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Sequences

Sequence NM_001005337

GGGTGGTGCAGGGCAGGGGTGGTATATCCTGTCTGACGGAGGGCGGGCCTCGCCAGTGCCAGAGAGGGACGAACCAGGGTGGAAGCGCCAGGAGCAGCTG CAGGGAGCCCTCACGCGGACCACGCACTCTATGGCCGTAGGGAGCCGCTGAGAGCGAGAAGAGCACGCTCCTGCCCGCCCGCTGCACCGCACCTCGCCTC GCCTCTCTGCTCTCCTAGGCCCCGGCCGCGCGCCACCCGCCTCCCGCCACCATGAACCACTCGCCGCTCAAGACCGCCTTGGCGTACGAATGCTTCCAGG ACCAGGACAACTCCACGTTGGCTTTGCCGTCGGACCAAAAGATGAAAACAGGCACGTCTGGCAGGCAGCGCGTGCAGGAGCAGGTGATGATGACCGTCAA GCGGCAGAAGTCCAAGTCTTCCCAGTCGTCCACCCTGAGCCACTCCAATCGAGGTTCCATGTATGATGGCTTGGCTGACAATTACAACTATGGGACCACC AGCAGGAGCAGCTACTACTCCAAGTTCCAGGCAGGGAATGGCTCATGGGGATATCCGATCTACAATGGAACCCTCAAGCGGGAGCCTGACAACAGGCGCT TCAGCTCCTACAGCCAGATGGAGAACTGGAGCCGGCACTACCCCCGGGGCAGCTGTAACACCACCGGCGCAGGCAGCGACATCTGCTTCATGCAGAAAAT CAAGGCGAGCCGCAGTGAGCCCGACCTCTACTGTGACCCACGGGGCACCCTGCGCAAGGGCACGCTGGGCAGCAAGGGCCAGAAGACCACCCAGAACCGC TACAGCTTTTACAGCACCTGCAGTGGTCAGAAGGCCATAAAGAAGTGCCCTGTGCGCCCGCCCTCTTGTGCCTCCAAGCAGGACCCTGTGTATATCCCGC CCATCTCCTGCAACAAGGACCTGTCCTTTGGCCACTCTAGGGCCAGCTCCAAGATCTGCAGTGAGGACATCGAGTGCAGTGGGCTGACCATCCCCAAGGC TGTGCAGTACCTGAGCTCCCAGGATGAGAAATACCAGGCCATTGGGGCCTATTACATCCAGCATACCTGCTTCCAGGATGAATCTGCCAAGCAACAGGTC TATCAGCTGGGAGGCATCTGCAAGCTGGTGGACCTCCTCCGCAGCCCCAACCAGAACGTCCAGCAGGCCGCGGCAGGGGCCCTGCGCAACCTGGTGTTCA GGAGCACCACCAACAAGCTGGAGACCCGGAGGCAGAATGGGATCCGCGAGGCAGTCAGCCTCCTGAGGAGAACCGGGAACGCCGAGATCCAGAAGCAGCT GACTGGGCTGCTCTGGAACCTGTCTTCCACTGACGAGCTGAAGGAGGAACTCATTGCCGACGCCCTGCCTGTTCTGGCCGACCGCGTCATCATTCCCTTC TCTGGCTGGTGCGATGGCAATAGCAACATGTCCCGGGAAGTGGTGGACCCTGAGGTCTTCTTCAATGCCACAGGCTGCTTGAGGAACCTGAGCTCGGCCG ATGCAGGCCGCCAGACCATGCGTAACTACTCAGGGCTCATTGATTCCCTCATGGCCTATGTCCAGAACTGTGTAGCGGCCAGCCGCTGTGACGACAAGTC TGTGGAAAACTGCATGTGTGTTCTGCACAACCTCTCCTACCGCCTGGACGCCGAGGTGCCCACCCGCTACCGCCAGCTGGAGTATAACGCCCGCAACGCC TACACCGAGAAGTCCTCCACTGGCTGCTTCAGCAACAAGAGCGACAAGATGATGAACAACAACTATGACTGCCCCCTGCCTGAGGAAGAGACCAACCCCA AGGGCAGCGGCTGGTTGTACCATTCAGATGCCATCCGCACCTACCTGAACCTCATGGGCAAGAGCAAGAAAGATGCTACCCTGGAGGCCTGTGCTGGTGC CCTGCAGAACCTGACAGCCAGCAAGGGGCTGATGTCCAGTGGCATGAGCCAGTTGATTGGGCTGAAGGAAAAGGGCCTGCCACAAATTGCCCGCCTCCTG CAATCTGGCAACTCTGATGTGGTGCGGTCCGGAGCCTCCCTCCTGAGCAACATGTCCCGCCACCCTCTGCTGCACAGAGTGATGGGGAACCAGGTGTTCC CGGAGGTGACCAGGCTCCTCACCAGCCACACTGGCAATACCAGCAACTCCGAAGACATCTTGTCCTCGGCCTGCTACACTGTGAGGAACCTGATGGCCTC GCAGCCACAACTGGCCAAGCAGTACTTCTCCAGCAGCATGCTCAACAACATCATCAACCTGTGCCGAAGCAGTGCCTCACCCAAGGCCGCAGAAGCTGCC CGGCTTCTCCTGTCTGACATGTGGTCCAGCAAGGAACTGCAGGGTGTCCTCAGACAGCAAGGTTTCGATAGGAACATGCTGGGAACCTTAGCTGGGGCCA ACAGCCTCAGGAACTTCACCTCCCGATTCTAAGAAGAGACTGTCCAAGCAAGTTAGGCTTGCAGGAAGATATGACCCAGCTGAGAAGCCCTCAGGCCTCG CTGGATGGGGTTTTCTGTCCATCCTATGCAGTATTTGGGAAAGTTCACAAGAAACTGAGAAGAAACCTAAAAACTGTGGATAGTGGAAAGATTTTTAGAT TTTTTTTTTCCTTGGGGAAACTGGCAGGCAATGGGGGTTAGGGAGGTTGGGGCGGTGGGGGCTTTCTTGAGTTAAAGGGGCTTATATGTGATGTCAATAT