Sequence XM_001125090
CCTCGCTCCGCCTCCGGCCTCCTCCGAGAGCTCCAGACCTCCCGGCTACTCAGAAGCCCTCGGACTGCCCGGACCGCGCGATGGAGTCGACCGGCAGCGT
CGGGGAGGCCCCGGGCGGACCCCGGGTGCTGGTGGTGGGCGGCGGCATCGCGGGGCTGGGCGCGGCGCAGAGGCTCTGCGGCCACTCCGCCTTCCCGCAC
CTGCGGGTCCTGGAGGCCACGGCCCGCGCCGGGGGCCGCATCCGCTCGGAGCGCTGCTTCGGGGCTATCAAGGACTCACAAACTGCATGATGGCCGCCCT
GCCGGAGGACACTGTAGTTTTTGAGAAGCCTGTGAAGACCATCCACTGGAACGGGTCCTTCCAGGAGGCAGCCTTTCCCGGGGAGACCTTTCCAGTGTCG
GTAGAGTGTGAGGATGGAGACCGGTTCCCGGCGCACCATGTCATCGTCACCGTGCCCTTAGGTCTGTCCACGTTCTCTGTGGGTTCATTGCCGGACTTGA
GTCTGAGTTCATGGAGACTCTGTCGGATGAAGAAGTACTTCTGTGTCTCACCCAAGTGCTCCGGAGAGTGACAGCTCCAGATCCTGTTTGCGGGGGAAGC
CACACATCGCACGTTTTACTCCACGACGCACGGGGCTCTGCTGTCGGGATGGAGGGAGGCCGACCGCCTCCTCAGTCTGTGGGCCCCGCAGGTGCAGCAG
CCCAGGCCCAGGCTCTAGCTGGGCCCAGCCTACTCTGTTCCACCCGTGTCGGGGGTAGGCTGGGACCCTCATTTCTTCTGACAGATTTCAGTCTGGCTTG
AAATTTGGGGATGTTAATGAGGGTCCTCTGGTTTTTGGTAACCAGGGCCACCTTCTCAGTTCTTGTGTCTGTTATTGGAGTCTGGCCAGGGTTGACTTGA
GCTGAGACACCAGATGCTCACGGAGATGCTGGACACATAAAGCAAGTTACAGCCACA
- refseq_PAOX.F4 (forward primer)
- refseq_PAOX.R4 (reverse primer)
- Single exon skipping
Frame 0
PRSASGLLRELQTSRLLRSPRTARTARWSRPAA
SGRPRADPGCWWWAAASRGWARRRGSAATPPSRT
CGSWRPRPAPGAASARSAASGLSRTHKLHDGRP
AGGHCSF*EACEDHPLERVLPGGSLSRGDLSSV
GRV*GWRPVPGAPCHRHRALRSVHVLCGFIAGLE
SEFMETLSDEEVLLCLTQVLRRVTAPDPVCGGS
HTSHVLLHDARGSAVGMEGGRPPPQSVGPAGAA
AQAQALAGPSLLCSTRVGGRLGPSFLLTDFSLA*
NLGMLMRVLWFLVTRATFSVLVSVIGVWPGLT*
AETPDAHGDAGHIKQVTAT
Frame 1
LAPPPASSESSRPPGYSEALGLPGPRDGVDRQR
RGGPGRTPGAGGGRRHRGAGRGAEALRPLRLPA
PAGPGGHGPRRGPHPLGALLRGYQGLTNCMMAAL
PEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVS
VECEDGDRFPAHHVIVTVPLGLSTFSVGSLPDL
SLSSWRLCRMKKYFCVSPKCSGE*QLQILFAGEA
THRTFYSTTHGALLSGWREADRLLSLWAPQVQQ
PRPRL*LGPAYSVPPVSGVGWDPHFF*QISVWL
EIWGC**GSSGFW*PGPPSQFLCLLLESGQG*LE
LRHQMLTEMLDT*SKLQP
Frame 2
SLRLRPPPRAPDLPATQKPSDCPDRAMESTGSV
GEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPH
LRVLEATARAGGRIRSERCFGAIKDSQTA*WPP
CRRTL*FLRSL*RPSTGTGPSRRQPFPGRPFQCR
*SVRMETGSRRTMSSSPCP*VCPRSLWVHCRT*
V*VHGDSVG*RSTSVSHPSAPESDSSRSCLRGK
PHIARFTPRRTGLCCRDGGRPTASSVCGPRRCSS
PGPGSSWAQPTLFHPCRG*AGTLISSDRFQSGL
KFGDVNEGPLVFGNQGHLLSSCVCYWSLARVDL
S*DTRCSRRCWTHKASYSH
Sequence NM_207127
CCTCGCTCCGCCTCCGGCCTCCTCCGAGAGCTCCAGACCTCCCGGCTACTCAGAAGCCCTCGGACTGCCCGGACCGCGCGATGGAGTCGACCGGCAGCGT
CGGGGAGGCCCCGGGCGGACCCCGGGTGCTGGTGGTGGGCGGCGGCATCGCGGGGCTGGGCGCGGCGCAGAGGCTCTGCGGCCACTCCGCCTTCCCGCAC
