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Sequences

Sequence NM_147150

CCCGGGCGAGCCCGCCGTGCGCACAGCTCTGCCCGCCGCCCCTGGAGCGGATCCCCAGCCGTCCCTGGGCGTTCTCCCGGGTTCTAGCAAAGCCCCCCGG
GGTGCCCATCAGTTTCCTTGGGTGACTACAGCGTGTGTTTTTTCTTTCCTCTTTCCCCTGCCTGTGTGCCCTTCTCCAGGATGGCAGAGGCGGAATTGCA
CAAGGAAAGGCTGCAAGCCATAGCAGAAAAAAGAAAGAGGCAGACTGAAATAGAAGGCAAGCGACAACAGCTTGACGAGCAGATACTTCTGCTGCAGCAT
TCCAAGTCCAAAGTGCTTCGGGAGAAATGGCTGCTGCAGGGCATACCCGCTGGAACTGCCGAAGAGGAGGAAGCCAGGAGGCGGCAGTCTGAAGAGGATG
AGTTCAGAGTCAAGCAACTTGAAGATAACATTCAGAGGCTGGAGCAAGAAATACAAACGCTAGAAAGTGAAGAGTCCCAGATATCTGCCAAAGAGCAAAT
CATCCTAGAGAAACTGAAGGAAACAGAAAAATCCTTCAAGGACTTTCAGAAGGGTTTCTCCAGTACGGATGGAGATGCAGTAAATTACATTTCCTCCCAG
CTTCCCGACCTGCCAATCCTCTGTTCACGAACAGCAGAACCATCACCTGGGCAGGACGGGACCAGCAGAGCGGCTGGAGTCGGGTGGGAGAATGTGCTGC
TAAAGGAAGGTGAGTCAGCCTCGAACGCCACAGAAACATCCGGCCCAGACATGACTATCAAGAAGCCTCCCCAGCTTTCTGAGGATGATATCTGGCTAAA
AAGCGAGGGAGACAACTATAGTGCCACCCTCCTGGAGCCTGCTGCCAGCTCTCTTTCCCCAGATCACAAAAACATGGAAATTGAGGTGTCTGTTGCAGAA
TGTAAAAGTGTTCCTGGAATCACCTCTACCCCACATCCCATGGACCATCCCTCCGCTTTCTATTCACCCCCGCATAATGGCCTCCTTACTGATCACCACG
AATCCCTGGATAATGATGTTGCCAGAGAGATCCGCTATCTAGATGAGGTGCTAGAGGCCAACTGCTGTGATTCTGCTGTGGATGGAACGTACAATGGAAC
ATCCTCCCCAGAGCCTGGTGCAGTGGTTCTGGTGGGCGGCCTAAGCCCCCCTGTCCACGAGGCGACCCAGCCAGAACCCACTGAAAGAACAGCTAGCCGG
CAGGCACCTCCTCACATCGAGCTCAGTAATAGCAGCCCTGACCCCATGGCAGAGGCAGAAAGAACAAATGGCCATTCCCCCAGCCAGCCTAGAGATGCGC
TGGGGGACAGCCTGCAGGTGCCTGTCAGCCCCAGCTCCACAACCAGCTCACGGTGTTCTTCCCGAGATGGAGAGTTCACTCTCACCACACTGAAAAAGGA
GGCCAAGTTTGAGCTGCGTGCCTTCCATGAGGACAAGAAGCCCTCCAAGCTCTTTGAGGATGACGAGCATGAGAAAGAACAATACTGCATTAGAAAAGTG
AGGCCTTCAGAGGAGATGCTGGAGCTGGAAAAGGAGAGGAGAGAGCTCATCCGCAGCCAGGCCGTCAAGAAGAATCCTGGCATTGCAGCAAAATGGTGGA
ATCCCCCGCAGGAAAAAACCATCGAGGAGCAGCTGGACGAGGAACATCTGGAGTCGCACAAAAAGTACAAGGAGCGCAAAGAGAGAAGGGCACAGCAGGA
ACAGTTGCTGCTGCAGAAGCAGTTACAGCAGCAGCAGCAGCAGCCCCCATCGCAGCTCTGCACAGCCCCTGCCTCTTCTCATGAACGCGCAAGCATGATT
GACAAAGCAAAGGAGGACATTGTCACAGAGCAGATAGATTTCTCTGCTGCTCGCAAACAATTTCAGCTGATGGAGAATTCCAGGCAAGCGGTGGCCAAGG
GCCAGAGTACACCCAGGCTGTTCTCCATCAAGCCTTTCTACAGGCCTCTGGGGTCAGTCAACTCAGACAAGCCACTGACTAATCCGAGACCACCTTCTGT
CGGGGGACCTCCAGAAGACAGTGGTGCCTCAGCCGCCAAGGGACAGAAATCCCCCGGTGCCCTGGAGACCCCATCGGCAGCAGGAAGCCAGGGCAACACA
GCCTCTCAGGGGAAGGAAGGGCCCTACAGCGAGCCTTCTAAACGTGGGCCCTTATCTAAACTGTGGGCTGAGGATGGAGAATTTACGAGCGCCCGGGCTG
TCCTCACTGTGGTCAAGGATGATGACCATGGGATTTTGGATCAGTTCTCAAGATCTGTCAATGTCTCCTTGACCCAAGAGGAGCTTGACTCTGGTCTGGA
CGAATTGTCGGTGAGGTCTCAGGATACCACAGTCCTGGAGACCCTATCCAATGATTTCAGCATGGACAACATCAGTGACAGCGGGGCATCCAATGAGACA
ACCAATGCCCTCCAGGAAAATTCACTGGCTGATTTTTCTCTGCCCCAGACACCACAAACTGACAACCCCTCAGAGGGCCGAGGAGAAGGCGTCTCCAAGT
CATTTAGTGATCATGGTTTCTATTCCCCTTCCTCCACGCTGGGGGACTCTCCGTTGGTTGATGACCCCTTGGAGTATCAGGCTGGCCTCCTGGTGCAGAA
TGCCATTCAACAAGCCATAGCCGAGCAGGTGGATAAAGCTGTGTCCAAAACCAGCAGGGATGGAGCAGAGCAACAGGGACCTGAAGCGACTGTAGAGGAA
GCTGAAGCTGCGGCTTTCGGCTCAGAAAAGCCTCAGAGCATGTTTGAGCCACCTCAGGTGTCTTCTCCTGTTCAAGAGAAAAGGGATGTATTACCAAAGA
TTCTGCCTGCTGAAGACAGGGCGCTCAGGGAAAGGGGGCCCCCCCAGCCACTGCCAGCTGTGCAGCCCAGTGGCCCGATTAACATGGAGGAGACCAGGCC
CGAAGGAAGCTATTTCAGCAAGTACTCGGAGGCAGCTGAGCTGAGAAGCACAGCCTCCCTCCTGGCCACTCAAGAATCTGACGTGATGGTTGGGCCTTTC
AAGCTGAGGTCCAGGAAACAGCGGACTTTGTCCATGATTGAGGAAGAGATCCGAGCAGCTCAGGAAAGGGAAGAGGAGCTGAAGAGGCAGAGACAAGTCT
TGCAGAGTACGCAGAGCCCCAGGACAAAGAATGCCCCATCACTGCCCTCCAGAACATGCTACAAAACTGCTCCAGGGAAAATAGAGAAAGTCAAACCTCC
TCCATCC
CCCACCACTGAAGGCCCCAGCTTGCAGCCTGACTTAGCCCCTGAAGAGGCTGCCGGAACCCAGCGGCCCAAGAATCTGATGCAGACCCTCATG
GAAGACTATGAGACACACAAATCTAAAAGGCGCGAGAGAATGGATGATAGTAGTGTCCTCGAGGCCACACGGGTTAATCGAAGAAAGAGCGCACTGGCTT
T
GCGCTGGGAAGCAGGGATCTATGCCAACCAGGAGGAAGAAGACAACGAATAAACTTCCTTCAACCCAGGAAGCGTCTTTGGTGCTTGGGAGACCAAGAA
ACCAAGAAATTAACAACTGAAAGCATTTTAATGGACTATTTATTAAAGTGCAAACAAACTCAGCAATCCTTATGTAGACCAGAAGCTGCAATATACAATG
ATGAAAATGAAACGAAAAGGAAGTCCCCCCATCAGACTCTGGACACCCAGGAATCAAAAGAGAAAGGACTTTTTTGGTGACTCAATCCCAGTGTCTGGTT
TGGGGCCAATCTACAATGGATCCAAAAGGACAAAACATGTTACAAGCAAATCAACATAGTTGCTGCAGGCGGAACTGAGACCAGCCTCTCTGGGCGATGA
AGGACAATGGTGGTAGGGCCACTTAGAGAGCAGTAGGGCCCAGGCTGGTGCAGCCTACATGGCACAGGATATTTCCCTGCACCAGTTTCCCACCTGTCAC
TTGCAGCATCAGAGGGTGTTGCATTAACTCCATTTTCTCCAGCAGCCATAAAATGAATGGCGTTTCTCTCCATATTTGCCCAGAAGAGGCAGTTATGATT
CCACTTCTCCTACATTTAATTATTTTTAATTGAGAACAACTCATGATCACAATTCATAAAATCCATATTTTAAGACAATAGTTCTTCATGTCACAAACAC
AATCTATTCTACATGAGGAGGCTGAGAAAGGGGAAGAGAAAAACAAACCAAATGGATGATGTTAGCTTTAGGATCGTGTCTGCTTATAATATTCACTGAT
CTGCAGTTTATGAGAACACATTTTCACAGTTATGTTTCTTCATAGGAAAACTATATTTAGTGGGCAACAACTATTTTTATGATGGGATGGGGGAGTATAT
ACACGTATAGAATCTGTACGCGTTGAACAACTTGGTTCAAGATGGTGGGGGCATTTTTAGAGCGGCAATAATTGAAAAAAAAGGCGAACTCTGCCTTGGA
GAGGTAGATGATAAGAAATAAAAAGGTGTTTATAACTATTTTGTATTATAAAGTGGGCCTTAGAGATAGGAAGAAGAATGATGGATTCCTTTTGGATCAA
TCAGAAAGGAAACACGAAAGAAAAGTCAGGAAGGTAGAGAGAGAAAAAGGGAGGGAAGGAGAAAGAATGGGAATAAAATAAGGAGGTAAGAGATACTATT
TTTGCTGAGCAACCAGTGTGTTTCAGGATGATACAAAGAAAAATATAGAATAGAAATAAGTGCAGGCTTGGAATCAGCTACAAATCCTAAAGATGGGGTG
TGTGTGGATGTGTGTGTGTGTGTGTGTACACCATTGTGTGTTTGTAAAATGTGTATGTTCATGAGTAAGGGTGTGTGTGTGTGTGTATTAAAATTCCAGA
GTGACCGTGGCACTTGGGTGTACAGGTAATTCCTCCAGAGCTGTTTGCTGGCTTCAGGAGTGGAGTGAGAATTTCTTTTTTATGAAAAGGGATATAAAGG
CACCGAGCTGATGCAGTATTTGTAATATTAAGTTGACCTAACAAGGTATTTGCATGAGTCACAATTACAAAGTTTTGAGCGGTTTTGTAATTTGACATTT
AGGAGAGTCTCCTATTTATTCTCATACTTTACATTCATGCTTAGTATACTATAGAGGATGCCAGCTTTAATCTTTCTGTCATTTAAAGCAATATGATAAG
GGTATTCAATAATTGGGTGCCCTAAATTTCTGGATGAGAAAATTTTCAATTCTGGCCATGAGAAAGAAAAAAAAATAAACAGCCTTCTTTTTTTTTCCTT
TGTTTTAAAACTGTGGTTTTTTAAAAAAGCAATAATTAACTCAGACCTCACTAAAAATCATTTTTGTTTTTATATTGTTATGTCATAAGCTCTATTATGT
TATTCTAACAAGTAGCAATTTCACAAAATTTGTATGTAGATGTTAACGCACATTTCCTTTGCTTCTTTTATTAGACTAGTGTTGACTTTGGGGGGGGACA
TTTATTCACAAATGAGAAGTAGGCACAAAGTAAAAAATGGAACCATCTACTAACAAGGATCCTTTAAAACTGCCAAGGGAGCTCTAACTTGAAGCCACAT
CCTACAGATGGCAGCCCAAATAGCACATGGGCAATTGGCACCATCTTTATATGGTTGAGTCTCCTGAATATTTTGAATGAATTCTCAACAAAATGTGCTA
GCCACTGGGGACGCAAAACAAGTAAGATCCCTGTTGCAAGAAATTCATTTTATAGTGAGGGAGGTTGGCATGGAGACTAAAATTCTCAGGAAAATGAGAT
CCGTGTTAGATTAGAAGTCCTGATGTGAAATGGGAGGACTCAGGAAGGAGGATCGTCTTTACCTGAGGATTTCTAGCCAGAGGTCCCAGATGCCTGGGCT
GAGAACCCAGCGATAAGGGGGCGTTCCCAAAGCAGACACAGGGATAAGAACAGAGGAGGCAGCAGCATTGCACAGCCCCAGGCACAGTGGCAGTTAGGAT
GGCTGGAGAGTAGGATAGTTCTATGGGTTGCCCAAAAAATGTGATGCGCTTCATGTTTTCTCTGACTCATGGATCTGGTAGAGACCATAGACATGATATA
GACTAACTTCCCCATTTTTCACAAGAGGAAACCATCCTTATGACTTACCTTAAAGTTTTTTGTTCTGTTTTGAAGGAAACCATGTGCTTCATGAAACCTA
CAGTTGACAAGAGAATGTACAGCTAAGAGAAAAGCTTAAGAGGCCACACTATTCGCGGAATGGCTTTAGAGGCAGATGAAGTGGTCTTTGACCACAGTTG
ATTGAACCAGAGCACTTATTGCTTAAAGAATAACAGAGTTCTAGAGCTGGGGGTTCTTGGGCCATGCTCCGTGTGTGGATAAGGAAAGAAATACTGTTTC
TGGGACTCTCCCACAGTCACAAAGCTGTTTTCACTGTGGCCCCTACATCTCTTAACTTTTGCTATTACTCCTATGCTGCCTTCCGGATTACTGCTGTCTA
TCTTCTTGCTCCACTCACTGAAGATCCTATTATAATCCCATGAAAATGTAAATTACAGTTTACTTGGGAGAGCCAGATTTTCTCTGTGCTCTTGAGTTTT
TTATTCATTCAAGAAACCTTGGGCCACCGCTTTGTACATAGCACCGTGCTAGGCTCTGGGATCCCAAATGGACCCTTTTAACTTTCTGAAGATGGGACCG
TCCCCTGGAGGAAAGTCATTCCTGCCTAATCCATCGAGAGAAAGAGGCTTACGAAAAACTTTGCCTCTGATGCTCAGCCCCACCCCCAAATAGCACACAA
GCTTGTTAACCCCACCTCTTACAAAATGTTTAGATTCTGTAGGTGTTAAAAGCCTTTCTGGAAGTATTGCATTCTGCCGTGTTTATAGGTGTTCACTTTC
CTCCAGAGCTGATTAACTACTGACATGACTTGGCTTTCTCATCCAGAAATTATGGAAACAGGGTCTGTCAGTGGCAGGAGGCCGTGCTGTGTTTTACTTG
GATGACACAATGCAGTTTACTTGCCTCTTCATACCCATGCATGCTGCTCACCCTAGACAATGACATATAAGCCGTATATAGATCAATGTCCACATATATA
TACACACACACATATATATATATAAAGTGTAACAAGGAACACTAAAACAGTGTTGATTCTTGTCTCTGAAGACAAATAATTAAACCTTTTTTTTCCCAAC
TAAAGAATGGATTTAATTAAACTATGTATTGAAAAAAAAGTAGCCTAAGTGTTAGAGATGGTGAATATATTCCATTTTAGTTAAAGAACAAATTTCCTGA
ATTTTAAGCATTCAGTGAGCTGCCAATTTTGATTTTGTGTTGCTCTTTACCCAAATTATTTTTTCTTTGTTTTTCTTTTTTTGGGGGAGGAGGGGAAAAA
AGCAGCAATACTGTGTTTGGAAATTATACTCTGTATCTGGTTTTCCTGTGTATGTTAACCACTTAAATGTTATTATCCTGCTTTGGTTTTAGAGTGATTG
TGAGGCATTCAATGCAAGTATACAGTTATTTTCTCATTAAAATCCAATGTGTGTTGAGTTTTTATAAA
  • refseq_PALM2-AKAP2.F2 (forward primer)
  • refseq_PALM2-AKAP2.R2 (reverse primer)
  • Single exon skipping

