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Sequences

Sequence NM_133178

ACTCGGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCG CCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTC CGGCAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAGTGCGAAT CCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGCGAGCCCATGTCATCTTC CAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCTGGGCGTCTACGTGCGCG TTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAA TGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCC CCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCCAGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCC TCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCG CGCCGAGCAGGACCTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATC GCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTG AGTACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATGAGATCAG CGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGAGCCCATGAGGGCCCCCAAAGGC CTGGCTTTTGCTGAGATCCAGGCCCGTCAGCTGACCCTGCAGTGGGAACCACTGGGCTACAACGTGACGCGTTGCCACACCTATACTGTGTCGCTGTGCT ATCACTACACCCTGGGCAGCAGCCACAACCAGACCATCCGAGAGTGTGTGAAGACAGAGCAAGGTGTCAGCCGCTACACCATCAAGAACCTGCTGCCCTA TCGGAACGTTCACGTGAGGCTTGTCCTCACTAACCCTGAGGGGCGCAAAGAGGGCAAGGAGGTCACTTTCCAGACGGATGAGGATGTGCCCAGTGGGATT GCAGCCGAGTCCCTGACCTTCACTCCACTGGAGGACATGATCTTCCTCAAGTGGGAGGAGCCCCAGGAGCCCAATGGTCTCATCACCCAGTATGAGATCA GCTACCAGAGCATCGAGTCATCAGACCCGGCAGTGAACGTGCCAGGCCCACGACGTACCATCTCCAAGCTCCGCAATGAGACCTACCATGTCTTCTCCAA CCTGCACCCAGGCACCACCTACCTGTTCTCCGTGCGGGCCCGCACAGGCAAAGGCTTCGGCCAGGCGGCACTCACTGAGATAACCACTAACATCTCTGCT CCCAGCTTTGATTATGCCGACATGCCGTCACCCCTGGGCGAGTCTGAGAACACCATCACCGTGCTGCTGAGGCCGGCACAGGGCCGCGGTGCGCCCATCA GTGTGTACCAGGTGATTGTGGAGGAGGAGCGGGCGCGGAGGCTGCGGCGGGAGCCAGGTGGACAGGACTGCTTCCCAGTGCCATTGACCTTCGAGGCGGC GCTGGCCCGAGGCCTGGTGCACTACTTCGGGGCCGAACTGGCGGCCAGCAGTCTACCTGAGGCCATGCCCTTTACCGTGGGTGACAACCAGACCTACCGA GGCTTCTGGAACCCACCACTTGAGCCTAGGAAGGCCTATCTCATCTACTTCCAGGCAGCAAGCCACCTGAAGGGGGAGACCCGGCTGAATTGCATCCGCA TTGCCAGGAAAGCTGCCTGCAAGGAAAGCAAGCGGCCCCTGGAGGTGTCCCAGAGATCGGAGGAGATGGGGCTTATCCTGGGCATCTGTGCAGGGGGGCT TGCTGTCCTCATCCTTCTCCTGGGTGCCATCATTGTCATCATCCGCAAAGGGAAGCCGGTGAACATGACCAAGGCCACCGTCAACTACCGCCAGGAGAAG ACACACATGATGAGCGCCGTGGACCGCAGCTTCACAGACCAGAGCACCCTGCAGGAGGACGAGCGGCTGGGCCTGTCCTTCATGGACACCCATGGCTACA GCACCCGGGGAGACCAGCGCAGCGGTGGGGTCACTGAGGCCAGCAGCCTCCTGGGGGGCTCCCCGAGGCGTCCCTGTGGCCGGAAGGGCTCCCCATACCA CACGGGGCAGCTGCACCCTGCGGTGCGTGTCGCAGACCTTCTGCAGCACATCAACCAGATGAAGACGGCCGAGGGTTACGGCTTCAAGCAGGAGTATGAG AGCTTCTTTGAAGGCTGGGACGCCACAAAGAAGAAAGACAAGGTCAAGGGCAGCCGGCAGGAGCCAATGCCTGCCTATGATCGGCACCGAGTGAAACTGC ACCCGATGCTGGGAGACCCCAATGCCGACTACATTAATGCCAACTACATAGATGGTTACCACAGGTCAAACCACTTCATAGCCACTCAAGGGCCGAAGCC TGAGATGGTCTATGACTTCTGGCGTATGGTGTGGCAGGAGCACTGTTCCAGCATCGTCATGATCACCAAGCTGGTCGAGGTGGGCAGGGTGAAATGCTCA CGGTACTGGCCGGAGGACTCAGACACCTACGGGGACATCAAGATTATGCTGGTGAAGACAGAGACCCTGGCTGAGTATGTCGTGCGCACTTTTGCCCTGG AGCGGAGAGGCTACTCTGCCCGGCACGAGGTCCGCCAGTTCCACTTCACAGCGTGGCCAGAGCATGGCGTCCCCTACCATGCCACGGGGCTGCTGGCTTT CATCCGGCGCGTGAAGGCCTCCACCCCACCTGATGCCGGGCCCATTGTCATCCACTGCAGCGCGGGCACCGGCCGCACAGGTTGCTATATCGTCCTGGAT GTGATGCTGGACATGGCAGAGTGTGAGGGCGTCGTGGACATTTACAACTGTGTGAAGACTCTCTGCTCCCGGCGTGTCAACATGATCCAGACTGAGGAGC AGTACATCTTCATTCATGATGCAATCCTGGAGGCCTGCCTGTGTGGGGAGACCACCATCCCTGTCAGTGAGTTCAAGGCCACCTACAAGGAGATGATCCG CATTGATCCTCAGAGTAATTCCTCCCAGCTGCGGGAAGAGTTCCAGACGCTGAACTCGGTCACCCCGCCGCTGGACGTGGAGGAGTGCAGCATCGCCCTG TTGCCCCGGAACCGCGACAAGAACCGCAGCATGGACGTCCTGCCGCCCGACCGCTGCCTGCCCTTCCTCATCTCCACTGATGGGGACTCCAACAACTACA TTAATGCAGCCCTGACTGACAGCTACACACGGAGTGCGGCCTTCATCGTGACCCTGCACCCGCTGCAGAGCACCACGCCCGACTTCTGGCGGCTGGTCTA CGATTACGGGTGCACCTCCATCGTCATGCTCAACCAGCTGAACCAGTCCAACTCCGCCTGGCCCTGCCTGCAGTACTGGCCAGAGCCAGGCCGGCAGCAA TATGGCCTCATGGAGGTGGAGTTTATGTCGGGCACAGCTGATGAAGACTTAGTGGCTCGAGTCTTCCGGGTGCAGAACATCTCTCGGTTGCAGGAGGGGC ACCTGCTGGTGCGGCACTTCCAGTTCCTGCGCTGGTCTGCATACCGGGACACACCTGACTCCAAGAAGGCCTTCTTGCACCTGCTGGCTGAGGTGGACAA GTGGCAGGCCGAGAGTGGGGATGGGCGCACCATCGTGCACTGCCTAAACGGGGGAGGACGCAGCGGCACCTTCTGCGCCTGCGCCACGGTCCTGGAGATG ATCCGCTGCCACAACTTGGTGGACGTTTTCTTTGCTGCCAAAACCCTCCGGAACTACAAACCCAACATGGTGGAGACCATGGATCAGTACCACTTTTGCT ACGATGTGGCCCTGGAGTACTTGGAGGGGCTGGAGTCAAGATAGCGGGGCCCTGGCCTGGGGCACCCACTGCACACTCAGGGCCAGACCCACCATCCTGG ACTGGCGAGGAAGATCAGTGCCTCCTGCTCTGCCCAAACACACTCCCATGGGGCAAGCACTGGAGTGGATGCTGGGCTATCTTGCTCCCCCTTCCACTGT GGGCAGGGCCTTTCGCTTGTCCCATGGGCGGGTGGTGGGCCAAGGAGGAGCTTAGCAAGTCTGCAGCCCAGCCCCACCTCCATAGGGTCCTGCAGGCCTG TGCTGAGAGGCCTGGTGCTGCCTGGCAGAGTGACAAAGGCTCAGGACGGCTGGCTCTGGGGGACTCAGGCCAAGCCCCTTGGCACCATCCTGGCTTTTGG CAGGGATGAGTGAGGCCCTGCAGAGAGCATCCCAGGCCAAGGTTCCCACTCAGCCTGCCCCCTCTGCATGTGGGTAGAGGATGTACTGGGACTTGGCATT TAGGATTCCATCTGGCCCAGCCCCTGAAGGTCCTGGGGAAGCAGGTCTCAATTCTGAATAGCCAGTGGGGCACACTGACTGTCCTCCCCAGGGGAACTGC AGCGCCCTCCTCCCCACTGCCCCCTGCAGCCCCTGAGATATTTTGCTCACTATCCCTCCCCACTTGCTTCCCTGATATGTGCTCTGAGCTTCCCTGAACC AGGATCTGCCTATTACTGCTGTGCCCCATGGGGGGCTCCTTCCCTGCCTGACCCACTGTTGCAGAATGAAGTCACCTCGCCCCCCTCTTCCTTTAATCTT CAGGCCTCACTGGCCTGTCCTGCTCAGCTTGGGCCAGTGACAATCTGCAAGGCTGAACAACAGCCCCTGGGGTTGAGGCCCCTGTGGCTCCTGGTCAGGC TGCCCGTTGTGGGGAGGGGCAGTGTTAGAGCAGGGCTGGTCATACCCTCTGGAGTTCAGAGGAAGAGGTAGGACCAGTGCTTTTTTGTTTCTTTTGTTAT TTTTGGTTGGGTGGGTGGGAAGGTCTCTTTAAAATGGGGCAGGCCACACCCCCATTCCGTGCCTCAATTTCCCCATCTGTAAACTGTAGATATGACTACT GACCTACCTCGCAGGGGGCTGTGGGGAGGCATAAGCTGATGTTTGTAAAGCGCTTTGTAAATAAACGTGCTCTCTGAATGCCA

refseq_PTPRU.F2 (forward primer)
refseq_PTPRU.R2 (reverse primer)
Single exon skipping

