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Sequences

Sequence NM_130843

GCCTCCCGCCGCCTCCCGCGCGGCCATGGACTGAGCGCCGCCGGCCAGGCCGCGGGGATGGGGCCGCCGCTCCCGCTGCTGCTGCTGCTACTGCTGCTGC TGCCGCCACGCGTCCTGCCTGCCGCCCCTTCGTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTGCTCGAGGAGGGCCTCTGCGGAGC GTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGGTGCCAGAAGGTTCCGGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAGCGC CTGCGCGTGGCGTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTATACTCAGTATGTGATGGACCAGGAACTTGCAGACCTCCCGAAAA CCTACCTGAGGCGTCCTGAAGCATCCAGCCCAGCCAGGCCCTCAAAACACAGCGTTGGCAGCGAGAGGAGGTACAGTCGGGAGGGCGGTGCTGCCCTGGC CAACGCCCTCCGACGCCACCTGCCCTTCCTGGAGGCCCTGTCCCAGGCCCCAGCCTCAGACGTGCTCGCCAGGACCCATACGGCGCAGGACAGACCCCCC GCTGAGGGTGATGACCGCTTCTCCGAGAGCATCCTGACCTATGTGGCCCACACGTCTGCGCTGACCTACCCTCCCGGGTCCCGGACCCAGCTCCGCGAGG ACCTCCTGCCGCGGACCCTCGGCCAGCTCCAGCCAGATGAGCTCAGCCCTAAGGTGGACAGTGGTGTGGACAGACACCATCTGATGGCGGCCCTCAGTGC CTATGCTGCCCAGAGGCCCCCAGCTCCCCCCGGGGAGGGCAGCCTGGAGCCACAGTACCTTCTGCGTGCACCCTCAAGAATGCCCAGGCCTTTGCTGGCA CCAGCCGCCCCCCAGAAGTGGCCTTCACCTCTGGGAGATTCCGAAGACCCCTCCAGCACAGGCGATGGAGCACGGATTCATACCCTCCTGAAGGACCTGC AGAGGCAGCCGGCTGAGGTGAGGGGCCTGAGTGGCCTGGAGCTGGACGGCATGGCTGAGCTGATGGCTGGCCTGATGCAAGGCGTGGACCATGGAGTAGC TCGAGGCAGCCCTGGGAGAGCGGCCCTGGGAGAGTCTGGAGAACAGGCGGATGGCCCCAAGGCCACCCTCCGTGGAGACAGCTTTCCAGATGACGGAGTG CAGGACGACGATGATAGACTTTACCAAGAGGTCCATCGTCTGAGTGCCACACTCGGGGGCCTCCTGCAGGACCACGGGTCTCGACTCTTACCTGGAGCCC TCCCCTTTGCAAGGCCCCTCGACATGGAGAGGAAGAAGTCCGAGCACCCTGAGTCTTCCCTGTCTTCAGAAGAGGAGACTGCCGGAGTGGAGAACGTCAA GAGCCAGACGTATTCCAAAGATCTGCTGGGGCAGCAGCCGCATTCGGAGCCCGGGGCCGCTGCGTTTGGGGAGCTCCAAAACCAGATGCCTGGGCCCTCG AAGGAGGAGCAGAGCCTTCCAGCGGGTGCTCAGGAGGCCCTCAGCGACGGCCTGCAATTGGAGGTCCAGCCTTCCGAGGAAGAGGCGCGGGGCTACATCG TGACAGACAGAGAGGTTCTCGGACCAGCAGTGACCTTCAAAGTGAGCGCCAATGTCCAAAACGTGACCACTGAGGATGTGGAGAAGGCCACAGTTGACAA CAAAGACAAACTGGAGGAAACCTCTGGACTGAAAATTCTTCAAACCGGAGTCGGGTCGAAAAGCAAACTCAAGTTCCTGCCTCCTCAGGCGGAGCAAGAA GACTCCACCAAGTTCATCGCGCTCACCCTGGTCTCCCTCGCCTGCATCCTGGGCGTCCTCCTGGCCTCTGGCCTCATCTACTGCCTCCGCCATAGCTCTC AGCACAGGCTGAAGGAGAAGCTCTCGGGACTAGGGGGCGACCCAGGTGCAGATGCCACTGCCGCCTACCAGGAGCTGTGCCGCCAGCGTATGGCCACGCG GCCACCAGACCGACCTGAGGGCCCGCACACGTCACGCATCAGCAGCGTCTCATCCCAGTTCAGCGACGGGCCGATCCCCAGCCCCTCCGCACGCAGCAGC GCCTCATCCTGGTCCGAGGAGCCTGTGCAGTCCAACATGGACATCTCCACCGGCCACATGATCCTGTCCTACATGGAGGACCACCTGAAGAACAAGAACC GGCTGGAGAAGGAGTGGGAAGCGCTGTGCGCCTACCAGGCGGAGCCCAACAGCTCGTTCGTGGCCCAGAGGGAGGAGAACGTGCCCAAGAACCGCTCCCT GGCCGTGCTGACCTATGACCACTCCCGGGTCCTGCTGAAGGCGGAGAACAGCCACAGCCACTCAGACTACATCAACGCTAGCCCCATCATGGATCACGAC CCGAGGAACCCCGCGTACATCGCCACCCAGGGACCGCTGCCCGCCACCGTGGCTGACTTTTGGCAGATGGTGTGGGAGAGCGGCTGCGTGGTGATCGTCA TGCTGACACCCCTCGCGGAGAACGGCGTCCGGCAGTGCTACCACTACTGGCCGGATGAAGGCTCCAATCTCTACCACATCTATGAGGTGAACCTGGTCTC CGAGCACATCTGGTGTGAGGACTTCCTGGTGAGGAGCTTCTATCTGAAGAACCTGCAGACCAACGAGACGCGCACCGTGACGCAGTTCCACTTCCTGAGT TGGTATGACCGAGGAGTCCCTTCCTCCTCAAGGTCCCTCCTGGACTTCCGCAGAAAAGTAAACAAGTGCTACAGGGGCCGTTCTTGTCCAATAATTGTTC ATTGCAGTGACGGTGCAGGCCGGAGCGGCACCTACGTCCTGATCGACATGGTTCTCAACAAGATGGCCAAAGGTGCTAAAGAGATTGATATCGCAGCGAC CCTGGAGCACTTGAGGGACCAGAGACCCGGCATGGTCCAGACGAAGGAGCAGTTTGAGTTCGCGCTGACAGCCGTGGCTGAGGAGGTGAACGCCATCCTC AAGGCCCTTCCCCAGTGAGCGGCAGCCTCAGGGGCCTCAGGGGAGCCCCCACCCCACGGATGTTGTCAGGAATCATGATCTGACTTTAATTGTGTGTCTT CTATTATAACTGCATAGTAATAGGGCCCTTAGCTCTCCCGTAGTCAGCGCAGTTTAGCAGTTAAAAGTGTATTTTTGTTTAATCAAACAATAATAAAGAG AGATTTGTGGAAAAATCCAGTTACGGGTGGAGGGGAATCGGTTCATCAATTTTCACTTGCTTAAAAAAAATACTTTTTCTTAAAGCACCCGTTCACCTTC TTGGTTGAAGTTGTGTTAACAATGCAGTAGCCAGCACGTTCGAGGCGGTTTCCAGGAAGAGTGTGCTTGTCATCTGCCACTTTCGGGAGGGTGGATCCAC TGTGCAGGAGTGGCCGGGGAAGCTGGCAGCACTCAGTGAGGCCGCCCGGCACACAAGGCACGTTTGGCATTTCTCTTTGAGAGAGTTTATCATTGGGAGA AGCCGCAGGGACAGAACTGAACGTCCTGCAGCTTCGGGGCAAGTGAGACAATCACAGCTCCTCGCTGCGTCTCCATCAACACTGCGCCGGGTACCATGGA CGGCCCCGTCAGCCACACCTGTCAGCCCAAGCAGAGTGATTCAGGGGCTCCCCGGGGGCAGACACCTGTGCACCCCATGAGTAGTGCCCACTTGAGGCTG GCACTCCCCTGACCTCACCTTTGCAAAGTTACAGATGCACCCCAACATTGAGATGTGTTTTTAATGTTAAAATATTGATTTCTACGTTATGAAAACAGAT GCCCCCGTGAATGCTTACCTGTGAGATAACCACAACCAGGAAGAACAAATCTGGGCATTGAGCAAGCTATGAGGGTCCCCGGGAGCACACGAACCCTGCC AGGCCCCCGCTGGCTCCTCCAGGCACGTCCCGGACCTGTGGGGCCCCAGAGAGGGGACATTTCCCTCCTGGGAGAGAAGGAGATCAGGGCAACTCGGAGA GGGCTGCGAGCATTTCCCTCCCGGGAGAGGAGATCAGGGCGACCTGCACGCACTGCGTAGAGCCTGGAAGGGAAGTGAGAAACCAGCCGACCGGCCCTGC CCCTCTTCCCGGGATCACTTAATGAACCACGTGTTTTGACATCATGTAAACCTAAGCACGTAGAGATGATTCGGATTTGACAAAATAACATTTGAGTATC CGATTCGCCATCACCCCCTACCCCAGAAATAGGACAATTCACTTCATTGACCAAGATGATCACATGGAAGGCGGCACAGAGGCAGCTGTGTGGGCTGCAG ATTTCCTGTGTGGGGTTCAGCGTAGAAAACGCACCTCCATCCCGCCCTTCCCACAGCATTCCTCCATCTTAGATAGATGGTACTCTCCAAAGGCCCTACC AGAGGGAACACGGCCTACTGAGCGGACAGAATGATGCCAAAATATTGCTTATGTCTCTACATGGTATTGTAATGAATATCTGCTTTAATATAGCTATCAT TTCTTTTCCAAAATTACTTCTCTCTATCTGGAATTTAATTAATCGAAATGAATTTATCTGAATATAGGAAGCATATGCCTACTTGTAATTTCTAACTCCT TATGTTTGAAGAGAAACCTCCGGTGTGAGATATACAAATATATTTAATTGTGTCATATTAAACTTCTGATT