Frame 0

PGRARRAHSSARRPWSGSPAVPGRSPGF*QSPP
GCPSVSLGDYSVCFFFPLSPACVPFSRMAEAELH
KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQH
SKSKVLREKWLLQGIPAGTAEEEEARRRQSEED
EFRVKQLEDNIQRLEQEIQTLESEESQISAKEQI
ILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQ
LPDLPILCSRTAEPSPGQDGTSRAAGVGWENVL
LKEGESASNATETSGPDMTIKKPPQLSEDDIWLK
SEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE
CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHH
ESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGT
SSPEPGAVVLVGGLSPPVHEATQPEPTERTASR
QAPPHIELSNSSPDPMAEAERTNGHSPSQPRDA
LGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKE
AKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV
RPSEEMLELEKERRELIRSQAVKKNPGIAAKWW
NPPQEKTIEEQLDEEHLESHKKYKERKERRAQQE
QLLLQKQLQQQQQQPPSQLCTAPASSHERASMI
DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAK
GQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSV
GGPPEDSGASAAKGQKSPGALETPSAAGSQGNT
ASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARA
VLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLD
ELSVRSQDTTVLETLSNDFSMDNISDSGASNET
TNALQENSLADFSLPQTPQTDNPSEGRGEGVSK
SFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQN
AIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE
AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPK
ILPAEDRALRERGPPQPLPAVQPSGPINMEETRP
EGSYFSKYSEAAELRSTASLLATQESDVMVGPF
KLRSRKQRTLSMIEEEIRAAQEREEELKRQRQV
LQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPP
PS
PTTEGPSLQPDLAPEEAAGTQRPKNLMQTLM
EDYETHKSKRRERMDDSSVLEATRVNRRKSALA
L
RWEAGIYANQEEEDNE*TSFNPGSVFGAWETKK
PRN*QLKAF*WTIY*SANKLSNPYVDQKLQYTM
MKMKRKGSPPIRLWTPRNQKRKDFFGDSIPVSG
LGPIYNGSKRTKHVTSKST*LLQAELRPASLGDE
GQWW*GHLESSRAQAGAAYMAQDISLHQFPTCH
LQHQRVLH*LHFLQQP*NEWRFSPYLPRRGSYD
STSPTFNYF*LRTTHDHNS*NPYFKTIVLHVTNT
IYST*GG*ERGREKQTKWMMLALGSCLLIIFTD
LQFMRTHFHSYVSS*ENYI*WATTIFMMGWGSI
YTYRICTR*TTWFKMVGAFLERQ*LKKKANSALE
R*MIRNKKVFITILYYKVGLRDRKKNDGFLLDQ
SERKHERKVRKVEREKGREGERMGIK*GGKRYY
FC*ATSVFQDDTKKNIE*K*VQAWNQLQILKMGC
VWMCVCVCVHHCVFVKCVCS*VRVCVCVY*NSR
VTVALGCTGNSSRAVCWLQEWSENFFFMKRDIK
APS*CSICNIKLT*QGICMSHNYKVLSGFVI*HL
GESPIYSHTLHSCLVYYRGCQL*SFCHLKQYDK
GIQ*LGALNFWMRKFSILAMRKKKK*TAFFFFP
LF*NCGFLKKQ*LTQTSLKIIFVFILLCHKLYYV
ILTSSNFTKFVCRC*RTFPLLLLLD*C*LWGGT
FIHK*EVGTK*KMEPSTNKDPLKLPREL*LEAT
SYRWQPK*HMGNWHHLYMVESPEYFE*ILNKMC*
PLGTQNK*DPCCKKFIL**GRLAWRLKFSGK*D
PC*IRSPDVKWEDSGRRIVFT*GFLARGPRCLG
*EPSDKGAFPKQTQG*EQRRQQHCTAPGTVAVRM
AGE*DSSMGCPKNVMRFMFSLTHGSGRDHRHDI
D*LPHFSQEETILMTYLKVFCSVLKETMCFMKP
TVDKRMYS*EKSLRGHTIRGMALEADEVVFDHS*
LNQSTYCLKNNRVLELGVLGPCSVCG*GKKYCF
WDSPTVTKLFSLWPLHLLTFAITPMLPSGLLLS
IFLLHSLKILL*SHENVNYSLLGRARFSLCS*VF
YSFKKPWATALYIAPC*ALGSQMDPFNFLKMGP
SPGGKSFLPNPSRERGLRKTLPLMLSPTPK*HT
SLLTPPLTKCLDSVGVKSLSGSIAFCRVYRCSLS
SRAD*LLT*LGFLIQKLWKQGLSVAGGRAVFYL
DDTMQFTCLFIPMHAAHPRQ*HISRI*INVHIY
IHTHIYIYKV*QGTLKQC*FLSLKTNN*TFFFPT
KEWI*LNYVLKKK*PKC*RW*IYSILVKEQIS*
ILSIQ*AANFDFVLLFTQIIFSLFFFFWGRRGK
KQQYCVWKLYSVSGFPVYVNHLNVIILLWF*SDC
EAFNASIQLFSH*NPMCVEFL*

Frame 1

PGEPAVRTALPAAPGADPQPSLGVLPGSSKAPR
GAHQFPWVTTACVFSFLFPLPVCPSPGWQRRNC
TRKGCKP*QKKERGRLK*KASDNSLTSRYFCCSI
PSPKCFGRNGCCRAYPLELPKRRKPGGGSLKRM
SSESSNLKITFRGWSKKYKR*KVKSPRYLPKSK
SS*RN*RKQKNPSRTFRRVSPVRMEMQ*ITFPPS
FPTCQSSVHEQQNHHLGRTGPAERLESGGRMCC
*RKVSQPRTPQKHPAQT*LSRSLPSFLRMISG*
KARETTIVPPSWSLLPALFPQITKTWKLRCLLQN
VKVFLESPLPHIPWTIPPLSIHPRIMASLLITT
NPWIMMLPERSAI*MRC*RPTAVILLWMERTME
HPPQSLVQWFWWAA*APLSTRRPSQNPLKEQLAG
RHLLTSSSVIAALTPWQRQKEQMAIPPASLEMR
WGTACRCLSAPAPQPAHGVLPEMESSLSPH*KR
RPSLSCVPSMRTRSPPSSLRMTSMRKNNTALEK*
GLQRRCWSWKRRGESSSAARPSRRILALQQNGG
IPRRKKPSRSSWTRNIWSRTKSTRSAKREGHSR
NSCCCRSSYSSSSSSPHRSSAQPLPLLMNAQA*L
TKQRRTLSQSR*ISLLLANNFS*WRIPGKRWPR
ARVHPGCSPSSLSTGLWGQSTQTSH*LIRDHLL
SGDLQKTVVPQPPRDRNPPVPWRPHRQQEARATQ
PLRGRKGPTASLLNVGPYLNCGLRMENLRAPGL
SSLWSRMMTMGFWISSQDLSMSP*PKRSLTLVW
TNCR*GLRIPQSWRPYPMISAWTTSVTAGHPMRQ
PMPSRKIHWLIFLCPRHHKLTTPQRAEEKASPS
HLVIMVSIPLPPRWGTLRWLMTPWSIRLASWCR
MPFNKP*PSRWIKLCPKPAGMEQSNRDLKRL*RK
LKLRLSAQKSLRACLSHLRCLLLFKRKGMYYQR
FCLLKTGRSGKGGPPSHCQLCSPVARLTWRRPG
PKEAISASTRRQLS*EAQPPSWPLKNLT*WLGLS
S*GPGNSGLCP*LRKRSEQLRKGKRS*RGRDKS
CRVRRAPGQRMPHHCPPEHATKLLQGK*RKSNL
LHP
PPLKAPACSLT*PLKRLPEPSGPRI*CRPSW
KTMRHTNLKGAREWMIVVSSRPHGLIEERAHWL
CAGKQGSMPTRRKKTTNKLPSTQEASLVLGRPR
NQEINN*KHFNGLFIKVQTNSAILM*TRSCNIQ*
*K*NEKEVPPSDSGHPGIKRERTFLVTQSQCLV
WGQSTMDPKGQNMLQANQHSCCRRN*DQPLWAM
KDNGGRAT*RAVGPRLVQPTWHRIFPCTSFPPVT
CSIRGCCINSIFSSSHKMNGVSLHICPEEAVMI
PLLLHLIIFN*EQLMITIHKIHILRQ*FFMSQT
QSILHEEAEKGEEKNKPNG*C*L*DRVCL*YSLI
CSL*EHIFTVMFLHRKTIFSGQQLFL*WDGGVY
TRIESVRVEQLGSRWWGHF*SGNN*KKRRTLPW
RGR**EIKRCL*LFCIIKWALEIGRRMMDSFWIN
QKGNTKEKSGR*REKKGGKEKEWE*NKEVRDTI
FAEQPVCFRMIQRKI*NRNKCRLGISYKS*RWG
VCGCVCVCVYTIVCL*NVYVHE*GCVCVCIKIPE
*PWHLGVQVIPPELFAGFRSGVRISFL*KGI*R
HRADAVFVILS*PNKVFA*VTITKF*AVL*FDI
*ESLLFILILYIHA*YTIEDASFNLSVI*SNMIR
VFNNWVP*ISG*ENFQFWP*ERKKNKQPSFFFL
CFKTVVF*KSNN*LRPH*KSFLFLYCYVISSIM
LF*QVAISQNLYVDVNAHFLCFFY*TSVDFGGGH
LFTNEK*AQSKKWNHLLTRIL*NCQGSSNLKPH
PTDGSPNSTWAIGTIFIWLSLLNILNEFSTKCA
SHWGRKTSKIPVARNSFYSEGGWHGD*NSQENEI
RVRLEVLM*NGRTQEGGSSLPEDF*PEVPDAWA
ENPAIRGRSQSRHRDKNRGGSSIAQPQAQWQLG
WLESRIVLWVAQKM*CASCFL*LMDLVETIDMI*
TNFPIFHKRKPSL*LTLKFFVLF*RKPCAS*NL
QLTRECTAKRKA*EATLFAEWL*RQMKWSLTTV
D*TRALIA*RITEF*SWGFLGHAPCVDKERNTVS
GTLPQSQSCFHCGPYIS*LLLLLLCCLPDYCCL
SSCSTH*RSYYNPMKM*ITVYLGEPDFLCALEF
FIHSRNLGPPLCT*HRARLWDPKWTLLTF*RWDR
PLEESHSCLIHREKEAYEKLCL*CSAPPPNSTQ
AC*PHLLQNV*IL*VLKAFLEVLHSAVFIGVHF
PPELINY*HDLAFSSRNYGNRVCQWQEAVLCFTW
MTQCSLLASSYPCMLLTLDNDI*AVYRSMSTYI
YTHTYIYIKCNKEH*NSVDSCL*RQIIKPFFSQ
LKNGFN*TMY*KKSSLSVRDGEYIPF*LKNKFPE
F*AFSELPILILCCSLPKLFFLCFSFFGGGGEK
SSNTVFGNYTLYLVFLCMLTT*MLLSCFGFRVI
VRHSMQVYSYFLIKIQCVLSFYK

