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Sequences

Sequence NM_080840

GCGCTCGGACCCCGGCCGCTGCCGCCATCACTGTCGCCCGCCCAGTCGCCCCTCAGCCGCTTCCCCTCGCCATGGAGGCGAGGCCGCCGCCGCCGCCGCG GGGCTCGGAGCCGCGGGCCGGGCGGCGGCCCTGAGGGCTAGTGGCGGCCCGAAACGCCGCCGCGGAGCCGAGGCGGAGCCGCTGTCCTCGTCCCCAGCGG TCCCGCCCAACGCCCGACTCTGTGACACAACTAAAAAAAAACAAAGGTATTTATGGAATTCCACTGAGTGGTAATGGATGATGCAGTTCAAATAACTAAG GACACATGTTCAAAGAGCATAATTAACTTTTTAAAAGAAGCTAATAAGCATGGATTCCTGGTTCATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTC AGTGCCAACAATGCTACCACAGTTGCACCTTCTGTAGGAATTACAAGATTAATTAACTCATCAACGGCAGAACCAGTTAAAGAAGAGGCCAAAACTTCAA ATCCAACTTCTTCACTAACTTCTCTTTCTGTGGCACCAACATTCAGCCCAAATATAACTCTGGGACCCACCTATTTAACCACTGTCAATTCTTCAGACTC TGACAATGGGACCACAAGAACAGCAAGCACCAATTCTATAGGCATTACAATTTCACCAAATGGAACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGA ACAGAACCCTGGGAGGGGAATTCCAGCACCGCAGCAACCACTCCAGAAACTTTCCCTCCTTCAGATGAGACACCAATTATTGCGGTGATGGTGGCCCTGT CCTCTCTGCTAGTGATCGTGTTTATTATCATAGTTTTGTACATGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCTTATC CAACGGCCGCACTGAGGATGTGGAGCCCCAGAGTGTGCCACTTCTGGCCAGATCCCCAAGCACCAACAGGAAATACCCACCCCTGCCCGTGGACAAGCTG GAAGAGGAAATTAACCGGAGAATGGCAGACGACAATAAGCTCTTCAGGGAGGAATTCAACGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTG CTTCCAAGGAGGAAAACAAGGAAAAAAATCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTC TGATTACATCAATGCTTCATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGG ATGATCTGGGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTGCT GGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGGCGACATGACCAA CAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGGCATGCTCAAGTTCCTCAAGAAG GTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTACAGGTACCTTTGTCGTCATTGATGCCATGCTGG ACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGCACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTT CATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACTGGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCA GGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAAGTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGA AGAAGAACCGTGTTTTACAGATCATTCCATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTT TATTGATGGCTACCGGCAGAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCC TGCTCTATCGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTACAG TGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGATCCGGCAGTTCCA CTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCAC CCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCTGGAGCGTGTGAAAGCAGAGGGGATTTTGGATG TCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGAACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGA TGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCGTGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATAT ACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAAATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACT GATAGTCCTTTTTCCAATGTTTTATTGGGGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTT TGGTTAATACATCTTTCCCTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGA GGAAAGTGGTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTAAT AGGACCAGAGCGGTATCTCTGGCACCACACTAGGGACTATCAGGTAATAAAAGCTTTGACTCCCTGA

refseq_PTPRA.F1 (forward primer)
refseq_PTPRA.R1 (reverse primer)
Single exon skipping