refseq_PTPRN2.F4 (forward primer)
refseq_PTPRN2.R4 (reverse primer)
Single exon skipping

Frame 0

ASRRLPRGHGLSAAGQAAGMGPPLPLLLLLLLL LPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGA SEACVNDGVFGRCQKVPAMDFYRYEVSPVALQR LRVALQKLSGTGFTWQDDYTQYVMDQELADLPK TYLRRPEASSPARPSKHSVGSERRYSREGGAALA NALRRHLPFLEALSQAPASDVLARTHTAQDRPP AEGDDRFSESILTYVAHTSALTYPPGSRTQLRE DLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSA YAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLA PAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDL QRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVA RGSPGRAALGESGEQADGPKATLRGDSFPDDGV QDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGA LPFARPLDMERKKSEHPESSLSSEEETAGVENVK SQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPS KEEQSLPAGAQEALSDGLQLEVQPSEEEARGYI VTDREVLGPAVTFKVSANVQNVTTEDVEKATVDN KDKLEETSGLKILQTGVGSKSKLKFLPPQAEQE DSTKFIALTLVSLACILGVLLASGLIYCLRHSS QHRLKEKLSGLGGDPGADATAAYQELCRQRMATR PPDRPEGPHTSRISSVSSQFSDGPIPSPSARSS ASSWSEEPVQSNMDISTGHMILSYMEDHLKNKN RLEKEWEALCAYQAEPNSSFVAQREENVPKNRSL AVLTYDHSRVLLKAENSHSHSDYINASPIMDHD PRNPAYIATQGPLPATVADFWQMVWESGCVVIV MLTPLAENGVRQCYHYWPDEGSNLYHIYEVNLVS EHIWCEDFLVRSFYLKNLQTNETRTVTQFHFLS WYDRGVPSSSRSLLDFRRKVNKCYRGRSCPIIV HCSDGAGRSGTYVLIDMVLNKMAKGAKEIDIAAT LEHLRDQRPGMVQTKEQFEFALTAVAEEVNAIL KALPQ*AAASGASGEPPPHGCCQES*SDFNCVS SIITA***GP*LSRSQRSLAVKSVFLFNQTIIKR DLWKNPVTGGGESVHQFSLA*KKYFFLKHPFTF LVEVVLTMQ*PARSRRFPGRVCLSSATFGRVDP LCRSGRGSWQHSVRPPGTQGTFGISL*ESLSLGE AAGTELNVLQLRGK*DNHSSSLRLHQHCAGYHG RPRQPHLSAQAE*FRGSPGADTCAPHE*CPLEA GTPLTSPLQSYRCTPTLRCVFNVKILISTL*KQM PP*MLTCEITTTRKNKSGH*ASYEGPREHTNPA RPPLAPPGTSRTCGAPERGHFPPGREGDQGNSE RAASISLPGEEIRATCTHCVEPGREVRNQPTGPA PLPGIT**TTCFDIM*T*ARRDDSDLTK*HLSI RFAITPYPRNRTIHFIDQDDHMEGGTEAAVWAA DFLCGVQRRKRTSIPPFPQHSSILDRWYSPKALP EGTRPTERTE*CQNIAYVSTWYCNEYLL*YSYH FFSKITSLYLEFN*SK*IYLNIGSICLLVISNS LCLKRNLRCEIYKYI*LCHIKLLI

Frame 1

PPAASRAAMD*APPARPRGWGRRSRCCCCYCCC CRHASCLPPLRPSPAAGSSRGVWAACSRRASAE RPRPV*TMECLEGARRFRQWTFTATRCRPWPCSA CAWRCRSFPAQVSRGRMTILSM*WTRNLQTSRK PT*GVLKHPAQPGPQNTALAARGGTVGRAVLPW PTPSDATCPSWRPCPRPQPQTCSPGPIRRRTDPP LRVMTASPRAS*PMWPTRLR*PTLPGPGPSSAR TSCRGPSASSSQMSSALRWTVVWTDTI*WRPSV PMLPRGPQLPPGRAAWSHSTFCVHPQECPGLCWH QPPPRSGLHLWEIPKTPPAQAMEHGFIPS*RTC RGSRLR*GA*VAWSWTAWLS*WLA*CKAWTME* LEAALGERPWESLENRRMAPRPPSVETAFQMTEC RTTMIDFTKRSIV*VPHSGASCRTTGLDSYLEP SPLQGPSTWRGRSPSTLSLPCLQKRRLPEWRTS RARRIPKICWGSSRIRSPGPLRLGSSKTRCLGPR RRSRAFQRVLRRPSATACNWRSSLPRKRRGATS *QTERFSDQQ*PSK*APMSKT*PLRMWRRPQLT TKTNWRKPLD*KFFKPESGRKANSSSCLLRRSKK TPPSSSRSPWSPSPASWASSWPLASSTASAIAL STG*RRSSRD*GATQVQMPLPPTRSCAASVWPR GHQTDLRARTRHASAASHPSSATGRSPAPPHAAA PHPGPRSLCSPTWTSPPAT*SCPTWRTT*RTRT GWRRSGKRCAPTRRSPTARSWPRGRRTCPRTAP WPC*PMTTPGSC*RRRTATATQTTSTLAPSWITT RGTPRTSPPRDRCPPPWLTFGRWCGRAAAW*SS C*HPSRRTASGSATTTGRMKAPISTTSMR*TWS PSTSGVRTSW*GASI*RTCRPTRRAP*RSSTS*V GMTEESLPPQGPSWTSAEK*TSATGAVLVQ*LF IAVTVQAGAAPTS*STWFSTRWPKVLKRLISQR PWST*GTRDPAWSRRRSSLSSR*QPWLRR*TPSS RPFPSERQPQGPQGSPHPTDVVRNHDLTLIVCL LL*LHSNRALSSPVVSAV*QLKVYFCLIKQ**R EICGKIQLRVEGNRFINFHLLKKNTFS*STRSPS WLKLC*QCSSQHVRGGFQEECACHLPLSGGWIH CAGVAGEAGSTQ*GRPAHKARLAFLFERVYHWE KPQGQN*TSCSFGASETITAPRCVSINTAPGTMD GPVSHTCQPKQSDSGAPRGQTPVHPMSSAHLRL ALP*PHLCKVTDAPQH*DVFLMLKY*FLRYENR CPRECLPVR*PQPGRTNLGIEQAMRVPGSTRTLP GPRWLLQARPGPVGPQRGDISLLGEKEIRATRR GLRAFPSRERRSGRPARTA*SLEGK*ETSRPAL PLFPGSLNEPRVLTSCKPKHVEMIRI*QNNI*VS DSPSPPTPEIGQFTSLTKMITWKAAQRQLCGLQ ISCVGFSVENAPPSRPSHSIPPS*IDGTLQRPY QREHGLLSGQNDAKILLMSLHGIVMNICFNIAII SFPKLLLSIWNLINRNEFI*I*EAYAYL*FLTP YV*RETSGVRYTNIFNCVILNF*