Frame 0

TRRQSRSAPRRSAPARAPARLGLGSGSGGGVPR AGPRDGRRRSNHGPCPGARAGTHLPALRAGDRDS GSWLHLRGGK*PSSALRVQPGPVR*LPVGASAN PPWHPGTCGPAPRLLLDGQHFPACPRPASPCHL PEPERE*YPLCAVQLLPVQPGRAQPGHPGRLRAR *WGPPGQCCVEYDWIPRPSVAPG*AGCQHFLAQ *ISGAV*GPHLPRPQGLHGPR*HPASQLPLRKG PTLLPPGRRGGQRGPERVVPVHGRGQSGRGRTLP LATAERGAGAGGGRAAHQPPALPGHFPAGCREP RRAGPVPLCVPGPARRGRL*LRGAHRQGAPNSH RAPTAAACWPHLPHHPAQHQLHHWRRADRAQGD* VPHGARALG*GARRQPADLQAVAPRPRHRV*DQ RAAHASRRRRHWPPWATPHQPHQMRRAHEGPQR PGFC*DPGPSADPAVGTTGLQRDALPHLYCVAVL SLHPGQQPQPDHPRVCEDRARCQPLHHQEPAAL SERSREACPH*P*GAQRGQGGHFPDG*GCAQWD CSRVPDLHSTGGHDLPQVGGAPGAQWSHHPV*DQ LPEHRVIRPGSERARPTTYHLQAPQ*DLPCLLQ PAPRHHLPVLRAGPHRQRLRPGGTH*DNH*HLC SQL*LCRHAVTPGRV*EHHHRAAEAGTGPRCAHQ CVPGDCGGGAGAEAAAGARWTGLLPSAIDLRGG AGPRPGALLRGRTGGQQST*GHALYRG*QPDLP RLLEPTT*A*EGLSHLLPGSKPPEGGDPAELHPH CQESCLQGKQAAPGGVPEIGGDGAYPGHLCRGA CCPHPSPGCHHCHHPQREAGEHDQGHRQLPPGE DTHDERRGPQLHRPEHPAGGRAAGPVLHGHPWLQ HPGRPAQRWGH*GQQPPGGLPEASLWPEGLPIP HGAAAPCGACRRPSAAHQPDEDGRGLRLQAGV* ELL*RLGRHKEERQGQGQPAGANACL*SAPSETA PDAGRPQCRLH*CQLHRWLPQVKPLHSHSRAEA *DGL*LLAYGVAGALFQHRHDHQAGRGGQGEML TVLAGGLRHLRGHQDYAGEDRDPG*VCRAHFCPG AERLLCPARGPPVPLHSVARAWRPLPCHGAAGF HPAREGLHPT*CRAHCHPLQRGHRPHRLLYRPG CDAGHGRV*GRRGHLQLCEDSLLPACQHDPD*GA VHLHS*CNPGGLPVWGDHHPCQ*VQGHLQGDDP H*SSE*FLPAAGRVPDAELGHPAAGRGGVQHRP VAPEPRQEPQHGRPAARPLPALPHLH*WGLQQLH *CSPD*QLHTECGLHRDPAPAAEHHARLLAAGL RLRVHLHRHAQPAEPVQLRLALPAVLARARPAA IWPHGGGVYVGHS**RLSGSSLPGAEHLSVAGGA PAGAALPVPALVCIPGHT*LQEGLLAPAG*GGQ VAGREWGWAHHRALPKRGRTQRHLLRLRHGPGD DPLPQLGGRFLCCQNPPELQTQHGGDHGSVPLLL RCGPGVLGGAGVKIAGPWPGAPTAHSGPDPPSW TGEEDQCLLLCPNTLPWGKHWSGCWAILLPLPL WAGPFACPMGGWWAKEELSKSAAQPHLHRVLQAC AERPGAAWQSDKGSGRLALGDSGQAPWHHPGFW QG*VRPCREHPRPRFPLSLPPLHVGRGCTGTWH LGFHLAQPLKVLGKQVSILNSQWGTLTVLPRGTA APSSPLPPAAPEIFCSLSLPTCFPDMCSELP*T RICLLLLCPMGGSFPA*PTVAE*SHLAPLFL*S SGLTGLSCSAWASDNLQG*TTAPGVEAPVAPGQA ARCGEGQC*SRAGHTLWSSEEEVGPVLFCFFCY FWLGGWEGLFKMGQATPPFRASISPSVNCRYDY *PTSQGAVGRHKLMFVKRFVNKRAL*MP

Frame 1

LGASPAPRRAAPLRLGLRLASGWARAPGAASPA PGPGTGGDAPTMARAQALVLALTFQLCAPETET PAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRI HPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIF QSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVR VNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPN EYQVLFEALISPDRRGYMGLDDILLLSYPCAKA PHFSRLGDVEVNAGQNASFQCMAAGRAAEAERF LLQRQSGALVPAAGVRHISHRRFLATFPLAAVSR AEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPI APPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEI EYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEIS VLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKG LAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLC YHYTLGSSHNQTIRECVKTEQGVSRYTIKNLLPY RNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGI AAESLTFTPLEDMIFLKWEEPQEPNGLITQYEI SYQSIESSDPAVNVPGPRRTISKLRNETYHVFSN LHPGTTYLFSVRARTGKGFGQAALTEITTNISA PSFDYADMPSPLGESENTITVLLRPAQGRGAPI SVYQVIVEEERARRLRREPGGQDCFPVPLTFEAA LARGLVHYFGAELAASSLPEAMPFTVGDNQTYR GFWNPPLEPRKAYLIYFQAASHLKGETRLNCIR IARKAACKESKRPLEVSQRSEEMGLILGICAGGL AVLILLLGAIIVIIRKGKPVNMTKATVNYRQEK THMMSAVDRSFTDQSTLQEDERLGLSFMDTHGY STRGDQRSGGVTEASSLLGGSPRRPCGRKGSPYH TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYE SFFEGWDATKKKDKVKGSRQEPMPAYDRHRVKL HPMLGDPNADYINANYIDGYHRSNHFIATQGPKP EMVYDFWRMVWQEHCSSIVMITKLVEVGRVKCS RYWPEDSDTYGDIKIMLVKTETLAEYVVRTFAL ERRGYSARHEVRQFHFTAWPEHGVPYHATGLLAF IRRVKASTPPDAGPIVIHCSAGTGRTGCYIVLD VMLDMAECEGVVDIYNCVKTLCSRRVNMIQTEE QYIFIHDAILEACLCGETTIPVSEFKATYKEMIR IDPQSNSSQLREEFQTLNSVTPPLDVEECSIAL LPRNRDKNRSMDVLPPDRCLPFLISTDGDSNNY INAALTDSYTRSAAFIVTLHPLQSTTPDFWRLVY DYGCTSIVMLNQLNQSNSAWPCLQYWPEPGRQQ YGLMEVEFMSGTADEDLVARVFRVQNISRLQEG HLLVRHFQFLRWSAYRDTPDSKKAFLHLLAEVDK WQAESGDGRTIVHCLNGGGRSGTFCACATVLEM IRCHNLVDVFFAAKTLRNYKPNMVETMDQYHFC YDVALEYLEGLESR*RGPGLGHPLHTQGQTHHPG LARKISASCSAQTHSHGASTGVDAGLSCSPFHC GQGLSLVPWAGGGPRRSLASLQPSPTSIGSCRP VLRGLVLPGRVTKAQDGWLWGTQAKPLGTILAFG RDE*GPAESIPGQGSHSACPLCMWVEDVLGLGI *DSIWPSP*RSWGSRSQF*IASGAH*LSSPGEL QRPPPHCPLQPLRYFAHYPSPLASLICALSFPEP GSAYYCCAPWGAPSLPDPLLQNEVTSPPSSFNL QASLACPAQLGPVTICKAEQQPLGLRPLWLLVR LPVVGRGSVRAGLVIPSGVQRKR*DQCFFVSFVI FGWVGGKVSLKWGRPHPHSVPQFPHL*TVDMTT DLPRRGLWGGIS*CL*SAL*INVLSEC