CTGCGGGTCCTGGAGGCCACGGCCCGCGCCGGGGGCCGCATCCGCTCGGAGCGCTGCTTCGGTGGCGTGGTGGAGGTGGGCGCGCACTGGATCCATGGGC
CCTCCCGGGGTAACCCCGTCTTCCAGCTGGCTGCTGAGTACGGGCTGCTGGGGGAGAAGGAGCTGTCCCAGGAGAACCAGCTGGTGGAGACCGGGGGTCA
CGTGGGCCTGCCCTCCGTGAGCTACGCCAGCTCCGGGGCCAGCGTGAGCCTCCAGCTGGTGGCGGAGATGGCGACTCTGTTCTACGGCCTGATAGACCAG
ACCCGGGAGTTCCTGCACGCTGCAGAGACCCCGGTGCCCAGCGTCGGGGAGTACCTCAAGAAGGAGATTGGCCAGCACGTGGCCGGCTGGACAGAGGATG
AGGAGACCAGGAAGCTGAAGCTGGCCGTCCTGAACTCCTTCTTCAACCTGGAATGCTGTGTGAGCGGCACCCACAGCATGGACCTGGTGGCCCTGGCACC
CTTTGGGGAGTATACCGTGCTGCCGGGGCTGGACTGCACCTTTTCTAAGGGCTATCAAGGACTCACAAACTGCATGATGGCCGCCCTGCCGGAGGACACT
GTAGTTTTTGAGAAGCCTGTGAAGACCATCCACTGGAACGGGTCCTTCCAGGAGGCAGCCTTTCCCGGGGAGACCTTTCCAGTGTCGGTAGAGTGTGAGG
ATGGAGACCGGTTCCCGGCGCACCATGTCATCGTCACCGTGCCCTTAGGTCTGTCCACGTTCTCTGTGGGTTCATTGCCGGACTTGAGTCTGAGTTCATG
GAGACTCTGTCGGATGAAGAAGTACTTCTGTGTCTCACCCAAGTGCTCCGGAGAGTGACAGCTCCAGATCCTGTTTGCGGGGGAAGCCACACATCGCACG
TTTTACTCCACGACGCACGGGGCTCTGCTGTCGGGATGGAGGGAGGCCGACCGCCTCCTCAGTCTGTGGGCCCCGCAGGTGCAGCAGCCCAGGCCCAGGC
TCTAGCTGGGCCCAGCCTACTCTGTTCCACCCGTGTCGGGGGTAGGCTGGGACCCTCATTTCTTCTGACAGATTTCAGTCTGGCTTGAAATTTGGGGATG
TTAATGAGGGTCCTCTGGTTTTTGGTAACCAGGGCCACCTTCTCAGTTCTTGTGTCTGTTATTGGAGTCTGGCCAGGGTTGACTTGAGCTGAGACACCAG
ATGCTCACGGAGATGCTGGACACATAAAGCAAGTTACAGCCACA
- refseq_PAOX.F4 (forward primer)
- refseq_PAOX.R4 (reverse primer)
- Single exon skipping
Frame 0
PRSASGLLRELQTSRLLRSPRTARTARWSRPAA
SGRPRADPGCWWWAAASRGWARRRGSAATPPSRT
CGSWRPRPAPGAASARSAASVAWWRWARTGSMG
PPGVTPSSSWLLSTGCWGRRSCPRRTSWWRPGV
TWACPP*ATPAPGPA*ASSWWRRWRLCSTA**TR
PGSSCTLQRPRCPASGSTSRRRLASTWPAGQRM
RRPGS*SWPS*TPSSTWNAV*AAPTAWTWWPWH
PLGSIPCCRGWTAPFLRAIKDSQTA*WPPCRRTL
*FLRSL*RPSTGTGPSRRQPFPGRPFQCR*SVR
METGSRRTMSSSPCP*VCPRSLWVHCRT*V*VH
GDSVG*RSTSVSHPSAPESDSSRSCLRGKPHIAR
FTPRRTGLCCRDGGRPTASSVCGPRRCSSPGPG
SSWAQPTLFHPCRG*AGTLISSDRFQSGLKFGD
VNEGPLVFGNQGHLLSSCVCYWSLARVDLS*DTR
CSRRCWTHKASYSH
Frame 1
LAPPPASSESSRPPGYSEALGLPGPRDGVDRQR
RGGPGRTPGAGGGRRHRGAGRGAEALRPLRLPA
PAGPGGHGPRRGPHPLGALLRWRGGGGRALDPWA
LPG*PRLPAGC*VRAAGGEGAVPGEPAGGDRGS
RGPALRELRQLRGQREPPAGGGDGDSVLRPDRP
DPGVPARCRDPGAQRRGVPQEGDWPARGRLDRG*
GDQEAEAGRPELLLQPGMLCERHPQHGPGGPGT
LWGVYRAAGAGLHLF*GLSRTHKLHDGRPAGGH
CSF*EACEDHPLERVLPGGSLSRGDLSSVGRV*G
WRPVPGAPCHRHRALRSVHVLCGFIAGLESEFM
ETLSDEEVLLCLTQVLRRVTAPDPVCGGSHTSH
VLLHDARGSAVGMEGGRPPPQSVGPAGAAAQAQA
LAGPSLLCSTRVGGRLGPSFLLTDFSLA*NLGM
LMRVLWFLVTRATFSVLVSVIGVWPGLT*AETP
DAHGDAGHIKQVTAT
Frame 2
SLRLRPPPRAPDLPATQKPSDCPDRAMESTGSV
GEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPH
LRVLEATARAGGRIRSERCFGGVVEVGAHWIHG
PSRGNPVFQLAAEYGLLGEKELSQENQLVETGGH
VGLPSVSYASSGASVSLQLVAEMATLFYGLIDQ
TREFLHAAETPVPSVGEYLKKEIGQHVAGWTED
EETRKLKLAVLNSFFNLECCVSGTHSMDLVALAP
FGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECE
DGDRFPAHHVIVTVPLGLSTFSVGSLPDLSLSSW
RLCRMKKYFCVSPKCSGE*QLQILFAGEATHRT
FYSTTHGALLSGWREADRLLSLWAPQVQQPRPR
L*LGPAYSVPPVSGVGWDPHFF*QISVWLEIWGC
**GSSGFW*PGPPSQFLCLLLESGQG*LELRHQ
MLTEMLDT*SKLQP
Sequence XM_001125092
CCTCGCTCCGCCTCCGGCCTCCTCCGAGAGCTCCAGACCTCCCGGCTACTCAGAAGCCCTCGGACTGCCCGGACCGCGCGATGGAGTCGACCGGCAGCGT
CGGGGAGGCCCCGGGCGGACCCCGGGTGCTGGTGGTGGGCGGCGGCATCGCGGGGCTGGGCGCGGCGCAGAGGCTCTGCGGCCACTCCGCCTTCCCGCAC
CTGCGGGTCCTGGAGGCCACGGCCCGCGCCGGGGGCCGCATCCGCTCGGAGCGCTGCTTCGGGGCTATCAAGGACTCACAAACTGCATGATGGCCGCCCT
GCCGGAGGACACTGTAGTTTTTGAGAAGCCTGTGAAGACCATCCACTGGAACGGGTCCTTCCAGGAGGCAGCCTTTCCCGGGGAGACCTTTCCAGTGTCG
GTAGAGTGTGAGGATGGAGACCGGTTCCCGGCGCACCATGTCATCGTCACCGTGCCCTTAGGTCTGTCCACGTTCTCTGTGGGTTCATTGCCGGACTTGA
GTCTGAGTTCATGGAGACTCTGTCGGATGAAGAAGTACTTCTGTGTCTCACCCAAGTGCTCCGGAGAGTGACAGGAAACCCACGGCTCCCCGCGCCCAAG
AGCGTCCTGCGGTCTCGCTGGCACAGCGCCCCGTACACTAGGGGGTCCTACAGCTACGTGGCCGTGGGCAGTACTGGGGGCGACCTGGACCTGCTGGCTC
AGCCCCTCCCTGCAGACGGCGCCGGCGCCCAGCTCCAGATCCTGTTTGCGGGGGAAGCCACACATCGCACGTTTTACTCCACGACGCACGGGGCTCTGCT
GTCGGGATGGAGGGAGGCCGACCGCCTCCTCAGTCTGTGGGCCCCGCAGGTGCAGCAGCCCAGGCCCAGGCTCTAGCTGGGCCCAGCCTACTCTGTTCCA
CCCGTGTCGGGGGTAGGCTGGGACCCTCATTTCTTCTGACAGATTTCAGTCTGGCTTGAAATTTGGGGATGTTAATGAGGGTCCTCTGGTTTTTGGTAAC
CAGGGCCACCTTCTCAGTTCTTGTGTCTGTTATTGGAGTCTGGCCAGGGTTGACTTGAGCTGAGACACCAGATGCTCACGGAGATGCTGGACACATAAAG
CAAGTTACAGCCACA
- refseq_PAOX.F4 (forward primer)
- refseq_PAOX.R4 (reverse primer)
- Single exon skipping
Frame 0
PRSASGLLRELQTSRLLRSPRTARTARWSRPAA
SGRPRADPGCWWWAAASRGWARRRGSAATPPSRT
CGSWRPRPAPGAASARSAASGLSRTHKLHDGRP
AGGHCSF*EACEDHPLERVLPGGSLSRGDLSSV
GRV*GWRPVPGAPCHRHRALRSVHVLCGFIAGLE
SEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPK
SVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLA
QPLPADGAGAQLQILFAGEATHRTFYSTTHGALL
SGWREADRLLSLWAPQVQQPRPRL*LGPAYSVP
PVSGVGWDPHFF*QISVWLEIWGC**GSSGFW*
PGPPSQFLCLLLESGQG*LELRHQMLTEMLDT*S
KLQP
Frame 1
LAPPPASSESSRPPGYSEALGLPGPRDGVDRQR
RGGPGRTPGAGGGRRHRGAGRGAEALRPLRLPA
PAGPGGHGPRRGPHPLGALLRGYQGLTNCMMAAL
PEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVS
VECEDGDRFPAHHVIVTVPLGLSTFSVGSLPDL