TTCTTCCTCTGAGAAATGGTATATATATGTGTATAATGTAAGTGTGTGCATGCATGTGCGCGTGCATGTGTGTGTGTGTGAGTGTCTTAAAGCATAACCA CAAACTGCAAAAAGCTAGGTAAGCTATTTTGTTGCAGCTCATAAGGTGGTGAAAAGGACTCTCCTGTGTTTCTTACTCATAGGCAAGGACAACATGTGCT TTTTGGTGAGCTGCTCATAATTCCTGAAATGTGTGGTGCCAGGGCAAGGGGGCCATCACTGCAGTCAGGCCCTCAGAGGAGTCCTGCAGGCTTCCTACCA GTGGTCTCCAGGGGTGCAGGAGTAACTGGGGCTGGGCCAGCCTCCCCACTTACAAGGCTGCTTTCCAGGAAGGGAGGTCTGGTGTATCTCATGGGAGAAT CTGGGGTGTCTGTAATGTCACCCCTCCAGCAGCGCCACAAGGACTGAGGTTGGGTAGGTGTGGGGTTCCAGAGGACAGCAGGACACTCTCGCATACTTTG CCAAATGAGGCCTGCTCAGAGGAGTAGGAGCTGAAAGATGGTGCCTTCCACCCTCTTGGGCTGTGTGCCCATCAGAGCAGGCTCAGCCTGCAAAGGCCCT GCATTCAGAGGTCTTGTAATCTACTTGTTGCAGGAGAAAGAAGGTAAAAAATGATTTTTTTAAGAAAAGCTATTTTATTGCAGCTCTTTCCCAAGAGCTG TTCTGGGAATGGCTGGTCTTCATATTCCCAGTGGAGAGGGGAACAAGTGGGGCTGGGCATATACCTATTCCGGCTTCTAGTGGGATGGAGTTGGGGTATA GAAATTAACCAGGAAGATGTTTCCACCAAGCCTGCTGTGAGTCAATTGAGGGAGTGTTTGGGGTCCCAGGAGACTTGGACGGGGGGAGTTTGGGTAGACT AGGAAAGGAAAGTGCCATATCAGGGTACCGGTACCGGCAAGCTCACATCTCAGCCAGGGGCCATGCCCCACTTCCCCTGACCCCAGCTGTCTTGTCTCCA CTCTGTGAAACCCACAGGGGATGTGATAAACAGGGCTATTAGGGGTATCAGCCACGTCGAGCCCCCAGACTCTGTGCACTTCAGACCAGCAGCAGCAGGA GGGCTCCCGAGGGCCTTATGAGAAAACCTGTGTGGACATCCCTTGGTGTACACTAAGACAGAGCAGAGCCCAGCGCTCCCAAGCCTTCCTCCTTCCAGCT TCTACCTCCATGCTAGCATTGCTGGTGTTAGAGAGGAATTAACTTCCTGGTCTGTGCCCTTCTCTAGAAGAATATAAGATGCTCCTCCTCCTCACCCCTT CTCAGCCTCCTCCCAAGTCTTCCTCTTCTGCACCACCCCCGAGTCCAAACCCACCTCTTGCCCCAGCATTCAGGCTGGAAAACACTGATGTGGACTCAGT ATGATAACTGAGATGGGGGACGCCAGACATGTGAGGACGCTGTCCTCCGAGAGGTGTCCCCGGCTGTTAGCCAGCTGTGCTGTGGTGCTGTGGGTCTGTC ATACCCTCCCTTGCTTCTGTTCACACTGGGAGGCCCACTCCTGGCTCACCTCTCCCTCTCAGGGACCCACGTGGGAGCCTGGATCCCTGGACTGTCCTGG GCATAGGTTTCAGGGGCCTCCTTTGTTGTCATCAGAACCCAGAGGAATTCTTCTCCTAAAAAATACGTATGGCATACCAATCTGTGCGGGGCAGTGTCCT AAGCACTTAGACTACATCAGGGAAGAACACAGACCACATCCCTGTCCTCATGCGGCTTATGTTTTCTGGAGGAAAGTGGAGACACAAGTCCTTGGCTTTA GGGCTCCCCCGGCTGGGGGCTGTGCAGTCCGGTCAGGGCGGGAGGGGAAATGCACCGCTGCATGTGAACCTTACCAGCCCAGGCGGATGCCCCTTCCCCT TAGCACTACCCTGGCCTCCTGCATCCCCTCGCCTCATGTTCCTCCCACCTTCAAAGAATGAAGAGCCCCATGGGCCCAGCCCCTGCCCTGGGAACCAGGC AGCCTTCCAGACCTCAGGGGCTGAGGCAGACTATTAGGGCAGGGCTGACTTTGGTGACACTGCCCATTCCCTCTCAGGCCAGCTCAGGTCACCCGGGCCT CTGACCCAGGCCTGTCACTTTGAGAGGGGCAAAACTGAGAGGGGCTTTTCCTAGAGAAAGAGAACAAGGAGCTTGCCAGGCTTCATGTAGCCGACACACG TCTCAGGATTTTAAGTCCACATTGGCCTCACACTACCAGGGCCAATGCCCAAAATAAGGAGTTCCAATTTGGGGCCAAATGAGGAAGGACACAGACTCTG CCCTGGGATCTCCTGTGCTAGCGGCCAATGACAAATCCAGTCATTGGCCACCAGCCACCTCTGCAGTGGGGACCACACTAGCAGCCCTGACTCCACACTC CTCCTGGGGACCCAAGAGGCAGTGTTGCTGTCTGCATGTCCACCTTGGAATCTGGCTGAACTGGCTGGCAGGACCAAGACTGCGGCTGGGGTGGGCAGGG AAGGGAAGCCGGGGGCTGCTGTGAGGGATCTTGGAGCTTCCCTGTAGCCCACCTTCCCCTTGCTTCATGTTTGTAGAGGAACCTTGTGCCGGCCAGGCCC AGTTTCCTTGTGTGATACACTAATGTATTTGCTTTTTTTGGAAATAGAGAAAATCAATAAATTGCTAGTGTTTCTTTGAA

refseq_PKP1.F1 (forward primer)
refseq_PKP1.R1 (reverse primer)
Single exon skipping

