYFPISSR
TILGTQSLYLCCLPSHCSCFKKYTYCLIYPVPL
*DDCS*Q*CVVSNS**LEGSC*MFPT*RNDKCL
R*WIC*LP*SDHYTLYVWKYHCVPHEYGQLLFVN
*KNKKKTHPLF
Frame 1
VTWRRAGAAGSGGPRSRRG*RESSRTSRKQLTTPDAARQGCGPGVVSCPSLRKLRARHRAEA*RSP
SGGFGETWWEIPGRRPESRPSRQLRAARLVFGGV
ETNCTGGIAWLCPPSVDNSPRPPRKRELTGSRS
DDAGWKSQHVKSCRLLWD*KR*KGYLMMRLLLW
LMIPWKASMK*TLLHLLLRTFLVCMNQELKSRLP
HQVSSTGHTLQLYPLYLSRQMH*MFLNFLHNPC
IHPPDV*IVRKYLVSAFMLQTQPLALPLESQLD
*LN*LQERTTIMQRESFYRVLL*QRLAMAVMIFL
G*VLIVCLVYEAHLFWKLEKRAMND*KKNSQKL
RGN*S*KMKNVRGFQKCEINLDRNWKNSQLVYL
RKLIKW*EKQISSRQQQKNS*KKHKEKLMYFKLK
*LH*RHLYCPVLQHHLRRSLCQVERHLLKRGIQ
EIKAQAVL*VAVIRTSV*YSQL*KTAKRLTYPC
IMNSDCGRMSPQWTGRVLS*TKSTRKISFHV*HS
QKVSWLQLFWRLWKTIL*ALNQWDYNLSGL*KL
LQLNAEDQNHFCM*LFYIHSIHSAGTRETAGC*
SDVLGGYAVEKRDVIGKAGLFQRGTLMLCVGPCL
NSPNN*KMAEYFYGYLIFISKE*A*DFFPLLQI
ALRSTMISFKLIYAVFAYSLVEHTMKNSRCTSE
CNL*LPKKKKT*NK*MLD*MCVHFLF*L*HGI*G
*QNVLNSNFQTTQ*LPSL*EARKKSEWIVLTFQ
GPHL*NGFIFICFLYWVSKKILFEEILLLLQSL
KVTILIILLSVTERIPLFWLFIKI**KAVRFYPR
DVFLSVLI*CIHVLYVLTTILSLEGHRCK*V*R
VSKGFKGVWIE*MVRAKYMLIIEPLDLCIPNCK
TDSTGEIITKRFVVDM**V*KSKKKRETALVSV*
RKLLLIFLDSSLSAFRYFLLTYAYF*NKK*AFF
LLFKPKH*IYFPLGKPTHPNPCL*NFNII*LCL
EMRWFSVYFSYYNAVTSILICTLLNIVEFFHVDA
WR*NCVEIYMYF*MFDLHC*IAIQKS*SICIHS
SSVQEGWFSEDNIFFSPVQRFGQSYL*MTSATR
LDGSPQTKGHWCMLW*KPSVPCLAQECEIEPEKN
FEPTILCSENSYSNVRALIRICTIKASEDFPYK
LKSLLEKVPK*KEKQIQEILYGLKER*SNTQKK
FVDDLKRINKK*D*RKSVYPLIINL**SIRGRML
FNLIH*KHAL*N*CNRMTT*CRNYMWNYRLKCD
*NIFRKCDYLPDPTPFRKNFLNWKQEKKKP*KI
TIKEYKLWYIINS*FRNRASVVRHCGSCL*SQHF
GRQRQKDYLSCLSPGV*DGPGKNRETPFTHTHT
HTHTHTLCP*TWEDEVGGLLEPRGSSPTWAT*G
DLVSKKKTKAKLQTVRQYLQHL*LVIA*YQECMQ
KFYKPTKKDSVTEKQAKD*TRPSTQLEVHVGQ*
TLRGFHLSIRKT*IKMTMTCSNSFDW*K*RNTK
SSFGEGFSH*DHSHIADGGINWYIHCEKPFTRKV
GPGPVAHASWLWEAKVGGSLEPKSSRPA*AT*G
DHICTKRFF*ISWAWWCMPVVPATWEAEVEGLL
KPRRLRLQ*IMIVPLHSYLG*QSKIIP*KKKKSI
PMGQQFHFSVYT*EMLAQVPQITHIRMFWNKLK
CLFLGRCNVFTEWVIITWQQNE*IPATCSTITQ
NEKAILRKLYVT*YFSYKSQEQLKLNSCLGIDIC
DKTFKK**SSR*WLPLER*RRSKSMSKSLVMF*
SLG*VVGFGVVHLSLKVST*AGCSGACL*SQLL
GSLR*EDP*GQFKAIVCYDFTCE*LLYSNLGNVD
LAPL*KNSKTK*MHGQMNKRVMHGTSVVYYESS
IITSSVICAFIPKQKIKGKKIVELHLRERKGKN
SGLNLRLLA*AIAVY*DGEIHGGESLGMCITETE
IQCLTDQV*GAH*ASKWIC*AGIGCTNLNSVRS
VQEKIWGVVSHGIRWAL*GHFGDEVQH*ALSSC
DREAACKDERRSC*EEQGNRKGRTSMLIMFRRVF
LR*I*LPRLPILKKRRTLGQVFRSWFGAGVRAW
PNGDSSGLGVT*TYILV*VWLPKTGKVS*VATP
LSSWSLSA*RQFTVFD*ASTLEEQDLVSEHWVLV
LKITCNLLRLHLLPSPPQESCVFLFCASSLKRV
CFYS*AFVFSGFCCCIFP*IKCFFYKTLLKRVQ
CSMNLYLCLTFVLNRSAMAELSVA*AKFWGLF*V
PLFVIVTPIPVISKFHQLSPRHLKSVYLPPCPL
LPLCPSYYHLSPELLH*CLLSLHPLLPSYNH*R
QPQGSL*NENQIMSLPCLKPFEWLPIALRKKKKK
KNWPGAMAHACNPSTLGGRGGRIP*GW*FETCL
ANMEKPCLY*KHKISQV*WRMPVIPATWEAESG
ETLEPRRQRLW*VDITPLHSSLGNKSETPSEKKK
KKPKLNRKSSFHSGSC*QRNNNESFKKLHENLQ
NLKKKCRRGLNLIKY*KN*NPS*RQLLKGAQVH
TQFTFGGTSEVMRTRF*SYRSQGQSRGIQGPHHH
IPRFNRSSSAFICICWSSLGNVNTKANPNHN*I
RLLFKRMILYRNSAKWGYQESWKM*DVKTIIRK
IRIIFVIH*EGGIST*ILFPAAGLCSQWSALDSD
**RFSSPPSNFLLNSLHFPQISAPGLHLVGSIV
FSHNVLFVLHSVLVYFSVCPSCF*TIASI*K*G
NLKSAFQAALF*NVPFRQH*AHSLE*QHLGGAE*
LHLSGGYTLAQGMHSMVCSMAHHPGLSP*HQG*
GTHFTHLSAGPWKYFSSEPQF*P*LLRPLNEIS
FL*CFLSHHCAAENMKSVGELVDGIQNHYLAVDY
SVMTHFRWSPGDLAGSFSWSLGLARGYMF*AS*
FIFYLKAYKSLKKII*LHPCSLHPASNHCFVLH
RVLQALLQPTWILQ*LLKLLKLWILPQPTHSATE
ISLS*MGLYHAPHPSR*KLSIDTLRMNMHGIKL
HSESTTIGSEYNRIAEAGKGNGGWGVGG*RGWV
MGVKIYRRNMICCLVAQ*GKYS**FIVYFTIKEW
IWNVLNTNDKCLR*WIPQLP*FDHYTLYVCIKI
SYVPHKYVQLLCIHKNWK*TTTIFLQPIFLSPL
APY*AHNLCTCAVFQAIAHVLRNILIV*YILYHC
RMTVVNNNV*FQIANSWKEVVECFQHKEMISV*
DDGYANYPDLITTHYMYGNIIVYPMNMGNYYLL
IKKIKKRPTHCL
Frame 2
LPGGGRARPGAEGRGREEDEERVPEQVGSSSQHRTPRGRAVDLGWFRVPVLGNYARGTVLRRRGHP
REVSVKPGGKFRAGARSRAQVGSSVPPDLCSGE
LRRTARVGLHGSALPALTTRPDRPGSASLLAPEV
MMLGGSRSM*RVAGCYGIKKDERVIL**GFCYG
**SLGRLP*SKPCFTYFSGPSWCV*IRNSRADY
LTKCHLPATPFSFILCTYPGKCIRCF*TSYTTRV
FIPQTFKLCGNI*YQLSCYRPSPLLYLWSHSWI
N*INYKKGQL*CRERVFTGCYYNRGLRWQ**YF
WVEY**SVSFTKPICFGS*RKGL*TIKRRTRKSS
EGTEVKR*RM*EAFKSARSTWTGIGRTHS*SI*
GSS*NGERSKYQAGNSRKTAKRSTRKN*CTSS*
SSCIEDTCIVQFSNITYAGAFARWKDTF*KGAYK
K*KHKQCYEWQSSGPQCDTANCKRLQRG*LILV
**IPIVEG*AHNGQDVSFLRQNLPGRYLSMFNI
LKK*VGFSCSGGCGKQYSKH*TSGITTYPVCESF
CS*MRRTKITSVCNFFTYIRYIQQGLVKQQDVD
QMFWEVMQLRKEMSLAKLGYFKEEL*CSAWDHA
*TPRITEKWLNIFMVT*YLFPRSEPKTFFPFCKL
L*EVP*FLLN*SMLCLLIL*LNTL*RIPGVLVN
VIYSCQKKKKPEINKC*IECVYIFSSSSDMAFR
VSRMY*IVIFKLHSSFLPCERQERSLSG*YSLSK
APTSRMALFLSVFYIGFQKRFYLKKYFCCYKV*
KLLF*LFCSL*LKESLYFGYSLKYNRRQSDFIP
EMYS*VS*YSVFMFYMC*PLYCHWRDIDVNEFDV
CQRGLKGCGLNEWYVRSIC*L*NHLISAFQIVK
LTQLEKL*QRGLW*TCNKYRKAKRKEKLL*FLF
RESCC*YFWIVAFQLSDIFYLHMHIFETKSRLFF
CFLNLNIKYIFPWVNLHILIPVYRILT*FNCVW
R*GGFQFIFHIIML*RVSLSVHF*TLWSSFMWM
PGDKIVSRYICIFKCLICIARLPSRKVNQFVFTA
AVYKRAGFLKITFFSVLFRGLVNLTCR*LQPPG
WMGAHRQKDIGVCYGENHQYHA*LKNVKLNLKK
TLNLQFYVLKIVILM*GH**EYVPSKLQKIFRTN
*NHFWRKYLNKKRNKSRRYCTV*KKGNQILRKS
LLMT*KG*IKSKTKENQYTH***IFSNL*GEEC
FSTLYTRSMLFKINATG*RLDVETICGIID*NVI
ETYLENVIIFLILLPLGRTS*TGSRKKKNHKR*
P*KNISYGIL*ILNLEIVHQ*LGIVAHACNPST
LGGRGRRIT*AA*AQEFETGLGKIGKLHLHTHTH
THTHTHCVHELGRMRWEDCLSPGVQVQLGQHRE
TLSLKKKLKLNYKL*GNICNIYN***LSIKNVC
RNSTNQQKRTVSQKNRQKTEPGLPHN*KCMWANK
H*EVFISQSGKRKSR*Q*HVQIHSIGENEETQS
QVLERVLVIRITHILLMGVSIGISTVKNHSLEK
LGQAQWLMPLGFGRPR*EDHLSPRVQDQLEQHRE
TTSAQKDFFELAGHGGACLWSQLLGKLRWKDCL
SPGG*GCSES*LCHCTLTLGDRVRSYLKKKKKV
YPWVSNFTFQYILEKCLHRSPRSHI*ECSGIN*N
VYF*EGVMCSQNG*LLHGSKMNEYQLLAAQ*LR
MKKQF*ENYM*HDTFLIKVKNN*N*TAV*ALTY
VTKLLKSNKVQDSGYLWRGRGGANL*VSHW*CFS
PWVRWWVLGWFICH*K*VHELGVVVRAYSPSYL
GV*DRKILEASSRL*CAMISPVNSYYIPTWAT*
TLPPFKKIQKQNKCMDK*IRELCMEHRWCIMNQA
LLLAQLYVPSFQNKK*KVRKLLNCI*ERGKERI
QV*ILGFWLELLQFIEMGKYMVGKVWVCA*QRQ
KFSV*QIKCEVPTEHQSGYVKQVLDVQI*IQ*GQ
SRRKFGE*LAMGSDGRFRDTLEMKYSTEP*VPV
TEKQPAKTKGGAVRKSKATEKEEPAC*LCSGEC
FYAEFNCQDYQF*RRGGLLDKFLEVGLELG*EPG
LMETALDWESLRPTFWSRFGSQKLGRLVRWPLL
SLHGLSQLEDNLQSLTKHPHWKNKIWFLNIGS*
SLK*LATCYVFTYSHRHHKNPVCFCFVHPV*NGS
AFIHRLLFSVVFVVAFFPR*NVFSIRHCLKESN
AV*ICICV*LLCLTDLPWLNSQLLKQNSGAYSR
FLYLSLSLPFQLSANSISCLRDILNLSTSLHVHC
YHSAQAIIIFHLNSCTNVCCPCIHSCPPTITDG
SRRDLYKTKIR*CHFPA*SPLSGFPLHLEKKKK
KKTGQVRWLMPVIPALWEAEAGGSPEVGSSRPAW
PTWRNPVSTKNTKLVRCDGACL*SQLLGRLSQE
KRSNPGGRGCGELTSRHCTPAWATRVKLRLKKK
KKNPNSIENQVFIVVVVNREITMKALKNSMKICK
T*KKNVEED*T**NIKRIETLPKGSFSREHKFT
HSLLLEERLRS*GLDSRATGLRDSLEGYRAPIT
TSPDLTAAAQLLSVSVGAL*EMSIPKQTQITTRL
DYYSRE*FSTETLQNGDIKRVGKCKT*RP*SGK
YASYLLFTEREEFPLKSYFQQLDCALSGVLWIL
INRDFLVLPATSFSILFTFRRSRHQGCILWAPLC
FHTMCYLSFTVFWFIFLFVHLVFEQLPAFKNEE
I*NLHFKLLFFKMCRFDNTEPTVLNDNTWVELS
DSTCRVATPLLRVCTPWFALWPTILDCLPDTKAK
GPTLLTYLLGLGSISVRNPNSNLSFSGH*MKSH
FYDASCHITVLLRT*SLWVNWWTGSRIITWQWI
IV**LISGGLQETWLGASLGV*G*PEATCFRHLN
SYFI*RHINP*KKSFDFILAPYIQPVTIALFYI
ACFRLYYSLPGFCSSFLNCLNFGYCPSQHILPQ
RSL*VKWDCIMPHTQADRNCQ*IHLE*ICMESNY
IQNLPL*VVNTTG*QRLGRVMGVGGWEDKGVG*
WV*KSIEGI*SVVW*HNRVNTVNNLLYISQ*RS
GFGMFSTQMINV*GDGYPNYPDLIIIRCMFVSKY
HMYPINMYNYYVSIKIGNKLPPSFFSLFSYLLS
HHTRHTISVPVLSSKPLLMF*EIYLLFNISCTT
VG*L*LTIMCSFK*LIAGRKLLNVSNIKK**VFE
MMDMLITLI*SLHIICMEISLCTP*IWAIIIC*
LKK*KKDPPTV*
Sequence NM_175624
GCTTCCGGCGCAGGCGCAGTCCCGCGTTCCCTCGGCGGCTGCCGGCGTAGTGAGCCCGCCGCCGTGGAGTGTAGCGGAAAGGGCTCGCCGTCCTCCTCCGTTTCTCGCTGCTTCGGGACGCGCTCTCTGCGGCTCTGTGAGCGCCCCTGAGCGCCGGCAGCGGCCGCGGTGGGTTCTTCAGGTTATCTTATGATGAGGCT
TTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTGTATGAATCAGGAACTCAAG
AGCAGACTACCTCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTTCCTAC
ACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTC
ACAGCTGGATTAACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTG
ATGATATTTTTGGGTTGAGTACTGATAGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACT
CGCAAAAGCTCAGAGGGAACTGAAGTTAAAAGATGAAGAATGTGAGAGGCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCT
AGTCTATTTGAGGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAACAGCTAAAAGAAGCACAAGGAAAAATTGATGTAC
TTCAAGCTGAAGTAGCTGCATTGAAGACACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAGACACCTTTTAAAAA
GGGGCATACAAGAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGTCATCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGAC
TTATCCTTGTATAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTCTTAGACAAAATCTACCAGGAAGATATCTTTCCAT
GTTTAACATTCTCAAAAAGTGAGTTGGCTTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTACAACCTATCCGGTT
TGTGAAAGCTTCTGCAGTTGAATGCGGAGGACCAAAATCACTTCTGTATGTAACTTTTTTACATACATTCGATACATTCAGCAGGGACTCGTGAAACAGC
AGGATGTTGATCAGATGTTTTGGGAGGTTATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTCTGATGCTCTGCGTG
GGACCATGCCTGAACTCCCCGAATAACTGAAAAATGGCTGAATATTTTTATGGTTACTTGATATTTATTTCCAAGGAGTGAGCCTAAGACTTTTTTCCCC
TTTTGCAAATTGCTCTAAGAAGTACCATGATTTCTTTTAAACTGATCTATGCTGTGTTTGCTTATTCTTTAGTTGAACACACTATGAAGAATTCCAGGTG
TACTAGTGAATGTAATTTATAGTTGCCAAAAAAAAAAAAAACCTGAAATAAATAAATGTTAGATTGAATGTGTGTACATTTTCTCTTCTAGCTCTGACAT
GGCATTTAGGGTTAGCAGAATGTATTAAATAGTAATTTTCAAACTACACAGTAGCTTCCTTCCTTGTGAGAGGCAAGAAAGAAGTCTGAGTGGATAGTAC
TCACTTTCCAAGGCCCCCACCTCTAGAATGGCTTTATTTTTATCTGTTTTCTATATTGGGTTTCAAAAAAGATTTTATTTGAAGAAATACTTCTGCTGCT
ACAAAGTTTGAAAGTTACTATTTTAATTATTCTGCTCTCTGTAACTGAAAGAATCCCTTTATTTTGGTTATTCATTAAAATATAATAGAAGGCAGTCAGA
TTTTATCCCAGAGATGTATTCCTGAGTGTCTTGATATAGTGTATTCATGTTTTATATGTGTTGACCACTATATTGTCATTGGAGGGACATAGATGTAAAT
GAGTTTGACGTGTGTCAAAGGGGTTTAAAGGGGTGTGGATTGAATGAATGGTACGTGCGAAGTATATGCTGATTATAGAACCACTTGATCTCTGCATTCC
AAATTGTAAAACTGACTCAACTGGAGAAATTATAACAAAGAGGTTTGTGGTAGACATGTAATAAGTATAGAAAAGCAAAAAGAAAAGAGAAACTGCTTTA
GTTTCTGTTTAGAGAAAGCTGCTGTTAATATTTTTGGATAGTAGCCTTTCAGCTTTCAGATATTTTCTACTTACATATGCATATTTTTGAAACAAAAAGT
AGGCTTTTTTTTTGCTTTTTAAACCTAAACATTAAATATATTTTCCCTTGGGTAAACCTACACATCCTAATCCCTGTTTATAGAATTTTAACATAATTTA
ATTGTGTTTGGAGATGAGGTGGTTTTCAGTTTATTTTTCATATTATAATGCTGTGACGAGTATCCTTATCTGTACACTTCTGAACATTGTGGAGTTCTTT
CATGTGGATGCCTGGAGATAAAATTGTGTCGAGATATATATGTATTTTTAAATGTTTGATCTGCATTGCTAGATTGCCATCCAGAAAAGTTAATCAATTT
GTATTCACAGCAGCAGTGTACAAGAGGGCTGGTTTTCTGAAGATAACATTTTTTTCAGTCCTGTTCAGAGGTTTGGTCAATCTTACCTGTAGATGACTTC
AGCCACCAGGCTGGATGGGAGCCCACAGACAAAAGGACATTGGTGTATGTTATGGTGAAAACCATCAGTACCATGCCTAGCTCAAGAATGTGAAATTGAA
CCTGAAAAAAACTTTGAACCTACAATTTTATGTTCTGAAAATAGTTATTCTAATGTGAGGGCATTAATAAGAATATGTACCATCAAAGCTTCAGAAGATT
TTCCGTACAAACTAAAATCACTTTTGGAGAAAGTACCTAAATAAAAAGAGAAACAAATCCAGGAGATACTGTACGGTTTGAAAGAAAGGTAATCAAATAC
TCAGAAAAAGTTTGTTGATGACTTAAAAAGGATAAATAAAAAGTAAGACTAAAGAAAATCAGTATACCCATTAATAATAAATCTTTAGTAATCTATAAGG
GGAAGAATGCTTTTCAACCTTATACACTAGAAGCATGCTCTTTAAAATTAATGCAACAGGATGACGACTTGATGTAGAAACTATATGTGGAATTATAGAT
TAAAATGTGATTGAAACATATTTAGAAAATGTGATTATCTTCCTGATCCTACTCCCTTTAGGAAGAACTTCTTAAACTGGAAGCAGGAAAAAAAAAAACC
ATAAAAGATAACCATAAAAGAATATAAGTTATGGTATATTATAAATTCTTAATTTAGAAATCGTGCATCAGTAGTTAGGCATTGTGGCTCATGCCTGTAA
TCCCAGCACTTTGGGAGGCAGAGGCAGAAGGATTACTTGAGCTGCTTGAGCCCAGGAGTTTGAGACGGGCCTGGGAAAAATAGGGAAACTCCATTTACAC