Frame 2

LPPPPARPWTERRRPGRGDGAAAPAAAAATAAA AATRPACRPFVRPPRPAAPGASGLPARGGPLRS VRGLCERWSVWKVPEGSGNGLLPLRGVARGPAA PARGVAEAFRHRFHVAG*LYSVCDGPGTCRPPEN LPEAS*SIQPSQALKTQRWQREEVQSGGRCCPG QRPPTPPALPGGPVPGPSLRRARQDPYGAGQTP R*G**PLLREHPDLCGPHVCADLPSRVPDPAPRG PPAADPRPAPAR*AQP*GGQWCGQTPSDGGPQC LCCPEAPSSPRGGQPGATVPSACTLKNAQAFAG TSRPPEVAFTSGRFRRPLQHRRWSTDSYPPEGPA EAAG*GEGPEWPGAGRHG*ADGWPDARRGPWSS SRQPWESGPGRVWRTGGWPQGHPPWRQLSR*RS AGRR**TLPRGPSSECHTRGPPAGPRVSTLTWSP PLCKAPRHGEEEVRAP*VFPVFRRGDCRSGERQ EPDVFQRSAGAAAAFGARGRCVWGAPKPDAWAL EGGAEPSSGCSGGPQRRPAIGGPAFRGRGAGLHR DRQRGSRTSSDLQSERQCPKRDH*GCGEGHS*Q QRQTGGNLWTENSSNRSRVEKQTQVPASSGGAR RLHQVHRAHPGLPRLHPGRPPGLWPHLLPPP*LS AQAEGEALGTRGRPRCRCHCRLPGAVPPAYGHA ATRPT*GPAHVTHQQRLIPVQRRADPQPLRTQQ RLILVRGACAVQHGHLHRPHDPVLHGGPPEEQEP AGEGVGSAVRLPGGAQQLVRGPEGGERAQEPLP GRADL*PLPGPAEGGEQPQPLRLHQR*PHHGSR PEEPRVHRHPGTAARHRG*LLADGVGERLRGDRH ADTPRGERRPAVLPLLAG*RLQSLPHL*GEPGL RAHLV*GLPGEELLSEEPADQRDAHRDAVPLPE LV*PRSPFLLKVPPGLPQKSKQVLQGPFLSNNCS LQ*RCRPERHLRPDRHGSQQDGQRC*RD*YRSD PGALEGPETRHGPDEGAV*VRADSRG*GGERHP QGPSPVSGSLRGLRGAPTPRMLSGIMI*L*LCVF YYNCIVIGPLALP*SAQFSS*KCIFV*SNNNKE RFVEKSSYGWRGIGSSIFTCLKKILFLKAPVHL LG*SCVNNAVASTFEAVSRKSVLVICHFREGGST VQEWPGKLAALSEAARHTRHVWHFSLREFIIGR SRRDRTERPAASGQVRQSQLLAASPSTLRRVPW TAPSATPVSPSRVIQGLPGGRHLCTP*VVPT*GW HSPDLTFAKLQMHPNIEMCF*C*NIDFYVMKTD APVNAYL*DNHNQEEQIWALSKL*GSPGAHEPC QAPAGSSRHVPDLWGPREGTFPSWERRRSGQLGE GCEHFPPGRGDQGDLHALRRAWKGSEKPADRPC PSSRDHLMNHVF*HHVNLST*R*FGFDKITFEY PIRHHPLPQK*DNSLH*PR*SHGRRHRGSCVGCR FPVWGSA*KTHLHPALPTAFLHLR*MVLSKGPT RGNTAY*ADRMMPKYCLCLYMVL**ISALI*LS FLFQNYFSLSGI*LIEMNLSEYRKHMPTCNF*LL MFEEKPPV*DIQIYLIVSY*TSD

