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Sequences

Sequence NM_199229

ACTCGTGGGTAACTTGCTTTTGGGAGCCAGCGGTATGGCGTCGGGCTGCAAGATTGGCCCGTCCATCCTCAACAGCGACCTGGCCAATTTAGGGGCCGAG
TGCCTCCGGATGCTAGACTCTGGGGCCGATTATCTGCACCTGGACGTAATGGACGGGCATTTTGTTCCCAACATCACCTTTGGTCACCCTGTGGTAGAAA
GCCTTCGAAAGCAGCTAGGCCAGGACCCTTTCTTTGACATGCACATGATGGTGTCCAAGCCAGAACAGTGGGTAAAGCCAATGGCTGTAGCAGGAGCCAA
TCAGTACACCTTTCATCTCGAGGCTACTGAGAACCCAGGGGCTTTGATTAAAGACATTCGGGAGAATGGGATGAAGGTTGGCCTTGCCATCAAACCAGGA
ACCTCAGTTGAGTATTTGGCACCATGGGCTAATCAGATAGATATGGCCTTGGTTATGACAGTGGAACCGGGGTTTGGAGGGCAGAAATTCATGGAAGATA
TGATGCCAAAGGTTCACTGGTTGAGGACCCAGTTCCCATCTTTGGATATAGAGGTCGATGGTGGAGTAGGTCCTGACACTGTCCATAAATGTGCAGAGGC
AGGAGCTAACATGATTGTGTCTGGCAGTGCTATTATGAGGAGTGAAGACCCCAGATCTGTGATCAATCTATTAAGAAATGTTTGCTCAGAAGCTGCTCAG
AAACGTTCTCTTGATCGGTGAAACCATAAGGAGCCCAGTGTTCCTGTTCATGAAATCTCCCTTTTACTGGAAAACAGGAATATTGACTACCAAATCACAA
TGCAATTGAAGCCGTACTGCTTTTTTGAGCAGTTATTCATTCCAGTGATTAAAACTGATTGTGCAGAATATTCTAAGAGGTCAGAAATTGGTGTGTATAA
CTACATTTTTAGTGATGCAATTTATTGATTAGTGAGTAAGATACTGTTTTTATTGAGAGATTTGATTTTTATAAAGTAAAAATACGGCTGCATTAGGGTT
ACAAACAGAAAAGTGTCTTAATGTCTAAGGAGGGCATATTAGCTACACTACAAAAACAAATTTTGTCTGTACTTCTGAAAAGAATTTTGTTGTTTCTCAG
CTGTTTTCCAAAAGCAAAGGAAGTCTTTATGGTTTTTTTCTATTTCATGTTATTGTGATTTGTTTATAAGTTTGGGTGGGGTGCATACCATATTCTTGGT
TCTTAAAATCTATCACTTTTCACCTTACACTTGATGTGTGAAAACTATAAAAACAATGTGTGAAACCCAGGGGTTCTAAAATACAAGCATAGATTTTATC
AGGGTGTTTTGTCAAAGCAGGTTATTCAGTGATTCCTCCCCACCATTCTTAAGAACGTTAAATAATGCTGTTGTGTTAGCTCTGAGTAGAAAGGAAAAAG
TAAAACCTCTGTTTGGAGGTAATATTGGGTTGAATTCTGACTGCCCCTTTCTAGCTGGACCTTTAACAAATCACCCAATCTTTTTTGTGTTTCTCTAAAG
TCATTTATACATTAAATGTAATTATAGCAACTGTGGGGTTCTGTTGAGAATTAAGAGCTAACACTATATATGTAAAGTTTCCAGTACTAGTCCCAGAATT
TAGAATATGCTCAACACAAAGTAAACAGCATTATATAAGTTTATATTTTTGTGAGTTATAAAGTACTTTGATATATTCTCATTAAATCTGTAAATCACCT
CTATAAGTAAGTGGTAATAATAAAGCAGATATTTTTGTCCCCATTTAAAAAATGAAGAAATTAATGCTTAATAGGGTGGTACCCTGGAAAGGATCTGGGA
AGTGGTAGAATTTCTGGTCTGTACTTTTACAAATGGAGCCCTTGGGAGGTGGGTTAGGTAAAAGAAGCTTTTTACTTAACGTTGTCTTATTTCCAGTCTA
ATTTTACGCTGTAGCAGAACCAGATGGCTGAGAAAATTCTGGAACTATGGATCTTGACCCCAAGGATATATTATTTTATTCCAAGAAAGATCAGGTAGGC
GAAAAGATGACAGGATACAGAGTCAATCCATAAACTAAATATTTATAACTGTTCTGAATTATACAGAGTCTAAAAATATGTGTCAGCTACTTCATTCCTG
TAAATACTCTTGCTGTGTTATAAATATGGCAAGAAATAAACATGACCAATATCAATAGACTTCTTGAGGCTACTATAAGTTTTGAGAAATAAGGTTCAAA
AAATAAGAATGCTAACACTTAAGCACAGACTAGAGCTTGCTTGGGTTTCTTCCTGCATTACAAGGTAAAAATTTGTTAATGTTTGTTTTTATTCAGCTTG
GGAAAGCTTTGTGCCATGAATACGTCGCATTTAATAACAAGCAACACACGGCATATAGAAATAACTTTAATTAAAAAACTTACATAGAAGATTATAATAT
CAGACGTGACAAAGATTTGAGTTTATTTGCCTGGACAACTTGGGTTTGTCTGGCTTTTGTTTTCTTTTTCTTTAAAAATAAATGTACAGTAAAACTA
  • refseq_RPE.F3 (forward primer)
  • refseq_RPE.R3 (reverse primer)
  • Single exon skipping