ACACACACACACACACACACACACACACACTGTGTCCATGAACTTGGGAGGATGAGGTGGGAGGATTGCTTGAGCCCAGGGGTTCAAGTCCAACTTGGGC
AACATAGGGAGACCTTGTCTCTAAAAAAAAAACTAAAGCTAAACTACAAACTGTGAGGCAATATCTGCAACATTTATAACTAGTAATAGCTTAGTATCAA
GAATGTATGCAGAAATTCTACAAACCAACAAAAAAGGACAGTGTCACAGAAAAACAGGCAAAAGACTGAACCAGGCCTTCCACACAATTAGAAGTGCATG
TGGGCCAATAAACATTAAGAGGTTTTCATCTCTCAATCAGGAAAACGTAAATCAAGATGACAATGACATGTTCAAATTCATTCGATTGGTGAAAATGAAG
AAACACAAAGTCAAGTTTTGGAGAGGGTTTTAGTCATTAGGATCACTCACATATTGCTGATGGGGGTATCAATTGGTATATCCACTGTGAAAAACCATTC
ACTAGAAAAGTTGGGCCAGGCCCAGTGGCTCATGCCTCTTGGCTTTGGGAGGCCAAGGTAGGAGGATCACTTGAGCCCAAGAGTTCAAGACCAGCTTGAG
CAACATAGGGAGACCACATCTGCACAAAAAGATTTTTTTGAATTAGCTGGGCATGGTGGTGCATGCCTGTGGTCCCAGCTACTTGGGAAGCTGAGGTGGA
AGGATTGCTTAAGCCCAGGAGGTTGAGGCTGCAGTGAATCATGATTGTGCCACTGCACTCTTACCTTGGGTGACAGAGTAAGATCATACCTTAAAAAAAA
AAAAAAAGTATACCCATGGGTCAGCAATTTCACTTTTCAGTATATACTTGAGAAATGCTTGCACAGGTCCCCCAGATCACACATATAAGAATGTTCTGGA
ATAAATTAAAATGTCTATTTTTAGGAAGGTGTAATGTGTTCACAGAATGGGTGATTATTACATGGCAGCAAAATGAATGAATACCAGCTACTTGCAGCAC
AATAACTCAGAATGAAAAAGCAATTCTGAGAAAACTATATGTGACATGATACTTTTCTTATAAAAGTCAAGAACAACTAAAACTGAACAGCTGTTTAGGC
ATTGACATATGTGACAAAACTTTTAAAAAGTAATAAAGTTCAAGATAGTGGTTACCTCTGGAGAGGTAGAGGAGGAGCAAATCTATGAGTAAGTCACTGG
TAATGTTTTAGTCCCTGGGTTAGGTGGTGGGTTTTGGGGTGGTTCATTTGTCATTAAAAGTAAGTACATGAGCTGGGTGTAGTGGTGCGTGCTTATAGTC
CCAGCTACTTGGGAGTCTGAGATAGGAAGATCCTTGAGGCCAGTTCAAGGCTATAGTGTGCTATGATTTCACCTGTGAATAGCTACTATATTCCAACCTG
GGCAACGTAGACCTTGCCCCCCTTTAAAAAAATTCAAAAACAAAATAAATGCATGGACAAATGAATAAGAGAGTTATGCATGGAACATCGGTGGTGTATT
ATGAATCAAGCATTATTACTAGCTCAGTTATATGTGCCTTCATTCCAAAACAAAAAATAAAAGGTAAGAAAATTGTTGAATTGCATTTGAGAGAGAGGAA
AGGAAAGAATTCAGGTCTGAATCTTAGGCTTTTGGCTTGAGCTATTGCAGTTTATTGAGATGGGGAAATACATGGTGGGGAAAGTTTGGGTATGTGCATA
ACAGAGACAGAAATTCAGTGTTTGACAGATCAAGTGTGAGGTGCCCACTGAGCATCAAAGTGGATATGTTAAGCAGGTATTGGATGTACAAATCTAAATT
CAGTAAGGTCAGTCCAGGAGAAAATTTGGGGAGTAGTTAGCCATGGGATCAGATGGGCGCTTTAGGGACACTTTGGAGATGAAGTACAGCACTGAGCCCT
GAGTTCCTGTGACAGAGAAGCAGCCTGCAAAGACGAAAGGAGGAGCTGTTAGGAAGAGCAAGGCAACAGAAAAGGAAGAACCAGCATGCTGATTATGTTC
AGGAGAGTGTTTCTACGCTGAATTTAATTGCCAAGATTACCAATTCTAAAGAAGAGGAGGACTCTTGGACAAGTTTTTAGAAGTTGGTTTGGAGCTGGGG
TGAGAGCCTGGCCTAATGGAGACAGCTCTGGATTGGGAGTCACTTAGACCTACATTCTGGTCTAGGTTTGGCTCCCAAAAACTGGGAAGGTTAGTTAGGT
GGCCACTCCTCTCTCTTCATGGTCTCTCTCAGCTTGAAGACAATTTACAGTCTTTGACTAAGCATCCACACTGGAAGAACAAGATTTGGTTTCTGAACAT
TGGGTCTTAGTCCTTAAAATAACTTGCAACCTGTTACGTCTTCACTTACTCCCATCGCCACCACAAGAATCCTGTGTGTTTTTGTTTTGTGCATCCAGTC
TAAAACGGGTCTGCTTTTATTCATAGGCTTTTGTTTTCAGTGGTTTTTGTTGTTGCATTTTTCCCTAGATAAAATGTTTTTTCTATAAGACACTGCTTAA
AAGAGTCCAATGCAGTATGAATTTGTATTTGTGTTTAACTTTTGTGCTTAACAGATCTGCCATGGCTGAACTCTCAGTTGCTTAAGCAAAATTCTGGGGC
TTATTCTAGGTTCCTTTATTTGTCATTGTCACTCCCATTCCAGTTATCAGCAAATTCCATCAGCTGTCTCCGAGACATCTTAAATCTGTCTACCTCCCTC
CATGTCCACTGCTACCACTCTGCCCAAGCTATTATCATCTTTCACCTGAACTCCTGCACTAATGTCTGCTGTCCTTGCATCCACTCCTGCCCTCCTACAA
TCACTGACGGCAGCCGCAGGGATCTTTATAAAACGAAAATCAGATAATGTCACTTCCCTGCTTAAAGCCCTTTGAGTGGCTTCCCATTGCACTTAGAAAA
AAAAAAAAAAAAAAAAACTGGCCAGGTGCGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCCCCTGAGGTTGGTAGTTCG
AGACCTGCTTGGCCAACATGGAGAAACCCTGTCTCTACTAAAAACACAAAATTAGTCAGGTGTGATGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGC
TGAGTCAGGAGAAACGCTCGAACCCAGGAGGCAGAGGTTGTGGTGAGTTGACATCACGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCT
GAAAAAAAAAAAAAAAAACCCAAACTCAATAGAAAATCAAGTTTTCATAGTGGTAGTTGTTAACAGAGAAATAACAATGAAAGCTTTAAAAAACTCCATG
AAAATTTGCAAAACTTAAAAAAAAAATGTAGAAGAGGACTAAACTTGATAAAATATTAAAAGAATTGAAACCCTTCCTAAAGGCAGCTTCTCAAGGGAGC
ACAAGTTCACACACAGTTTACTTTTGGAGGAACGTCTGAGGTCATGAGGACTAGATTCTAGAGCTACAGGTCTCAGGGACAGTCTCGAGGGATACAGGGC
CCCCATCACCACATCCCCAGATTTAACCGCAGCAGCTCAGCTTTTATCTGTATCTGTTGGAGCTCTCTAGGAAATGTCAATACCAAAGCAAACCCAAATC
ACAACTAGATTAGATTACTATTCAAGAGAATGATTCTCTACCGAAACTCTGCAAAATGGGGATATCAAGAGAGTTGGAAAATGTAAGACGTAAAGACCAT
AATCAGGAAAATACGCATCATATTTGTTATTCACTGAGAGGGAGGAATTTCCACTTAAATCCTATTTCCAGCAGCTGGATTGTGCTCTCAGTGGAGTGCT
CTGGATTCTGATTAATAGAGATTTTCTAGTCCTCCCAGCAACTTCCTTCTCAATTCTCTTCACTTTCCGCAGATCTCGGCACCAGGGTTGCATCTTGTGG
GCTCCATTGTGTTTTCACACAATGTGCTATTTGTCCTTCACAGTGTTTTGGTTTATTTTTCTGTTTGTCCATCTTGTTTTTGAACAATTGCCAGCATTTA
AAAATGAGGAAATCTAAAATCTGCATTTCAAGCTGCTCTTTTTTAAAATGTGCCGTTTCGACAACACTGAGCCCACAGTCTTGAATGACAACACTTGGGT
GGAGCTGAGTGACTCCACCTGTCGGGTGGCTACACCCTTGCTCAGGGTATGCACTCCATGGTTTGCTCTATGGCCCACCATCCTGGATTGTCTCCCTGAC
ACCAAGGCTAAGGGACCCACTTTACTCACTTATCTGCTGGGCCTTGGAAGTATTTCAGTTCGGAACCCCAATTCTAACCTTAGCTTCTCAGGCCATTAAA
TGAAATCTCATTTCTATGATGCTTCCTGTCACATCACTGTGCTGCTGAGAACATGAAGTCTGTGGGTGAATTGGTGGACGGGATCCAGAATCATTACTTG
GCAGTGGATTATAGTGTGATGACTCATTTCCGGTGGTCTCCAGGAGACTTGGCTGGGAGCTTCTCTTGGAGTCTAGGGTTAGCCAGAGGCTACATGTTTT
AGGCATCTTAATTCATATTTTATCTAAAGGCATATAAATCCTTAAAAAAAATCATTTGACTTCATCCTTGCTCCCTACATCCAGCCAGTAACCATTGCTT
TGTTTTACATCGCGTGCTTCAGGCTTTACTACAGCCTACCTGGATTTTGCAGTAGCTTCTTAAACTGCTTAAACTTTGGATATTGCCCCAGCCAACACAT
TCTGCCACAGAGATCTCTCTGAGTTAAATGGGATTGTATCATGCCCCACACCCAAGCAGATAGAAACTGTCAATAGATACACTTAGAATGAATATGCATG
GAATCAAATTACATTCAGAATCTACCACTATAGGTAGTGAATACAACAGGATAGCAGAGGCTGGGAAGGGTAATGGGGGTTGGGGGGTGGGAGGATAAAG
GGGTTGGGTAATGGGTGTAAAAATCTATAGAAGGAATATGATCTGTTGTTTGGTAGCACAATAGGGTAAATACAGTTAATAATTTATTGTATATTTCACA
ATAAAGGAGTGGATTTGGAATGTTCTCAACACAAATGATAAATGTTTGAGGTGATGGATACCCCAATTACCCTGATTTGATCATTATACGTTGTATGTTT
GTATCAAAATATCATATGTACCCCATAAATATGTACAACTATTATGTATCCATAAAAATTGGAAATAAACTACCACCATCTTTCTTCAGCCTATTTTCCT
ATCTCCTCTCGCACCATACTAGGCACACAATCTCTGTACCTGTGCTGTCTTCCAAGCCATTGCTCATGTTTTAAGAAATATACTTATTGTTTAATATATC
CTGTACCACTGTAGGATGACTGTAGTTAACAATAATGTGTAGTTTCAAATAGCTAATAGCTGGAAGGAAGTTGTTGAATGTTTCCAACATAAAGAAATGA
TAAGTGTTTGAGATGATGGATATGCTAATTACCCTGATCTGATCACTACACATTATATGTATGGAAATATCATTGTGTACCCCATGAATATGGGCAATTA
TTATTTGTTAATTAAAAAAATAAAAAAAAGACCCACCCACTGTTTAA
- refseq_RAB3IP.F1 (forward primer)
- refseq_RAB3IP.R1 (reverse primer)
- Single exon skipping
Frame 0
ASGAGAVPRSLGGCRRSEPAAVECSGKGSPSSSVSRCFGTRSLRLCERP*APAAAAVGSSGYLMMRL
LLWLMIPWKASMK*TLLHLLLRTFLVCMNQELK
SRLPHQVSSTGHTLQLYPLYLSRQMH*MFLNFL
HNPCIHPPDV*IVRKYLVSAFMLQTQPLALPLES
QLD*LN*LQERTTIMQRESFYRVLL*QRLAMAV
MIFLG*VLIVCLVYEAHLFWKLEKRAMND*KKN
SQKLRGN*S*KMKNVRGFQKCEINLDRNWKNSQL
VYLRKLIKW*EKQISSRQQQKNS*KKHKEKLMY
FKLK*LH*RHLYCPVLQHHLRRSLCQVERHLLK
RGIQEIKAQAVL*VAVIRTSV*YSQL*KTAKRLT
YPCIMNSDCGRMSPQWTGRVLS*TKSTRKISFH
V*HSQKVSWLQLFWRLWKTIL*ALNQWDYNLSG
L*KLLQLNAEDQNHFCM*LFYIHSIHSAGTRETA
GC*SDVLGGYAVEKRDVIGKAGLFQRGTLMLCV
GPCLNSPNN*KMAEYFYGYLIFISKE*A*DFFP
LLQIALRSTMISFKLIYAVFAYSLVEHTMKNSRC
TSECNL*LPKKKKT*NK*MLD*MCVHFLF*L*H
GI*G*QNVLNSNFQTTQ*LPSL*EARKKSEWIV
LTFQGPHL*NGFIFICFLYWVSKKILFEEILLLL
QSLKVTILIILLSVTERIPLFWLFIKI**KAVR
FYPRDVFLSVLI*CIHVLYVLTTILSLEGHRCK
*V*RVSKGFKGVWIE*MVRAKYMLIIEPLDLCIP
NCKTDSTGEIITKRFVVDM**V*KSKKKRETAL
VSV*RKLLLIFLDSSLSAFRYFLLTYAYF*NKK
*AFFLLFKPKH*IYFPLGKPTHPNPCL*NFNII*
LCLEMRWFSVYFSYYNAVTSILICTLLNIVEFF
HVDAWR*NCVEIYMYF*MFDLHC*IAIQKS*SI
CIHSSSVQEGWFSEDNIFFSPVQRFGQSYL*MTS
ATRLDGSPQTKGHWCMLW*KPSVPCLAQECEIE
PEKNFEPTILCSENSYSNVRALIRICTIKASED
FPYKLKSLLEKVPK*KEKQIQEILYGLKER*SNT
QKKFVDDLKRINKK*D*RKSVYPLIINL**SIR
GRMLFNLIH*KHAL*N*CNRMTT*CRNYMWNYR
LKCD*NIFRKCDYLPDPTPFRKNFLNWKQEKKKP
*KITIKEYKLWYIINS*FRNRASVVRHCGSCL*
SQHFGRQRQKDYLSCLSPGV*DGPGKNRETPFT
HTHTHTHTHTLCP*TWEDEVGGLLEPRGSSPTWA
T*GDLVSKKKTKAKLQTVRQYLQHL*LVIA*YQ
ECMQKFYKPTKKDSVTEKQAKD*TRPSTQLEVH
VGQ*TLRGFHLSIRKT*IKMTMTCSNSFDW*K*R
NTKSSFGEGFSH*DHSHIADGGINWYIHCEKPF
TRKVGPGPVAHASWLWEAKVGGSLEPKSSRPA*
AT*GDHICTKRFF*ISWAWWCMPVVPATWEAEVE
GLLKPRRLRLQ*IMIVPLHSYLG*QSKIIP*KK
KKSIPMGQQFHFSVYT*EMLAQVPQITHIRMFW
NKLKCLFLGRCNVFTEWVIITWQQNE*IPATCST
ITQNEKAILRKLYVT*YFSYKSQEQLKLNSCLG
IDICDKTFKK**SSR*WLPLER*RRSKSMSKSL
VMF*SLG*VVGFGVVHLSLKVST*AGCSGACL*S
QLLGSLR*EDP*GQFKAIVCYDFTCE*LLYSNL
GNVDLAPL*KNSKTK*MHGQMNKRVMHGTSVVY
YESSIITSSVICAFIPKQKIKGKKIVELHLRERK
GKNSGLNLRLLA*AIAVY*DGEIHGGESLGMCI
TETEIQCLTDQV*GAH*ASKWIC*AGIGCTNLN
SVRSVQEKIWGVVSHGIRWAL*GHFGDEVQH*AL
SSCDREAACKDERRSC*EEQGNRKGRTSMLIMF
RRVFLR*I*LPRLPILKKRRTLGQVFRSWFGAG
VRAWPNGDSSGLGVT*TYILV*VWLPKTGKVS*V
ATPLSSWSLSA*RQFTVFD*ASTLEEQDLVSEH
WVLVLKITCNLLRLHLLPSPPQESCVFLFCASS
LKRVCFYS*AFVFSGFCCCIFP*IKCFFYKTLLK
RVQCSMNLYLCLTFVLNRSAMAELSVA*AKFWG
LF*VPLFVIVTPIPVISKFHQLSPRHLKSVYLP
PCPLLPLCPSYYHLSPELLH*CLLSLHPLLPSYN
H*RQPQGSL*NENQIMSLPCLKPFEWLPIALRK
KKKKKNWPGAMAHACNPSTLGGRGGRIP*GW*F
ETCLANMEKPCLY*KHKISQV*WRMPVIPATWEA
ESGETLEPRRQRLW*VDITPLHSSLGNKSETPS
EKKKKKPKLNRKSSFHSGSC*QRNNNESFKKLH
ENLQNLKKKCRRGLNLIKY*KN*NPS*RQLLKGA
QVHTQFTFGGTSEVMRTRF*SYRSQGQSRGIQG
PHHHIPRFNRSSSAFICICWSSLGNVNTKANPN
HN*IRLLFKRMILYRNSAKWGYQESWKM*DVKTI
IRKIRIIFVIH*EGGIST*ILFPAAGLCSQWSA
LDSD**RFSSPPSNFLLNSLHFPQISAPGLHLV
GSIVFSHNVLFVLHSVLVYFSVCPSCF*TIASI*
K*GNLKSAFQAALF*NVPFRQH*AHSLE*QHLG
GAE*LHLSGGYTLAQGMHSMVCSMAHHPGLSP*
HQG*GTHFTHLSAGPWKYFSSEPQF*P*LLRPLN
EISFL*CFLSHHCAAENMKSVGELVDGIQNHYL
AVDYSVMTHFRWSPGDLAGSFSWSLGLARGYMF
*AS*FIFYLKAYKSLKKII*LHPCSLHPASNHCF
VLHRVLQALLQPTWILQ*LLKLLKLWILPQPTH
SATEISLS*MGLYHAPHPSR*KLSIDTLRMNMH
GIKLHSESTTIGSEYNRIAEAGKGNGGWGVGG*R
GWVMGVKIYRRNMICCLVAQ*GKYS**FIVYFT
IKEWIWNVLNTNDKCLR*WIPQLP*FDHYTLYV
CIKISYVPHKYVQLLCIHKNWK*TTTIFLQPIFL
SPLAPY*AHNLCTCAVFQAIAHVLRNILIV*YI
LYHCRMTVVNNNV*FQIANSWKEVVECFQHKEM
ISV*DDGYANYPDLITTHYMYGNIIVYPMNMGNY
YLLIKKIKKRPTHCL
Frame 1
LPAQAQSRVPSAAAGVVSPPPWSVAERARRPPPFLAASGRALCGSVSAPERRQRPRWVLQVIL**G
FCYG**SLGRLP*SKPCFTYFSGPSWCV*IRNSR
ADYLTKCHLPATPFSFILCTYPGKCIRCF*TSY
TTRVFIPQTFKLCGNI*YQLSCYRPSPLLYLWS
HSWIN*INYKKGQL*CRERVFTGCYYNRGLRWQ*
*YFWVEY**SVSFTKPICFGS*RKGL*TIKRRT
RKSSEGTEVKR*RM*EAFKSARSTWTGIGRTHS
*SI*GSS*NGERSKYQAGNSRKTAKRSTRKN*CT
SS*SSCIEDTCIVQFSNITYAGAFARWKDTF*K
GAYKK*KHKQCYEWQSSGPQCDTANCKRLQRG*
LILV**IPIVEG*AHNGQDVSFLRQNLPGRYLSM
FNILKK*VGFSCSGGCGKQYSKH*TSGITTYPV
CESFCS*MRRTKITSVCNFFTYIRYIQQGLVKQ
QDVDQMFWEVMQLRKEMSLAKLGYFKEEL*CSAW
DHA*TPRITEKWLNIFMVT*YLFPRSEPKTFFP
FCKLL*EVP*FLLN*SMLCLLIL*LNTL*RIPG
VLVNVIYSCQKKKKPEINKC*IECVYIFSSSSDM
AFRVSRMY*IVIFKLHSSFLPCERQERSLSG*Y
SLSKAPTSRMALFLSVFYIGFQKRFYLKKYFCC
YKV*KLLF*LFCSL*LKESLYFGYSLKYNRRQSD
FIPEMYS*VS*YSVFMFYMC*PLYCHWRDIDVN
EFDVCQRGLKGCGLNEWYVRSIC*L*NHLISAF
QIVKLTQLEKL*QRGLW*TCNKYRKAKRKEKLL*
FLFRESCC*YFWIVAFQLSDIFYLHMHIFETKS
RLFFCFLNLNIKYIFPWVNLHILIPVYRILT*F
NCVWR*GGFQFIFHIIML*RVSLSVHF*TLWSSF
MWMPGDKIVSRYICIFKCLICIARLPSRKVNQF
VFTAAVYKRAGFLKITFFSVLFRGLVNLTCR*L
QPPGWMGAHRQKDIGVCYGENHQYHA*LKNVKLN
LKKTLNLQFYVLKIVILM*GH**EYVPSKLQKI
FRTN*NHFWRKYLNKKRNKSRRYCTV*KKGNQI
LRKSLLMT*KG*IKSKTKENQYTH***IFSNL*G
EECFSTLYTRSMLFKINATG*RLDVETICGIID
*NVIETYLENVIIFLILLPLGRTS*TGSRKKKN
HKR*P*KNISYGIL*ILNLEIVHQ*LGIVAHACN
PSTLGGRGRRIT*AA*AQEFETGLGKIGKLHLH
THTHTHTHTHCVHELGRMRWEDCLSPGVQVQLG
QHRETLSLKKKLKLNYKL*GNICNIYN***LSIK
NVCRNSTNQQKRTVSQKNRQKTEPGLPHN*KCM
WANKH*EVFISQSGKRKSR*Q*HVQIHSIGENE
ETQSQVLERVLVIRITHILLMGVSIGISTVKNHS
LEKLGQAQWLMPLGFGRPR*EDHLSPRVQDQLE
QHRETTSAQKDFFELAGHGGACLWSQLLGKLRW