Frame 0

ALGPRPLPPSLSPAQSPLSRFPSPWRRGRRRRR GARSRGPGGGPEG*WRPETPPRSRGGAAVLVPSG PAQRPTL*HN*KKTKVFMEFH*VVMDDAVQITK DTCSKSIINFLKEANKHGFLVHSCSARQWSDMC QCQQCYHSCTFCRNYKIN*LINGRTS*RRGQNFK SNFFTNFSFCGTNIQPKYNSGTHLFNHCQFFRL *QWDHKNSKHQFYRHYNFTKWNVASR*PVHGCQ NRTLGGEFQHRSNHSRNFPSFR*DTNYCGDGGPV LSASDRVYYHSFVHVKV*EIQASWEPFQFFPLI QRPH*GCGAPECATSGQIPKHQQEIPTPARGQA GRGN*PENGRRQ*ALQGGIQRSPCMSYPGHL*GC FQGGKQGKKSICKHLAL*PL*SPPDTG*RGSRF *LHQCFIHQRLPRKEQIHCCTRTKRRNGE*FLA DDLGTKHSHHRHGYQPEGEKGVQVRPVLARPRLL DLWEYSGVCRGCDCPGGLHSTEVLHPAGGRHDQ QKATAPHHSVPLYQLARLWGAFYPDRHAQVPQE GEGL*PSVCRGHRGPLQCRCRAYRYLCRH*CHAG HDAYRTEGGRVWLCEPDPGTALPDGANRYAVCL HIPSPSGALSLWRYRTGSDLSRNPPAENLQQNP RDQQQWIRGGV*EVNINQNPE*QDADWKPSSQHE EEPCFTDHSI*IQQSDHSS*AGRREYRLCERIL Y*WLPAEGLLYRQPGPSSPHN*GLLANDLGVEI LLYRDANRTGGERPGEVCPVLAI*WTGVLWRYYS GTEEGGGM*ELHRPRPPGHQHQGE*EPADPAVP LPWLA*SGHPQ*RKGHDQHHRRRAEAAAAVREP PHHRALQRRGRKDGDLLCPEHRPGACESRGDFGC LPDCQEPAATEATHGPDTGTV*VLLQGGAGVY* CILRLCQLQVSGNKGPWTRRIAFNIL*YSVLLI YPKLCIYLITVLEIGT*ASITY*VEILYVNVLAL IVLFPMFYWGIK*CDVWIDIVKSSAEKLGWIVL WLIHLSLKKINTKSIPGSSAPTKKKSTKFSELS RKVVVPVPPCTVNIPPLSPWSPPPSPPLISWGVI GPERYLWHHTRDYQVIKALTP*

Frame 1

RSDPGRCRHHCRPPSRPSAASPRHGGEAAAAAA GLGAAGRAAALRASGGPKRRRGAEAEPLSSSPA VPPNARLCDTTKKKQRYLWNSTEW*WMMQFK*LR THVQRA*LTF*KKLISMDSWFILVLLGSGLICV SANNATTVAPSVGITRLINSSTAEPVKEEAKTS NPTSSLTSLSVAPTFSPNITLGPTYLTTVNSSDS DNGTTRTASTNSIGITISPNGTWLPDNQFTDAR TEPWEGNSSTAATTPETFPPSDETPIIAVMVAL SSLLVIVFIIIVLYMLRFKKYKQAGSHSNSFRLS NGRTEDVEPQSVPLLARSPSTNRKYPPLPVDKL EEEINRRMADDNKLFREEFNALPACPIQATCEA ASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDS DYINASFINGYQEKNKFIAAQGPKEETVNDFWR MIWEQNTATIVMVTNLKERKECKCAQYWPDQGC WTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTN RKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKK VKACNPQYAGAIVVHCSAGVGRTGTFVVIDAML DMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVF IYQALLEHYLYGDTELEVTSLETHLQKIYNKIP GTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANM KKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASF IDGYRQKDSYIASQGPLLHTIEDFWRMIWEWKS CSIVMLTELEERGQEKCAQYWPSDGLVSYGDIT VELKKEEECESYTVRDLLVTNTRENKSRQIRQFH FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNH PITVHCSAGAGRTGTFCALSTVLERVKAEGILD VFQTVKSLRLQRPHMVQTLEQYEFCYKVVQEYID AFSDYANFK*AATRVRGPGGLPLIFCNILFC*Y TPNCVYIL*LF*KLVHRLLLPIRWKFYM*MC*H **SFFQCFIGELNSVMFGLIS*NPQPRNWAGLCF G*YIFP*RR*TQNPFQVARHQLRKKAQSSQSSR GKWLSPYHHAL*ISLPSLPGPLPHPHH*YHGE* *DQSGISGTTLGTIR**KL*LP