Frame 2

SAPVPLRAAPLRSGSGSGSPRAGLGLRGRRPPR RAPGRAATLQPWPVPRRSCWHSPSSSARRRPRL RQLAAPSRRQVTQQCPASTARPSTMTSSGSKCE STLAPGHLRTCPTAPT*WSTLPSMPQASEPMSSS RA*ARMIPTVCSSATSCTAGTGTARAPWASTCA LMGAPWAVLCGI*LDPTAVSGTRLSWLSALSGP MNIRCCLRPSSPQTAGATWA*MTSCFSATPAQRP HTSPAWATWRSTRARTRRSSAWPRAERPRPNAS SCNGRAGRWCRRRACGTSATGASWPLSRWLP*A APSRTCTAVCPRPRAARASLTSRSSSSRSPQLPS RPHSCCVLAPPTSSSSSTPTPSLATGRSCARRL STAWRAGPGLRCTPSACRPTSCGTSTPTQSMRS ACCSRVPETAALAALGHPSSAAPNAQSP*GPPKA WLLLRSRPVS*PCSGNHWATT*RVATPILCRCA ITTPWAAATTRPSESV*RQSKVSAATPSRTCCP IGTFT*GLSSLTLRGAKRARRSLSRRMRMCPVGL QPSP*PSLHWRT*SSSSGRSPRSPMVSSPSMRS ATRASSHQTRQ*TCQAHDVPSPSSAMRPTMSSP TCTQAPPTCSPCGPAQAKASARRHSLR*PLTSLL PALIMPTCRHPWASLRTPSPCC*GRHRAAVRPS VCTR*LWRRSGRGGCGGSQVDRTASQCH*PSRR RWPEAWCTTSGPNWRPAVYLRPCPLPWVTTRPTE ASGTHHLSLGRPISSTSRQQAT*RGRPG*IASA LPGKLPARKASGPWRCPRDRRRWGLSWASVQGG LLSSSFSWVPSLSSSAKGSR*T*PRPPSTTARRR HT**APWTAASQTRAPCRRTSGWACPSWTPMAT APGETSAAVGSLRPAASWGAPRGVPVAGRAPHT TRGSCTLRCVSQTFCSTSTR*RRPRVTASSRSMR ASLKAGTPQRRKTRSRAAGRSQCLPMIGTE*NC TRCWETPMPTTLMPTT*MVTTGQTTS*PLKGRS LRWSMTSGVWCGRSTVPASS*SPSWSRWAG*NAH GTGRRTQTPTGTSRLCW*RQRPWLSMSCALLPW SGEATLPGTRSASSTSQRGQSMASPTMPRGCWL SSGA*RPPPHLMPGPLSSTAARAPAAQVAISSWM *CWTWQSVRASWTFTTV*RLSAPGVST*SRLRS STSSFMMQSWRPACVGRPPSLSVSSRPPTRR*S ALILRVIPPSCGKSSRR*TRSPRRWTWRSAASPC CPGTATRTAAWTSCRPTAACPSSSPLMGTPTTT LMQP*LTATHGVRPSS*PCTRCRAPRPTSGGWS TITGAPPSSCSTS*TSPTPPGPACSTGQSQAGSN MASWRWSLCRAQLMKT*WLESSGCRTSLGCRRG TCWCGTSSSCAGLHTGTHLTPRRPSCTCWLRWT SGRPRVGMGAPSCTA*TGEDAAAPSAPAPRSWR* SAATTWWTFSLLPKPSGTTNPTWWRPWISTTFA TMWPWSTWRGWSQDSGALAWGTHCTLRARPTIL DWRGRSVPPALPKHTPMGQALEWMLGYLAPPSTV GRAFRLSHGRVVGQGGA*QVCSPAPPP*GPAGL C*EAWCCLAE*QRLRTAGSGGLRPSPLAPSWLL AGMSEALQRASQAKVPTQPAPSACG*RMYWDLAF RIPSGPAPEGPGEAGLNSE*PVGHTDCPPQGNC SALLPTAPCSP*DILLTIPPHLLP*YVL*ASLN QDLPITAVPHGGLLPCLTHCCRMKSPRPPLPLIF RPHWPVLLSLGQ*QSARLNNSPWG*GPCGSWSG CPLWGGAVLEQGWSYPLEFRGRGRTSAFLFLLL FLVGWVGRSL*NGAGHTPIPCLNFPICKL*I*LL TYLAGGCGEA*ADVCKALCK*TCSLNA

