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Sequences

Sequence NM_001005242

GTGGCGGCTTCGCCCGCGAGTCCAGAGGCAGGCGAGCAGCTCGGTCGCCCCCACCGGCCCCATGGCAGCCCCCGGCGCCCCAGCTGAGTACGGCTACATC CGGACCGTCCTGGGCCAGCAGATCCTGGGACAACTGGACAGCTCCAGCCTGGCGCTGCCCTCCGAGGCCAAGCTGAAGCTGGCGGGGAGCAGCGGCCGCG GCGGCCAGACAGTCAAGAGCCTGCGGATCCAGGAGCAGGTGCAGCAGACCCTCGCCCGGAAGGGCCGCAGCTCCGTGGGCAACGGAAATCTTCACCGAAC CAGCAGTGTTCCTGAGTATGTCTACAACCTACACTTGGTTGAAAATGATTTTGTTGGAGGCCGTTCCCCTGTTCCTAAAACCTATGACATGCTAAAGGCT GGCACAACTGCCACTTATGAAGGTCGCTGGGGAAGAGGAACAGCACAGTACAGCTCCCAGAAGTCCGTGGAAGAAAGGTCCTTGAGGCATCCTCTGAGGA GACTGGAGATTTCTCCTGACAGCAGCCCGGAGAGGGCTCACTACACGCACAGCGATTACCAGTACAGCCAGAGAAGCCAGGCTGGGCACACCCTGCACCA CCAAGAAAGCAGGCGGGCCGCCCTCCTAGTGCCACCGAGATATGCTCGTTCCGAGATCGTGGGGGTCAGCCGTGCTGGCACCACAAGCAGGCAGCGCCAC TTTGACACATACCACAGACAGTACCAGCATGGCTCTGTTAGCGACACCGTTTTTGACAGCATCCCTGCCAACCCGGCCCTGCTCACGTACCCCAGGCCAG GGACCAGCCGCAGCATGGGCAACCTCTTGGAGAAGGAGAACTACCTGACGGCAGGGCTCACTGTCGGGCAGGTCAGGCCGCTGGTGCCCCTGCAGCCCGT CACTCAGAACAGGGCTTCCAGGTCCTCCTGGCATCAGAGCTCCTTCCACAGCACCCGCACGCTGAGGGAAGCTGGGCCCAGTGTCGCCGTGGATTCCAGC GGGAGGAGAGCGCACTTGACTGTCGGCCAGGCGGCCGCAGGGGGAAGTGGGAATCTGCTCACTGAGAGAAGCACTTTCACTGACTCCCAGCTGGGGAATG CAGACATGGAGATGACTCTGGAGCGAGCAGTGAGTATGCTCGAGGCAGACCACATGCTGCCATCCAGGATTTCTGCTGCAGCTACTTTCATACAGCACGA GTGCTTCCAGAAATCTGAAGCTCGGAAGAGGGTTAACCAGCTTCGTGGCATCCTCAAGCTTCTGCAGCTCCTAAAAGTTCAGAATGAAGACGTTCAGCGA GCTGTGTGTGGGGCCTTGAGAAACTTAGTATTTGAAGACAATGACAACAAATTGGAGGTGGCTGAACTAAATGGGGTACCTCGGCTGCTCCAGGTGCTGA AGCAAACCAGAGACTTGGAGACTAAAAAACAAATAACAGGTTTGCTGTGGAATTTGTCATCTAATGACAAACTCAAGAATCTCATGATAACAGAAGCATT GCTTACGCTGACGGAGAATATCATCATCCCCTTTTCTGGGTGGCCTGAAGGAGACTACCCAAAAGCAAATGGTTTGCTCGATTTTGACATATTCTACAAC GTCACTGGATGCCTAAGAAACATGAGTTCTGCTGGCGCTGATGGGAGAAAAGCGATGAGAAGATGTGACGGACTCATTGACTCACTGGTCCATTATGTCA GAGGAACCATTGCAGATTACCAGCCAGATGACAAGGCCACGGAGAATTGTGTGTGCATTCTTCATAACCTCTCCTACCAGCTGGAGGCAGAGCTCCCAGA GAAATATTCCCAGAATATCTATATTCAAAACCGGAATATCCAGACTGACAACAACAAAAGTATTGGATGTTTTGGCAGTCGAAGCAGGAAAGTAAAAGAG CAATACCAGGACGTGCCGATGCCGGAGGAAAAGAGCAACCCCAAGGGCGTGGAGTGGCTGTGGCATTCCATTGTTATAAGGATGTATCTGTCCTTGATCG CCAAAAGTGTCCGCAACTACACACAAGAAGCATCCTTAGGAGCTCTGCAGAACCTCACGGCCGGAAGTGGACCAATGCCGACATCAGTGGCTCAGACAGT