Frame 2

ARTPAAAAITVARPVAPQPLPLAMEARPPPPPR GSEPRAGRRP*GLVAARNAAAEPRRSRCPRPQR SRPTPDSVTQLKKNKGIYGIPLSGNG*CSSNN* GHMFKEHN*LFKRS**AWIPGSFLFCSAVV*YVS VPTMLPQLHLL*ELQD*LTHQRQNQLKKRPKLQ IQLLH*LLFLWHQHSAQI*LWDPPI*PLSILQT LTMGPQEQQAPIL*ALQFHQMERGFQITSSRMPE QNPGRGIPAPQQPLQKLSLLQMRHQLLR*WWPC PLC**SCLLS*FCTC*GLRNTSKLGAIPILSAY PTAALRMWSPRVCHFWPDPQAPTGNTHPCPWTSW KRKLTGEWQTTISSSGRNSTLSLHVLSRPPVRL LPRRKTRKKIDM*TSCLMTTLEST*HRLKGFQI LITSMLHSSTATKKRTNSLLHKDQKKKR*MISGG *SGNKTQPPSSWLPT*RRERSASAPSTGQTKAA GPMGIFGCL*RM*LSWWTTQYGSSASSRWAT*P TESHSASSLSSTLPAGQTLGCLLPRSACSSSSRR *RPVTLSMQGPSWSTAVQV*GVQVPLSSLMPCW T*CIQNGRWTCMAL*AGSGHSAARWCKPICSMS SYTKPFWSIISMEIQNWK*PL*KPTCRKFTTKSQ GPATMD*RRSLRS*HQSKSRMTRCGLETFQPT* RRTVFYRSFHMNSTE*SFQLSGAKRIQTM*THP LLMATGRRTPISPARALFSTQLRTSGE*SGSGNP ALS*C*QNWRREARRSVPSTGHLMDWCPMEILQ WN*RRRRNVRATPSETSWSPTPGRIRAGRSGSS TSMAGLKWASPVTERA*SASSPPCRSSSSSQGTT PSPCTAAPGQEGRGPSVP*APSWSV*KQRGFWM SSRLSRACGYRGHTWSRHWNSMSSATRWCRSIL MHSQIMPTSSKRQQGSVDQEDCL*YFVIFCFVNI PQIVYISYNCFRNWYIGFYYLLGGNFICKCVST DSPFSNVLLGN*IV*CLD*YREILSREIGLDCA LVNTSFPKEDKHKIHSR*LGTN*EKKHKVLRALE ESGCPRTTMHCKYPSPLSLVPSPIPTTDIMGSN RTRAVSLAPH*GLSGNKSFDSL

Sequence NM_080841

GTGACACAACTAAAAAAAAACAAAGGTATTTATGGAATTCCACTGAGTGGTAATGGATGATGCAGTTCAAATAACTAAGGACACATGTTCAAAGAGCATA ATTAACTTTTTAAAAGAAGCTAGACTTCTTCAGAAGCTTGCCAGTTTTTCAAGCTGATTTCTCTCACTGGCAACTCTTCAGAGTGCTGTTCCTACTCCAC CCTCCCCTGGTGATAAGCATGGATTCCTGGTTCATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTCAGTGCCAACAATGCTACCACAGTTGCACCTT CTGTAGGAATTACAAGATTAATTAACTCATCAACGGCAGAACCAGTTAAAGAAGAGGCCAAAACTTCAAATCCAACTTCTTCACTAACTTCTCTTTCTGT GGCACCAACATTCAGCCCAAATATAACTCTGGGACCCACCTATTTAACCACTGTCAATTCTTCAGACTCTGACAATGGGACCACAAGAACAGCAAGCACC AATTCTATAGGCATTACAATTTCACCAAATGGAACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAGGGGAATTCCAGCACCG CAGCAACCACTCCAGAAACTTTCCCTCCTTCAGATGAGACACCAATTATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTGATCGTGTTTATTATCAT AGTTTTGTACATGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCTTATCCAACGGCCGCACTGAGGATGTGGAGCCCCAG AGTGTGCCACTTCTGGCCAGATCCCCAAGCACCAACAGGAAATACCCACCCCTGCCCGTGGACAAGCTGGAAGAGGAAATTAACCGGAGAATGGCAGACG ACAATAAGCTCTTCAGGGAGGAATTCAACGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAATCG ATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTCATTCATCAACGGC TACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTGGGAACAAAACACAGCCACCATCG TCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTGCTGGACCTATGGGAATATTCGGGTGTCTGTAGA GGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGGCGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTC CACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGGCATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGG CCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTACAGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGT GTATGGCTTTGTGAGCCGGATCCGGGCACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTC TATGGAGATACAGAACTGGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGT TTAAGAAGTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCCATA TGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCAGAAGGACTCCTAT ATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTATCGTGATGCTAACAGAACTGGAGG AGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTACAGTGGAACTGAAGAAGGAGGAGGAATGTGAGAG CTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGATCCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCC AGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAG GAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCTGGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACA GAGGCCACACATGGTCCAGACACTGGAACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAA GCGGCAACAAGGGTCCGTGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGT TTTAGAAATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGGGGA ATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCCCTAAAGAAGATAA ACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTGGTTGTCCCCGTACCACCATGCAC TGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTAATAGGACCAGAGCGGTATCTCTGGCACCACACT AGGGACTATCAGGTAATAAAAGCTTTGACTCCCTGA