Frame 2

RASPPCAQLCPPPLERIPSRPWAFSRVLAKPPG
VPISFLG*LQRVFFLSSFPCLCALLQDGRGGIA
QGKAASHSRKKKEAD*NRRQATTA*RADTSAAA
FQVQSASGEMAAAGHTRWNCRRGGSQEAAV*RG*
VQSQAT*R*HSEAGARNTNARK*RVPDICQRAN
HPRETEGNRKILQGLSEGFLQYGWRCSKLHFLP
ASRPANPLFTNSRTITWAGRDQQSGWSRVGECAA
KGR*VSLERHRNIRPRHDYQEASPAF*G*YLAK
KRGRQL*CHPPGACCQLSFPRSQKHGN*GVCCR
M*KCSWNHLYPTSHGPSLRFLFTPA*WPPY*SPR
IPG**CCQRDPLSR*GARGQLL*FCCGWNVQWN
ILPRAWCSGSGGRPKPPCPRGDPARTH*KNS*P
AGTSSHRAQ**QP*PHGRGRKNKWPFPQPA*RCA
GGQPAGACQPQLHNQLTVFFPRWRVHSHHTEKG
GQV*AACLP*GQEALQAL*G*RA*ERTILH*KS
EAFRGDAGAGKGEERAHPQPGRQEESWHCSKMVE
SPAGKNHRGAAGRGTSGVAQKVQGAQREKGTAG
TVAAAEAVTAAAAAAPIAALHSPCLFS*TRKHD
*QSKGGHCHRADRFLCCSQTISADGEFQASGGQG
PEYTQAVLHQAFLQASGVSQLRQATD*SETTFC
RGTSRRQWCLSRQGTEIPRCPGDPIGSRKPGQH
SLSGEGRALQRAF*TWALI*TVG*GWRIYERPGC
PHCGQG**PWDFGSVLKICQCLLDPRGA*LWSG
RIVGEVSGYHSPGDPIQ*FQHGQHQ*QRGIQ*D
NQCPPGKFTG*FFSAPDTTN*QPLRGPRRRRLQV
I**SWFLFPFLHAGGLSVG**PLGVSGWPPGAE
CHSTSHSRAGG*SCVQNQQGWSRATGT*SDCRG
S*SCGFRLRKASEHV*ATSGVFSCSREKGCITKD
SAC*RQGAQGKGAPPATASCAAQWPD*HGGDQA
RRKLFQQVLGGS*AEKHSLPPGHSRI*RDGWAF
QAEVQETADFVHD*GRDPSSSGKGRGAEEAETSL
AEYAEPQDKECPITALQNMLQNCSRENRESQTS
SI
PHH*RPQLAA*LSP*RGCRNPAAQESDADPH
GRL*DTQI*KARENG***CPRGHTG*SKKERTGF
ALGSRDLCQPGGRRQRINFLQPRKRLWCLGDQE
TKKLTTESILMDYLLKCKQTQQSLCRPEAAIYN
DENETKRKSPHQTLDTQESKEKGLFW*LNPSVWF
GANLQWIQKDKTCYKQINIVAAGGTETSLSGR*
RTMVVGPLREQ*GPGWCSLHGTGYFPAPVSHLS
LAASEGVALTPFSPAAIK*MAFLSIFAQKRQL*F
HFSYI*LFLIENNS*SQFIKSIF*DNSSSCHKH
NLFYMRRLRKGKRKTNQMDDVSFRIVSAYNIH*
SAVYENTFSQLCFFIGKLYLVGNNYFYDGMGEYI
HV*NLYALNNLVQDGGGIFRAAIIEKKGELCLG
EVDDKK*KGVYNYFVL*SGP*R*EEE*WIPFGS
IRKETRKKSQEGRERKREGRRKNGNKIRR*EILF
LLSNQCVSG*YKEKYRIEISAGLESATNPKDGV
CVDVCVCVCTPLCVCKMCMFMSKGVCVCVLKFQ
SDRGTWVYR*FLQSCLLASGVE*EFLFYEKGYKG
TELMQYL*Y*VDLTRYLHESQLQSFERFCNLTF
RRVSYLFSYFTFMLSIL*RMPALIFLSFKAI**
GYSIIGCPKFLDEKIFNSGHEKEKKINSLLFFSF
VLKLWFFKKAIINSDLTKNHFCFYIVMS*ALLC
YSNK*QFHKICM*MLTHISFASFIRLVLTLGGD
IYSQMRSRHKVKNGTIY*QGSFKTAKGALT*SHI
LQMAAQIAHGQLAPSLYG*VS*IF*MNSQQNVL
ATGDAKQVRSLLQEIHFIVREVGMETKILRKMR
SVLD*KS*CEMGGLRKEDRLYLRISSQRSQMPGL
RTQR*GGVPKADTGIRTEEAAALHSPRHSGS*D
GWRVG*FYGLPKKCDALHVFSDSWIW*RP*T*Y
RLTSPFFTRGNHPYDLP*SFLFCFEGNHVLHETY
S*QENVQLREKLKRPHYSRNGFRGR*SGL*PQL
IEPEHLLLKE*QSSRAGGSWAMLRVWIRKEILF
LGLSHSHKAVFTVAPTSLNFCYYSYAAFRITAVY
LLAPLTEDPIIIP*KCKLQFTWESQIFSVLLSF
LFIQETLGHRFVHSTVLGSGIPNGPF*LSEDGT
VPWRKVIPA*SIERKRLTKNFASDAQPHPQIAHK
LVNPTSYKMFRFCRC*KPFWKYCILPCL*VFTF
LQS*LTTDMTWLSHPEIMETGSVSGRRPCCVLL
G*HNAVYLPLHTHACCSP*TMTYKPYIDQCPHIY
THTHIYI*SVTRNTKTVLILVSEDK*LNLFFPN
*RMDLIKLCIEKKVA*VLEMVNIFHFS*RTNFL
NFKHSVSCQF*FCVALYPNYFFFVFLFLGEEGKK
AAILCLEIILCIWFSCVC*PLKCYYPALVLE*L
*GIQCKYTVIFSLKSNVC*VFI