TGTCCAGAAGGAAAGTGGCCTGCAGCACACCCGAAAGATGCTGCATGTTGGTGACCCAAGTGTGAAAAAGACAGCCATCTCGCTGCTGAGGAATCTGTCC CGGAATCTTTCTCTGCAGAATGAAATTGCCAAAGAAACTCTCCCTGATTTGGTTTCCATCATTCCTGACACAGTCCCGAGTACTGACCTTCTCATTGAAA CTACAGCCTCTGCCTGTTACACATTGAACAACATAATCCAAAACAGTTACCAGAATGCACGCGACCTTCTAAACACCGGGGGCATCCAGAAAATTATGGC CATTAGTGCAGGCGATGCCTATGCCTCCAACAAAGCAAGTAAAGCTGCTTCCGTCCTTCTGTATTCTCTGTGGGCACACACGGAACTGCATCATGCCTAC AAGAAGGCTCAGTTTAAGAAGACAGATTTTGTCAACAGCCGGACTGCCAAAGCCTACCACTCCCTTAAAGACTGAGGAAAATGACAAAGTATTCTCGGCT GCAAAAATCCCCAAAGGAAAACACCTATTTTTCTACTACCCAGCCCAAGAAACCTCAAAAGCATGCCTTGTTTCTATCCTTCTCTATTTCCGTGGTCCCC TGAATCCAGAAAACAAATAGAACATAATTTTATGAGTCTTCCAGAAGACCTTTGCAAGTTTGCCACCAGTAGATACCGGCCACAGGCTCGACAAATAGTG GTCTTTGTTATTAGGGCTTATGGTACATGGCTTCCTGGAATCAAAATGTGAATTCATGTGGAAGGGACATTAATCCAATAAATAAGGAAAGAAGCTGTTG CATTACTGGGATTTTAAAAGTTTGATTTACATTTATATTCCTTTTCTGGTTCCCATGTTTTGTCACTCATGTGCACATTGCTTCGCCATTGGGCCTCCAG TGTATTGTTCTGCAGTGTTGAAACAGAATGGAAATGACAAGAAATATCTGCAGTTATCCAGGAGAAAGTATAATGGCAAAATTATTGGTTTCTTTCTTTA CTTTGTGCTTGTTTTTATCCCCTTGGGTTGTTTTTCTCTGATTTTTAAATAAACTTAAGAAATTTAGATTACAGAGTATGCATGACTGTAAGAAAAAGAA ATTGAGAGGAAGTGATCATAGCAAATTAAAGAAGTCTTTTCCTCCCAGAACTTAAAGTAAAATAAAAAATAAATAAATAAATAAAATCTTTTCCACAGAG AAAGGCAACTGTGATGATAAAATTTAACGTTCCCCCAAACACTGAGTCAATGAGATTTTTCTCAGGAGATACTTTACCTATAACAACGCCGTTAAATCCA AATCTCTTCTAAACGATGGCATTCTATGTAATGCCTTTCCTGGACTTTTTTGGCCACTGCCCTGGACTAGTGAAAGAATGGACTCTATCTTTATCTGCAA GAGGAACTAAGGCCTTCTCTCAGACTGCCTGGCCAGCCTGGGGCACTGAAAATACGGCTCATGTTAATGAGTTACATTATCAGCCAGCCCAGCCTTGCCC ACCATTTAAGAAATATCACAGAGCCACTAGATCTCATATGATCTTCTTCAAGCCATTATTTTAACTCAAGAAAACTCTAGAGAAGAAAAGTGAAGAAGTC ATGTTGAAGAAGATGTAAGAATGTGTCAAGACCATCCAGAAATGATATGAGAAATACTGATATTTTAAATGGTTGACATCATCCAGCGAAATGAATCTAC ATTAAATGTTGTTTTAACTGCGCTATGATTAAAACCATTCATATAGAGTTAGTCTTTACAACTACTATTCTGTTATTTTTTTTTTTAATCTGACAACATT TGTCCTAAGTAAGATAAGCAAAAAAATTCTTCAACTCCTTTTGGCAAGAAAACTGTAACAGAAAATAAATTTTGAATGTGTACTTAAGTCTTTATTATAT TTGAAGCAATTTTTTTTCAATTTTAAAAGCTGAATGAAGACAACTTAGGTTGCTAACCTAGTTCAAAATGAAATTATTTAGATACCAATTTTTAAAATAC TGGAGAGAATTTATATGTCTTTTTCCAGAGTTCTGATGATAAGCATTTGGAGTGCATTTATTCCTCCAGATAATAAATGTGTGTTCAGAACTTTTTGTGT TTTTTAAGGCATTAATAAAGCCTTCGATAATATTAAATACAAAATGA