refseq_PTPRA.F1 (forward primer)
refseq_PTPRA.R1 (reverse primer)
Single exon skipping

Frame 0

VTQLKKNKGIYGIPLSGNG*CSSNN*GHMFKEH N*LFKRS*TSSEACQFFKLISLTGNSSECCSYST LPW**AWIPGSFLFCSAVV*YVSVPTMLPQLHL L*ELQD*LTHQRQNQLKKRPKLQIQLLH*LLFL WHQHSAQI*LWDPPI*PLSILQTLTMGPQEQQAP IL*ALQFHQMERGFQITSSRMPEQNPGRGIPAP QQPLQKLSLLQMRHQLLR*WWPCPLC**SCLLS *FCTC*GLRNTSKLGAIPILSAYPTAALRMWSPR VCHFWPDPQAPTGNTHPCPWTSWKRKLTGEWQT TISSSGRNSTLSLHVLSRPPVRLLPRRKTRKKI DM*TSCLMTTLEST*HRLKGFQILITSMLHSSTA TKKRTNSLLHKDQKKKR*MISGG*SGNKTQPPS SWLPT*RRERSASAPSTGQTKAAGPMGIFGCL* RM*LSWWTTQYGSSASSRWAT*PTESHSASSLSS TLPAGQTLGCLLPRSACSSSSRR*RPVTLSMQG PSWSTAVQV*GVQVPLSSLMPCWT*CIQNGRWT CMAL*AGSGHSAARWCKPICSMSSYTKPFWSIIS MEIQNWK*PL*KPTCRKFTTKSQGPATMD*RRS LRS*HQSKSRMTRCGLETFQPT*RRTVFYRSFH MNSTE*SFQLSGAKRIQTM*THPLLMATGRRTPI SPARALFSTQLRTSGE*SGSGNPALS*C*QNWR REARRSVPSTGHLMDWCPMEILQWN*RRRRNVR ATPSETSWSPTPGRIRAGRSGSSTSMAGLKWASP VTERA*SASSPPCRSSSSSQGTTPSPCTAAPGQ EGRGPSVP*APSWSV*KQRGFWMSSRLSRACGY RGHTWSRHWNSMSSATRWCRSILMHSQIMPTSSK RQQGSVDQEDCL*YFVIFCFVNIPQIVYISYNC FRNWYIGFYYLLGGNFICKCVSTDSPFSNVLLG N*IV*CLD*YREILSREIGLDCALVNTSFPKEDK HKIHSR*LGTN*EKKHKVLRALEESGCPRTTMH CKYPSPLSLVPSPIPTTDIMGSNRTRAVSLAPH *GLSGNKSFDSL