SLSSWRLCRMKKYFCVSPKCSGE*QETHGSPRPR
ASCGLAGTAPRTLGGPTATWPWAVLGATWTCWL
SPSLQTAPAPSSRSCLRGKPHIARFTPRRTGLC
CRDGGRPTASSVCGPRRCSSPGPGSSWAQPTLFH
PCRG*AGTLISSDRFQSGLKFGDVNEGPLVFGN
QGHLLSSCVCYWSLARVDLS*DTRCSRRCWTHK
ASYSH
Frame 2
SLRLRPPPRAPDLPATQKPSDCPDRAMESTGSV
GEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPH
LRVLEATARAGGRIRSERCFGAIKDSQTA*WPP
CRRTL*FLRSL*RPSTGTGPSRRQPFPGRPFQCR
*SVRMETGSRRTMSSSPCP*VCPRSLWVHCRT*
V*VHGDSVG*RSTSVSHPSAPESDRKPTAPRAQ
ERPAVSLAQRPVH*GVLQLRGRGQYWGRPGPAGS
APPCRRRRRPAPDPVCGGSHTSHVLLHDARGSA
VGMEGGRPPPQSVGPAGAAAQAQALAGPSLLCS
TRVGGRLGPSFLLTDFSLA*NLGMLMRVLWFLVT
RATFSVLVSVIGVWPGLT*AETPDAHGDAGHIK
QVTAT
Sequence XM_001125088
CCTCGCTCCGCCTCCGGCCTCCTCCGAGAGCTCCAGACCTCCCGGCTACTCAGAAGCCCTCGGACTGCCCGGACCGCGCGATGGAGTCGACCGGCAGCGT
CGGGGAGGCCCCGGGCGGACCCCGGGTGCTGGTGGTGGGCGGCGGCATCGCGGGGCTGGGCGCGGCGCAGAGGCTCTGCGGCCACTCCGCCTTCCCGCAC
CTGCGGGTCCTGGAGGCCACGGCCCGCGCCGGGGGCCGCATCCGCTCGGAGCGCTGCTTCGGTGGCGTGGTGGAGGTGGGCGCGCACTGGATCCATGGGC
CCTCCCGGGGTAACCCCGTCTTCCAGCTGGCTGCTGAGTACGGGCTGCTGGGGGAGAAGGAGCTGTCCCAGGAGAACCAGCTGGTGGAGACCGGGGGTCA
CGTGGGCCTGCCCTCCGTGAGCTACGCCAGCTCCGGGGCCAGCGTGAGCCTCCAGCTGGTGGCGGAGATGGCGACTCTGTTCTACGGCCTGATAGACCAG
ACCCGGGAGTTCCTGCACGCTGCAGAGACCCCGGTGCCCAGCGTCGGGGAGTACCTCAAGAAGGAGATTGGCCAGCACGTGGCCGGCTGGACAGAGGATG
AGGAGACCAGGAAGCTGAAGCTGGCCGTCCTGAACTCCTTCTTCAACCTGGAATGCTGTGTGAGCGGCACCCACAGCATGGACCTGGTGGCCCTGGCACC
CTTTGGGGAGTATACCGTGCTGCCGGGGCTGGACTGCACCTTTTCTAAGGGCTATCAAGGACTCACAAACTGCATGATGGCCGCCCTGCCGGAGGACACT
GTAGTTTTTGAGAAGCCTGTGAAGACCATCCACTGGAACGGGTCCTTCCAGGAGGCAGCCTTTCCCGGGGAGACCTTTCCAGTGTCGGTAGAGTGTGAGG
ATGGAGACCGGTTCCCGGCGCACCATGTCATCGTCACCGTGCCCTTAGGTCTGTCCACGTTCTCTGTGGGTTCATTGCCGGACTTGAGTCTGAGTTCATG
GAGACTCTGTCGGATGAAGAAGTACTTCTGTGTCTCACCCAAGTGCTCCGGAGAGTGACAGGAAACCCACGGCTCCCCGCGCCCAAGAGCGTCCTGCGGT
CTCGCTGGCACAGCGCCCCGTACACTAGGGGGTCCTACAGCTACGTGGCCGTGGGCAGTACTGGGGGCGACCTGGACCTGCTGGCTCAGCCCCTCCCTGC
AGACGGCGCCGGCGCCCAGCTCCAGATCCTGTTTGCGGGGGAAGCCACACATCGCACGTTTTACTCCACGACGCACGGGGCTCTGCTGTCGGGATGGAGG
GAGGCCGACCGCCTCCTCAGTCTGTGGGCCCCGCAGGTGCAGCAGCCCAGGCCCAGGCTCTAGCTGGGCCCAGCCTACTCTGTTCCACCCGTGTCGGGGG
TAGGCTGGGACCCTCATTTCTTCTGACAGATTTCAGTCTGGCTTGAAATTTGGGGATGTTAATGAGGGTCCTCTGGTTTTTGGTAACCAGGGCCACCTTC
TCAGTTCTTGTGTCTGTTATTGGAGTCTGGCCAGGGTTGACTTGAGCTGAGACACCAGATGCTCACGGAGATGCTGGACACATAAAGCAAGTTACAGCCA
CA
- refseq_PAOX.F4 (forward primer)
- refseq_PAOX.R4 (reverse primer)
- Single exon skipping
Frame 0