Frame 0

GWCRAGVVYPV*RRAGLASAREGRTRVEAPGAA AGSPHADHALYGRREPLRARRARSCPPAAPHLAS PLCSPRPRPRATRLPPP*TTRRSRPPWRTNASR TRTTPRWLCRRTKR*KQARLAGSACRSR***PS SGRSPSLPSRPP*ATPIEVPCMMAWLTITTMGPP AGAATTPSSRQGMAHGDIRSTMEPSSGSLTTGA SAPTARWRTGAGTTPGAAVTPPAQAATSASCRK SRRAAVSPTSTVTHGAPCARARWAARARRPPRTA TAFTAPAVVRRP*RSALCARPLVPPSRTLCISR PSPATRTCPLATLGPAPRSAVRTSSAVG*PSPR LCST*APRMRNTRPLGPITSSIPASRMNLPSNRS ISWEASASWWTSSAAPTRTSSRPRQGPCATWCS GAPPTSWRPGGRMGSARQSAS*GEPGTPRSRSS *LGCSGTCLPLTS*RRNSLPTPCLFWPTASSFPS LAGAMAIATCPGKWWTLRSSSMPQAA*GT*ARP MQAARPCVTTQGSLIPSWPMSRTV*RPAAVTTS LWKTACVFCTTSPTAWTPRCPPATASWSITPATP TPRSPPLAASATRATR**TTTMTAPCLRKRPTP RAAAGCTIQMPSAPT*TSWARARKMLPWRPVLV PCRT*QPARG*CPVA*AS*LG*RKRACHKLPASC NLATLMWCGPEPPS*ATCPATLCCTE*WGTRCS RR*PGSSPATLAIPATPKTSCPRPATL*GT*WP RSHNWPSSTSPAACSTTSSTCAEAVPHPRPQKLP GFSCLTCGPARNCRVSSDSKVSIGTCWEP*LGP TASGTSPPDSKKRLSKQVRLAGRYDPAEKPSGL AGWGFLSILCSIWESSQETEKKPKNCG*WKDF*I FFFLGETGRQWGLGRLGRWGLS*VKGAYM*CQY FFL*EMVYICV*CKCVHACARACVCV*VS*SIT TNCKKLGKLFCCSS*GGEKDSPVFLTHRQGQHVL FGELLIIPEMCGARARGPSLQSGPQRSPAGFLP VVSRGAGVTGAGPASPLTRLLSRKGGLVYLMGE SGVSVMSPLQQRHKD*GWVGVGFQRTAGHSRILC QMRPAQRSRS*KMVPSTLLGCVPIRAGSACKGP AFRGLVIYLLQEKEGKK*FF*EKLFYCSSFPRA VLGMAGLHIPSGEGNKWGWAYTYSGF*WDGVGV* KLTRKMFPPSLL*VN*GSVWGPRRLGRGEFG*T RKGKCHIRVPVPASSHLSQGPCPTSPDPSCLVS TL*NPQGM**TGLLGVSATSSPQTLCTSDQQQQE GSRGPYEKTCVDIPWCTLRQSRAQRSQAFLLPA STSMLALLVLERN*LPGLCPSLEEYKMLLLLTP SQPPPKSSSSAPPPSPNPPLAPAFRLENTDVDSV **LRWGTPDM*GRCPPRGVPGC*PAVLWCCGSV IPSLASVHTGRPTPGSPLPLRDPRGSLDPWTVL GIGFRGLLCCHQNPEEFFS*KIRMAYQSVRGSVL ST*TTSGKNTDHIPVLMRLMFSGGKWRHKSLAL GLPRLGAVQSGQGGRGNAPLHVNLTSPGGCPFP LALPWPPASPRLMFLPPSKNEEPHGPSPCPGNQA AFQTSGAEADY*GRADFGDTAHSLSGQLRSPGP LTQACHFERGKTERGFS*RKRTRSLPGFM*PTH VSGF*VHIGLTLPGPMPKIRSSNLGPNEEGHRLC PGISCASGQ*QIQSLATSHLCSGDHTSSPDSTL LLGTQEAVLLSACPPWNLAELAGRTKTAAGVGR EGKPGAAVRDLGASL*PTFPLLHVCRGTLCRPGP VSLCDTLMYLLFLEIEKINKLLVFL*