Sequence NM_001004065

GCAGATGCGCTGGCCCCAGCCCGGGGCTGCCGCTCGCCTTCCCCCGGAGTCTCCTGGACCCCCGGAGTCTCCTGGACCCCCGGAGCGGGAGGCAGCGGCC
GCGCGGCGCTGGACTGGAGCAGAACCCCAGGACTGCGCCCCCGGGAGCGGGCGCCCAGAGAAGCCTCCCCAGCTTTCTGAGGATGATATCTGGCTAAAAA
GCGAGGGAGACAACTATAGTGCCACCCTCCTGGAGCCTGCTGCCAGCTCTCTTTCCCCAGATCACAAAAACATGGAAATTGAGGTGTCTGTTGCAGAATG
TAAAAGTGTTCCTGGAATCACCTCTACCCCACATCCCATGGACCATCCCTCCGCTTTCTATTCACCCCCGCATAATGGCCTCCTTACTGATCACCACGAA
TCCCTGGATAATGATGTTGCCAGAGAGATCCGCTATCTAGATGAGGTGCTAGAGGCCAACTGCTGTGATTCTGCTGTGGATGGAACGTACAATGGAACAT
CCTCCCCAGAGCCTGGTGCAGTGGTTCTGGTGGGCGGCCTAAGCCCCCCTGTCCACGAGGCGACCCAGCCAGAACCCACTGAAAGAACAGCTAGCCGGCA
GGCACCTCCTCACATCGAGCTCAGTAATAGCAGCCCTGACCCCATGGCAGAGGCAGAAAGAACAAATGGCCATTCCCCCAGCCAGCCTAGAGATGCGCTG
GGGGACAGCCTGCAGGTGCCTGTCAGCCCCAGCTCCACAACCAGCTCACGGTGTTCTTCCCGAGATGGAGAGTTCACTCTCACCACACTGAAAAAGGAGG
CCAAGTTTGAGCTGCGTGCCTTCCATGAGGACAAGAAGCCCTCCAAGCTCTTTGAGGATGACGAGCATGAGAAAGAACAATACTGCATTAGAAAAGTGAG
GCCTTCAGAGGAGATGCTGGAGCTGGAAAAGGAGAGGAGAGAGCTCATCCGCAGCCAGGCCGTCAAGAAGAATCCTGGCATTGCAGCAAAATGGTGGAAT
CCCCCGCAGGAAAAAACCATCGAGGAGCAGCTGGACGAGGAACATCTGGAGTCGCACAAAAAGTACAAGGAGCGCAAAGAGAGAAGGGCACAGCAGGAAC
AGTTGCTGCTGCAGAAGCAGTTACAGCAGCAGCAGCAGCAGCCCCCATCGCAGCTCTGCACAGCCCCTGCCTCTTCTCATGAACGCGCAAGCATGATTGA
CAAAGCAAAGGAGGACATTGTCACAGAGCAGATAGATTTCTCTGCTGCTCGCAAACAATTTCAGCTGATGGAGAATTCCAGGCAAGCGGTGGCCAAGGGC
CAGAGTACACCCAGGCTGTTCTCCATCAAGCCTTTCTACAGGCCTCTGGGGTCAGTCAACTCAGACAAGCCACTGACTAATCCGAGACCACCTTCTGTCG
GGGGACCTCCAGAAGACAGTGGTGCCTCAGCCGCCAAGGGACAGAAATCCCCCGGTGCCCTGGAGACCCCATCGGCAGCAGGAAGCCAGGGCAACACAGC
CTCTCAGGGGAAGGAAGGGCCCTACAGCGAGCCTTCTAAACGTGGGCCCTTATCTAAACTGTGGGCTGAGGATGGAGAATTTACGAGCGCCCGGGCTGTC
CTCACTGTGGTCAAGGATGATGACCATGGGATTTTGGATCAGTTCTCAAGATCTGTCAATGTCTCCTTGACCCAAGAGGAGCTTGACTCTGGTCTGGACG
AATTGTCGGTGAGGTCTCAGGATACCACAGTCCTGGAGACCCTATCCAATGATTTCAGCATGGACAACATCAGTGACAGCGGGGCATCCAATGAGACAAC
CAATGCCCTCCAGGAAAATTCACTGGCTGATTTTTCTCTGCCCCAGACACCACAAACTGACAACCCCTCAGAGGGCCGAGGAGAAGGCGTCTCCAAGTCA
TTTAGTGATCATGGTTTCTATTCCCCTTCCTCCACGCTGGGGGACTCTCCGTTGGTTGATGACCCCTTGGAGTATCAGGCTGGCCTCCTGGTGCAGAATG
CCATTCAACAAGCCATAGCCGAGCAGGTGGATAAAGCTGTGTCCAAAACCAGCAGGGATGGAGCAGAGCAACAGGGACCTGAAGCGACTGTAGAGGAAGC
TGAAGCTGCGGCTTTCGGCTCAGAAAAGCCTCAGAGCATGTTTGAGCCACCTCAGGTGTCTTCTCCTGTTCAAGAGAAAAGGGATGTATTACCAAAGATT
CTGCCTGCTGAAGACAGGGCGCTCAGGGAAAGGGGGCCCCCCCAGCCACTGCCAGCTGTGCAGCCCAGTGGCCCGATTAACATGGAGGAGACCAGGCCCG
AAGGAAGCTATTTCAGCAAGTACTCGGAGGCAGCTGAGCTGAGAAGCACAGCCTCCCTCCTGGCCACTCAAGAATCTGACGTGATGGTTGGGCCTTTCAA
GCTGAGGTCCAGGAAACAGCGGACTTTGTCCATGATTGAGGAAGAGATCCGAGCAGCTCAGGAAAGGGAAGAGGAGCTGAAGAGGCAGAGACAAGTCTTG
CAGAGTACGCAGAGCCCCAGGACAAAGAATGCCCCATCACTGCCCTCCAGAACATGCTACAAAACTGCTCCAGGGAAAATAGAGAAAGTCAAACCTCCTC
CATCC
CCCACCACTGAAGGCCCCAGCTTGCAGCCTGACTTAGCCCCTGAAGAGGCTGCCGGAACCCAGCGGCCCAAGAATCTGATGCAGACCCTCATGGA
AGACTATGAGACACACAAATCTAAAAGGCGCGAGAGAATGGATGATAGTAGTGTCCTCGAGGCCACACGGGTTAATCGAAGAAAGAGCGCACTGGCTTTG
CGCTGGGAAGCAGGGATCTATGCCAACCAGGAGGAAGAAGACAACGAATAAACTTCCTTCAACCCAGGAAGCGTCTTTGGTGCTTGGGAGACCAAGAAAC
CAAGAAATTAACAACTGAAAGCATTTTAATGGACTATTTATTAAAGTGCAAACAAACTCAGCAATCCTTATGTAGACCAGAAGCTGCAATATACAATGAT
GAAAATGAAACGAAAAGGAAGTCCCCCCATCAGACTCTGGACACCCAGGAATCAAAAGAGAAAGGACTTTTTTGGTGACTCAATCCCAGTGTCTGGTTTG
GGGCCAATCTACAATGGATCCAAAAGGACAAAACATGTTACAAGCAAATCAACATAGTTGCTGCAGGCGGAACTGAGACCAGCCTCTCTGGGCGATGAAG
GACAATGGTGGTAGGGCCACTTAGAGAGCAGTAGGGCCCAGGCTGGTGCAGCCTACATGGCACAGGATATTTCCCTGCACCAGTTTCCCACCTGTCACTT
GCAGCATCAGAGGGTGTTGCATTAACTCCATTTTCTCCAGCAGCCATAAAATGAATGGCGTTTCTCTCCATATTTGCCCAGAAGAGGCAGTTATGATTCC
ACTTCTCCTACATTTAATTATTTTTAATTGAGAACAACTCATGATCACAATTCATAAAATCCATATTTTAAGACAATAGTTCTTCATGTCACAAACACAA
TCTATTCTACATGAGGAGGCTGAGAAAGGGGAAGAGAAAAACAAACCAAATGGATGATGTTAGCTTTAGGATCGTGTCTGCTTATAATATTCACTGATCT
GCAGTTTATGAGAACACATTTTCACAGTTATGTTTCTTCATAGGAAAACTATATTTAGTGGGCAACAACTATTTTTATGATGGGATGGGGGAGTATATAC
ACGTATAGAATCTGTACGCGTTGAACAACTTGGTTCAAGATGGTGGGGGCATTTTTAGAGCGGCAATAATTGAAAAAAAAGGCGAACTCTGCCTTGGAGA
GGTAGATGATAAGAAATAAAAAGGTGTTTATAACTATTTTGTATTATAAAGTGGGCCTTAGAGATAGGAAGAAGAATGATGGATTCCTTTTGGATCAATC
AGAAAGGAAACACGAAAGAAAAGTCAGGAAGGTAGAGAGAGAAAAAGGGAGGGAAGGAGAAAGAATGGGAATAAAATAAGGAGGTAAGAGATACTATTTT
TGCTGAGCAACCAGTGTGTTTCAGGATGATACAAAGAAAAATATAGAATAGAAATAAGTGCAGGCTTGGAATCAGCTACAAATCCTAAAGATGGGGTGTG
TGTGGATGTGTGTGTGTGTGTGTGTACACCATTGTGTGTTTGTAAAATGTGTATGTTCATGAGTAAGGGTGTGTGTGTGTGTGTATTAAAATTCCAGAGT
GACCGTGGCACTTGGGTGTACAGGTAATTCCTCCAGAGCTGTTTGCTGGCTTCAGGAGTGGAGTGAGAATTTCTTTTTTATGAAAAGGGATATAAAGGCA
CCGAGCTGATGCAGTATTTGTAATATTAAGTTGACCTAACAAGGTATTTGCATGAGTCACAATTACAAAGTTTTGAGCGGTTTTGTAATTTGACATTTAG
GAGAGTCTCCTATTTATTCTCATACTTTACATTCATGCTTAGTATACTATAGAGGATGCCAGCTTTAATCTTTCTGTCATTTAAAGCAATATGATAAGGG
TATTCAATAATTGGGTGCCCTAAATTTCTGGATGAGAAAATTTTCAATTCTGGCCATGAGAAAGAAAAAAAAATAAACAGCCTTCTTTTTTTTTCCTTTG
TTTTAAAACTGTGGTTTTTTAAAAAAGCAATAATTAACTCAGACCTCACTAAAAATCATTTTTGTTTTTATATTGTTATGTCATAAGCTCTATTATGTTA
TTCTAACAAGTAGCAATTTCACAAAATTTGTATGTAGATGTTAACGCACATTTCCTTTGCTTCTTTTATTAGACTAGTGTTGACTTTGGGGGGGGACATT
TATTCACAAATGAGAAGTAGGCACAAAGTAAAAAATGGAACCATCTACTAACAAGGATCCTTTAAAACTGCCAAGGGAGCTCTAACTTGAAGCCACATCC
TACAGATGGCAGCCCAAATAGCACATGGGCAATTGGCACCATCTTTATATGGTTGAGTCTCCTGAATATTTTGAATGAATTCTCAACAAAATGTGCTAGC
CACTGGGGACGCAAAACAAGTAAGATCCCTGTTGCAAGAAATTCATTTTATAGTGAGGGAGGTTGGCATGGAGACTAAAATTCTCAGGAAAATGAGATCC
GTGTTAGATTAGAAGTCCTGATGTGAAATGGGAGGACTCAGGAAGGAGGATCGTCTTTACCTGAGGATTTCTAGCCAGAGGTCCCAGATGCCTGGGCTGA
GAACCCAGCGATAAGGGGGCGTTCCCAAAGCAGACACAGGGATAAGAACAGAGGAGGCAGCAGCATTGCACAGCCCCAGGCACAGTGGCAGTTAGGATGG
CTGGAGAGTAGGATAGTTCTATGGGTTGCCCAAAAAATGTGATGCGCTTCATGTTTTCTCTGACTCATGGATCTGGTAGAGACCATAGACATGATATAGA
CTAACTTCCCCATTTTTCACAAGAGGAAACCATCCTTATGACTTACCTTAAAGTTTTTTGTTCTGTTTTGAAGGAAACCATGTGCTTCATGAAACCTACA
GTTGACAAGAGAATGTACAGCTAAGAGAAAAGCTTAAGAGGCCACACTATTCGCGGAATGGCTTTAGAGGCAGATGAAGTGGTCTTTGACCACAGTTGAT
TGAACCAGAGCACTTATTGCTTAAAGAATAACAGAGTTCTAGAGCTGGGGGTTCTTGGGCCATGCTCCGTGTGTGGATAAGGAAAGAAATACTGTTTCTG
GGACTCTCCCACAGTCACAAAGCTGTTTTCACTGTGGCCCCTACATCTCTTAACTTTTGCTATTACTCCTATGCTGCCTTCCGGATTACTGCTGTCTATC
TTCTTGCTCCACTCACTGAAGATCCTATTATAATCCCATGAAAATGTAAATTACAGTTTACTTGGGAGAGCCAGATTTTCTCTGTGCTCTTGAGTTTTTT
ATTCATTCAAGAAACCTTGGGCCACCGCTTTGTACATAGCACCGTGCTAGGCTCTGGGATCCCAAATGGACCCTTTTAACTTTCTGAAGATGGGACCGTC
CCCTGGAGGAAAGTCATTCCTGCCTAATCCATCGAGAGAAAGAGGCTTACGAAAAACTTTGCCTCTGATGCTCAGCCCCACCCCCAAATAGCACACAAGC
TTGTTAACCCCACCTCTTACAAAATGTTTAGATTCTGTAGGTGTTAAAAGCCTTTCTGGAAGTATTGCATTCTGCCGTGTTTATAGGTGTTCACTTTCCT
CCAGAGCTGATTAACTACTGACATGACTTGGCTTTCTCATCCAGAAATTATGGAAACAGGGTCTGTCAGTGGCAGGAGGCCGTGCTGTGTTTTACTTGGA
TGACACAATGCAGTTTACTTGCCTCTTCATACCCATGCATGCTGCTCACCCTAGACAATGACATATAAGCCGTATATAGATCAATGTCCACATATATATA
CACACACACATATATATATATAAAGTGTAACAAGGAACACTAAAACAGTGTTGATTCTTGTCTCTGAAGACAAATAATTAAACCTTTTTTTTCCCAACTA
AAGAATGGATTTAATTAAACTATGTATTGAAAAAAAAGTAGCCTAAGTGTTAGAGATGGTGAATATATTCCATTTTAGTTAAAGAACAAATTTCCTGAAT
TTTAAGCATTCAGTGAGCTGCCAATTTTGATTTTGTGTTGCTCTTTACCCAAATTATTTTTTCTTTGTTTTTCTTTTTTTGGGGGAGGAGGGGAAAAAAG
CAGCAATACTGTGTTTGGAAATTATACTCTGTATCTGGTTTTCCTGTGTATGTTAACCACTTAAATGTTATTATCCTGCTTTGGTTTTAGAGTGATTGTG
AGGCATTCAATGCAAGTATACAGTTATTTTCTCATTAAAATCCAATGTGTGTTGAGTTTTTATAAA
  • refseq_PALM2-AKAP2.F2 (forward primer)
  • refseq_PALM2-AKAP2.R2 (reverse primer)
  • Single exon skipping

