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Sequences

Sequence NM_194323

CCGTGAGTTCTGCCCAGGCCCTGTGAGCTCACCAGAGCCACAGACTCACAGCCCAGAGGTGGCTTCTTCCTTCAGGAACTGAAGAACCCCCATGAACACC
AACATCTCCAGGTTCTGAGAACAGAACCTGGGAAATTGATGACTTCCTCATGATGACCGATACTCAGGATGGCCCTAGCGAGAGCTCCCAGATCATGAGG
AAGAAGGCCTGAACGACATACAGGAGATGATCAAAACGGAGAAGTCCTACCCTGAGCGTCGCCTGCGGGGCGTCCTGGAGGAGCTGAGCTGTGGCTGCTG
CCGCTTCCTCTCCCTCGCTGACAAGGACCAGGGCCACTCATCCCGCACCAGGCTTGACCGGGAGCGCCTCAAGTCCTGCATGAGGGAGCTGGAAAACATG
GGGCAGCAGGCCAGGATGCTGCGGGCCCAGGTGAAGCGGCACACGGTGCGGGACAAGCTGAGGCTGTGCCAGAACTTCCTGCAGAAGCTGCGCTTCCTGG
CGGACGAGCCCCAGCACAGCATTCCCGACATCTTCATCTGGATGATGAGCAACAACAAGCGTGTCGCCTATGCCCGTGTGCCCTCCAAGGACCTGCTCTT
CTCCATCGTGGAGGAGGAGACTGGCAAGGACTGCGCCAAGGTCAAGACGCTCTTCCTTAAGCTGCCAGGGAAGCGGGGCTTCGGCTCGGCAGGCTGGACA
GTGCAGGCCAAGGTGGAGCTGTACCTGTGGCTGGGCCTCAGCAAACAGCGCAAGGAGTTCCTGTGCGGCCTGCCCTGTGGCTTCCAGGAGGTCAAGGCAG
CCCAGGGCCTGGGCCTGCATGCCTTCCCACCCGTCAGCCTGGTCTACACCAAGAAGCAGGCGTTCCAGCTCCGAGCGCACATGTACCAGGCCCGCAGCCT
CTTTGCCGCCGACAGCAGCGGACTCTCAGACCCCTTTGCCCGCGTCTTCTTCATCAATCAGAGTCAGTGCACAGAGGTGCTGAATGAGACCCTGTGTCCC
ACCTGGGACCAGATGCTGGTGTTCGACAACCTGGAGCTCTATGGTGAAGCTCATGAGCTGAGGGACGATCCGCCCATCATTGTCATTGAAATCTATGACC
AGGATTCCATGGGCAAAGCTGACTTCATGGGCCGGACCTTCGCCAAACCCCTGGTGAAGATGGCAGACGAGGCGTACTGCCCACCCCGCTTCCCACCTCA
GCTCGAGTACTACCAGATCTACCGTGGCAACGCCACAGCTGGAGACCTGCTGGCGGCCTTCGAGCTGCTGCAGATTGGACCAGCAGGGAAGGCTGACCTG
CCCCCCATCAATGGCCCGGTGGACGTGGACCGAGGTCCCATCATGCCCGTGCCCATGGGCATCCGGCCCGTGCTCAGCAAGTACCGAGTGGAGGTGCTGT
TCTGGGGCCTACGGGACCTAAAGCGGGTGAACCTGGCCCAGGTGGACCGGCCACGGGTGGACATCGAGTGTGCAGGGAAGGGGGTGCAGTCGTCCCTGAT
CCACAATTATAAGAAGAACCCCAACTTCAACACCCTCGTCAAGTGGTTTGAAGTGGACCTCCCAGAGAACGAGCTGCTGCACCCGCCCTTGAACATCCGT
GTGGTGGACTGCCGGGCCTTCGGTCGCTACACACTGGTGGGCTCCCATGCCGTCAGCTCCCTGCGACGCTTCATCTACCGGCCCCCAGACCGCTCGGCCC
CCAGCTGGAACACCACGGGGGAGGTTGTGGTGACTATGGAGCCAGAGGTACCCATCAAGAAACTGGAGACCATGGTGAAGCTGGACGCGACTTCTGAAGC
TGTTGTCAAGGTGGATGTGGCTGAGGAGGAGAAGGAGAAGAAGAAGAAGAAGAAGGGCACTGCGGAGGAGCCAGAGGAGGAGGAGCCAGACGAGAGCATG
CTGGACTGGTGGTCCAAGTACTTTGCCTCCATTGACACCATGAAGGAGCAACTTCGACAACAAGAGCCCTCTGGAATTGACTTGGAGGAGAAGGAGGAAG
TGGACAATACCGAGGGCCTGAAGGGGTCAATGAAGGGCAAGGAGAAGGCAAGGGCTGCCAAAGAGGAGAAGAAGAAGAAAACTCAGAGCTCTGGCTCTGG
CCAGGGGTCCGAGGCCCCCGAGAAGAAGAAACCCAAGATTGATGAGCTTAAGGTATACCCCAAAGAGCTGGAGTCCGAGTTTGATAACTTTGAGGACTGG
CTGCACACTTTCAACTTGCTTCGGGGCAAGACCGGGGATGATGAGGATGGCTCCACCGAGGAGGAGCGCATTGTGGGACGCTTCAAGGGCTCCCTCTGCG
TGTACAAAGTGCCACTCCCAGAGGACGTGTCCCGGGAAGCCGGCTACGACTCCACCTACGGCATGTTCCAGGGCATCCCGAGCAATGACCCCATCAATGT
GCTGGTCCGAGTCTATGTGGTCCGGGCCACGGACCTGCACCCTGCTGACATCAACGGCAAAGCTGACCCCTACATCGCCATCCGGCTAGGCAAGACTGAC
ATCCGCGACAAGGAGAACTACATCTCCAAGCAGCTCAACCCTGTCTTTGGGAAGTCCTTTGACATCGAGGCCTCCTTCCCCATGGAATCCATGCTGACGG
TGGCTGTGTATGACTGGGACCTGGTGGGCACTGATGACCTCATTGGGGAAACCAAGATCGACCTGGAGAACCGCTTCTACAGCAAGCACCGCGCCACCTG
CGGCATCGCCCAGACCTACTCCACACATGGCTACAATATCTGGCGGGACCCCATGAAGCCCAGCCAGATCCTGACCCGCCTCTGCAAAGACGGCAAAGTG
GACGGCCCCCACTTTGGGCCCCCTGGGAGAGTGAAGGTGGCCAACCGCGTCTTCACTGGGCCCTCTGAGATTGAGGACGAGAACGGTCAGAGGAAGCCCA
CAGACGAGCATGTGGCGCTGTTGGCCCTGAGGCACTGGGAGGACATCCCCCGCGCAGGCTGCCGCCTGGTGCCAGAGCATGTGGAGACGAGGCCGCTGCT
CAACCCCGACAAGCCGGGCATCGAGCAGGGCCGCCTGGAGCTGTGGGTGGACATGTTCCCCATGGACATGCCAGCCCCTGGGACGCCTCTGGACATCTCA
CCTCGGAAGCCCAAGAAGTACGAGCTGCGGGTCATCATCTGGAACACAGATGAGGTGGTCTTGGAGGACGACGACTTCTTCACAGGGGAGAAGTCCAGTG
ACATCTTCGTGAGGGGGTGGCTGAAGGGCCAGCAGGAGGACAAGCAGGACACAGACGTCCACTACCACTCCCTCACTGGCGAGGGCAACTTCAACTGGCG
CTACCTGTTCCCCTTCGACTACCTGGCGGCGGAGGAGAAGATCGTCATCTCCAAGAAGGAGTCCATGTTCTCCTGGGACGAGACCGAGTACAAGATCCCC
GCGCGGCTCACCCTGCAGATCTGGGATGCGGACCACTTCTCCGCTGACGACTTCCTGGGGGCCATCGAGCTGGACCTGAACCGGTTCCCGCGGGGCGCAA
AGACAGCCAAGCAGTGCACCATGGAGATGGCCACCGGGGAGGTGGACGTGCCCCTCGTGTCCATCTTCAAGCAAAAGCGCGTCAAAGGCTGGTGGCCCCT
CCTGGCCCGCAATGAGAACGATGAGTTTGAGCTCACGGGCAAGGTGGAGGCTGAGCTGCATTTACTGACAGCAGAGGAGGCAGAGAAGAACCCAGTGGGC
CTGGCCCGCAATGAACCTGACCCCCTAGAGAAACCCAACCGGCCCGACACGGCCTTCGTCTGGTTCCTCAACCCTCTCAAGTCCATCAAGTACCTCATCT
GCACCCGGTACAAGTGGCTCATCATCAAGATCGTGCTGGCGCTGTTGGGGCTGCTCATGTTGGGGCTCTTCCTCTACAGCCTCCCTGGCTACATGGTCAA
AAAGCTCCTTGGGGCATGAAGGCCGCCAGCTCCCGCCAGCCGCTCCCCAGCCCTGCCGCATTTCCTTTCAGTGGCTTGGACTCTTTCCCATCTCCCCTGG
GGAGCCTGAGGAGCCCAGCGTCCACTCTTCATGCCTTGGGCCGAGCCTGCCTCCTGCTTGCGGGGGCCGCCTGTCCTCACTGCCCCAGGCTGCGGCTTGC
CCAGTCCCGCCCCTCTGACCCCTGCCTGTGGGCTGGGGAGCCTTGGATGGGGTGGGGACCTGGAATGGGTCTCTCTTGCCCCACCTGGCTGAGGCGCCAC
CCTTCTTCAGGCCCAGGCTCCAGAGGAAGACTCCTGAAACCCTCCCCAGGTCTTCCAAGTACAGGATTGAAGCTTTAGTGAAATTAACCAAGGACCATGG
GTCAGTGCCCAGGGCTTTAAAAAGAATGAACGAGCAAAAGGTATCCCCGCCGTGACCCCTGCAGATAGCACCGGTCTTTGATCCGCAGCAGGGGCCAGAC
CCTGCCCACAAGTCCCAGCGCGGCTGCTTCTGCCACTGCTGGGCTCCACTTGGCTCCTCTCACTTCCCAGGGGGTCGCCTGTCCTGCCTGTGGGTTTCCA
TGGCTTCCCAGAGCTCCCTCTGCCCCAGCCAGCGCCTCCAGGCCCAGCTGAGGAGCTGTGAGAAGCAGCAGAGGGGACTCCCCATCCCGGGCACACCCTG
TCCTCCCACCCCTGCCCCCTTGCCCTTCCAGCCCTTTCAGCTGCAGCTGGGAGCTGGCCCGTCAAGTGCTGCCCCTGCCTGTGTCTGGGTTTCTGTTGGC
TGTTTTTCTTTTCTTGAGTGGTGATTTTTCTCTAAATAAAAGAAGTCAAGCACTGA
  • refseq_OTOF.F3 (forward primer)
  • refseq_OTOF.R3 (reverse primer)
  • Alternative acceptor