KDCLSPGG*GCSES*LCHCTLTLGDRVRSYLKKK
KKVYPWVSNFTFQYILEKCLHRSPRSHI*ECSG
IN*NVYF*EGVMCSQNG*LLHGSKMNEYQLLAA
Q*LRMKKQF*ENYM*HDTFLIKVKNN*N*TAV*A
LTYVTKLLKSNKVQDSGYLWRGRGGANL*VSHW
*CFSPWVRWWVLGWFICH*K*VHELGVVVRAYS
PSYLGV*DRKILEASSRL*CAMISPVNSYYIPTW
AT*TLPPFKKIQKQNKCMDK*IRELCMEHRWCI
MNQALLLAQLYVPSFQNKK*KVRKLLNCI*ERG
KERIQV*ILGFWLELLQFIEMGKYMVGKVWVCA*
QRQKFSV*QIKCEVPTEHQSGYVKQVLDVQI*I
Q*GQSRRKFGE*LAMGSDGRFRDTLEMKYSTEP
*VPVTEKQPAKTKGGAVRKSKATEKEEPAC*LCS
GECFYAEFNCQDYQF*RRGGLLDKFLEVGLELG
*EPGLMETALDWESLRPTFWSRFGSQKLGRLVR
WPLLSLHGLSQLEDNLQSLTKHPHWKNKIWFLNI
GS*SLK*LATCYVFTYSHRHHKNPVCFCFVHPV
*NGSAFIHRLLFSVVFVVAFFPR*NVFSIRHCL
KESNAV*ICICV*LLCLTDLPWLNSQLLKQNSGA
YSRFLYLSLSLPFQLSANSISCLRDILNLSTSL
HVHCYHSAQAIIIFHLNSCTNVCCPCIHSCPPT
ITDGSRRDLYKTKIR*CHFPA*SPLSGFPLHLEK
KKKKKTGQVRWLMPVIPALWEAEAGGSPEVGSS
RPAWPTWRNPVSTKNTKLVRCDGACL*SQLLGR
LSQEKRSNPGGRGCGELTSRHCTPAWATRVKLRL
KKKKKNPNSIENQVFIVVVVNREITMKALKNSM
KICKT*KKNVEED*T**NIKRIETLPKGSFSRE
HKFTHSLLLEERLRS*GLDSRATGLRDSLEGYRA
PITTSPDLTAAAQLLSVSVGAL*EMSIPKQTQI
TTRLDYYSRE*FSTETLQNGDIKRVGKCKT*RP
*SGKYASYLLFTEREEFPLKSYFQQLDCALSGVL
WILINRDFLVLPATSFSILFTFRRSRHQGCILW
APLCFHTMCYLSFTVFWFIFLFVHLVFEQLPAF
KNEEI*NLHFKLLFFKMCRFDNTEPTVLNDNTWV
ELSDSTCRVATPLLRVCTPWFALWPTILDCLPD
TKAKGPTLLTYLLGLGSISVRNPNSNLSFSGH*
MKSHFYDASCHITVLLRT*SLWVNWWTGSRIITW
QWIIV**LISGGLQETWLGASLGV*G*PEATCF
RHLNSYFI*RHINP*KKSFDFILAPYIQPVTIA
LFYIACFRLYYSLPGFCSSFLNCLNFGYCPSQHI
LPQRSL*VKWDCIMPHTQADRNCQ*IHLE*ICM
ESNYIQNLPL*VVNTTG*QRLGRVMGVGGWEDK
GVG*WV*KSIEGI*SVVW*HNRVNTVNNLLYISQ
*RSGFGMFSTQMINV*GDGYPNYPDLIIIRCMF
VSKYHMYPINMYNYYVSIKIGNKLPPSFFSLFS
YLLSHHTRHTISVPVLSSKPLLMF*EIYLLFNIS
CTTVG*L*LTIMCSFK*LIAGRKLLNVSNIKK*
*VFEMMDMLITLI*SLHIICMEISLCTP*IWAI
IIC*LKK*KKDPPTV*
Frame 2
FRRRRSPAFPRRLPA**ARRRGV*RKGLAVLLRFSLLRDALSAAL*APLSAGSGRGGFFRLSYDEA
FAMANDPLEGFHEVNLASPTSPDLLGVYESGTQ
EQTTSPSVIYRPHPSALSSVPIQANALDVSELPT
QPVYSSPRRLNCAEISSISFHVTDPAPCSTSGV
TAGLTKLTTRKDNYNAEREFLQGATITEACDGS
DDIFGLSTDSLSRLRSPSVLEVREKGYERLKEEL
AKAQRELKLKDEECERLSKVRDQLGQELEELTA
SLFEEAHKMVREANIKQATAEKQLKEAQGKIDV
LQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKK
GHTRNKSTSSAMSGSHQDLSVIQPIVKDCKEAD
LSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFP
CLTFSKSELASAVLEAVENNTLSIEPVGLQPIRF
VKASAVECGGPKSLLYVTFLHTFDTFSRDS*NS
RMLIRCFGRLCS*EKRCHWQSWVISKRNSDALR
GTMPELPE*LKNG*IFLWLLDIYFQGVSLRLFSP
FANCSKKYHDFF*TDLCCVCLFFS*THYEEFQV
Y**M*FIVAKKKKNLK*INVRLNVCTFSLLALT
WHLGLAECIK**FSNYTVASFLVRGKKEV*VDST
HFPRPPPLEWLYFYLFSILGFKKDFI*RNTSAA
TKFESYYFNYSALCN*KNPFILVIH*NIIEGSQ
ILSQRCIPECLDIVYSCFICVDHYIVIGGT*M*M
SLTCVKGV*RGVD*MNGTCEVYADYRTT*SLHS
KL*N*LNWRNYNKEVCGRHVISIEKQKEKRNCF
SFCLEKAAVNIFG**PFSFQIFSTYICIFLKQKV
GFFFAF*T*TLNIFSLG*TYTS*SLFIEF*HNL
IVFGDEVVFSLFFIL*CCDEYPYLYTSEHCGVL
SCGCLEIKLCRDIYVFLNV*SALLDCHPEKLINL
YSQQQCTRGLVF*R*HFFQSCSEVWSILPVDDF
SHQAGWEPTDKRTLVYVMVKTISTMPSSRM*N*
T*KKL*TYNFMF*K*LF*CEGINKNMYHQSFRRF
SVQTKITFGEST*IKRETNPGDTVRFERKVIKY
SEKVC**LKKDK*KVRLKKISIPINNKSLVIYK
GKNAFQPYTLEACSLKLMQQDDDLM*KLYVEL*I
KM*LKHI*KM*LSS*SYSL*EELLKLEAGKKKT
IKDNHKRI*VMVYYKFLI*KSCISS*ALWLMPV
IPALWEAEAEGLLELLEPRSLRRAWEK*GNSIYT
HTHTHTHTHTVSMNLGG*GGRIA*AQGFKSNLG
NIGRPCL*KKN*S*TTNCEAISATFITSNSLVS
RMYAEILQTNKKGQCHRKTGKRLNQAFHTIRSAC
GPINIKRFSSLNQENVNQDDNDMFKFIRLVKMK
KHKVKFWRGF*SLGSLTYC*WGYQLVYPL*KTI
H*KSWARPSGSCLLALGGQGRRIT*AQEFKTSLS
NIGRPHLHKKIFLN*LGMVVHACGPSYLGS*GG
RIA*AQEVEAAVNHDCATALLPWVTE*DHTLKK
KKKYTHGSAISLFSIYLRNACTGPPDHTYKNVLE
*IKMSIFRKV*CVHRMGDYYMAAK*MNTSYLQH
NNSE*KSNSEKTICDMILFL*KSRTTKTEQLFR
H*HM*QNF*KVIKFKIVVTSGEVEEEQIYE*VTG
NVLVPGLGGGFWGGSFVIKSKYMSWV*WCVLIV
PATWESEIGRSLRPVQGYSVL*FHL*IATIFQP
GQRRPCPPLKKFKNKINAWTNE*ESYAWNIGGVL
*IKHYY*LSYMCLHSKTKNKR*ENC*IAFEREE
RKEFRSES*AFGLSYCSLLRWGNTWWGKFGYVH
NRDRNSVFDRSSVRCPLSIKVDMLSRYWMYKSKF
SKVSPGENLGSS*PWDQMGALGTLWR*STALSP
EFL*QRSSLQRRKEELLGRARQQKRKNQHADYV
QESVSTLNLIAKITNSKEEEDSWTSF*KLVWSWG
ESLA*WRQLWIGSHLDLHSGLGLAPKNWEG*LG
GHSSLFMVSLSLKTIYSL*LSIHTGRTRFGF*T
LGLSP*NNLQPVTSSLTPIATTRILCVFVLCIQS
KTGLLLFIGFCFQWFLLLHFSLDKMFFL*DTA*
KSPMQYEFVFVFNFCA*QICHG*TLSCLSKILG
LILGSFICHCHSHSSYQQIPSAVSETS*ICLPPS
MSTATTLPKLLSSFT*TPALMSAVLASTPALLQ
SLTAAAGIFIKRKSDNVTSLLKAL*VASHCT*K
KKKKKKLARCDGSCL*SQHFGRPRRADPLRLVVR
DLLGQHGETLSLLKTQN*SGVMAHACNPSYLGG
*VRRNARTQEAEVVVS*HHAIALQPGQQE*NSV
*KKKKKTQTQ*KIKFS*W*LLTEK*Q*KL*KTP*
KFAKLKKKM*KRTKLDKILKELKPFLKAASQGS
TSSHTVYFWRNV*GHED*ILELQVSGTVSRDTG
PPSPHPQI*PQQLSFYLYLLELSRKCQYQSKPKS
QLD*ITIQENDSLPKLCKMGISRELENVRRKDH
NQENTHHICYSLRGRNFHLNPISSSWIVLSVEC
SGF*LIEIF*SSQQLPSQFSSLSADLGTRVASCG
LHCVFTQCAICPSQCFGLFFCLSILFLNNCQHL
KMRKSKICISSCSFLKCAVSTTLSPQS*MTTLG
WS*VTPPVGWLHPCSGYALHGLLYGPPSWIVSLT
PRLRDPLYSLICWALEVFQFGTPILTLASQAIK
*NLISMMLPVTSLCC*EHEVCG*IGGRDPESLL
GSGL*CDDSFPVVSRRLGWELLLESRVSQRLHVL
GILIHILSKGI*ILKKNHLTSSLLPTSSQ*PLL
CFTSRASGFTTAYLDFAVAS*TA*TLDIAPANT
FCHRDLSELNGIVSCPTPKQIETVNRYT*NEYAW
NQITFRIYHYR**IQQDSRGWEG*WGLGGGRIK
GLGNGCKNL*KEYDLLFGSTIG*IQLIIYCIFH
NKGVDLECSQHK**MFEVMDTPITLI*SLYVVCL
YQNIICTP*ICTTIMYP*KLEINYHHLSSAYFP
ISSRTILGTQSLYLCCLPSHCSCFKKYTYCLIY
PVPL*DDCS*Q*CVVSNS**LEGSC*MFPT*RND
KCLR*WIC*LP*SDHYTLYVWKYHCVPHEYGQL
LFVN*KNKKKTHPLF
Sequence NM_001024647
CTAAGCAAGCCTGGGCAATGGCGGGCGTCCCTCCCCCAGCCTCGTTGCCGCCTTGCAGTTTGATCTCAGACTGCTGTGCTAGCAATCAGCGAGATTCCGTGGGCGTAGGACCCTCTGAGCCAGGTGTGGGATATAGTCTCGTGGTGCGCCGTTTCTTAAGCCGGTCTGAAAAGCGCAATATTCGGATGGGAGTGACCCGA
TTTTCCAGGAACTGAAGTTAAAAGATGAAGAATGTGAGAGGCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCTAGTCTATT
TGAGGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAACAGCTAAAAGAAGCACAAGGAAAAATTGATGTACTTCAAGCT
GAAGTAGCTGCATTGAAGACACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAGACACCTTTTAAAAAGGGGCATA
CAAGAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGTCATCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGACTTATCCTT
GTATAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTCTTAGACAAAATCTACCAGGAAGATATCTTTCCATGTTTAACA
TTCTCAAAAAGTGAGTTGGCTTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTACAACCTATCCGGTTTGTGAAAG
CTTCTGCAGTTGAATGCGGAGGACCAAAAAAATGTGCTCTCACTGGCCAGAGTAAGTCCTGTAAACACAGAATTAAATTAGGGGACTCAAGCAACTATTA
TTATATTTCTCCTTTTTGCAGATACAGGATCACTTCTGTATGTAACTTTTTTACATACATTCGATACATTCAGCAGGGACTCGTGAAACAGCAGGATGTT
GATCAGATGTTTTGGGAGGTTATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTCTGATGCTCTGCGTGGGACCATG
CCTGAACTCCCCGAATAACTGAAAAATGGCTGAATATTTTTATGGTTACTTGATATTTATTTCCAAGGAGTGAGCCTAAGACTTTTTTCCCCTTTTGCAA
ATTGCTCTAAGAAGTACCATGATTTCTTTTAAACTGATCTATGCTGTGTTTGCTTATTCTTTAGTTGAACACACTATGAAGAATTCCAGGTGTACTAGTG
AATGTAATTTATAGTTGCCAAAAAAAAAAAAAACCTGAAATAAATAAATGTTAGATTGAATGTGTGTACATTTTCTCTTCTAGCTCTGACATGGCATTTA
GGGTTAGCAGAATGTATTAAATAGTAATTTTCAAACTACACAGTAGCTTCCTTCCTTGTGAGAGGCAAGAAAGAAGTCTGAGTGGATAGTACTCACTTTC
CAAGGCCCCCACCTCTAGAATGGCTTTATTTTTATCTGTTTTCTATATTGGGTTTCAAAAAAGATTTTATTTGAAGAAATACTTCTGCTGCTACAAAGTT
TGAAAGTTACTATTTTAATTATTCTGCTCTCTGTAACTGAAAGAATCCCTTTATTTTGGTTATTCATTAAAATATAATAGAAGGCAGTCAGATTTTATCC
CAGAGATGTATTCCTGAGTGTCTTGATATAGTGTATTCATGTTTTATATGTGTTGACCACTATATTGTCATTGGAGGGACATAGATGTAAATGAGTTTGA
CGTGTGTCAAAGGGGTTTAAAGGGGTGTGGATTGAATGAATGGTACGTGCGAAGTATATGCTGATTATAGAACCACTTGATCTCTGCATTCCAAATTGTA
AAACTGACTCAACTGGAGAAATTATAACAAAGAGGTTTGTGGTAGACATGTAATAAGTATAGAAAAGCAAAAAGAAAAGAGAAACTGCTTTAGTTTCTGT
TTAGAGAAAGCTGCTGTTAATATTTTTGGATAGTAGCCTTTCAGCTTTCAGATATTTTCTACTTACATATGCATATTTTTGAAACAAAAAGTAGGCTTTT
TTTTTGCTTTTTAAACCTAAACATTAAATATATTTTCCCTTGGGTAAACCTACACATCCTAATCCCTGTTTATAGAATTTTAACATAATTTAATTGTGTT
TGGAGATGAGGTGGTTTTCAGTTTATTTTTCATATTATAATGCTGTGACGAGTATCCTTATCTGTACACTTCTGAACATTGTGGAGTTCTTTCATGTGGA
TGCCTGGAGATAAAATTGTGTCGAGATATATATGTATTTTTAAATGTTTGATCTGCATTGCTAGATTGCCATCCAGAAAAGTTAATCAATTTGTATTCAC
AGCAGCAGTGTACAAGAGGGCTGGTTTTCTGAAGATAACATTTTTTTCAGTCCTGTTCAGAGGTTTGGTCAATCTTACCTGTAGATGACTTCAGCCACCA
GGCTGGATGGGAGCCCACAGACAAAAGGACATTGGTGTATGTTATGGTGAAAACCATCAGTACCATGCCTAGCTCAAGAATGTGAAATTGAACCTGAAAA
AAACTTTGAACCTACAATTTTATGTTCTGAAAATAGTTATTCTAATGTGAGGGCATTAATAAGAATATGTACCATCAAAGCTTCAGAAGATTTTCCGTAC
AAACTAAAATCACTTTTGGAGAAAGTACCTAAATAAAAAGAGAAACAAATCCAGGAGATACTGTACGGTTTGAAAGAAAGGTAATCAAATACTCAGAAAA
AGTTTGTTGATGACTTAAAAAGGATAAATAAAAAGTAAGACTAAAGAAAATCAGTATACCCATTAATAATAAATCTTTAGTAATCTATAAGGGGAAGAAT
GCTTTTCAACCTTATACACTAGAAGCATGCTCTTTAAAATTAATGCAACAGGATGACGACTTGATGTAGAAACTATATGTGGAATTATAGATTAAAATGT
GATTGAAACATATTTAGAAAATGTGATTATCTTCCTGATCCTACTCCCTTTAGGAAGAACTTCTTAAACTGGAAGCAGGAAAAAAAAAAACCATAAAAGA
TAACCATAAAAGAATATAAGTTATGGTATATTATAAATTCTTAATTTAGAAATCGTGCATCAGTAGTTAGGCATTGTGGCTCATGCCTGTAATCCCAGCA
CTTTGGGAGGCAGAGGCAGAAGGATTACTTGAGCTGCTTGAGCCCAGGAGTTTGAGACGGGCCTGGGAAAAATAGGGAAACTCCATTTACACACACACAC
ACACACACACACACACACACACTGTGTCCATGAACTTGGGAGGATGAGGTGGGAGGATTGCTTGAGCCCAGGGGTTCAAGTCCAACTTGGGCAACATAGG
GAGACCTTGTCTCTAAAAAAAAAACTAAAGCTAAACTACAAACTGTGAGGCAATATCTGCAACATTTATAACTAGTAATAGCTTAGTATCAAGAATGTAT
GCAGAAATTCTACAAACCAACAAAAAAGGACAGTGTCACAGAAAAACAGGCAAAAGACTGAACCAGGCCTTCCACACAATTAGAAGTGCATGTGGGCCAA
TAAACATTAAGAGGTTTTCATCTCTCAATCAGGAAAACGTAAATCAAGATGACAATGACATGTTCAAATTCATTCGATTGGTGAAAATGAAGAAACACAA
AGTCAAGTTTTGGAGAGGGTTTTAGTCATTAGGATCACTCACATATTGCTGATGGGGGTATCAATTGGTATATCCACTGTGAAAAACCATTCACTAGAAA
AGTTGGGCCAGGCCCAGTGGCTCATGCCTCTTGGCTTTGGGAGGCCAAGGTAGGAGGATCACTTGAGCCCAAGAGTTCAAGACCAGCTTGAGCAACATAG
GGAGACCACATCTGCACAAAAAGATTTTTTTGAATTAGCTGGGCATGGTGGTGCATGCCTGTGGTCCCAGCTACTTGGGAAGCTGAGGTGGAAGGATTGC
TTAAGCCCAGGAGGTTGAGGCTGCAGTGAATCATGATTGTGCCACTGCACTCTTACCTTGGGTGACAGAGTAAGATCATACCTTAAAAAAAAAAAAAAAG
TATACCCATGGGTCAGCAATTTCACTTTTCAGTATATACTTGAGAAATGCTTGCACAGGTCCCCCAGATCACACATATAAGAATGTTCTGGAATAAATTA
AAATGTCTATTTTTAGGAAGGTGTAATGTGTTCACAGAATGGGTGATTATTACATGGCAGCAAAATGAATGAATACCAGCTACTTGCAGCACAATAACTC
AGAATGAAAAAGCAATTCTGAGAAAACTATATGTGACATGATACTTTTCTTATAAAAGTCAAGAACAACTAAAACTGAACAGCTGTTTAGGCATTGACAT
ATGTGACAAAACTTTTAAAAAGTAATAAAGTTCAAGATAGTGGTTACCTCTGGAGAGGTAGAGGAGGAGCAAATCTATGAGTAAGTCACTGGTAATGTTT
TAGTCCCTGGGTTAGGTGGTGGGTTTTGGGGTGGTTCATTTGTCATTAAAAGTAAGTACATGAGCTGGGTGTAGTGGTGCGTGCTTATAGTCCCAGCTAC
TTGGGAGTCTGAGATAGGAAGATCCTTGAGGCCAGTTCAAGGCTATAGTGTGCTATGATTTCACCTGTGAATAGCTACTATATTCCAACCTGGGCAACGT
AGACCTTGCCCCCCTTTAAAAAAATTCAAAAACAAAATAAATGCATGGACAAATGAATAAGAGAGTTATGCATGGAACATCGGTGGTGTATTATGAATCA
AGCATTATTACTAGCTCAGTTATATGTGCCTTCATTCCAAAACAAAAAATAAAAGGTAAGAAAATTGTTGAATTGCATTTGAGAGAGAGGAAAGGAAAGA
ATTCAGGTCTGAATCTTAGGCTTTTGGCTTGAGCTATTGCAGTTTATTGAGATGGGGAAATACATGGTGGGGAAAGTTTGGGTATGTGCATAACAGAGAC
AGAAATTCAGTGTTTGACAGATCAAGTGTGAGGTGCCCACTGAGCATCAAAGTGGATATGTTAAGCAGGTATTGGATGTACAAATCTAAATTCAGTAAGG
TCAGTCCAGGAGAAAATTTGGGGAGTAGTTAGCCATGGGATCAGATGGGCGCTTTAGGGACACTTTGGAGATGAAGTACAGCACTGAGCCCTGAGTTCCT
GTGACAGAGAAGCAGCCTGCAAAGACGAAAGGAGGAGCTGTTAGGAAGAGCAAGGCAACAGAAAAGGAAGAACCAGCATGCTGATTATGTTCAGGAGAGT
GTTTCTACGCTGAATTTAATTGCCAAGATTACCAATTCTAAAGAAGAGGAGGACTCTTGGACAAGTTTTTAGAAGTTGGTTTGGAGCTGGGGTGAGAGCC