PRSASGLLRELQTSRLLRSPRTARTARWSRPAA
SGRPRADPGCWWWAAASRGWARRRGSAATPPSRT
CGSWRPRPAPGAASARSAASVAWWRWARTGSMG
PPGVTPSSSWLLSTGCWGRRSCPRRTSWWRPGV
TWACPP*ATPAPGPA*ASSWWRRWRLCSTA**TR
PGSSCTLQRPRCPASGSTSRRRLASTWPAGQRM
RRPGS*SWPS*TPSSTWNAV*AAPTAWTWWPWH
PLGSIPCCRGWTAPFLRAIKDSQTA*WPPCRRTL
*FLRSL*RPSTGTGPSRRQPFPGRPFQCR*SVR
METGSRRTMSSSPCP*VCPRSLWVHCRT*V*VH
GDSVG*RSTSVSHPSAPESDRKPTAPRAQERPAV
SLAQRPVH*GVLQLRGRGQYWGRPGPAGSAPPC
RRRRRPAPDPVCGGSHTSHVLLHDARGSAVGME
GGRPPPQSVGPAGAAAQAQALAGPSLLCSTRVGG
RLGPSFLLTDFSLA*NLGMLMRVLWFLVTRATF
SVLVSVIGVWPGLT*AETPDAHGDAGHIKQVTA
T
Frame 1
LAPPPASSESSRPPGYSEALGLPGPRDGVDRQR
RGGPGRTPGAGGGRRHRGAGRGAEALRPLRLPA
PAGPGGHGPRRGPHPLGALLRWRGGGGRALDPWA
LPG*PRLPAGC*VRAAGGEGAVPGEPAGGDRGS
RGPALRELRQLRGQREPPAGGGDGDSVLRPDRP
DPGVPARCRDPGAQRRGVPQEGDWPARGRLDRG*
GDQEAEAGRPELLLQPGMLCERHPQHGPGGPGT
LWGVYRAAGAGLHLF*GLSRTHKLHDGRPAGGH
CSF*EACEDHPLERVLPGGSLSRGDLSSVGRV*G
WRPVPGAPCHRHRALRSVHVLCGFIAGLESEFM
ETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLR
SRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPA
DGAGAQLQILFAGEATHRTFYSTTHGALLSGWR
EADRLLSLWAPQVQQPRPRL*LGPAYSVPPVSG
VGWDPHFF*QISVWLEIWGC**GSSGFW*PGPPS
QFLCLLLESGQG*LELRHQMLTEMLDT*SKLQP
Frame 2
SLRLRPPPRAPDLPATQKPSDCPDRAMESTGSV
GEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPH
LRVLEATARAGGRIRSERCFGGVVEVGAHWIHG
PSRGNPVFQLAAEYGLLGEKELSQENQLVETGGH
VGLPSVSYASSGASVSLQLVAEMATLFYGLIDQ
TREFLHAAETPVPSVGEYLKKEIGQHVAGWTED
EETRKLKLAVLNSFFNLECCVSGTHSMDLVALAP
FGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECE
DGDRFPAHHVIVTVPLGLSTFSVGSLPDLSLSSW
RLCRMKKYFCVSPKCSGE*QETHGSPRPRASCG
LAGTAPRTLGGPTATWPWAVLGATWTCWLSPSL
QTAPAPSSRSCLRGKPHIARFTPRRTGLCCRDGG
RPTASSVCGPRRCSSPGPGSSWAQPTLFHPCRG
*AGTLISSDRFQSGLKFGDVNEGPLVFGNQGHL
LSSCVCYWSLARVDLS*DTRCSRRCWTHKASYSH
Sequence NM_207128
CCTCGCTCCGCCTCCGGCCTCCTCCGAGAGCTCCAGACCTCCCGGCTACTCAGAAGCCCTCGGACTGCCCGGACCGCGCGATGGAGTCGACCGGCAGCGT
CGGGGAGGCCCCGGGCGGACCCCGGGTGCTGGTGGTGGGCGGCGGCATCGCGGGGCTGGGCGCGGCGCAGAGGCTCTGCGGCCACTCCGCCTTCCCGCAC
CTGCGGGTCCTGGAGGCCACGGCCCGCGCCGGGGGCCGCATCCGCTCGGAGCGCTGCTTCGGTGGCGTGGTGGAGGTGGGCGCGCACTGGATCCATGGGC
CCTCCCGGGGTAACCCCGTCTTCCAGCTGGCTGCTGAGTACGGGCTGCTGGGGGAGAAGGAGCTGTCCCAGGAGAACCAGCTGGTGGAGACCGGGGGTCA
CGTGGGCCTGCCCTCCGTGAGCTACGCCAGCTCCGGGGCCAGCGTGAGCCTCCAGCTGGTGGCGGAGATGGCGACTCTGTTCTACGGCCTGATAGACCAG
ACCCGGGAGTTCCTGCACGCTGCAGAGACCCCGGTGCCCAGCGTCGGGGAGTACCTCAAGAAGGAGATTGGCCAGCACGTGGCCGGCTGGACAGAGGATG