Frame 0

P*VLPRPCELTRATDSQPRGGFFLQELKNPHEH
QHLQVLRTEPGKLMTSS**PILRMALARAPRS*G
RRPERHTGDDQNGEVLP*ASPAGRPGGAELWLL
PLPLPR*QGPGPLIPHQA*PGAPQVLHEGAGKH
GAAGQDAAGPGEAAHGAGQAEAVPELPAEAALPG
GRAPAQHSRHLHLDDEQQQACRLCPCALQGPAL
LHRGGGDWQGLRQGQDALP*AAREAGLRLGRLD
SAGQGGAVPVAGPQQTAQGVPVRPALWLPGGQGS
PGPGPACLPTRQPGLHQEAGVPAPSAHVPGPQP
LCRRQQRTLRPLCPRLLHQSESVHRGAE*DPVS
HLGPDAGVRQPGALW*SS*AEGRSAHHCH*NL*P
GFHGQS*LHGPDLRQTPGEDGRRGVLPTPLPTS
ARVLPDLPWQRHSWRPAGGLRAAADWTSREG*P
APHQWPGGRGPRSHHARAHGHPARAQQVPSGGAV
LGPTGPKAGEPGPGGPATGGHRVCREGGAVVPD
PQL*EEPQLQHPRQVV*SGPPRERAAAPALEHP
CGGLPGLRSLHTGGLPCRQLPATLHLPAPRPLGP
QLEHHGGGCGDYGARGTHQETGDHGEAGRDF*S
CCQGGCG*GGEGEEEEEEGHCGGARGGGARREH
AGLVVQVLCLH*HHEGATSTTRALWN*LGGEGGS
GQYRGPEGVNEGQGEGKGCQRGEEEENSELWLW
PGVRGPREEETQD**A*GIPQRAGVRV**L*GL
AAHFQLASGQDRG**GWLHRGGAHCGTLQGLPLR
VQSATPRGRVPGSRLRLHLRHVPGHPEQ*PHQC
AGPSLCGPGHGPAPC*HQRQS*PLHRHPARQD*
HPRQGELHLQAAQPCLWEVL*HRGLLPHGIHADG
GCV*LGPGGH**PHWGNQDRPGEPLLQQAPRHL
RHRPDLLHTWLQYLAGPHEAQPDPDPPLQRRQS
GRPPLWAPWESEGGQPRLHWAL*D*GRERSEEAH
RRACGAVGPEALGGHPPRRLPPGARACGDEAAA
QPRQAGHRAGPPGAVGGHVPHGHASPWDASGHL
TSEAQEVRAAGHHLEHR*GGLGGRRLLHRGEVQ*
HLREGVAEGPAGGQAGHRRPLPLPHWRGQLQLA
LPVPLRLPGGGGEDRHLQEGVHVLLGRDRVQDP
RAAHPADLGCGPLLR*RLPGGHRAGPEPVPAGRK
DSQAVHHGDGHRGGGRAPRVHLQAKARQRLVAP
PGPQ*ER*V*AHGQGGG*AAFTDSRGGREEPSG
PGPQ*T*PPRETQPARHGLRLVPQPSQVHQVPHL
HPVQVAHHQDRAGAVGAAHVGALPLQPPWLHGQ
KAPWGMKAASSRQPLPSPAAFPFSGLDSFPSPL
GSLRSPASTLHALGRACLLLAGAACPHCPRLRLA
QSRPSDPCLWAGEPWMGWGPGMGLSCPTWLRRH
PSSGPGSRGRLLKPSPGLPSTGLKL**N*PRTM
GQCPGL*KE*TSKRYPRRDPCR*HRSLIRSRGQT
LPTSPSAAASATAGLHLAPLTSQGVACPACGFP
WLPRAPSAPASASRPS*GAVRSSRGDSPSRAHP
VLPPLPPCPSSPFSCSWELARQVLPLPVSGFLLA
VFLFLSGDFSLNKRSQAL

Frame 1

REFCPGPVSSPEPQTHSPEVASSFRN*RTPMNT
NISRF*EQNLGN**LPHDDRYSGWP*RELPDHE
EEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCC
RFLSLADKDQGHSSRTRLDRERLKSCMRELENM
GQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFL
ADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLF
SIVEEETGKDCAKVKTLFLKLPGKRGFGSAGWT
VQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKA
AQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSL
FAADSSGLSDPFARVFFINQSQCTEVLNETLCP
TWDQMLVFDNLELYGEAHELRDDPPIIVIEIYD
QDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQ
LEYYQIYRGNATAGDLLAAFELLQIGPAGKADL
PPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVL
FWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLI
HNYKKNPNFNTLVKWFEVDLPENELLHPPLNIR
VVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSA
PSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEA
VVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESM
LDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEE
VDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSG
QGSEAPEKKKPKIDELKVYPKELESEFDNFEDW
LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC
VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINV
LVRVYVVRATDLHPADINGKADPYIAIRLGKTD
IRDKENYISKQLNPVFGKSFDIEASFPMESMLT
VAVYDWDLVGTDDLIGETKIDLENRFYSKHRATC
GIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKV
DGPHFGPPGRVKVANRVFTGPSEIEDENGQRKP
TDEHVALLALRHWEDIPRAGCRLVPEHVETRPLL
NPDKPGIEQGRLELWVDMFPMDMPAPGTPLDIS
PRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSS
DIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWR
YLFPFDYLAAEEKIVISKKESMFSWDETEYKIP
ARLTLQIWDADHFSADDFLGAIELDLNRFPRGA
KTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPL
LARNENDEFELTGKVEAELHLLTAEEAEKNPVG
LARNEPDPLEKPNRPDTAFVWFLNPLKSIKYLI
CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVK
KLLGA*RPPAPASRSPALPHFLSVAWTLSHLPW
GA*GAQRPLFMPWAEPASCLRGPPVLTAPGCGL
PSPAPLTPACGLGSLGWGGDLEWVSLAPPG*GAT
LLQAQAPEEDS*NPPQVFQVQD*SFSEINQGPW
VSAQGFKKNERAKGIPAVTPADSTGL*SAAGAR
PCPQVPARLLLPLLGSTWLLSLPRGSPVLPVGFH
GFPELPLPQPAPPGPAEEL*EAAEGTPHPGHTL
SSHPCPLALPALSAAAGSWPVKCCPCLCLGFCW
LFFFS*VVIFL*IKEVKH*

Frame 2

VSSAQAL*AHQSHRLTAQRWLLPSGTEEPP*TP
TSPGSENRTWEIDDFLMMTDTQDGPSESSQIMR
KKA*TTYRR*SKRRSPTLSVACGASWRS*AVAA
AASSPSLTRTRATHPAPGLTGSASSPA*GSWKTW
GSRPGCCGPR*SGTRCGTS*GCARTSCRSCASW
RTSPSTAFPTSSSG**ATTSVSPMPVCPPRTCS
SPSWRRRLARTAPRSRRSSLSCQGSGASARQAGQ
CRPRWSCTCGWASANSARSSCAACPVASRRSRQ
PRAWACMPSHPSAWSTPRSRRSSSERTCTRPAA
SLPPTAADSQTPLPASSSSIRVSAQRC*MRPCVP
PGTRCWCSTTWSSMVKLMS*GTIRPSLSLKSMT
RIPWAKLTSWAGPSPNPW*RWQTRRTAHPASHL
SSSTTRSTVATPQLETCWRPSSCCRLDQQGRLTC
PPSMARWTWTEVPSCPCPWASGPCSASTEWRCC
SGAYGT*SG*TWPRWTGHGWTSSVQGRGCSRP*
STIIRRTPTSTPSSSGLKWTSQRTSCCTRP*TSV
WWTAGPSVATHWWAPMPSAPCDASSTGPQTARP
PAGTPRGRLW*LWSQRYPSRNWRPW*SWTRLLK
LLSRWMWLRRRRRRRRRRRALRRSQRRRSQTRAC
WTGGPSTLPPLTP*RSNFDNKSPLELTWRRRRK
WTIPRA*RGQ*RARRRQGLPKRRRRRKLRALAL
ARGPRPPRRRNPRLMSLRYTPKSWSPSLITLRTG
CTLSTCFGARPGMMRMAPPRRSALWDASRAPSA
CTKCHSQRTCPGKPATTPPTACSRASRAMTPSM
CWSESMWSGPRTCTLLTSTAKLTPTSPSG*ARLT
SATRRTTSPSSSTLSLGSPLTSRPPSPWNPC*R
WLCMTGTWWALMTSLGKPRSTWRTASTASTAPP
AASPRPTPHMATISGGTP*SPARS*PASAKTAKW
TAPTLGPLGE*RWPTASSLGPLRLRTRTVRGSP
QTSMWRCWP*GTGRTSPAQAAAWCQSMWRRGRC
STPTSRASSRAAWSCGWTCSPWTCQPLGRLWTSH
LGSPRSTSCGSSSGTQMRWSWRTTTSSQGRSPV
TSS*GGG*RASRRTSRTQTSTTTPSLARATSTG
ATCSPSTTWRRRRRSSSPRRSPCSPGTRPSTRSP
RGSPCRSGMRTTSPLTTSWGPSSWT*TGSRGAQ
RQPSSAPWRWPPGRWTCPSCPSSSKSASKAGGP
SWPAMRTMSLSSRARWRLSCIY*QQRRQRRTQWA
WPAMNLTP*RNPTGPTRPSSGSSTLSSPSSTSS
APGTSGSSSRSCWRCWGCSCWGSSSTASLATWS
KSSLGHEGRQLPPAAPQPCRISFQWLGLFPISPG
EPEEPSVHSSCLGPSLPPACGGRLSSLPQAAAC
PVPPL*PLPVGWGALDGVGTWNGSLLPHLAEAP
PFFRPRLQRKTPETLPRSSKYRIEALVKLTKDHG
SVPRALKRMNEQKVSPP*PLQIAPVFDPQQGPD
PAHKSQRGCFCHCWAPLGSSHFPGGRLSCLWVS
MASQSSLCPSQRLQAQLRSCEKQQRGLPIPGTPC
PPTPAPLPFQPFQLQLGAGPSSAAPACVWVSVG
CFSFLEW*FFSK*KKSST