TGGCCTAATGGAGACAGCTCTGGATTGGGAGTCACTTAGACCTACATTCTGGTCTAGGTTTGGCTCCCAAAAACTGGGAAGGTTAGTTAGGTGGCCACTC
CTCTCTCTTCATGGTCTCTCTCAGCTTGAAGACAATTTACAGTCTTTGACTAAGCATCCACACTGGAAGAACAAGATTTGGTTTCTGAACATTGGGTCTT
AGTCCTTAAAATAACTTGCAACCTGTTACGTCTTCACTTACTCCCATCGCCACCACAAGAATCCTGTGTGTTTTTGTTTTGTGCATCCAGTCTAAAACGG
GTCTGCTTTTATTCATAGGCTTTTGTTTTCAGTGGTTTTTGTTGTTGCATTTTTCCCTAGATAAAATGTTTTTTCTATAAGACACTGCTTAAAAGAGTCC
AATGCAGTATGAATTTGTATTTGTGTTTAACTTTTGTGCTTAACAGATCTGCCATGGCTGAACTCTCAGTTGCTTAAGCAAAATTCTGGGGCTTATTCTA
GGTTCCTTTATTTGTCATTGTCACTCCCATTCCAGTTATCAGCAAATTCCATCAGCTGTCTCCGAGACATCTTAAATCTGTCTACCTCCCTCCATGTCCA
CTGCTACCACTCTGCCCAAGCTATTATCATCTTTCACCTGAACTCCTGCACTAATGTCTGCTGTCCTTGCATCCACTCCTGCCCTCCTACAATCACTGAC
GGCAGCCGCAGGGATCTTTATAAAACGAAAATCAGATAATGTCACTTCCCTGCTTAAAGCCCTTTGAGTGGCTTCCCATTGCACTTAGAAAAAAAAAAAA
AAAAAAAAACTGGCCAGGTGCGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCCCCTGAGGTTGGTAGTTCGAGACCTGC
TTGGCCAACATGGAGAAACCCTGTCTCTACTAAAAACACAAAATTAGTCAGGTGTGATGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGTCAG
GAGAAACGCTCGAACCCAGGAGGCAGAGGTTGTGGTGAGTTGACATCACGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTGAAAAAAA
AAAAAAAAAACCCAAACTCAATAGAAAATCAAGTTTTCATAGTGGTAGTTGTTAACAGAGAAATAACAATGAAAGCTTTAAAAAACTCCATGAAAATTTG
CAAAACTTAAAAAAAAAATGTAGAAGAGGACTAAACTTGATAAAATATTAAAAGAATTGAAACCCTTCCTAAAGGCAGCTTCTCAAGGGAGCACAAGTTC
ACACACAGTTTACTTTTGGAGGAACGTCTGAGGTCATGAGGACTAGATTCTAGAGCTACAGGTCTCAGGGACAGTCTCGAGGGATACAGGGCCCCCATCA
CCACATCCCCAGATTTAACCGCAGCAGCTCAGCTTTTATCTGTATCTGTTGGAGCTCTCTAGGAAATGTCAATACCAAAGCAAACCCAAATCACAACTAG
ATTAGATTACTATTCAAGAGAATGATTCTCTACCGAAACTCTGCAAAATGGGGATATCAAGAGAGTTGGAAAATGTAAGACGTAAAGACCATAATCAGGA
AAATACGCATCATATTTGTTATTCACTGAGAGGGAGGAATTTCCACTTAAATCCTATTTCCAGCAGCTGGATTGTGCTCTCAGTGGAGTGCTCTGGATTC
TGATTAATAGAGATTTTCTAGTCCTCCCAGCAACTTCCTTCTCAATTCTCTTCACTTTCCGCAGATCTCGGCACCAGGGTTGCATCTTGTGGGCTCCATT
GTGTTTTCACACAATGTGCTATTTGTCCTTCACAGTGTTTTGGTTTATTTTTCTGTTTGTCCATCTTGTTTTTGAACAATTGCCAGCATTTAAAAATGAG
GAAATCTAAAATCTGCATTTCAAGCTGCTCTTTTTTAAAATGTGCCGTTTCGACAACACTGAGCCCACAGTCTTGAATGACAACACTTGGGTGGAGCTGA
GTGACTCCACCTGTCGGGTGGCTACACCCTTGCTCAGGGTATGCACTCCATGGTTTGCTCTATGGCCCACCATCCTGGATTGTCTCCCTGACACCAAGGC
TAAGGGACCCACTTTACTCACTTATCTGCTGGGCCTTGGAAGTATTTCAGTTCGGAACCCCAATTCTAACCTTAGCTTCTCAGGCCATTAAATGAAATCT
CATTTCTATGATGCTTCCTGTCACATCACTGTGCTGCTGAGAACATGAAGTCTGTGGGTGAATTGGTGGACGGGATCCAGAATCATTACTTGGCAGTGGA
TTATAGTGTGATGACTCATTTCCGGTGGTCTCCAGGAGACTTGGCTGGGAGCTTCTCTTGGAGTCTAGGGTTAGCCAGAGGCTACATGTTTTAGGCATCT
TAATTCATATTTTATCTAAAGGCATATAAATCCTTAAAAAAAATCATTTGACTTCATCCTTGCTCCCTACATCCAGCCAGTAACCATTGCTTTGTTTTAC
ATCGCGTGCTTCAGGCTTTACTACAGCCTACCTGGATTTTGCAGTAGCTTCTTAAACTGCTTAAACTTTGGATATTGCCCCAGCCAACACATTCTGCCAC
AGAGATCTCTCTGAGTTAAATGGGATTGTATCATGCCCCACACCCAAGCAGATAGAAACTGTCAATAGATACACTTAGAATGAATATGCATGGAATCAAA
TTACATTCAGAATCTACCACTATAGGTAGTGAATACAACAGGATAGCAGAGGCTGGGAAGGGTAATGGGGGTTGGGGGGTGGGAGGATAAAGGGGTTGGG
TAATGGGTGTAAAAATCTATAGAAGGAATATGATCTGTTGTTTGGTAGCACAATAGGGTAAATACAGTTAATAATTTATTGTATATTTCACAATAAAGGA
GTGGATTTGGAATGTTCTCAACACAAATGATAAATGTTTGAGGTGATGGATACCCCAATTACCCTGATTTGATCATTATACGTTGTATGTTTGTATCAAA
ATATCATATGTACCCCATAAATATGTACAACTATTATGTATCCATAAAAATTGGAAATAAACTACCACCATCTTTCTTCAGCCTATTTTCCTATCTCCTC
TCGCACCATACTAGGCACACAATCTCTGTACCTGTGCTGTCTTCCAAGCCATTGCTCATGTTTTAAGAAATATACTTATTGTTTAATATATCCTGTACCA
CTGTAGGATGACTGTAGTTAACAATAATGTGTAGTTTCAAATAGCTAATAGCTGGAAGGAAGTTGTTGAATGTTTCCAACATAAAGAAATGATAAGTGTT
TGAGATGATGGATATGCTAATTACCCTGATCTGATCACTACACATTATATGTATGGAAATATCATTGTGTACCCCATGAATATGGGCAATTATTATTTGT
TAATTAAAAAAATAAAAAAAAGACCCACCCACTGTTTAA
- refseq_RAB3IP.F1 (forward primer)
- refseq_RAB3IP.R1 (reverse primer)
- Single exon skipping
Frame 0
LSKPGQWRASLPQPRCRLAV*SQTAVLAISEIPWA*DPLSQVWDIVSWCAVS*AGLKSAIFGWE*PD
FPGTEVKR*RM*EAFKSARSTWTGIGRTHS*SI
*GSS*NGERSKYQAGNSRKTAKRSTRKN*CTSS
*SSCIEDTCIVQFSNITYAGAFARWKDTF*KGAY
KK*KHKQCYEWQSSGPQCDTANCKRLQRG*LIL
V**IPIVEG*AHNGQDVSFLRQNLPGRYLSMFN
ILKK*VGFSCSGGCGKQYSKH*TSGITTYPVCES
FCS*MRRTKKMCSHWPE*VL*TQN*IRGLKQLL
LYFSFLQIQDHFCM*LFYIHSIHSAGTRETAGC
*SDVLGGYAVEKRDVIGKAGLFQRGTLMLCVGPC
LNSPNN*KMAEYFYGYLIFISKE*A*DFFPLLQ
IALRSTMISFKLIYAVFAYSLVEHTMKNSRCTS
ECNL*LPKKKKT*NK*MLD*MCVHFLF*L*HGI*
G*QNVLNSNFQTTQ*LPSL*EARKKSEWIVLTF
QGPHL*NGFIFICFLYWVSKKILFEEILLLLQS
LKVTILIILLSVTERIPLFWLFIKI**KAVRFYP
RDVFLSVLI*CIHVLYVLTTILSLEGHRCK*V*
RVSKGFKGVWIE*MVRAKYMLIIEPLDLCIPNC
KTDSTGEIITKRFVVDM**V*KSKKKRETALVSV
*RKLLLIFLDSSLSAFRYFLLTYAYF*NKK*AF
FLLFKPKH*IYFPLGKPTHPNPCL*NFNII*LC
LEMRWFSVYFSYYNAVTSILICTLLNIVEFFHVD
AWR*NCVEIYMYF*MFDLHC*IAIQKS*SICIH
SSSVQEGWFSEDNIFFSPVQRFGQSYL*MTSAT
RLDGSPQTKGHWCMLW*KPSVPCLAQECEIEPEK
NFEPTILCSENSYSNVRALIRICTIKASEDFPY
KLKSLLEKVPK*KEKQIQEILYGLKER*SNTQK
KFVDDLKRINKK*D*RKSVYPLIINL**SIRGRM
LFNLIH*KHAL*N*CNRMTT*CRNYMWNYRLKC
D*NIFRKCDYLPDPTPFRKNFLNWKQEKKKP*K
ITIKEYKLWYIINS*FRNRASVVRHCGSCL*SQH
FGRQRQKDYLSCLSPGV*DGPGKNRETPFTHTH
THTHTHTLCP*TWEDEVGGLLEPRGSSPTWAT*
GDLVSKKKTKAKLQTVRQYLQHL*LVIA*YQECM
QKFYKPTKKDSVTEKQAKD*TRPSTQLEVHVGQ
*TLRGFHLSIRKT*IKMTMTCSNSFDW*K*RNT
KSSFGEGFSH*DHSHIADGGINWYIHCEKPFTRK
VGPGPVAHASWLWEAKVGGSLEPKSSRPA*AT*
GDHICTKRFF*ISWAWWCMPVVPATWEAEVEGL
LKPRRLRLQ*IMIVPLHSYLG*QSKIIP*KKKKS
IPMGQQFHFSVYT*EMLAQVPQITHIRMFWNKL
KCLFLGRCNVFTEWVIITWQQNE*IPATCSTIT
QNEKAILRKLYVT*YFSYKSQEQLKLNSCLGIDI
CDKTFKK**SSR*WLPLER*RRSKSMSKSLVMF
*SLG*VVGFGVVHLSLKVST*AGCSGACL*SQL
LGSLR*EDP*GQFKAIVCYDFTCE*LLYSNLGNV
DLAPL*KNSKTK*MHGQMNKRVMHGTSVVYYES
SIITSSVICAFIPKQKIKGKKIVELHLRERKGK
NSGLNLRLLA*AIAVY*DGEIHGGESLGMCITET
EIQCLTDQV*GAH*ASKWIC*AGIGCTNLNSVR
SVQEKIWGVVSHGIRWAL*GHFGDEVQH*ALSS
CDREAACKDERRSC*EEQGNRKGRTSMLIMFRRV
FLR*I*LPRLPILKKRRTLGQVFRSWFGAGVRA
WPNGDSSGLGVT*TYILV*VWLPKTGKVS*VAT
PLSSWSLSA*RQFTVFD*ASTLEEQDLVSEHWVL
VLKITCNLLRLHLLPSPPQESCVFLFCASSLKR
VCFYS*AFVFSGFCCCIFP*IKCFFYKTLLKRV
QCSMNLYLCLTFVLNRSAMAELSVA*AKFWGLF*
VPLFVIVTPIPVISKFHQLSPRHLKSVYLPPCP
LLPLCPSYYHLSPELLH*CLLSLHPLLPSYNH*
RQPQGSL*NENQIMSLPCLKPFEWLPIALRKKKK
KKNWPGAMAHACNPSTLGGRGGRIP*GW*FETC
LANMEKPCLY*KHKISQV*WRMPVIPATWEAES
GETLEPRRQRLW*VDITPLHSSLGNKSETPSEKK
KKKPKLNRKSSFHSGSC*QRNNNESFKKLHENL
QNLKKKCRRGLNLIKY*KN*NPS*RQLLKGAQV
HTQFTFGGTSEVMRTRF*SYRSQGQSRGIQGPHH
HIPRFNRSSSAFICICWSSLGNVNTKANPNHN*
IRLLFKRMILYRNSAKWGYQESWKM*DVKTIIR
KIRIIFVIH*EGGIST*ILFPAAGLCSQWSALDS
D**RFSSPPSNFLLNSLHFPQISAPGLHLVGSI
VFSHNVLFVLHSVLVYFSVCPSCF*TIASI*K*
GNLKSAFQAALF*NVPFRQH*AHSLE*QHLGGAE
*LHLSGGYTLAQGMHSMVCSMAHHPGLSP*HQG
*GTHFTHLSAGPWKYFSSEPQF*P*LLRPLNEI
SFL*CFLSHHCAAENMKSVGELVDGIQNHYLAVD
YSVMTHFRWSPGDLAGSFSWSLGLARGYMF*AS
*FIFYLKAYKSLKKII*LHPCSLHPASNHCFVL
HRVLQALLQPTWILQ*LLKLLKLWILPQPTHSAT
EISLS*MGLYHAPHPSR*KLSIDTLRMNMHGIK
LHSESTTIGSEYNRIAEAGKGNGGWGVGG*RGW
VMGVKIYRRNMICCLVAQ*GKYS**FIVYFTIKE
WIWNVLNTNDKCLR*WIPQLP*FDHYTLYVCIK
ISYVPHKYVQLLCIHKNWK*TTTIFLQPIFLSP
LAPY*AHNLCTCAVFQAIAHVLRNILIV*YILYH
CRMTVVNNNV*FQIANSWKEVVECFQHKEMISV
*DDGYANYPDLITTHYMYGNIIVYPMNMGNYYL
LIKKIKKRPTHCL
Frame 1
*ASLGNGGRPSPSLVAALQFDLRLLC*QSARFRGRRTL*ARCGI*SRGAPFLKPV*KAQYSDGSDP
IFQELKLKDEECERLSKVRDQLGQELEELTASLF
EEAHKMVREANIKQATAEKQLKEAQGKIDVLQA
EVAALKTLVLSSSPTSPTQEPLPGGKTPFKKGH
TRNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSL
YNEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLT
FSKSELASAVLEAVENNTLSIEPVGLQPIRFVK
ASAVECGGPKKCALTGQSKSCKHRIKLGDSSNYY
YISPFCRYRITSVCNFFTYIRYIQQGLVKQQDV
DQMFWEVMQLRKEMSLAKLGYFKEEL*CSAWDH
A*TPRITEKWLNIFMVT*YLFPRSEPKTFFPFCK
LL*EVP*FLLN*SMLCLLIL*LNTL*RIPGVLV
NVIYSCQKKKKPEINKC*IECVYIFSSSSDMAF
RVSRMY*IVIFKLHSSFLPCERQERSLSG*YSLS
KAPTSRMALFLSVFYIGFQKRFYLKKYFCCYKV
*KLLF*LFCSL*LKESLYFGYSLKYNRRQSDFI
PEMYS*VS*YSVFMFYMC*PLYCHWRDIDVNEFD
VCQRGLKGCGLNEWYVRSIC*L*NHLISAFQIV
KLTQLEKL*QRGLW*TCNKYRKAKRKEKLL*FL
FRESCC*YFWIVAFQLSDIFYLHMHIFETKSRLF
FCFLNLNIKYIFPWVNLHILIPVYRILT*FNCV
WR*GGFQFIFHIIML*RVSLSVHF*TLWSSFMW
MPGDKIVSRYICIFKCLICIARLPSRKVNQFVFT
AAVYKRAGFLKITFFSVLFRGLVNLTCR*LQPP
GWMGAHRQKDIGVCYGENHQYHA*LKNVKLNLK
KTLNLQFYVLKIVILM*GH**EYVPSKLQKIFRT
N*NHFWRKYLNKKRNKSRRYCTV*KKGNQILRK
SLLMT*KG*IKSKTKENQYTH***IFSNL*GEE
CFSTLYTRSMLFKINATG*RLDVETICGIID*NV
IETYLENVIIFLILLPLGRTS*TGSRKKKNHKR
*P*KNISYGIL*ILNLEIVHQ*LGIVAHACNPS
TLGGRGRRIT*AA*AQEFETGLGKIGKLHLHTHT
HTHTHTHCVHELGRMRWEDCLSPGVQVQLGQHR
ETLSLKKKLKLNYKL*GNICNIYN***LSIKNV
CRNSTNQQKRTVSQKNRQKTEPGLPHN*KCMWAN
KH*EVFISQSGKRKSR*Q*HVQIHSIGENEETQ
SQVLERVLVIRITHILLMGVSIGISTVKNHSLE
KLGQAQWLMPLGFGRPR*EDHLSPRVQDQLEQHR
ETTSAQKDFFELAGHGGACLWSQLLGKLRWKDC
LSPGG*GCSES*LCHCTLTLGDRVRSYLKKKKK
VYPWVSNFTFQYILEKCLHRSPRSHI*ECSGIN*
NVYF*EGVMCSQNG*LLHGSKMNEYQLLAAQ*L
RMKKQF*ENYM*HDTFLIKVKNN*N*TAV*ALT
YVTKLLKSNKVQDSGYLWRGRGGANL*VSHW*CF
SPWVRWWVLGWFICH*K*VHELGVVVRAYSPSY
LGV*DRKILEASSRL*CAMISPVNSYYIPTWAT
*TLPPFKKIQKQNKCMDK*IRELCMEHRWCIMNQ
ALLLAQLYVPSFQNKK*KVRKLLNCI*ERGKER
IQV*ILGFWLELLQFIEMGKYMVGKVWVCA*QR
QKFSV*QIKCEVPTEHQSGYVKQVLDVQI*IQ*G
QSRRKFGE*LAMGSDGRFRDTLEMKYSTEP*VP
VTEKQPAKTKGGAVRKSKATEKEEPAC*LCSGE
CFYAEFNCQDYQF*RRGGLLDKFLEVGLELG*EP
GLMETALDWESLRPTFWSRFGSQKLGRLVRWPL
LSLHGLSQLEDNLQSLTKHPHWKNKIWFLNIGS
*SLK*LATCYVFTYSHRHHKNPVCFCFVHPV*NG
SAFIHRLLFSVVFVVAFFPR*NVFSIRHCLKES
NAV*ICICV*LLCLTDLPWLNSQLLKQNSGAYS
RFLYLSLSLPFQLSANSISCLRDILNLSTSLHVH
CYHSAQAIIIFHLNSCTNVCCPCIHSCPPTITD
GSRRDLYKTKIR*CHFPA*SPLSGFPLHLEKKK
KKKTGQVRWLMPVIPALWEAEAGGSPEVGSSRPA
WPTWRNPVSTKNTKLVRCDGACL*SQLLGRLSQ
EKRSNPGGRGCGELTSRHCTPAWATRVKLRLKK
KKKNPNSIENQVFIVVVVNREITMKALKNSMKIC
KT*KKNVEED*T**NIKRIETLPKGSFSREHKF
THSLLLEERLRS*GLDSRATGLRDSLEGYRAPI
TTSPDLTAAAQLLSVSVGAL*EMSIPKQTQITTR
LDYYSRE*FSTETLQNGDIKRVGKCKT*RP*SG
KYASYLLFTEREEFPLKSYFQQLDCALSGVLWI
LINRDFLVLPATSFSILFTFRRSRHQGCILWAPL
CFHTMCYLSFTVFWFIFLFVHLVFEQLPAFKNE
EI*NLHFKLLFFKMCRFDNTEPTVLNDNTWVEL
SDSTCRVATPLLRVCTPWFALWPTILDCLPDTKA
KGPTLLTYLLGLGSISVRNPNSNLSFSGH*MKS
HFYDASCHITVLLRT*SLWVNWWTGSRIITWQW
IIV**LISGGLQETWLGASLGV*G*PEATCFRHL
NSYFI*RHINP*KKSFDFILAPYIQPVTIALFY
IACFRLYYSLPGFCSSFLNCLNFGYCPSQHILP
QRSL*VKWDCIMPHTQADRNCQ*IHLE*ICMESN
YIQNLPL*VVNTTG*QRLGRVMGVGGWEDKGVG
*WV*KSIEGI*SVVW*HNRVNTVNNLLYISQ*R
SGFGMFSTQMINV*GDGYPNYPDLIIIRCMFVSK
YHMYPINMYNYYVSIKIGNKLPPSFFSLFSYLL
SHHTRHTISVPVLSSKPLLMF*EIYLLFNISCT
TVG*L*LTIMCSFK*LIAGRKLLNVSNIKK**VF
EMMDMLITLI*SLHIICMEISLCTP*IWAIIIC
*LKK*KKDPPTV*
Frame 2
KQAWAMAGVPPPASLPPCSLISDCCASNQRDSVGVGPSEPGVGYSLVVRRFLSRSEKRNIRMGVTR
FSRN*S*KMKNVRGFQKCEINLDRNWKNSQLVY
LRKLIKW*EKQISSRQQQKNS*KKHKEKLMYFKL
K*LH*RHLYCPVLQHHLRRSLCQVERHLLKRGI
QEIKAQAVL*VAVIRTSV*YSQL*KTAKRLTYP
CIMNSDCGRMSPQWTGRVLS*TKSTRKISFHV*H
SQKVSWLQLFWRLWKTIL*ALNQWDYNLSGL*K
LLQLNAEDQKNVLSLARVSPVNTELN*GTQATI
IIFLLFADTGSLLYVTFLHTFDTFSRDS*NSRML
IRCFGRLCS*EKRCHWQSWVISKRNSDALRGTM
PELPE*LKNG*IFLWLLDIYFQGVSLRLFSPFA
NCSKKYHDFF*TDLCCVCLFFS*THYEEFQVY**
M*FIVAKKKKNLK*INVRLNVCTFSLLALTWHL
GLAECIK**FSNYTVASFLVRGKKEV*VDSTHF
PRPPPLEWLYFYLFSILGFKKDFI*RNTSAATKF
ESYYFNYSALCN*KNPFILVIH*NIIEGSQILS
QRCIPECLDIVYSCFICVDHYIVIGGT*M*MSL