AGGAGACCAGGAAGCTGAAGCTGGCCGTCCTGAACTCCTTCTTCAACCTGGAATGCTGTGTGAGCGGCACCCACAGCATGGACCTGGTGGCCCTGGCACC
CTTTGGGGAGTATACCGTGCTGCCGGGGCTGGACTGCACCTTTTCTAAGGGCTATCAAGGACTCACAAACTGCATGATGGCCGCCCTGCCGGAGGACACT
GTAGTTTTTGAGAAGCCTGTGAAGACCATCCACTGGAACGGGTCCTTCCAGGAGGCAGCCTTTCCCGGGGAGACCTTTCCAGTGTCGGTAGAGTGTGAGG
ATGGAGACCGGTTCCCGGCGCACCATGTCATCGTCACCGTGCCCTTAGGTTTTCTTAGGGAACATTTGGACACCTTCTTTGACCCTCCCCTGCCGGCTGA
GAAGGCAGAAGCAATCAGGAAGATAGGCTTTGGGACCAACAACAAAATCTTCCTGGAGTTTGAGGAGCCCTTCTGGGAGCCAGACTGCCAGCTGATCCAG
CTGGTGTGGGAGGACACGTCGCCCCTGGAGGATGCTGCCCCTGAGCTACAGGACGCCTGGTTCCGGAAGCTCATTGGCTTTGTGGTCCTGCCTGCCTTTG
CGTCTGTCCACGTTCTCTGTGGGTTCATTGCCGGACTTGAGTCTGAGTTCATGGAGACTCTGTCGGATGAAGAAGTACTTCTGTGTCTCACCCAAGTGCT
CCGGAGAGTGACAGCTCCAGATCCTGTTTGCGGGGGAAGCCACACATCGCACGTTTTACTCCACGACGCACGGGGCTCTGCTGTCGGGATGGAGGGAGGC
CGACCGCCTCCTCAGTCTGTGGGCCCCGCAGGTGCAGCAGCCCAGGCCCAGGCTCTAGCTGGGCCCAGCCTACTCTGTTCCACCCGTGTCGGGGGTAGGC
TGGGACCCTCATTTCTTCTGACAGATTTCAGTCTGGCTTGAAATTTGGGGATGTTAATGAGGGTCCTCTGGTTTTTGGTAACCAGGGCCACCTTCTCAGT
TCTTGTGTCTGTTATTGGAGTCTGGCCAGGGTTGACTTGAGCTGAGACACCAGATGCTCACGGAGATGCTGGACACATAAAGCAAGTTACAGCCACA
- refseq_PAOX.F4 (forward primer)
- refseq_PAOX.R4 (reverse primer)
- Single exon skipping
Frame 0
PRSASGLLRELQTSRLLRSPRTARTARWSRPAA
SGRPRADPGCWWWAAASRGWARRRGSAATPPSRT
CGSWRPRPAPGAASARSAASVAWWRWARTGSMG
PPGVTPSSSWLLSTGCWGRRSCPRRTSWWRPGV
TWACPP*ATPAPGPA*ASSWWRRWRLCSTA**TR
PGSSCTLQRPRCPASGSTSRRRLASTWPAGQRM
RRPGS*SWPS*TPSSTWNAV*AAPTAWTWWPWH
PLGSIPCCRGWTAPFLRAIKDSQTA*WPPCRRTL
*FLRSL*RPSTGTGPSRRQPFPGRPFQCR*SVR
METGSRRTMSSSPCP*VFLGNIWTPSLTLPCRL
RRQKQSGR*ALGPTTKSSWSLRSPSGSQTAS*SS
WCGRTRRPWRMLPLSYRTPGSGSSLALWSCLPL
RLSTFSVGSLPDLSLSSWRLCRMKKYFCVSPKC
SGE*QLQILFAGEATHRTFYSTTHGALLSGWREA
DRLLSLWAPQVQQPRPRL*LGPAYSVPPVSGVG
WDPHFF*QISVWLEIWGC**GSSGFW*PGPPSQ
FLCLLLESGQG*LELRHQMLTEMLDT*SKLQP
Frame 1
LAPPPASSESSRPPGYSEALGLPGPRDGVDRQR
RGGPGRTPGAGGGRRHRGAGRGAEALRPLRLPA
PAGPGGHGPRRGPHPLGALLRWRGGGGRALDPWA
LPG*PRLPAGC*VRAAGGEGAVPGEPAGGDRGS
RGPALRELRQLRGQREPPAGGGDGDSVLRPDRP
DPGVPARCRDPGAQRRGVPQEGDWPARGRLDRG*
GDQEAEAGRPELLLQPGMLCERHPQHGPGGPGT
LWGVYRAAGAGLHLF*GLSRTHKLHDGRPAGGH
CSF*EACEDHPLERVLPGGSLSRGDLSSVGRV*G
WRPVPGAPCHRHRALRFS*GTFGHLL*PSPAG*
EGRSNQEDRLWDQQQNLPGV*GALLGARLPADP
AGVGGHVAPGGCCP*ATGRLVPEAHWLCGPACLC
VCPRSLWVHCRT*V*VHGDSVG*RSTSVSHPSA
PESDSSRSCLRGKPHIARFTPRRTGLCCRDGGR
PTASSVCGPRRCSSPGPGSSWAQPTLFHPCRG*A
GTLISSDRFQSGLKFGDVNEGPLVFGNQGHLLS
SCVCYWSLARVDLS*DTRCSRRCWTHKASYSH
Frame 2
SLRLRPPPRAPDLPATQKPSDCPDRAMESTGSV
GEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPH
LRVLEATARAGGRIRSERCFGGVVEVGAHWIHG
PSRGNPVFQLAAEYGLLGEKELSQENQLVETGGH
VGLPSVSYASSGASVSLQLVAEMATLFYGLIDQ
TREFLHAAETPVPSVGEYLKKEIGQHVAGWTED
EETRKLKLAVLNSFFNLECCVSGTHSMDLVALAP
FGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECE
DGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAE
KAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQ
LVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAF
ASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVL
RRVTAPDPVCGGSHTSHVLLHDARGSAVGMEGG
RPPPQSVGPAGAAAQAQALAGPSLLCSTRVGGR
LGPSFLLTDFSLA*NLGMLMRVLWFLVTRATFSV
LVSVIGVWPGLT*AETPDAHGDAGHIKQVTAT
Sequence NM_152911
CCTCGCTCCGCCTCCGGCCTCCTCCGAGAGCTCCAGACCTCCCGGCTACTCAGAAGCCCTCGGACTGCCCGGACCGCGCGATGGAGTCGACCGGCAGCGT
CGGGGAGGCCCCGGGCGGACCCCGGGTGCTGGTGGTGGGCGGCGGCATCGCGGGGCTGGGCGCGGCGCAGAGGCTCTGCGGCCACTCCGCCTTCCCGCAC
CTGCGGGTCCTGGAGGCCACGGCCCGCGCCGGGGGCCGCATCCGCTCGGAGCGCTGCTTCGGTGGCGTGGTGGAGGTGGGCGCGCACTGGATCCATGGGC
CCTCCCGGGGTAACCCCGTCTTCCAGCTGGCTGCTGAGTACGGGCTGCTGGGGGAGAAGGAGCTGTCCCAGGAGAACCAGCTGGTGGAGACCGGGGGTCA
CGTGGGCCTGCCCTCCGTGAGCTACGCCAGCTCCGGGGCCAGCGTGAGCCTCCAGCTGGTGGCGGAGATGGCGACTCTGTTCTACGGCCTGATAGACCAG
ACCCGGGAGTTCCTGCACGCTGCAGAGACCCCGGTGCCCAGCGTCGGGGAGTACCTCAAGAAGGAGATTGGCCAGCACGTGGCCGGCTGGACAGAGGATG
AGGAGACCAGGAAGCTGAAGCTGGCCGTCCTGAACTCCTTCTTCAACCTGGAATGCTGTGTGAGCGGCACCCACAGCATGGACCTGGTGGCCCTGGCACC
CTTTGGGGAGTATACCGTGCTGCCGGGGCTGGACTGCACCTTTTCTAAGGGCTATCAAGGACTCACAAACTGCATGATGGCCGCCCTGCCGGAGGACACT
GTAGTTTTTGAGAAGCCTGTGAAGACCATCCACTGGAACGGGTCCTTCCAGGAGGCAGCCTTTCCCGGGGAGACCTTTCCAGTGTCGGTAGAGTGTGAGG
ATGGAGACCGGTTCCCGGCGCACCATGTCATCGTCACCGTGCCCTTAGGTTTTCTTAGGGAACATTTGGACACCTTCTTTGACCCTCCCCTGCCGGCTGA
GAAGGCAGAAGCAATCAGGAAGATAGGCTTTGGGACCAACAACAAAATCTTCCTGGAGTTTGAGGAGCCCTTCTGGGAGCCAGACTGCCAGCTGATCCAG
CTGGTGTGGGAGGACACGTCGCCCCTGGAGGATGCTGCCCCTGAGCTACAGGACGCCTGGTTCCGGAAGCTCATTGGCTTTGTGGTCCTGCCTGCCTTTG
CGTCTGTCCACGTTCTCTGTGGGTTCATTGCCGGACTTGAGTCTGAGTTCATGGAGACTCTGTCGGATGAAGAAGTACTTCTGTGTCTCACCCAAGTGCT
CCGGAGAGTGACAGGAAACCCACGGCTCCCCGCGCCCAAGAGCGTCCTGCGGTCTCGCTGGCACAGCGCCCCGTACACTAGGGGGTCCTACAGCTACGTG
GCCGTGGGCAGTACTGGGGGCGACCTGGACCTGCTGGCTCAGCCCCTCCCTGCAGACGGCGCCGGCGCCCAGCTCCAGATCCTGTTTGCGGGGGAAGCCA
CACATCGCACGTTTTACTCCACGACGCACGGGGCTCTGCTGTCGGGATGGAGGGAGGCCGACCGCCTCCTCAGTCTGTGGGCCCCGCAGGTGCAGCAGCC
CAGGCCCAGGCTCTAGCTGGGCCCAGCCTACTCTGTTCCACCCGTGTCGGGGGTAGGCTGGGACCCTCATTTCTTCTGACAGATTTCAGTCTGGCTTGAA