Sequence NM_004802

CCGTGAGTTCTGCCCAGGCCCTGTGAGCTCACCAGAGCCACAGACTCACAGCCCAGAGGTGGCTTCTTCCTTCAGGAACTGAAGAACCCCCATGAACACC
AACATCTCCAGGTTCTGAGAACAGAACCTGGGAAATTGATGACTTCCTCATGATGACCGATACTCAGGATGGCCCTAGCGAGAGCTCCCAGATCATGAGG
AAGAAGGCCTGAACGACATACAGGAGATGATCAAAACGGAGAAGTCCTACCCTGAGCGTCGCCTGCGGGGCGTCCTGGAGGAGCTGAGCTGTGGCTGCTG
CCGCTTCCTCTCCCTCGCTGACAAGGACCAGGGCCACTCATCCCGCACCAGGCTTGACCGGGAGCGCCTCAAGTCCTGCATGAGGGAGCTGGAAAACATG
GGGCAGCAGGCCAGGATGCTGCGGGCCCAGGTGAAGCGGCACACGGTGCGGGACAAGCTGAGGCTGTGCCAGAACTTCCTGCAGAAGCTGCGCTTCCTGG
CGGACGAGCCCCAGCACAGCATTCCCGACATCTTCATCTGGATGATGAGCAACAACAAGCGTGTCGCCTATGCCCGTGTGCCCTCCAAGGACCTGCTCTT
CTCCATCGTGGAGGAGGAGACTGGCAAGGACTGCGCCAAGGTCAAGACGCTCTTCCTTAAGCTGCCAGGGAAGCGGGGCTTCGGCTCGGCAGGCTGGACA
GTGCAGGCCAAGGTGGAGCTGTACCTGTGGCTGGGCCTCAGCAAACAGCGCAAGGAGTTCCTGTGCGGCCTGCCCTGTGGCTTCCAGGAGGTCAAGGCAG
CCCAGGGCCTGGGCCTGCATGCCTTCCCACCCGTCAGCCTGGTCTACACCAAGAAGCAGGCGTTCCAGCTCCGAGCGCACATGTACCAGGCCCGCAGCCT
CTTTGCCGCCGACAGCAGCGGACTCTCAGACCCCTTTGCCCGCGTCTTCTTCATCAATCAGAGTCAGTGCACAGAGGTGCTGAATGAGACCCTGTGTCCC
ACCTGGGACCAGATGCTGGTGTTCGACAACCTGGAGCTCTATGGTGAAGCTCATGAGCTGAGGGACGATCCGCCCATCATTGTCATTGAAATCTATGACC
AGGATTCCATGGGCAAAGCTGACTTCATGGGCCGGACCTTCGCCAAACCCCTGGTGAAGATGGCAGACGAGGCGTACTGCCCACCCCGCTTCCCACCTCA
GCTCGAGTACTACCAGATCTACCGTGGCAACGCCACAGCTGGAGACCTGCTGGCGGCCTTCGAGCTGCTGCAGATTGGACCAGCAGGGAAGGCTGACCTG
CCCCCCATCAATGGCCCGGTGGACGTGGACCGAGGTCCCATCATGCCCGTGCCCATGGGCATCCGGCCCGTGCTCAGCAAGTACCGAGTGGAGGTGCTGT
TCTGGGGCCTACGGGACCTAAAGCGGGTGAACCTGGCCCAGGTGGACCGGCCACGGGTGGACATCGAGTGTGCAGGGAAGGGGGTGCAGTCGTCCCTGAT
CCACAATTATAAGAAGAACCCCAACTTCAACACCCTCGTCAAGTGGTTTGAAGTGGACCTCCCAGAGAACGAGCTGCTGCACCCGCCCTTGAACATCCGT
GTGGTGGACTGCCGGGCCTTCGGTCGCTACACACTGGTGGGCTCCCATGCCGTCAGCTCCCTGCGACGCTTCATCTACCGGCCCCCAGACCGCTCGGCCC
CCAGCTGGAACACCACGGGGGAGGTTGTGGTGACTATGGAGCCAGAGGTACCCATCAAGAAACTGGAGACCATGGTGAAGCTGGACGCGACTTCTGAAGC
TGTTGTCAAGGTGGATGTGGCTGAGGAGGAGAAGGAGAAGAAGAAGAAGAAGAAGGGCACTGCGGAGGAGCCAGAGGAGGAGGAGCCAGACGAGAGCATG
CTGGACTGGTGGTCCAAGTACTTTGCCTCCATTGACACCATGAAGGAGCAACTTCGACAACAAGAGCCCTCTGGAATTGACTTGGAGGAGAAGGAGGAAG
TGGACAATACCGAGGGCCTGAAGGGGTCAATGAAGGGCAAGGAGAAGGCAAGGGCTGCCAAAGAGGAGAAGAAGAAGAAAACTCAGAGCTCTGGCTCTGG
CCAGGGGTCCGAGGCCCCCGAGAAGAAGAAACCCAAGATTGATGAGCTTAAGGTATACCCCAAAGAGCTGGAGTCCGAGTTTGATAACTTTGAGGACTGG
CTGCACACTTTCAACTTGCTTCGGGGCAAGACCGGGGATGATGAGGATGGCTCCACCGAGGAGGAGCGCATTGTGGGACGCTTCAAGGGCTCCCTCTGCG
TGTACAAAGTGCCACTCCCAGAGGACGTGTCCCGGGAAGCCGGCTACGACTCCACCTACGGCATGTTCCAGGGCATCCCGAGCAATGACCCCATCAATGT
GCTGGTCCGAGTCTATGTGGTCCGGGCCACGGACCTGCACCCTGCTGACATCAACGGCAAAGCTGACCCCTACATCGCCATCCGGCTAGGCAAGACTGAC
ATCCGCGACAAGGAGAACTACATCTCCAAGCAGCTCAACCCTGTCTTTGGGAAGTCCTTTGACATCGAGGCCTCCTTCCCCATGGAATCCATGCTGACGG
TGGCTGTGTATGACTGGGACCTGGTGGGCACTGATGACCTCATTGGGGAAACCAAGATCGACCTGGAGAACCGCTTCTACAGCAAGCACCGCGCCACCTG
CGGCATCGCCCAGACCTACTCCACACATGGCTACAATATCTGGCGGGACCCCATGAAGCCCAGCCAGATCCTGACCCGCCTCTGCAAAGACGGCAAAGTG
GACGGCCCCCACTTTGGGCCCCCTGGGAGAGTGAAGGTGGCCAACCGCGTCTTCACTGGGCCCTCTGAGATTGAGGACGAGAACGGTCAGAGGAAGCCCA
CAGACGAGCATGTGGCGCTGTTGGCCCTGAGGCACTGGGAGGACATCCCCCGCGCAGGCTGCCGCCTGGTGCCAGAGCATGTGGAGACGAGGCCGCTGCT
CAACCCCGACAAGCCGGGCATCGAGCAGGGCCGCCTGGAGCTGTGGGTGGACATGTTCCCCATGGACATGCCAGCCCCTGGGACGCCTCTGGACATCTCA
CCTCGGAAGCCCAAGAAGTACGAGCTGCGGGTCATCATCTGGAACACAGATGAGGTGGTCTTGGAGGACGACGACTTCTTCACAGGGGAGAAGTCCAGTG
ACATCTTCGTGAGGGGGTGGCTGAAGGGCCAGCAGGAGGACAAGCAGGACACAGACGTCCACTACCACTCCCTCACTGGCGAGGGCAACTTCAACTGGCG
CTACCTGTTCCCCTTCGACTACCTGGCGGCGGAGGAGAAGATCGTCATCTCCAAGAAGGAGTCCATGTTCTCCTGGGACGAGACCGAGTACAAGATCCCC
GCGCGGCTCACCCTGCAGATCTGGGATGCGGACCACTTCTCCGCTGACGACTTCCTGGGGGCCATCGAGCTGGACCTGAACCGGTTCCCGCGGGGCGCAA
AGACAGCCAAGCAGTGCACCATGGAGATGGCCACCGGGGAGGTGGACGTGCCCCTCGTGTCCATCTTCAAGCAAAAGCGCGTCAAAGGCTGGTGGCCCCT
CCTGGCCCGCAATGAGAACGATGAGTTTGAGCTCACGGGCAAGGTGGAGGCTGAGCTGCATTTACTGACAGCAGAGGAGGCAGAGAAGAACCCAGTGGGC
CTGGCCCGCAATGAACCTGACCCCCTAGAGAAACCCAACCGGCCCGACACGAGCTTCATCTGGTTCCTGAACCCTCTCAAGTCGGCTCGCTACTTCTTGT
GGCACACGTATCGCTGGCTGCTCCTCAAACTGTTGCTGCTCCTGCTGCTGCTCCTCCTCCTCGCCCTGTTCCTCTACTCTGTGCCTGGCTACCTGGTCAA
GAAAATCCTCGGGGCCTGAGCCCAGTGGCCTCCTGGCCGGCCCGACACGGCCTTCGTCTGGTTCCTCAACCCTCTCAAGTCCATCAAGTACCTCATCTGC
ACCCGGTACAAGTGGCTCATCATCAAGATCGTGCTGGCGCTGTTGGGGCTGCTCATGTTGGGGCTCTTCCTCTACAGCCTCCCTGGCTACATGGTCAAAA
AGCTCCTTGGGGCATGAAGGCCGCCAGCTCCCGCCAGCCGCTCCCCAGCCCTGCCGCATTTCCTTTCAGTGGCTTGGACTCTTTCCCATCTCCCCTGGGG
AGCCTGAGGAGCCCAGCGTCCACTCTTCATGCCTTGGGCCGAGCCTGCCTCCTGCTTGCGGGGGCCGCCTGTCCTCACTGCCCCAGGCTGCGGCTTGCCC
AGTCCCGCCCCTCTGACCCCTGCCTGTGGGCTGGGGAGCCTTGGATGGGGTGGGGACCTGGAATGGGTCTCTCTTGCCCCACCTGGCTGAGGCGCCACCC
TTCTTCAGGCCCAGGCTCCAGAGGAAGACTCCTGAAACCCTCCCCAGGTCTTCCAAGTACAGGATTGAAGCTTTAGTGAAATTAACCAAGGACCATGGGT
CAGTGCCCAGGGCTTTAAAAAGAATGAACGAGCAAAAGGTATCCCCGCCGTGACCCCTGCAGATAGCACCGGTCTTTGATCCGCAGCAGGGGCCAGACCC
TGCCCACAAGTCCCAGCGCGGCTGCTTCTGCCACTGCTGGGCTCCACTTGGCTCCTCTCACTTCCCAGGGGGTCGCCTGTCCTGCCTGTGGGTTTCCATG
GCTTCCCAGAGCTCCCTCTGCCCCAGCCAGCGCCTCCAGGCCCAGCTGAGGAGCTGTGAGAAGCAGCAGAGGGGACTCCCCATCCCGGGCACACCCTGTC
CTCCCACCCCTGCCCCCTTGCCCTTCCAGCCCTTTCAGCTGCAGCTGGGAGCTGGCCCGTCAAGTGCTGCCCCTGCCTGTGTCTGGGTTTCTGTTGGCTG
TTTTTCTTTTCTTGAGTGGTGATTTTTCTCTAAATAAAAGAAGTCAAGCACTGA
  • refseq_OTOF.F3 (forward primer)
  • refseq_OTOF.R3 (reverse primer)
  • Alternative acceptor

Frame 0

P*VLPRPCELTRATDSQPRGGFFLQELKNPHEH
QHLQVLRTEPGKLMTSS**PILRMALARAPRS*G
RRPERHTGDDQNGEVLP*ASPAGRPGGAELWLL
PLPLPR*QGPGPLIPHQA*PGAPQVLHEGAGKH
GAAGQDAAGPGEAAHGAGQAEAVPELPAEAALPG
GRAPAQHSRHLHLDDEQQQACRLCPCALQGPAL
LHRGGGDWQGLRQGQDALP*AAREAGLRLGRLD
SAGQGGAVPVAGPQQTAQGVPVRPALWLPGGQGS
PGPGPACLPTRQPGLHQEAGVPAPSAHVPGPQP
LCRRQQRTLRPLCPRLLHQSESVHRGAE*DPVS
HLGPDAGVRQPGALW*SS*AEGRSAHHCH*NL*P
GFHGQS*LHGPDLRQTPGEDGRRGVLPTPLPTS
ARVLPDLPWQRHSWRPAGGLRAAADWTSREG*P
APHQWPGGRGPRSHHARAHGHPARAQQVPSGGAV
LGPTGPKAGEPGPGGPATGGHRVCREGGAVVPD
PQL*EEPQLQHPRQVV*SGPPRERAAAPALEHP
CGGLPGLRSLHTGGLPCRQLPATLHLPAPRPLGP
QLEHHGGGCGDYGARGTHQETGDHGEAGRDF*S
CCQGGCG*GGEGEEEEEEGHCGGARGGGARREH
AGLVVQVLCLH*HHEGATSTTRALWN*LGGEGGS
GQYRGPEGVNEGQGEGKGCQRGEEEENSELWLW
PGVRGPREEETQD**A*GIPQRAGVRV**L*GL
AAHFQLASGQDRG**GWLHRGGAHCGTLQGLPLR
VQSATPRGRVPGSRLRLHLRHVPGHPEQ*PHQC
AGPSLCGPGHGPAPC*HQRQS*PLHRHPARQD*
HPRQGELHLQAAQPCLWEVL*HRGLLPHGIHADG
GCV*LGPGGH**PHWGNQDRPGEPLLQQAPRHL
RHRPDLLHTWLQYLAGPHEAQPDPDPPLQRRQS
GRPPLWAPWESEGGQPRLHWAL*D*GRERSEEAH
RRACGAVGPEALGGHPPRRLPPGARACGDEAAA
QPRQAGHRAGPPGAVGGHVPHGHASPWDASGHL
TSEAQEVRAAGHHLEHR*GGLGGRRLLHRGEVQ*
HLREGVAEGPAGGQAGHRRPLPLPHWRGQLQLA
LPVPLRLPGGGGEDRHLQEGVHVLLGRDRVQDP
RAAHPADLGCGPLLR*RLPGGHRAGPEPVPAGRK
DSQAVHHGDGHRGGGRAPRVHLQAKARQRLVAP
PGPQ*ER*V*AHGQGGG*AAFTDSRGGREEPSG
PGPQ*T*PPRETQPARHELHLVPEPSQVGSLLLV
AHVSLAAPQTVAAPAAAPPPRPVPLLCAWLPGQ
ENPRGLSPVASWPARHGLRLVPQPSQVHQVPHL
HPVQVAHHQDRAGAVGAAHVGALPLQPPWLHGQK
APWGMKAASSRQPLPSPAAFPFSGLDSFPSPLG
SLRSPASTLHALGRACLLLAGAACPHCPRLRLA
QSRPSDPCLWAGEPWMGWGPGMGLSCPTWLRRHP
SSGPGSRGRLLKPSPGLPSTGLKL**N*PRTMG
QCPGL*KE*TSKRYPRRDPCR*HRSLIRSRGQT
LPTSPSAAASATAGLHLAPLTSQGVACPACGFPW
LPRAPSAPASASRPS*GAVRSSRGDSPSRAHPV
LPPLPPCPSSPFSCSWELARQVLPLPVSGFLLA
VFLFLSGDFSLNKRSQAL