Sequence NM_005704

ACTCGGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCG CCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTC CGGCAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAGTGCGAAT CCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGCGAGCCCATGTCATCTTC CAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCTGGGCGTCTACGTGCGCG TTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAA TGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCC CCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCCAGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCC TCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCG CGCCGAGCAGGACCTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATC GCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTG AGTACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATGAGATCAG CGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGAGCCCATGAGGGCCCCCAAAGGC CTGGCTTTTGCTGAGATCCAGGCCCGTCAGCTGACCCTGCAGTGGGAACCACTGGGCTACAACGTGACGCGTTGCCACACCTATACTGTGTCGCTGTGCT ATCACTACACCCTGGGCAGCAGCCACAACCAGACCATCCGAGAGTGTGTGAAGACAGAGCAAGGTGTCAGCCGCTACACCATCAAGAACCTGCTGCCCTA TCGGAACGTTCACGTGAGGCTTGTCCTCACTAACCCTGAGGGGCGCAAAGAGGGCAAGGAGGTCACTTTCCAGACGGATGAGGATGTGCCCAGTGGGATT GCAGCCGAGTCCCTGACCTTCACTCCACTGGAGGACATGATCTTCCTCAAGTGGGAGGAGCCCCAGGAGCCCAATGGTCTCATCACCCAGTATGAGATCA GCTACCAGAGCATCGAGTCATCAGACCCGGCAGTGAACGTGCCAGGCCCACGACGTACCATCTCCAAGCTCCGCAATGAGACCTACCATGTCTTCTCCAA CCTGCACCCAGGCACCACCTACCTGTTCTCCGTGCGGGCCCGCACAGGCAAAGGCTTCGGCCAGGCGGCACTCACTGAGATAACCACTAACATCTCTGCT CCCAGCTTTGATTATGCCGACATGCCGTCACCCCTGGGCGAGTCTGAGAACACCATCACCGTGCTGCTGAGGCCGGCACAGGGCCGCGGTGCGCCCATCA GTGTGTACCAGGTGATTGTGGAGGAGGAGCGGGCGCGGAGGCTGCGGCGGGAGCCAGGTGGACAGGACTGCTTCCCAGTGCCATTGACCTTCGAGGCGGC GCTGGCCCGAGGCCTGGTGCACTACTTCGGGGCCGAACTGGCGGCCAGCAGTCTACCTGAGGCCATGCCCTTTACCGTGGGTGACAACCAGACCTACCGA GGCTTCTGGAACCCACCACTTGAGCCTAGGAAGGCCTATCTCATCTACTTCCAGGCAGCAAGCCACCTGAAGGGGGAGACCCGGCTGAATTGCATCCGCA TTGCCAGGAAAGCTGCCTGCAAGGAAAGCAAGCGGCCCCTGGAGGTGTCCCAGAGATCGGAGGAGATGGGGCTTATCCTGGGCATCTGTGCAGGGGGGCT TGCTGTCCTCATCCTTCTCCTGGGTGCCATCATTGTCATCATCCGCAAAGGGAGAGACCACTATGCCTACTCCTACTACCCGAAGCCGGTGAACATGACC AAGGCCACCGTCAACTACCGCCAGGAGAAGACACACATGATGAGCGCCGTGGACCGCAGCTTCACAGACCAGAGCACCCTGCAGGAGGACGAGCGGCTGG GCCTGTCCTTCATGGACACCCATGGCTACAGCACCCGGGGAGACCAGCGCAGCGGTGGGGTCACTGAGGCCAGCAGCCTCCTGGGGGGCTCCCCGAGGCG TCCCTGTGGCCGGAAGGGCTCCCCATACCACACGGGGCAGCTGCACCCTGCGGTGCGTGTCGCAGACCTTCTGCAGCACATCAACCAGATGAAGACGGCC GAGGGTTACGGCTTCAAGCAGGAGTATGAGAGCTTCTTTGAAGGCTGGGACGCCACAAAGAAGAAAGACAAGGTCAAGGGCAGCCGGCAGGAGCCAATGC CTGCCTATGATCGGCACCGAGTGAAACTGCACCCGATGCTGGGAGACCCCAATGCCGACTACATTAATGCCAACTACATAGATGGTTACCACAGGTCAAA CCACTTCATAGCCACTCAAGGGCCGAAGCCTGAGATGGTCTATGACTTCTGGCGTATGGTGTGGCAGGAGCACTGTTCCAGCATCGTCATGATCACCAAG CTGGTCGAGGTGGGCAGGGTGAAATGCTCACGGTACTGGCCGGAGGACTCAGACACCTACGGGGACATCAAGATTATGCTGGTGAAGACAGAGACCCTGG CTGAGTATGTCGTGCGCACTTTTGCCCTGGAGCGGAGAGGCTACTCTGCCCGGCACGAGGTCCGCCAGTTCCACTTCACAGCGTGGCCAGAGCATGGCGT CCCCTACCATGCCACGGGGCTGCTGGCTTTCATCCGGCGCGTGAAGGCCTCCACCCCACCTGATGCCGGGCCCATTGTCATCCACTGCAGCGCGGGCACC GGCCGCACAGGTTGCTATATCGTCCTGGATGTGATGCTGGACATGGCAGAGTGTGAGGGCGTCGTGGACATTTACAACTGTGTGAAGACTCTCTGCTCCC GGCGTGTCAACATGATCCAGACTGAGGAGCAGTACATCTTCATTCATGATGCAATCCTGGAGGCCTGCCTGTGTGGGGAGACCACCATCCCTGTCAGTGA GTTCAAGGCCACCTACAAGGAGATGATCCGCATTGATCCTCAGAGTAATTCCTCCCAGCTGCGGGAAGAGTTCCAGACGCTGAACTCGGTCACCCCGCCG CTGGACGTGGAGGAGTGCAGCATCGCCCTGTTGCCCCGGAACCGCGACAAGAACCGCAGCATGGACGTCCTGCCGCCCGACCGCTGCCTGCCCTTCCTCA TCTCCACTGATGGGGACTCCAACAACTACATTAATGCAGCCCTGACTGACAGCTACACACGGAGTGCGGCCTTCATCGTGACCCTGCACCCGCTGCAGAG CACCACGCCCGACTTCTGGCGGCTGGTCTACGATTACGGGTGCACCTCCATCGTCATGCTCAACCAGCTGAACCAGTCCAACTCCGCCTGGCCCTGCCTG CAGTACTGGCCAGAGCCAGGCCGGCAGCAATATGGCCTCATGGAGGTGGAGTTTATGTCGGGCACAGCTGATGAAGACTTAGTGGCTCGAGTCTTCCGGG TGCAGAACATCTCTCGGTTGCAGGAGGGGCACCTGCTGGTGCGGCACTTCCAGTTCCTGCGCTGGTCTGCATACCGGGACACACCTGACTCCAAGAAGGC CTTCTTGCACCTGCTGGCTGAGGTGGACAAGTGGCAGGCCGAGAGTGGGGATGGGCGCACCATCGTGCACTGCCTAAACGGGGGAGGACGCAGCGGCACC TTCTGCGCCTGCGCCACGGTCCTGGAGATGATCCGCTGCCACAACTTGGTGGACGTTTTCTTTGCTGCCAAAACCCTCCGGAACTACAAACCCAACATGG TGGAGACCATGGATCAGTACCACTTTTGCTACGATGTGGCCCTGGAGTACTTGGAGGGGCTGGAGTCAAGATAGCGGGGCCCTGGCCTGGGGCACCCACT GCACACTCAGGGCCAGACCCACCATCCTGGACTGGCGAGGAAGATCAGTGCCTCCTGCTCTGCCCAAACACACTCCCATGGGGCAAGCACTGGAGTGGAT GCTGGGCTATCTTGCTCCCCCTTCCACTGTGGGCAGGGCCTTTCGCTTGTCCCATGGGCGGGTGGTGGGCCAAGGAGGAGCTTAGCAAGTCTGCAGCCCA GCCCCACCTCCATAGGGTCCTGCAGGCCTGTGCTGAGAGGCCTGGTGCTGCCTGGCAGAGTGACAAAGGCTCAGGACGGCTGGCTCTGGGGGACTCAGGC CAAGCCCCTTGGCACCATCCTGGCTTTTGGCAGGGATGAGTGAGGCCCTGCAGAGAGCATCCCAGGCCAAGGTTCCCACTCAGCCTGCCCCCTCTGCATG TGGGTAGAGGATGTACTGGGACTTGGCATTTAGGATTCCATCTGGCCCAGCCCCTGAAGGTCCTGGGGAAGCAGGTCTCAATTCTGAATAGCCAGTGGGG CACACTGACTGTCCTCCCCAGGGGAACTGCAGCGCCCTCCTCCCCACTGCCCCCTGCAGCCCCTGAGATATTTTGCTCACTATCCCTCCCCACTTGCTTC CCTGATATGTGCTCTGAGCTTCCCTGAACCAGGATCTGCCTATTACTGCTGTGCCCCATGGGGGGCTCCTTCCCTGCCTGACCCACTGTTGCAGAATGAA GTCACCTCGCCCCCCTCTTCCTTTAATCTTCAGGCCTCACTGGCCTGTCCTGCTCAGCTTGGGCCAGTGACAATCTGCAAGGCTGAACAACAGCCCCTGG GGTTGAGGCCCCTGTGGCTCCTGGTCAGGCTGCCCGTTGTGGGGAGGGGCAGTGTTAGAGCAGGGCTGGTCATACCCTCTGGAGTTCAGAGGAAGAGGTA GGACCAGTGCTTTTTTGTTTCTTTTGTTATTTTTGGTTGGGTGGGTGGGAAGGTCTCTTTAAAATGGGGCAGGCCACACCCCCATTCCGTGCCTCAATTT CCCCATCTGTAAACTGTAGATATGACTACTGACCTACCTCGCAGGGGGCTGTGGGGAGGCATAAGCTGATGTTTGTAAAGCGCTTTGTAAATAAACGTGC TCTCTGAATGCCA

refseq_PTPRU.F2 (forward primer)
refseq_PTPRU.R2 (reverse primer)
Single exon skipping

Frame 0

TRRQSRSAPRRSAPARAPARLGLGSGSGGGVPR AGPRDGRRRSNHGPCPGARAGTHLPALRAGDRDS GSWLHLRGGK*PSSALRVQPGPVR*LPVGASAN PPWHPGTCGPAPRLLLDGQHFPACPRPASPCHL PEPERE*YPLCAVQLLPVQPGRAQPGHPGRLRAR *WGPPGQCCVEYDWIPRPSVAPG*AGCQHFLAQ *ISGAV*GPHLPRPQGLHGPR*HPASQLPLRKG PTLLPPGRRGGQRGPERVVPVHGRGQSGRGRTLP LATAERGAGAGGGRAAHQPPALPGHFPAGCREP RRAGPVPLCVPGPARRGRL*LRGAHRQGAPNSH RAPTAAACWPHLPHHPAQHQLHHWRRADRAQGD* VPHGARALG*GARRQPADLQAVAPRPRHRV*DQ RAAHASRRRRHWPPWATPHQPHQMRRAHEGPQR PGFC*DPGPSADPAVGTTGLQRDALPHLYCVAVL SLHPGQQPQPDHPRVCEDRARCQPLHHQEPAAL SERSREACPH*P*GAQRGQGGHFPDG*GCAQWD CSRVPDLHSTGGHDLPQVGGAPGAQWSHHPV*DQ LPEHRVIRPGSERARPTTYHLQAPQ*DLPCLLQ PAPRHHLPVLRAGPHRQRLRPGGTH*DNH*HLC SQL*LCRHAVTPGRV*EHHHRAAEAGTGPRCAHQ CVPGDCGGGAGAEAAAGARWTGLLPSAIDLRGG AGPRPGALLRGRTGGQQST*GHALYRG*QPDLP RLLEPTT*A*EGLSHLLPGSKPPEGGDPAELHPH CQESCLQGKQAAPGGVPEIGGDGAYPGHLCRGA CCPHPSPGCHHCHHPQRERPLCLLLLPEAGEHD QGHRQLPPGEDTHDERRGPQLHRPEHPAGGRAAG PVLHGHPWLQHPGRPAQRWGH*GQQPPGGLPEA SLWPEGLPIPHGAAAPCGACRRPSAAHQPDEDG RGLRLQAGV*ELL*RLGRHKEERQGQGQPAGANA CL*SAPSETAPDAGRPQCRLH*CQLHRWLPQVK PLHSHSRAEA*DGL*LLAYGVAGALFQHRHDHQ AGRGGQGEMLTVLAGGLRHLRGHQDYAGEDRDPG *VCRAHFCPGAERLLCPARGPPVPLHSVARAWR PLPCHGAAGFHPAREGLHPT*CRAHCHPLQRGH RPHRLLYRPGCDAGHGRV*GRRGHLQLCEDSLLP ACQHDPD*GAVHLHS*CNPGGLPVWGDHHPCQ* VQGHLQGDDPH*SSE*FLPAAGRVPDAELGHPA AGRGGVQHRPVAPEPRQEPQHGRPAARPLPALPH LH*WGLQQLH*CSPD*QLHTECGLHRDPAPAAE HHARLLAAGLRLRVHLHRHAQPAEPVQLRLALP AVLARARPAAIWPHGGGVYVGHS**RLSGSSLPG AEHLSVAGGAPAGAALPVPALVCIPGHT*LQEG LLAPAG*GGQVAGREWGWAHHRALPKRGRTQRH LLRLRHGPGDDPLPQLGGRFLCCQNPPELQTQHG GDHGSVPLLLRCGPGVLGGAGVKIAGPWPGAPT AHSGPDPPSWTGEEDQCLLLCPNTLPWGKHWSG CWAILLPLPLWAGPFACPMGGWWAKEELSKSAAQ PHLHRVLQACAERPGAAWQSDKGSGRLALGDSG QAPWHHPGFWQG*VRPCREHPRPRFPLSLPPLH VGRGCTGTWHLGFHLAQPLKVLGKQVSILNSQWG TLTVLPRGTAAPSSPLPPAAPEIFCSLSLPTCF PDMCSELP*TRICLLLLCPMGGSFPA*PTVAE* SHLAPLFL*SSGLTGLSCSAWASDNLQG*TTAPG VEAPVAPGQAARCGEGQC*SRAGHTLWSSEEEV GPVLFCFFCYFWLGGWEGLFKMGQATPPFRASI SPSVNCRYDY*PTSQGAVGRHKLMFVKRFVNKRA L*MP