Frame 1

GGAGQGWYILSDGGRASPVPERDEPGWKRQEQL QGALTRTTHSMAVGSR*EREEHAPARPLHRTSP RLSALLGPGRAPPASRHHEPLAAQDRLGVRMLPG PGQLHVGFAVGPKDENRHVWQAARAGAGDDDRQ AAEVQVFPVVHPEPLQSRFHV*WLG*QLQLWDH QQEQLLLQVPGREWLMGISDLQWNPQAGA*QQAL QLLQPDGELEPALPPGQL*HHRRRQRHLLHAEN QGEPQ*ARPLL*PTGHPAQGHAGQQGPEDHPEP LQLLQHLQWSEGHKEVPCAPALLCLQAGPCVYPA HLLQQGPVLWPL*GQLQDLQ*GHRVQWADHPQG CAVPELPG*EIPGHWGLLHPAYLLPG*ICQATG LSAGRHLQAGGPPPQPQPERPAGRGRGPAQPGVQ EHHQQAGDPEAEWDPRGSQPPEENRERRDPEAA DWAALEPVFH*RAEGGTHCRRPACSGRPRHHSL LWLVRWQ*QHVPGSGGP*GLLQCHRLLEEPELGR CRPPDHA*LLRAH*FPHGLCPELCSGQPL*RQV CGKLHVCSAQPLLPPGRRGAHPLPPAGV*RPQR LHREVLHWLLQQQERQDDEQQL*LPPA*GRDQPQ GQRLVVPFRCHPHLPEPHGQEQERCYPGGLCWC PAEPDSQQGADVQWHEPVDWAEGKGPATNCPPP AIWQL*CGAVRSLPPEQHVPPPSAAQSDGEPGVP GGDQAPHQPHWQYQQLRRHLVLGLLHCEEPDGL AATTGQAVLLQQHAQQHHQPVPKQCLTQGRRSC PASPV*HVVQQGTAGCPQTARFR*EHAGNLSWGQ QPQELHLPILRRDCPSKLGLQEDMTQLRSPQAS LDGVFCPSYAVFGKVHKKLRRNLKTVDSGKIFR FFFSLGKLAGNGG*GGWGGGGFLELKGLICDVNI SSSEKWYIYVYNVSVCMHVRVHVCVCECLKA*P QTAKS*VSYFVAAHKVVKRTLLCFLLIGKDNMC FLVSCS*FLKCVVPGQGGHHCSQALRGVLQASYQ WSPGVQE*LGLGQPPHLQGCFPGREVWCISWEN LGCL*CHPSSSATRTEVG*VWGSRGQQDTLAYF AK*GLLRGVGAERWCLPPSWAVCPSEQAQPAKAL HSEVL*STCCRRKKVKNDFFKKSYFIAALSQEL FWEWLVFIFPVERGTSGAGHIPIPASSGMELGY RN*PGRCFHQACCESIEGVFGVPGDLDGGSLGRL GKESAISGYRYRQAHISARGHAPLPLTPAVLSP LCETHRGCDKQGY*GYQPRRAPRLCALQTSSSR RAPEGLMRKPVWTSLGVH*DRAEPSAPKPSSFQL LPPC*HCWC*RGINFLVCALL*KNIRCSSSSPL LSLLPSLPLLHHPRVQTHLLPQHSGWKTLMWTQ YDN*DGGRQTCEDAVLREVSPAVSQLCCGAVGLS YPPLLLFTLGGPLLAHLSLSGTHVGAWIPGLSW A*VSGASFVVIRTQRNSSPKKYVWHTNLCGAVS *ALRLHQGRTQTTSLSSCGLCFLEESGDTSPWL* GSPGWGLCSPVRAGGEMHRCM*TLPAQADAPSP *HYPGLLHPLASCSSHLQRMKSPMGPAPALGTR QPSRPQGLRQTIRAGLTLVTLPIPSQASSGHPGL *PRPVTLRGAKLRGAFPREREQGACQASCSRHT SQDFKSTLASHYQGQCPK*GVPIWGQMRKDTDS ALGSPVLAANDKSSHWPPATSAVGTTLAALTPHS SWGPKRQCCCLHVHLGIWLNWLAGPRLRLGWAG KGSRGLL*GILELPCSPPSPCFMFVEEPCAGQA QFPCVIH*CICFFWK*RKSINC*CFFE

Frame 2

VVQGRGGISCLTEGGPRQCQRGTNQGGSARSSC REPSRGPRTLWP*GAAESEKSTLLPARCTAPRL ASLLS*APAARHPPPATMNHSPLKTALAYECFQ DQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVK RQKSKSSQSSTLSHSNRGSMYDGLADNYNYGTT SRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRR FSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKI KASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNR YSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIP PISCNKDLSFGHSRASSKICSEDIECSGLTIPKA VQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQV YQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL TGLLWNLSSTDELKEELIADALPVLADRVIIPF SGWCDGNSNMSREVVDPEVFFNATGCLRNLSSA DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKS VENCMCVLHNLSYRLDAEVPTRYRQLEYNARNA YTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNP KGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGA LQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL QSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVF PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA RLLLSDMWSSKELQGVLRQQGFDRNMLGTLAGA NSLRNFTSRF*EETVQAS*ACRKI*PS*EALRPR WMGFSVHPMQYLGKFTRN*EET*KLWIVERFLD FFFPWGNWQAMGVREVGAVGAFLS*RGLYVMSI FLPLRNGIYMCIM*VCACMCACMCVCVSVLKHNH KLQKAR*AILLQLIRW*KGLSCVSYS*ARTTCA FW*AAHNS*NVWCQGKGAITAVRPSEESCRLPT SGLQGCRSNWGWASLPTYKAAFQEGRSGVSHGRI WGVCNVTPPAAPQGLRLGRCGVPEDSRTLSHTL PNEACSEE*ELKDGAFHPLGLCAHQSRLSLQRP CIQRSCNLLVAGERR*KMIFLRKAILLQLFPKSC SGNGWSSYSQWRGEQVGLGIYLFRLLVGWSWGI EINQEDVSTKPAVSQLRECLGSQETWTGGVWVD *ERKVPYQGTGTGKLTSQPGAMPHFP*PQLSCLH SVKPTGDVINRAIRGISHVEPPDSVHFRPAAAG GLPRAL*ENLCGHPLVYTKTEQSPALPSLPPSS FYLHASIAGVREELTSWSVPFSRRI*DAPPPHPF SASSQVFLFCTTPESKPTSCPSIQAGKH*CGLS MITEMGDARHVRTLSSERCPRLLASCAVVLWVC HTLPCFCSHWEAHSWLTSPSQGPTWEPGSLDCPG HRFQGPPLLSSEPRGILLLKNTYGIPICAGQCP KHLDYIREEHRPHPCPHAAYVFWRKVETQVLGF RAPPAGGCAVRSGREGKCTAACEPYQPRRMPLPL STTLASCIPSPHVPPTFKE*RAPWAQPLPWEPG SLPDLRG*GRLLGQG*LW*HCPFPLRPAQVTRA SDPGLSL*EGQN*EGLFLEKENKELARLHVADTR LRILSPHWPHTTRANAQNKEFQFGAK*GRTQTL PWDLLC*RPMTNPVIGHQPPLQWGPH*QP*LHT PPGDPRGSVAVCMSTLESG*TGWQDQDCGWGGQG REAGGCCEGSWSFPVAHLPLASCL*RNLVPARP SFLV*YTNVFAFFGNRENQ*IASVSL