Sequence NM_002847

GCCTCCCGCCGCCTCCCGCGCGGCCATGGACTGAGCGCCGCCGGCCAGGCCGCGGGGATGGGGCCGCCGCTCCCGCTGCTGCTGCTGCTACTGCTGCTGC TGCCGCCACGCGTCCTGCCTGCCGCCCCTTCGTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGGCTGCCTGCTCGAGGAGGGCCTCTGCGGAGC GTCCGAGGCCTGTGTGAACGATGGAGTGTTTGGAAGGTGCCAGAAGGTTCCGGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAGCGC CTGCGCGTGGCGTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGATGACTATACTCAGTATGTGATGGACCAGGAACTTGCAGACCTCCCGAAAA CCTACCTGAGGCGTCCTGAAGCATCCAGCCCAGCCAGGCCCTCAAAACACAGCGTTGGCAGCGAGAGGAGGTACAGTCGGGAGGGCGGTGCTGCCCTGGC CAACGCCCTCCGACGCCACCTGCCCTTCCTGGAGGCCCTGTCCCAGGCCCCAGCCTCAGACGTGCTCGCCAGGACCCATACGGCGCAGGACAGACCCCCC GCTGAGGGTGATGACCGCTTCTCCGAGAGCATCCTGACCTATGTGGCCCACACGTCTGCGCTGACCTACCCTCCCGGGTCCCGGACCCAGCTCCGCGAGG ACCTCCTGCCGCGGACCCTCGGCCAGCTCCAGCCAGATGAGCTCAGCCCTAAGGTGGACAGTGGTGTGGACAGACACCATCTGATGGCGGCCCTCAGTGC CTATGCTGCCCAGAGGCCCCCAGCTCCCCCCGGGGAGGGCAGCCTGGAGCCACAGTACCTTCTGCGTGCACCCTCAAGAATGCCCAGGCCTTTGCTGGCA CCAGCCGCCCCCCAGAAGTGGCCTTCACCTCTGGGAGATTCCGAAGACCCCTCCAGCACAGGCGATGGAGCACGGATTCATACCCTCCTGAAGGACCTGC AGAGGCAGCCGGCTGAGGTGAGGGGCCTGAGTGGCCTGGAGCTGGACGGCATGGCTGAGCTGATGGCTGGCCTGATGCAAGGCGTGGACCATGGAGTAGC TCGAGGCAGCCCTGGGAGAGCGGCCCTGGGAGAGTCTGGAGAACAGGCGGATGGCCCCAAGGCCACCCTCCGTGGAGACAGCTTTCCAGATGACGGAGTG CAGGACGACGATGATAGACTTTACCAAGAGGTCCATCGTCTGAGTGCCACACTCGGGGGCCTCCTGCAGGACCACGGGTCTCGACTCTTACCTGGAGCCC TCCCCTTTGCAAGGCCCCTCGACATGGAGAGGAAGAAGTCCGAGCACCCTGAGTCTTCCCTGTCTTCAGAAGAGGAGACTGCCGGAGTGGAGAACGTCAA GAGCCAGACGTATTCCAAAGATCTGCTGGGGCAGCAGCCGCATTCGGAGCCCGGGGCCGCTGCGTTTGGGGAGCTCCAAAACCAGATGCCTGGGCCCTCG AAGGAGGAGCAGAGCCTTCCAGCGGGTGCTCAGGAGGCCCTCAGCGACGGCCTGCAATTGGAGGTCCAGCCTTCCGAGGAAGAGGCGCGGGGCTACATCG TGACAGACAGAGACCCCCTGCGCCCCGAGGAAGGAAGGCGGCTGGTGGAGGACGTCGCCCGCCTCCTGCAGGTGCCCAGCAGTGCGTTCGCTGACGTGGA GGTTCTCGGACCAGCAGTGACCTTCAAAGTGAGCGCCAATGTCCAAAACGTGACCACTGAGGATGTGGAGAAGGCCACAGTTGACAACAAAGACAAACTG GAGGAAACCTCTGGACTGAAAATTCTTCAAACCGGAGTCGGGTCGAAAAGCAAACTCAAGTTCCTGCCTCCTCAGGCGGAGCAAGAAGACTCCACCAAGT TCATCGCGCTCACCCTGGTCTCCCTCGCCTGCATCCTGGGCGTCCTCCTGGCCTCTGGCCTCATCTACTGCCTCCGCCATAGCTCTCAGCACAGGCTGAA GGAGAAGCTCTCGGGACTAGGGGGCGACCCAGGTGCAGATGCCACTGCCGCCTACCAGGAGCTGTGCCGCCAGCGTATGGCCACGCGGCCACCAGACCGA CCTGAGGGCCCGCACACGTCACGCATCAGCAGCGTCTCATCCCAGTTCAGCGACGGGCCGATCCCCAGCCCCTCCGCACGCAGCAGCGCCTCATCCTGGT CCGAGGAGCCTGTGCAGTCCAACATGGACATCTCCACCGGCCACATGATCCTGTCCTACATGGAGGACCACCTGAAGAACAAGAACCGGCTGGAGAAGGA GTGGGAAGCGCTGTGCGCCTACCAGGCGGAGCCCAACAGCTCGTTCGTGGCCCAGAGGGAGGAGAACGTGCCCAAGAACCGCTCCCTGGCCGTGCTGACC TATGACCACTCCCGGGTCCTGCTGAAGGCGGAGAACAGCCACAGCCACTCAGACTACATCAACGCTAGCCCCATCATGGATCACGACCCGAGGAACCCCG CGTACATCGCCACCCAGGGACCGCTGCCCGCCACCGTGGCTGACTTTTGGCAGATGGTGTGGGAGAGCGGCTGCGTGGTGATCGTCATGCTGACACCCCT CGCGGAGAACGGCGTCCGGCAGTGCTACCACTACTGGCCGGATGAAGGCTCCAATCTCTACCACATCTATGAGGTGAACCTGGTCTCCGAGCACATCTGG TGTGAGGACTTCCTGGTGAGGAGCTTCTATCTGAAGAACCTGCAGACCAACGAGACGCGCACCGTGACGCAGTTCCACTTCCTGAGTTGGTATGACCGAG GAGTCCCTTCCTCCTCAAGGTCCCTCCTGGACTTCCGCAGAAAAGTAAACAAGTGCTACAGGGGCCGTTCTTGTCCAATAATTGTTCATTGCAGTGACGG TGCAGGCCGGAGCGGCACCTACGTCCTGATCGACATGGTTCTCAACAAGATGGCCAAAGGTGCTAAAGAGATTGATATCGCAGCGACCCTGGAGCACTTG AGGGACCAGAGACCCGGCATGGTCCAGACGAAGGAGCAGTTTGAGTTCGCGCTGACAGCCGTGGCTGAGGAGGTGAACGCCATCCTCAAGGCCCTTCCCC AGTGAGCGGCAGCCTCAGGGGCCTCAGGGGAGCCCCCACCCCACGGATGTTGTCAGGAATCATGATCTGACTTTAATTGTGTGTCTTCTATTATAACTGC ATAGTAATAGGGCCCTTAGCTCTCCCGTAGTCAGCGCAGTTTAGCAGTTAAAAGTGTATTTTTGTTTAATCAAACAATAATAAAGAGAGATTTGTGGAAA AATCCAGTTACGGGTGGAGGGGAATCGGTTCATCAATTTTCACTTGCTTAAAAAAAATACTTTTTCTTAAAGCACCCGTTCACCTTCTTGGTTGAAGTTG TGTTAACAATGCAGTAGCCAGCACGTTCGAGGCGGTTTCCAGGAAGAGTGTGCTTGTCATCTGCCACTTTCGGGAGGGTGGATCCACTGTGCAGGAGTGG CCGGGGAAGCTGGCAGCACTCAGTGAGGCCGCCCGGCACACAAGGCACGTTTGGCATTTCTCTTTGAGAGAGTTTATCATTGGGAGAAGCCGCAGGGACA GAACTGAACGTCCTGCAGCTTCGGGGCAAGTGAGACAATCACAGCTCCTCGCTGCGTCTCCATCAACACTGCGCCGGGTACCATGGACGGCCCCGTCAGC CACACCTGTCAGCCCAAGCAGAGTGATTCAGGGGCTCCCCGGGGGCAGACACCTGTGCACCCCATGAGTAGTGCCCACTTGAGGCTGGCACTCCCCTGAC CTCACCTTTGCAAAGTTACAGATGCACCCCAACATTGAGATGTGTTTTTAATGTTAAAATATTGATTTCTACGTTATGAAAACAGATGCCCCCGTGAATG CTTACCTGTGAGATAACCACAACCAGGAAGAACAAATCTGGGCATTGAGCAAGCTATGAGGGTCCCCGGGAGCACACGAACCCTGCCAGGCCCCCGCTGG CTCCTCCAGGCACGTCCCGGACCTGTGGGGCCCCAGAGAGGGGACATTTCCCTCCTGGGAGAGAAGGAGATCAGGGCAACTCGGAGAGGGCTGCGAGCAT TTCCCTCCCGGGAGAGGAGATCAGGGCGACCTGCACGCACTGCGTAGAGCCTGGAAGGGAAGTGAGAAACCAGCCGACCGGCCCTGCCCCTCTTCCCGGG ATCACTTAATGAACCACGTGTTTTGACATCATGTAAACCTAAGCACGTAGAGATGATTCGGATTTGACAAAATAACATTTGAGTATCCGATTCGCCATCA CCCCCTACCCCAGAAATAGGACAATTCACTTCATTGACCAAGATGATCACATGGAAGGCGGCACAGAGGCAGCTGTGTGGGCTGCAGATTTCCTGTGTGG GGTTCAGCGTAGAAAACGCACCTCCATCCCGCCCTTCCCACAGCATTCCTCCATCTTAGATAGATGGTACTCTCCAAAGGCCCTACCAGAGGGAACACGG CCTACTGAGCGGACAGAATGATGCCAAAATATTGCTTATGTCTCTACATGGTATTGTAATGAATATCTGCTTTAATATAGCTATCATTTCTTTTCCAAAA TTACTTCTCTCTATCTGGAATTTAATTAATCGAAATGAATTTATCTGAATATAGGAAGCATATGCCTACTTGTAATTTCTAACTCCTTATGTTTGAAGAG AAACCTCCGGTGTGAGATATACAAATATATTTAATTGTGTCATATTAAACTTCTGATT

refseq_PTPRN2.F4 (forward primer)
refseq_PTPRN2.R4 (reverse primer)
Single exon skipping