Frame 1

LGASPAPRRAAPLRLGLRLASGWARAPGAASPA PGPGTGGDAPTMARAQALVLALTFQLCAPETET PAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRI HPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIF QSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVR VNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPN EYQVLFEALISPDRRGYMGLDDILLLSYPCAKA PHFSRLGDVEVNAGQNASFQCMAAGRAAEAERF LLQRQSGALVPAAGVRHISHRRFLATFPLAAVSR AEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPI APPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEI EYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEIS VLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKG LAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLC YHYTLGSSHNQTIRECVKTEQGVSRYTIKNLLPY RNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGI AAESLTFTPLEDMIFLKWEEPQEPNGLITQYEI SYQSIESSDPAVNVPGPRRTISKLRNETYHVFSN LHPGTTYLFSVRARTGKGFGQAALTEITTNISA PSFDYADMPSPLGESENTITVLLRPAQGRGAPI SVYQVIVEEERARRLRREPGGQDCFPVPLTFEAA LARGLVHYFGAELAASSLPEAMPFTVGDNQTYR GFWNPPLEPRKAYLIYFQAASHLKGETRLNCIR IARKAACKESKRPLEVSQRSEEMGLILGICAGGL AVLILLLGAIIVIIRKGRDHYAYSYYPKPVNMT KATVNYRQEKTHMMSAVDRSFTDQSTLQEDERL GLSFMDTHGYSTRGDQRSGGVTEASSLLGGSPRR PCGRKGSPYHTGQLHPAVRVADLLQHINQMKTA EGYGFKQEYESFFEGWDATKKKDKVKGSRQEPM PAYDRHRVKLHPMLGDPNADYINANYIDGYHRSN HFIATQGPKPEMVYDFWRMVWQEHCSSIVMITK LVEVGRVKCSRYWPEDSDTYGDIKIMLVKTETL AEYVVRTFALERRGYSARHEVRQFHFTAWPEHGV PYHATGLLAFIRRVKASTPPDAGPIVIHCSAGT GRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCS RRVNMIQTEEQYIFIHDAILEACLCGETTIPVSE FKATYKEMIRIDPQSNSSQLREEFQTLNSVTPP LDVEECSIALLPRNRDKNRSMDVLPPDRCLPFL ISTDGDSNNYINAALTDSYTRSAAFIVTLHPLQS TTPDFWRLVYDYGCTSIVMLNQLNQSNSAWPCL QYWPEPGRQQYGLMEVEFMSGTADEDLVARVFR VQNISRLQEGHLLVRHFQFLRWSAYRDTPDSKKA FLHLLAEVDKWQAESGDGRTIVHCLNGGGRSGT FCACATVLEMIRCHNLVDVFFAAKTLRNYKPNM VETMDQYHFCYDVALEYLEGLESR*RGPGLGHPL HTQGQTHHPGLARKISASCSAQTHSHGASTGVD AGLSCSPFHCGQGLSLVPWAGGGPRRSLASLQP SPTSIGSCRPVLRGLVLPGRVTKAQDGWLWGTQA KPLGTILAFGRDE*GPAESIPGQGSHSACPLCM WVEDVLGLGI*DSIWPSP*RSWGSRSQF*IASG AH*LSSPGELQRPPPHCPLQPLRYFAHYPSPLAS LICALSFPEPGSAYYCCAPWGAPSLPDPLLQNE VTSPPSSFNLQASLACPAQLGPVTICKAEQQPL GLRPLWLLVRLPVVGRGSVRAGLVIPSGVQRKR* DQCFFVSFVIFGWVGGKVSLKWGRPHPHSVPQF PHL*TVDMTTDLPRRGLWGGIS*CL*SAL*INV LSEC

Frame 2

SAPVPLRAAPLRSGSGSGSPRAGLGLRGRRPPR RAPGRAATLQPWPVPRRSCWHSPSSSARRRPRL RQLAAPSRRQVTQQCPASTARPSTMTSSGSKCE STLAPGHLRTCPTAPT*WSTLPSMPQASEPMSSS RA*ARMIPTVCSSATSCTAGTGTARAPWASTCA LMGAPWAVLCGI*LDPTAVSGTRLSWLSALSGP MNIRCCLRPSSPQTAGATWA*MTSCFSATPAQRP HTSPAWATWRSTRARTRRSSAWPRAERPRPNAS SCNGRAGRWCRRRACGTSATGASWPLSRWLP*A APSRTCTAVCPRPRAARASLTSRSSSSRSPQLPS RPHSCCVLAPPTSSSSSTPTPSLATGRSCARRL STAWRAGPGLRCTPSACRPTSCGTSTPTQSMRS ACCSRVPETAALAALGHPSSAAPNAQSP*GPPKA WLLLRSRPVS*PCSGNHWATT*RVATPILCRCA ITTPWAAATTRPSESV*RQSKVSAATPSRTCCP IGTFT*GLSSLTLRGAKRARRSLSRRMRMCPVGL QPSP*PSLHWRT*SSSSGRSPRSPMVSSPSMRS ATRASSHQTRQ*TCQAHDVPSPSSAMRPTMSSP TCTQAPPTCSPCGPAQAKASARRHSLR*PLTSLL PALIMPTCRHPWASLRTPSPCC*GRHRAAVRPS VCTR*LWRRSGRGGCGGSQVDRTASQCH*PSRR RWPEAWCTTSGPNWRPAVYLRPCPLPWVTTRPTE ASGTHHLSLGRPISSTSRQQAT*RGRPG*IASA LPGKLPARKASGPWRCPRDRRRWGLSWASVQGG LLSSSFSWVPSLSSSAKGETTMPTPTTRSR*T*P RPPSTTARRRHT**APWTAASQTRAPCRRTSGW ACPSWTPMATAPGETSAAVGSLRPAASWGAPRG VPVAGRAPHTTRGSCTLRCVSQTFCSTSTR*RRP RVTASSRSMRASLKAGTPQRRKTRSRAAGRSQC LPMIGTE*NCTRCWETPMPTTLMPTT*MVTTGQ TTS*PLKGRSLRWSMTSGVWCGRSTVPASS*SPS WSRWAG*NAHGTGRRTQTPTGTSRLCW*RQRPW LSMSCALLPWSGEATLPGTRSASSTSQRGQSMA SPTMPRGCWLSSGA*RPPPHLMPGPLSSTAARAP AAQVAISSWM*CWTWQSVRASWTFTTV*RLSAP GVST*SRLRSSTSSFMMQSWRPACVGRPPSLSV SSRPPTRR*SALILRVIPPSCGKSSRR*TRSPRR WTWRSAASPCCPGTATRTAAWTSCRPTAACPSS SPLMGTPTTTLMQP*LTATHGVRPSS*PCTRCR APRPTSGGWSTITGAPPSSCSTS*TSPTPPGPAC STGQSQAGSNMASWRWSLCRAQLMKT*WLESSG CRTSLGCRRGTCWCGTSSSCAGLHTGTHLTPRR PSCTCWLRWTSGRPRVGMGAPSCTA*TGEDAAAP SAPAPRSWR*SAATTWWTFSLLPKPSGTTNPTW WRPWISTTFATMWPWSTWRGWSQDSGALAWGTH CTLRARPTILDWRGRSVPPALPKHTPMGQALEWM LGYLAPPSTVGRAFRLSHGRVVGQGGA*QVCSP APPP*GPAGLC*EAWCCLAE*QRLRTAGSGGLR PSPLAPSWLLAGMSEALQRASQAKVPTQPAPSAC G*RMYWDLAFRIPSGPAPEGPGEAGLNSE*PVG HTDCPPQGNCSALLPTAPCSP*DILLTIPPHLL P*YVL*ASLNQDLPITAVPHGGLLPCLTHCCRMK SPRPPLPLIFRPHWPVLLSLGQ*QSARLNNSPW G*GPCGSWSGCPLWGGAVLEQGWSYPLEFRGRG RTSAFLFLLLFLVGWVGRSL*NGAGHTPIPCLNF PICKL*I*LLTYLAGGCGEA*ADVCKALCK*TC SLNA