Frame 1

REFCPGPVSSPEPQTHSPEVASSFRN*RTPMNT
NISRF*EQNLGN**LPHDDRYSGWP*RELPDHE
EEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCC
RFLSLADKDQGHSSRTRLDRERLKSCMRELENM
GQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFL
ADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLF
SIVEEETGKDCAKVKTLFLKLPGKRGFGSAGWT
VQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKA
AQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSL
FAADSSGLSDPFARVFFINQSQCTEVLNETLCP
TWDQMLVFDNLELYGEAHELRDDPPIIVIEIYD
QDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQ
LEYYQIYRGNATAGDLLAAFELLQIGPAGKADL
PPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVL
FWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLI
HNYKKNPNFNTLVKWFEVDLPENELLHPPLNIR
VVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSA
PSWNTTGEVVVTMEPEVPIKKLETMVKLDATSEA
VVKVDVAEEEKEKKKKKKGTAEEPEEEEPDESM
LDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEE
VDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSG
QGSEAPEKKKPKIDELKVYPKELESEFDNFEDW
LHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC
VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINV
LVRVYVVRATDLHPADINGKADPYIAIRLGKTD
IRDKENYISKQLNPVFGKSFDIEASFPMESMLT
VAVYDWDLVGTDDLIGETKIDLENRFYSKHRATC
GIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKV
DGPHFGPPGRVKVANRVFTGPSEIEDENGQRKP
TDEHVALLALRHWEDIPRAGCRLVPEHVETRPLL
NPDKPGIEQGRLELWVDMFPMDMPAPGTPLDIS
PRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSS
DIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWR
YLFPFDYLAAEEKIVISKKESMFSWDETEYKIP
ARLTLQIWDADHFSADDFLGAIELDLNRFPRGA
KTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPL
LARNENDEFELTGKVEAELHLLTAEEAEKNPVG
LARNEPDPLEKPNRPDTSFIWFLNPLKSARYFL
WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVK
KILGA*AQWPPGRPDTAFVWFLNPLKSIKYLIC
TRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVK
KLLGA*RPPAPASRSPALPHFLSVAWTLSHLPWG
A*GAQRPLFMPWAEPASCLRGPPVLTAPGCGLP
SPAPLTPACGLGSLGWGGDLEWVSLAPPG*GAT
LLQAQAPEEDS*NPPQVFQVQD*SFSEINQGPWV
SAQGFKKNERAKGIPAVTPADSTGL*SAAGARP
CPQVPARLLLPLLGSTWLLSLPRGSPVLPVGFH
GFPELPLPQPAPPGPAEEL*EAAEGTPHPGHTLS
SHPCPLALPALSAAAGSWPVKCCPCLCLGFCWL
FFFS*VVIFL*IKEVKH*

Frame 2

VSSAQAL*AHQSHRLTAQRWLLPSGTEEPP*TP
TSPGSENRTWEIDDFLMMTDTQDGPSESSQIMR
KKA*TTYRR*SKRRSPTLSVACGASWRS*AVAA
AASSPSLTRTRATHPAPGLTGSASSPA*GSWKTW
GSRPGCCGPR*SGTRCGTS*GCARTSCRSCASW
RTSPSTAFPTSSSG**ATTSVSPMPVCPPRTCS
SPSWRRRLARTAPRSRRSSLSCQGSGASARQAGQ
CRPRWSCTCGWASANSARSSCAACPVASRRSRQ
PRAWACMPSHPSAWSTPRSRRSSSERTCTRPAA
SLPPTAADSQTPLPASSSSIRVSAQRC*MRPCVP
PGTRCWCSTTWSSMVKLMS*GTIRPSLSLKSMT
RIPWAKLTSWAGPSPNPW*RWQTRRTAHPASHL
SSSTTRSTVATPQLETCWRPSSCCRLDQQGRLTC
PPSMARWTWTEVPSCPCPWASGPCSASTEWRCC
SGAYGT*SG*TWPRWTGHGWTSSVQGRGCSRP*
STIIRRTPTSTPSSSGLKWTSQRTSCCTRP*TSV
WWTAGPSVATHWWAPMPSAPCDASSTGPQTARP
PAGTPRGRLW*LWSQRYPSRNWRPW*SWTRLLK
LLSRWMWLRRRRRRRRRRRALRRSQRRRSQTRAC
WTGGPSTLPPLTP*RSNFDNKSPLELTWRRRRK
WTIPRA*RGQ*RARRRQGLPKRRRRRKLRALAL
ARGPRPPRRRNPRLMSLRYTPKSWSPSLITLRTG
CTLSTCFGARPGMMRMAPPRRSALWDASRAPSA
CTKCHSQRTCPGKPATTPPTACSRASRAMTPSM
CWSESMWSGPRTCTLLTSTAKLTPTSPSG*ARLT
SATRRTTSPSSSTLSLGSPLTSRPPSPWNPC*R
WLCMTGTWWALMTSLGKPRSTWRTASTASTAPP
AASPRPTPHMATISGGTP*SPARS*PASAKTAKW
TAPTLGPLGE*RWPTASSLGPLRLRTRTVRGSP
QTSMWRCWP*GTGRTSPAQAAAWCQSMWRRGRC
STPTSRASSRAAWSCGWTCSPWTCQPLGRLWTSH
LGSPRSTSCGSSSGTQMRWSWRTTTSSQGRSPV
TSS*GGG*RASRRTSRTQTSTTTPSLARATSTG
ATCSPSTTWRRRRRSSSPRRSPCSPGTRPSTRSP
RGSPCRSGMRTTSPLTTSWGPSSWT*TGSRGAQ
RQPSSAPWRWPPGRWTCPSCPSSSKSASKAGGP
SWPAMRTMSLSSRARWRLSCIY*QQRRQRRTQWA
WPAMNLTP*RNPTGPTRASSGS*TLSSRLATSC
GTRIAGCSSNCCCSCCCSSSSPCSSTLCLATWS
RKSSGPEPSGLLAGPTRPSSGSSTLSSPSSTSSA
PGTSGSSSRSCWRCWGCSCWGSSSTASLATWSK
SSLGHEGRQLPPAAPQPCRISFQWLGLFPISPG
EPEEPSVHSSCLGPSLPPACGGRLSSLPQAAACP
VPPL*PLPVGWGALDGVGTWNGSLLPHLAEAPP
FFRPRLQRKTPETLPRSSKYRIEALVKLTKDHG
SVPRALKRMNEQKVSPP*PLQIAPVFDPQQGPDP
AHKSQRGCFCHCWAPLGSSHFPGGRLSCLWVSM
ASQSSLCPSQRLQAQLRSCEKQQRGLPIPGTPC
PPTPAPLPFQPFQLQLGAGPSSAAPACVWVSVGC
FSFLEW*FFSK*KKSST