Frame 0

ADALAPARGCRSPSPGVSWTPGVSWTPGAGGSG
RAALDWSRTPGLRPRERAPREASPAF*G*YLAKK
RGRQL*CHPPGACCQLSFPRSQKHGN*GVCCRM
*KCSWNHLYPTSHGPSLRFLFTPA*WPPY*SPR
IPG**CCQRDPLSR*GARGQLL*FCCGWNVQWNI
LPRAWCSGSGGRPKPPCPRGDPARTH*KNS*PA
GTSSHRAQ**QP*PHGRGRKNKWPFPQPA*RCA
GGQPAGACQPQLHNQLTVFFPRWRVHSHHTEKGG
QV*AACLP*GQEALQAL*G*RA*ERTILH*KSE
AFRGDAGAGKGEERAHPQPGRQEESWHCSKMVE
SPAGKNHRGAAGRGTSGVAQKVQGAQREKGTAGT
VAAAEAVTAAAAAAPIAALHSPCLFS*TRKHD*
QSKGGHCHRADRFLCCSQTISADGEFQASGGQG
PEYTQAVLHQAFLQASGVSQLRQATD*SETTFCR
GTSRRQWCLSRQGTEIPRCPGDPIGSRKPGQHS
LSGEGRALQRAF*TWALI*TVG*GWRIYERPGC
PHCGQG**PWDFGSVLKICQCLLDPRGA*LWSGR
IVGEVSGYHSPGDPIQ*FQHGQHQ*QRGIQ*DN
QCPPGKFTG*FFSAPDTTN*QPLRGPRRRRLQV
I**SWFLFPFLHAGGLSVG**PLGVSGWPPGAEC
HSTSHSRAGG*SCVQNQQGWSRATGT*SDCRGS
*SCGFRLRKASEHV*ATSGVFSCSREKGCITKD
SAC*RQGAQGKGAPPATASCAAQWPD*HGGDQAR
RKLFQQVLGGS*AEKHSLPPGHSRI*RDGWAFQ
AEVQETADFVHD*GRDPSSSGKGRGAEEAETSL
AEYAEPQDKECPITALQNMLQNCSRENRESQTSS
I
PHH*RPQLAA*LSP*RGCRNPAAQESDADPHG
RL*DTQI*KARENG***CPRGHTG*SKKERTGF
ALGSRDLCQPGGRRQRINFLQPRKRLWCLGDQET
KKLTTESILMDYLLKCKQTQQSLCRPEAAIYND
ENETKRKSPHQTLDTQESKEKGLFW*LNPSVWF
GANLQWIQKDKTCYKQINIVAAGGTETSLSGR*R
TMVVGPLREQ*GPGWCSLHGTGYFPAPVSHLSL
AASEGVALTPFSPAAIK*MAFLSIFAQKRQL*F
HFSYI*LFLIENNS*SQFIKSIF*DNSSSCHKHN
LFYMRRLRKGKRKTNQMDDVSFRIVSAYNIH*S
AVYENTFSQLCFFIGKLYLVGNNYFYDGMGEYI
HV*NLYALNNLVQDGGGIFRAAIIEKKGELCLGE
VDDKK*KGVYNYFVL*SGP*R*EEE*WIPFGSI
RKETRKKSQEGRERKREGRRKNGNKIRR*EILF
LLSNQCVSG*YKEKYRIEISAGLESATNPKDGVC
VDVCVCVCTPLCVCKMCMFMSKGVCVCVLKFQS
DRGTWVYR*FLQSCLLASGVE*EFLFYEKGYKG
TELMQYL*Y*VDLTRYLHESQLQSFERFCNLTFR
RVSYLFSYFTFMLSIL*RMPALIFLSFKAI**G
YSIIGCPKFLDEKIFNSGHEKEKKINSLLFFSF
VLKLWFFKKAIINSDLTKNHFCFYIVMS*ALLCY
SNK*QFHKICM*MLTHISFASFIRLVLTLGGDI
YSQMRSRHKVKNGTIY*QGSFKTAKGALT*SHI
LQMAAQIAHGQLAPSLYG*VS*IF*MNSQQNVLA
TGDAKQVRSLLQEIHFIVREVGMETKILRKMRS
VLD*KS*CEMGGLRKEDRLYLRISSQRSQMPGL
RTQR*GGVPKADTGIRTEEAAALHSPRHSGS*DG
WRVG*FYGLPKKCDALHVFSDSWIW*RP*T*YR
LTSPFFTRGNHPYDLP*SFLFCFEGNHVLHETY
S*QENVQLREKLKRPHYSRNGFRGR*SGL*PQLI
EPEHLLLKE*QSSRAGGSWAMLRVWIRKEILFL
GLSHSHKAVFTVAPTSLNFCYYSYAAFRITAVY
LLAPLTEDPIIIP*KCKLQFTWESQIFSVLLSFL
FIQETLGHRFVHSTVLGSGIPNGPF*LSEDGTV
PWRKVIPA*SIERKRLTKNFASDAQPHPQIAHK
LVNPTSYKMFRFCRC*KPFWKYCILPCL*VFTFL
QS*LTTDMTWLSHPEIMETGSVSGRRPCCVLLG
*HNAVYLPLHTHACCSP*TMTYKPYIDQCPHIY
THTHIYI*SVTRNTKTVLILVSEDK*LNLFFPN*
RMDLIKLCIEKKVA*VLEMVNIFHFS*RTNFLN
FKHSVSCQF*FCVALYPNYFFFVFLFLGEEGKK
AAILCLEIILCIWFSCVC*PLKCYYPALVLE*L*
GIQCKYTVIFSLKSNVC*VFI

Frame 1

QMRWPQPGAAARLPPESPGPPESPGPPEREAAA
ARRWTGAEPQDCAPGSGRPEKPPQLSEDDIWLK
SEGDNYSATLLEPAASSLSPDHKNMEIEVSVAEC
KSVPGITSTPHPMDHPSAFYSPPHNGLLTDHHE
SLDNDVAREIRYLDEVLEANCCDSAVDGTYNGT
SSPEPGAVVLVGGLSPPVHEATQPEPTERTASRQ
APPHIELSNSSPDPMAEAERTNGHSPSQPRDAL
GDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKE
AKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKVR
PSEEMLELEKERRELIRSQAVKKNPGIAAKWWN
PPQEKTIEEQLDEEHLESHKKYKERKERRAQQE
QLLLQKQLQQQQQQPPSQLCTAPASSHERASMID
KAKEDIVTEQIDFSAARKQFQLMENSRQAVAKG
QSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSV
GGPPEDSGASAAKGQKSPGALETPSAAGSQGNTA
SQGKEGPYSEPSKRGPLSKLWAEDGEFTSARAV
LTVVKDDDHGILDQFSRSVNVSLTQEELDSGLD
ELSVRSQDTTVLETLSNDFSMDNISDSGASNETT
NALQENSLADFSLPQTPQTDNPSEGRGEGVSKS
FSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQN
AIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEEA
EAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPKI
LPAEDRALRERGPPQPLPAVQPSGPINMEETRP
EGSYFSKYSEAAELRSTASLLATQESDVMVGPFK
LRSRKQRTLSMIEEEIRAAQEREEELKRQRQVL
QSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPP
PS
PTTEGPSLQPDLAPEEAAGTQRPKNLMQTLME
DYETHKSKRRERMDDSSVLEATRVNRRKSALAL
RWEAGIYANQEEEDNE*TSFNPGSVFGAWETKK
PRN*QLKAF*WTIY*SANKLSNPYVDQKLQYTMM
KMKRKGSPPIRLWTPRNQKRKDFFGDSIPVSGL
GPIYNGSKRTKHVTSKST*LLQAELRPASLGDE
GQWW*GHLESSRAQAGAAYMAQDISLHQFPTCHL
QHQRVLH*LHFLQQP*NEWRFSPYLPRRGSYDS
TSPTFNYF*LRTTHDHNS*NPYFKTIVLHVTNT
IYST*GG*ERGREKQTKWMMLALGSCLLIIFTDL
QFMRTHFHSYVSS*ENYI*WATTIFMMGWGSIY
TYRICTR*TTWFKMVGAFLERQ*LKKKANSALE
R*MIRNKKVFITILYYKVGLRDRKKNDGFLLDQS
ERKHERKVRKVEREKGREGERMGIK*GGKRYYF
C*ATSVFQDDTKKNIE*K*VQAWNQLQILKMGC
VWMCVCVCVHHCVFVKCVCS*VRVCVCVY*NSRV
TVALGCTGNSSRAVCWLQEWSENFFFMKRDIKA
PS*CSICNIKLT*QGICMSHNYKVLSGFVI*HL
GESPIYSHTLHSCLVYYRGCQL*SFCHLKQYDKG
IQ*LGALNFWMRKFSILAMRKKKK*TAFFFFPL
F*NCGFLKKQ*LTQTSLKIIFVFILLCHKLYYV
ILTSSNFTKFVCRC*RTFPLLLLLD*C*LWGGTF
IHK*EVGTK*KMEPSTNKDPLKLPREL*LEATS
YRWQPK*HMGNWHHLYMVESPEYFE*ILNKMC*
PLGTQNK*DPCCKKFIL**GRLAWRLKFSGK*DP
C*IRSPDVKWEDSGRRIVFT*GFLARGPRCLG*
EPSDKGAFPKQTQG*EQRRQQHCTAPGTVAVRM
AGE*DSSMGCPKNVMRFMFSLTHGSGRDHRHDID
*LPHFSQEETILMTYLKVFCSVLKETMCFMKPT
VDKRMYS*EKSLRGHTIRGMALEADEVVFDHS*
LNQSTYCLKNNRVLELGVLGPCSVCG*GKKYCFW
DSPTVTKLFSLWPLHLLTFAITPMLPSGLLLSI
FLLHSLKILL*SHENVNYSLLGRARFSLCS*VF
YSFKKPWATALYIAPC*ALGSQMDPFNFLKMGPS
PGGKSFLPNPSRERGLRKTLPLMLSPTPK*HTS
LLTPPLTKCLDSVGVKSLSGSIAFCRVYRCSLS
SRAD*LLT*LGFLIQKLWKQGLSVAGGRAVFYLD
DTMQFTCLFIPMHAAHPRQ*HISRI*INVHIYI
HTHIYIYKV*QGTLKQC*FLSLKTNN*TFFFPT
KEWI*LNYVLKKK*PKC*RW*IYSILVKEQIS*I
LSIQ*AANFDFVLLFTQIIFSLFFFFWGRRGKK
QQYCVWKLYSVSGFPVYVNHLNVIILLWF*SDC
EAFNASIQLFSH*NPMCVEFL*

Frame 2

RCAGPSPGLPLAFPRSLLDPRSLLDPRSGRQRP
RGAGLEQNPRTAPPGAGAQRSLPSFLRMISG*K
ARETTIVPPSWSLLPALFPQITKTWKLRCLLQN
VKVFLESPLPHIPWTIPPLSIHPRIMASLLITTN
PWIMMLPERSAI*MRC*RPTAVILLWMERTMEH
PPQSLVQWFWWAA*APLSTRRPSQNPLKEQLAG
RHLLTSSSVIAALTPWQRQKEQMAIPPASLEMRW
GTACRCLSAPAPQPAHGVLPEMESSLSPH*KRR
PSLSCVPSMRTRSPPSSLRMTSMRKNNTALEK*
GLQRRCWSWKRRGESSSAARPSRRILALQQNGGI
PRRKKPSRSSWTRNIWSRTKSTRSAKREGHSRN
SCCCRSSYSSSSSSPHRSSAQPLPLLMNAQA*L
TKQRRTLSQSR*ISLLLANNFS*WRIPGKRWPRA
RVHPGCSPSSLSTGLWGQSTQTSH*LIRDHLLS
GDLQKTVVPQPPRDRNPPVPWRPHRQQEARATQ
PLRGRKGPTASLLNVGPYLNCGLRMENLRAPGLS
SLWSRMMTMGFWISSQDLSMSP*PKRSLTLVWT
NCR*GLRIPQSWRPYPMISAWTTSVTAGHPMRQ
PMPSRKIHWLIFLCPRHHKLTTPQRAEEKASPSH
LVIMVSIPLPPRWGTLRWLMTPWSIRLASWCRM
PFNKP*PSRWIKLCPKPAGMEQSNRDLKRL*RK
LKLRLSAQKSLRACLSHLRCLLLFKRKGMYYQRF
CLLKTGRSGKGGPPSHCQLCSPVARLTWRRPGP
KEAISASTRRQLS*EAQPPSWPLKNLT*WLGLS
S*GPGNSGLCP*LRKRSEQLRKGKRS*RGRDKSC
RVRRAPGQRMPHHCPPEHATKLLQGK*RKSNLL
HP
PPLKAPACSLT*PLKRLPEPSGPRI*CRPSW
KTMRHTNLKGAREWMIVVSSRPHGLIEERAHWLC
AGKQGSMPTRRKKTTNKLPSTQEASLVLGRPRN
QEINN*KHFNGLFIKVQTNSAILM*TRSCNIQ*
*K*NEKEVPPSDSGHPGIKRERTFLVTQSQCLVW
GQSTMDPKGQNMLQANQHSCCRRN*DQPLWAMK
DNGGRAT*RAVGPRLVQPTWHRIFPCTSFPPVT
CSIRGCCINSIFSSSHKMNGVSLHICPEEAVMIP
LLLHLIIFN*EQLMITIHKIHILRQ*FFMSQTQ
SILHEEAEKGEEKNKPNG*C*L*DRVCL*YSLI
CSL*EHIFTVMFLHRKTIFSGQQLFL*WDGGVYT
RIESVRVEQLGSRWWGHF*SGNN*KKRRTLPWR
GR**EIKRCL*LFCIIKWALEIGRRMMDSFWIN
QKGNTKEKSGR*REKKGGKEKEWE*NKEVRDTIF
AEQPVCFRMIQRKI*NRNKCRLGISYKS*RWGV
CGCVCVCVYTIVCL*NVYVHE*GCVCVCIKIPE
*PWHLGVQVIPPELFAGFRSGVRISFL*KGI*RH
RADAVFVILS*PNKVFA*VTITKF*AVL*FDI*
ESLLFILILYIHA*YTIEDASFNLSVI*SNMIR
VFNNWVP*ISG*ENFQFWP*ERKKNKQPSFFFLC
FKTVVF*KSNN*LRPH*KSFLFLYCYVISSIML
F*QVAISQNLYVDVNAHFLCFFY*TSVDFGGGH
LFTNEK*AQSKKWNHLLTRIL*NCQGSSNLKPHP
TDGSPNSTWAIGTIFIWLSLLNILNEFSTKCAS
HWGRKTSKIPVARNSFYSEGGWHGD*NSQENEI
RVRLEVLM*NGRTQEGGSSLPEDF*PEVPDAWAE
NPAIRGRSQSRHRDKNRGGSSIAQPQAQWQLGW
LESRIVLWVAQKM*CASCFL*LMDLVETIDMI*
TNFPIFHKRKPSL*LTLKFFVLF*RKPCAS*NLQ
LTRECTAKRKA*EATLFAEWL*RQMKWSLTTVD
*TRALIA*RITEF*SWGFLGHAPCVDKERNTVS
GTLPQSQSCFHCGPYIS*LLLLLLCCLPDYCCLS
SCSTH*RSYYNPMKM*ITVYLGEPDFLCALEFF
IHSRNLGPPLCT*HRARLWDPKWTLLTF*RWDR
PLEESHSCLIHREKEAYEKLCL*CSAPPPNSTQA
C*PHLLQNV*IL*VLKAFLEVLHSAVFIGVHFP
PELINY*HDLAFSSRNYGNRVCQWQEAVLCFTW
MTQCSLLASSYPCMLLTLDNDI*AVYRSMSTYIY
THTYIYIKCNKEH*NSVDSCL*RQIIKPFFSQL
KNGFN*TMY*KKSSLSVRDGEYIPF*LKNKFPE
F*AFSELPILILCCSLPKLFFLCFSFFGGGGEKS
SNTVFGNYTLYLVFLCMLTT*MLLSCFGFRVIV
RHSMQVYSYFLIKIQCVLSFYK