refseq_PKP2.F2 (forward primer)
refseq_PKP2.R2 (reverse primer)
Single exon skipping

Frame 0

VAASPASPEAGEQLGRPHRPHGSPRRPS*VRLH PDRPGPADPGTTGQLQPGAALRGQAEAGGEQRPR RPDSQEPADPGAGAADPRPEGPQLRGQRKSSPN QQCS*VCLQPTLG*K*FCWRPFPCS*NL*HAKG WHNCHL*RSLGKRNSTVQLPEVRGRKVLEASSEE TGDFS*QQPGEGSLHAQRLPVQPEKPGWAHPAP PRKQAGRPPSATEICSFRDRGGQPCWHHKQAAP L*HIPQTVPAWLC*RHRF*QHPCQPGPAHVPQAR DQPQHGQPLGEGELPDGRAHCRAGQAAGAPAAR HSEQGFQVLLASELLPQHPHAEGSWAQCRRGFQ REESALDCRPGGRRGKWESAH*EKHFH*LPAGEC RHGDDSGASSEYARGRPHAAIQDFCCSYFHTAR VLPEI*SSEEG*PASWHPQASAAPKSSE*RRSA SCVWGLEKLSI*RQ*QQIGGG*TKWGTSAAPGAE ANQRLGD*KTNNRFAVEFVI**QTQESHDNRSI AYADGEYHHPLFWVA*RRLPKSKWFARF*HILQ RHWMPKKHEFCWR*WEKSDEKM*RTH*LTGPLCQ RNHCRLPAR*QGHGELCVHSS*PLLPAGGRAPR EIFPEYLYSKPEYPD*QQQKYWMFWQSKQESKR AIPGRADAGGKEQPQGRGVAVAFHCYKDVSVLDR QKCPQLHTRSILRSSAEPHGRKWTNADISGSDS CPEGKWPAAHPKDAACW*PKCEKDSHLAAEESV PESFSAE*NCQRNSP*FGFHHS*HSPEY*PSH*N YSLCLLHIEQHNPKQLPECTRPSKHRGHPENYG H*CRRCLCLQQSK*SCFRPSVFSVGTHGTASCL QEGSV*EDRFCQQPDCQSLPLP*RLRKMTKYSRL QKSPKENTYFSTTQPKKPQKHALFLSFSISVVP *IQKTNRT*FYESSRRPLQVCHQ*IPATGSTNS GLCY*GLWYMASWNQNVNSCGRDINPINKERSCC ITGILKV*FTFIFLFWFPCFVTHVHIASPLGLQ CIVLQC*NRMEMTRNICSYPGESIMAKLLVSFF TLCLFLSPWVVFL*FLNKLKKFRLQSMHDCKKKK LRGSDHSKLKKSFPPRT*SKIKNK*INKIFSTE KGNCDDKI*RSPKH*VNEIFLRRYFTYNNAVKS KSLLNDGILCNAFPGLFWPLPWTSERMDSIFICK RN*GLLSDCLASLGH*KYGSC**VTLSASPALP TI*EISQSH*ISYDLLQAIILTQENSREEK*RS HVEEDVRMCQDHPEMI*EILIF*MVDIIQRNEST LNVVLTAL*LKPFI*S*SLQLLFCYFFF*SDNI CPK*DKQKNSSTPFGKKTVTENKF*MCT*VFII FEAIFFQF*KLNEDNLGC*PSSK*NYLDTNF*NT GENLYVFFQSSDDKHLECIYSSR**MCVQNFLC FLRH**SLR*Y*IQN

Frame 1

WRLRPRVQRQASSSVAPTGPMAAPGAPAEYGYI RTVLGQQILGQLDSSSLALPSEAKLKLAGSSGR GGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRT SSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKA GTTATYEGRWGRGTAQYSSQKSVEERSLRHPLR RLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH QESRRAALLVPPRYARSEIVGVSRAGTTSRQRH FDTYHRQYQHGSVSDTVFDSIPANPALLTYPRP GTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPV TQNRASRSSWHQSSFHSTRTLREAGPSVAVDSS GRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGN ADMEMTLERAVSMLEADHMLPSRISAAATFIQHE CFQKSEARKRVNQLRGILKLLQLLKVQNEDVQR AVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL KQTRDLETKKQITGLLWNLSSNDKLKNLMITEAL LTLTENIIIPFSGWPEGDYPKANGLLDFDIFYN VTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYV RGTIADYQPDDKATENCVCILHNLSYQLEAELPE KYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKE QYQDVPMPEEKSNPKGVEWLWHSIVIRMYLSLI AKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTV VQKESGLQHTRKMLHVGDPSVKKTAISLLRNLS RNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIE TTASACYTLNNIIQNSYQNARDLLNTGGIQKIMA ISAGDAYASNKASKAASVLLYSLWAHTELHHAY KKAQFKKTDFVNSRTAKAYHSLKD*GK*QSILG CKNPQRKTPIFLLPSPRNLKSMPCFYPSLFPWSP ESRKQIEHNFMSLPEDLCKFATSRYRPQARQIV VFVIRAYGTWLPGIKM*IHVEGTLIQ*IRKEAV ALLGF*KFDLHLYSFSGSHVLSLMCTLLRHWASS VLFCSVETEWK*QEISAVIQEKV*WQNYWFLSL LCACFYPLGLFFSDF*INLRNLDYRVCMTVRKR N*EEVIIAN*RSLFLPELKVK*KINK*IKSFPQR KATVMIKFNVPPNTESMRFFSGDTLPITTPLNP NLF*TMAFYVMPFLDFFGHCPGLVKEWTLSLSA RGTKAFSQTAWPAWGTENTAHVNELHYQPAQPCP PFKKYHRATRSHMIFFKPLF*LKKTLEKKSEEV MLKKM*ECVKTIQK*YEKY*YFKWLTSSSEMNL H*MLF*LRYD*NHSYRVSLYNYYSVIFFFNLTTF VLSKISKKILQLLLARKL*QKINFECVLKSLLY LKQFFFNFKS*MKTT*VANLVQNEII*IPIFKI LERIYMSFSRVLMISIWSAFIPPDNKCVFRTFCV F*GINKAFDNIKYKM