Sequence NM_194322

CCGTGAGTTCTGCCCAGGCCCTGTGAGCTCACCAGAGCCACAGACTCACAGCCCAGAGGTGGCTTCTTCCTTCAGGAACTGAAGAACCCCCATGAACACC
AACATCTCCAGGTTCTGAGAACAGAACCTGGGAAATTGATGACTTCCTCATGATGACCGATACTCAGGATGGCCCTAGCGAGAGCTCCCAGATCATGAGG
TCCCTCACTCCCCTGATCAACAGGGAGGAGGCATTTGGGGAGGCTGGGGAGGCGGGGCTGTGGCCCAGCATCACCCACACTCCTGATTCACAGGAAGAAG
GCCTGAACGACATACAGGAGATGATCAAAACGGAGAAGTCCTACCCTGAGCGTCGCCTGCGGGGCGTCCTGGAGGAGCTGAGCTGTGGCTGCTGCCGCTT
CCTCTCCCTCGCTGACAAGGACCAGGGCCACTCATCCCGCACCAGGCTTGACCGGGAGCGCCTCAAGTCCTGCATGAGGGAGCTGGAAAACATGGGGCAG
CAGGCCAGGATGCTGCGGGCCCAGGTGAAGCGGCACACGGTGCGGGACAAGCTGAGGCTGTGCCAGAACTTCCTGCAGAAGCTGCGCTTCCTGGCGGACG
AGCCCCAGCACAGCATTCCCGACATCTTCATCTGGATGATGAGCAACAACAAGCGTGTCGCCTATGCCCGTGTGCCCTCCAAGGACCTGCTCTTCTCCAT
CGTGGAGGAGGAGACTGGCAAGGACTGCGCCAAGGTCAAGACGCTCTTCCTTAAGCTGCCAGGGAAGCGGGGCTTCGGCTCGGCAGGCTGGACAGTGCAG
GCCAAGGTGGAGCTGTACCTGTGGCTGGGCCTCAGCAAACAGCGCAAGGAGTTCCTGTGCGGCCTGCCCTGTGGCTTCCAGGAGGTCAAGGCAGCCCAGG
GCCTGGGCCTGCATGCCTTCCCACCCGTCAGCCTGGTCTACACCAAGAAGCAGGCGTTCCAGCTCCGAGCGCACATGTACCAGGCCCGCAGCCTCTTTGC
CGCCGACAGCAGCGGACTCTCAGACCCCTTTGCCCGCGTCTTCTTCATCAATCAGAGTCAGTGCACAGAGGTGCTGAATGAGACCCTGTGTCCCACCTGG
GACCAGATGCTGGTGTTCGACAACCTGGAGCTCTATGGTGAAGCTCATGAGCTGAGGGACGATCCGCCCATCATTGTCATTGAAATCTATGACCAGGATT
CCATGGGCAAAGCTGACTTCATGGGCCGGACCTTCGCCAAACCCCTGGTGAAGATGGCAGACGAGGCGTACTGCCCACCCCGCTTCCCACCTCAGCTCGA
GTACTACCAGATCTACCGTGGCAACGCCACAGCTGGAGACCTGCTGGCGGCCTTCGAGCTGCTGCAGATTGGACCAGCAGGGAAGGCTGACCTGCCCCCC
ATCAATGGCCCGGTGGACGTGGACCGAGGTCCCATCATGCCCGTGCCCATGGGCATCCGGCCCGTGCTCAGCAAGTACCGAGTGGAGGTGCTGTTCTGGG
GCCTACGGGACCTAAAGCGGGTGAACCTGGCCCAGGTGGACCGGCCACGGGTGGACATCGAGTGTGCAGGGAAGGGGGTGCAGTCGTCCCTGATCCACAA
TTATAAGAAGAACCCCAACTTCAACACCCTCGTCAAGTGGTTTGAAGTGGACCTCCCAGAGAACGAGCTGCTGCACCCGCCCTTGAACATCCGTGTGGTG
GACTGCCGGGCCTTCGGTCGCTACACACTGGTGGGCTCCCATGCCGTCAGCTCCCTGCGACGCTTCATCTACCGGCCCCCAGACCGCTCGGCCCCCAGCT
GGAACACCACGGTCAGGCTTCTCCGGCGCTGCCGTGTGCTGTGCAATGGGGGCTCCTCCTCTCACTCCACAGGGGAGGTTGTGGTGACTATGGAGCCAGA
GGTACC
CATCAAGAAACTGGAGACCATGGTGAAGCTGGACGCGACTTCTGAAGCTGTTGTCAAGGTGGATGTGGCTGAGGAGGAGAAGGAGAAGAAGAAG
AAGAAGAAGGGCACTGCGGAGGAGCCAGAGGAGGAGGAGCCAGACGAGAGCATGCTGGACTGGTGGTCCAAGTACTTTGCCTCCATTGACACCATGAAGG
AGCAACTTCGACAACAAGAGCCCTCTGGAATTGACTTGGAGGAGAAGGAGGAAGTGGACAATACCGAGGGCCTGAAGGGGTCAATGAAGGGCAAGGAGAA
GGCAAGGGCTGCCAAAGAGGAGAAGAAGAAGAAAACTCAGAGCTCTGGCTCTGGCCAGGGGTCCGAGGCCCCCGAGAAGAAGAAACCCAAGATTGATGAG
CTTAAGGTATACCCCAAAGAGCTGGAGTCCGAGTTTGATAACTTTGAGGACTGGCTGCACACTTTCAACTTGCTTCGGGGCAAGACCGGGGATGATGAGG
ATGGCTCCACCGAGGAGGAGCGCATTGTGGGACGCTTCAAGGGCTCCCTCTGCGTGTACAAAGTGCCACTCCCAGAGGACGTGTCCCGGGAAGCCGGCTA
CGACTCCACCTACGGCATGTTCCAGGGCATCCCGAGCAATGACCCCATCAATGTGCTGGTCCGAGTCTATGTGGTCCGGGCCACGGACCTGCACCCTGCT
GACATCAACGGCAAAGCTGACCCCTACATCGCCATCCGGCTAGGCAAGACTGACATCCGCGACAAGGAGAACTACATCTCCAAGCAGCTCAACCCTGTCT
TTGGGAAGTCCTTTGACATCGAGGCCTCCTTCCCCATGGAATCCATGCTGACGGTGGCTGTGTATGACTGGGACCTGGTGGGCACTGATGACCTCATTGG
GGAAACCAAGATCGACCTGGAGAACCGCTTCTACAGCAAGCACCGCGCCACCTGCGGCATCGCCCAGACCTACTCCACACATGGCTACAATATCTGGCGG
GACCCCATGAAGCCCAGCCAGATCCTGACCCGCCTCTGCAAAGACGGCAAAGTGGACGGCCCCCACTTTGGGCCCCCTGGGAGAGTGAAGGTGGCCAACC
GCGTCTTCACTGGGCCCTCTGAGATTGAGGACGAGAACGGTCAGAGGAAGCCCACAGACGAGCATGTGGCGCTGTTGGCCCTGAGGCACTGGGAGGACAT
CCCCCGCGCAGGCTGCCGCCTGGTGCCAGAGCATGTGGAGACGAGGCCGCTGCTCAACCCCGACAAGCCGGGCATCGAGCAGGGCCGCCTGGAGCTGTGG
GTGGACATGTTCCCCATGGACATGCCAGCCCCTGGGACGCCTCTGGACATCTCACCTCGGAAGCCCAAGAAGTACGAGCTGCGGGTCATCATCTGGAACA
CAGATGAGGTGGTCTTGGAGGACGACGACTTCTTCACAGGGGAGAAGTCCAGTGACATCTTCGTGAGGGGGTGGCTGAAGGGCCAGCAGGAGGACAAGCA
GGACACAGACGTCCACTACCACTCCCTCACTGGCGAGGGCAACTTCAACTGGCGCTACCTGTTCCCCTTCGACTACCTGGCGGCGGAGGAGAAGATCGTC
ATCTCCAAGAAGGAGTCCATGTTCTCCTGGGACGAGACCGAGTACAAGATCCCCGCGCGGCTCACCCTGCAGATCTGGGATGCGGACCACTTCTCCGCTG
ACGACTTCCTGGGGGCCATCGAGCTGGACCTGAACCGGTTCCCGCGGGGCGCAAAGACAGCCAAGCAGTGCACCATGGAGATGGCCACCGGGGAGGTGGA
CGTGCCCCTCGTGTCCATCTTCAAGCAAAAGCGCGTCAAAGGCTGGTGGCCCCTCCTGGCCCGCAATGAGAACGATGAGTTTGAGCTCACGGGCAAGGTG
GAGGCTGAGCTGCATTTACTGACAGCAGAGGAGGCAGAGAAGAACCCAGTGGGCCTGGCCCGCAATGAACCTGACCCCCTAGAGAAACCCAACCGGCCCG
ACACGAGCTTCATCTGGTTCCTGAACCCTCTCAAGTCGGCTCGCTACTTCTTGTGGCACACGTATCGCTGGCTGCTCCTCAAACTGTTGCTGCTCCTGCT
GCTGCTCCTCCTCCTCGCCCTGTTCCTCTACTCTGTGCCTGGCTACCTGGTCAAGAAAATCCTCGGGGCCTGAGCCCAGTGGCCTCCTGGCCGGCCCGAC
ACGGCCTTCGTCTGGTTCCTCAACCCTCTCAAGTCCATCAAGTACCTCATCTGCACCCGGTACAAGTGGCTCATCATCAAGATCGTGCTGGCGCTGTTGG
GGCTGCTCATGTTGGGGCTCTTCCTCTACAGCCTCCCTGGCTACATGGTCAAAAAGCTCCTTGGGGCATGAAGGCCGCCAGCTCCCGCCAGCCGCTCCCC
AGCCCTGCCGCATTTCCTTTCAGTGGCTTGGACTCTTTCCCATCTCCCCTGGGGAGCCTGAGGAGCCCAGCGTCCACTCTTCATGCCTTGGGCCGAGCCT
GCCTCCTGCTTGCGGGGGCCGCCTGTCCTCACTGCCCCAGGCTGCGGCTTGCCCAGTCCCGCCCCTCTGACCCCTGCCTGTGGGCTGGGGAGCCTTGGAT
GGGGTGGGGACCTGGAATGGGTCTCTCTTGCCCCACCTGGCTGAGGCGCCACCCTTCTTCAGGCCCAGGCTCCAGAGGAAGACTCCTGAAACCCTCCCCA
GGTCTTCCAAGTACAGGATTGAAGCTTTAGTGAAATTAACCAAGGACCATGGGTCAGTGCCCAGGGCTTTAAAAAGAATGAACGAGCAAAAGGTATCCCC
GCCGTGACCCCTGCAGATAGCACCGGTCTTTGATCCGCAGCAGGGGCCAGACCCTGCCCACAAGTCCCAGCGCGGCTGCTTCTGCCACTGCTGGGCTCCA
CTTGGCTCCTCTCACTTCCCAGGGGGTCGCCTGTCCTGCCTGTGGGTTTCCATGGCTTCCCAGAGCTCCCTCTGCCCCAGCCAGCGCCTCCAGGCCCAGC
TGAGGAGCTGTGAGAAGCAGCAGAGGGGACTCCCCATCCCGGGCACACCCTGTCCTCCCACCCCTGCCCCCTTGCCCTTCCAGCCCTTTCAGCTGCAGCT
GGGAGCTGGCCCGTCAAGTGCTGCCCCTGCCTGTGTCTGGGTTTCTGTTGGCTGTTTTTCTTTTCTTGAGTGGTGATTTTTCTCTAAATAAAAGAAGTCA
AGCACTGA
  • refseq_OTOF.F3 (forward primer)
  • refseq_OTOF.R3 (reverse primer)
  • Alternative acceptor

Frame 0

P*VLPRPCELTRATDSQPRGGFFLQELKNPHEH
QHLQVLRTEPGKLMTSS**PILRMALARAPRS*G
PSLP*STGRRHLGRLGRRGCGPASPTLLIHRKK
A*TTYRR*SKRRSPTLSVACGASWRS*AVAAAA
SSPSLTRTRATHPAPGLTGSASSPA*GSWKTWGS
RPGCCGPR*SGTRCGTS*GCARTSCRSCASWRT
SPSTAFPTSSSG**ATTSVSPMPVCPPRTCSSP
SWRRRLARTAPRSRRSSLSCQGSGASARQAGQCR
PRWSCTCGWASANSARSSCAACPVASRRSRQPR
AWACMPSHPSAWSTPRSRRSSSERTCTRPAASL
PPTAADSQTPLPASSSSIRVSAQRC*MRPCVPPG
TRCWCSTTWSSMVKLMS*GTIRPSLSLKSMTRI
PWAKLTSWAGPSPNPW*RWQTRRTAHPASHLSS
STTRSTVATPQLETCWRPSSCCRLDQQGRLTCPP
SMARWTWTEVPSCPCPWASGPCSASTEWRCCSG
AYGT*SG*TWPRWTGHGWTSSVQGRGCSRP*ST
IIRRTPTSTPSSSGLKWTSQRTSCCTRP*TSVWW
TAGPSVATHWWAPMPSAPCDASSTGPQTARPPA
GTPRSGFSGAAVCCAMGAPPLTPQGRLW*LWSQ
RY
PSRNWRPW*SWTRLLKLLSRWMWLRRRRRRRR
RRRALRRSQRRRSQTRACWTGGPSTLPPLTP*R
SNFDNKSPLELTWRRRRKWTIPRA*RGQ*RARR
RQGLPKRRRRRKLRALALARGPRPPRRRNPRLMS
LRYTPKSWSPSLITLRTGCTLSTCFGARPGMMR
MAPPRRSALWDASRAPSACTKCHSQRTCPGKPA
TTPPTACSRASRAMTPSMCWSESMWSGPRTCTLL
TSTAKLTPTSPSG*ARLTSATRRTTSPSSSTLS
LGSPLTSRPPSPWNPC*RWLCMTGTWWALMTSL
GKPRSTWRTASTASTAPPAASPRPTPHMATISGG
TP*SPARS*PASAKTAKWTAPTLGPLGE*RWPT
ASSLGPLRLRTRTVRGSPQTSMWRCWP*GTGRT
SPAQAAAWCQSMWRRGRCSTPTSRASSRAAWSCG
WTCSPWTCQPLGRLWTSHLGSPRSTSCGSSSGT
QMRWSWRTTTSSQGRSPVTSS*GGG*RASRRTS
RTQTSTTTPSLARATSTGATCSPSTTWRRRRRSS
SPRRSPCSPGTRPSTRSPRGSPCRSGMRTTSPL
TTSWGPSSWT*TGSRGAQRQPSSAPWRWPPGRW
TCPSCPSSSKSASKAGGPSWPAMRTMSLSSRARW
RLSCIY*QQRRQRRTQWAWPAMNLTP*RNPTGP
TRASSGS*TLSSRLATSCGTRIAGCSSNCCCSC
CCSSSSPCSSTLCLATWSRKSSGPEPSGLLAGPT
RPSSGSSTLSSPSSTSSAPGTSGSSSRSCWRCW
GCSCWGSSSTASLATWSKSSLGHEGRQLPPAAP
QPCRISFQWLGLFPISPGEPEEPSVHSSCLGPSL
PPACGGRLSSLPQAAACPVPPL*PLPVGWGALD
GVGTWNGSLLPHLAEAPPFFRPRLQRKTPETLP
RSSKYRIEALVKLTKDHGSVPRALKRMNEQKVSP
P*PLQIAPVFDPQQGPDPAHKSQRGCFCHCWAP
LGSSHFPGGRLSCLWVSMASQSSLCPSQRLQAQ
LRSCEKQQRGLPIPGTPCPPTPAPLPFQPFQLQL
GAGPSSAAPACVWVSVGCFSFLEW*FFSK*KKS
ST