Frame 0

TRG*LAFGSQRYGVGLQDWPVHPQQRPGQFRGR
VPPDARLWGRLSAPGRNGRAFCSQHHLWSPCGRK
PSKAARPGPFL*HAHDGVQARTVGKANGCSRSQ
SVHLSSRGY*EPRGFD*RHSGEWDEGWPCHQTR
NLS*VFGTMG*SDRYGLGYDSGTGVWRAEIHGRY
DAKGSLVEDPVPIFGYRGRWWSRS*HCP*MCRG
RS*HDCVWQCYYEE*RPQICDQSIKKCLLRSCS
ETFS*SVKP*GAQCSCS*NLPFTGKQEY*LPNHN
AIEAVLLF*AVIHSSD*N*LCRIF*EVRNWCV*
LHF**CNLLISE*DTVFIERFDFYKVKIRLH*G
YKQKSVLMSKEGILATLQKQILSVLLKRILLFLS
CFPKAKEVFMVFFYFMLL*FVYKFGWGAYHILG
S*NLSLFTLHLMCENYKNNV*NPGVLKYKHRFY
QGVLSKQVIQ*FLPTILKNVK*CCCVSSE*KGKS
KTSVWR*YWVEF*LPLSSWTFNKSPNLFCVSLK
SFIH*M*L*QLWGSVEN*ELTLYM*SFQY*SQN
LEYAQHKVNSII*VYIFVSYKVL*YILIKSVNHL
YK*VVIIKQIFLSPFKK*RN*CLIGWYPGKDLG
SGRISGLYFYKWSPWEVG*VKEAFYLTLSYFQS
NFTL*QNQMAEKILELWILTPRIYYFIPRKIR*A
KR*QDTESIHKLNIYNCSELYRV*KYVSATSFL
*ILLLCYKYGKK*T*PISIDFLRLL*VLRNKVQ
KIRMLTLKHRLELAWVSSCITR*KFVNVCFYSAW
ESFVP*IRRI**QATHGI*K*L*LKNLHRRL*Y
QT*QRFEFICLDNLGLSGFCFLFL*K*MYSKT