Frame 2

GGFARESRGRRAARSPPPAPWQPPAPQLSTATS GPSWASRSWDNWTAPAWRCPPRPS*SWRGAAAA AARQSRACGSRSRCSRPSPGRAAAPWATEIFTE PAVFLSMSTTYTWLKMILLEAVPLFLKPMTC*RL AQLPLMKVAGEEEQHSTAPRSPWKKGP*GIL*G DWRFLLTAARRGLTTRTAITSTAREARLGTPCT TKKAGGPPS*CHRDMLVPRSWGSAVLAPQAGSAT LTHTTDSTSMALLATPFLTASLPTRPCSRTPGQ GPAAAWATSWRRRTT*RQGSLSGRSGRWCPCSP SLRTGLPGPPGIRAPSTAPAR*GKLGPVSPWIPA GGERT*LSARRPQGEVGICSLREALSLTPSWGM QTWR*LWSEQ*VCSRQTTCCHPGFLLQLLSYST SASRNLKLGRGLTSFVASSSFCSS*KFRMKTFSE LCVGP*ET*YLKTMTTNWRWLN*MGYLGCSRC* SKPETWRLKNK*QVCCGICHLMTNSRIS**QKH CLR*RRISSSPFLGGLKETTQKQMVCSILTYSTT SLDA*ET*VLLALMGEKR*EDVTDSLTHWSIMS EEPLQITSQMTRPRRIVCAFFITSPTSWRQSSQ RNIPRISIFKTGISRLTTTKVLDVLAVEAGK*KS NTRTCRCRRKRATPRAWSGCGIPLL*GCICP*S PKVSATTHKKHP*ELCRTSRPEVDQCRHQWLRQ LSRRKVACSTPERCCMLVTQV*KRQPSRC*GICP GIFLCRMKLPKKLSLIWFPSFLTQSRVLTFSLK LQPLPVTH*TT*SKTVTRMHATF*TPGASRKLW PLVQAMPMPPTKQVKLLPSFCILCGHTRNCIMPT RRLSLRRQILSTAGLPKPTTPLKTEENDKVFSA AKIPKGKHLFFYYPAQETSKACLVSILLYFRGP LNPENK*NIIL*VFQKTFASLPPVDTGHRLDK*W SLLLGLMVHGFLESKCEFMWKGH*SNK*GKKLL HYWDFKSLIYIYIPFLVPMFCHSCAHCFAIGPP VYCSAVLKQNGNDKKYLQLSRRKYNGKIIGFFLY FVLVFIPLGCFSLIFK*T*EI*ITEYA*L*EKE IERK*S*QIKEVFSSQNLK*NKK*INK*NLFHR ERQL***NLTFPQTLSQ*DFSQEILYL*QRR*IQ ISSKRWHSM*CLSWTFLATALD**KNGLYLYLQ EELRPSLRLPGQPGALKIRLMLMSYIISQPSLA HHLRNITEPLDLI*SSSSHYFNSRKL*RRKVKKS C*RRCKNVSRPSRNDMRNTDILNG*HHPAK*IY IKCCFNCAMIKTIHIELVFTTTILLFFFLI*QH LS*VR*AKKFFNSFWQENCNRK*ILNVYLSLYYI *SNFFSILKAE*RQLRLLT*FKMKLFRYQFLKY WREFICLFPEF***AFGVHLFLQIINVCSELFV FFKALIKPSIILNTK*