Frame 1

REFCPGPVSSPEPQTHSPEVASSFRN*RTPMNT
NISRF*EQNLGN**LPHDDRYSGWP*RELPDHE
VPHSPDQQGGGIWGGWGGGAVAQHHPHS*FTGRR
PERHTGDDQNGEVLP*ASPAGRPGGAELWLLPL
PLPR*QGPGPLIPHQA*PGAPQVLHEGAGKHGA
AGQDAAGPGEAAHGAGQAEAVPELPAEAALPGGR
APAQHSRHLHLDDEQQQACRLCPCALQGPALLH
RGGGDWQGLRQGQDALP*AAREAGLRLGRLDSA
GQGGAVPVAGPQQTAQGVPVRPALWLPGGQGSPG
PGPACLPTRQPGLHQEAGVPAPSAHVPGPQPLC
RRQQRTLRPLCPRLLHQSESVHRGAE*DPVSHL
GPDAGVRQPGALW*SS*AEGRSAHHCH*NL*PGF
HGQS*LHGPDLRQTPGEDGRRGVLPTPLPTSAR
VLPDLPWQRHSWRPAGGLRAAADWTSREG*PAP
HQWPGGRGPRSHHARAHGHPARAQQVPSGGAVLG
PTGPKAGEPGPGGPATGGHRVCREGGAVVPDPQ
L*EEPQLQHPRQVV*SGPPRERAAAPALEHPCG
GLPGLRSLHTGGLPCRQLPATLHLPAPRPLGPQL
EHHGQASPALPCAVQWGLLLSLHRGGCGDYGAR
GT
HQETGDHGEAGRDF*SCCQGGCG*GGEGEEE
EEEGHCGGARGGGARREHAGLVVQVLCLH*HHEG
ATSTTRALWN*LGGEGGSGQYRGPEGVNEGQGE
GKGCQRGEEEENSELWLWPGVRGPREEETQD**
A*GIPQRAGVRV**L*GLAAHFQLASGQDRG**G
WLHRGGAHCGTLQGLPLRVQSATPRGRVPGSRL
RLHLRHVPGHPEQ*PHQCAGPSLCGPGHGPAPC
*HQRQS*PLHRHPARQD*HPRQGELHLQAAQPCL
WEVL*HRGLLPHGIHADGGCV*LGPGGH**PHW
GNQDRPGEPLLQQAPRHLRHRPDLLHTWLQYLA
GPHEAQPDPDPPLQRRQSGRPPLWAPWESEGGQP
RLHWAL*D*GRERSEEAHRRACGAVGPEALGGH
PPRRLPPGARACGDEAAAQPRQAGHRAGPPGAV
GGHVPHGHASPWDASGHLTSEAQEVRAAGHHLEH
R*GGLGGRRLLHRGEVQ*HLREGVAEGPAGGQA
GHRRPLPLPHWRGQLQLALPVPLRLPGGGGEDR
HLQEGVHVLLGRDRVQDPRAAHPADLGCGPLLR*
RLPGGHRAGPEPVPAGRKDSQAVHHGDGHRGGG
RAPRVHLQAKARQRLVAPPGPQ*ER*V*AHGQG
GG*AAFTDSRGGREEPSGPGPQ*T*PPRETQPAR
HELHLVPEPSQVGSLLLVAHVSLAAPQTVAAPA
AAPPPRPVPLLCAWLPGQENPRGLSPVASWPAR
HGLRLVPQPSQVHQVPHLHPVQVAHHQDRAGAVG
AAHVGALPLQPPWLHGQKAPWGMKAASSRQPLP
SPAAFPFSGLDSFPSPLGSLRSPASTLHALGRA
CLLLAGAACPHCPRLRLAQSRPSDPCLWAGEPWM
GWGPGMGLSCPTWLRRHPSSGPGSRGRLLKPSP
GLPSTGLKL**N*PRTMGQCPGL*KE*TSKRYP
RRDPCR*HRSLIRSRGQTLPTSPSAAASATAGLH
LAPLTSQGVACPACGFPWLPRAPSAPASASRPS
*GAVRSSRGDSPSRAHPVLPPLPPCPSSPFSCS
WELARQVLPLPVSGFLLAVFLFLSGDFSLNKRSQ
AL

Frame 2

VSSAQAL*AHQSHRLTAQRWLLPSGTEEPP*TP
TSPGSENRTWEIDDFLMMTDTQDGPSESSQIMR
SLTPLINREEAFGEAGEAGLWPSITHTPDSQEE
GLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRF
LSLADKDQGHSSRTRLDRERLKSCMRELENMGQ
QARMLRAQVKRHTVRDKLRLCQNFLQKLRFLAD
EPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSI
VEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQ
AKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQ
GLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFA
ADSSGLSDPFARVFFINQSQCTEVLNETLCPTW
DQMLVFDNLELYGEAHELRDDPPIIVIEIYDQD
SMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLE
YYQIYRGNATAGDLLAAFELLQIGPAGKADLPP
INGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFW
GLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHN
YKKNPNFNTLVKWFEVDLPENELLHPPLNIRVV
DCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPS
WNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPE
VP
IKKLETMVKLDATSEAVVKVDVAEEEKEKKK
KKKGTAEEPEEEEPDESMLDWWSKYFASIDTMK
EQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEK
ARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDE
LKVYPKELESEFDNFEDWLHTFNLLRGKTGDDE
DGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGY
DSTYGMFQGIPSNDPINVLVRVYVVRATDLHPA
DINGKADPYIAIRLGKTDIRDKENYISKQLNPV
FGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIG
ETKIDLENRFYSKHRATCGIAQTYSTHGYNIWR
DPMKPSQILTRLCKDGKVDGPHFGPPGRVKVAN
RVFTGPSEIEDENGQRKPTDEHVALLALRHWEDI
PRAGCRLVPEHVETRPLLNPDKPGIEQGRLELW
VDMFPMDMPAPGTPLDISPRKPKKYELRVIIWN
TDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQ
DTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIV
ISKKESMFSWDETEYKIPARLTLQIWDADHFSA
DDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVD
VPLVSIFKQKRVKGWWPLLARNENDEFELTGKV
EAELHLLTAEEAEKNPVGLARNEPDPLEKPNRP
DTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLL
LLLLLALFLYSVPGYLVKKILGA*AQWPPGRPD
TAFVWFLNPLKSIKYLICTRYKWLIIKIVLALL
GLLMLGLFLYSLPGYMVKKLLGA*RPPAPASRSP
ALPHFLSVAWTLSHLPWGA*GAQRPLFMPWAEP
ASCLRGPPVLTAPGCGLPSPAPLTPACGLGSLG
WGGDLEWVSLAPPG*GATLLQAQAPEEDS*NPPQ
VFQVQD*SFSEINQGPWVSAQGFKKNERAKGIP
AVTPADSTGL*SAAGARPCPQVPARLLLPLLGS
TWLLSLPRGSPVLPVGFHGFPELPLPQPAPPGPA
EEL*EAAEGTPHPGHTLSSHPCPLALPALSAAA
GSWPVKCCPCLCLGFCWLFFFS*VVIFL*IKEV
KH*