TCVKGV*RGVD*MNGTCEVYADYRTT*SLHSKL*
N*LNWRNYNKEVCGRHVISIEKQKEKRNCFSFC
LEKAAVNIFG**PFSFQIFSTYICIFLKQKVGF
FFAF*T*TLNIFSLG*TYTS*SLFIEF*HNLIVF
GDEVVFSLFFIL*CCDEYPYLYTSEHCGVLSCG
CLEIKLCRDIYVFLNV*SALLDCHPEKLINLYS
QQQCTRGLVF*R*HFFQSCSEVWSILPVDDFSHQ
AGWEPTDKRTLVYVMVKTISTMPSSRM*N*T*K
KL*TYNFMF*K*LF*CEGINKNMYHQSFRRFSV
QTKITFGEST*IKRETNPGDTVRFERKVIKYSEK
VC**LKKDK*KVRLKKISIPINNKSLVIYKGKN
AFQPYTLEACSLKLMQQDDDLM*KLYVEL*IKM
*LKHI*KM*LSS*SYSL*EELLKLEAGKKKTIKD
NHKRI*VMVYYKFLI*KSCISS*ALWLMPVIPA
LWEAEAEGLLELLEPRSLRRAWEK*GNSIYTHT
HTHTHTHTVSMNLGG*GGRIA*AQGFKSNLGNIG
RPCL*KKN*S*TTNCEAISATFITSNSLVSRMY
AEILQTNKKGQCHRKTGKRLNQAFHTIRSACGP
INIKRFSSLNQENVNQDDNDMFKFIRLVKMKKHK
VKFWRGF*SLGSLTYC*WGYQLVYPL*KTIH*K
SWARPSGSCLLALGGQGRRIT*AQEFKTSLSNI
GRPHLHKKIFLN*LGMVVHACGPSYLGS*GGRIA
*AQEVEAAVNHDCATALLPWVTE*DHTLKKKKK
YTHGSAISLFSIYLRNACTGPPDHTYKNVLE*I
KMSIFRKV*CVHRMGDYYMAAK*MNTSYLQHNNS
E*KSNSEKTICDMILFL*KSRTTKTEQLFRH*H
M*QNF*KVIKFKIVVTSGEVEEEQIYE*VTGNV
LVPGLGGGFWGGSFVIKSKYMSWV*WCVLIVPAT
WESEIGRSLRPVQGYSVL*FHL*IATIFQPGQR
RPCPPLKKFKNKINAWTNE*ESYAWNIGGVL*I
KHYY*LSYMCLHSKTKNKR*ENC*IAFEREERKE
FRSES*AFGLSYCSLLRWGNTWWGKFGYVHNRD
RNSVFDRSSVRCPLSIKVDMLSRYWMYKSKFSK
VSPGENLGSS*PWDQMGALGTLWR*STALSPEFL
*QRSSLQRRKEELLGRARQQKRKNQHADYVQES
VSTLNLIAKITNSKEEEDSWTSF*KLVWSWGES
LA*WRQLWIGSHLDLHSGLGLAPKNWEG*LGGHS
SLFMVSLSLKTIYSL*LSIHTGRTRFGF*TLGL
SP*NNLQPVTSSLTPIATTRILCVFVLCIQSKT
GLLLFIGFCFQWFLLLHFSLDKMFFL*DTA*KSP
MQYEFVFVFNFCA*QICHG*TLSCLSKILGLIL
GSFICHCHSHSSYQQIPSAVSETS*ICLPPSMS
TATTLPKLLSSFT*TPALMSAVLASTPALLQSLT
AAAGIFIKRKSDNVTSLLKAL*VASHCT*KKKK
KKKLARCDGSCL*SQHFGRPRRADPLRLVVRDL
LGQHGETLSLLKTQN*SGVMAHACNPSYLGG*VR
RNARTQEAEVVVS*HHAIALQPGQQE*NSV*KK
KKKTQTQ*KIKFS*W*LLTEK*Q*KL*KTP*KF
AKLKKKM*KRTKLDKILKELKPFLKAASQGSTSS
HTVYFWRNV*GHED*ILELQVSGTVSRDTGPPS
PHPQI*PQQLSFYLYLLELSRKCQYQSKPKSQL
D*ITIQENDSLPKLCKMGISRELENVRRKDHNQE
NTHHICYSLRGRNFHLNPISSSWIVLSVECSGF
*LIEIF*SSQQLPSQFSSLSADLGTRVASCGLH
CVFTQCAICPSQCFGLFFCLSILFLNNCQHLKMR
KSKICISSCSFLKCAVSTTLSPQS*MTTLGWS*
VTPPVGWLHPCSGYALHGLLYGPPSWIVSLTPR
LRDPLYSLICWALEVFQFGTPILTLASQAIK*NL
ISMMLPVTSLCC*EHEVCG*IGGRDPESLLGSG
L*CDDSFPVVSRRLGWELLLESRVSQRLHVLGI
LIHILSKGI*ILKKNHLTSSLLPTSSQ*PLLCFT
SRASGFTTAYLDFAVAS*TA*TLDIAPANTFCH
RDLSELNGIVSCPTPKQIETVNRYT*NEYAWNQ
ITFRIYHYR**IQQDSRGWEG*WGLGGGRIKGLG
NGCKNL*KEYDLLFGSTIG*IQLIIYCIFHNKG
VDLECSQHK**MFEVMDTPITLI*SLYVVCLYQ
NIICTP*ICTTIMYP*KLEINYHHLSSAYFPISS
RTILGTQSLYLCCLPSHCSCFKKYTYCLIYPVP
L*DDCS*Q*CVVSNS**LEGSC*MFPT*RNDKC
LR*WIC*LP*SDHYTLYVWKYHCVPHEYGQLLFV
N*KNKKKTHPLF
Sequence NM_022456
GCTTCCGGCGCAGGCGCAGTCCCGCGTTCCCTCGGCGGCTGCCGGCGTAGTGAGCCCGCCGCCGTGGAGTGTAGCGGAAAGGGCTCGCCGTCCTCCTCCGTTTCTCGCTGCTTCGGGACGCGCTCTCTGCGGCTCTGTGAGCGCCCCTGAGCGCCGGCAGCGGCCGCGGTGGGTTCTTCAGGTTATCTTATGATGAGGCT
TTTGCTATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTGTATGAATCAGGAACTCAAG
AGCAGACTACCTCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTTCCTAC
ACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTC
ACAGCTGGATTAACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTG
ATGATATTTTTGGGTTGAGTACTGATAGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACT
CGCAAAAGCTCAGAGGGAACTGAAGTTAAAAGATGAAGAATGTGAGAGGCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCT
AGTCTATTTGAGGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAACAGCTAAAAGAAGCACAAGGAAAAATTGATGTAC
TTCAAGCTGAAGTAGCTGCATTGAAGACACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAGACACCTTTTAAAAA
GGGGCATACAAGAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGTCATCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGAC
TTATCCTTGTATAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTCTTAGACAAAATCTACCAGGAAGATATCTTTCCAT
GTTTAACATTCTCAAAAAGTGAGTTGGCTTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTACAACCTATCCGGTT
TGTGAAAGCTTCTGCAGTTGAATGCGGAGGACCAAAAAAATGTGCTCTCACTGGCCAGAGTAAGTCCTGTAAACACAGAATTAAATTAGGGGACTCAAGC
AACTATTATTATATTTCTCCTTTTTGCAGATACAGGATCACTTCTGTATGTAACTTTTTTACATACATTCGATACATTCAGCAGGGACTCGTGAAACAGC
AGGATGTTGATCAGATGTTTTGGGAGGTTATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTCTGATGCTCTGCGTG
GGACCATGCCTGAACTCCCCGAATAACTGAAAAATGGCTGAATATTTTTATGGTTACTTGATATTTATTTCCAAGGAGTGAGCCTAAGACTTTTTTCCCC
TTTTGCAAATTGCTCTAAGAAGTACCATGATTTCTTTTAAACTGATCTATGCTGTGTTTGCTTATTCTTTAGTTGAACACACTATGAAGAATTCCAGGTG
TACTAGTGAATGTAATTTATAGTTGCCAAAAAAAAAAAAAACCTGAAATAAATAAATGTTAGATTGAATGTGTGTACATTTTCTCTTCTAGCTCTGACAT
GGCATTTAGGGTTAGCAGAATGTATTAAATAGTAATTTTCAAACTACACAGTAGCTTCCTTCCTTGTGAGAGGCAAGAAAGAAGTCTGAGTGGATAGTAC
TCACTTTCCAAGGCCCCCACCTCTAGAATGGCTTTATTTTTATCTGTTTTCTATATTGGGTTTCAAAAAAGATTTTATTTGAAGAAATACTTCTGCTGCT
ACAAAGTTTGAAAGTTACTATTTTAATTATTCTGCTCTCTGTAACTGAAAGAATCCCTTTATTTTGGTTATTCATTAAAATATAATAGAAGGCAGTCAGA
TTTTATCCCAGAGATGTATTCCTGAGTGTCTTGATATAGTGTATTCATGTTTTATATGTGTTGACCACTATATTGTCATTGGAGGGACATAGATGTAAAT
GAGTTTGACGTGTGTCAAAGGGGTTTAAAGGGGTGTGGATTGAATGAATGGTACGTGCGAAGTATATGCTGATTATAGAACCACTTGATCTCTGCATTCC
AAATTGTAAAACTGACTCAACTGGAGAAATTATAACAAAGAGGTTTGTGGTAGACATGTAATAAGTATAGAAAAGCAAAAAGAAAAGAGAAACTGCTTTA
GTTTCTGTTTAGAGAAAGCTGCTGTTAATATTTTTGGATAGTAGCCTTTCAGCTTTCAGATATTTTCTACTTACATATGCATATTTTTGAAACAAAAAGT
AGGCTTTTTTTTTGCTTTTTAAACCTAAACATTAAATATATTTTCCCTTGGGTAAACCTACACATCCTAATCCCTGTTTATAGAATTTTAACATAATTTA
ATTGTGTTTGGAGATGAGGTGGTTTTCAGTTTATTTTTCATATTATAATGCTGTGACGAGTATCCTTATCTGTACACTTCTGAACATTGTGGAGTTCTTT
CATGTGGATGCCTGGAGATAAAATTGTGTCGAGATATATATGTATTTTTAAATGTTTGATCTGCATTGCTAGATTGCCATCCAGAAAAGTTAATCAATTT
GTATTCACAGCAGCAGTGTACAAGAGGGCTGGTTTTCTGAAGATAACATTTTTTTCAGTCCTGTTCAGAGGTTTGGTCAATCTTACCTGTAGATGACTTC
AGCCACCAGGCTGGATGGGAGCCCACAGACAAAAGGACATTGGTGTATGTTATGGTGAAAACCATCAGTACCATGCCTAGCTCAAGAATGTGAAATTGAA
CCTGAAAAAAACTTTGAACCTACAATTTTATGTTCTGAAAATAGTTATTCTAATGTGAGGGCATTAATAAGAATATGTACCATCAAAGCTTCAGAAGATT
TTCCGTACAAACTAAAATCACTTTTGGAGAAAGTACCTAAATAAAAAGAGAAACAAATCCAGGAGATACTGTACGGTTTGAAAGAAAGGTAATCAAATAC
TCAGAAAAAGTTTGTTGATGACTTAAAAAGGATAAATAAAAAGTAAGACTAAAGAAAATCAGTATACCCATTAATAATAAATCTTTAGTAATCTATAAGG
GGAAGAATGCTTTTCAACCTTATACACTAGAAGCATGCTCTTTAAAATTAATGCAACAGGATGACGACTTGATGTAGAAACTATATGTGGAATTATAGAT
TAAAATGTGATTGAAACATATTTAGAAAATGTGATTATCTTCCTGATCCTACTCCCTTTAGGAAGAACTTCTTAAACTGGAAGCAGGAAAAAAAAAAACC
ATAAAAGATAACCATAAAAGAATATAAGTTATGGTATATTATAAATTCTTAATTTAGAAATCGTGCATCAGTAGTTAGGCATTGTGGCTCATGCCTGTAA
TCCCAGCACTTTGGGAGGCAGAGGCAGAAGGATTACTTGAGCTGCTTGAGCCCAGGAGTTTGAGACGGGCCTGGGAAAAATAGGGAAACTCCATTTACAC
ACACACACACACACACACACACACACACACTGTGTCCATGAACTTGGGAGGATGAGGTGGGAGGATTGCTTGAGCCCAGGGGTTCAAGTCCAACTTGGGC
AACATAGGGAGACCTTGTCTCTAAAAAAAAAACTAAAGCTAAACTACAAACTGTGAGGCAATATCTGCAACATTTATAACTAGTAATAGCTTAGTATCAA
GAATGTATGCAGAAATTCTACAAACCAACAAAAAAGGACAGTGTCACAGAAAAACAGGCAAAAGACTGAACCAGGCCTTCCACACAATTAGAAGTGCATG
TGGGCCAATAAACATTAAGAGGTTTTCATCTCTCAATCAGGAAAACGTAAATCAAGATGACAATGACATGTTCAAATTCATTCGATTGGTGAAAATGAAG
AAACACAAAGTCAAGTTTTGGAGAGGGTTTTAGTCATTAGGATCACTCACATATTGCTGATGGGGGTATCAATTGGTATATCCACTGTGAAAAACCATTC
ACTAGAAAAGTTGGGCCAGGCCCAGTGGCTCATGCCTCTTGGCTTTGGGAGGCCAAGGTAGGAGGATCACTTGAGCCCAAGAGTTCAAGACCAGCTTGAG
CAACATAGGGAGACCACATCTGCACAAAAAGATTTTTTTGAATTAGCTGGGCATGGTGGTGCATGCCTGTGGTCCCAGCTACTTGGGAAGCTGAGGTGGA
AGGATTGCTTAAGCCCAGGAGGTTGAGGCTGCAGTGAATCATGATTGTGCCACTGCACTCTTACCTTGGGTGACAGAGTAAGATCATACCTTAAAAAAAA
AAAAAAAGTATACCCATGGGTCAGCAATTTCACTTTTCAGTATATACTTGAGAAATGCTTGCACAGGTCCCCCAGATCACACATATAAGAATGTTCTGGA
ATAAATTAAAATGTCTATTTTTAGGAAGGTGTAATGTGTTCACAGAATGGGTGATTATTACATGGCAGCAAAATGAATGAATACCAGCTACTTGCAGCAC
AATAACTCAGAATGAAAAAGCAATTCTGAGAAAACTATATGTGACATGATACTTTTCTTATAAAAGTCAAGAACAACTAAAACTGAACAGCTGTTTAGGC
ATTGACATATGTGACAAAACTTTTAAAAAGTAATAAAGTTCAAGATAGTGGTTACCTCTGGAGAGGTAGAGGAGGAGCAAATCTATGAGTAAGTCACTGG
TAATGTTTTAGTCCCTGGGTTAGGTGGTGGGTTTTGGGGTGGTTCATTTGTCATTAAAAGTAAGTACATGAGCTGGGTGTAGTGGTGCGTGCTTATAGTC
CCAGCTACTTGGGAGTCTGAGATAGGAAGATCCTTGAGGCCAGTTCAAGGCTATAGTGTGCTATGATTTCACCTGTGAATAGCTACTATATTCCAACCTG
GGCAACGTAGACCTTGCCCCCCTTTAAAAAAATTCAAAAACAAAATAAATGCATGGACAAATGAATAAGAGAGTTATGCATGGAACATCGGTGGTGTATT
ATGAATCAAGCATTATTACTAGCTCAGTTATATGTGCCTTCATTCCAAAACAAAAAATAAAAGGTAAGAAAATTGTTGAATTGCATTTGAGAGAGAGGAA
AGGAAAGAATTCAGGTCTGAATCTTAGGCTTTTGGCTTGAGCTATTGCAGTTTATTGAGATGGGGAAATACATGGTGGGGAAAGTTTGGGTATGTGCATA
ACAGAGACAGAAATTCAGTGTTTGACAGATCAAGTGTGAGGTGCCCACTGAGCATCAAAGTGGATATGTTAAGCAGGTATTGGATGTACAAATCTAAATT
CAGTAAGGTCAGTCCAGGAGAAAATTTGGGGAGTAGTTAGCCATGGGATCAGATGGGCGCTTTAGGGACACTTTGGAGATGAAGTACAGCACTGAGCCCT
GAGTTCCTGTGACAGAGAAGCAGCCTGCAAAGACGAAAGGAGGAGCTGTTAGGAAGAGCAAGGCAACAGAAAAGGAAGAACCAGCATGCTGATTATGTTC
AGGAGAGTGTTTCTACGCTGAATTTAATTGCCAAGATTACCAATTCTAAAGAAGAGGAGGACTCTTGGACAAGTTTTTAGAAGTTGGTTTGGAGCTGGGG
TGAGAGCCTGGCCTAATGGAGACAGCTCTGGATTGGGAGTCACTTAGACCTACATTCTGGTCTAGGTTTGGCTCCCAAAAACTGGGAAGGTTAGTTAGGT
GGCCACTCCTCTCTCTTCATGGTCTCTCTCAGCTTGAAGACAATTTACAGTCTTTGACTAAGCATCCACACTGGAAGAACAAGATTTGGTTTCTGAACAT
TGGGTCTTAGTCCTTAAAATAACTTGCAACCTGTTACGTCTTCACTTACTCCCATCGCCACCACAAGAATCCTGTGTGTTTTTGTTTTGTGCATCCAGTC
TAAAACGGGTCTGCTTTTATTCATAGGCTTTTGTTTTCAGTGGTTTTTGTTGTTGCATTTTTCCCTAGATAAAATGTTTTTTCTATAAGACACTGCTTAA
AAGAGTCCAATGCAGTATGAATTTGTATTTGTGTTTAACTTTTGTGCTTAACAGATCTGCCATGGCTGAACTCTCAGTTGCTTAAGCAAAATTCTGGGGC
TTATTCTAGGTTCCTTTATTTGTCATTGTCACTCCCATTCCAGTTATCAGCAAATTCCATCAGCTGTCTCCGAGACATCTTAAATCTGTCTACCTCCCTC
CATGTCCACTGCTACCACTCTGCCCAAGCTATTATCATCTTTCACCTGAACTCCTGCACTAATGTCTGCTGTCCTTGCATCCACTCCTGCCCTCCTACAA
TCACTGACGGCAGCCGCAGGGATCTTTATAAAACGAAAATCAGATAATGTCACTTCCCTGCTTAAAGCCCTTTGAGTGGCTTCCCATTGCACTTAGAAAA
AAAAAAAAAAAAAAAAACTGGCCAGGTGCGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCCCCTGAGGTTGGTAGTTCG
AGACCTGCTTGGCCAACATGGAGAAACCCTGTCTCTACTAAAAACACAAAATTAGTCAGGTGTGATGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGC
TGAGTCAGGAGAAACGCTCGAACCCAGGAGGCAGAGGTTGTGGTGAGTTGACATCACGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCT
GAAAAAAAAAAAAAAAAACCCAAACTCAATAGAAAATCAAGTTTTCATAGTGGTAGTTGTTAACAGAGAAATAACAATGAAAGCTTTAAAAAACTCCATG
AAAATTTGCAAAACTTAAAAAAAAAATGTAGAAGAGGACTAAACTTGATAAAATATTAAAAGAATTGAAACCCTTCCTAAAGGCAGCTTCTCAAGGGAGC
ACAAGTTCACACACAGTTTACTTTTGGAGGAACGTCTGAGGTCATGAGGACTAGATTCTAGAGCTACAGGTCTCAGGGACAGTCTCGAGGGATACAGGGC
CCCCATCACCACATCCCCAGATTTAACCGCAGCAGCTCAGCTTTTATCTGTATCTGTTGGAGCTCTCTAGGAAATGTCAATACCAAAGCAAACCCAAATC
ACAACTAGATTAGATTACTATTCAAGAGAATGATTCTCTACCGAAACTCTGCAAAATGGGGATATCAAGAGAGTTGGAAAATGTAAGACGTAAAGACCAT
AATCAGGAAAATACGCATCATATTTGTTATTCACTGAGAGGGAGGAATTTCCACTTAAATCCTATTTCCAGCAGCTGGATTGTGCTCTCAGTGGAGTGCT
CTGGATTCTGATTAATAGAGATTTTCTAGTCCTCCCAGCAACTTCCTTCTCAATTCTCTTCACTTTCCGCAGATCTCGGCACCAGGGTTGCATCTTGTGG
GCTCCATTGTGTTTTCACACAATGTGCTATTTGTCCTTCACAGTGTTTTGGTTTATTTTTCTGTTTGTCCATCTTGTTTTTGAACAATTGCCAGCATTTA
AAAATGAGGAAATCTAAAATCTGCATTTCAAGCTGCTCTTTTTTAAAATGTGCCGTTTCGACAACACTGAGCCCACAGTCTTGAATGACAACACTTGGGT