ATTTGGGGATGTTAATGAGGGTCCTCTGGTTTTTGGTAACCAGGGCCACCTTCTCAGTTCTTGTGTCTGTTATTGGAGTCTGGCCAGGGTTGACTTGAGC
TGAGACACCAGATGCTCACGGAGATGCTGGACACATAAAGCAAGTTACAGCCACA
- refseq_PAOX.F4 (forward primer)
- refseq_PAOX.R4 (reverse primer)
- Single exon skipping
Frame 0
PRSASGLLRELQTSRLLRSPRTARTARWSRPAA
SGRPRADPGCWWWAAASRGWARRRGSAATPPSRT
CGSWRPRPAPGAASARSAASVAWWRWARTGSMG
PPGVTPSSSWLLSTGCWGRRSCPRRTSWWRPGV
TWACPP*ATPAPGPA*ASSWWRRWRLCSTA**TR
PGSSCTLQRPRCPASGSTSRRRLASTWPAGQRM
RRPGS*SWPS*TPSSTWNAV*AAPTAWTWWPWH
PLGSIPCCRGWTAPFLRAIKDSQTA*WPPCRRTL
*FLRSL*RPSTGTGPSRRQPFPGRPFQCR*SVR
METGSRRTMSSSPCP*VFLGNIWTPSLTLPCRL
RRQKQSGR*ALGPTTKSSWSLRSPSGSQTAS*SS
WCGRTRRPWRMLPLSYRTPGSGSSLALWSCLPL
RLSTFSVGSLPDLSLSSWRLCRMKKYFCVSPKC
SGE*QETHGSPRPRASCGLAGTAPRTLGGPTATW
PWAVLGATWTCWLSPSLQTAPAPSSRSCLRGKP
HIARFTPRRTGLCCRDGGRPTASSVCGPRRCSS
PGPGSSWAQPTLFHPCRG*AGTLISSDRFQSGLK
FGDVNEGPLVFGNQGHLLSSCVCYWSLARVDLS
*DTRCSRRCWTHKASYSH
Frame 1
LAPPPASSESSRPPGYSEALGLPGPRDGVDRQR
RGGPGRTPGAGGGRRHRGAGRGAEALRPLRLPA
PAGPGGHGPRRGPHPLGALLRWRGGGGRALDPWA
LPG*PRLPAGC*VRAAGGEGAVPGEPAGGDRGS
RGPALRELRQLRGQREPPAGGGDGDSVLRPDRP
DPGVPARCRDPGAQRRGVPQEGDWPARGRLDRG*
GDQEAEAGRPELLLQPGMLCERHPQHGPGGPGT
LWGVYRAAGAGLHLF*GLSRTHKLHDGRPAGGH
CSF*EACEDHPLERVLPGGSLSRGDLSSVGRV*G
WRPVPGAPCHRHRALRFS*GTFGHLL*PSPAG*
EGRSNQEDRLWDQQQNLPGV*GALLGARLPADP
AGVGGHVAPGGCCP*ATGRLVPEAHWLCGPACLC
VCPRSLWVHCRT*V*VHGDSVG*RSTSVSHPSA
PESDRKPTAPRAQERPAVSLAQRPVH*GVLQLR
GRGQYWGRPGPAGSAPPCRRRRRPAPDPVCGGSH
TSHVLLHDARGSAVGMEGGRPPPQSVGPAGAAA
QAQALAGPSLLCSTRVGGRLGPSFLLTDFSLA*
NLGMLMRVLWFLVTRATFSVLVSVIGVWPGLT*A
ETPDAHGDAGHIKQVTAT
Frame 2
SLRLRPPPRAPDLPATQKPSDCPDRAMESTGSV
GEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPH
LRVLEATARAGGRIRSERCFGGVVEVGAHWIHG
PSRGNPVFQLAAEYGLLGEKELSQENQLVETGGH
VGLPSVSYASSGASVSLQLVAEMATLFYGLIDQ
TREFLHAAETPVPSVGEYLKKEIGQHVAGWTED
EETRKLKLAVLNSFFNLECCVSGTHSMDLVALAP
FGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDT
VVFEKPVKTIHWNGSFQEAAFPGETFPVSVECE
DGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAE
KAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQ
LVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAF
ASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVL
RRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYV
AVGSTGGDLDLLAQPLPADGAGAQLQILFAGEA
THRTFYSTTHGALLSGWREADRLLSLWAPQVQQP
RPRL*LGPAYSVPPVSGVGWDPHFF*QISVWLE
IWGC**GSSGFW*PGPPSQFLCLLLESGQG*LE
LRHQMLTEMLDT*SKLQP