Sequence NM_007203

CCCGGGCGAGCCCGCCGTGCGCACAGCTCTGCCCGCCGCCCCTGGAGCGGATCCCCAGCCGTCCCTGGGCGTTCTCCCGGGTTCTAGCAAAGCCCCCCGG
GGTGCCCATCAGTTTCCTTGGGTGACTACAGCGTGTGTTTTTTCTTTCCTCTTTCCCCTGCCTGTGTGCCCTTCTCCAGGATGGCAGAGGCGGAATTGCA
CAAGGAAAGGCTGCAAGCCATAGCAGAAAAAAGAAAGAGGCAGACTGAAATAGAAGGCAAGCGACAACAGCTTGACGAGCAGATACTTCTGCTGCAGCAT
TCCAAGTCCAAAGTGCTTCGGGAGAAATGGCTGCTGCAGGGCATACCCGCTGGAACTGCCGAAGAGGAGGAAGCCAGGAGGCGGCAGTCTGAAGAGGATG
AGTTCAGAGTCAAGCAACTTGAAGATAACATTCAGAGGCTGGAGCAAGAAATACAAACGCTAGAAAGTGAAGAGTCCCAGATATCTGCCAAAGAGCAAAT
CATCCTAGAGAAACTGAAGGAAACAGAAAAATCCTTCAAGGACTTTCAGAAGGGTTTCTCCAGTACGGATGGAGATGCAGTAAATTACATTTCCTCCCAG
CTTCCCGACCTGCCAATCCTCTGTTCACGAACAGCAGAACCATCACCTGGGCAGGACGGGACCAGCAGAGCGGCTGGAGTCGGGTGGGAGAATGTGCTGC
TAAAGGAAGGTGAGTCAGCCTCGAACGCCACAGAAACATCCGGCCCAGACATGACTATCAAGAAGCCTCCCCAGCTTTCTGAGGATGATATCTGGCTAAA
AAGCGAGGGAGACAACTATAGTGCCACCCTCCTGGAGCCTGCTGCCAGCTCTCTTTCCCCAGATCACAAAAACATGGAAATTGAGGTGTCTGTTGCAGAA
TGTAAAAGTGTTCCTGGAATCACCTCTACCCCACATCCCATGGACCATCCCTCCGCTTTCTATTCACCCCCGCATAATGGCCTCCTTACTGATCACCACG
AATCCCTGGATAATGATGTTGCCAGAGAGATCCGCTATCTAGATGAGGTGCTAGAGGCCAACTGCTGTGATTCTGCTGTGGATGGAACGTACAATGGAAC
ATCCTCCCCAGAGCCTGGTGCAGTGGTTCTGGTGGGCGGCCTAAGCCCCCCTGTCCACGAGGCGACCCAGCCAGAACCCACTGAAAGAACAGCTAGCCGG
CAGGCACCTCCTCACATCGAGCTCAGTAATAGCAGCCCTGACCCCATGGCAGAGGCAGAAAGAACAAATGGCCATTCCCCCAGCCAGCCTAGAGATGCGC
TGGGGGACAGCCTGCAGGTGCCTGTCAGCCCCAGCTCCACAACCAGCTCACGGTGTTCTTCCCGAGATGGAGAGTTCACTCTCACCACACTGAAAAAGGA
GGCCAAGTTTGAGCTGCGTGCCTTCCATGAGGACAAGAAGCCCTCCAAGCTCTTTGAGGATGACGAGCATGAGAAAGAACAATACTGCATTAGAAAAGTG
AGGCCTTCAGAGGAGATGCTGGAGCTGGAAAAGGAGAGGAGAGAGCTCATCCGCAGCCAGGCCGTCAAGAAGAATCCTGGCATTGCAGCAAAATGGTGGA
ATCCCCCGCAGGAAAAAACCATCGAGGAGCAGCTGGACGAGGAACATCTGGAGTCGCACAAAAAGTACAAGGAGCGCAAAGAGAGAAGGGCACAGCAGGA
ACAGTTGCTGCTGCAGAAGCAGTTACAGCAGCAGCAGCAGCAGCCCCCATCGCAGCTCTGCACAGCCCCTGCCTCTTCTCATGAACGCGCAAGCATGATT
GACAAAGCAAAGGAGGACATTGTCACAGAGCAGATAGATTTCTCTGCTGCTCGCAAACAATTTCAGCTGATGGAGAATTCCAGGCAAGCGGTGGCCAAGG
GCCAGAGTACACCCAGGCTGTTCTCCATCAAGCCTTTCTACAGGCCTCTGGGGTCAGTCAACTCAGACAAGCCACTGACTAATCCGAGACCACCTTCTGT
CGGGGGACCTCCAGAAGACAGTGGTGCCTCAGCCGCCAAGGGACAGAAATCCCCCGGTGCCCTGGAGACCCCATCGGCAGCAGGAAGCCAGGGCAACACA
GCCTCTCAGGGGAAGGAAGGGCCCTACAGCGAGCCTTCTAAACGTGGGCCCTTATCTAAACTGTGGGCTGAGGATGGAGAATTTACGAGCGCCCGGGCTG
TCCTCACTGTGGTCAAGGATGATGACCATGGGATTTTGGATCAGTTCTCAAGATCTGTCAATGTCTCCTTGACCCAAGAGGAGCTTGACTCTGGTCTGGA
CGAATTGTCGGTGAGGTCTCAGGATACCACAGTCCTGGAGACCCTATCCAATGATTTCAGCATGGACAACATCAGTGACAGCGGGGCATCCAATGAGACA
ACCAATGCCCTCCAGGAAAATTCACTGGCTGATTTTTCTCTGCCCCAGACACCACAAACTGACAACCCCTCAGAGGGCCGAGGAGAAGGCGTCTCCAAGT
CATTTAGTGATCATGGTTTCTATTCCCCTTCCTCCACGCTGGGGGACTCTCCGTTGGTTGATGACCCCTTGGAGTATCAGGCTGGCCTCCTGGTGCAGAA
TGCCATTCAACAAGCCATAGCCGAGCAGGTGGATAAAGCTGTGTCCAAAACCAGCAGGGATGGAGCAGAGCAACAGGGACCTGAAGCGACTGTAGAGGAA
GCTGAAGCTGCGGCTTTCGGCTCAGAAAAGCCTCAGAGCATGTTTGAGCCACCTCAGGTGTCTTCTCCTGTTCAAGAGAAAAGGGATGTATTACCAAAGA
TTCTGCCTGCTGAAGACAGGGCGCTCAGGGAAAGGGGGCCCCCCCAGCCACTGCCAGCTGTGCAGCCCAGTGGCCCGATTAACATGGAGGAGACCAGGCC
CGAAGGAAGCTATTTCAGCAAGTACTCGGAGGCAGCTGAGCTGAGAAGCACAGCCTCCCTCCTGGCCACTCAAGAATCTGACGTGATGGTTGGGCCTTTC
AAGCTGAGGTCCAGGAAACAGCGGACTTTGTCCATGATTGAGGAAGAGATCCGAGCAGCTCAGGAAAGGGAAGAGGAGCTGAAGAGGCAGAGACAAGTCT
TGCAGAGTACGCAGAGCCCCAGGACAAAGAATGCCCCATCACTGCCCTCCAGAACATGCTACAAAACTGCTCCAGGGAAAATAGAGAAAGTCAAACCTCC
TCCATCC
CCCACCACTGAAGGCCCCAGCTTGCAGCCTGACTTAGCCCCTGAAGAGGCTGCCGGAACCCAGCGGCCCAAGAATCTGATGCAGACCCTCATG
GAAGACTATGAGACACACAAATCTAAAAGGCGCGAGAGAATGGATGATAGTAGTTACACTTCTAAGTTACTGTCTTGCAAGGTGACTTCCGAGGTCCTCG
AGGCCACACGGGTTAATCGAAGAAAGAGCGCACTGGCTTTGCGCTGGGAAGCAGGGATCTATGCCAACCAGGAGGAAGAAGACAACGAATAAACTTCCTT
CAACCCAGGAAGCGTCTTTGGTGCTTGGGAGACCAAGAAACCAAGAAATTAACAACTGAAAGCATTTTAATGGACTATTTATTAAAGTGCAAACAAACTC
AGCAATCCTTATGTAGACCAGAAGCTGCAATATACAATGATGAAAATGAAACGAAAAGGAAGTCCCCCCATCAGACTCTGGACACCCAGGAATCAAAAGA
GAAAGGACTTTTTTGGTGACTCAATCCCAGTGTCTGGTTTGGGGCCAATCTACAATGGATCCAAAAGGACAAAACATGTTACAAGCAAATCAACATAGTT
GCTGCAGGCGGAACTGAGACCAGCCTCTCTGGGCGATGAAGGACAATGGTGGTAGGGCCACTTAGAGAGCAGTAGGGCCCAGGCTGGTGCAGCCTACATG
GCACAGGATATTTCCCTGCACCAGTTTCCCACCTGTCACTTGCAGCATCAGAGGGTGTTGCATTAACTCCATTTTCTCCAGCAGCCATAAAATGAATGGC
GTTTCTCTCCATATTTGCCCAGAAGAGGCAGTTATGATTCCACTTCTCCTACATTTAATTATTTTTAATTGAGAACAACTCATGATCACAATTCATAAAA
TCCATATTTTAAGACAATAGTTCTTCATGTCACAAACACAATCTATTCTACATGAGGAGGCTGAGAAAGGGGAAGAGAAAAACAAACCAAATGGATGATG
TTAGCTTTAGGATCGTGTCTGCTTATAATATTCACTGATCTGCAGTTTATGAGAACACATTTTCACAGTTATGTTTCTTCATAGGAAAACTATATTTAGT
GGGCAACAACTATTTTTATGATGGGATGGGGGAGTATATACACGTATAGAATCTGTACGCGTTGAACAACTTGGTTCAAGATGGTGGGGGCATTTTTAGA
GCGGCAATAATTGAAAAAAAAGGCGAACTCTGCCTTGGAGAGGTAGATGATAAGAAATAAAAAGGTGTTTATAACTATTTTGTATTATAAAGTGGGCCTT
AGAGATAGGAAGAAGAATGATGGATTCCTTTTGGATCAATCAGAAAGGAAACACGAAAGAAAAGTCAGGAAGGTAGAGAGAGAAAAAGGGAGGGAAGGAG
AAAGAATGGGAATAAAATAAGGAGGTAAGAGATACTATTTTTGCTGAGCAACCAGTGTGTTTCAGGATGATACAAAGAAAAATATAGAATAGAAATAAGT
GCAGGCTTGGAATCAGCTACAAATCCTAAAGATGGGGTGTGTGTGGATGTGTGTGTGTGTGTGTGTACACCATTGTGTGTTTGTAAAATGTGTATGTTCA
TGAGTAAGGGTGTGTGTGTGTGTGTATTAAAATTCCAGAGTGACCGTGGCACTTGGGTGTACAGGTAATTCCTCCAGAGCTGTTTGCTGGCTTCAGGAGT
GGAGTGAGAATTTCTTTTTTATGAAAAGGGATATAAAGGCACCGAGCTGATGCAGTATTTGTAATATTAAGTTGACCTAACAAGGTATTTGCATGAGTCA
CAATTACAAAGTTTTGAGCGGTTTTGTAATTTGACATTTAGGAGAGTCTCCTATTTATTCTCATACTTTACATTCATGCTTAGTATACTATAGAGGATGC
CAGCTTTAATCTTTCTGTCATTTAAAGCAATATGATAAGGGTATTCAATAATTGGGTGCCCTAAATTTCTGGATGAGAAAATTTTCAATTCTGGCCATGA
GAAAGAAAAAAAAATAAACAGCCTTCTTTTTTTTTCCTTTGTTTTAAAACTGTGGTTTTTTAAAAAAGCAATAATTAACTCAGACCTCACTAAAAATCAT
TTTTGTTTTTATATTGTTATGTCATAAGCTCTATTATGTTATTCTAACAAGTAGCAATTTCACAAAATTTGTATGTAGATGTTAACGCACATTTCCTTTG
CTTCTTTTATTAGACTAGTGTTGACTTTGGGGGGGGACATTTATTCACAAATGAGAAGTAGGCACAAAGTAAAAAATGGAACCATCTACTAACAAGGATC
CTTTAAAACTGCCAAGGGAGCTCTAACTTGAAGCCACATCCTACAGATGGCAGCCCAAATAGCACATGGGCAATTGGCACCATCTTTATATGGTTGAGTC
TCCTGAATATTTTGAATGAATTCTCAACAAAATGTGCTAGCCACTGGGGACGCAAAACAAGTAAGATCCCTGTTGCAAGAAATTCATTTTATAGTGAGGG
AGGTTGGCATGGAGACTAAAATTCTCAGGAAAATGAGATCCGTGTTAGATTAGAAGTCCTGATGTGAAATGGGAGGACTCAGGAAGGAGGATCGTCTTTA
CCTGAGGATTTCTAGCCAGAGGTCCCAGATGCCTGGGCTGAGAACCCAGCGATAAGGGGGCGTTCCCAAAGCAGACACAGGGATAAGAACAGAGGAGGCA
GCAGCATTGCACAGCCCCAGGCACAGTGGCAGTTAGGATGGCTGGAGAGTAGGATAGTTCTATGGGTTGCCCAAAAAATGTGATGCGCTTCATGTTTTCT
CTGACTCATGGATCTGGTAGAGACCATAGACATGATATAGACTAACTTCCCCATTTTTCACAAGAGGAAACCATCCTTATGACTTACCTTAAAGTTTTTT
GTTCTGTTTTGAAGGAAACCATGTGCTTCATGAAACCTACAGTTGACAAGAGAATGTACAGCTAAGAGAAAAGCTTAAGAGGCCACACTATTCGCGGAAT
GGCTTTAGAGGCAGATGAAGTGGTCTTTGACCACAGTTGATTGAACCAGAGCACTTATTGCTTAAAGAATAACAGAGTTCTAGAGCTGGGGGTTCTTGGG
CCATGCTCCGTGTGTGGATAAGGAAAGAAATACTGTTTCTGGGACTCTCCCACAGTCACAAAGCTGTTTTCACTGTGGCCCCTACATCTCTTAACTTTTG
CTATTACTCCTATGCTGCCTTCCGGATTACTGCTGTCTATCTTCTTGCTCCACTCACTGAAGATCCTATTATAATCCCATGAAAATGTAAATTACAGTTT
ACTTGGGAGAGCCAGATTTTCTCTGTGCTCTTGAGTTTTTTATTCATTCAAGAAACCTTGGGCCACCGCTTTGTACATAGCACCGTGCTAGGCTCTGGGA
TCCCAAATGGACCCTTTTAACTTTCTGAAGATGGGACCGTCCCCTGGAGGAAAGTCATTCCTGCCTAATCCATCGAGAGAAAGAGGCTTACGAAAAACTT
TGCCTCTGATGCTCAGCCCCACCCCCAAATAGCACACAAGCTTGTTAACCCCACCTCTTACAAAATGTTTAGATTCTGTAGGTGTTAAAAGCCTTTCTGG
AAGTATTGCATTCTGCCGTGTTTATAGGTGTTCACTTTCCTCCAGAGCTGATTAACTACTGACATGACTTGGCTTTCTCATCCAGAAATTATGGAAACAG
GGTCTGTCAGTGGCAGGAGGCCGTGCTGTGTTTTACTTGGATGACACAATGCAGTTTACTTGCCTCTTCATACCCATGCATGCTGCTCACCCTAGACAAT
GACATATAAGCCGTATATAGATCAATGTCCACATATATATACACACACACATATATATATATAAAGTGTAACAAGGAACACTAAAACAGTGTTGATTCTT
GTCTCTGAAGACAAATAATTAAACCTTTTTTTTCCCAACTAAAGAATGGATTTAATTAAACTATGTATTGAAAAAAAAGTAGCCTAAGTGTTAGAGATGG
TGAATATATTCCATTTTAGTTAAAGAACAAATTTCCTGAATTTTAAGCATTCAGTGAGCTGCCAATTTTGATTTTGTGTTGCTCTTTACCCAAATTATTT
TTTCTTTGTTTTTCTTTTTTTGGGGGAGGAGGGGAAAAAAGCAGCAATACTGTGTTTGGAAATTATACTCTGTATCTGGTTTTCCTGTGTATGTTAACCA
CTTAAATGTTATTATCCTGCTTTGGTTTTAGAGTGATTGTGAGGCATTCAATGCAAGTATACAGTTATTTTCTCATTAAAATCCAATGTGTGTTGAGTTT
TTATAAA
  • refseq_PALM2-AKAP2.F2 (forward primer)
  • refseq_PALM2-AKAP2.R2 (reverse primer)
  • Single exon skipping