Frame 0

ASRRLPRGHGLSAAGQAAGMGPPLPLLLLLLLL LPPRVLPAAPSSVPRGRQLPGRLGCLLEEGLCGA SEACVNDGVFGRCQKVPAMDFYRYEVSPVALQR LRVALQKLSGTGFTWQDDYTQYVMDQELADLPK TYLRRPEASSPARPSKHSVGSERRYSREGGAALA NALRRHLPFLEALSQAPASDVLARTHTAQDRPP AEGDDRFSESILTYVAHTSALTYPPGSRTQLRE DLLPRTLGQLQPDELSPKVDSGVDRHHLMAALSA YAAQRPPAPPGEGSLEPQYLLRAPSRMPRPLLA PAAPQKWPSPLGDSEDPSSTGDGARIHTLLKDL QRQPAEVRGLSGLELDGMAELMAGLMQGVDHGVA RGSPGRAALGESGEQADGPKATLRGDSFPDDGV QDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGA LPFARPLDMERKKSEHPESSLSSEEETAGVENVK SQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPS KEEQSLPAGAQEALSDGLQLEVQPSEEEARGYI VTDRDPLRPEEGRRLVEDVARLLQVPSSAFADVE VLGPAVTFKVSANVQNVTTEDVEKATVDNKDKL EETSGLKILQTGVGSKSKLKFLPPQAEQEDSTK FIALTLVSLACILGVLLASGLIYCLRHSSQHRLK EKLSGLGGDPGADATAAYQELCRQRMATRPPDR PEGPHTSRISSVSSQFSDGPIPSPSARSSASSW SEEPVQSNMDISTGHMILSYMEDHLKNKNRLEKE WEALCAYQAEPNSSFVAQREENVPKNRSLAVLT YDHSRVLLKAENSHSHSDYINASPIMDHDPRNP AYIATQGPLPATVADFWQMVWESGCVVIVMLTPL AENGVRQCYHYWPDEGSNLYHIYEVNLVSEHIW CEDFLVRSFYLKNLQTNETRTVTQFHFLSWYDR GVPSSSRSLLDFRRKVNKCYRGRSCPIIVHCSDG AGRSGTYVLIDMVLNKMAKGAKEIDIAATLEHL RDQRPGMVQTKEQFEFALTAVAEEVNAILKALP Q*AAASGASGEPPPHGCCQES*SDFNCVSSIITA ***GP*LSRSQRSLAVKSVFLFNQTIIKRDLWK NPVTGGGESVHQFSLA*KKYFFLKHPFTFLVEV VLTMQ*PARSRRFPGRVCLSSATFGRVDPLCRSG RGSWQHSVRPPGTQGTFGISL*ESLSLGEAAGT ELNVLQLRGK*DNHSSSLRLHQHCAGYHGRPRQ PHLSAQAE*FRGSPGADTCAPHE*CPLEAGTPLT SPLQSYRCTPTLRCVFNVKILISTL*KQMPP*M LTCEITTTRKNKSGH*ASYEGPREHTNPARPPL APPGTSRTCGAPERGHFPPGREGDQGNSERAASI SLPGEEIRATCTHCVEPGREVRNQPTGPAPLPG IT**TTCFDIM*T*ARRDDSDLTK*HLSIRFAI TPYPRNRTIHFIDQDDHMEGGTEAAVWAADFLCG VQRRKRTSIPPFPQHSSILDRWYSPKALPEGTR PTERTE*CQNIAYVSTWYCNEYLL*YSYHFFSK ITSLYLEFN*SK*IYLNIGSICLLVISNSLCLKR NLRCEIYKYI*LCHIKLLI

Frame 1

PPAASRAAMD*APPARPRGWGRRSRCCCCYCCC CRHASCLPPLRPSPAAGSSRGVWAACSRRASAE RPRPV*TMECLEGARRFRQWTFTATRCRPWPCSA CAWRCRSFPAQVSRGRMTILSM*WTRNLQTSRK PT*GVLKHPAQPGPQNTALAARGGTVGRAVLPW PTPSDATCPSWRPCPRPQPQTCSPGPIRRRTDPP LRVMTASPRAS*PMWPTRLR*PTLPGPGPSSAR TSCRGPSASSSQMSSALRWTVVWTDTI*WRPSV PMLPRGPQLPPGRAAWSHSTFCVHPQECPGLCWH QPPPRSGLHLWEIPKTPPAQAMEHGFIPS*RTC RGSRLR*GA*VAWSWTAWLS*WLA*CKAWTME* LEAALGERPWESLENRRMAPRPPSVETAFQMTEC RTTMIDFTKRSIV*VPHSGASCRTTGLDSYLEP SPLQGPSTWRGRSPSTLSLPCLQKRRLPEWRTS RARRIPKICWGSSRIRSPGPLRLGSSKTRCLGPR RRSRAFQRVLRRPSATACNWRSSLPRKRRGATS *QTETPCAPRKEGGWWRTSPASCRCPAVRSLTW RFSDQQ*PSK*APMSKT*PLRMWRRPQLTTKTNW RKPLD*KFFKPESGRKANSSSCLLRRSKKTPPS SSRSPWSPSPASWASSWPLASSTASAIALSTG* RRSSRD*GATQVQMPLPPTRSCAASVWPRGHQTD LRARTRHASAASHPSSATGRSPAPPHAAAPHPG PRSLCSPTWTSPPAT*SCPTWRTT*RTRTGWRR SGKRCAPTRRSPTARSWPRGRRTCPRTAPWPC*P MTTPGSC*RRRTATATQTTSTLAPSWITTRGTP RTSPPRDRCPPPWLTFGRWCGRAAAW*SSC*HP SRRTASGSATTTGRMKAPISTTSMR*TWSPSTSG VRTSW*GASI*RTCRPTRRAP*RSSTS*VGMTE ESLPPQGPSWTSAEK*TSATGAVLVQ*LFIAVT VQAGAAPTS*STWFSTRWPKVLKRLISQRPWST* GTRDPAWSRRRSSLSSR*QPWLRR*TPSSRPFP SERQPQGPQGSPHPTDVVRNHDLTLIVCLLL*L HSNRALSSPVVSAV*QLKVYFCLIKQ**REICGK IQLRVEGNRFINFHLLKKNTFS*STRSPSWLKL C*QCSSQHVRGGFQEECACHLPLSGGWIHCAGV AGEAGSTQ*GRPAHKARLAFLFERVYHWEKPQGQ N*TSCSFGASETITAPRCVSINTAPGTMDGPVS HTCQPKQSDSGAPRGQTPVHPMSSAHLRLALP* PHLCKVTDAPQH*DVFLMLKY*FLRYENRCPREC LPVR*PQPGRTNLGIEQAMRVPGSTRTLPGPRW LLQARPGPVGPQRGDISLLGEKEIRATRRGLRA FPSRERRSGRPARTA*SLEGK*ETSRPALPLFPG SLNEPRVLTSCKPKHVEMIRI*QNNI*VSDSPS PPTPEIGQFTSLTKMITWKAAQRQLCGLQISCV GFSVENAPPSRPSHSIPPS*IDGTLQRPYQREHG LLSGQNDAKILLMSLHGIVMNICFNIAIISFPK LLLSIWNLINRNEFI*I*EAYAYL*FLTPYV*R ETSGVRYTNIFNCVILNF*