GGAGCTGAGTGACTCCACCTGTCGGGTGGCTACACCCTTGCTCAGGGTATGCACTCCATGGTTTGCTCTATGGCCCACCATCCTGGATTGTCTCCCTGAC
ACCAAGGCTAAGGGACCCACTTTACTCACTTATCTGCTGGGCCTTGGAAGTATTTCAGTTCGGAACCCCAATTCTAACCTTAGCTTCTCAGGCCATTAAA
TGAAATCTCATTTCTATGATGCTTCCTGTCACATCACTGTGCTGCTGAGAACATGAAGTCTGTGGGTGAATTGGTGGACGGGATCCAGAATCATTACTTG
GCAGTGGATTATAGTGTGATGACTCATTTCCGGTGGTCTCCAGGAGACTTGGCTGGGAGCTTCTCTTGGAGTCTAGGGTTAGCCAGAGGCTACATGTTTT
AGGCATCTTAATTCATATTTTATCTAAAGGCATATAAATCCTTAAAAAAAATCATTTGACTTCATCCTTGCTCCCTACATCCAGCCAGTAACCATTGCTT
TGTTTTACATCGCGTGCTTCAGGCTTTACTACAGCCTACCTGGATTTTGCAGTAGCTTCTTAAACTGCTTAAACTTTGGATATTGCCCCAGCCAACACAT
TCTGCCACAGAGATCTCTCTGAGTTAAATGGGATTGTATCATGCCCCACACCCAAGCAGATAGAAACTGTCAATAGATACACTTAGAATGAATATGCATG
GAATCAAATTACATTCAGAATCTACCACTATAGGTAGTGAATACAACAGGATAGCAGAGGCTGGGAAGGGTAATGGGGGTTGGGGGGTGGGAGGATAAAG
GGGTTGGGTAATGGGTGTAAAAATCTATAGAAGGAATATGATCTGTTGTTTGGTAGCACAATAGGGTAAATACAGTTAATAATTTATTGTATATTTCACA
ATAAAGGAGTGGATTTGGAATGTTCTCAACACAAATGATAAATGTTTGAGGTGATGGATACCCCAATTACCCTGATTTGATCATTATACGTTGTATGTTT
GTATCAAAATATCATATGTACCCCATAAATATGTACAACTATTATGTATCCATAAAAATTGGAAATAAACTACCACCATCTTTCTTCAGCCTATTTTCCT
ATCTCCTCTCGCACCATACTAGGCACACAATCTCTGTACCTGTGCTGTCTTCCAAGCCATTGCTCATGTTTTAAGAAATATACTTATTGTTTAATATATC
CTGTACCACTGTAGGATGACTGTAGTTAACAATAATGTGTAGTTTCAAATAGCTAATAGCTGGAAGGAAGTTGTTGAATGTTTCCAACATAAAGAAATGA
TAAGTGTTTGAGATGATGGATATGCTAATTACCCTGATCTGATCACTACACATTATATGTATGGAAATATCATTGTGTACCCCATGAATATGGGCAATTA
TTATTTGTTAATTAAAAAAATAAAAAAAAGACCCACCCACTGTTTAA
- refseq_RAB3IP.F1 (forward primer)
- refseq_RAB3IP.R1 (reverse primer)
- Single exon skipping
Frame 0
ASGAGAVPRSLGGCRRSEPAAVECSGKGSPSSSVSRCFGTRSLRLCERP*APAAAAVGSSGYLMMRL
LLWLMIPWKASMK*TLLHLLLRTFLVCMNQELK
SRLPHQVSSTGHTLQLYPLYLSRQMH*MFLNFL
HNPCIHPPDV*IVRKYLVSAFMLQTQPLALPLES
QLD*LN*LQERTTIMQRESFYRVLL*QRLAMAV
MIFLG*VLIVCLVYEAHLFWKLEKRAMND*KKN
SQKLRGN*S*KMKNVRGFQKCEINLDRNWKNSQL
VYLRKLIKW*EKQISSRQQQKNS*KKHKEKLMY
FKLK*LH*RHLYCPVLQHHLRRSLCQVERHLLK
RGIQEIKAQAVL*VAVIRTSV*YSQL*KTAKRLT
YPCIMNSDCGRMSPQWTGRVLS*TKSTRKISFH
V*HSQKVSWLQLFWRLWKTIL*ALNQWDYNLSG
L*KLLQLNAEDQKNVLSLARVSPVNTELN*GTQA
TIIIFLLFADTGSLLYVTFLHTFDTFSRDS*NS
RMLIRCFGRLCS*EKRCHWQSWVISKRNSDALR
GTMPELPE*LKNG*IFLWLLDIYFQGVSLRLFSP
FANCSKKYHDFF*TDLCCVCLFFS*THYEEFQV
Y**M*FIVAKKKKNLK*INVRLNVCTFSLLALT
WHLGLAECIK**FSNYTVASFLVRGKKEV*VDST
HFPRPPPLEWLYFYLFSILGFKKDFI*RNTSAA
TKFESYYFNYSALCN*KNPFILVIH*NIIEGSQ
ILSQRCIPECLDIVYSCFICVDHYIVIGGT*M*M
SLTCVKGV*RGVD*MNGTCEVYADYRTT*SLHS
KL*N*LNWRNYNKEVCGRHVISIEKQKEKRNCF
SFCLEKAAVNIFG**PFSFQIFSTYICIFLKQKV
GFFFAF*T*TLNIFSLG*TYTS*SLFIEF*HNL
IVFGDEVVFSLFFIL*CCDEYPYLYTSEHCGVL
SCGCLEIKLCRDIYVFLNV*SALLDCHPEKLINL
YSQQQCTRGLVF*R*HFFQSCSEVWSILPVDDF
SHQAGWEPTDKRTLVYVMVKTISTMPSSRM*N*
T*KKL*TYNFMF*K*LF*CEGINKNMYHQSFRRF
SVQTKITFGEST*IKRETNPGDTVRFERKVIKY
SEKVC**LKKDK*KVRLKKISIPINNKSLVIYK
GKNAFQPYTLEACSLKLMQQDDDLM*KLYVEL*I
KM*LKHI*KM*LSS*SYSL*EELLKLEAGKKKT
IKDNHKRI*VMVYYKFLI*KSCISS*ALWLMPV
IPALWEAEAEGLLELLEPRSLRRAWEK*GNSIYT
HTHTHTHTHTVSMNLGG*GGRIA*AQGFKSNLG
NIGRPCL*KKN*S*TTNCEAISATFITSNSLVS
RMYAEILQTNKKGQCHRKTGKRLNQAFHTIRSAC
GPINIKRFSSLNQENVNQDDNDMFKFIRLVKMK
KHKVKFWRGF*SLGSLTYC*WGYQLVYPL*KTI
H*KSWARPSGSCLLALGGQGRRIT*AQEFKTSLS
NIGRPHLHKKIFLN*LGMVVHACGPSYLGS*GG
RIA*AQEVEAAVNHDCATALLPWVTE*DHTLKK
KKKYTHGSAISLFSIYLRNACTGPPDHTYKNVLE
*IKMSIFRKV*CVHRMGDYYMAAK*MNTSYLQH
NNSE*KSNSEKTICDMILFL*KSRTTKTEQLFR
H*HM*QNF*KVIKFKIVVTSGEVEEEQIYE*VTG
NVLVPGLGGGFWGGSFVIKSKYMSWV*WCVLIV
PATWESEIGRSLRPVQGYSVL*FHL*IATIFQP
GQRRPCPPLKKFKNKINAWTNE*ESYAWNIGGVL
*IKHYY*LSYMCLHSKTKNKR*ENC*IAFEREE
RKEFRSES*AFGLSYCSLLRWGNTWWGKFGYVH
NRDRNSVFDRSSVRCPLSIKVDMLSRYWMYKSKF
SKVSPGENLGSS*PWDQMGALGTLWR*STALSP
EFL*QRSSLQRRKEELLGRARQQKRKNQHADYV
QESVSTLNLIAKITNSKEEEDSWTSF*KLVWSWG
ESLA*WRQLWIGSHLDLHSGLGLAPKNWEG*LG
GHSSLFMVSLSLKTIYSL*LSIHTGRTRFGF*T
LGLSP*NNLQPVTSSLTPIATTRILCVFVLCIQS
KTGLLLFIGFCFQWFLLLHFSLDKMFFL*DTA*
KSPMQYEFVFVFNFCA*QICHG*TLSCLSKILG
LILGSFICHCHSHSSYQQIPSAVSETS*ICLPPS
MSTATTLPKLLSSFT*TPALMSAVLASTPALLQ
SLTAAAGIFIKRKSDNVTSLLKAL*VASHCT*K
KKKKKKLARCDGSCL*SQHFGRPRRADPLRLVVR
DLLGQHGETLSLLKTQN*SGVMAHACNPSYLGG
*VRRNARTQEAEVVVS*HHAIALQPGQQE*NSV
*KKKKKTQTQ*KIKFS*W*LLTEK*Q*KL*KTP*
KFAKLKKKM*KRTKLDKILKELKPFLKAASQGS
TSSHTVYFWRNV*GHED*ILELQVSGTVSRDTG
PPSPHPQI*PQQLSFYLYLLELSRKCQYQSKPKS
QLD*ITIQENDSLPKLCKMGISRELENVRRKDH
NQENTHHICYSLRGRNFHLNPISSSWIVLSVEC
SGF*LIEIF*SSQQLPSQFSSLSADLGTRVASCG
LHCVFTQCAICPSQCFGLFFCLSILFLNNCQHL
KMRKSKICISSCSFLKCAVSTTLSPQS*MTTLG
WS*VTPPVGWLHPCSGYALHGLLYGPPSWIVSLT
PRLRDPLYSLICWALEVFQFGTPILTLASQAIK
*NLISMMLPVTSLCC*EHEVCG*IGGRDPESLL
GSGL*CDDSFPVVSRRLGWELLLESRVSQRLHVL
GILIHILSKGI*ILKKNHLTSSLLPTSSQ*PLL
CFTSRASGFTTAYLDFAVAS*TA*TLDIAPANT
FCHRDLSELNGIVSCPTPKQIETVNRYT*NEYAW
NQITFRIYHYR**IQQDSRGWEG*WGLGGGRIK
GLGNGCKNL*KEYDLLFGSTIG*IQLIIYCIFH
NKGVDLECSQHK**MFEVMDTPITLI*SLYVVCL
YQNIICTP*ICTTIMYP*KLEINYHHLSSAYFP
ISSRTILGTQSLYLCCLPSHCSCFKKYTYCLIY
PVPL*DDCS*Q*CVVSNS**LEGSC*MFPT*RND
KCLR*WIC*LP*SDHYTLYVWKYHCVPHEYGQL
LFVN*KNKKKTHPLF
Frame 1
LPAQAQSRVPSAAAGVVSPPPWSVAERARRPPPFLAASGRALCGSVSAPERRQRPRWVLQVIL**G
FCYG**SLGRLP*SKPCFTYFSGPSWCV*IRNSR
ADYLTKCHLPATPFSFILCTYPGKCIRCF*TSY
TTRVFIPQTFKLCGNI*YQLSCYRPSPLLYLWS
HSWIN*INYKKGQL*CRERVFTGCYYNRGLRWQ*
*YFWVEY**SVSFTKPICFGS*RKGL*TIKRRT
RKSSEGTEVKR*RM*EAFKSARSTWTGIGRTHS
*SI*GSS*NGERSKYQAGNSRKTAKRSTRKN*CT
SS*SSCIEDTCIVQFSNITYAGAFARWKDTF*K
GAYKK*KHKQCYEWQSSGPQCDTANCKRLQRG*
LILV**IPIVEG*AHNGQDVSFLRQNLPGRYLSM
FNILKK*VGFSCSGGCGKQYSKH*TSGITTYPV
CESFCS*MRRTKKMCSHWPE*VL*TQN*IRGLK
QLLLYFSFLQIQDHFCM*LFYIHSIHSAGTRETA
GC*SDVLGGYAVEKRDVIGKAGLFQRGTLMLCV
GPCLNSPNN*KMAEYFYGYLIFISKE*A*DFFP
LLQIALRSTMISFKLIYAVFAYSLVEHTMKNSRC
TSECNL*LPKKKKT*NK*MLD*MCVHFLF*L*H
GI*G*QNVLNSNFQTTQ*LPSL*EARKKSEWIV
LTFQGPHL*NGFIFICFLYWVSKKILFEEILLLL
QSLKVTILIILLSVTERIPLFWLFIKI**KAVR
FYPRDVFLSVLI*CIHVLYVLTTILSLEGHRCK
*V*RVSKGFKGVWIE*MVRAKYMLIIEPLDLCIP
NCKTDSTGEIITKRFVVDM**V*KSKKKRETAL
VSV*RKLLLIFLDSSLSAFRYFLLTYAYF*NKK
*AFFLLFKPKH*IYFPLGKPTHPNPCL*NFNII*
LCLEMRWFSVYFSYYNAVTSILICTLLNIVEFF
HVDAWR*NCVEIYMYF*MFDLHC*IAIQKS*SI
CIHSSSVQEGWFSEDNIFFSPVQRFGQSYL*MTS
ATRLDGSPQTKGHWCMLW*KPSVPCLAQECEIE
PEKNFEPTILCSENSYSNVRALIRICTIKASED
FPYKLKSLLEKVPK*KEKQIQEILYGLKER*SNT
QKKFVDDLKRINKK*D*RKSVYPLIINL**SIR
GRMLFNLIH*KHAL*N*CNRMTT*CRNYMWNYR
LKCD*NIFRKCDYLPDPTPFRKNFLNWKQEKKKP
*KITIKEYKLWYIINS*FRNRASVVRHCGSCL*
SQHFGRQRQKDYLSCLSPGV*DGPGKNRETPFT
HTHTHTHTHTLCP*TWEDEVGGLLEPRGSSPTWA
T*GDLVSKKKTKAKLQTVRQYLQHL*LVIA*YQ
ECMQKFYKPTKKDSVTEKQAKD*TRPSTQLEVH
VGQ*TLRGFHLSIRKT*IKMTMTCSNSFDW*K*R
NTKSSFGEGFSH*DHSHIADGGINWYIHCEKPF
TRKVGPGPVAHASWLWEAKVGGSLEPKSSRPA*
AT*GDHICTKRFF*ISWAWWCMPVVPATWEAEVE
GLLKPRRLRLQ*IMIVPLHSYLG*QSKIIP*KK
KKSIPMGQQFHFSVYT*EMLAQVPQITHIRMFW
NKLKCLFLGRCNVFTEWVIITWQQNE*IPATCST
ITQNEKAILRKLYVT*YFSYKSQEQLKLNSCLG
IDICDKTFKK**SSR*WLPLER*RRSKSMSKSL
VMF*SLG*VVGFGVVHLSLKVST*AGCSGACL*S
QLLGSLR*EDP*GQFKAIVCYDFTCE*LLYSNL
GNVDLAPL*KNSKTK*MHGQMNKRVMHGTSVVY
YESSIITSSVICAFIPKQKIKGKKIVELHLRERK
GKNSGLNLRLLA*AIAVY*DGEIHGGESLGMCI
TETEIQCLTDQV*GAH*ASKWIC*AGIGCTNLN
SVRSVQEKIWGVVSHGIRWAL*GHFGDEVQH*AL
SSCDREAACKDERRSC*EEQGNRKGRTSMLIMF
RRVFLR*I*LPRLPILKKRRTLGQVFRSWFGAG
VRAWPNGDSSGLGVT*TYILV*VWLPKTGKVS*V
ATPLSSWSLSA*RQFTVFD*ASTLEEQDLVSEH
WVLVLKITCNLLRLHLLPSPPQESCVFLFCASS
LKRVCFYS*AFVFSGFCCCIFP*IKCFFYKTLLK
RVQCSMNLYLCLTFVLNRSAMAELSVA*AKFWG
LF*VPLFVIVTPIPVISKFHQLSPRHLKSVYLP
PCPLLPLCPSYYHLSPELLH*CLLSLHPLLPSYN
H*RQPQGSL*NENQIMSLPCLKPFEWLPIALRK
KKKKKNWPGAMAHACNPSTLGGRGGRIP*GW*F
ETCLANMEKPCLY*KHKISQV*WRMPVIPATWEA
ESGETLEPRRQRLW*VDITPLHSSLGNKSETPS
EKKKKKPKLNRKSSFHSGSC*QRNNNESFKKLH
ENLQNLKKKCRRGLNLIKY*KN*NPS*RQLLKGA
QVHTQFTFGGTSEVMRTRF*SYRSQGQSRGIQG
PHHHIPRFNRSSSAFICICWSSLGNVNTKANPN
HN*IRLLFKRMILYRNSAKWGYQESWKM*DVKTI
IRKIRIIFVIH*EGGIST*ILFPAAGLCSQWSA
LDSD**RFSSPPSNFLLNSLHFPQISAPGLHLV
GSIVFSHNVLFVLHSVLVYFSVCPSCF*TIASI*
K*GNLKSAFQAALF*NVPFRQH*AHSLE*QHLG
GAE*LHLSGGYTLAQGMHSMVCSMAHHPGLSP*
HQG*GTHFTHLSAGPWKYFSSEPQF*P*LLRPLN
EISFL*CFLSHHCAAENMKSVGELVDGIQNHYL
AVDYSVMTHFRWSPGDLAGSFSWSLGLARGYMF
*AS*FIFYLKAYKSLKKII*LHPCSLHPASNHCF
VLHRVLQALLQPTWILQ*LLKLLKLWILPQPTH
SATEISLS*MGLYHAPHPSR*KLSIDTLRMNMH
GIKLHSESTTIGSEYNRIAEAGKGNGGWGVGG*R
GWVMGVKIYRRNMICCLVAQ*GKYS**FIVYFT
IKEWIWNVLNTNDKCLR*WIPQLP*FDHYTLYV
CIKISYVPHKYVQLLCIHKNWK*TTTIFLQPIFL
SPLAPY*AHNLCTCAVFQAIAHVLRNILIV*YI
LYHCRMTVVNNNV*FQIANSWKEVVECFQHKEM
ISV*DDGYANYPDLITTHYMYGNIIVYPMNMGNY
YLLIKKIKKRPTHCL
Frame 2
FRRRRSPAFPRRLPA**ARRRGV*RKGLAVLLRFSLLRDALSAAL*APLSAGSGRGGFFRLSYDEA
FAMANDPLEGFHEVNLASPTSPDLLGVYESGTQ
EQTTSPSVIYRPHPSALSSVPIQANALDVSELPT
QPVYSSPRRLNCAEISSISFHVTDPAPCSTSGV
TAGLTKLTTRKDNYNAEREFLQGATITEACDGS
DDIFGLSTDSLSRLRSPSVLEVREKGYERLKEEL
AKAQRELKLKDEECERLSKVRDQLGQELEELTA
SLFEEAHKMVREANIKQATAEKQLKEAQGKIDV
LQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKK
GHTRNKSTSSAMSGSHQDLSVIQPIVKDCKEAD
LSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFP
CLTFSKSELASAVLEAVENNTLSIEPVGLQPIRF
VKASAVECGGPKKCALTGQSKSCKHRIKLGDSS
NYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQ
QDVDQMFWEVMQLRKEMSLAKLGYFKEEL*CSAW
DHA*TPRITEKWLNIFMVT*YLFPRSEPKTFFP
FCKLL*EVP*FLLN*SMLCLLIL*LNTL*RIPG
VLVNVIYSCQKKKKPEINKC*IECVYIFSSSSDM
AFRVSRMY*IVIFKLHSSFLPCERQERSLSG*Y
SLSKAPTSRMALFLSVFYIGFQKRFYLKKYFCC
YKV*KLLF*LFCSL*LKESLYFGYSLKYNRRQSD
FIPEMYS*VS*YSVFMFYMC*PLYCHWRDIDVN
EFDVCQRGLKGCGLNEWYVRSIC*L*NHLISAF
QIVKLTQLEKL*QRGLW*TCNKYRKAKRKEKLL*
FLFRESCC*YFWIVAFQLSDIFYLHMHIFETKS
RLFFCFLNLNIKYIFPWVNLHILIPVYRILT*F
NCVWR*GGFQFIFHIIML*RVSLSVHF*TLWSSF
MWMPGDKIVSRYICIFKCLICIARLPSRKVNQF
VFTAAVYKRAGFLKITFFSVLFRGLVNLTCR*L
QPPGWMGAHRQKDIGVCYGENHQYHA*LKNVKLN
LKKTLNLQFYVLKIVILM*GH**EYVPSKLQKI
FRTN*NHFWRKYLNKKRNKSRRYCTV*KKGNQI
LRKSLLMT*KG*IKSKTKENQYTH***IFSNL*G
EECFSTLYTRSMLFKINATG*RLDVETICGIID
*NVIETYLENVIIFLILLPLGRTS*TGSRKKKN
HKR*P*KNISYGIL*ILNLEIVHQ*LGIVAHACN
PSTLGGRGRRIT*AA*AQEFETGLGKIGKLHLH
THTHTHTHTHCVHELGRMRWEDCLSPGVQVQLG
QHRETLSLKKKLKLNYKL*GNICNIYN***LSIK
NVCRNSTNQQKRTVSQKNRQKTEPGLPHN*KCM
WANKH*EVFISQSGKRKSR*Q*HVQIHSIGENE
ETQSQVLERVLVIRITHILLMGVSIGISTVKNHS
LEKLGQAQWLMPLGFGRPR*EDHLSPRVQDQLE
QHRETTSAQKDFFELAGHGGACLWSQLLGKLRW
KDCLSPGG*GCSES*LCHCTLTLGDRVRSYLKKK
KKVYPWVSNFTFQYILEKCLHRSPRSHI*ECSG
IN*NVYF*EGVMCSQNG*LLHGSKMNEYQLLAA
Q*LRMKKQF*ENYM*HDTFLIKVKNN*N*TAV*A
LTYVTKLLKSNKVQDSGYLWRGRGGANL*VSHW
*CFSPWVRWWVLGWFICH*K*VHELGVVVRAYS
PSYLGV*DRKILEASSRL*CAMISPVNSYYIPTW
AT*TLPPFKKIQKQNKCMDK*IRELCMEHRWCI
MNQALLLAQLYVPSFQNKK*KVRKLLNCI*ERG
KERIQV*ILGFWLELLQFIEMGKYMVGKVWVCA*
QRQKFSV*QIKCEVPTEHQSGYVKQVLDVQI*I
Q*GQSRRKFGE*LAMGSDGRFRDTLEMKYSTEP
*VPVTEKQPAKTKGGAVRKSKATEKEEPAC*LCS
GECFYAEFNCQDYQF*RRGGLLDKFLEVGLELG
*EPGLMETALDWESLRPTFWSRFGSQKLGRLVR
WPLLSLHGLSQLEDNLQSLTKHPHWKNKIWFLNI
GS*SLK*LATCYVFTYSHRHHKNPVCFCFVHPV
*NGSAFIHRLLFSVVFVVAFFPR*NVFSIRHCL
KESNAV*ICICV*LLCLTDLPWLNSQLLKQNSGA
YSRFLYLSLSLPFQLSANSISCLRDILNLSTSL
HVHCYHSAQAIIIFHLNSCTNVCCPCIHSCPPT
ITDGSRRDLYKTKIR*CHFPA*SPLSGFPLHLEK
KKKKKTGQVRWLMPVIPALWEAEAGGSPEVGSS