Sequence NM_133177

ACTCGGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCG CCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTC CGGCAGCTGGCTGCACCTTCGAGGAGGCAAGTGACCCAGCAGTGCCCTGCGAGTACAGCCAGGCCCAGTACGATGACTTCCAGTGGGAGCAAGTGCGAAT CCACCCTGGCACCCGGGCACCTGCGGACCTGCCCCACGGCTCCTACTTGATGGTCAACACTTCCCAGCATGCCCCAGGCCAGCGAGCCCATGTCATCTTC CAGAGCCTGAGCGAGAATGATACCCACTGTGTGCAGTTCAGCTACTTCCTGTACAGCCGGGACGGGCACAGCCCGGGCACCCTGGGCGTCTACGTGCGCG TTAATGGGGGCCCCCTGGGCAGTGCTGTGTGGAATATGACTGGATCCCACGGCCGTCAGTGGCACCAGGCTGAGCTGGCTGTCAGCACTTTCTGGCCCAA TGAATATCAGGTGCTGTTTGAGGCCCTCATCTCCCCAGACCGCAGGGGCTACATGGGCCTAGATGACATCCTGCTTCTCAGCTACCCCTGCGCAAAGGCC CCACACTTCTCCCGCCTGGGCGACGTGGAGGTCAACGCGGGCCAGAACGCGTCGTTCCAGTGCATGGCCGCGGGCAGAGCGGCCGAGGCCGAACGCTTCC TCTTGCAACGGCAGAGCGGGGCGCTGGTGCCGGCGGCGGGCGTGCGGCACATCAGCCACCGGCGCTTCCTGGCCACTTTCCCGCTGGCTGCCGTGAGCCG CGCCGAGCAGGACCTGTACCGCTGTGTGTCCCAGGCCCCGCGCGGCGCGGGCGTCTCTAACTTCGCGGAGCTCATCGTCAAGGAGCCCCCAACTCCCATC GCGCCCCCACAGCTGCTGCGTGCTGGCCCCACCTACCTCATCATCCAGCTCAACACCAACTCCATCATTGGCGACGGGCCGATCGTGCGCAAGGAGATTG AGTACCGCATGGCGCGCGGGCCCTGGGCTGAGGTGCACGCCGTCAGCCTGCAGACCTACAAGCTGTGGCACCTCGACCCCGACACAGAGTATGAGATCAG CGTGCTGCTCACGCGTCCCGGAGACGGCGGCACTGGCCGCCCTGGGCCACCCCTCATCAGCCGCACCAAATGCGCAGAGCCCATGAGGGCCCCCAAAGGC CTGGCTTTTGCTGAGATCCAGGCCCGTCAGCTGACCCTGCAGTGGGAACCACTGGGCTACAACGTGACGCGTTGCCACACCTATACTGTGTCGCTGTGCT ATCACTACACCCTGGGCAGCAGCCACAACCAGACCATCCGAGAGTGTGTGAAGACAGAGCAAGGTGTCAGCCGCTACACCATCAAGAACCTGCTGCCCTA TCGGAACGTTCACGTGAGGCTTGTCCTCACTAACCCTGAGGGGCGCAAAGAGGGCAAGGAGGTCACTTTCCAGACGGATGAGGATGTGCCCAGTGGGATT GCAGCCGAGTCCCTGACCTTCACTCCACTGGAGGACATGATCTTCCTCAAGTGGGAGGAGCCCCAGGAGCCCAATGGTCTCATCACCCAGTATGAGATCA GCTACCAGAGCATCGAGTCATCAGACCCGGCAGTGAACGTGCCAGGCCCACGACGTACCATCTCCAAGCTCCGCAATGAGACCTACCATGTCTTCTCCAA CCTGCACCCAGGCACCACCTACCTGTTCTCCGTGCGGGCCCGCACAGGCAAAGGCTTCGGCCAGGCGGCACTCACTGAGATAACCACTAACATCTCTGCT CCCAGCTTTGATTATGCCGACATGCCGTCACCCCTGGGCGAGTCTGAGAACACCATCACCGTGCTGCTGAGGCCGGCACAGGGCCGCGGTGCGCCCATCA GTGTGTACCAGGTGATTGTGGAGGAGGAGCGGGCGCGGAGGCTGCGGCGGGAGCCAGGTGGACAGGACTGCTTCCCAGTGCCATTGACCTTCGAGGCGGC GCTGGCCCGAGGCCTGGTGCACTACTTCGGGGCCGAACTGGCGGCCAGCAGTCTACCTGAGGCCATGCCCTTTACCGTGGGTGACAACCAGACCTACCGA GGCTTCTGGAACCCACCACTTGAGCCTAGGAAGGCCTATCTCATCTACTTCCAGGCAGCAAGCCACCTGAAGGGGGAGACCCGGCTGAATTGCATCCGCA TTGCCAGGAAAGCTGCCTGCAAGGAAAGCAAGCGGCCCCTGGAGGTGTCCCAGAGATCGGAGGAGATGGGGCTTATCCTGGGCATCTGTGCAGGGGGGCT TGCTGTCCTCATCCTTCTCCTGGGTGCCATCATTGTCATCATCCGCAAAGGGAAGCCGGTGAACATGACCAAGGCCACCGTCAACTACCGCCAGGAGAAG ACACACATGATGAGCGCCGTGGACCGCAGCTTCACAGACCAGAGCACCCTGCAGGAGGACGAGCGGCTGGGCCTGTCCTTCATGGACACCCATGGCTACA GCACCCGGGGAGACCAGCGCAGCGGTGGGGTCACTGAGGCCAGCAGCCTCCTGGGGGGCTCCCCGAGGCGTCCCTGTGGCCGGAAGGGCTCCCCATACCA CACGGGGCAGCTGCACCCTGCGGTGCGTGTCGCAGACCTTCTGCAGCACATCAACCAGATGAAGACGGCCGAGGGTTACGGCTTCAAGCAGGAGTATGAG AGCTTCTTTGAAGGCTGGGACGCCACAAAGAAGAAAGACAAGGTCAAGGGCAGCCGGCAGGAGCCAATGCCTGCCTATGATCGGCACCGAGTGAAACTGC ACCCGATGCTGGGAGACCCCAATGCCGACTACATTAATGCCAACTACATAGATATTCGGATAAACCGAGAAGGTTACCACAGGTCAAACCACTTCATAGC CACTCAAGGGCCGAAGCCTGAGATGGTCTATGACTTCTGGCGTATGGTGTGGCAGGAGCACTGTTCCAGCATCGTCATGATCACCAAGCTGGTCGAGGTG GGCAGGGTGAAATGCTCACGGTACTGGCCGGAGGACTCAGACACCTACGGGGACATCAAGATTATGCTGGTGAAGACAGAGACCCTGGCTGAGTATGTCG TGCGCACTTTTGCCCTGGAGCGGAGAGGCTACTCTGCCCGGCACGAGGTCCGCCAGTTCCACTTCACAGCGTGGCCAGAGCATGGCGTCCCCTACCATGC CACGGGGCTGCTGGCTTTCATCCGGCGCGTGAAGGCCTCCACCCCACCTGATGCCGGGCCCATTGTCATCCACTGCAGCGCGGGCACCGGCCGCACAGGT TGCTATATCGTCCTGGATGTGATGCTGGACATGGCAGAGTGTGAGGGCGTCGTGGACATTTACAACTGTGTGAAGACTCTCTGCTCCCGGCGTGTCAACA TGATCCAGACTGAGGAGCAGTACATCTTCATTCATGATGCAATCCTGGAGGCCTGCCTGTGTGGGGAGACCACCATCCCTGTCAGTGAGTTCAAGGCCAC CTACAAGGAGATGATCCGCATTGATCCTCAGAGTAATTCCTCCCAGCTGCGGGAAGAGTTCCAGACGCTGAACTCGGTCACCCCGCCGCTGGACGTGGAG GAGTGCAGCATCGCCCTGTTGCCCCGGAACCGCGACAAGAACCGCAGCATGGACGTCCTGCCGCCCGACCGCTGCCTGCCCTTCCTCATCTCCACTGATG GGGACTCCAACAACTACATTAATGCAGCCCTGACTGACAGCTACACACGGAGTGCGGCCTTCATCGTGACCCTGCACCCGCTGCAGAGCACCACGCCCGA CTTCTGGCGGCTGGTCTACGATTACGGGTGCACCTCCATCGTCATGCTCAACCAGCTGAACCAGTCCAACTCCGCCTGGCCCTGCCTGCAGTACTGGCCA GAGCCAGGCCGGCAGCAATATGGCCTCATGGAGGTGGAGTTTATGTCGGGCACAGCTGATGAAGACTTAGTGGCTCGAGTCTTCCGGGTGCAGAACATCT CTCGGGAGGGGCACCTGCTGGTGCGGCACTTCCAGTTCCTGCGCTGGTCTGCATACCGGGACACACCTGACTCCAAGAAGGCCTTCTTGCACCTGCTGGC TGAGGTGGACAAGTGGCAGGCCGAGAGTGGGGATGGGCGCACCATCGTGCACTGCCTAAACGGGGGAGGACGCAGCGGCACCTTCTGCGCCTGCGCCACG GTCCTGGAGATGATCCGCTGCCACAACTTGGTGGACGTTTTCTTTGCTGCCAAAACCCTCCGGAACTACAAACCCAACATGGTGGAGACCATGGATCAGT ACCACTTTTGCTACGATGTGGCCCTGGAGTACTTGGAGGGGCTGGAGTCAAGATAGCGGGGCCCTGGCCTGGGGCACCCACTGCACACTCAGGGCCAGAC CCACCATCCTGGACTGGCGAGGAAGATCAGTGCCTCCTGCTCTGCCCAAACACACTCCCATGGGGCAAGCACTGGAGTGGATGCTGGGCTATCTTGCTCC CCCTTCCACTGTGGGCAGGGCCTTTCGCTTGTCCCATGGGCGGGTGGTGGGCCAAGGAGGAGCTTAGCAAGTCTGCAGCCCAGCCCCACCTCCATAGGGT CCTGCAGGCCTGTGCTGAGAGGCCTGGTGCTGCCTGGCAGAGTGACAAAGGCTCAGGACGGCTGGCTCTGGGGGACTCAGGCCAAGCCCCTTGGCACCAT CCTGGCTTTTGGCAGGGATGAGTGAGGCCCTGCAGAGAGCATCCCAGGCCAAGGTTCCCACTCAGCCTGCCCCCTCTGCATGTGGGTAGAGGATGTACTG GGACTTGGCATTTAGGATTCCATCTGGCCCAGCCCCTGAAGGTCCTGGGGAAGCAGGTCTCAATTCTGAATAGCCAGTGGGGCACACTGACTGTCCTCCC CAGGGGAACTGCAGCGCCCTCCTCCCCACTGCCCCCTGCAGCCCCTGAGATATTTTGCTCACTATCCCTCCCCACTTGCTTCCCTGATATGTGCTCTGAG CTTCCCTGAACCAGGATCTGCCTATTACTGCTGTGCCCCATGGGGGGCTCCTTCCCTGCCTGACCCACTGTTGCAGAATGAAGTCACCTCGCCCCCCTCT TCCTTTAATCTTCAGGCCTCACTGGCCTGTCCTGCTCAGCTTGGGCCAGTGACAATCTGCAAGGCTGAACAACAGCCCCTGGGGTTGAGGCCCCTGTGGC TCCTGGTCAGGCTGCCCGTTGTGGGGAGGGGCAGTGTTAGAGCAGGGCTGGTCATACCCTCTGGAGTTCAGAGGAAGAGGTAGGACCAGTGCTTTTTTGT TTCTTTTGTTATTTTTGGTTGGGTGGGTGGGAAGGTCTCTTTAAAATGGGGCAGGCCACACCCCCATTCCGTGCCTCAATTTCCCCATCTGTAAACTGTA GATATGACTACTGACCTACCTCGCAGGGGGCTGTGGGGAGGCATAAGCTGATGTTTGTAAAGCGCTTTGTAAATAAACGTGCTCTCTGAATGCCA