Frame 1

LVGNLLLGASGMASGCKIGPSILNSDLANLGAE
CLRMLDSGADYLHLDVMDGHFVPNITFGHPVVE
SLRKQLGQDPFFDMHMMVSKPEQWVKPMAVAGAN
QYTFHLEATENPGALIKDIRENGMKVGLAIKPG
TSVEYLAPWANQIDMALVMTVEPGFGGQKFMED
MMPKVHWLRTQFPSLDIEVDGGVGPDTVHKCAEA
GANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQ
KRSLDR*NHKEPSVPVHEISLLLENRNIDYQIT
MQLKPYCFFEQLFIPVIKTDCAEYSKRSEIGVYN
YIFSDAIY*LVSKILFLLRDLIFIK*KYGCIRV
TNRKVS*CLRRAY*LHYKNKFCLYF*KEFCCFS
AVFQKQRKSLWFFSISCYCDLFISLGGVHTIFLV
LKIYHFSPYT*CVKTIKTMCETQGF*NTSIDFI
RVFCQSRLFSDSSPPFLRTLNNAVVLALSRKEK
VKPLFGGNIGLNSDCPFLAGPLTNHPIFFVFL*S
HLYIKCNYSNCGVLLRIKS*HYICKVSSTSPRI
*NMLNTK*TALYKFIFL*VIKYFDIFSLNL*IT
SISKW***SRYFCPHLKNEEINA**GGTLERIWE
VVEFLVCTFTNGALGRWVR*KKLFT*RCLISSL
ILRCSRTRWLRKFWNYGS*PQGYIILFQERSGR
RKDDRIQSQSIN*IFITVLNYTESKNMCQLLHSC
KYSCCVINMARNKHDQYQ*TS*GYYKF*EIRFK
K*EC*HLSTD*SLLGFLPALQGKNLLMFVFIQL
GKALCHEYVAFNNKQHTAYRNNFN*KTYIEDYNI
RRDKDLSLFAWTTWVCLAFVFFFFKNKCTVKL

Frame 2

SWVTCFWEPAVWRRAARLARPSSTATWPI*GPS
ASGC*TLGPIICTWT*WTGILFPTSPLVTLW*K
AFESS*ARTLSLTCT*WCPSQNSG*SQWL*QEP
ISTPFISRLLRTQGL*LKTFGRMG*RLALPSNQE
PQLSIWHHGLIR*IWPWL*QWNRGLEGRNSWKI
*CQRFTG*GPSSHLWI*RSMVE*VLTLSINVQR
QELT*LCLAVLL*GVKTPDL*SIY*EMFAQKLLR
NVLLIGETIRSPVFLFMKSPFYWKTGILTTKSQ
CN*SRTAFLSSYSFQ*LKLIVQNILRGQKLVCI
TTFLVMQFID**VRYCFY*EI*FL*SKNTAALGL
QTEKCLNV*GGHISYTTKTNFVCTSEKNFVVSQ
LFSKSKGSLYGFFLFHVIVICL*VWVGCIPYSW
FLKSITFHLTLDV*KL*KQCVKPRGSKIQA*ILS
GCFVKAGYSVIPPHHS*ER*IMLLC*L*VERKK
*NLCLEVILG*ILTAPF*LDL*QITQSFLCFSK
VIYTLNVIIATVGFC*ELRANTIYVKFPVLVPEF
RICSTQSKQHYISLYFCEL*STLIYSH*ICKSP
L*VSGNNKADIFVPI*KMKKLMLNRVVPWKGSG
KW*NFWSVLLQMEPLGGGLGKRSFLLNVVLFPV*
FYAVAEPDG*ENSGTMDLDPKDILFYSKKDQVG
EKMTGYRVNP*TKYL*LF*IIQSLKICVSYFIP
VNTLAVL*IWQEINMTNINRLLEATISFEK*GSK
NKNANT*AQTRACLGFFLHYKVKIC*CLFLFSL
GKLCAMNTSHLITSNTRHIEITLIKKLT*KIII
SDVTKI*VYLPGQLGFVWLLFSFSLKINVQ*N