Frame 2

LPPPPARPWTERRRPGRGDGAAAPAAAAATAAA AATRPACRPFVRPPRPAAPGASGLPARGGPLRS VRGLCERWSVWKVPEGSGNGLLPLRGVARGPAA PARGVAEAFRHRFHVAG*LYSVCDGPGTCRPPEN LPEAS*SIQPSQALKTQRWQREEVQSGGRCCPG QRPPTPPALPGGPVPGPSLRRARQDPYGAGQTP R*G**PLLREHPDLCGPHVCADLPSRVPDPAPRG PPAADPRPAPAR*AQP*GGQWCGQTPSDGGPQC LCCPEAPSSPRGGQPGATVPSACTLKNAQAFAG TSRPPEVAFTSGRFRRPLQHRRWSTDSYPPEGPA EAAG*GEGPEWPGAGRHG*ADGWPDARRGPWSS SRQPWESGPGRVWRTGGWPQGHPPWRQLSR*RS AGRR**TLPRGPSSECHTRGPPAGPRVSTLTWSP PLCKAPRHGEEEVRAP*VFPVFRRGDCRSGERQ EPDVFQRSAGAAAAFGARGRCVWGAPKPDAWAL EGGAEPSSGCSGGPQRRPAIGGPAFRGRGAGLHR DRQRPPAPRGRKAAGGGRRPPPAGAQQCVR*RG GSRTSSDLQSERQCPKRDH*GCGEGHS*QQRQT GGNLWTENSSNRSRVEKQTQVPASSGGARRLHQV HRAHPGLPRLHPGRPPGLWPHLLPPP*LSAQAE GEALGTRGRPRCRCHCRLPGAVPPAYGHAATRP T*GPAHVTHQQRLIPVQRRADPQPLRTQQRLILV RGACAVQHGHLHRPHDPVLHGGPPEEQEPAGEG VGSAVRLPGGAQQLVRGPEGGERAQEPLPGRAD L*PLPGPAEGGEQPQPLRLHQR*PHHGSRPEEPR VHRHPGTAARHRG*LLADGVGERLRGDRHADTP RGERRPAVLPLLAG*RLQSLPHL*GEPGLRAHL V*GLPGEELLSEEPADQRDAHRDAVPLPELV*PR SPFLLKVPPGLPQKSKQVLQGPFLSNNCSLQ*R CRPERHLRPDRHGSQQDGQRC*RD*YRSDPGAL EGPETRHGPDEGAV*VRADSRG*GGERHPQGPSP VSGSLRGLRGAPTPRMLSGIMI*L*LCVFYYNC IVIGPLALP*SAQFSS*KCIFV*SNNNKERFVE KSSYGWRGIGSSIFTCLKKILFLKAPVHLLG*SC VNNAVASTFEAVSRKSVLVICHFREGGSTVQEW PGKLAALSEAARHTRHVWHFSLREFIIGRSRRD RTERPAASGQVRQSQLLAASPSTLRRVPWTAPSA TPVSPSRVIQGLPGGRHLCTP*VVPT*GWHSPD LTFAKLQMHPNIEMCF*C*NIDFYVMKTDAPVN AYL*DNHNQEEQIWALSKL*GSPGAHEPCQAPAG SSRHVPDLWGPREGTFPSWERRRSGQLGEGCEH FPPGRGDQGDLHALRRAWKGSEKPADRPCPSSR DHLMNHVF*HHVNLST*R*FGFDKITFEYPIRHH PLPQK*DNSLH*PR*SHGRRHRGSCVGCRFPVW GSA*KTHLHPALPTAFLHLR*MVLSKGPTRGNT AY*ADRMMPKYCLCLYMVL**ISALI*LSFLFQN YFSLSGI*LIEMNLSEYRKHMPTCNF*LLMFEE KPPV*DIQIYLIVSY*TSD

Sequence NM_130842

GCCTCCCGCCGCCTCCCGCGCGGCCATGGACTGAGCGCCGCCGGCCAGGCCGCGGGGATGGGGCCGCCGCTCCCGCTGCTGCTGCTGCTACTGCTGCTGC TGCCGCCACGCGTCCTGCCTGCCGCCCCTTCGTCCGTCCCCCGCGGCCGGCAGCTCCCGGGGCGTCTGGATGGAGTGTTTGGAAGGTGCCAGAAGGTTCC GGCAATGGACTTTTACCGCTACGAGGTGTCGCCCGTGGCCCTGCAGCGCCTGCGCGTGGCGTTGCAGAAGCTTTCCGGCACAGGTTTCACGTGGCAGGAT GACTATACTCAGTATGTGATGGACCAGGAACTTGCAGACCTCCCGAAAACCTACCTGAGGCGTCCTGAAGCATCCAGCCCAGCCAGGCCCTCAAAACACA GCGTTGGCAGCGAGAGGAGGTACAGTCGGGAGGGCGGTGCTGCCCTGGCCAACGCCCTCCGACGCCACCTGCCCTTCCTGGAGGCCCTGTCCCAGGCCCC AGCCTCAGACGTGCTCGCCAGGACCCATACGGCGCAGGACAGACCCCCCGCTGAGGGTGATGACCGCTTCTCCGAGAGCATCCTGACCTATGTGGCCCAC ACGTCTGCGCTGACCTACCCTCCCGGGTCCCGGACCCAGCTCCGCGAGGACCTCCTGCCGCGGACCCTCGGCCAGCTCCAGCCAGATGAGCTCAGCCCTA AGGTGGACAGTGGTGTGGACAGACACCATCTGATGGCGGCCCTCAGTGCCTATGCTGCCCAGAGGCCCCCAGCTCCCCCCGGGGAGGGCAGCCTGGAGCC ACAGTACCTTCTGCGTGCACCCTCAAGAATGCCCAGGCCTTTGCTGGCACCAGCCGCCCCCCAGAAGTGGCCTTCACCTCTGGGAGATTCCGAAGACCCC TCCAGCACAGGCGATGGAGCACGGATTCATACCCTCCTGAAGGACCTGCAGAGGCAGCCGGCTGAGGTGAGGGGCCTGAGTGGCCTGGAGCTGGACGGCA TGGCTGAGCTGATGGCTGGCCTGATGCAAGGCGTGGACCATGGAGTAGCTCGAGGCAGCCCTGGGAGAGCGGCCCTGGGAGAGTCTGGAGAACAGGCGGA TGGCCCCAAGGCCACCCTCCGTGGAGACAGCTTTCCAGATGACGGAGTGCAGGACGACGATGATAGACTTTACCAAGAGGTCCATCGTCTGAGTGCCACA CTCGGGGGCCTCCTGCAGGACCACGGGTCTCGACTCTTACCTGGAGCCCTCCCCTTTGCAAGGCCCCTCGACATGGAGAGGAAGAAGTCCGAGCACCCTG AGTCTTCCCTGTCTTCAGAAGAGGAGACTGCCGGAGTGGAGAACGTCAAGAGCCAGACGTATTCCAAAGATCTGCTGGGGCAGCAGCCGCATTCGGAGCC CGGGGCCGCTGCGTTTGGGGAGCTCCAAAACCAGATGCCTGGGCCCTCGAAGGAGGAGCAGAGCCTTCCAGCGGGTGCTCAGGAGGCCCTCAGCGACGGC CTGCAATTGGAGGTCCAGCCTTCCGAGGAAGAGGCGCGGGGCTACATCGTGACAGACAGAGACCCCCTGCGCCCCGAGGAAGGAAGGCGGCTGGTGGAGG ACGTCGCCCGCCTCCTGCAGGTGCCCAGCAGTGCGTTCGCTGACGTGGAGGTTCTCGGACCAGCAGTGACCTTCAAAGTGAGCGCCAATGTCCAAAACGT GACCACTGAGGATGTGGAGAAGGCCACAGTTGACAACAAAGACAAACTGGAGGAAACCTCTGGACTGAAAATTCTTCAAACCGGAGTCGGGTCGAAAAGC AAACTCAAGTTCCTGCCTCCTCAGGCGGAGCAAGAAGACTCCACCAAGTTCATCGCGCTCACCCTGGTCTCCCTCGCCTGCATCCTGGGCGTCCTCCTGG CCTCTGGCCTCATCTACTGCCTCCGCCATAGCTCTCAGCACAGGCTGAAGGAGAAGCTCTCGGGACTAGGGGGCGACCCAGGTGCAGATGCCACTGCCGC CTACCAGGAGCTGTGCCGCCAGCGTATGGCCACGCGGCCACCAGACCGACCTGAGGGCCCGCACACGTCACGCATCAGCAGCGTCTCATCCCAGTTCAGC GACGGGCCGATCCCCAGCCCCTCCGCACGCAGCAGCGCCTCATCCTGGTCCGAGGAGCCTGTGCAGTCCAACATGGACATCTCCACCGGCCACATGATCC TGTCCTACATGGAGGACCACCTGAAGAACAAGAACCGGCTGGAGAAGGAGTGGGAAGCGCTGTGCGCCTACCAGGCGGAGCCCAACAGCTCGTTCGTGGC CCAGAGGGAGGAGAACGTGCCCAAGAACCGCTCCCTGGCCGTGCTGACCTATGACCACTCCCGGGTCCTGCTGAAGGCGGAGAACAGCCACAGCCACTCA GACTACATCAACGCTAGCCCCATCATGGATCACGACCCGAGGAACCCCGCGTACATCGCCACCCAGGGACCGCTGCCCGCCACCGTGGCTGACTTTTGGC AGATGGTGTGGGAGAGCGGCTGCGTGGTGATCGTCATGCTGACACCCCTCGCGGAGAACGGCGTCCGGCAGTGCTACCACTACTGGCCGGATGAAGGCTC CAATCTCTACCACATCTATGAGGTGAACCTGGTCTCCGAGCACATCTGGTGTGAGGACTTCCTGGTGAGGAGCTTCTATCTGAAGAACCTGCAGACCAAC GAGACGCGCACCGTGACGCAGTTCCACTTCCTGAGTTGGTATGACCGAGGAGTCCCTTCCTCCTCAAGGTCCCTCCTGGACTTCCGCAGAAAAGTAAACA AGTGCTACAGGGGCCGTTCTTGTCCAATAATTGTTCATTGCAGTGACGGTGCAGGCCGGAGCGGCACCTACGTCCTGATCGACATGGTTCTCAACAAGAT GGCCAAAGGTGCTAAAGAGATTGATATCGCAGCGACCCTGGAGCACTTGAGGGACCAGAGACCCGGCATGGTCCAGACGAAGGAGCAGTTTGAGTTCGCG CTGACAGCCGTGGCTGAGGAGGTGAACGCCATCCTCAAGGCCCTTCCCCAGTGAGCGGCAGCCTCAGGGGCCTCAGGGGAGCCCCCACCCCACGGATGTT GTCAGGAATCATGATCTGACTTTAATTGTGTGTCTTCTATTATAACTGCATAGTAATAGGGCCCTTAGCTCTCCCGTAGTCAGCGCAGTTTAGCAGTTAA AAGTGTATTTTTGTTTAATCAAACAATAATAAAGAGAGATTTGTGGAAAAATCCAGTTACGGGTGGAGGGGAATCGGTTCATCAATTTTCACTTGCTTAA AAAAAATACTTTTTCTTAAAGCACCCGTTCACCTTCTTGGTTGAAGTTGTGTTAACAATGCAGTAGCCAGCACGTTCGAGGCGGTTTCCAGGAAGAGTGT GCTTGTCATCTGCCACTTTCGGGAGGGTGGATCCACTGTGCAGGAGTGGCCGGGGAAGCTGGCAGCACTCAGTGAGGCCGCCCGGCACACAAGGCACGTT TGGCATTTCTCTTTGAGAGAGTTTATCATTGGGAGAAGCCGCAGGGACAGAACTGAACGTCCTGCAGCTTCGGGGCAAGTGAGACAATCACAGCTCCTCG CTGCGTCTCCATCAACACTGCGCCGGGTACCATGGACGGCCCCGTCAGCCACACCTGTCAGCCCAAGCAGAGTGATTCAGGGGCTCCCCGGGGGCAGACA CCTGTGCACCCCATGAGTAGTGCCCACTTGAGGCTGGCACTCCCCTGACCTCACCTTTGCAAAGTTACAGATGCACCCCAACATTGAGATGTGTTTTTAA TGTTAAAATATTGATTTCTACGTTATGAAAACAGATGCCCCCGTGAATGCTTACCTGTGAGATAACCACAACCAGGAAGAACAAATCTGGGCATTGAGCA AGCTATGAGGGTCCCCGGGAGCACACGAACCCTGCCAGGCCCCCGCTGGCTCCTCCAGGCACGTCCCGGACCTGTGGGGCCCCAGAGAGGGGACATTTCC CTCCTGGGAGAGAAGGAGATCAGGGCAACTCGGAGAGGGCTGCGAGCATTTCCCTCCCGGGAGAGGAGATCAGGGCGACCTGCACGCACTGCGTAGAGCC TGGAAGGGAAGTGAGAAACCAGCCGACCGGCCCTGCCCCTCTTCCCGGGATCACTTAATGAACCACGTGTTTTGACATCATGTAAACCTAAGCACGTAGA GATGATTCGGATTTGACAAAATAACATTTGAGTATCCGATTCGCCATCACCCCCTACCCCAGAAATAGGACAATTCACTTCATTGACCAAGATGATCACA TGGAAGGCGGCACAGAGGCAGCTGTGTGGGCTGCAGATTTCCTGTGTGGGGTTCAGCGTAGAAAACGCACCTCCATCCCGCCCTTCCCACAGCATTCCTC CATCTTAGATAGATGGTACTCTCCAAAGGCCCTACCAGAGGGAACACGGCCTACTGAGCGGACAGAATGATGCCAAAATATTGCTTATGTCTCTACATGG TATTGTAATGAATATCTGCTTTAATATAGCTATCATTTCTTTTCCAAAATTACTTCTCTCTATCTGGAATTTAATTAATCGAAATGAATTTATCTGAATA TAGGAAGCATATGCCTACTTGTAATTTCTAACTCCTTATGTTTGAAGAGAAACCTCCGGTGTGAGATATACAAATATATTTAATTGTGTCATATTAAACT TCTGATT