Frame 1

*HN*KKTKVFMEFH*VVMDDAVQITKDTCSKSI INFLKEARLLQKLASFSS*FLSLATLQSAVPTP PSPGDKHGFLVHSCSARQWSDMCQCQQCYHSCTF CRNYKIN*LINGRTS*RRGQNFKSNFFTNFSFC GTNIQPKYNSGTHLFNHCQFFRL*QWDHKNSKH QFYRHYNFTKWNVASR*PVHGCQNRTLGGEFQHR SNHSRNFPSFR*DTNYCGDGGPVLSASDRVYYH SFVHVKV*EIQASWEPFQFFPLIQRPH*GCGAP ECATSGQIPKHQQEIPTPARGQAGRGN*PENGRR Q*ALQGGIQRSPCMSYPGHL*GCFQGGKQGKKS ICKHLAL*PL*SPPDTG*RGSRF*LHQCFIHQR LPRKEQIHCCTRTKRRNGE*FLADDLGTKHSHHR HGYQPEGEKGVQVRPVLARPRLLDLWEYSGVCR GCDCPGGLHSTEVLHPAGGRHDQQKATAPHHSV PLYQLARLWGAFYPDRHAQVPQEGEGL*PSVCRG HRGPLQCRCRAYRYLCRH*CHAGHDAYRTEGGR VWLCEPDPGTALPDGANRYAVCLHIPSPSGALS LWRYRTGSDLSRNPPAENLQQNPRDQQQWIRGGV *EVNINQNPE*QDADWKPSSQHEEEPCFTDHSI *IQQSDHSS*AGRREYRLCERILY*WLPAEGLL YRQPGPSSPHN*GLLANDLGVEILLYRDANRTGG ERPGEVCPVLAI*WTGVLWRYYSGTEEGGGM*E LHRPRPPGHQHQGE*EPADPAVPLPWLA*SGHP Q*RKGHDQHHRRRAEAAAAVREPPHHRALQRRGR KDGDLLCPEHRPGACESRGDFGCLPDCQEPAAT EATHGPDTGTV*VLLQGGAGVY*CILRLCQLQV SGNKGPWTRRIAFNIL*YSVLLIYPKLCIYLITV LEIGT*ASITY*VEILYVNVLALIVLFPMFYWG IK*CDVWIDIVKSSAEKLGWIVLWLIHLSLKKI NTKSIPGSSAPTKKKSTKFSELSRKVVVPVPPCT VNIPPLSPWSPPPSPPLISWGVIGPERYLWHHT RDYQVIKALTP*

Frame 2

DTTKKKQRYLWNSTEW*WMMQFK*LRTHVQRA* LTF*KKLDFFRSLPVFQADFSHWQLFRVLFLLH PPLVISMDSWFILVLLGSGLICVSANNATTVAP SVGITRLINSSTAEPVKEEAKTSNPTSSLTSLSV APTFSPNITLGPTYLTTVNSSDSDNGTTRTAST NSIGITISPNGTWLPDNQFTDARTEPWEGNSST AATTPETFPPSDETPIIAVMVALSSLLVIVFIII VLYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQ SVPLLARSPSTNRKYPPLPVDKLEEEINRRMAD DNKLFREEFNALPACPIQATCEAASKEENKEKNR YVNILPYDHSRVHLTPVEGVPDSDYINASFING YQEKNKFIAAQGPKEETVNDFWRMIWEQNTATI VMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVE DVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQF HFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAG AIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDV YGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYL YGDTELEVTSLETHLQKIYNKIPGTSNNGLEEE FKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPY EFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELE ERGQEKCAQYWPSDGLVSYGDITVELKKEEECES YTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIP SDGKGMISIIAAVQKQQQQSGNHPITVHCSAGA GRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQ RPHMVQTLEQYEFCYKVVQEYIDAFSDYANFK* AATRVRGPGGLPLIFCNILFC*YTPNCVYIL*L F*KLVHRLLLPIRWKFYM*MC*H**SFFQCFIGE LNSVMFGLIS*NPQPRNWAGLCFG*YIFP*RR* TQNPFQVARHQLRKKAQSSQSSRGKWLSPYHHA L*ISLPSLPGPLPHPHH*YHGE**DQSGISGTTL GTIR**KL*LP