Frame 0

PGRARRAHSSARRPWSGSPAVPGRSPGF*QSPP
GCPSVSLGDYSVCFFFPLSPACVPFSRMAEAELH
KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQH
SKSKVLREKWLLQGIPAGTAEEEEARRRQSEED
EFRVKQLEDNIQRLEQEIQTLESEESQISAKEQI
ILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQ
LPDLPILCSRTAEPSPGQDGTSRAAGVGWENVL
LKEGESASNATETSGPDMTIKKPPQLSEDDIWLK
SEGDNYSATLLEPAASSLSPDHKNMEIEVSVAE
CKSVPGITSTPHPMDHPSAFYSPPHNGLLTDHH
ESLDNDVAREIRYLDEVLEANCCDSAVDGTYNGT
SSPEPGAVVLVGGLSPPVHEATQPEPTERTASR
QAPPHIELSNSSPDPMAEAERTNGHSPSQPRDA
LGDSLQVPVSPSSTTSSRCSSRDGEFTLTTLKKE
AKFELRAFHEDKKPSKLFEDDEHEKEQYCIRKV
RPSEEMLELEKERRELIRSQAVKKNPGIAAKWW
NPPQEKTIEEQLDEEHLESHKKYKERKERRAQQE
QLLLQKQLQQQQQQPPSQLCTAPASSHERASMI
DKAKEDIVTEQIDFSAARKQFQLMENSRQAVAK
GQSTPRLFSIKPFYRPLGSVNSDKPLTNPRPPSV
GGPPEDSGASAAKGQKSPGALETPSAAGSQGNT
ASQGKEGPYSEPSKRGPLSKLWAEDGEFTSARA
VLTVVKDDDHGILDQFSRSVNVSLTQEELDSGLD
ELSVRSQDTTVLETLSNDFSMDNISDSGASNET
TNALQENSLADFSLPQTPQTDNPSEGRGEGVSK
SFSDHGFYSPSSTLGDSPLVDDPLEYQAGLLVQN
AIQQAIAEQVDKAVSKTSRDGAEQQGPEATVEE
AEAAAFGSEKPQSMFEPPQVSSPVQEKRDVLPK
ILPAEDRALRERGPPQPLPAVQPSGPINMEETRP
EGSYFSKYSEAAELRSTASLLATQESDVMVGPF
KLRSRKQRTLSMIEEEIRAAQEREEELKRQRQV
LQSTQSPRTKNAPSLPSRTCYKTAPGKIEKVKPP
PS
PTTEGPSLQPDLAPEEAAGTQRPKNLMQTLM
EDYETHKSKRRERMDDSSYTSKLLSCKVTSEVL
EATRVNRRKSALALRWEAGIYANQEEEDNE*TSF
NPGSVFGAWETKKPRN*QLKAF*WTIY*SANKL
SNPYVDQKLQYTMMKMKRKGSPPIRLWTPRNQK
RKDFFGDSIPVSGLGPIYNGSKRTKHVTSKST*L
LQAELRPASLGDEGQWW*GHLESSRAQAGAAYM
AQDISLHQFPTCHLQHQRVLH*LHFLQQP*NEW
RFSPYLPRRGSYDSTSPTFNYF*LRTTHDHNS*N
PYFKTIVLHVTNTIYST*GG*ERGREKQTKWMM
LALGSCLLIIFTDLQFMRTHFHSYVSS*ENYI*
WATTIFMMGWGSIYTYRICTR*TTWFKMVGAFLE
RQ*LKKKANSALER*MIRNKKVFITILYYKVGL
RDRKKNDGFLLDQSERKHERKVRKVEREKGREG
ERMGIK*GGKRYYFC*ATSVFQDDTKKNIE*K*V
QAWNQLQILKMGCVWMCVCVCVHHCVFVKCVCS
*VRVCVCVY*NSRVTVALGCTGNSSRAVCWLQE
WSENFFFMKRDIKAPS*CSICNIKLT*QGICMSH
NYKVLSGFVI*HLGESPIYSHTLHSCLVYYRGC
QL*SFCHLKQYDKGIQ*LGALNFWMRKFSILAM
RKKKK*TAFFFFPLF*NCGFLKKQ*LTQTSLKII
FVFILLCHKLYYVILTSSNFTKFVCRC*RTFPL
LLLLD*C*LWGGTFIHK*EVGTK*KMEPSTNKD
PLKLPREL*LEATSYRWQPK*HMGNWHHLYMVES
PEYFE*ILNKMC*PLGTQNK*DPCCKKFIL**G
RLAWRLKFSGK*DPC*IRSPDVKWEDSGRRIVF
T*GFLARGPRCLG*EPSDKGAFPKQTQG*EQRRQ
QHCTAPGTVAVRMAGE*DSSMGCPKNVMRFMFS
LTHGSGRDHRHDID*LPHFSQEETILMTYLKVF
CSVLKETMCFMKPTVDKRMYS*EKSLRGHTIRGM
ALEADEVVFDHS*LNQSTYCLKNNRVLELGVLG
PCSVCG*GKKYCFWDSPTVTKLFSLWPLHLLTF
AITPMLPSGLLLSIFLLHSLKILL*SHENVNYSL
LGRARFSLCS*VFYSFKKPWATALYIAPC*ALG
SQMDPFNFLKMGPSPGGKSFLPNPSRERGLRKT
LPLMLSPTPK*HTSLLTPPLTKCLDSVGVKSLSG
SIAFCRVYRCSLSSRAD*LLT*LGFLIQKLWKQ
GLSVAGGRAVFYLDDTMQFTCLFIPMHAAHPRQ
*HISRI*INVHIYIHTHIYIYKV*QGTLKQC*FL
SLKTNN*TFFFPTKEWI*LNYVLKKK*PKC*RW
*IYSILVKEQIS*ILSIQ*AANFDFVLLFTQII
FSLFFFFWGRRGKKQQYCVWKLYSVSGFPVYVNH
LNVIILLWF*SDCEAFNASIQLFSH*NPMCVEF
L*