Sequence NM_000299

GGGTGGTGCAGGGCAGGGGTGGTATATCCTGTCTGACGGAGGGCGGGCCTCGCCAGTGCCAGAGAGGGACGAACCAGGGTGGAAGCGCCAGGAGCAGCTG CAGGGAGCCCTCACGCGGACCACGCACTCTATGGCCGTAGGGAGCCGCTGAGAGCGAGAAGAGCACGCTCCTGCCCGCCCGCTGCACCGCACCTCGCCTC GCCTCTCTGCTCTCCTAGGCCCCGGCCGCGCGCCACCCGCCTCCCGCCACCATGAACCACTCGCCGCTCAAGACCGCCTTGGCGTACGAATGCTTCCAGG ACCAGGACAACTCCACGTTGGCTTTGCCGTCGGACCAAAAGATGAAAACAGGCACGTCTGGCAGGCAGCGCGTGCAGGAGCAGGTGATGATGACCGTCAA GCGGCAGAAGTCCAAGTCTTCCCAGTCGTCCACCCTGAGCCACTCCAATCGAGGTTCCATGTATGATGGCTTGGCTGACAATTACAACTATGGGACCACC AGCAGGAGCAGCTACTACTCCAAGTTCCAGGCAGGGAATGGCTCATGGGGATATCCGATCTACAATGGAACCCTCAAGCGGGAGCCTGACAACAGGCGCT TCAGCTCCTACAGCCAGATGGAGAACTGGAGCCGGCACTACCCCCGGGGCAGCTGTAACACCACCGGCGCAGGCAGCGACATCTGCTTCATGCAGAAAAT CAAGGCGAGCCGCAGTGAGCCCGACCTCTACTGTGACCCACGGGGCACCCTGCGCAAGGGCACGCTGGGCAGCAAGGGCCAGAAGACCACCCAGAACCGC TACAGCTTTTACAGCACCTGCAGTGGTCAGAAGGCCATAAAGAAGTGCCCTGTGCGCCCGCCCTCTTGTGCCTCCAAGCAGGACCCTGTGTATATCCCGC CCATCTCCTGCAACAAGGACCTGTCCTTTGGCCACTCTAGGGCCAGCTCCAAGATCTGCAGTGAGGACATCGAGTGCAGTGGGCTGACCATCCCCAAGGC TGTGCAGTACCTGAGCTCCCAGGATGAGAAATACCAGGCCATTGGGGCCTATTACATCCAGCATACCTGCTTCCAGGATGAATCTGCCAAGCAACAGGTC TATCAGCTGGGAGGCATCTGCAAGCTGGTGGACCTCCTCCGCAGCCCCAACCAGAACGTCCAGCAGGCCGCGGCAGGGGCCCTGCGCAACCTGGTGTTCA GGAGCACCACCAACAAGCTGGAGACCCGGAGGCAGAATGGGATCCGCGAGGCAGTCAGCCTCCTGAGGAGAACCGGGAACGCCGAGATCCAGAAGCAGCT GACTGGGCTGCTCTGGAACCTGTCTTCCACTGACGAGCTGAAGGAGGAACTCATTGCCGACGCCCTGCCTGTTCTGGCCGACCGCGTCATCATTCCCTTC TCTGGCTGGTGCGATGGCAATAGCAACATGTCCCGGGAAGTGGTGGACCCTGAGGTCTTCTTCAATGCCACAGGCTGCTTGAGAAAGAGACTGGGCATGC GGGAGCTTCTGGCTCTTGTTCCGCAAAGGGCCACTAGTAGCAGGGTGAACCTGAGCTCGGCCGATGCAGGCCGCCAGACCATGCGTAACTACTCAGGGCT CATTGATTCCCTCATGGCCTATGTCCAGAACTGTGTAGCGGCCAGCCGCTGTGACGACAAGTCTGTGGAAAACTGCATGTGTGTTCTGCACAACCTCTCC TACCGCCTGGACGCCGAGGTGCCCACCCGCTACCGCCAGCTGGAGTATAACGCCCGCAACGCCTACACCGAGAAGTCCTCCACTGGCTGCTTCAGCAACA AGAGCGACAAGATGATGAACAACAACTATGACTGCCCCCTGCCTGAGGAAGAGACCAACCCCAAGGGCAGCGGCTGGTTGTACCATTCAGATGCCATCCG CACCTACCTGAACCTCATGGGCAAGAGCAAGAAAGATGCTACCCTGGAGGCCTGTGCTGGTGCCCTGCAGAACCTGACAGCCAGCAAGGGGCTGATGTCC AGTGGCATGAGCCAGTTGATTGGGCTGAAGGAAAAGGGCCTGCCACAAATTGCCCGCCTCCTGCAATCTGGCAACTCTGATGTGGTGCGGTCCGGAGCCT CCCTCCTGAGCAACATGTCCCGCCACCCTCTGCTGCACAGAGTGATGGGGAACCAGGTGTTCCCGGAGGTGACCAGGCTCCTCACCAGCCACACTGGCAA TACCAGCAACTCCGAAGACATCTTGTCCTCGGCCTGCTACACTGTGAGGAACCTGATGGCCTCGCAGCCACAACTGGCCAAGCAGTACTTCTCCAGCAGC ATGCTCAACAACATCATCAACCTGTGCCGAAGCAGTGCCTCACCCAAGGCCGCAGAAGCTGCCCGGCTTCTCCTGTCTGACATGTGGTCCAGCAAGGAAC TGCAGGGTGTCCTCAGACAGCAAGGTTTCGATAGGAACATGCTGGGAACCTTAGCTGGGGCCAACAGCCTCAGGAACTTCACCTCCCGATTCTAAGAAGA GACTGTCCAAGCAAGTTAGGCTTGCAGGAAGATATGACCCAGCTGAGAAGCCCTCAGGCCTCGCTGGATGGGGTTTTCTGTCCATCCTATGCAGTATTTG GGAAAGTTCACAAGAAACTGAGAAGAAACCTAAAAACTGTGGATAGTGGAAAGATTTTTAGATTTTTTTTTTCCTTGGGGAAACTGGCAGGCAATGGGGG