refseq_PTPRN2.F4 (forward primer)
refseq_PTPRN2.R4 (reverse primer)
Single exon skipping

Frame 0

ASRRLPRGHGLSAAGQAAGMGPPLPLLLLLLLL LPPRVLPAAPSSVPRGRQLPGRLDGVFGRCQKVP AMDFYRYEVSPVALQRLRVALQKLSGTGFTWQD DYTQYVMDQELADLPKTYLRRPEASSPARPSKH SVGSERRYSREGGAALANALRRHLPFLEALSQAP ASDVLARTHTAQDRPPAEGDDRFSESILTYVAH TSALTYPPGSRTQLREDLLPRTLGQLQPDELSP KVDSGVDRHHLMAALSAYAAQRPPAPPGEGSLEP QYLLRAPSRMPRPLLAPAAPQKWPSPLGDSEDP SSTGDGARIHTLLKDLQRQPAEVRGLSGLELDG MAELMAGLMQGVDHGVARGSPGRAALGESGEQAD GPKATLRGDSFPDDGVQDDDDRLYQEVHRLSAT LGGLLQDHGSRLLPGALPFARPLDMERKKSEHP ESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEP GAAAFGELQNQMPGPSKEEQSLPAGAQEALSDG LQLEVQPSEEEARGYIVTDRDPLRPEEGRRLVE DVARLLQVPSSAFADVEVLGPAVTFKVSANVQNV TTEDVEKATVDNKDKLEETSGLKILQTGVGSKS KLKFLPPQAEQEDSTKFIALTLVSLACILGVLL ASGLIYCLRHSSQHRLKEKLSGLGGDPGADATAA YQELCRQRMATRPPDRPEGPHTSRISSVSSQFS DGPIPSPSARSSASSWSEEPVQSNMDISTGHMI LSYMEDHLKNKNRLEKEWEALCAYQAEPNSSFVA QREENVPKNRSLAVLTYDHSRVLLKAENSHSHS DYINASPIMDHDPRNPAYIATQGPLPATVADFW QMVWESGCVVIVMLTPLAENGVRQCYHYWPDEGS NLYHIYEVNLVSEHIWCEDFLVRSFYLKNLQTN ETRTVTQFHFLSWYDRGVPSSSRSLLDFRRKVN KCYRGRSCPIIVHCSDGAGRSGTYVLIDMVLNKM AKGAKEIDIAATLEHLRDQRPGMVQTKEQFEFA LTAVAEEVNAILKALPQ*AAASGASGEPPPHGC CQES*SDFNCVSSIITA***GP*LSRSQRSLAVK SVFLFNQTIIKRDLWKNPVTGGGESVHQFSLA* KKYFFLKHPFTFLVEVVLTMQ*PARSRRFPGRV CLSSATFGRVDPLCRSGRGSWQHSVRPPGTQGTF GISL*ESLSLGEAAGTELNVLQLRGK*DNHSSS LRLHQHCAGYHGRPRQPHLSAQAE*FRGSPGAD TCAPHE*CPLEAGTPLTSPLQSYRCTPTLRCVFN VKILISTL*KQMPP*MLTCEITTTRKNKSGH*A SYEGPREHTNPARPPLAPPGTSRTCGAPERGHF PPGREGDQGNSERAASISLPGEEIRATCTHCVEP GREVRNQPTGPAPLPGIT**TTCFDIM*T*ARR DDSDLTK*HLSIRFAITPYPRNRTIHFIDQDDH MEGGTEAAVWAADFLCGVQRRKRTSIPPFPQHSS ILDRWYSPKALPEGTRPTERTE*CQNIAYVSTW YCNEYLL*YSYHFFSKITSLYLEFN*SK*IYLN IGSICLLVISNSLCLKRNLRCEIYKYI*LCHIKL LI