Sequence NM_002836

GGAGTATGAGCCACGCTCAGGGGAGCAGGTACCCCTTCTCCTAAAGATGAAGAGGAGCAAACTGGCACTAAGCAAGGCCATCGAGAGCGGGGACACTGAC CTGGTGTTCACGGTGTTGCTGCACCTGAAGAACGAGCTGAACCGAGGAGATTTTTTCATGACCCTTCGGAATCAGCCCATGGCCCTCAGTTTGTACCGAC AGTTCTGTAAGCATCAGGAGCTAGAGACGCTGAAGGACCTTTACAATCAGGATGACAATCACCAGGAATTGGGCAGCTTCCACATCCGAGCCAGCTATGC TGCAGAAGAGCGTATTGAGGGGCGAGTAGCAGCTCTGCAGACAGCCGCCGATGCCTTCTACAAGGCCAAGAATGAGTTTGCAGCCAAGGCTACAGAGGAT CAAATGCGGCTCCTACGGCTGCAGCGGCGCCTAGAAGACGAGCTGGGGGGCCAGTTCCTAGACCTGTCTCTACATGACACAGTTACCACCCTCATTCTTG GCGGTCACAACAAGCGTGCAGAGCAGCTGGCACGTGACTTCCGCATCCCTGACAAGAGGTGACACAACTAAAAAAAAACAAAGGTATTTATGGAATTCCA CTGAGTGGTAATGGATGATGCAGTTCAAATAACTAAGGACACATGTTCAAAGAGCATAATTAACTTTTTAAAAGAAGCTAATAAGCATGGATTCCTGGTT CATTCTTGTTCTGCTCGGCAGTGGTCTGATATGTGTCAGTGCCAACAATGCTACCACAGTTGCACCTTCTGTAGGAATTACAAGATTAATTAACTCATCA ACGGCAGAACCAGTTAAAGAAGAGGCCAAAACTTCAAATCCAACTTCTTCACTAACTTCTCTTTCTGTGGCACCAACATTCAGCCCAAATATAACTCTGG GACCCACCTATTTAACCACTGTCAATTCTTCAGACTCTGACAATGGGACCACAAGAACAGCAAGCACCAATTCTATAGGCATTACAATTTCACCAAATGG AACGTGGCTTCCAGATAACCAGTTCACGGATGCCAGAACAGAACCCTGGGAGGGGAATTCCAGCACCGCAGCAACCACTCCAGAAACTTTCCCTCCTTCA GGTAATTCTGACTCGAAGGACAGAAGAGATGAGACACCAATTATTGCGGTGATGGTGGCCCTGTCCTCTCTGCTAGTGATCGTGTTTATTATCATAGTTT TGTACATGTTAAGGTTTAAGAAATACAAGCAAGCTGGGAGCCATTCCAATTCTTTCCGCTTATCCAACGGCCGCACTGAGGATGTGGAGCCCCAGAGTGT GCCACTTCTGGCCAGATCCCCAAGCACCAACAGGAAATACCCACCCCTGCCCGTGGACAAGCTGGAAGAGGAAATTAACCGGAGAATGGCAGACGACAAT AAGCTCTTCAGGGAGGAATTCAACGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAATCGATATG TAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTCATTCATCAACGGCTACCA AGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTGGGAACAAAACACAGCCACCATCGTCATG GTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTGCTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATG TGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGGCGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTT TACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGGCATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATC GTGGTCCACTGCAGTGCAGGTGTAGGGCGTACAGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATG GCTTTGTGAGCCGGATCCGGGCACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGG AGATACAGAACTGGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAG AAGTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCCATATGAAT TCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCAGAAGGACTCCTATATCGC CAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTATCGTGATGCTAACAGAACTGGAGGAGAGA GGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTACAGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACA CCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGATCCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGA CGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCAGCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGG ACGGGGACCTTCTGTGCCCTGAGCACCGTCCTGGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGC CACACATGGTCCAGACACTGGAACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGC AACAAGGGTCCGTGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAG AAATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGGGGAATTAA ATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCCCTAAAGAAGATAAACACA AAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTGGTTGTCCCCGTACCACCATGCACTGTAA ATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTAATAGGACCAGAGCGGTATCTCTGGCACCACACTAGGGA CTATCAGGTAATAAAAGCTTTGACTCCCTGA

refseq_PTPRA.F1 (forward primer)
refseq_PTPRA.R1 (reverse primer)
Single exon skipping