Sequence NM_004572

GTGGCGGCTTCGCCCGCGAGTCCAGAGGCAGGCGAGCAGCTCGGTCGCCCCCACCGGCCCCATGGCAGCCCCCGGCGCCCCAGCTGAGTACGGCTACATC CGGACCGTCCTGGGCCAGCAGATCCTGGGACAACTGGACAGCTCCAGCCTGGCGCTGCCCTCCGAGGCCAAGCTGAAGCTGGCGGGGAGCAGCGGCCGCG GCGGCCAGACAGTCAAGAGCCTGCGGATCCAGGAGCAGGTGCAGCAGACCCTCGCCCGGAAGGGCCGCAGCTCCGTGGGCAACGGAAATCTTCACCGAAC CAGCAGTGTTCCTGAGTATGTCTACAACCTACACTTGGTTGAAAATGATTTTGTTGGAGGCCGTTCCCCTGTTCCTAAAACCTATGACATGCTAAAGGCT GGCACAACTGCCACTTATGAAGGTCGCTGGGGAAGAGGAACAGCACAGTACAGCTCCCAGAAGTCCGTGGAAGAAAGGTCCTTGAGGCATCCTCTGAGGA GACTGGAGATTTCTCCTGACAGCAGCCCGGAGAGGGCTCACTACACGCACAGCGATTACCAGTACAGCCAGAGAAGCCAGGCTGGGCACACCCTGCACCA CCAAGAAAGCAGGCGGGCCGCCCTCCTAGTGCCACCGAGATATGCTCGTTCCGAGATCGTGGGGGTCAGCCGTGCTGGCACCACAAGCAGGCAGCGCCAC TTTGACACATACCACAGACAGTACCAGCATGGCTCTGTTAGCGACACCGTTTTTGACAGCATCCCTGCCAACCCGGCCCTGCTCACGTACCCCAGGCCAG GGACCAGCCGCAGCATGGGCAACCTCTTGGAGAAGGAGAACTACCTGACGGCAGGGCTCACTGTCGGGCAGGTCAGGCCGCTGGTGCCCCTGCAGCCCGT CACTCAGAACAGGGCTTCCAGGTCCTCCTGGCATCAGAGCTCCTTCCACAGCACCCGCACGCTGAGGGAAGCTGGGCCCAGTGTCGCCGTGGATTCCAGC GGGAGGAGAGCGCACTTGACTGTCGGCCAGGCGGCCGCAGGGGGAAGTGGGAATCTGCTCACTGAGAGAAGCACTTTCACTGACTCCCAGCTGGGGAATG CAGACATGGAGATGACTCTGGAGCGAGCAGTGAGTATGCTCGAGGCAGACCACATGCTGCCATCCAGGATTTCTGCTGCAGCTACTTTCATACAGCACGA GTGCTTCCAGAAATCTGAAGCTCGGAAGAGGGTTAACCAGCTTCGTGGCATCCTCAAGCTTCTGCAGCTCCTAAAAGTTCAGAATGAAGACGTTCAGCGA GCTGTGTGTGGGGCCTTGAGAAACTTAGTATTTGAAGACAATGACAACAAATTGGAGGTGGCTGAACTAAATGGGGTACCTCGGCTGCTCCAGGTGCTGA AGCAAACCAGAGACTTGGAGACTAAAAAACAAATAACAGACCATACAGTCAATTTAAGAAGTAGGAATGGCTGGCCGGGCGCGGTGGCTCACGCCTGTAA TCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTTTGCTGTGGAATTTGTCATCTAATGAC AAACTCAAGAATCTCATGATAACAGAAGCATTGCTTACGCTGACGGAGAATATCATCATCCCCTTTTCTGGGTGGCCTGAAGGAGACTACCCAAAAGCAA ATGGTTTGCTCGATTTTGACATATTCTACAACGTCACTGGATGCCTAAGAAACATGAGTTCTGCTGGCGCTGATGGGAGAAAAGCGATGAGAAGATGTGA CGGACTCATTGACTCACTGGTCCATTATGTCAGAGGAACCATTGCAGATTACCAGCCAGATGACAAGGCCACGGAGAATTGTGTGTGCATTCTTCATAAC CTCTCCTACCAGCTGGAGGCAGAGCTCCCAGAGAAATATTCCCAGAATATCTATATTCAAAACCGGAATATCCAGACTGACAACAACAAAAGTATTGGAT GTTTTGGCAGTCGAAGCAGGAAAGTAAAAGAGCAATACCAGGACGTGCCGATGCCGGAGGAAAAGAGCAACCCCAAGGGCGTGGAGTGGCTGTGGCATTC CATTGTTATAAGGATGTATCTGTCCTTGATCGCCAAAAGTGTCCGCAACTACACACAAGAAGCATCCTTAGGAGCTCTGCAGAACCTCACGGCCGGAAGT