Sequence NM_194248

ATCGGAGGGGGGTCGGGAGGAGGAGGAGGAGGCAGCGGCAGAGAAGAGAGAGGCGTGTGAGCCGTGCTCCACCGGCTAGCTCCTTCCCGCTGCTCCTGCC
TGGCAGTGCCAGGCAGCCCACACCAGCATGGCCTTGCTCATCCACCTCAAGACAGTCTCGGAGCTGCGGGGCAGGGGCGACCGGATCGCCAAAGTGACTT
TCCGAGGGCAATCCTTCTACTCTCGGGTCCTGGAGAACTGTGAGGATGTGGCTGACTTTGATGAGACATTTCGGTGGCCGGTGGCCAGCAGCATCGACAG
AAATGAGATGCTGGAGATTCAGGTTTTCAACTACAGCAAAGTCTTCAGCAACAAGCTCATCGGGACCTTCCGCATGGTGCTGCAGAAGGTGGTAGAGGAG
AGCCATGTGGAGGTGACTGACACGCTGATTGATGACAACAATGCTATCATCAAGACCAGCCTGTGCGTGGAGGTCCGGTATCAGGCCACTGACGGCACAG
TGGGCTCCTGGGACGATGGGGACTTCCTGGGAGATGAGTCTCTTCAAGAGGAAGAGAAGGACAGCCAAGAGACGGATGGACTGCTCCCAGGCTCCCGGCC
CAGCTCCCGGCCCCCAGGAGAGAAGAGCTTCCGGAGAGCCGGGAGGAGCGTGTTCTCCGCCATGAAGCTCGGCAAAAACCGGTCTCACAAGGAGGAGCCC
CAAAGACCAGATGAACCGGCGGTGCTGGAGATGGAAGACCTTGACCATCTGGCCATTCGGCTAGGAGATGGACTGGATCCCGACTCGGTGTCTCTAGCCT
CAGTCACAGCTCTCACCACTAATGTCTCCAACAAGCGATCTAAGCCAGACATTAAGATGGAGCCAAGTGCTGGGCGGCCCATGGATTACCAGGTCAGCAT
CACGGTGATCGAGGCCCGGCAGCTGGTGGGCTTGAACATGGACCCTGTGGTGTGCGTGGAGGTGGGTGACGACAAGAAGTACACATCCATGAAGGAGTCC
ACTAACTGCCCCTATTACAACGAGTACTTCGTCTTCGACTTCCATGTCTCTCCGGATGTCATGTTTGACAAGATCATCAAGATTTCGGTGATTCACTCCA
AGAACCTGCTGCGCAGTGGCACCCTGGTGGGCTCCTTCAAAATGGACGTGGGAACCGTGTACTCGCAGCCAGAGCACCAGTTCCATCACAAGTGGGCCAT
CCTGTCTGACCCCGATGACATCTCCTCGGGGCTGAAGGGCTACGTGAAGTGTGACGTTGCCGTGGTGGGCAAAGGGGACAACATCAAGACGCCCCACAAG
GCCAATGAGACCGACGAAGATGACATTGAGGGGAACTTGCTGCTCCCCGAGGGGGTGCCCCCCGAACGCCAGTGGGCCCGGTTCTATGTGAAAATTTACC
GAGCAGAGGGGCTGCCCCGTATGAACACAAGCCTCATGGCCAATGTAAAGAAGGCTTTCATCGGTGAAAACAAGGACCTCGTGGACCCCTACGTGCAAGT
CTTCTTTGCTGGCCAGAAGGGCAAGACTTCAGTGCAGAAGAGCAGCTATGAGCCCCTGTGGAATGAGCAGGTCGTCTTTACAGACCTCTTCCCCCCACTC
TGCAAACGCATGAAGGTGCAGATCCGAGACTCGGACAAGGTCAACGACGTGGCCATCGGCACCCACTTCATTGACCTGCGCAAGATTTCTAATGACGGAG
ACAAAGGCTTCCTGCCCACACTGGGCCCAGCCTGGGTGAACATGTACGGCTCCACACGTAACTACACGCTGCTGGATGAGCATCAGGACCTGAACGAGGG
CCTGGGGGAGGGTGTGTCCTTCCGGGCCCGGCTCCTGCTGGGCCTGGCTGTGGAGATCGTAGACACCTCCAACCCTGAGCTCACCAGCTCCACAGAGGTG
CAGGTGGAGCAGGCCACGCCCATCTCGGAGAGCTGTGCAGGTAAAATGGAAGAATTCTTTCTCTTTGGAGCCTTCCTGGAGGCCTCAATGATCGACCGGA
GAAACGGAGACAAGCCCATCACCTTTGAGGTCACCATAGGCAACTATGGGAACGAAGTTGATGGCCTGTCCCGGCCCCAGCGGCCTCGGCCCCGGAAGGA
GCCGGGGGATGAGGAAGAAGTAGACCTGATTCAGAACGCAAGTGATGACGAGGCCGGTGATGCCGGGGACCTGGCCTCAGTCTCCTCCACTCCACCAATG
CGGCCCCAGGTCACCGACAGGAACTACTTCCATCTGCCCTACCTGGAGCGAAAGCCCTGCATCTACATCAAGAGCTGGTGGCCGGACCAGCGCCGCCGCC
TCTACAATGCCAACATCATGGACCACATTGCCGACAAGCTGGAAGAAGGCCTGAACGACATACAGGAGATGATCAAAACGGAGAAGTCCTACCCTGAGCG
TCGCCTGCGGGGCGTCCTGGAGGAGCTGAGCTGTGGCTGCTGCCGCTTCCTCTCCCTCGCTGACAAGGACCAGGGCCACTCATCCCGCACCAGGCTTGAC
CGGGAGCGCCTCAAGTCCTGCATGAGGGAGCTGGAAAACATGGGGCAGCAGGCCAGGATGCTGCGGGCCCAGGTGAAGCGGCACACGGTGCGGGACAAGC
TGAGGCTGTGCCAGAACTTCCTGCAGAAGCTGCGCTTCCTGGCGGACGAGCCCCAGCACAGCATTCCCGACATCTTCATCTGGATGATGAGCAACAACAA
GCGTGTCGCCTATGCCCGTGTGCCCTCCAAGGACCTGCTCTTCTCCATCGTGGAGGAGGAGACTGGCAAGGACTGCGCCAAGGTCAAGACGCTCTTCCTT
AAGCTGCCAGGGAAGCGGGGCTTCGGCTCGGCAGGCTGGACAGTGCAGGCCAAGGTGGAGCTGTACCTGTGGCTGGGCCTCAGCAAACAGCGCAAGGAGT
TCCTGTGCGGCCTGCCCTGTGGCTTCCAGGAGGTCAAGGCAGCCCAGGGCCTGGGCCTGCATGCCTTCCCACCCGTCAGCCTGGTCTACACCAAGAAGCA
GGCGTTCCAGCTCCGAGCGCACATGTACCAGGCCCGCAGCCTCTTTGCCGCCGACAGCAGCGGACTCTCAGACCCCTTTGCCCGCGTCTTCTTCATCAAT
CAGAGTCAGTGCACAGAGGTGCTGAATGAGACCCTGTGTCCCACCTGGGACCAGATGCTGGTGTTCGACAACCTGGAGCTCTATGGTGAAGCTCATGAGC
TGAGGGACGATCCGCCCATCATTGTCATTGAAATCTATGACCAGGATTCCATGGGCAAAGCTGACTTCATGGGCCGGACCTTCGCCAAACCCCTGGTGAA
GATGGCAGACGAGGCGTACTGCCCACCCCGCTTCCCACCTCAGCTCGAGTACTACCAGATCTACCGTGGCAACGCCACAGCTGGAGACCTGCTGGCGGCC
TTCGAGCTGCTGCAGATTGGACCAGCAGGGAAGGCTGACCTGCCCCCCATCAATGGCCCGGTGGACGTGGACCGAGGTCCCATCATGCCCGTGCCCATGG
GCATCCGGCCCGTGCTCAGCAAGTACCGAGTGGAGGTGCTGTTCTGGGGCCTACGGGACCTAAAGCGGGTGAACCTGGCCCAGGTGGACCGGCCACGGGT
GGACATCGAGTGTGCAGGGAAGGGGGTGCAGTCGTCCCTGATCCACAATTATAAGAAGAACCCCAACTTCAACACCCTCGTCAAGTGGTTTGAAGTGGAC
CTCCCAGAGAACGAGCTGCTGCACCCGCCCTTGAACATCCGTGTGGTGGACTGCCGGGCCTTCGGTCGCTACACACTGGTGGGCTCCCATGCCGTCAGCT
CCCTGCGACGCTTCATCTACCGGCCCCCAGACCGCTCGGCCCCCAGCTGGAACACCACGGTCAGGCTTCTCCGGCGCTGCCGTGTGCTGTGCAATGGGGG
CTCCTCCTCTCACTCCACAG
GGGAGGTTGTGGTGACTATGGAGCCAGAGGTACCCATCAAGAAACTGGAGACCATGGTGAAGCTGGACGCGACTTCTGAA
GCTGTTGTCAAGGTGGATGTGGCTGAGGAGGAGAAGGAGAAGAAGAAGAAGAAGAAGGGCACTGCGGAGGAGCCAGAGGAGGAGGAGCCAGACGAGAGCA
TGCTGGACTGGTGGTCCAAGTACTTTGCCTCCATTGACACCATGAAGGAGCAACTTCGACAACAAGAGCCCTCTGGAATTGACTTGGAGGAGAAGGAGGA
AGTGGACAATACCGAGGGCCTGAAGGGGTCAATGAAGGGCAAGGAGAAGGCAAGGGCTGCCAAAGAGGAGAAGAAGAAGAAAACTCAGAGCTCTGGCTCT
GGCCAGGGGTCCGAGGCCCCCGAGAAGAAGAAACCCAAGATTGATGAGCTTAAGGTATACCCCAAAGAGCTGGAGTCCGAGTTTGATAACTTTGAGGACT
GGCTGCACACTTTCAACTTGCTTCGGGGCAAGACCGGGGATGATGAGGATGGCTCCACCGAGGAGGAGCGCATTGTGGGACGCTTCAAGGGCTCCCTCTG
CGTGTACAAAGTGCCACTCCCAGAGGACGTGTCCCGGGAAGCCGGCTACGACTCCACCTACGGCATGTTCCAGGGCATCCCGAGCAATGACCCCATCAAT
GTGCTGGTCCGAGTCTATGTGGTCCGGGCCACGGACCTGCACCCTGCTGACATCAACGGCAAAGCTGACCCCTACATCGCCATCCGGCTAGGCAAGACTG
ACATCCGCGACAAGGAGAACTACATCTCCAAGCAGCTCAACCCTGTCTTTGGGAAGTCCTTTGACATCGAGGCCTCCTTCCCCATGGAATCCATGCTGAC
GGTGGCTGTGTATGACTGGGACCTGGTGGGCACTGATGACCTCATTGGGGAAACCAAGATCGACCTGGAGAACCGCTTCTACAGCAAGCACCGCGCCACC
TGCGGCATCGCCCAGACCTACTCCACACATGGCTACAATATCTGGCGGGACCCCATGAAGCCCAGCCAGATCCTGACCCGCCTCTGCAAAGACGGCAAAG
TGGACGGCCCCCACTTTGGGCCCCCTGGGAGAGTGAAGGTGGCCAACCGCGTCTTCACTGGGCCCTCTGAGATTGAGGACGAGAACGGTCAGAGGAAGCC
CACAGACGAGCATGTGGCGCTGTTGGCCCTGAGGCACTGGGAGGACATCCCCCGCGCAGGCTGCCGCCTGGTGCCAGAGCATGTGGAGACGAGGCCGCTG
CTCAACCCCGACAAGCCGGGCATCGAGCAGGGCCGCCTGGAGCTGTGGGTGGACATGTTCCCCATGGACATGCCAGCCCCTGGGACGCCTCTGGACATCT
CACCTCGGAAGCCCAAGAAGTACGAGCTGCGGGTCATCATCTGGAACACAGATGAGGTGGTCTTGGAGGACGACGACTTCTTCACAGGGGAGAAGTCCAG
TGACATCTTCGTGAGGGGGTGGCTGAAGGGCCAGCAGGAGGACAAGCAGGACACAGACGTCCACTACCACTCCCTCACTGGCGAGGGCAACTTCAACTGG
CGCTACCTGTTCCCCTTCGACTACCTGGCGGCGGAGGAGAAGATCGTCATCTCCAAGAAGGAGTCCATGTTCTCCTGGGACGAGACCGAGTACAAGATCC
CCGCGCGGCTCACCCTGCAGATCTGGGATGCGGACCACTTCTCCGCTGACGACTTCCTGGGGGCCATCGAGCTGGACCTGAACCGGTTCCCGCGGGGCGC
AAAGACAGCCAAGCAGTGCACCATGGAGATGGCCACCGGGGAGGTGGACGTGCCCCTCGTGTCCATCTTCAAGCAAAAGCGCGTCAAAGGCTGGTGGCCC
CTCCTGGCCCGCAATGAGAACGATGAGTTTGAGCTCACGGGCAAGGTGGAGGCTGAGCTGCATTTACTGACAGCAGAGGAGGCAGAGAAGAACCCAGTGG
GCCTGGCCCGCAATGAACCTGACCCCCTAGAGAAACCCAACCGGCCCGACACGAGCTTCATCTGGTTCCTGAACCCTCTCAAGTCGGCTCGCTACTTCTT
GTGGCACACGTATCGCTGGCTGCTCCTCAAACTGTTGCTGCTCCTGCTGCTGCTCCTCCTCCTCGCCCTGTTCCTCTACTCTGTGCCTGGCTACCTGGTC
AAGAAAATCCTCGGGGCCTGAGCCCAGTGGCCTCCTGGCCGGCCCGACACGGCCTTCGTCTGGTTCCTCAACCCTCTCAAGTCCATCAAGTACCTCATCT
GCACCCGGTACAAGTGGCTCATCATCAAGATCGTGCTGGCGCTGTTGGGGCTGCTCATGTTGGGGCTCTTCCTCTACAGCCTCCCTGGCTACATGGTCAA
AAAGCTCCTTGGGGCATGAAGGCCGCCAGCTCCCGCCAGCCGCTCCCCAGCCCTGCCGCATTTCCTTTCAGTGGCTTGGACTCTTTCCCATCTCCCCTGG
GGAGCCTGAGGAGCCCAGCGTCCACTCTTCATGCCTTGGGCCGAGCCTGCCTCCTGCTTGCGGGGGCCGCCTGTCCTCACTGCCCCAGGCTGCGGCTTGC
CCAGTCCCGCCCCTCTGACCCCTGCCTGTGGGCTGGGGAGCCTTGGATGGGGTGGGGACCTGGAATGGGTCTCTCTTGCCCCACCTGGCTGAGGCGCCAC
CCTTCTTCAGGCCCAGGCTCCAGAGGAAGACTCCTGAAACCCTCCCCAGGTCTTCCAAGTACAGGATTGAAGCTTTAGTGAAATTAACCAAGGACCATGG
GTCAGTGCCCAGGGCTTTAAAAAGAATGAACGAGCAAAAGGTATCCCCGCCGTGACCCCTGCAGATAGCACCGGTCTTTGATCCGCAGCAGGGGCCAGAC
CCTGCCCACAAGTCCCAGCGCGGCTGCTTCTGCCACTGCTGGGCTCCACTTGGCTCCTCTCACTTCCCAGGGGGTCGCCTGTCCTGCCTGTGGGTTTCCA
TGGCTTCCCAGAGCTCCCTCTGCCCCAGCCAGCGCCTCCAGGCCCAGCTGAGGAGCTGTGAGAAGCAGCAGAGGGGACTCCCCATCCCGGGCACACCCTG
TCCTCCCACCCCTGCCCCCTTGCCCTTCCAGCCCTTTCAGCTGCAGCTGGGAGCTGGCCCGTCAAGTGCTGCCCCTGCCTGTGTCTGGGTTTCTGTTGGC
TGTTTTTCTTTTCTTGAGTGGTGATTTTTCTCTAAATAAAAGAAGTCAAGCACTGA
  • refseq_OTOF.F3 (forward primer)
  • refseq_OTOF.R3 (reverse primer)
  • Alternative acceptor

Frame 0

IGGGSGGGGGGSGREERGV*AVLHRLAPSRCSC
LAVPGSPHQHGLAHPPQDSLGAAGQGRPDRQSDF
PRAILLLSGPGEL*GCG*L**DISVAGGQQHRQ
K*DAGDSGFQLQQSLQQQAHRDLPHGAAEGGRG
EPCGGD*HAD**QQCYHQDQPVRGGPVSGH*RHS
GLLGRWGLPGR*VSSRGREGQPRDGWTAPRLPA
QLPAPRREELPESREERVLRHEARQKPVSQGGA
PKTR*TGGAGDGRP*PSGHSARRWTGSRLGVSSL
SHSSHH*CLQQAI*ARH*DGAKCWAAHGLPGQH
HGDRGPAAGGLEHGPCGVRGGG*RQEVHIHEGV
H*LPLLQRVLRLRLPCLSGCHV*QDHQDFGDSLQ
EPAAQWHPGGLLQNGRGNRVLAARAPVPSQVGH
PV*PR*HLLGAEGLREV*RCRGGQRGQHQDAPQ
GQ*DRRR*H*GELAAPRGGAPRTPVGPVLCENLP
SRGAAPYEHKPHGQCKEGFHR*KQGPRGPLRAS
LLCWPEGQDFSAEEQL*APVE*AGRLYRPLPPT
LQTHEGADPRLGQGQRRGHRHPLH*PAQDF**RR
QRLPAHTGPSLGEHVRLHT*LHAAG*ASGPERG
PGGGCVLPGPAPAGPGCGDRRHLQP*AHQLHRG
AGGAGHAHLGELCR*NGRILSLWSLPGGLNDRPE
KRRQAHHL*GHHRQLWERS*WPVPAPAASAPEG
AGG*GRSRPDSERK**RGR*CRGPGLSLLHSTN
AAPGHRQELLPSALPGAKALHLHQELVAGPAPPP
LQCQHHGPHCRQAGRRPERHTGDDQNGEVLP*A
SPAGRPGGAELWLLPLPLPR*QGPGPLIPHQA*
PGAPQVLHEGAGKHGAAGQDAAGPGEAAHGAGQA
EAVPELPAEAALPGGRAPAQHSRHLHLDDEQQQ
ACRLCPCALQGPALLHRGGGDWQGLRQGQDALP
*AAREAGLRLGRLDSAGQGGAVPVAGPQQTAQGV
PVRPALWLPGGQGSPGPGPACLPTRQPGLHQEA
GVPAPSAHVPGPQPLCRRQQRTLRPLCPRLLHQ
SESVHRGAE*DPVSHLGPDAGVRQPGALW*SS*A
EGRSAHHCH*NL*PGFHGQS*LHGPDLRQTPGE
DGRRGVLPTPLPTSARVLPDLPWQRHSWRPAGG
LRAAADWTSREG*PAPHQWPGGRGPRSHHARAHG
HPARAQQVPSGGAVLGPTGPKAGEPGPGGPATG
GHRVCREGGAVVPDPQL*EEPQLQHPRQVV*SG
PPRERAAAPALEHPCGGLPGLRSLHTGGLPCRQL
PATLHLPAPRPLGPQLEHHGQASPALPCAVQWG
LLLSLHR
GGCGDYGARGTHQETGDHGEAGRDF*
SCCQGGCG*GGEGEEEEEEGHCGGARGGGARREH
AGLVVQVLCLH*HHEGATSTTRALWN*LGGEGG
SGQYRGPEGVNEGQGEGKGCQRGEEEENSELWL
WPGVRGPREEETQD**A*GIPQRAGVRV**L*GL
AAHFQLASGQDRG**GWLHRGGAHCGTLQGLPL
RVQSATPRGRVPGSRLRLHLRHVPGHPEQ*PHQ
CAGPSLCGPGHGPAPC*HQRQS*PLHRHPARQD*
HPRQGELHLQAAQPCLWEVL*HRGLLPHGIHAD
GGCV*LGPGGH**PHWGNQDRPGEPLLQQAPRH
LRHRPDLLHTWLQYLAGPHEAQPDPDPPLQRRQS
GRPPLWAPWESEGGQPRLHWAL*D*GRERSEEA
HRRACGAVGPEALGGHPPRRLPPGARACGDEAA
AQPRQAGHRAGPPGAVGGHVPHGHASPWDASGHL
TSEAQEVRAAGHHLEHR*GGLGGRRLLHRGEVQ
*HLREGVAEGPAGGQAGHRRPLPLPHWRGQLQL
ALPVPLRLPGGGGEDRHLQEGVHVLLGRDRVQDP
RAAHPADLGCGPLLR*RLPGGHRAGPEPVPAGR
KDSQAVHHGDGHRGGGRAPRVHLQAKARQRLVA
PPGPQ*ER*V*AHGQGGG*AAFTDSRGGREEPSG
PGPQ*T*PPRETQPARHELHLVPEPSQVGSLLL
VAHVSLAAPQTVAAPAAAPPPRPVPLLCAWLPG
QENPRGLSPVASWPARHGLRLVPQPSQVHQVPHL
HPVQVAHHQDRAGAVGAAHVGALPLQPPWLHGQ
KAPWGMKAASSRQPLPSPAAFPFSGLDSFPSPL
GSLRSPASTLHALGRACLLLAGAACPHCPRLRLA
QSRPSDPCLWAGEPWMGWGPGMGLSCPTWLRRH
PSSGPGSRGRLLKPSPGLPSTGLKL**N*PRTM
GQCPGL*KE*TSKRYPRRDPCR*HRSLIRSRGQT
LPTSPSAAASATAGLHLAPLTSQGVACPACGFP
WLPRAPSAPASASRPS*GAVRSSRGDSPSRAHP
VLPPLPPCPSSPFSCSWELARQVLPLPVSGFLLA
VFLFLSGDFSLNKRSQAL