RPAWPTWRNPVSTKNTKLVRCDGACL*SQLLGR
LSQEKRSNPGGRGCGELTSRHCTPAWATRVKLRL
KKKKKNPNSIENQVFIVVVVNREITMKALKNSM
KICKT*KKNVEED*T**NIKRIETLPKGSFSRE
HKFTHSLLLEERLRS*GLDSRATGLRDSLEGYRA
PITTSPDLTAAAQLLSVSVGAL*EMSIPKQTQI
TTRLDYYSRE*FSTETLQNGDIKRVGKCKT*RP
*SGKYASYLLFTEREEFPLKSYFQQLDCALSGVL
WILINRDFLVLPATSFSILFTFRRSRHQGCILW
APLCFHTMCYLSFTVFWFIFLFVHLVFEQLPAF
KNEEI*NLHFKLLFFKMCRFDNTEPTVLNDNTWV
ELSDSTCRVATPLLRVCTPWFALWPTILDCLPD
TKAKGPTLLTYLLGLGSISVRNPNSNLSFSGH*
MKSHFYDASCHITVLLRT*SLWVNWWTGSRIITW
QWIIV**LISGGLQETWLGASLGV*G*PEATCF
RHLNSYFI*RHINP*KKSFDFILAPYIQPVTIA
LFYIACFRLYYSLPGFCSSFLNCLNFGYCPSQHI
LPQRSL*VKWDCIMPHTQADRNCQ*IHLE*ICM
ESNYIQNLPL*VVNTTG*QRLGRVMGVGGWEDK
GVG*WV*KSIEGI*SVVW*HNRVNTVNNLLYISQ
*RSGFGMFSTQMINV*GDGYPNYPDLIIIRCMF
VSKYHMYPINMYNYYVSIKIGNKLPPSFFSLFS
YLLSHHTRHTISVPVLSSKPLLMF*EIYLLFNIS
CTTVG*L*LTIMCSFK*LIAGRKLLNVSNIKK*
*VFEMMDMLITLI*SLHIICMEISLCTP*IWAI
IIC*LKK*KKDPPTV*
Sequence NM_175623
GGTTACCTGGCGGCGGGCGGGCGCGGCCGGGAGCGGAGGGCCGCGGTCGCGAAGAGGATGAAGAGAGAGTTCCCGAACAAGTCGGAAGCAGCTCACAACACCGGACGCCGCGCGGCAGGGCTGTGGACCTGGGGTGGTTTCGTGTCCCAGTCTTAGGAAACTACGCGCGAGGCACCGTGCTGAGGCGTAGAGGTCACCCT
CGGGAGGTTTCGGTGAAACCTGGTGGGAAATTCCGGGCAGGCGCCCGGAGTCGCGCCCAAGTAGGCAGCTCCGTGCCGCCAGACTTGTGTTCGGGGGAGT
TGAGACGAACTGCACGGGTGGGATTGCATGGCTCTGCCCTCCCAGCGTTGACAACTCGCCCCGACCGCCCAGGAAGCGCGAGCTTACTGGCTCCAGAAGT
GATGATGCTGGGTGGAAGTCGCAGCATGTGAAGAGTTGCCGGTTGTTATGGGATTAAAAAAGATGAAAGGGTTATCTTATGATGAGGCTTTTGCTATGGC
TAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTTGGTGTGTATGAATCAGGAACTCAAGAGCAGACTACC
TCACCAAGTGTCATCTACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTTCCTACACAACCCGTGT
ATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATT
AACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTT
GGGTTGAGTACTGATAGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAAGAACTCGCAAAAGCTC
AGAGGGAACTGAAGTTAAAAGATGAAGAATGTGAGAGGCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCTAGTCTATTTGA
GGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAACAGCTAAAAGAAGCACAAGGAAAAATTGATGTACTTCAAGCTGAA
GTAGCTGCATTGAAGACACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAGACACCTTTTAAAAAGGGGCATACAA
GAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGTCATCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGACTTATCCTTGTA
TAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTCTTAGACAAAATCTACCAGGAAGATATCTTTCCATGTTTAACATTC
TCAAAAAGTGAGTTGGCTTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTACAACCTATCCGGTTTGTGAAAGCTT
CTGCAGTTGAATGCGGAGGACCAAAAAAATGTGCTCTCACTGGCCAGAGTAAGTCCTGTAAACACAGAATTAAATTAGGGGACTCAAGCAACTATTATTA
TATTTCTCCTTTTTGCAGATACAGGATCACTTCTGTATGTAACTTTTTTACATACATTCGATACATTCAGCAGGGACTCGTGAAACAGCAGGATGTTGAT
CAGATGTTTTGGGAGGTTATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTCTGATGCTCTGCGTGGGACCATGCCT
GAACTCCCCGAATAACTGAAAAATGGCTGAATATTTTTATGGTTACTTGATATTTATTTCCAAGGAGTGAGCCTAAGACTTTTTTCCCCTTTTGCAAATT
GCTCTAAGAAGTACCATGATTTCTTTTAAACTGATCTATGCTGTGTTTGCTTATTCTTTAGTTGAACACACTATGAAGAATTCCAGGTGTACTAGTGAAT
GTAATTTATAGTTGCCAAAAAAAAAAAAAACCTGAAATAAATAAATGTTAGATTGAATGTGTGTACATTTTCTCTTCTAGCTCTGACATGGCATTTAGGG
TTAGCAGAATGTATTAAATAGTAATTTTCAAACTACACAGTAGCTTCCTTCCTTGTGAGAGGCAAGAAAGAAGTCTGAGTGGATAGTACTCACTTTCCAA
GGCCCCCACCTCTAGAATGGCTTTATTTTTATCTGTTTTCTATATTGGGTTTCAAAAAAGATTTTATTTGAAGAAATACTTCTGCTGCTACAAAGTTTGA
AAGTTACTATTTTAATTATTCTGCTCTCTGTAACTGAAAGAATCCCTTTATTTTGGTTATTCATTAAAATATAATAGAAGGCAGTCAGATTTTATCCCAG
AGATGTATTCCTGAGTGTCTTGATATAGTGTATTCATGTTTTATATGTGTTGACCACTATATTGTCATTGGAGGGACATAGATGTAAATGAGTTTGACGT
GTGTCAAAGGGGTTTAAAGGGGTGTGGATTGAATGAATGGTACGTGCGAAGTATATGCTGATTATAGAACCACTTGATCTCTGCATTCCAAATTGTAAAA
CTGACTCAACTGGAGAAATTATAACAAAGAGGTTTGTGGTAGACATGTAATAAGTATAGAAAAGCAAAAAGAAAAGAGAAACTGCTTTAGTTTCTGTTTA
GAGAAAGCTGCTGTTAATATTTTTGGATAGTAGCCTTTCAGCTTTCAGATATTTTCTACTTACATATGCATATTTTTGAAACAAAAAGTAGGCTTTTTTT
TTGCTTTTTAAACCTAAACATTAAATATATTTTCCCTTGGGTAAACCTACACATCCTAATCCCTGTTTATAGAATTTTAACATAATTTAATTGTGTTTGG
AGATGAGGTGGTTTTCAGTTTATTTTTCATATTATAATGCTGTGACGAGTATCCTTATCTGTACACTTCTGAACATTGTGGAGTTCTTTCATGTGGATGC
CTGGAGATAAAATTGTGTCGAGATATATATGTATTTTTAAATGTTTGATCTGCATTGCTAGATTGCCATCCAGAAAAGTTAATCAATTTGTATTCACAGC
AGCAGTGTACAAGAGGGCTGGTTTTCTGAAGATAACATTTTTTTCAGTCCTGTTCAGAGGTTTGGTCAATCTTACCTGTAGATGACTTCAGCCACCAGGC
TGGATGGGAGCCCACAGACAAAAGGACATTGGTGTATGTTATGGTGAAAACCATCAGTACCATGCCTAGCTCAAGAATGTGAAATTGAACCTGAAAAAAA
CTTTGAACCTACAATTTTATGTTCTGAAAATAGTTATTCTAATGTGAGGGCATTAATAAGAATATGTACCATCAAAGCTTCAGAAGATTTTCCGTACAAA
CTAAAATCACTTTTGGAGAAAGTACCTAAATAAAAAGAGAAACAAATCCAGGAGATACTGTACGGTTTGAAAGAAAGGTAATCAAATACTCAGAAAAAGT
TTGTTGATGACTTAAAAAGGATAAATAAAAAGTAAGACTAAAGAAAATCAGTATACCCATTAATAATAAATCTTTAGTAATCTATAAGGGGAAGAATGCT
TTTCAACCTTATACACTAGAAGCATGCTCTTTAAAATTAATGCAACAGGATGACGACTTGATGTAGAAACTATATGTGGAATTATAGATTAAAATGTGAT
TGAAACATATTTAGAAAATGTGATTATCTTCCTGATCCTACTCCCTTTAGGAAGAACTTCTTAAACTGGAAGCAGGAAAAAAAAAAACCATAAAAGATAA
CCATAAAAGAATATAAGTTATGGTATATTATAAATTCTTAATTTAGAAATCGTGCATCAGTAGTTAGGCATTGTGGCTCATGCCTGTAATCCCAGCACTT
TGGGAGGCAGAGGCAGAAGGATTACTTGAGCTGCTTGAGCCCAGGAGTTTGAGACGGGCCTGGGAAAAATAGGGAAACTCCATTTACACACACACACACA
CACACACACACACACACACTGTGTCCATGAACTTGGGAGGATGAGGTGGGAGGATTGCTTGAGCCCAGGGGTTCAAGTCCAACTTGGGCAACATAGGGAG
ACCTTGTCTCTAAAAAAAAAACTAAAGCTAAACTACAAACTGTGAGGCAATATCTGCAACATTTATAACTAGTAATAGCTTAGTATCAAGAATGTATGCA
GAAATTCTACAAACCAACAAAAAAGGACAGTGTCACAGAAAAACAGGCAAAAGACTGAACCAGGCCTTCCACACAATTAGAAGTGCATGTGGGCCAATAA
ACATTAAGAGGTTTTCATCTCTCAATCAGGAAAACGTAAATCAAGATGACAATGACATGTTCAAATTCATTCGATTGGTGAAAATGAAGAAACACAAAGT
CAAGTTTTGGAGAGGGTTTTAGTCATTAGGATCACTCACATATTGCTGATGGGGGTATCAATTGGTATATCCACTGTGAAAAACCATTCACTAGAAAAGT
TGGGCCAGGCCCAGTGGCTCATGCCTCTTGGCTTTGGGAGGCCAAGGTAGGAGGATCACTTGAGCCCAAGAGTTCAAGACCAGCTTGAGCAACATAGGGA
GACCACATCTGCACAAAAAGATTTTTTTGAATTAGCTGGGCATGGTGGTGCATGCCTGTGGTCCCAGCTACTTGGGAAGCTGAGGTGGAAGGATTGCTTA
AGCCCAGGAGGTTGAGGCTGCAGTGAATCATGATTGTGCCACTGCACTCTTACCTTGGGTGACAGAGTAAGATCATACCTTAAAAAAAAAAAAAAAGTAT
ACCCATGGGTCAGCAATTTCACTTTTCAGTATATACTTGAGAAATGCTTGCACAGGTCCCCCAGATCACACATATAAGAATGTTCTGGAATAAATTAAAA
TGTCTATTTTTAGGAAGGTGTAATGTGTTCACAGAATGGGTGATTATTACATGGCAGCAAAATGAATGAATACCAGCTACTTGCAGCACAATAACTCAGA
ATGAAAAAGCAATTCTGAGAAAACTATATGTGACATGATACTTTTCTTATAAAAGTCAAGAACAACTAAAACTGAACAGCTGTTTAGGCATTGACATATG
TGACAAAACTTTTAAAAAGTAATAAAGTTCAAGATAGTGGTTACCTCTGGAGAGGTAGAGGAGGAGCAAATCTATGAGTAAGTCACTGGTAATGTTTTAG
TCCCTGGGTTAGGTGGTGGGTTTTGGGGTGGTTCATTTGTCATTAAAAGTAAGTACATGAGCTGGGTGTAGTGGTGCGTGCTTATAGTCCCAGCTACTTG
GGAGTCTGAGATAGGAAGATCCTTGAGGCCAGTTCAAGGCTATAGTGTGCTATGATTTCACCTGTGAATAGCTACTATATTCCAACCTGGGCAACGTAGA
CCTTGCCCCCCTTTAAAAAAATTCAAAAACAAAATAAATGCATGGACAAATGAATAAGAGAGTTATGCATGGAACATCGGTGGTGTATTATGAATCAAGC
ATTATTACTAGCTCAGTTATATGTGCCTTCATTCCAAAACAAAAAATAAAAGGTAAGAAAATTGTTGAATTGCATTTGAGAGAGAGGAAAGGAAAGAATT
CAGGTCTGAATCTTAGGCTTTTGGCTTGAGCTATTGCAGTTTATTGAGATGGGGAAATACATGGTGGGGAAAGTTTGGGTATGTGCATAACAGAGACAGA
AATTCAGTGTTTGACAGATCAAGTGTGAGGTGCCCACTGAGCATCAAAGTGGATATGTTAAGCAGGTATTGGATGTACAAATCTAAATTCAGTAAGGTCA
GTCCAGGAGAAAATTTGGGGAGTAGTTAGCCATGGGATCAGATGGGCGCTTTAGGGACACTTTGGAGATGAAGTACAGCACTGAGCCCTGAGTTCCTGTG
ACAGAGAAGCAGCCTGCAAAGACGAAAGGAGGAGCTGTTAGGAAGAGCAAGGCAACAGAAAAGGAAGAACCAGCATGCTGATTATGTTCAGGAGAGTGTT
TCTACGCTGAATTTAATTGCCAAGATTACCAATTCTAAAGAAGAGGAGGACTCTTGGACAAGTTTTTAGAAGTTGGTTTGGAGCTGGGGTGAGAGCCTGG
CCTAATGGAGACAGCTCTGGATTGGGAGTCACTTAGACCTACATTCTGGTCTAGGTTTGGCTCCCAAAAACTGGGAAGGTTAGTTAGGTGGCCACTCCTC
TCTCTTCATGGTCTCTCTCAGCTTGAAGACAATTTACAGTCTTTGACTAAGCATCCACACTGGAAGAACAAGATTTGGTTTCTGAACATTGGGTCTTAGT
CCTTAAAATAACTTGCAACCTGTTACGTCTTCACTTACTCCCATCGCCACCACAAGAATCCTGTGTGTTTTTGTTTTGTGCATCCAGTCTAAAACGGGTC
TGCTTTTATTCATAGGCTTTTGTTTTCAGTGGTTTTTGTTGTTGCATTTTTCCCTAGATAAAATGTTTTTTCTATAAGACACTGCTTAAAAGAGTCCAAT
GCAGTATGAATTTGTATTTGTGTTTAACTTTTGTGCTTAACAGATCTGCCATGGCTGAACTCTCAGTTGCTTAAGCAAAATTCTGGGGCTTATTCTAGGT
TCCTTTATTTGTCATTGTCACTCCCATTCCAGTTATCAGCAAATTCCATCAGCTGTCTCCGAGACATCTTAAATCTGTCTACCTCCCTCCATGTCCACTG
CTACCACTCTGCCCAAGCTATTATCATCTTTCACCTGAACTCCTGCACTAATGTCTGCTGTCCTTGCATCCACTCCTGCCCTCCTACAATCACTGACGGC
AGCCGCAGGGATCTTTATAAAACGAAAATCAGATAATGTCACTTCCCTGCTTAAAGCCCTTTGAGTGGCTTCCCATTGCACTTAGAAAAAAAAAAAAAAA
AAAAAACTGGCCAGGTGCGATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCCCCTGAGGTTGGTAGTTCGAGACCTGCTTG
GCCAACATGGAGAAACCCTGTCTCTACTAAAAACACAAAATTAGTCAGGTGTGATGGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGTCAGGAG
AAACGCTCGAACCCAGGAGGCAGAGGTTGTGGTGAGTTGACATCACGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCGTCTGAAAAAAAAAA
AAAAAAACCCAAACTCAATAGAAAATCAAGTTTTCATAGTGGTAGTTGTTAACAGAGAAATAACAATGAAAGCTTTAAAAAACTCCATGAAAATTTGCAA
AACTTAAAAAAAAAATGTAGAAGAGGACTAAACTTGATAAAATATTAAAAGAATTGAAACCCTTCCTAAAGGCAGCTTCTCAAGGGAGCACAAGTTCACA
CACAGTTTACTTTTGGAGGAACGTCTGAGGTCATGAGGACTAGATTCTAGAGCTACAGGTCTCAGGGACAGTCTCGAGGGATACAGGGCCCCCATCACCA
CATCCCCAGATTTAACCGCAGCAGCTCAGCTTTTATCTGTATCTGTTGGAGCTCTCTAGGAAATGTCAATACCAAAGCAAACCCAAATCACAACTAGATT
AGATTACTATTCAAGAGAATGATTCTCTACCGAAACTCTGCAAAATGGGGATATCAAGAGAGTTGGAAAATGTAAGACGTAAAGACCATAATCAGGAAAA
TACGCATCATATTTGTTATTCACTGAGAGGGAGGAATTTCCACTTAAATCCTATTTCCAGCAGCTGGATTGTGCTCTCAGTGGAGTGCTCTGGATTCTGA
TTAATAGAGATTTTCTAGTCCTCCCAGCAACTTCCTTCTCAATTCTCTTCACTTTCCGCAGATCTCGGCACCAGGGTTGCATCTTGTGGGCTCCATTGTG
TTTTCACACAATGTGCTATTTGTCCTTCACAGTGTTTTGGTTTATTTTTCTGTTTGTCCATCTTGTTTTTGAACAATTGCCAGCATTTAAAAATGAGGAA
ATCTAAAATCTGCATTTCAAGCTGCTCTTTTTTAAAATGTGCCGTTTCGACAACACTGAGCCCACAGTCTTGAATGACAACACTTGGGTGGAGCTGAGTG
ACTCCACCTGTCGGGTGGCTACACCCTTGCTCAGGGTATGCACTCCATGGTTTGCTCTATGGCCCACCATCCTGGATTGTCTCCCTGACACCAAGGCTAA
GGGACCCACTTTACTCACTTATCTGCTGGGCCTTGGAAGTATTTCAGTTCGGAACCCCAATTCTAACCTTAGCTTCTCAGGCCATTAAATGAAATCTCAT
TTCTATGATGCTTCCTGTCACATCACTGTGCTGCTGAGAACATGAAGTCTGTGGGTGAATTGGTGGACGGGATCCAGAATCATTACTTGGCAGTGGATTA
TAGTGTGATGACTCATTTCCGGTGGTCTCCAGGAGACTTGGCTGGGAGCTTCTCTTGGAGTCTAGGGTTAGCCAGAGGCTACATGTTTTAGGCATCTTAA
TTCATATTTTATCTAAAGGCATATAAATCCTTAAAAAAAATCATTTGACTTCATCCTTGCTCCCTACATCCAGCCAGTAACCATTGCTTTGTTTTACATC
GCGTGCTTCAGGCTTTACTACAGCCTACCTGGATTTTGCAGTAGCTTCTTAAACTGCTTAAACTTTGGATATTGCCCCAGCCAACACATTCTGCCACAGA
GATCTCTCTGAGTTAAATGGGATTGTATCATGCCCCACACCCAAGCAGATAGAAACTGTCAATAGATACACTTAGAATGAATATGCATGGAATCAAATTA
CATTCAGAATCTACCACTATAGGTAGTGAATACAACAGGATAGCAGAGGCTGGGAAGGGTAATGGGGGTTGGGGGGTGGGAGGATAAAGGGGTTGGGTAA
TGGGTGTAAAAATCTATAGAAGGAATATGATCTGTTGTTTGGTAGCACAATAGGGTAAATACAGTTAATAATTTATTGTATATTTCACAATAAAGGAGTG
GATTTGGAATGTTCTCAACACAAATGATAAATGTTTGAGGTGATGGATACCCCAATTACCCTGATTTGATCATTATACGTTGTATGTTTGTATCAAAATA
TCATATGTACCCCATAAATATGTACAACTATTATGTATCCATAAAAATTGGAAATAAACTACCACCATCTTTCTTCAGCCTATTTTCCTATCTCCTCTCG
CACCATACTAGGCACACAATCTCTGTACCTGTGCTGTCTTCCAAGCCATTGCTCATGTTTTAAGAAATATACTTATTGTTTAATATATCCTGTACCACTG