refseq_PTPRU.F2 (forward primer)
refseq_PTPRU.R2 (reverse primer)
Single exon skipping

Frame 0

TRRQSRSAPRRSAPARAPARLGLGSGSGGGVPR AGPRDGRRRSNHGPCPGARAGTHLPALRAGDRDS GSWLHLRGGK*PSSALRVQPGPVR*LPVGASAN PPWHPGTCGPAPRLLLDGQHFPACPRPASPCHL PEPERE*YPLCAVQLLPVQPGRAQPGHPGRLRAR *WGPPGQCCVEYDWIPRPSVAPG*AGCQHFLAQ *ISGAV*GPHLPRPQGLHGPR*HPASQLPLRKG PTLLPPGRRGGQRGPERVVPVHGRGQSGRGRTLP LATAERGAGAGGGRAAHQPPALPGHFPAGCREP RRAGPVPLCVPGPARRGRL*LRGAHRQGAPNSH RAPTAAACWPHLPHHPAQHQLHHWRRADRAQGD* VPHGARALG*GARRQPADLQAVAPRPRHRV*DQ RAAHASRRRRHWPPWATPHQPHQMRRAHEGPQR PGFC*DPGPSADPAVGTTGLQRDALPHLYCVAVL SLHPGQQPQPDHPRVCEDRARCQPLHHQEPAAL SERSREACPH*P*GAQRGQGGHFPDG*GCAQWD CSRVPDLHSTGGHDLPQVGGAPGAQWSHHPV*DQ LPEHRVIRPGSERARPTTYHLQAPQ*DLPCLLQ PAPRHHLPVLRAGPHRQRLRPGGTH*DNH*HLC SQL*LCRHAVTPGRV*EHHHRAAEAGTGPRCAHQ CVPGDCGGGAGAEAAAGARWTGLLPSAIDLRGG AGPRPGALLRGRTGGQQST*GHALYRG*QPDLP RLLEPTT*A*EGLSHLLPGSKPPEGGDPAELHPH CQESCLQGKQAAPGGVPEIGGDGAYPGHLCRGA CCPHPSPGCHHCHHPQREAGEHDQGHRQLPPGE DTHDERRGPQLHRPEHPAGGRAAGPVLHGHPWLQ HPGRPAQRWGH*GQQPPGGLPEASLWPEGLPIP HGAAAPCGACRRPSAAHQPDEDGRGLRLQAGV* ELL*RLGRHKEERQGQGQPAGANACL*SAPSETA PDAGRPQCRLH*CQLHRYSDKPRRLPQVKPLHS HSRAEA*DGL*LLAYGVAGALFQHRHDHQAGRG GQGEMLTVLAGGLRHLRGHQDYAGEDRDPG*VCR AHFCPGAERLLCPARGPPVPLHSVARAWRPLPC HGAAGFHPAREGLHPT*CRAHCHPLQRGHRPHR LLYRPGCDAGHGRV*GRRGHLQLCEDSLLPACQH DPD*GAVHLHS*CNPGGLPVWGDHHPCQ*VQGH LQGDDPH*SSE*FLPAAGRVPDAELGHPAAGRG GVQHRPVAPEPRQEPQHGRPAARPLPALPHLH*W GLQQLH*CSPD*QLHTECGLHRDPAPAAEHHAR LLAAGLRLRVHLHRHAQPAEPVQLRLALPAVLA RARPAAIWPHGGGVYVGHS**RLSGSSLPGAEHL SGGAPAGAALPVPALVCIPGHT*LQEGLLAPAG *GGQVAGREWGWAHHRALPKRGRTQRHLLRLRH GPGDDPLPQLGGRFLCCQNPPELQTQHGGDHGSV PLLLRCGPGVLGGAGVKIAGPWPGAPTAHSGPD PPSWTGEEDQCLLLCPNTLPWGKHWSGCWAILL PLPLWAGPFACPMGGWWAKEELSKSAAQPHLHRV LQACAERPGAAWQSDKGSGRLALGDSGQAPWHH PGFWQG*VRPCREHPRPRFPLSLPPLHVGRGCT GTWHLGFHLAQPLKVLGKQVSILNSQWGTLTVLP RGTAAPSSPLPPAAPEIFCSLSLPTCFPDMCSE LP*TRICLLLLCPMGGSFPA*PTVAE*SHLAPL FL*SSGLTGLSCSAWASDNLQG*TTAPGVEAPVA PGQAARCGEGQC*SRAGHTLWSSEEEVGPVLFC FFCYFWLGGWEGLFKMGQATPPFRASISPSVNC RYDY*PTSQGAVGRHKLMFVKRFVNKRAL*MP