Frame 1

SEGGREEEEEAAAEKREACEPCSTG*LLPAAPA
WQCQAAHTSMALLIHLKTVSELRGRGDRIAKVT
FRGQSFYSRVLENCEDVADFDETFRWPVASSIDR
NEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEE
SHVEVTDTLIDDNNAIIKTSLCVEVRYQATDGT
VGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRP
SSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEP
QRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLA
SVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSI
TVIEARQLVGLNMDPVVCVEVGDDKKYTSMKES
TNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHS
KNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAI
LSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHK
ANETDEDDIEGNLLLPEGVPPERQWARFYVKIY
RAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQV
FFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPL
CKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDG
DKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEG
LGEGVSFRARLLLGLAVEIVDTSNPELTSSTEV
QVEQATPISESCAGKMEEFFLFGAFLEASMIDR
RNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKE
PGDEEEVDLIQNASDDEAGDAGDLASVSSTPPM
RPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRR
LYNANIMDHIADKLEEGLNDIQEMIKTEKSYPER
RLRGVLEELSCGCCRFLSLADKDQGHSSRTRLD
RERLKSCMRELENMGQQARMLRAQVKRHTVRDK
LRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNK
RVAYARVPSKDLLFSIVEEETGKDCAKVKTLFL
KLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKE
FLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQ
AFQLRAHMYQARSLFAADSSGLSDPFARVFFIN
QSQCTEVLNETLCPTWDQMLVFDNLELYGEAHE
LRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVK
MADEAYCPPRFPPQLEYYQIYRGNATAGDLLAA
FELLQIGPAGKADLPPINGPVDVDRGPIMPVPM
GIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRV
DIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVD
LPENELLHPPLNIRVVDCRAFGRYTLVGSHAVS
SLRRFIYRPPDRSAPSWNTTVRLLRRCRVLCNGG
SSSHST
GEVVVTMEPEVPIKKLETMVKLDATSE
AVVKVDVAEEEKEKKKKKKGTAEEPEEEEPDES
MLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEE
VDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGS
GQGSEAPEKKKPKIDELKVYPKELESEFDNFED
WLHTFNLLRGKTGDDEDGSTEEERIVGRFKGSLC
VYKVPLPEDVSREAGYDSTYGMFQGIPSNDPIN
VLVRVYVVRATDLHPADINGKADPYIAIRLGKT
DIRDKENYISKQLNPVFGKSFDIEASFPMESMLT
VAVYDWDLVGTDDLIGETKIDLENRFYSKHRAT
CGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGK
VDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKP
TDEHVALLALRHWEDIPRAGCRLVPEHVETRPL
LNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDI
SPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSS
DIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNW
RYLFPFDYLAAEEKIVISKKESMFSWDETEYKI
PARLTLQIWDADHFSADDFLGAIELDLNRFPRGA
KTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWP
LLARNENDEFELTGKVEAELHLLTAEEAEKNPV
GLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFL
WHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLV
KKILGA*AQWPPGRPDTAFVWFLNPLKSIKYLI
CTRYKWLIIKIVLALLGLLMLGLFLYSLPGYMVK
KLLGA*RPPAPASRSPALPHFLSVAWTLSHLPW
GA*GAQRPLFMPWAEPASCLRGPPVLTAPGCGL
PSPAPLTPACGLGSLGWGGDLEWVSLAPPG*GAT
LLQAQAPEEDS*NPPQVFQVQD*SFSEINQGPW
VSAQGFKKNERAKGIPAVTPADSTGL*SAAGAR
PCPQVPARLLLPLLGSTWLLSLPRGSPVLPVGFH
GFPELPLPQPAPPGPAEEL*EAAEGTPHPGHTL
SSHPCPLALPALSAAAGSWPVKCCPCLCLGFCW
LFFFS*VVIFL*IKEVKH*

Frame 2

RRGVGRRRRRQRQRRERRVSRAPPASSFPLLLP
GSARQPTPAWPCSSTSRQSRSCGAGATGSPK*L
SEGNPSTLGSWRTVRMWLTLMRHFGGRWPAAST
EMRCWRFRFSTTAKSSATSSSGPSAWCCRRW*RR
AMWR*LTR*LMTTMLSSRPACAWRSGIRPLTAQ
WAPGTMGTSWEMSLFKRKRRTAKRRMDCSQAPG
PAPGPQERRASGEPGGACSPP*SSAKTGLTRRSP
KDQMNRRCWRWKTLTIWPFG*EMDWIPTRCL*P
QSQLSPLMSPTSDLSQTLRWSQVLGGPWITRSA
SR*SRPGSWWA*TWTLWCAWRWVTTRSTHP*RSP
LTAPITTSTSSSTSMSLRMSCLTRSSRFR*FTP
RTCCAVAPWWAPSKWTWEPCTRSQSTSSITSGP
SCLTPMTSPRG*RAT*SVTLPWWAKGTTSRRPTR
PMRPTKMTLRGTCCSPRGCPPNASGPGSM*KFT
EQRGCPV*TQASWPM*RRLSSVKTRTSWTPTCK
SSLLARRARLQCRRAAMSPCGMSRSSLQTSSPHS
ANA*RCRSETRTRSTTWPSAPTSLTCARFLMTE
TKASCPHWAQPG*TCTAPHVTTRCWMSIRT*TR
AWGRVCPSGPGSCWAWLWRS*TPPTLSSPAPQRC
RWSRPRPSRRAVQVKWKNSFSLEPSWRPQ*STG
ETETSPSPLRSP*ATMGTKLMACPGPSGLGPGR
SRGMRKK*T*FRTQVMTRPVMPGTWPQSPPLHQC
GPRSPTGTTSICPTWSESPASTSRAGGRTSAAA
STMPTSWTTLPTSWKKA*TTYRR*SKRRSPTLS
VACGASWRS*AVAAAASSPSLTRTRATHPAPGLT
GSASSPA*GSWKTWGSRPGCCGPR*SGTRCGTS
*GCARTSCRSCASWRTSPSTAFPTSSSG**ATT
SVSPMPVCPPRTCSSPSWRRRLARTAPRSRRSSL
SCQGSGASARQAGQCRPRWSCTCGWASANSARS
SCAACPVASRRSRQPRAWACMPSHPSAWSTPRS
RRSSSERTCTRPAASLPPTAADSQTPLPASSSSI
RVSAQRC*MRPCVPPGTRCWCSTTWSSMVKLMS
*GTIRPSLSLKSMTRIPWAKLTSWAGPSPNPW*
RWQTRRTAHPASHLSSSTTRSTVATPQLETCWRP
SSCCRLDQQGRLTCPPSMARWTWTEVPSCPCPW
ASGPCSASTEWRCCSGAYGT*SG*TWPRWTGHG
WTSSVQGRGCSRP*STIIRRTPTSTPSSSGLKWT
SQRTSCCTRP*TSVWWTAGPSVATHWWAPMPSA
PCDASSTGPQTARPPAGTPRSGFSGAAVCCAMG
APPLTPQ
GRLW*LWSQRYPSRNWRPW*SWTRLLK
LLSRWMWLRRRRRRRRRRRALRRSQRRRSQTRA
CWTGGPSTLPPLTP*RSNFDNKSPLELTWRRRR
KWTIPRA*RGQ*RARRRQGLPKRRRRRKLRALAL
ARGPRPPRRRNPRLMSLRYTPKSWSPSLITLRT
GCTLSTCFGARPGMMRMAPPRRSALWDASRAPS
ACTKCHSQRTCPGKPATTPPTACSRASRAMTPSM
CWSESMWSGPRTCTLLTSTAKLTPTSPSG*ARL
TSATRRTTSPSSSTLSLGSPLTSRPPSPWNPC*
RWLCMTGTWWALMTSLGKPRSTWRTASTASTAPP
AASPRPTPHMATISGGTP*SPARS*PASAKTAK
WTAPTLGPLGE*RWPTASSLGPLRLRTRTVRGS
PQTSMWRCWP*GTGRTSPAQAAAWCQSMWRRGRC
STPTSRASSRAAWSCGWTCSPWTCQPLGRLWTS
HLGSPRSTSCGSSSGTQMRWSWRTTTSSQGRSP
VTSS*GGG*RASRRTSRTQTSTTTPSLARATSTG
ATCSPSTTWRRRRRSSSPRRSPCSPGTRPSTRS
PRGSPCRSGMRTTSPLTTSWGPSSWT*TGSRGA
QRQPSSAPWRWPPGRWTCPSCPSSSKSASKAGGP
SWPAMRTMSLSSRARWRLSCIY*QQRRQRRTQW
AWPAMNLTP*RNPTGPTRASSGS*TLSSRLATS
CGTRIAGCSSNCCCSCCCSSSSPCSSTLCLATWS
RKSSGPEPSGLLAGPTRPSSGSSTLSSPSSTSS
APGTSGSSSRSCWRCWGCSCWGSSSTASLATWS
KSSLGHEGRQLPPAAPQPCRISFQWLGLFPISPG
EPEEPSVHSSCLGPSLPPACGGRLSSLPQAAAC
PVPPL*PLPVGWGALDGVGTWNGSLLPHLAEAP
PFFRPRLQRKTPETLPRSSKYRIEALVKLTKDHG
SVPRALKRMNEQKVSPP*PLQIAPVFDPQQGPD
PAHKSQRGCFCHCWAPLGSSHFPGGRLSCLWVS
MASQSSLCPSQRLQAQLRSCEKQQRGLPIPGTPC
PPTPAPLPFQPFQLQLGAGPSSAAPACVWVSVG
CFSFLEW*FFSK*KKSST

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