TTAGGGAGGTTGGGGCGGTGGGGGCTTTCTTGAGTTAAAGGGGCTTATATGTGATGTCAATATTTCTTCCTCTGAGAAATGGTATATATATGTGTATAAT GTAAGTGTGTGCATGCATGTGCGCGTGCATGTGTGTGTGTGTGAGTGTCTTAAAGCATAACCACAAACTGCAAAAAGCTAGGTAAGCTATTTTGTTGCAG CTCATAAGGTGGTGAAAAGGACTCTCCTGTGTTTCTTACTCATAGGCAAGGACAACATGTGCTTTTTGGTGAGCTGCTCATAATTCCTGAAATGTGTGGT GCCAGGGCAAGGGGGCCATCACTGCAGTCAGGCCCTCAGAGGAGTCCTGCAGGCTTCCTACCAGTGGTCTCCAGGGGTGCAGGAGTAACTGGGGCTGGGC CAGCCTCCCCACTTACAAGGCTGCTTTCCAGGAAGGGAGGTCTGGTGTATCTCATGGGAGAATCTGGGGTGTCTGTAATGTCACCCCTCCAGCAGCGCCA CAAGGACTGAGGTTGGGTAGGTGTGGGGTTCCAGAGGACAGCAGGACACTCTCGCATACTTTGCCAAATGAGGCCTGCTCAGAGGAGTAGGAGCTGAAAG ATGGTGCCTTCCACCCTCTTGGGCTGTGTGCCCATCAGAGCAGGCTCAGCCTGCAAAGGCCCTGCATTCAGAGGTCTTGTAATCTACTTGTTGCAGGAGA AAGAAGGTAAAAAATGATTTTTTTAAGAAAAGCTATTTTATTGCAGCTCTTTCCCAAGAGCTGTTCTGGGAATGGCTGGTCTTCATATTCCCAGTGGAGA GGGGAACAAGTGGGGCTGGGCATATACCTATTCCGGCTTCTAGTGGGATGGAGTTGGGGTATAGAAATTAACCAGGAAGATGTTTCCACCAAGCCTGCTG TGAGTCAATTGAGGGAGTGTTTGGGGTCCCAGGAGACTTGGACGGGGGGAGTTTGGGTAGACTAGGAAAGGAAAGTGCCATATCAGGGTACCGGTACCGG CAAGCTCACATCTCAGCCAGGGGCCATGCCCCACTTCCCCTGACCCCAGCTGTCTTGTCTCCACTCTGTGAAACCCACAGGGGATGTGATAAACAGGGCT ATTAGGGGTATCAGCCACGTCGAGCCCCCAGACTCTGTGCACTTCAGACCAGCAGCAGCAGGAGGGCTCCCGAGGGCCTTATGAGAAAACCTGTGTGGAC ATCCCTTGGTGTACACTAAGACAGAGCAGAGCCCAGCGCTCCCAAGCCTTCCTCCTTCCAGCTTCTACCTCCATGCTAGCATTGCTGGTGTTAGAGAGGA ATTAACTTCCTGGTCTGTGCCCTTCTCTAGAAGAATATAAGATGCTCCTCCTCCTCACCCCTTCTCAGCCTCCTCCCAAGTCTTCCTCTTCTGCACCACC CCCGAGTCCAAACCCACCTCTTGCCCCAGCATTCAGGCTGGAAAACACTGATGTGGACTCAGTATGATAACTGAGATGGGGGACGCCAGACATGTGAGGA CGCTGTCCTCCGAGAGGTGTCCCCGGCTGTTAGCCAGCTGTGCTGTGGTGCTGTGGGTCTGTCATACCCTCCCTTGCTTCTGTTCACACTGGGAGGCCCA CTCCTGGCTCACCTCTCCCTCTCAGGGACCCACGTGGGAGCCTGGATCCCTGGACTGTCCTGGGCATAGGTTTCAGGGGCCTCCTTTGTTGTCATCAGAA CCCAGAGGAATTCTTCTCCTAAAAAATACGTATGGCATACCAATCTGTGCGGGGCAGTGTCCTAAGCACTTAGACTACATCAGGGAAGAACACAGACCAC ATCCCTGTCCTCATGCGGCTTATGTTTTCTGGAGGAAAGTGGAGACACAAGTCCTTGGCTTTAGGGCTCCCCCGGCTGGGGGCTGTGCAGTCCGGTCAGG GCGGGAGGGGAAATGCACCGCTGCATGTGAACCTTACCAGCCCAGGCGGATGCCCCTTCCCCTTAGCACTACCCTGGCCTCCTGCATCCCCTCGCCTCAT GTTCCTCCCACCTTCAAAGAATGAAGAGCCCCATGGGCCCAGCCCCTGCCCTGGGAACCAGGCAGCCTTCCAGACCTCAGGGGCTGAGGCAGACTATTAG GGCAGGGCTGACTTTGGTGACACTGCCCATTCCCTCTCAGGCCAGCTCAGGTCACCCGGGCCTCTGACCCAGGCCTGTCACTTTGAGAGGGGCAAAACTG AGAGGGGCTTTTCCTAGAGAAAGAGAACAAGGAGCTTGCCAGGCTTCATGTAGCCGACACACGTCTCAGGATTTTAAGTCCACATTGGCCTCACACTACC AGGGCCAATGCCCAAAATAAGGAGTTCCAATTTGGGGCCAAATGAGGAAGGACACAGACTCTGCCCTGGGATCTCCTGTGCTAGCGGCCAATGACAAATC CAGTCATTGGCCACCAGCCACCTCTGCAGTGGGGACCACACTAGCAGCCCTGACTCCACACTCCTCCTGGGGACCCAAGAGGCAGTGTTGCTGTCTGCAT GTCCACCTTGGAATCTGGCTGAACTGGCTGGCAGGACCAAGACTGCGGCTGGGGTGGGCAGGGAAGGGAAGCCGGGGGCTGCTGTGAGGGATCTTGGAGC TTCCCTGTAGCCCACCTTCCCCTTGCTTCATGTTTGTAGAGGAACCTTGTGCCGGCCAGGCCCAGTTTCCTTGTGTGATACACTAATGTATTTGCTTTTT TTGGAAATAGAGAAAATCAATAAATTGCTAGTGTTTCTTTGAA