GGACCAATGCCGACATCAGTGGCTCAGACAGTTGTCCAGAAGGAAAGTGGCCTGCAGCACACCCGAAAGATGCTGCATGTTGGTGACCCAAGTGTGAAAA AGACAGCCATCTCGCTGCTGAGGAATCTGTCCCGGAATCTTTCTCTGCAGAATGAAATTGCCAAAGAAACTCTCCCTGATTTGGTTTCCATCATTCCTGA CACAGTCCCGAGTACTGACCTTCTCATTGAAACTACAGCCTCTGCCTGTTACACATTGAACAACATAATCCAAAACAGTTACCAGAATGCACGCGACCTT CTAAACACCGGGGGCATCCAGAAAATTATGGCCATTAGTGCAGGCGATGCCTATGCCTCCAACAAAGCAAGTAAAGCTGCTTCCGTCCTTCTGTATTCTC TGTGGGCACACACGGAACTGCATCATGCCTACAAGAAGGCTCAGTTTAAGAAGACAGATTTTGTCAACAGCCGGACTGCCAAAGCCTACCACTCCCTTAA AGACTGAGGAAAATGACAAAGTATTCTCGGCTGCAAAAATCCCCAAAGGAAAACACCTATTTTTCTACTACCCAGCCCAAGAAACCTCAAAAGCATGCCT TGTTTCTATCCTTCTCTATTTCCGTGGTCCCCTGAATCCAGAAAACAAATAGAACATAATTTTATGAGTCTTCCAGAAGACCTTTGCAAGTTTGCCACCA GTAGATACCGGCCACAGGCTCGACAAATAGTGGTCTTTGTTATTAGGGCTTATGGTACATGGCTTCCTGGAATCAAAATGTGAATTCATGTGGAAGGGAC ATTAATCCAATAAATAAGGAAAGAAGCTGTTGCATTACTGGGATTTTAAAAGTTTGATTTACATTTATATTCCTTTTCTGGTTCCCATGTTTTGTCACTC ATGTGCACATTGCTTCGCCATTGGGCCTCCAGTGTATTGTTCTGCAGTGTTGAAACAGAATGGAAATGACAAGAAATATCTGCAGTTATCCAGGAGAAAG TATAATGGCAAAATTATTGGTTTCTTTCTTTACTTTGTGCTTGTTTTTATCCCCTTGGGTTGTTTTTCTCTGATTTTTAAATAAACTTAAGAAATTTAGA TTACAGAGTATGCATGACTGTAAGAAAAAGAAATTGAGAGGAAGTGATCATAGCAAATTAAAGAAGTCTTTTCCTCCCAGAACTTAAAGTAAAATAAAAA ATAAATAAATAAATAAAATCTTTTCCACAGAGAAAGGCAACTGTGATGATAAAATTTAACGTTCCCCCAAACACTGAGTCAATGAGATTTTTCTCAGGAG ATACTTTACCTATAACAACGCCGTTAAATCCAAATCTCTTCTAAACGATGGCATTCTATGTAATGCCTTTCCTGGACTTTTTTGGCCACTGCCCTGGACT AGTGAAAGAATGGACTCTATCTTTATCTGCAAGAGGAACTAAGGCCTTCTCTCAGACTGCCTGGCCAGCCTGGGGCACTGAAAATACGGCTCATGTTAAT GAGTTACATTATCAGCCAGCCCAGCCTTGCCCACCATTTAAGAAATATCACAGAGCCACTAGATCTCATATGATCTTCTTCAAGCCATTATTTTAACTCA AGAAAACTCTAGAGAAGAAAAGTGAAGAAGTCATGTTGAAGAAGATGTAAGAATGTGTCAAGACCATCCAGAAATGATATGAGAAATACTGATATTTTAA ATGGTTGACATCATCCAGCGAAATGAATCTACATTAAATGTTGTTTTAACTGCGCTATGATTAAAACCATTCATATAGAGTTAGTCTTTACAACTACTAT TCTGTTATTTTTTTTTTTAATCTGACAACATTTGTCCTAAGTAAGATAAGCAAAAAAATTCTTCAACTCCTTTTGGCAAGAAAACTGTAACAGAAAATAA ATTTTGAATGTGTACTTAAGTCTTTATTATATTTGAAGCAATTTTTTTTCAATTTTAAAAGCTGAATGAAGACAACTTAGGTTGCTAACCTAGTTCAAAA TGAAATTATTTAGATACCAATTTTTAAAATACTGGAGAGAATTTATATGTCTTTTTCCAGAGTTCTGATGATAAGCATTTGGAGTGCATTTATTCCTCCA GATAATAAATGTGTGTTCAGAACTTTTTGTGTTTTTTAAGGCATTAATAAAGCCTTCGATAATATTAAATACAAAATGA