Frame 1

PPAASRAAMD*APPARPRGWGRRSRCCCCYCCC CRHASCLPPLRPSPAAGSSRGVWMECLEGARRF RQWTFTATRCRPWPCSACAWRCRSFPAQVSRGRM TILSM*WTRNLQTSRKPT*GVLKHPAQPGPQNT ALAARGGTVGRAVLPWPTPSDATCPSWRPCPRP QPQTCSPGPIRRRTDPPLRVMTASPRAS*PMWPT RLR*PTLPGPGPSSARTSCRGPSASSSQMSSAL RWTVVWTDTI*WRPSVPMLPRGPQLPPGRAAWS HSTFCVHPQECPGLCWHQPPPRSGLHLWEIPKTP PAQAMEHGFIPS*RTCRGSRLR*GA*VAWSWTA WLS*WLA*CKAWTME*LEAALGERPWESLENRR MAPRPPSVETAFQMTECRTTMIDFTKRSIV*VPH SGASCRTTGLDSYLEPSPLQGPSTWRGRSPSTL SLPCLQKRRLPEWRTSRARRIPKICWGSSRIRS PGPLRLGSSKTRCLGPRRRSRAFQRVLRRPSATA CNWRSSLPRKRRGATS*QTETPCAPRKEGGWWR TSPASCRCPAVRSLTWRFSDQQ*PSK*APMSKT *PLRMWRRPQLTTKTNWRKPLD*KFFKPESGRKA NSSSCLLRRSKKTPPSSSRSPWSPSPASWASSW PLASSTASAIALSTG*RRSSRD*GATQVQMPLP PTRSCAASVWPRGHQTDLRARTRHASAASHPSSA TGRSPAPPHAAAPHPGPRSLCSPTWTSPPAT*S CPTWRTT*RTRTGWRRSGKRCAPTRRSPTARSW PRGRRTCPRTAPWPC*PMTTPGSC*RRRTATATQ TTSTLAPSWITTRGTPRTSPPRDRCPPPWLTFG RWCGRAAAW*SSC*HPSRRTASGSATTTGRMKA PISTTSMR*TWSPSTSGVRTSW*GASI*RTCRPT RRAP*RSSTS*VGMTEESLPPQGPSWTSAEK*T SATGAVLVQ*LFIAVTVQAGAAPTS*STWFSTR WPKVLKRLISQRPWST*GTRDPAWSRRRSSLSSR *QPWLRR*TPSSRPFPSERQPQGPQGSPHPTDV VRNHDLTLIVCLLL*LHSNRALSSPVVSAV*QL KVYFCLIKQ**REICGKIQLRVEGNRFINFHLLK KNTFS*STRSPSWLKLC*QCSSQHVRGGFQEEC ACHLPLSGGWIHCAGVAGEAGSTQ*GRPAHKAR LAFLFERVYHWEKPQGQN*TSCSFGASETITAPR CVSINTAPGTMDGPVSHTCQPKQSDSGAPRGQT PVHPMSSAHLRLALP*PHLCKVTDAPQH*DVFL MLKY*FLRYENRCPRECLPVR*PQPGRTNLGIEQ AMRVPGSTRTLPGPRWLLQARPGPVGPQRGDIS LLGEKEIRATRRGLRAFPSRERRSGRPARTA*S LEGK*ETSRPALPLFPGSLNEPRVLTSCKPKHVE MIRI*QNNI*VSDSPSPPTPEIGQFTSLTKMIT WKAAQRQLCGLQISCVGFSVENAPPSRPSHSIP PS*IDGTLQRPYQREHGLLSGQNDAKILLMSLHG IVMNICFNIAIISFPKLLLSIWNLINRNEFI*I *EAYAYL*FLTPYV*RETSGVRYTNIFNCVILN F*

Frame 2

LPPPPARPWTERRRPGRGDGAAAPAAAAATAAA AATRPACRPFVRPPRPAAPGASGWSVWKVPEGS GNGLLPLRGVARGPAAPARGVAEAFRHRFHVAG *LYSVCDGPGTCRPPENLPEAS*SIQPSQALKTQ RWQREEVQSGGRCCPGQRPPTPPALPGGPVPGP SLRRARQDPYGAGQTPR*G**PLLREHPDLCGP HVCADLPSRVPDPAPRGPPAADPRPAPAR*AQP* GGQWCGQTPSDGGPQCLCCPEAPSSPRGGQPGA TVPSACTLKNAQAFAGTSRPPEVAFTSGRFRRP LQHRRWSTDSYPPEGPAEAAG*GEGPEWPGAGRH G*ADGWPDARRGPWSSSRQPWESGPGRVWRTGG WPQGHPPWRQLSR*RSAGRR**TLPRGPSSECH TRGPPAGPRVSTLTWSPPLCKAPRHGEEEVRAP* VFPVFRRGDCRSGERQEPDVFQRSAGAAAAFGA RGRCVWGAPKPDAWALEGGAEPSSGCSGGPQRR PAIGGPAFRGRGAGLHRDRQRPPAPRGRKAAGGG RRPPPAGAQQCVR*RGGSRTSSDLQSERQCPKR DH*GCGEGHS*QQRQTGGNLWTENSSNRSRVEK QTQVPASSGGARRLHQVHRAHPGLPRLHPGRPPG LWPHLLPPP*LSAQAEGEALGTRGRPRCRCHCR LPGAVPPAYGHAATRPT*GPAHVTHQQRLIPVQ RRADPQPLRTQQRLILVRGACAVQHGHLHRPHDP VLHGGPPEEQEPAGEGVGSAVRLPGGAQQLVRG PEGGERAQEPLPGRADL*PLPGPAEGGEQPQPL RLHQR*PHHGSRPEEPRVHRHPGTAARHRG*LLA DGVGERLRGDRHADTPRGERRPAVLPLLAG*RL QSLPHL*GEPGLRAHLV*GLPGEELLSEEPADQ RDAHRDAVPLPELV*PRSPFLLKVPPGLPQKSKQ VLQGPFLSNNCSLQ*RCRPERHLRPDRHGSQQD GQRC*RD*YRSDPGALEGPETRHGPDEGAV*VR ADSRG*GGERHPQGPSPVSGSLRGLRGAPTPRML SGIMI*L*LCVFYYNCIVIGPLALP*SAQFSS* KCIFV*SNNNKERFVEKSSYGWRGIGSSIFTCL KKILFLKAPVHLLG*SCVNNAVASTFEAVSRKSV LVICHFREGGSTVQEWPGKLAALSEAARHTRHV WHFSLREFIIGRSRRDRTERPAASGQVRQSQLL AASPSTLRRVPWTAPSATPVSPSRVIQGLPGGRH LCTP*VVPT*GWHSPDLTFAKLQMHPNIEMCF* C*NIDFYVMKTDAPVNAYL*DNHNQEEQIWALS KL*GSPGAHEPCQAPAGSSRHVPDLWGPREGTFP SWERRRSGQLGEGCEHFPPGRGDQGDLHALRRA WKGSEKPADRPCPSSRDHLMNHVF*HHVNLST* R*FGFDKITFEYPIRHHPLPQK*DNSLH*PR*SH GRRHRGSCVGCRFPVWGSA*KTHLHPALPTAFL HLR*MVLSKGPTRGNTAY*ADRMMPKYCLCLYM VL**ISALI*LSFLFQNYFSLSGI*LIEMNLSEY RKHMPTCNF*LLMFEEKPPV*DIQIYLIVSY*T SD