Sequence NM_006916

ACTCGTGGGTAACTTGCTTTTGGGAGCCAGCGGTATGGCGTCGGGCTGCAAGATTGGCCCGTCCATCCTCAACAGCGACCTGGCCAATTTAGGGGCCGAG
TGCCTCCGGATGCTAGACTCTGGGGCCGATTATCTGCACCTGGACGTAATGGACGGACATGCACATGATGGTGTCCAAGCCAGAACAGTGGGTAAAGCCA
ATGGCTGTAGCAGGAGCCAATCAGTACACCTTTCATCTCGAGGCTACTGAGAACCCAGGGGCTTTGATTAAAGACATTCGGGAGAATGGGATGAAGTCTT
GCTCTGTCACCCAGGCTGAAGTGCAGTGGCACAGTCAGGGCCCATTGCAGGTTGGCCTTGCCATCAAACCAGGAACCTCAGTTGAGTATTTGGCACCATG
GGCTAATCAGATAGATATGGCCTTGGTTATGACAGTGGAACCGGGGTTTGGAGGGCAGAAATTCATGGAAGATATGATGCCAAAGGTTCACTGGTTGAGG
ACCCAGTTCCCATCTTTGGATATAGAGGTCGATGGTGGAGTAGGTCCTGACACTGTCCATAAATGTGCAGAGGCAGGAGCTAACATGATTGTGTCTGGCA
GTGCTATTATGAGGAGTGAAGACCCCAGATCTGTGATCAATCTATTAAGAAATGTTTGCTCAGAAGCTGCTCAGAAACGTTCTCTTGATCGGTGAAACCA
TAAGGAGCCCAGTGTTCCTGTTCATGAAATCTCCCTTTTACTGGAAAACAGGAATATTGACTACCAAATCACAATGCAATTGAAGCCGTACTGCTTTTTT
GAGCAGTTATTCATTCCAGTGATTAAAACTGATTGTGCAGAATATTCTAAGAGGTCAGAAATTGGTGTGTATAACTACATTTTTAGTGATGCAATTTATT
GATTAGTGAGTAAGATACTGTTTTTATTGAGAGATTTGATTTTTATAAAGTAAAAATACGGCTGCATTAGGGTTACAAACAGAAAAGTGTCTTAATGTCT
AAGGAGGGCATATTAGCTACACTACAAAAACAAATTTTGTCTGTACTTCTGAAAAGAATTTTGTTGTTTCTCAGCTGTTTTCCAAAAGCAAAGGAAGTCT
TTATGGTTTTTTTCTATTTCATGTTATTGTGATTTGTTTATAAGTTTGGGTGGGGTGCATACCATATTCTTGGTTCTTAAAATCTATCACTTTTCACCTT
ACACTTGATGTGTGAAAACTATAAAAACAATGTGTGAAACCCAGGGGTTCTAAAATACAAGCATAGATTTTATCAGGGTGTTTTGTCAAAGCAGGTTATT
CAGTGATTCCTCCCCACCATTCTTAAGAACGTTAAATAATGCTGTTGTGTTAGCTCTGAGTAGAAAGGAAAAAGTAAAACCTCTGTTTGGAGGTAATATT
GGGTTGAATTCTGACTGCCCCTTTCTAGCTGGACCTTTAACAAATCACCCAATCTTTTTTGTGTTTCTCTAAAGTCATTTATACATTAAATGTAATTATA
GCAACTGTGGGGTTCTGTTGAGAATTAAGAGCTAACACTATATATGTAAAGTTTCCAGTACTAGTCCCAGAATTTAGAATATGCTCAACACAAAGTAAAC
AGCATTATATAAGTTTATATTTTTGTGAGTTATAAAGTACTTTGATATATTCTCATTAAATCTGTAAATCACCTCTATAAGTAAGTGGTAATAATAAAGC
AGATATTTTTGTCCCCATTTAAAAAATGAAGAAATTAATGCTTAATAGGGTGGTACCCTGGAAAGGATCTGGGAAGTGGTAGAATTTCTGGTCTGTACTT
TTACAAATGGAGCCCTTGGGAGGTGGGTTAGGTAAAAGAAGCTTTTTACTTAACGTTGTCTTATTTCCAGTCTAATTTTACGCTGTAGCAGAACCAGATG
GCTGAGAAAATTCTGGAACTATGGATCTTGACCCCAAGGATATATTATTTTATTCCAAGAAAGATCAGGTAGGCGAAAAGATGACAGGATACAGAGTCAA
TCCATAAACTAAATATTTATAACTGTTCTGAATTATACAGAGTCTAAAAATATGTGTCAGCTACTTCATTCCTGTAAATACTCTTGCTGTGTTATAAATA
TGGCAAGAAATAAACATGACCAATATCAATAGACTTCTTGAGGCTACTATAAGTTTTGAGAAATAAGGTTCAAAAAATAAGAATGCTAACACTTAAGCAC
AGACTAGAGCTTGCTTGGGTTTCTTCCTGCATTACAAGGTAAAAATTTGTTAATGTTTGTTTTTATTCAGCTTGGGAAAGCTTTGTGCCATGAATACGTC
GCATTTAATAACAAGCAACACACGGCATATAGAAATAACTTTAATTAAAAAACTTACATAGAAGATTATAATATCAGACGTGACAAAGATTTGAGTTTAT
TTGCCTGGACAACTTGGGTTTGTCTGGCTTTTGTTTTCTTTTTCTTTAAAAATAAATGTACAGTAAAACTA
  • refseq_RPE.F3 (forward primer)
  • refseq_RPE.R3 (reverse primer)
  • Single exon skipping

