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Sequences

Sequence NM_080423

GCTCGGGCGCCGAGTCTGCGCGCTGACGTCCGACGCTCCAGGTACTTTCCCCACGGCCGACAGGGCTTGGCGTGGGGGCGGGGCGCGGCGCGCAGCGCGC ATGCGCCGCAGCGCCAGCGCTCTCCCCGGATCGTGCGGGGCCTGAGCCTCTCCGCCGGCGCAGGCTCTGCTCGCGCCAGCTCGCTCCCGCAGCCATGCCC ACCACCATCGAGCGGGAGTTCGAAGAGTTGGATACTCAGCGTCGCTGGCAGCCGCTGTACTTGGAAATTCGAAATGAGTCCCATGACTATCCTCATAGAG TGGCCAAGTTTCCAGAAAACAGAAATCGAAACAGATACAGAGATGTAAGCCCATATGATCACAGTCGTGTTAAACTGCAAAATGCTGAGAATGATTATAT TAATGCCAGTTTAGTTGACATAGAAGAGGCACAAAGGAGTTACATCTTAACACAGGGTCCACTTCCTAACACATGCTGCCATTTCTGGCTTATGGTTTGG CAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGCATTGTGGAGAAAGAATCGGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGT TTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAAC CAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCT GGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGA TGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATA CATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGAT CATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTA AAATGCAAGATACAATGGAGGAGAACAGTGAGAGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCA TTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTT TACATCCAGGGGATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGA TGTACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTTGGCAGCATTAAATATTTTTGTTAAATA

refseq_PTPN2.F1 (forward primer)
refseq_PTPN2.R1 (reverse primer)
Single exon skipping

Frame 0

ARAPSLRADVRRSRYFPHGRQGLAWGRGAARSA HAPQRQRSPRIVRGLSLSAGAGSARASSLPQPCP PPSSGSSKSWILSVAGSRCTWKFEMSPMTILIE WPSFQKTEIETDTEM*AHMITVVLNCKMLRMII LMPV*LT*KRHKGVTS*HRVHFLTHAAISGLWFG SRRPKQLSC*TALWRKNRLNVHSTGQQMTKRCC LKKQDSV*SSCQKM*SRIIQYIYYN*KISIVVK PEQYLTFIILPGQILESLNHQLHFSISCLK*ENL AP*TLTMGLR*STVVQALGALAPSLW*TLVLF* WKKEMILT*NKCY*T*ENTEWVLFRPQIN*DSH TWL**KEQNV*REILVYRNDGKNFLRKTYLLPLI IHQTK**LKNTMGTE*V*KKKN*QVTDVQDFPL KCKIQWRRTVRGQD*QTPNIHDLRIFCSYKF*T IDVQSKT*SPLRKLK*GSLTL*IASQLFVYKVNF TSRG*RAPTSRRLCRTFNWMC*VFLMSV*NVER CTRNKLGEITLYCTAIPTVFLYFLAALNIFVK

Frame 1

LGRRVCALTSDAPGTFPTADRAWRGGGARRAAR MRRSASALPGSCGA*ASPPAQALLAPARSRSHA HHHRAGVRRVGYSASLAAAVLGNSK*VP*LSS*S GQVSRKQKSKQIQRCKPI*SQSC*TAKC*E*LY *CQFS*HRRGTKELHLNTGSTS*HMLPFLAYGL AAEDQSSCHAEPHCGERIG*MCTVLANR*PRDAV *RNRIQCEALVRRCEVVLYSTSTTIRKYQ*W*N QNNISLSLYYLARFWSP*ITSFISQFLV*SERI WLLEP*PWACGDPL*CRHWALWHLLSGRHLSCFD GKRR*Y*HKTSVTEHEKIPNGSYSDPRSTEILI HGYNRRSKMYKGRF*YTETMERTF*GRLISCL* SFTKQNND*KIQWEQNRSRRRKTDR*PMYRTFL* NARYNGGEQ*EAKIDRHLIFMT*EYSAAINFEP LMCKARPEAHSGN*SEAR*PSRLPHSCLFTK*T LHPGDEEHPPAEDFAEPLIGCVKCF**VYEM*KD VQEIN*GRLLCIVLPFLLYFYTFWQH*IFLLN

Frame 2

SGAESAR*RPTLQVLSPRPTGLGVGAGRGAQRA CAAAPALSPDRAGPEPLRRRRLCSRQLAPAAMP TTIEREFEELDTQRRWQPLYLEIRNESHDYPHR VAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYI NASLVDIEEAQRSYILTQGPLPNTCCHFWLMVW QQKTKAVVMLNRIVEKESVKCAQYWPTDDQEML FKETGFSVKLLSEDVKSYYTVHLLQLENINSGET RTISHFHYTTWPDFGVPESPASFLNFLFKVRES GSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVL MEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSY MAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFD HSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSS KMQDTMEENSERPRLTDT*YS*LENILQL*ILNH *CAKQDLKPTPETKVRLANPLDCLTVVCLQSKL YIQGMKSTHQQKTLQNL*LDVLSVFNECMKCRK MYKK*IRGDYFVLYCHSYCIFILFGSIKYFC*I