refseq_PKP2.F2 (forward primer)
refseq_PKP2.R2 (reverse primer)
Single exon skipping

Frame 0

VAASPASPEAGEQLGRPHRPHGSPRRPS*VRLH PDRPGPADPGTTGQLQPGAALRGQAEAGGEQRPR RPDSQEPADPGAGAADPRPEGPQLRGQRKSSPN QQCS*VCLQPTLG*K*FCWRPFPCS*NL*HAKG WHNCHL*RSLGKRNSTVQLPEVRGRKVLEASSEE TGDFS*QQPGEGSLHAQRLPVQPEKPGWAHPAP PRKQAGRPPSATEICSFRDRGGQPCWHHKQAAP L*HIPQTVPAWLC*RHRF*QHPCQPGPAHVPQAR DQPQHGQPLGEGELPDGRAHCRAGQAAGAPAAR HSEQGFQVLLASELLPQHPHAEGSWAQCRRGFQ REESALDCRPGGRRGKWESAH*EKHFH*LPAGEC RHGDDSGASSEYARGRPHAAIQDFCCSYFHTAR VLPEI*SSEEG*PASWHPQASAAPKSSE*RRSA SCVWGLEKLSI*RQ*QQIGGG*TKWGTSAAPGAE ANQRLGD*KTNNRPYSQFKK*EWLAGRGGSRL* SQHFGRPRRADHEVRSSRPA*PTWFAVEFVI** QTQESHDNRSIAYADGEYHHPLFWVA*RRLPKSK WFARF*HILQRHWMPKKHEFCWR*WEKSDEKM* RTH*LTGPLCQRNHCRLPAR*QGHGELCVHSS* PLLPAGGRAPREIFPEYLYSKPEYPD*QQQKYWM FWQSKQESKRAIPGRADAGGKEQPQGRGVAVAF HCYKDVSVLDRQKCPQLHTRSILRSSAEPHGRK WTNADISGSDSCPEGKWPAAHPKDAACW*PKCEK DSHLAAEESVPESFSAE*NCQRNSP*FGFHHS* HSPEY*PSH*NYSLCLLHIEQHNPKQLPECTRP SKHRGHPENYGH*CRRCLCLQQSK*SCFRPSVFS VGTHGTASCLQEGSV*EDRFCQQPDCQSLPLP* RLRKMTKYSRLQKSPKENTYFSTTQPKKPQKHA LFLSFSISVVP*IQKTNRT*FYESSRRPLQVCHQ *IPATGSTNSGLCY*GLWYMASWNQNVNSCGRD INPINKERSCCITGILKV*FTFIFLFWFPCFVT HVHIASPLGLQCIVLQC*NRMEMTRNICSYPGES IMAKLLVSFFTLCLFLSPWVVFL*FLNKLKKFR LQSMHDCKKKKLRGSDHSKLKKSFPPRT*SKIK NK*INKIFSTEKGNCDDKI*RSPKH*VNEIFLRR YFTYNNAVKSKSLLNDGILCNAFPGLFWPLPWT SERMDSIFICKRN*GLLSDCLASLGH*KYGSC* *VTLSASPALPTI*EISQSH*ISYDLLQAIILTQ ENSREEK*RSHVEEDVRMCQDHPEMI*EILIF* MVDIIQRNESTLNVVLTAL*LKPFI*S*SLQLL FCYFFF*SDNICPK*DKQKNSSTPFGKKTVTENK F*MCT*VFIIFEAIFFQF*KLNEDNLGC*PSSK *NYLDTNF*NTGENLYVFFQSSDDKHLECIYSS R**MCVQNFLCFLRH**SLR*Y*IQN

Frame 1

WRLRPRVQRQASSSVAPTGPMAAPGAPAEYGYI RTVLGQQILGQLDSSSLALPSEAKLKLAGSSGR GGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRT SSVPEYVYNLHLVENDFVGGRSPVPKTYDMLKA GTTATYEGRWGRGTAQYSSQKSVEERSLRHPLR RLEISPDSSPERAHYTHSDYQYSQRSQAGHTLHH QESRRAALLVPPRYARSEIVGVSRAGTTSRQRH FDTYHRQYQHGSVSDTVFDSIPANPALLTYPRP GTSRSMGNLLEKENYLTAGLTVGQVRPLVPLQPV TQNRASRSSWHQSSFHSTRTLREAGPSVAVDSS GRRAHLTVGQAAAGGSGNLLTERSTFTDSQLGN ADMEMTLERAVSMLEADHMLPSRISAAATFIQHE CFQKSEARKRVNQLRGILKLLQLLKVQNEDVQR AVCGALRNLVFEDNDNKLEVAELNGVPRLLQVL KQTRDLETKKQITDHTVNLRSRNGWPGAVAHACN PSTLGGQGGRITRSGVRDQPDQHGLLWNLSSND KLKNLMITEALLTLTENIIIPFSGWPEGDYPKA NGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCD GLIDSLVHYVRGTIADYQPDDKATENCVCILHN LSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIG CFGSRSRKVKEQYQDVPMPEEKSNPKGVEWLWHS IVIRMYLSLIAKSVRNYTQEASLGALQNLTAGS GPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVK KTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPD TVPSTDLLIETTASACYTLNNIIQNSYQNARDL LNTGGIQKIMAISAGDAYASNKASKAASVLLYS LWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLK D*GK*QSILGCKNPQRKTPIFLLPSPRNLKSMP CFYPSLFPWSPESRKQIEHNFMSLPEDLCKFAT SRYRPQARQIVVFVIRAYGTWLPGIKM*IHVEGT LIQ*IRKEAVALLGF*KFDLHLYSFSGSHVLSL MCTLLRHWASSVLFCSVETEWK*QEISAVIQEK V*WQNYWFLSLLCACFYPLGLFFSDF*INLRNLD YRVCMTVRKRN*EEVIIAN*RSLFLPELKVK*K INK*IKSFPQRKATVMIKFNVPPNTESMRFFSG DTLPITTPLNPNLF*TMAFYVMPFLDFFGHCPGL VKEWTLSLSARGTKAFSQTAWPAWGTENTAHVN ELHYQPAQPCPPFKKYHRATRSHMIFFKPLF*L KKTLEKKSEEVMLKKM*ECVKTIQK*YEKY*YFK WLTSSSEMNLH*MLF*LRYD*NHSYRVSLYNYY SVIFFFNLTTFVLSKISKKILQLLLARKL*QKI NFECVLKSLLYLKQFFFNFKS*MKTT*VANLVQN EII*IPIFKILERIYMSFSRVLMISIWSAFIPP DNKCVFRTFCVF*GINKAFDNIKYKM