Frame 0

TRG*LAFGSQRYGVGLQDWPVHPQQRPGQFRGR
VPPDARLWGRLSAPGRNGRTCT*WCPSQNSG*SQ
WL*QEPISTPFISRLLRTQGL*LKTFGRMG*SL
ALSPRLKCSGTVRAHCRLALPSNQEPQLSIWHH
GLIR*IWPWL*QWNRGLEGRNSWKI*CQRFTG*G
PSSHLWI*RSMVE*VLTLSINVQRQELT*LCLA
VLL*GVKTPDL*SIY*EMFAQKLLRNVLLIGET
IRSPVFLFMKSPFYWKTGILTTKSQCN*SRTAFL
SSYSFQ*LKLIVQNILRGQKLVCITTFLVMQFI
D**VRYCFY*EI*FL*SKNTAALGLQTEKCLNV
*GGHISYTTKTNFVCTSEKNFVVSQLFSKSKGSL
YGFFLFHVIVICL*VWVGCIPYSWFLKSITFHL
TLDV*KL*KQCVKPRGSKIQA*ILSGCFVKAGY
SVIPPHHS*ER*IMLLC*L*VERKK*NLCLEVIL
G*ILTAPF*LDL*QITQSFLCFSKVIYTLNVII
ATVGFC*ELRANTIYVKFPVLVPEFRICSTQSK
QHYISLYFCEL*STLIYSH*ICKSPL*VSGNNKA
DIFVPI*KMKKLMLNRVVPWKGSGKW*NFWSVL
LQMEPLGGGLGKRSFLLNVVLFPV*FYAVAEPD
G*ENSGTMDLDPKDILFYSKKDQVGEKMTGYRVN
P*TKYL*LF*IIQSLKICVSYFIPVNTLAVL*I
WQEINMTNINRLLEATISFEK*GSKNKNANT*A
QTRACLGFFLHYKVKIC*CLFLFSLGKLCAMNTS
HLITSNTRHIEITLIKKLT*KIIISDVTKI*VY
LPGQLGFVWLLFSFSLKINVQ*N