Frame 0

GV*ATLRGAGTPSPKDEEEQTGTKQGHRERGH* PGVHGVAAPEERAEPRRFFHDPSESAHGPQFVPT VL*ASGARDAEGPLQSG*QSPGIGQLPHPSQLC CRRAY*GASSSSADSRRCLLQGQE*VCSQGYRG SNAAPTAAAAPRRRAGGPVPRPVST*HSYHPHSW RSQQACRAAGT*LPHP*QEVTQLKKNKGIYGIP LSGNG*CSSNN*GHMFKEHN*LFKRS**AWIPG SFLFCSAVV*YVSVPTMLPQLHLL*ELQD*LTHQ RQNQLKKRPKLQIQLLH*LLFLWHQHSAQI*LW DPPI*PLSILQTLTMGPQEQQAPIL*ALQFHQM ERGFQITSSRMPEQNPGRGIPAPQQPLQKLSLLQ VILTRRTEEMRHQLLR*WWPCPLC**SCLLS*F CTC*GLRNTSKLGAIPILSAYPTAALRMWSPRV CHFWPDPQAPTGNTHPCPWTSWKRKLTGEWQTTI SSSGRNSTLSLHVLSRPPVRLLPRRKTRKKIDM *TSCLMTTLEST*HRLKGFQILITSMLHSSTAT KKRTNSLLHKDQKKKR*MISGG*SGNKTQPPSSW LPT*RRERSASAPSTGQTKAAGPMGIFGCL*RM *LSWWTTQYGSSASSRWAT*PTESHSASSLSST LPAGQTLGCLLPRSACSSSSRR*RPVTLSMQGPS WSTAVQV*GVQVPLSSLMPCWT*CIQNGRWTCM AL*AGSGHSAARWCKPICSMSSYTKPFWSIISM EIQNWK*PL*KPTCRKFTTKSQGPATMD*RRSLR S*HQSKSRMTRCGLETFQPT*RRTVFYRSFHMN STE*SFQLSGAKRIQTM*THPLLMATGRRTPIS PARALFSTQLRTSGE*SGSGNPALS*C*QNWRRE ARRSVPSTGHLMDWCPMEILQWN*RRRRNVRAT PSETSWSPTPGRIRAGRSGSSTSMAGLKWASPV TERA*SASSPPCRSSSSSQGTTPSPCTAAPGQEG RGPSVP*APSWSV*KQRGFWMSSRLSRACGYRG HTWSRHWNSMSSATRWCRSILMHSQIMPTSSKR QQGSVDQEDCL*YFVIFCFVNIPQIVYISYNCFR NWYIGFYYLLGGNFICKCVSTDSPFSNVLLGN* IV*CLD*YREILSREIGLDCALVNTSFPKEDKH KIHSR*LGTN*EKKHKVLRALEESGCPRTTMHCK YPSPLSLVPSPIPTTDIMGSNRTRAVSLAPH*G LSGNKSFDSL