Frame 2

GGFARESRGRRAARSPPPAPWQPPAPQLSTATS GPSWASRSWDNWTAPAWRCPPRPS*SWRGAAAA AARQSRACGSRSRCSRPSPGRAAAPWATEIFTE PAVFLSMSTTYTWLKMILLEAVPLFLKPMTC*RL AQLPLMKVAGEEEQHSTAPRSPWKKGP*GIL*G DWRFLLTAARRGLTTRTAITSTAREARLGTPCT TKKAGGPPS*CHRDMLVPRSWGSAVLAPQAGSAT LTHTTDSTSMALLATPFLTASLPTRPCSRTPGQ GPAAAWATSWRRRTT*RQGSLSGRSGRWCPCSP SLRTGLPGPPGIRAPSTAPAR*GKLGPVSPWIPA GGERT*LSARRPQGEVGICSLREALSLTPSWGM QTWR*LWSEQ*VCSRQTTCCHPGFLLQLLSYST SASRNLKLGRGLTSFVASSSFCSS*KFRMKTFSE LCVGP*ET*YLKTMTTNWRWLN*MGYLGCSRC* SKPETWRLKNK*QTIQSI*EVGMAGRARWLTPV IPALWEAKAGGSRGQEFETSLTNMVCCGICHLMT NSRIS**QKHCLR*RRISSSPFLGGLKETTQKQ MVCSILTYSTTSLDA*ET*VLLALMGEKR*EDV TDSLTHWSIMSEEPLQITSQMTRPRRIVCAFFIT SPTSWRQSSQRNIPRISIFKTGISRLTTTKVLD VLAVEAGK*KSNTRTCRCRRKRATPRAWSGCGI PLL*GCICP*SPKVSATTHKKHP*ELCRTSRPEV DQCRHQWLRQLSRRKVACSTPERCCMLVTQV*K RQPSRC*GICPGIFLCRMKLPKKLSLIWFPSFL TQSRVLTFSLKLQPLPVTH*TT*SKTVTRMHATF *TPGASRKLWPLVQAMPMPPTKQVKLLPSFCIL CGHTRNCIMPTRRLSLRRQILSTAGLPKPTTPL KTEENDKVFSAAKIPKGKHLFFYYPAQETSKACL VSILLYFRGPLNPENK*NIIL*VFQKTFASLPP VDTGHRLDK*WSLLLGLMVHGFLESKCEFMWKG H*SNK*GKKLLHYWDFKSLIYIYIPFLVPMFCHS CAHCFAIGPPVYCSAVLKQNGNDKKYLQLSRRK YNGKIIGFFLYFVLVFIPLGCFSLIFK*T*EI* ITEYA*L*EKEIERK*S*QIKEVFSSQNLK*NKK *INK*NLFHRERQL***NLTFPQTLSQ*DFSQE ILYL*QRR*IQISSKRWHSM*CLSWTFLATALD **KNGLYLYLQEELRPSLRLPGQPGALKIRLMLM SYIISQPSLAHHLRNITEPLDLI*SSSSHYFNS RKL*RRKVKKSC*RRCKNVSRPSRNDMRNTDIL NG*HHPAK*IYIKCCFNCAMIKTIHIELVFTTTI LLFFFLI*QHLS*VR*AKKFFNSFWQENCNRK* ILNVYLSLYYI*SNFFSILKAE*RQLRLLT*FK MKLFRYQFLKYWREFICLFPEF***AFGVHLFLQ IINVCSELFVFFKALIKPSIILNTK*