Frame 1

PGEPAVRTALPAAPGADPQPSLGVLPGSSKAPR
GAHQFPWVTTACVFSFLFPLPVCPSPGWQRRNC
TRKGCKP*QKKERGRLK*KASDNSLTSRYFCCSI
PSPKCFGRNGCCRAYPLELPKRRKPGGGSLKRM
SSESSNLKITFRGWSKKYKR*KVKSPRYLPKSK
SS*RN*RKQKNPSRTFRRVSPVRMEMQ*ITFPPS
FPTCQSSVHEQQNHHLGRTGPAERLESGGRMCC
*RKVSQPRTPQKHPAQT*LSRSLPSFLRMISG*
KARETTIVPPSWSLLPALFPQITKTWKLRCLLQN
VKVFLESPLPHIPWTIPPLSIHPRIMASLLITT
NPWIMMLPERSAI*MRC*RPTAVILLWMERTME
HPPQSLVQWFWWAA*APLSTRRPSQNPLKEQLAG
RHLLTSSSVIAALTPWQRQKEQMAIPPASLEMR
WGTACRCLSAPAPQPAHGVLPEMESSLSPH*KR
RPSLSCVPSMRTRSPPSSLRMTSMRKNNTALEK*
GLQRRCWSWKRRGESSSAARPSRRILALQQNGG
IPRRKKPSRSSWTRNIWSRTKSTRSAKREGHSR
NSCCCRSSYSSSSSSPHRSSAQPLPLLMNAQA*L
TKQRRTLSQSR*ISLLLANNFS*WRIPGKRWPR
ARVHPGCSPSSLSTGLWGQSTQTSH*LIRDHLL
SGDLQKTVVPQPPRDRNPPVPWRPHRQQEARATQ
PLRGRKGPTASLLNVGPYLNCGLRMENLRAPGL
SSLWSRMMTMGFWISSQDLSMSP*PKRSLTLVW
TNCR*GLRIPQSWRPYPMISAWTTSVTAGHPMRQ
PMPSRKIHWLIFLCPRHHKLTTPQRAEEKASPS
HLVIMVSIPLPPRWGTLRWLMTPWSIRLASWCR
MPFNKP*PSRWIKLCPKPAGMEQSNRDLKRL*RK
LKLRLSAQKSLRACLSHLRCLLLFKRKGMYYQR
FCLLKTGRSGKGGPPSHCQLCSPVARLTWRRPG
PKEAISASTRRQLS*EAQPPSWPLKNLT*WLGLS
S*GPGNSGLCP*LRKRSEQLRKGKRS*RGRDKS
CRVRRAPGQRMPHHCPPEHATKLLQGK*RKSNL
LHP
PPLKAPACSLT*PLKRLPEPSGPRI*CRPSW
KTMRHTNLKGAREWMIVVTLLSYCLAR*LPRSS
RPHGLIEERAHWLCAGKQGSMPTRRKKTTNKLP
STQEASLVLGRPRNQEINN*KHFNGLFIKVQTNS
AILM*TRSCNIQ**K*NEKEVPPSDSGHPGIKR
ERTFLVTQSQCLVWGQSTMDPKGQNMLQANQHS
CCRRN*DQPLWAMKDNGGRAT*RAVGPRLVQPTW
HRIFPCTSFPPVTCSIRGCCINSIFSSSHKMNG
VSLHICPEEAVMIPLLLHLIIFN*EQLMITIHK
IHILRQ*FFMSQTQSILHEEAEKGEEKNKPNG*C
*L*DRVCL*YSLICSL*EHIFTVMFLHRKTIFS
GQQLFL*WDGGVYTRIESVRVEQLGSRWWGHF*
SGNN*KKRRTLPWRGR**EIKRCL*LFCIIKWAL
EIGRRMMDSFWINQKGNTKEKSGR*REKKGGKE
KEWE*NKEVRDTIFAEQPVCFRMIQRKI*NRNK
CRLGISYKS*RWGVCGCVCVCVYTIVCL*NVYVH
E*GCVCVCIKIPE*PWHLGVQVIPPELFAGFRS
GVRISFL*KGI*RHRADAVFVILS*PNKVFA*V
TITKF*AVL*FDI*ESLLFILILYIHA*YTIEDA
SFNLSVI*SNMIRVFNNWVP*ISG*ENFQFWP*
ERKKNKQPSFFFLCFKTVVF*KSNN*LRPH*KS
FLFLYCYVISSIMLF*QVAISQNLYVDVNAHFLC
FFY*TSVDFGGGHLFTNEK*AQSKKWNHLLTRI
L*NCQGSSNLKPHPTDGSPNSTWAIGTIFIWLS
LLNILNEFSTKCASHWGRKTSKIPVARNSFYSEG
GWHGD*NSQENEIRVRLEVLM*NGRTQEGGSSL
PEDF*PEVPDAWAENPAIRGRSQSRHRDKNRGG
SSIAQPQAQWQLGWLESRIVLWVAQKM*CASCFL
*LMDLVETIDMI*TNFPIFHKRKPSL*LTLKFF
VLF*RKPCAS*NLQLTRECTAKRKA*EATLFAE
WL*RQMKWSLTTVD*TRALIA*RITEF*SWGFLG
HAPCVDKERNTVSGTLPQSQSCFHCGPYIS*LL
LLLLCCLPDYCCLSSCSTH*RSYYNPMKM*ITV
YLGEPDFLCALEFFIHSRNLGPPLCT*HRARLWD
PKWTLLTF*RWDRPLEESHSCLIHREKEAYEKL
CL*CSAPPPNSTQAC*PHLLQNV*IL*VLKAFL
EVLHSAVFIGVHFPPELINY*HDLAFSSRNYGNR
VCQWQEAVLCFTWMTQCSLLASSYPCMLLTLDN
DI*AVYRSMSTYIYTHTYIYIKCNKEH*NSVDS
CL*RQIIKPFFSQLKNGFN*TMY*KKSSLSVRDG
EYIPF*LKNKFPEF*AFSELPILILCCSLPKLF
FLCFSFFGGGGEKSSNTVFGNYTLYLVFLCMLT
T*MLLSCFGFRVIVRHSMQVYSYFLIKIQCVLSF
YK

Frame 2

RASPPCAQLCPPPLERIPSRPWAFSRVLAKPPG
VPISFLG*LQRVFFLSSFPCLCALLQDGRGGIA
QGKAASHSRKKKEAD*NRRQATTA*RADTSAAA
FQVQSASGEMAAAGHTRWNCRRGGSQEAAV*RG*
VQSQAT*R*HSEAGARNTNARK*RVPDICQRAN
HPRETEGNRKILQGLSEGFLQYGWRCSKLHFLP
ASRPANPLFTNSRTITWAGRDQQSGWSRVGECAA
KGR*VSLERHRNIRPRHDYQEASPAF*G*YLAK
KRGRQL*CHPPGACCQLSFPRSQKHGN*GVCCR
M*KCSWNHLYPTSHGPSLRFLFTPA*WPPY*SPR
IPG**CCQRDPLSR*GARGQLL*FCCGWNVQWN
ILPRAWCSGSGGRPKPPCPRGDPARTH*KNS*P
AGTSSHRAQ**QP*PHGRGRKNKWPFPQPA*RCA
GGQPAGACQPQLHNQLTVFFPRWRVHSHHTEKG
GQV*AACLP*GQEALQAL*G*RA*ERTILH*KS
EAFRGDAGAGKGEERAHPQPGRQEESWHCSKMVE
SPAGKNHRGAAGRGTSGVAQKVQGAQREKGTAG
TVAAAEAVTAAAAAAPIAALHSPCLFS*TRKHD
*QSKGGHCHRADRFLCCSQTISADGEFQASGGQG
PEYTQAVLHQAFLQASGVSQLRQATD*SETTFC
RGTSRRQWCLSRQGTEIPRCPGDPIGSRKPGQH
SLSGEGRALQRAF*TWALI*TVG*GWRIYERPGC
PHCGQG**PWDFGSVLKICQCLLDPRGA*LWSG
RIVGEVSGYHSPGDPIQ*FQHGQHQ*QRGIQ*D
NQCPPGKFTG*FFSAPDTTN*QPLRGPRRRRLQV
I**SWFLFPFLHAGGLSVG**PLGVSGWPPGAE
CHSTSHSRAGG*SCVQNQQGWSRATGT*SDCRG
S*SCGFRLRKASEHV*ATSGVFSCSREKGCITKD
SAC*RQGAQGKGAPPATASCAAQWPD*HGGDQA
RRKLFQQVLGGS*AEKHSLPPGHSRI*RDGWAF
QAEVQETADFVHD*GRDPSSSGKGRGAEEAETSL
AEYAEPQDKECPITALQNMLQNCSRENRESQTS
SI
PHH*RPQLAA*LSP*RGCRNPAAQESDADPH
GRL*DTQI*KARENG***LHF*VTVLQGDFRGPR
GHTG*SKKERTGFALGSRDLCQPGGRRQRINFL
QPRKRLWCLGDQETKKLTTESILMDYLLKCKQT
QQSLCRPEAAIYNDENETKRKSPHQTLDTQESKE
KGLFW*LNPSVWFGANLQWIQKDKTCYKQINIV
AAGGTETSLSGR*RTMVVGPLREQ*GPGWCSLH
GTGYFPAPVSHLSLAASEGVALTPFSPAAIK*MA
FLSIFAQKRQL*FHFSYI*LFLIENNS*SQFIK
SIF*DNSSSCHKHNLFYMRRLRKGKRKTNQMDD
VSFRIVSAYNIH*SAVYENTFSQLCFFIGKLYLV
GNNYFYDGMGEYIHV*NLYALNNLVQDGGGIFR
AAIIEKKGELCLGEVDDKK*KGVYNYFVL*SGP
*R*EEE*WIPFGSIRKETRKKSQEGRERKREGRR
KNGNKIRR*EILFLLSNQCVSG*YKEKYRIEIS
AGLESATNPKDGVCVDVCVCVCTPLCVCKMCMF
MSKGVCVCVLKFQSDRGTWVYR*FLQSCLLASGV
E*EFLFYEKGYKGTELMQYL*Y*VDLTRYLHES
QLQSFERFCNLTFRRVSYLFSYFTFMLSIL*RM
PALIFLSFKAI**GYSIIGCPKFLDEKIFNSGHE
KEKKINSLLFFSFVLKLWFFKKAIINSDLTKNH
FCFYIVMS*ALLCYSNK*QFHKICM*MLTHISF
ASFIRLVLTLGGDIYSQMRSRHKVKNGTIY*QGS
FKTAKGALT*SHILQMAAQIAHGQLAPSLYG*V
S*IF*MNSQQNVLATGDAKQVRSLLQEIHFIVR
EVGMETKILRKMRSVLD*KS*CEMGGLRKEDRLY
LRISSQRSQMPGLRTQR*GGVPKADTGIRTEEA
AALHSPRHSGS*DGWRVG*FYGLPKKCDALHVF
SDSWIW*RP*T*YRLTSPFFTRGNHPYDLP*SFL
FCFEGNHVLHETYS*QENVQLREKLKRPHYSRN
GFRGR*SGL*PQLIEPEHLLLKE*QSSRAGGSW
AMLRVWIRKEILFLGLSHSHKAVFTVAPTSLNFC
YYSYAAFRITAVYLLAPLTEDPIIIP*KCKLQF
TWESQIFSVLLSFLFIQETLGHRFVHSTVLGSG
IPNGPF*LSEDGTVPWRKVIPA*SIERKRLTKNF
ASDAQPHPQIAHKLVNPTSYKMFRFCRC*KPFW
KYCILPCL*VFTFLQS*LTTDMTWLSHPEIMET
GSVSGRRPCCVLLG*HNAVYLPLHTHACCSP*TM
TYKPYIDQCPHIYTHTHIYI*SVTRNTKTVLIL
VSEDK*LNLFFPN*RMDLIKLCIEKKVA*VLEM
VNIFHFS*RTNFLNFKHSVSCQF*FCVALYPNYF
FFVFLFLGEEGKKAAILCLEIILCIWFSCVC*P
LKCYYPALVLE*L*GIQCKYTVIFSLKSNVC*V
FI

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