Frame 1

LVGNLLLGASGMASGCKIGPSILNSDLANLGAE
CLRMLDSGADYLHLDVMDGHAHDGVQARTVGKA
NGCSRSQSVHLSSRGY*EPRGFD*RHSGEWDEVL
LCHPG*SAVAQSGPIAGWPCHQTRNLS*VFGTM
G*SDRYGLGYDSGTGVWRAEIHGRYDAKGSLVE
DPVPIFGYRGRWWSRS*HCP*MCRGRS*HDCVWQ
CYYEE*RPQICDQSIKKCLLRSCSETFS*SVKP
*GAQCSCS*NLPFTGKQEY*LPNHNAIEAVLLF
*AVIHSSD*N*LCRIF*EVRNWCV*LHF**CNLL
ISE*DTVFIERFDFYKVKIRLH*GYKQKSVLMS
KEGILATLQKQILSVLLKRILLFLSCFPKAKEV
FMVFFYFMLL*FVYKFGWGAYHILGS*NLSLFTL
HLMCENYKNNV*NPGVLKYKHRFYQGVLSKQVI
Q*FLPTILKNVK*CCCVSSE*KGKSKTSVWR*Y
WVEF*LPLSSWTFNKSPNLFCVSLKSFIH*M*L*
QLWGSVEN*ELTLYM*SFQY*SQNLEYAQHKVN
SII*VYIFVSYKVL*YILIKSVNHLYK*VVIIK
QIFLSPFKK*RN*CLIGWYPGKDLGSGRISGLYF
YKWSPWEVG*VKEAFYLTLSYFQSNFTL*QNQM
AEKILELWILTPRIYYFIPRKIR*AKR*QDTES
IHKLNIYNCSELYRV*KYVSATSFL*ILLLCYKY
GKK*T*PISIDFLRLL*VLRNKVQKIRMLTLKH
RLELAWVSSCITR*KFVNVCFYSAWESFVP*IR
RI**QATHGI*K*L*LKNLHRRL*YQT*QRFEFI
CLDNLGLSGFCFLFL*K*MYSKT

Frame 2

SWVTCFWEPAVWRRAARLARPSSTATWPI*GPS
ASGC*TLGPIICTWT*WTDMHMMVSKPEQWVKP
MAVAGANQYTFHLEATENPGALIKDIRENGMKS
CSVTQAEVQWHSQGPLQVGLAIKPGTSVEYLAPW
ANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLR
TQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSG
SAIMRSEDPRSVINLLRNVCSEAAQKRSLDR*NH
KEPSVPVHEISLLLENRNIDYQITMQLKPYCFF
EQLFIPVIKTDCAEYSKRSEIGVYNYIFSDAIY
*LVSKILFLLRDLIFIK*KYGCIRVTNRKVS*CL
RRAY*LHYKNKFCLYF*KEFCCFSAVFQKQRKS
LWFFSISCYCDLFISLGGVHTIFLVLKIYHFSP
YT*CVKTIKTMCETQGF*NTSIDFIRVFCQSRLF
SDSSPPFLRTLNNAVVLALSRKEKVKPLFGGNI
GLNSDCPFLAGPLTNHPIFFVFL*SHLYIKCNY
SNCGVLLRIKS*HYICKVSSTSPRI*NMLNTK*T
ALYKFIFL*VIKYFDIFSLNL*ITSISKW***S
RYFCPHLKNEEINA**GGTLERIWEVVEFLVCT
FTNGALGRWVR*KKLFT*RCLISSLILRCSRTRW
LRKFWNYGS*PQGYIILFQERSGRRKDDRIQSQ
SIN*IFITVLNYTESKNMCQLLHSCKYSCCVIN
MARNKHDQYQ*TS*GYYKF*EIRFKK*EC*HLST
D*SLLGFLPALQGKNLLMFVFIQLGKALCHEYV
AFNNKQHTAYRNNFN*KTYIEDYNIRRDKDLSL
FAWTTWVCLAFVFFFFKNKCTVKL

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