Frame 1

EYEPRSGEQVPLLLKMKRSKLALSKAIESGDTD LVFTVLLHLKNELNRGDFFMTLRNQPMALSLYR QFCKHQELETLKDLYNQDDNHQELGSFHIRASYA AEERIEGRVAALQTAADAFYKAKNEFAAKATED QMRLLRLQRRLEDELGGQFLDLSLHDTVTTLIL GGHNKRAEQLARDFRIPDKR*HN*KKTKVFMEFH *VVMDDAVQITKDTCSKSIINFLKEANKHGFLV HSCSARQWSDMCQCQQCYHSCTFCRNYKIN*LI NGRTS*RRGQNFKSNFFTNFSFCGTNIQPKYNSG THLFNHCQFFRL*QWDHKNSKHQFYRHYNFTKW NVASR*PVHGCQNRTLGGEFQHRSNHSRNFPSF R*F*LEGQKR*DTNYCGDGGPVLSASDRVYYHSF VHVKV*EIQASWEPFQFFPLIQRPH*GCGAPEC ATSGQIPKHQQEIPTPARGQAGRGN*PENGRRQ *ALQGGIQRSPCMSYPGHL*GCFQGGKQGKKSIC KHLAL*PL*SPPDTG*RGSRF*LHQCFIHQRLP RKEQIHCCTRTKRRNGE*FLADDLGTKHSHHRH GYQPEGEKGVQVRPVLARPRLLDLWEYSGVCRGC DCPGGLHSTEVLHPAGGRHDQQKATAPHHSVPL YQLARLWGAFYPDRHAQVPQEGEGL*PSVCRGH RGPLQCRCRAYRYLCRH*CHAGHDAYRTEGGRVW LCEPDPGTALPDGANRYAVCLHIPSPSGALSLW RYRTGSDLSRNPPAENLQQNPRDQQQWIRGGV* EVNINQNPE*QDADWKPSSQHEEEPCFTDHSI*I QQSDHSS*AGRREYRLCERILY*WLPAEGLLYR QPGPSSPHN*GLLANDLGVEILLYRDANRTGGE RPGEVCPVLAI*WTGVLWRYYSGTEEGGGM*ELH RPRPPGHQHQGE*EPADPAVPLPWLA*SGHPQ* RKGHDQHHRRRAEAAAAVREPPHHRALQRRGRK DGDLLCPEHRPGACESRGDFGCLPDCQEPAATEA THGPDTGTV*VLLQGGAGVY*CILRLCQLQVSG NKGPWTRRIAFNIL*YSVLLIYPKLCIYLITVL EIGT*ASITY*VEILYVNVLALIVLFPMFYWGIK *CDVWIDIVKSSAEKLGWIVLWLIHLSLKKINT KSIPGSSAPTKKKSTKFSELSRKVVVPVPPCTV NIPPLSPWSPPPSPPLISWGVIGPERYLWHHTRD YQVIKALTP*

Frame 2

SMSHAQGSRYPFS*R*RGANWH*ARPSRAGTLT WCSRCCCT*RTS*TEEIFS*PFGISPWPSVCTD SSVSIRS*RR*RTFTIRMTITRNWAASTSEPAM LQKSVLRGE*QLCRQPPMPSTRPRMSLQPRLQRI KCGSYGCSGA*KTSWGASS*TCLYMTQLPPSFL AVTTSVQSSWHVTSASLTRGDTTKKKQRYLWNS TEW*WMMQFK*LRTHVQRA*LTF*KKLISMDSWF ILVLLGSGLICVSANNATTVAPSVGITRLINSS TAEPVKEEAKTSNPTSSLTSLSVAPTFSPNITL GPTYLTTVNSSDSDNGTTRTASTNSIGITISPNG TWLPDNQFTDARTEPWEGNSSTAATTPETFPPS GNSDSKDRRDETPIIAVMVALSSLLVIVFIIIV LYMLRFKKYKQAGSHSNSFRLSNGRTEDVEPQSV PLLARSPSTNRKYPPLPVDKLEEEINRRMADDN KLFREEFNALPACPIQATCEAASKEENKEKNRY VNILPYDHSRVHLTPVEGVPDSDYINASFINGYQ EKNKFIAAQGPKEETVNDFWRMIWEQNTATIVM VTNLKERKECKCAQYWPDQGCWTYGNIRVSVED VTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHF TSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAI VVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVY GFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYG DTELEVTSLETHLQKIYNKIPGTSNNGLEEEFK KLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYE FNRVIIPVKRGEENTDYVNASFIDGYRQKDSYIA SQGPLLHTIEDFWRMIWEWKSCSIVMLTELEER GQEKCAQYWPSDGLVSYGDITVELKKEEECESY TVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSD GKGMISIIAAVQKQQQQSGNHPITVHCSAGAGR TGTFCALSTVLERVKAEGILDVFQTVKSLRLQR PHMVQTLEQYEFCYKVVQEYIDAFSDYANFK*AA TRVRGPGGLPLIFCNILFC*YTPNCVYIL*LF* KLVHRLLLPIRWKFYM*MC*H**SFFQCFIGEL NSVMFGLIS*NPQPRNWAGLCFG*YIFP*RR*TQ NPFQVARHQLRKKAQSSQSSRGKWLSPYHHAL* ISLPSLPGPLPHPHH*YHGE**DQSGISGTTLG TIR**KL*LP