refseq_PKP1.F1 (forward primer)
refseq_PKP1.R1 (reverse primer)
Single exon skipping

Frame 0

GWCRAGVVYPV*RRAGLASAREGRTRVEAPGAA AGSPHADHALYGRREPLRARRARSCPPAAPHLAS PLCSPRPRPRATRLPPP*TTRRSRPPWRTNASR TRTTPRWLCRRTKR*KQARLAGSACRSR***PS SGRSPSLPSRPP*ATPIEVPCMMAWLTITTMGPP AGAATTPSSRQGMAHGDIRSTMEPSSGSLTTGA SAPTARWRTGAGTTPGAAVTPPAQAATSASCRK SRRAAVSPTSTVTHGAPCARARWAARARRPPRTA TAFTAPAVVRRP*RSALCARPLVPPSRTLCISR PSPATRTCPLATLGPAPRSAVRTSSAVG*PSPR LCST*APRMRNTRPLGPITSSIPASRMNLPSNRS ISWEASASWWTSSAAPTRTSSRPRQGPCATWCS GAPPTSWRPGGRMGSARQSAS*GEPGTPRSRSS *LGCSGTCLPLTS*RRNSLPTPCLFWPTASSFPS LAGAMAIATCPGKWWTLRSSSMPQAA*ERDWAC GSFWLLFRKGPLVAG*T*ARPMQAARPCVTTQG SLIPSWPMSRTV*RPAAVTTSLWKTACVFCTTSP TAWTPRCPPATASWSITPATPTPRSPPLAASAT RATR**TTTMTAPCLRKRPTPRAAAGCTIQMPS APT*TSWARARKMLPWRPVLVPCRT*QPARG*CP VA*AS*LG*RKRACHKLPASCNLATLMWCGPEP PS*ATCPATLCCTE*WGTRCSRR*PGSSPATLA IPATPKTSCPRPATL*GT*WPRSHNWPSSTSPAA CSTTSSTCAEAVPHPRPQKLPGFSCLTCGPARN CRVSSDSKVSIGTCWEP*LGPTASGTSPPDSKK RLSKQVRLAGRYDPAEKPSGLAGWGFLSILCSIW ESSQETEKKPKNCG*WKDF*IFFFLGETGRQWG LGRLGRWGLS*VKGAYM*CQYFFL*EMVYICV* CKCVHACARACVCV*VS*SITTNCKKLGKLFCCS S*GGEKDSPVFLTHRQGQHVLFGELLIIPEMCG ARARGPSLQSGPQRSPAGFLPVVSRGAGVTGAG PASPLTRLLSRKGGLVYLMGESGVSVMSPLQQRH KD*GWVGVGFQRTAGHSRILCQMRPAQRSRS*K MVPSTLLGCVPIRAGSACKGPAFRGLVIYLLQE KEGKK*FF*EKLFYCSSFPRAVLGMAGLHIPSGE GNKWGWAYTYSGF*WDGVGV*KLTRKMFPPSLL *VN*GSVWGPRRLGRGEFG*TRKGKCHIRVPVP ASSHLSQGPCPTSPDPSCLVSTL*NPQGM**TGL LGVSATSSPQTLCTSDQQQQEGSRGPYEKTCVD IPWCTLRQSRAQRSQAFLLPASTSMLALLVLER N*LPGLCPSLEEYKMLLLLTPSQPPPKSSSSAPP PSPNPPLAPAFRLENTDVDSV**LRWGTPDM*G RCPPRGVPGC*PAVLWCCGSVIPSLASVHTGRP TPGSPLPLRDPRGSLDPWTVLGIGFRGLLCCHQN PEEFFS*KIRMAYQSVRGSVLST*TTSGKNTDH IPVLMRLMFSGGKWRHKSLALGLPRLGAVQSGQ GGRGNAPLHVNLTSPGGCPFPLALPWPPASPRLM FLPPSKNEEPHGPSPCPGNQAAFQTSGAEADY* GRADFGDTAHSLSGQLRSPGPLTQACHFERGKT ERGFS*RKRTRSLPGFM*PTHVSGF*VHIGLTLP GPMPKIRSSNLGPNEEGHRLCPGISCASGQ*QI QSLATSHLCSGDHTSSPDSTLLLGTQEAVLLSA CPPWNLAELAGRTKTAAGVGREGKPGAAVRDLGA SL*PTFPLLHVCRGTLCRPGPVSLCDTLMYLLF LEIEKINKLLVFL*