TAGGATGACTGTAGTTAACAATAATGTGTAGTTTCAAATAGCTAATAGCTGGAAGGAAGTTGTTGAATGTTTCCAACATAAAGAAATGATAAGTGTTTGA
GATGATGGATATGCTAATTACCCTGATCTGATCACTACACATTATATGTATGGAAATATCATTGTGTACCCCATGAATATGGGCAATTATTATTTGTTAA
TTAAAAAAATAAAAAAAAGACCCACCCACTGTTTAA
- refseq_RAB3IP.F1 (forward primer)
- refseq_RAB3IP.R1 (reverse primer)
- Single exon skipping
Frame 0
GYLAAGGRGRERRAAVAKRMKREFPNKSEAAHNTGRRAAGLWTWGGFVSQS*ETTREAPC*GVEVTL
GRFR*NLVGNSGQAPGVAPK*AAPCRQTCVRGS
*DELHGWDCMALPSQR*QLAPTAQEARAYWLQK
**CWVEVAACEELPVVMGLKKMKGLSYDEAFAMA
NDPLEGFHEVNLASPTSPDLLGVYESGTQEQTT
SPSVIYRPHPSALSSVPIQANALDVSELPTQPV
YSSPRRLNCAEISSISFHVTDPAPCSTSGVTAGL
TKLTTRKDNYNAEREFLQGATITEACDGSDDIF
GLSTDSLSRLRSPSVLEVREKGYERLKEELAKA
QRELKLKDEECERLSKVRDQLGQELEELTASLFE
EAHKMVREANIKQATAEKQLKEAQGKIDVLQAE
VAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHT
RNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSLY
NEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLTF
SKSELASAVLEAVENNTLSIEPVGLQPIRFVKA
SAVECGGPKKCALTGQSKSCKHRIKLGDSSNYYY
ISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVD
QMFWEVMQLRKEMSLAKLGYFKEEL*CSAWDHA
*TPRITEKWLNIFMVT*YLFPRSEPKTFFPFCKL
L*EVP*FLLN*SMLCLLIL*LNTL*RIPGVLVN
VIYSCQKKKKPEINKC*IECVYIFSSSSDMAFR
VSRMY*IVIFKLHSSFLPCERQERSLSG*YSLSK
APTSRMALFLSVFYIGFQKRFYLKKYFCCYKV*
KLLF*LFCSL*LKESLYFGYSLKYNRRQSDFIP
EMYS*VS*YSVFMFYMC*PLYCHWRDIDVNEFDV
CQRGLKGCGLNEWYVRSIC*L*NHLISAFQIVK
LTQLEKL*QRGLW*TCNKYRKAKRKEKLL*FLF
RESCC*YFWIVAFQLSDIFYLHMHIFETKSRLFF
CFLNLNIKYIFPWVNLHILIPVYRILT*FNCVW
R*GGFQFIFHIIML*RVSLSVHF*TLWSSFMWM
PGDKIVSRYICIFKCLICIARLPSRKVNQFVFTA
AVYKRAGFLKITFFSVLFRGLVNLTCR*LQPPG
WMGAHRQKDIGVCYGENHQYHA*LKNVKLNLKK
TLNLQFYVLKIVILM*GH**EYVPSKLQKIFRTN
*NHFWRKYLNKKRNKSRRYCTV*KKGNQILRKS
LLMT*KG*IKSKTKENQYTH***IFSNL*GEEC
FSTLYTRSMLFKINATG*RLDVETICGIID*NVI
ETYLENVIIFLILLPLGRTS*TGSRKKKNHKR*
P*KNISYGIL*ILNLEIVHQ*LGIVAHACNPST
LGGRGRRIT*AA*AQEFETGLGKIGKLHLHTHTH
THTHTHCVHELGRMRWEDCLSPGVQVQLGQHRE
TLSLKKKLKLNYKL*GNICNIYN***LSIKNVC
RNSTNQQKRTVSQKNRQKTEPGLPHN*KCMWANK
H*EVFISQSGKRKSR*Q*HVQIHSIGENEETQS
QVLERVLVIRITHILLMGVSIGISTVKNHSLEK
LGQAQWLMPLGFGRPR*EDHLSPRVQDQLEQHRE
TTSAQKDFFELAGHGGACLWSQLLGKLRWKDCL
SPGG*GCSES*LCHCTLTLGDRVRSYLKKKKKV
YPWVSNFTFQYILEKCLHRSPRSHI*ECSGIN*N
VYF*EGVMCSQNG*LLHGSKMNEYQLLAAQ*LR
MKKQF*ENYM*HDTFLIKVKNN*N*TAV*ALTY
VTKLLKSNKVQDSGYLWRGRGGANL*VSHW*CFS
PWVRWWVLGWFICH*K*VHELGVVVRAYSPSYL
GV*DRKILEASSRL*CAMISPVNSYYIPTWAT*
TLPPFKKIQKQNKCMDK*IRELCMEHRWCIMNQA
LLLAQLYVPSFQNKK*KVRKLLNCI*ERGKERI
QV*ILGFWLELLQFIEMGKYMVGKVWVCA*QRQ
KFSV*QIKCEVPTEHQSGYVKQVLDVQI*IQ*GQ
SRRKFGE*LAMGSDGRFRDTLEMKYSTEP*VPV
TEKQPAKTKGGAVRKSKATEKEEPAC*LCSGEC
FYAEFNCQDYQF*RRGGLLDKFLEVGLELG*EPG
LMETALDWESLRPTFWSRFGSQKLGRLVRWPLL
SLHGLSQLEDNLQSLTKHPHWKNKIWFLNIGS*
SLK*LATCYVFTYSHRHHKNPVCFCFVHPV*NGS
AFIHRLLFSVVFVVAFFPR*NVFSIRHCLKESN
AV*ICICV*LLCLTDLPWLNSQLLKQNSGAYSR
FLYLSLSLPFQLSANSISCLRDILNLSTSLHVHC
YHSAQAIIIFHLNSCTNVCCPCIHSCPPTITDG
SRRDLYKTKIR*CHFPA*SPLSGFPLHLEKKKK
KKTGQVRWLMPVIPALWEAEAGGSPEVGSSRPAW
PTWRNPVSTKNTKLVRCDGACL*SQLLGRLSQE
KRSNPGGRGCGELTSRHCTPAWATRVKLRLKKK
KKNPNSIENQVFIVVVVNREITMKALKNSMKICK
T*KKNVEED*T**NIKRIETLPKGSFSREHKFT
HSLLLEERLRS*GLDSRATGLRDSLEGYRAPIT
TSPDLTAAAQLLSVSVGAL*EMSIPKQTQITTRL
DYYSRE*FSTETLQNGDIKRVGKCKT*RP*SGK
YASYLLFTEREEFPLKSYFQQLDCALSGVLWIL
INRDFLVLPATSFSILFTFRRSRHQGCILWAPLC
FHTMCYLSFTVFWFIFLFVHLVFEQLPAFKNEE
I*NLHFKLLFFKMCRFDNTEPTVLNDNTWVELS
DSTCRVATPLLRVCTPWFALWPTILDCLPDTKAK
GPTLLTYLLGLGSISVRNPNSNLSFSGH*MKSH
FYDASCHITVLLRT*SLWVNWWTGSRIITWQWI
IV**LISGGLQETWLGASLGV*G*PEATCFRHLN
SYFI*RHINP*KKSFDFILAPYIQPVTIALFYI
ACFRLYYSLPGFCSSFLNCLNFGYCPSQHILPQ
RSL*VKWDCIMPHTQADRNCQ*IHLE*ICMESNY
IQNLPL*VVNTTG*QRLGRVMGVGGWEDKGVG*
WV*KSIEGI*SVVW*HNRVNTVNNLLYISQ*RS
GFGMFSTQMINV*GDGYPNYPDLIIIRCMFVSKY
HMYPINMYNYYVSIKIGNKLPPSFFSLFSYLLS
HHTRHTISVPVLSSKPLLMF*EIYLLFNISCTT
VG*L*LTIMCSFK*LIAGRKLLNVSNIKK**VFE
MMDMLITLI*SLHIICMEISLCTP*IWAIIIC*
LKK*KKDPPTV*
Frame 1
VTWRRAGAAGSGGPRSRRG*RESSRTSRKQLTTPDAARQGCGPGVVSCPSLRKLRARHRAEA*RSP
SGGFGETWWEIPGRRPESRPSRQLRAARLVFGGV
ETNCTGGIAWLCPPSVDNSPRPPRKRELTGSRS
DDAGWKSQHVKSCRLLWD*KR*KGYLMMRLLLW
LMIPWKASMK*TLLHLLLRTFLVCMNQELKSRLP
HQVSSTGHTLQLYPLYLSRQMH*MFLNFLHNPC
IHPPDV*IVRKYLVSAFMLQTQPLALPLESQLD
*LN*LQERTTIMQRESFYRVLL*QRLAMAVMIFL
G*VLIVCLVYEAHLFWKLEKRAMND*KKNSQKL
RGN*S*KMKNVRGFQKCEINLDRNWKNSQLVYL
RKLIKW*EKQISSRQQQKNS*KKHKEKLMYFKLK
*LH*RHLYCPVLQHHLRRSLCQVERHLLKRGIQ
EIKAQAVL*VAVIRTSV*YSQL*KTAKRLTYPC
IMNSDCGRMSPQWTGRVLS*TKSTRKISFHV*HS
QKVSWLQLFWRLWKTIL*ALNQWDYNLSGL*KL
LQLNAEDQKNVLSLARVSPVNTELN*GTQATII
IFLLFADTGSLLYVTFLHTFDTFSRDS*NSRMLI
RCFGRLCS*EKRCHWQSWVISKRNSDALRGTMP
ELPE*LKNG*IFLWLLDIYFQGVSLRLFSPFAN
CSKKYHDFF*TDLCCVCLFFS*THYEEFQVY**M
*FIVAKKKKNLK*INVRLNVCTFSLLALTWHLG
LAECIK**FSNYTVASFLVRGKKEV*VDSTHFP
RPPPLEWLYFYLFSILGFKKDFI*RNTSAATKFE
SYYFNYSALCN*KNPFILVIH*NIIEGSQILSQ
RCIPECLDIVYSCFICVDHYIVIGGT*M*MSLT
CVKGV*RGVD*MNGTCEVYADYRTT*SLHSKL*N
*LNWRNYNKEVCGRHVISIEKQKEKRNCFSFCL
EKAAVNIFG**PFSFQIFSTYICIFLKQKVGFF
FAF*T*TLNIFSLG*TYTS*SLFIEF*HNLIVFG
DEVVFSLFFIL*CCDEYPYLYTSEHCGVLSCGC
LEIKLCRDIYVFLNV*SALLDCHPEKLINLYSQ
QQCTRGLVF*R*HFFQSCSEVWSILPVDDFSHQA
GWEPTDKRTLVYVMVKTISTMPSSRM*N*T*KK
L*TYNFMF*K*LF*CEGINKNMYHQSFRRFSVQ
TKITFGEST*IKRETNPGDTVRFERKVIKYSEKV
C**LKKDK*KVRLKKISIPINNKSLVIYKGKNA
FQPYTLEACSLKLMQQDDDLM*KLYVEL*IKM*
LKHI*KM*LSS*SYSL*EELLKLEAGKKKTIKDN
HKRI*VMVYYKFLI*KSCISS*ALWLMPVIPAL
WEAEAEGLLELLEPRSLRRAWEK*GNSIYTHTH
THTHTHTVSMNLGG*GGRIA*AQGFKSNLGNIGR
PCL*KKN*S*TTNCEAISATFITSNSLVSRMYA
EILQTNKKGQCHRKTGKRLNQAFHTIRSACGPI
NIKRFSSLNQENVNQDDNDMFKFIRLVKMKKHKV
KFWRGF*SLGSLTYC*WGYQLVYPL*KTIH*KS
WARPSGSCLLALGGQGRRIT*AQEFKTSLSNIG
RPHLHKKIFLN*LGMVVHACGPSYLGS*GGRIA*
AQEVEAAVNHDCATALLPWVTE*DHTLKKKKKY
THGSAISLFSIYLRNACTGPPDHTYKNVLE*IK
MSIFRKV*CVHRMGDYYMAAK*MNTSYLQHNNSE
*KSNSEKTICDMILFL*KSRTTKTEQLFRH*HM
*QNF*KVIKFKIVVTSGEVEEEQIYE*VTGNVL
VPGLGGGFWGGSFVIKSKYMSWV*WCVLIVPATW
ESEIGRSLRPVQGYSVL*FHL*IATIFQPGQRR
PCPPLKKFKNKINAWTNE*ESYAWNIGGVL*IK
HYY*LSYMCLHSKTKNKR*ENC*IAFEREERKEF
RSES*AFGLSYCSLLRWGNTWWGKFGYVHNRDR
NSVFDRSSVRCPLSIKVDMLSRYWMYKSKFSKV
SPGENLGSS*PWDQMGALGTLWR*STALSPEFL*
QRSSLQRRKEELLGRARQQKRKNQHADYVQESV
STLNLIAKITNSKEEEDSWTSF*KLVWSWGESL
A*WRQLWIGSHLDLHSGLGLAPKNWEG*LGGHSS
LFMVSLSLKTIYSL*LSIHTGRTRFGF*TLGLS
P*NNLQPVTSSLTPIATTRILCVFVLCIQSKTG
LLLFIGFCFQWFLLLHFSLDKMFFL*DTA*KSPM
QYEFVFVFNFCA*QICHG*TLSCLSKILGLILG
SFICHCHSHSSYQQIPSAVSETS*ICLPPSMST
ATTLPKLLSSFT*TPALMSAVLASTPALLQSLTA
AAGIFIKRKSDNVTSLLKAL*VASHCT*KKKKK
KKLARCDGSCL*SQHFGRPRRADPLRLVVRDLL
GQHGETLSLLKTQN*SGVMAHACNPSYLGG*VRR
NARTQEAEVVVS*HHAIALQPGQQE*NSV*KKK
KKTQTQ*KIKFS*W*LLTEK*Q*KL*KTP*KFA
KLKKKM*KRTKLDKILKELKPFLKAASQGSTSSH
TVYFWRNV*GHED*ILELQVSGTVSRDTGPPSP
HPQI*PQQLSFYLYLLELSRKCQYQSKPKSQLD
*ITIQENDSLPKLCKMGISRELENVRRKDHNQEN
THHICYSLRGRNFHLNPISSSWIVLSVECSGF*
LIEIF*SSQQLPSQFSSLSADLGTRVASCGLHC
VFTQCAICPSQCFGLFFCLSILFLNNCQHLKMRK
SKICISSCSFLKCAVSTTLSPQS*MTTLGWS*V
TPPVGWLHPCSGYALHGLLYGPPSWIVSLTPRL
RDPLYSLICWALEVFQFGTPILTLASQAIK*NLI
SMMLPVTSLCC*EHEVCG*IGGRDPESLLGSGL
*CDDSFPVVSRRLGWELLLESRVSQRLHVLGIL
IHILSKGI*ILKKNHLTSSLLPTSSQ*PLLCFTS
RASGFTTAYLDFAVAS*TA*TLDIAPANTFCHR
DLSELNGIVSCPTPKQIETVNRYT*NEYAWNQI
TFRIYHYR**IQQDSRGWEG*WGLGGGRIKGLGN
GCKNL*KEYDLLFGSTIG*IQLIIYCIFHNKGV
DLECSQHK**MFEVMDTPITLI*SLYVVCLYQN
IICTP*ICTTIMYP*KLEINYHHLSSAYFPISSR
TILGTQSLYLCCLPSHCSCFKKYTYCLIYPVPL
*DDCS*Q*CVVSNS**LEGSC*MFPT*RNDKCL
R*WIC*LP*SDHYTLYVWKYHCVPHEYGQLLFVN
*KNKKKTHPLF
Frame 2
LPGGGRARPGAEGRGREEDEERVPEQVGSSSQHRTPRGRAVDLGWFRVPVLGNYARGTVLRRRGHP
REVSVKPGGKFRAGARSRAQVGSSVPPDLCSGE
LRRTARVGLHGSALPALTTRPDRPGSASLLAPEV
MMLGGSRSM*RVAGCYGIKKDERVIL**GFCYG
**SLGRLP*SKPCFTYFSGPSWCV*IRNSRADY
LTKCHLPATPFSFILCTYPGKCIRCF*TSYTTRV
FIPQTFKLCGNI*YQLSCYRPSPLLYLWSHSWI
N*INYKKGQL*CRERVFTGCYYNRGLRWQ**YF
WVEY**SVSFTKPICFGS*RKGL*TIKRRTRKSS
EGTEVKR*RM*EAFKSARSTWTGIGRTHS*SI*
GSS*NGERSKYQAGNSRKTAKRSTRKN*CTSS*
SSCIEDTCIVQFSNITYAGAFARWKDTF*KGAYK
K*KHKQCYEWQSSGPQCDTANCKRLQRG*LILV
**IPIVEG*AHNGQDVSFLRQNLPGRYLSMFNI
LKK*VGFSCSGGCGKQYSKH*TSGITTYPVCESF
CS*MRRTKKMCSHWPE*VL*TQN*IRGLKQLLL
YFSFLQIQDHFCM*LFYIHSIHSAGTRETAGC*
SDVLGGYAVEKRDVIGKAGLFQRGTLMLCVGPCL
NSPNN*KMAEYFYGYLIFISKE*A*DFFPLLQI
ALRSTMISFKLIYAVFAYSLVEHTMKNSRCTSE
CNL*LPKKKKT*NK*MLD*MCVHFLF*L*HGI*G
*QNVLNSNFQTTQ*LPSL*EARKKSEWIVLTFQ
GPHL*NGFIFICFLYWVSKKILFEEILLLLQSL
KVTILIILLSVTERIPLFWLFIKI**KAVRFYPR
DVFLSVLI*CIHVLYVLTTILSLEGHRCK*V*R
VSKGFKGVWIE*MVRAKYMLIIEPLDLCIPNCK
TDSTGEIITKRFVVDM**V*KSKKKRETALVSV*
RKLLLIFLDSSLSAFRYFLLTYAYF*NKK*AFF
LLFKPKH*IYFPLGKPTHPNPCL*NFNII*LCL
EMRWFSVYFSYYNAVTSILICTLLNIVEFFHVDA
WR*NCVEIYMYF*MFDLHC*IAIQKS*SICIHS
SSVQEGWFSEDNIFFSPVQRFGQSYL*MTSATR
LDGSPQTKGHWCMLW*KPSVPCLAQECEIEPEKN
FEPTILCSENSYSNVRALIRICTIKASEDFPYK
LKSLLEKVPK*KEKQIQEILYGLKER*SNTQKK
FVDDLKRINKK*D*RKSVYPLIINL**SIRGRML
FNLIH*KHAL*N*CNRMTT*CRNYMWNYRLKCD
*NIFRKCDYLPDPTPFRKNFLNWKQEKKKP*KI
TIKEYKLWYIINS*FRNRASVVRHCGSCL*SQHF
GRQRQKDYLSCLSPGV*DGPGKNRETPFTHTHT
HTHTHTLCP*TWEDEVGGLLEPRGSSPTWAT*G
DLVSKKKTKAKLQTVRQYLQHL*LVIA*YQECMQ
KFYKPTKKDSVTEKQAKD*TRPSTQLEVHVGQ*
TLRGFHLSIRKT*IKMTMTCSNSFDW*K*RNTK
SSFGEGFSH*DHSHIADGGINWYIHCEKPFTRKV
GPGPVAHASWLWEAKVGGSLEPKSSRPA*AT*G
DHICTKRFF*ISWAWWCMPVVPATWEAEVEGLL
KPRRLRLQ*IMIVPLHSYLG*QSKIIP*KKKKSI
PMGQQFHFSVYT*EMLAQVPQITHIRMFWNKLK
CLFLGRCNVFTEWVIITWQQNE*IPATCSTITQ
NEKAILRKLYVT*YFSYKSQEQLKLNSCLGIDIC
DKTFKK**SSR*WLPLER*RRSKSMSKSLVMF*
SLG*VVGFGVVHLSLKVST*AGCSGACL*SQLL
GSLR*EDP*GQFKAIVCYDFTCE*LLYSNLGNVD
LAPL*KNSKTK*MHGQMNKRVMHGTSVVYYESS
IITSSVICAFIPKQKIKGKKIVELHLRERKGKN
SGLNLRLLA*AIAVY*DGEIHGGESLGMCITETE
IQCLTDQV*GAH*ASKWIC*AGIGCTNLNSVRS
VQEKIWGVVSHGIRWAL*GHFGDEVQH*ALSSC
DREAACKDERRSC*EEQGNRKGRTSMLIMFRRVF
LR*I*LPRLPILKKRRTLGQVFRSWFGAGVRAW
PNGDSSGLGVT*TYILV*VWLPKTGKVS*VATP
LSSWSLSA*RQFTVFD*ASTLEEQDLVSEHWVLV
LKITCNLLRLHLLPSPPQESCVFLFCASSLKRV
CFYS*AFVFSGFCCCIFP*IKCFFYKTLLKRVQ
CSMNLYLCLTFVLNRSAMAELSVA*AKFWGLF*V
PLFVIVTPIPVISKFHQLSPRHLKSVYLPPCPL
LPLCPSYYHLSPELLH*CLLSLHPLLPSYNH*R
QPQGSL*NENQIMSLPCLKPFEWLPIALRKKKKK
KNWPGAMAHACNPSTLGGRGGRIP*GW*FETCL
ANMEKPCLY*KHKISQV*WRMPVIPATWEAESG
ETLEPRRQRLW*VDITPLHSSLGNKSETPSEKKK
KKPKLNRKSSFHSGSC*QRNNNESFKKLHENLQ
NLKKKCRRGLNLIKY*KN*NPS*RQLLKGAQVH
TQFTFGGTSEVMRTRF*SYRSQGQSRGIQGPHHH
IPRFNRSSSAFICICWSSLGNVNTKANPNHN*I
RLLFKRMILYRNSAKWGYQESWKM*DVKTIIRK
IRIIFVIH*EGGIST*ILFPAAGLCSQWSALDSD
**RFSSPPSNFLLNSLHFPQISAPGLHLVGSIV
FSHNVLFVLHSVLVYFSVCPSCF*TIASI*K*G
NLKSAFQAALF*NVPFRQH*AHSLE*QHLGGAE*
LHLSGGYTLAQGMHSMVCSMAHHPGLSP*HQG*
GTHFTHLSAGPWKYFSSEPQF*P*LLRPLNEIS
FL*CFLSHHCAAENMKSVGELVDGIQNHYLAVDY
SVMTHFRWSPGDLAGSFSWSLGLARGYMF*AS*
FIFYLKAYKSLKKII*LHPCSLHPASNHCFVLH
RVLQALLQPTWILQ*LLKLLKLWILPQPTHSATE
ISLS*MGLYHAPHPSR*KLSIDTLRMNMHGIKL
HSESTTIGSEYNRIAEAGKGNGGWGVGG*RGWV
MGVKIYRRNMICCLVAQ*GKYS**FIVYFTIKEW
IWNVLNTNDKCLR*WIPQLP*FDHYTLYVCIKI
SYVPHKYVQLLCIHKNWK*TTTIFLQPIFLSPL
APY*AHNLCTCAVFQAIAHVLRNILIV*YILYHC
RMTVVNNNV*FQIANSWKEVVECFQHKEMISV*
DDGYANYPDLITTHYMYGNIIVYPMNMGNYYLL
IKKIKKRPTHCL
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