Sequence NM_080422

GCTCGGGCGCCGAGTCTGCGCGCTGACGTCCGACGCTCCAGGTACTTTCCCCACGGCCGACAGGGCTTGGCGTGGGGGCGGGGCGCGGCGCGCAGCGCGC ATGCGCCGCAGCGCCAGCGCTCTCCCCGGATCGTGCGGGGCCTGAGCCTCTCCGCCGGCGCAGGCTCTGCTCGCGCCAGCTCGCTCCCGCAGCCATGCCC ACCACCATCGAGCGGGAGTTCGAAGAGTTGGATACTCAGCGTCGCTGGCAGCCGCTGTACTTGGAAATTCGAAATGAGTCCCATGACTATCCTCATAGAG TGGCCAAGTTTCCAGAAAACAGAAATCGAAACAGATACAGAGATGTAAGCCCATATGATCACAGTCGTGTTAAACTGCAAAATGCTGAGAATGATTATAT TAATGCCAGTTTAGTTGACATAGAAGAGGCACAAAGGAGTTACATCTTAACACAGGGTCCACTTCCTAACACATGCTGCCATTTCTGGCTTATGGTTTGG CAGCAGAAGACCAAAGCAGTTGTCATGCTGAACCGCATTGTGGAGAAAGAATCGGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGT TTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAAC CAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCT GGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGA TGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATA CATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGAT CATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTA AAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGGACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAA ACAGAGGCTAAATGAGAATGAACGAAAAAGAAAAAGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAAC CATTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAAC TTTACATCCAGGGGATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAA GATGTACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTTGGCAGCATTAAATATTTTTGTTAAATA

refseq_PTPN2.F1 (forward primer)
refseq_PTPN2.R1 (reverse primer)
Single exon skipping

Frame 0

ARAPSLRADVRRSRYFPHGRQGLAWGRGAARSA HAPQRQRSPRIVRGLSLSAGAGSARASSLPQPCP PPSSGSSKSWILSVAGSRCTWKFEMSPMTILIE WPSFQKTEIETDTEM*AHMITVVLNCKMLRMII LMPV*LT*KRHKGVTS*HRVHFLTHAAISGLWFG SRRPKQLSC*TALWRKNRLNVHSTGQQMTKRCC LKKQDSV*SSCQKM*SRIIQYIYYN*KISIVVK PEQYLTFIILPGQILESLNHQLHFSISCLK*ENL AP*TLTMGLR*STVVQALGALAPSLW*TLVLF* WKKEMILT*NKCY*T*ENTEWVLFRPQIN*DSH TWL**KEQNV*REILVYRNDGKNFLRKTYLLPLI IHQTK**LKNTMGTE*V*KKKN*QVTDVQDFPL KCKIQWRRTVRVLYGNVFERTERPPQLRRCSR* NRG*MRMNEKEKGQD*QTPNIHDLRIFCSYKF*T IDVQSKT*SPLRKLK*GSLTL*IASQLFVYKVN FTSRG*RAPTSRRLCRTFNWMC*VFLMSV*NVE RCTRNKLGEITLYCTAIPTVFLYFLAALNIFVK

Frame 1

LGRRVCALTSDAPGTFPTADRAWRGGGARRAAR MRRSASALPGSCGA*ASPPAQALLAPARSRSHA HHHRAGVRRVGYSASLAAAVLGNSK*VP*LSS*S GQVSRKQKSKQIQRCKPI*SQSC*TAKC*E*LY *CQFS*HRRGTKELHLNTGSTS*HMLPFLAYGL AAEDQSSCHAEPHCGERIG*MCTVLANR*PRDAV *RNRIQCEALVRRCEVVLYSTSTTIRKYQ*W*N QNNISLSLYYLARFWSP*ITSFISQFLV*SERI WLLEP*PWACGDPL*CRHWALWHLLSGRHLSCFD GKRR*Y*HKTSVTEHEKIPNGSYSDPRSTEILI HGYNRRSKMYKGRF*YTETMERTF*GRLISCL* SFTKQNND*KIQWEQNRSRRRKTDR*PMYRTFL* NARYNGGEQ*ECSTETYSRGQKGHHSSEGAADE TEAK*E*TKKKKAKIDRHLIFMT*EYSAAINFE PLMCKARPEAHSGN*SEAR*PSRLPHSCLFTK*T LHPGDEEHPPAEDFAEPLIGCVKCF**VYEM*K DVQEIN*GRLLCIVLPFLLYFYTFWQH*IFLLN

Frame 2

SGAESAR*RPTLQVLSPRPTGLGVGAGRGAQRA CAAAPALSPDRAGPEPLRRRRLCSRQLAPAAMP TTIEREFEELDTQRRWQPLYLEIRNESHDYPHR VAKFPENRNRNRYRDVSPYDHSRVKLQNAENDYI NASLVDIEEAQRSYILTQGPLPNTCCHFWLMVW QQKTKAVVMLNRIVEKESVKCAQYWPTDDQEML FKETGFSVKLLSEDVKSYYTVHLLQLENINSGET RTISHFHYTTWPDFGVPESPASFLNFLFKVRES GSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVL MEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSY MAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFD HSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSS KMQDTMEENSESALRKRIREDRKATTAQKVQQMK QRLNENERKRKRPRLTDT*YS*LENILQL*ILN H*CAKQDLKPTPETKVRLANPLDCLTVVCLQSK LYIQGMKSTHQQKTLQNL*LDVLSVFNECMKCRK MYKK*IRGDYFVLYCHSYCIFILFGSIKYFC*I