Frame 1

GGAGQGWYILSDGGRASPVPERDEPGWKRQEQL QGALTRTTHSMAVGSR*EREEHAPARPLHRTSP RLSALLGPGRAPPASRHHEPLAAQDRLGVRMLPG PGQLHVGFAVGPKDENRHVWQAARAGAGDDDRQ AAEVQVFPVVHPEPLQSRFHV*WLG*QLQLWDH QQEQLLLQVPGREWLMGISDLQWNPQAGA*QQAL QLLQPDGELEPALPPGQL*HHRRRQRHLLHAEN QGEPQ*ARPLL*PTGHPAQGHAGQQGPEDHPEP LQLLQHLQWSEGHKEVPCAPALLCLQAGPCVYPA HLLQQGPVLWPL*GQLQDLQ*GHRVQWADHPQG CAVPELPG*EIPGHWGLLHPAYLLPG*ICQATG LSAGRHLQAGGPPPQPQPERPAGRGRGPAQPGVQ EHHQQAGDPEAEWDPRGSQPPEENRERRDPEAA DWAALEPVFH*RAEGGTHCRRPACSGRPRHHSL LWLVRWQ*QHVPGSGGP*GLLQCHRLLEKETGHA GASGSCSAKGH**QGEPELGRCRPPDHA*LLRA H*FPHGLCPELCSGQPL*RQVCGKLHVCSAQPL LPPGRRGAHPLPPAGV*RPQRLHREVLHWLLQQQ ERQDDEQQL*LPPA*GRDQPQGQRLVVPFRCHP HLPEPHGQEQERCYPGGLCWCPAEPDSQQGADV QWHEPVDWAEGKGPATNCPPPAIWQL*CGAVRSL PPEQHVPPPSAAQSDGEPGVPGGDQAPHQPHWQ YQQLRRHLVLGLLHCEEPDGLAATTGQAVLLQQ HAQQHHQPVPKQCLTQGRRSCPASPV*HVVQQGT AGCPQTARFR*EHAGNLSWGQQPQELHLPILRR DCPSKLGLQEDMTQLRSPQASLDGVFCPSYAVF GKVHKKLRRNLKTVDSGKIFRFFFSLGKLAGNGG *GGWGGGGFLELKGLICDVNISSSEKWYIYVYN VSVCMHVRVHVCVCECLKA*PQTAKS*VSYFVA AHKVVKRTLLCFLLIGKDNMCFLVSCS*FLKCVV PGQGGHHCSQALRGVLQASYQWSPGVQE*LGLG QPPHLQGCFPGREVWCISWENLGCL*CHPSSSA TRTEVG*VWGSRGQQDTLAYFAK*GLLRGVGAER WCLPPSWAVCPSEQAQPAKALHSEVL*STCCRR KKVKNDFFKKSYFIAALSQELFWEWLVFIFPVE RGTSGAGHIPIPASSGMELGYRN*PGRCFHQACC ESIEGVFGVPGDLDGGSLGRLGKESAISGYRYR QAHISARGHAPLPLTPAVLSPLCETHRGCDKQG Y*GYQPRRAPRLCALQTSSSRRAPEGLMRKPVWT SLGVH*DRAEPSAPKPSSFQLLPPC*HCWC*RG INFLVCALL*KNIRCSSSSPLLSLLPSLPLLHH PRVQTHLLPQHSGWKTLMWTQYDN*DGGRQTCED AVLREVSPAVSQLCCGAVGLSYPPLLLFTLGGP LLAHLSLSGTHVGAWIPGLSWA*VSGASFVVIR TQRNSSPKKYVWHTNLCGAVS*ALRLHQGRTQTT SLSSCGLCFLEESGDTSPWL*GSPGWGLCSPVR AGGEMHRCM*TLPAQADAPSP*HYPGLLHPLAS CSSHLQRMKSPMGPAPALGTRQPSRPQGLRQTIR AGLTLVTLPIPSQASSGHPGL*PRPVTLRGAKL RGAFPREREQGACQASCSRHTSQDFKSTLASHY QGQCPK*GVPIWGQMRKDTDSALGSPVLAANDKS SHWPPATSAVGTTLAALTPHSSWGPKRQCCCLH VHLGIWLNWLAGPRLRLGWAGKGSRGLL*GILE LPCSPPSPCFMFVEEPCAGQAQFPCVIH*CICFF WK*RKSINC*CFFE

Frame 2

VVQGRGGISCLTEGGPRQCQRGTNQGGSARSSC REPSRGPRTLWP*GAAESEKSTLLPARCTAPRL ASLLS*APAARHPPPATMNHSPLKTALAYECFQ DQDNSTLALPSDQKMKTGTSGRQRVQEQVMMTVK RQKSKSSQSSTLSHSNRGSMYDGLADNYNYGTT SRSSYYSKFQAGNGSWGYPIYNGTLKREPDNRR FSSYSQMENWSRHYPRGSCNTTGAGSDICFMQKI KASRSEPDLYCDPRGTLRKGTLGSKGQKTTQNR YSFYSTCSGQKAIKKCPVRPPSCASKQDPVYIP PISCNKDLSFGHSRASSKICSEDIECSGLTIPKA VQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQV YQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQL TGLLWNLSSTDELKEELIADALPVLADRVIIPF SGWCDGNSNMSREVVDPEVFFNATGCLRKRLGM RELLALVPQRATSSRVNLSSADAGRQTMRNYSGL IDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSN KSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIR TYLNLMGKSKKDATLEACAGALQNLTASKGLMS SGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGA SLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGN TSNSEDILSSACYTVRNLMASQPQLAKQYFSSS MLNNIINLCRSSASPKAAEAARLLLSDMWSSKE LQGVLRQQGFDRNMLGTLAGANSLRNFTSRF*EE TVQAS*ACRKI*PS*EALRPRWMGFSVHPMQYL GKFTRN*EET*KLWIVERFLDFFFPWGNWQAMG VREVGAVGAFLS*RGLYVMSIFLPLRNGIYMCIM *VCACMCACMCVCVSVLKHNHKLQKAR*AILLQ LIRW*KGLSCVSYS*ARTTCAFW*AAHNS*NVW CQGKGAITAVRPSEESCRLPTSGLQGCRSNWGWA SLPTYKAAFQEGRSGVSHGRIWGVCNVTPPAAP QGLRLGRCGVPEDSRTLSHTLPNEACSEE*ELK DGAFHPLGLCAHQSRLSLQRPCIQRSCNLLVAGE RR*KMIFLRKAILLQLFPKSCSGNGWSSYSQWR GEQVGLGIYLFRLLVGWSWGIEINQEDVSTKPA VSQLRECLGSQETWTGGVWVD*ERKVPYQGTGTG KLTSQPGAMPHFP*PQLSCLHSVKPTGDVINRA IRGISHVEPPDSVHFRPAAAGGLPRAL*ENLCG HPLVYTKTEQSPALPSLPPSSFYLHASIAGVREE LTSWSVPFSRRI*DAPPPHPFSASSQVFLFCTT PESKPTSCPSIQAGKH*CGLSMITEMGDARHVR TLSSERCPRLLASCAVVLWVCHTLPCFCSHWEAH SWLTSPSQGPTWEPGSLDCPGHRFQGPPLLSSE PRGILLLKNTYGIPICAGQCPKHLDYIREEHRP HPCPHAAYVFWRKVETQVLGFRAPPAGGCAVRSG REGKCTAACEPYQPRRMPLPLSTTLASCIPSPH VPPTFKE*RAPWAQPLPWEPGSLPDLRG*GRLL GQG*LW*HCPFPLRPAQVTRASDPGLSL*EGQN* EGLFLEKENKELARLHVADTRLRILSPHWPHTT RANAQNKEFQFGAK*GRTQTLPWDLLC*RPMTN PVIGHQPPLQWGPH*QP*LHTPPGDPRGSVAVCM STLESG*TGWQDQDCGWGGQGREAGGCCEGSWS FPVAHLPLASCL*RNLVPARPSFLV*YTNVFAF FGNRENQ*IASVSL