Frame 1

LGASPAPRRAAPLRLGLRLASGWARAPGAASPA PGPGTGGDAPTMARAQALVLALTFQLCAPETET PAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRI HPGTRAPADLPHGSYLMVNTSQHAPGQRAHVIF QSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVR VNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPN EYQVLFEALISPDRRGYMGLDDILLLSYPCAKA PHFSRLGDVEVNAGQNASFQCMAAGRAAEAERF LLQRQSGALVPAAGVRHISHRRFLATFPLAAVSR AEQDLYRCVSQAPRGAGVSNFAELIVKEPPTPI APPQLLRAGPTYLIIQLNTNSIIGDGPIVRKEI EYRMARGPWAEVHAVSLQTYKLWHLDPDTEYEIS VLLTRPGDGGTGRPGPPLISRTKCAEPMRAPKG LAFAEIQARQLTLQWEPLGYNVTRCHTYTVSLC YHYTLGSSHNQTIRECVKTEQGVSRYTIKNLLPY RNVHVRLVLTNPEGRKEGKEVTFQTDEDVPSGI AAESLTFTPLEDMIFLKWEEPQEPNGLITQYEI SYQSIESSDPAVNVPGPRRTISKLRNETYHVFSN LHPGTTYLFSVRARTGKGFGQAALTEITTNISA PSFDYADMPSPLGESENTITVLLRPAQGRGAPI SVYQVIVEEERARRLRREPGGQDCFPVPLTFEAA LARGLVHYFGAELAASSLPEAMPFTVGDNQTYR GFWNPPLEPRKAYLIYFQAASHLKGETRLNCIR IARKAACKESKRPLEVSQRSEEMGLILGICAGGL AVLILLLGAIIVIIRKGKPVNMTKATVNYRQEK THMMSAVDRSFTDQSTLQEDERLGLSFMDTHGY STRGDQRSGGVTEASSLLGGSPRRPCGRKGSPYH TGQLHPAVRVADLLQHINQMKTAEGYGFKQEYE SFFEGWDATKKKDKVKGSRQEPMPAYDRHRVKL HPMLGDPNADYINANYIDIRINREGYHRSNHFIA TQGPKPEMVYDFWRMVWQEHCSSIVMITKLVEV GRVKCSRYWPEDSDTYGDIKIMLVKTETLAEYV VRTFALERRGYSARHEVRQFHFTAWPEHGVPYHA TGLLAFIRRVKASTPPDAGPIVIHCSAGTGRTG CYIVLDVMLDMAECEGVVDIYNCVKTLCSRRVN MIQTEEQYIFIHDAILEACLCGETTIPVSEFKAT YKEMIRIDPQSNSSQLREEFQTLNSVTPPLDVE ECSIALLPRNRDKNRSMDVLPPDRCLPFLISTD GDSNNYINAALTDSYTRSAAFIVTLHPLQSTTPD FWRLVYDYGCTSIVMLNQLNQSNSAWPCLQYWP EPGRQQYGLMEVEFMSGTADEDLVARVFRVQNI SREGHLLVRHFQFLRWSAYRDTPDSKKAFLHLLA EVDKWQAESGDGRTIVHCLNGGGRSGTFCACAT VLEMIRCHNLVDVFFAAKTLRNYKPNMVETMDQ YHFCYDVALEYLEGLESR*RGPGLGHPLHTQGQT HHPGLARKISASCSAQTHSHGASTGVDAGLSCS PFHCGQGLSLVPWAGGGPRRSLASLQPSPTSIG SCRPVLRGLVLPGRVTKAQDGWLWGTQAKPLGTI LAFGRDE*GPAESIPGQGSHSACPLCMWVEDVL GLGI*DSIWPSP*RSWGSRSQF*IASGAH*LSS PGELQRPPPHCPLQPLRYFAHYPSPLASLICALS FPEPGSAYYCCAPWGAPSLPDPLLQNEVTSPPS SFNLQASLACPAQLGPVTICKAEQQPLGLRPLW LLVRLPVVGRGSVRAGLVIPSGVQRKR*DQCFFV SFVIFGWVGGKVSLKWGRPHPHSVPQFPHL*TV DMTTDLPRRGLWGGIS*CL*SAL*INVLSEC

Frame 2

SAPVPLRAAPLRSGSGSGSPRAGLGLRGRRPPR RAPGRAATLQPWPVPRRSCWHSPSSSARRRPRL RQLAAPSRRQVTQQCPASTARPSTMTSSGSKCE STLAPGHLRTCPTAPT*WSTLPSMPQASEPMSSS RA*ARMIPTVCSSATSCTAGTGTARAPWASTCA LMGAPWAVLCGI*LDPTAVSGTRLSWLSALSGP MNIRCCLRPSSPQTAGATWA*MTSCFSATPAQRP HTSPAWATWRSTRARTRRSSAWPRAERPRPNAS SCNGRAGRWCRRRACGTSATGASWPLSRWLP*A APSRTCTAVCPRPRAARASLTSRSSSSRSPQLPS RPHSCCVLAPPTSSSSSTPTPSLATGRSCARRL STAWRAGPGLRCTPSACRPTSCGTSTPTQSMRS ACCSRVPETAALAALGHPSSAAPNAQSP*GPPKA WLLLRSRPVS*PCSGNHWATT*RVATPILCRCA ITTPWAAATTRPSESV*RQSKVSAATPSRTCCP IGTFT*GLSSLTLRGAKRARRSLSRRMRMCPVGL QPSP*PSLHWRT*SSSSGRSPRSPMVSSPSMRS ATRASSHQTRQ*TCQAHDVPSPSSAMRPTMSSP TCTQAPPTCSPCGPAQAKASARRHSLR*PLTSLL PALIMPTCRHPWASLRTPSPCC*GRHRAAVRPS VCTR*LWRRSGRGGCGGSQVDRTASQCH*PSRR RWPEAWCTTSGPNWRPAVYLRPCPLPWVTTRPTE ASGTHHLSLGRPISSTSRQQAT*RGRPG*IASA LPGKLPARKASGPWRCPRDRRRWGLSWASVQGG LLSSSFSWVPSLSSSAKGSR*T*PRPPSTTARRR HT**APWTAASQTRAPCRRTSGWACPSWTPMAT APGETSAAVGSLRPAASWGAPRGVPVAGRAPHT TRGSCTLRCVSQTFCSTSTR*RRPRVTASSRSMR ASLKAGTPQRRKTRSRAAGRSQCLPMIGTE*NC TRCWETPMPTTLMPTT*IFG*TEKVTTGQTTS* PLKGRSLRWSMTSGVWCGRSTVPASS*SPSWSRW AG*NAHGTGRRTQTPTGTSRLCW*RQRPWLSMS CALLPWSGEATLPGTRSASSTSQRGQSMASPTM PRGCWLSSGA*RPPPHLMPGPLSSTAARAPAAQV AISSWM*CWTWQSVRASWTFTTV*RLSAPGVST *SRLRSSTSSFMMQSWRPACVGRPPSLSVSSRP PTRR*SALILRVIPPSCGKSSRR*TRSPRRWTWR SAASPCCPGTATRTAAWTSCRPTAACPSSSPLM GTPTTTLMQP*LTATHGVRPSS*PCTRCRAPRP TSGGWSTITGAPPSSCSTS*TSPTPPGPACSTGQ SQAGSNMASWRWSLCRAQLMKT*WLESSGCRTS LGRGTCWCGTSSSCAGLHTGTHLTPRRPSCTCW LRWTSGRPRVGMGAPSCTA*TGEDAAAPSAPAPR SWR*SAATTWWTFSLLPKPSGTTNPTWWRPWIS TTFATMWPWSTWRGWSQDSGALAWGTHCTLRAR PTILDWRGRSVPPALPKHTPMGQALEWMLGYLAP PSTVGRAFRLSHGRVVGQGGA*QVCSPAPPP*G PAGLC*EAWCCLAE*QRLRTAGSGGLRPSPLAP SWLLAGMSEALQRASQAKVPTQPAPSACG*RMYW DLAFRIPSGPAPEGPGEAGLNSE*PVGHTDCPP QGNCSALLPTAPCSP*DILLTIPPHLLP*YVL* ASLNQDLPITAVPHGGLLPCLTHCCRMKSPRPPL PLIFRPHWPVLLSLGQ*QSARLNNSPWG*GPCG SWSGCPLWGGAVLEQGWSYPLEFRGRGRTSAFL FLLLFLVGWVGRSL*NGAGHTPIPCLNFPICKL* I*LLTYLAGGCGEA*ADVCKALCK*TCSLNA