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Sequences

Sequence NM_181839

CGCTATGCAGAGAAAGCCCCCCTGGCTCTTCTCTCTCAATCCATAATCCAGCGATGCTGCAGCTGTAAAAGCATTAATAGAAAATCAATCCACAACCTCG
CGGGGCAGCGATCGTCGAGCGCCGTTTCCAGGCTGCCTTCCCTGGGGTCGGGAGCGGCCCCGCTCCCCCCGTGGCTGGCGCGGAATGTGGTGATCCGTCC
C
GGGGCGGGGATGACTTCATGCAGCCGGAGCTCCGCGGCGGGAGCGGAGGCTGCTGCTGGCAGGTGGGGCGCGGGCCGGCGCGAGCTGACCGAGCACTCG
GCGGGCGCGGCGGGACTGCGGCCCGTGGCGGCGTGCGCGGGGACCTGCGCTGACTAGGTCCGGGGAAGTCCCTGCTATGTGGATATTTGGTAGCAATGAC
TGATGTGGAA
ACTACATATGCAGATTTTATTGCTTCAGGAAGAACAGGTAGAAGAAATGCAATACATGATATCCTGGTTTCCTCTGCAAGTGGCAACAGC
AATGAATTAGCCTTGAAATTAGCAGGTCTTGATATCAACAAGACAGAAGGTGAAGAAGATGCACAACGAAGTTCTACAGAACAAAGTGGGGAAGCCCAGG
GAGAAGCAGCAAAATCTGAAAGCTAACACCCCACTTTGACCCTCGACCACACCTGAAAATGTCTCAAATCTCCAGGAGTATCTGGAATGCATTTGTTTCC
ATGAGTGAAAAGAGGAAAAAGAAAATGGCTGTGCTGCATTGCAGGAACCTGCTCATTATCATGTTAAAAATGAGGGCAGAGGCTGTGGCTGCAGGCAGAC
TTTTCCCTACCTCTGTCATTAGCAATGGTTGAAATCATGTGGCTTGTGTTTGGGCGTCATTTTTGTATGGATCCTTTCACTTGATCATATGACGAAATGC
TTATAGAGAGTAGCTCCGACCTAGATGATGATTCTTCCTGTAGCATCTGGCCCCTCACAATGTCAGAGGATTTAATTGTGTCTAATTGCGAAGGGTTGAT
TGAACCCCAGAGTTTAAATATCTCTGGCTCAAGTGTTCACCCAGTAAAAGAAAGATCCAGAAAGCACTGTTTTTAGCATTACGTATCTGTGTGTTACTGC
TGTGTTATTTACACTGTTTTGTATTGTACAATATATATGCTCAGCACTGCCCCCTTCTCTGATTGCTTATGAAAAACAAAATGATGTACATTACTGTGAA
TTTTTATACCACTCATTTTTAAAAGGGCTGTCTTTTCATTTTAGTTTTCCATACTGTGGTGGTGTACACAGGATAGAACACCCTTTTTTAAAACACAGTC
TTTCCCCTTGCTCATTGTATGTTGATGAGTTGATTAAGTCTAACAGATTCATCAAGACTCCATTGCTTTATTATAGAGACATTTGAAAATATCCATTAAT
GTGAATATCACCTGAATTCAGTCTGTTTGGTGTCTGCACAGACTGGAATTCAATCTGTCAAATTTGTTTTATTCTCAAGTGGAGAACTTCTCCCACATAA
TATATATATATATATATATTTTAATTTATGAGAATTTTGGACAATTGGAAAGGTAGAAAAGAAAAGCCAAGATCATACTAAGGACTGGAAATATTTTGTT
CTATGGAATCAAATTTCTCACAATGCTGTATGATACTATTTAAATTTGGAGGACAACTTATCTTCACTAAGCTGAATCAGGTGGAGAAAGTAATCTCCTT
GCAATCATGTGGACACCAATCACAAAAGTAAAGCCCTGGTGTTGTGTTTTCATGTCTTTTTTCAGCCCTCTCAGATCCAAATGTTATTATGCACTTTTTA
ATGTTTGTAAACTTTTACTAATAATTAGTGTGAATTGCATTCTGATACAATAATGATTATCATTAGAAGCTAACAAAATTCTCATTAATACTGTGTTTGA
TGGCCTCTGCTGTGTTTTAACATCGTGCTTCTTATATGGAAAGTTTTTGTGAGCTGTGTAATCCCTCTGGTCAGTATTATGAAATCATTTGTCAGTGGTA
ATAAATAAGGAACCAGTAATATGCCAATGGTTCATGAATTACTGGACAAATAGCA
  • refseq_PKIA.F1 (forward primer)
  • refseq_PKIA.R1 (reverse primer)
  • Single exon skipping

Frame 0

RYAEKAPLALLSQSIIQRCCSCKSINRKSIHNL
AGQRSSSAVSRLPSLGSGAAPLPPWLARNVVIRP
GAGMTSCSRSSAAGAEAAAGRWGAGRRELTEHS
AGAAGLRPVAACAGTCAD*VRGSPCYVDIW*Q*
LMWK
LHMQILLLQEEQVEEMQYMISWFPLQVATA
MN*P*N*QVLISTRQKVKKMHNEVLQNKVGKPR
EKQQNLKANTPL*PSTTPENVSNLQEYLECICF
HE*KEEKENGCAALQEPAHYHVKNEGRGCGCRQT
FPYLCH*QWLKSCGLCLGVIFVWILSLDHMTKC
L*RVAPT*MMILPVASGPSQCQRI*LCLIAKG*
LNPRV*ISLAQVFTQ*KKDPESTVFSITYLCVTA
VLFTLFCIVQYICSALPPSLIAYEKQNDVHYCE
FLYHSFLKGLSFHFSFPYCGGVHRIEHPFLKHS
LSPCSLYVDELIKSNRFIKTPLLYYRDI*KYPLM
*ISPEFSLFGVCTDWNSICQICFILKWRTSPT*
YIYIYIF*FMRILDNWKGRKEKPRSY*GLEIFC
SMESNFSQCCMILFKFGGQLIFTKLNQVEKVISL
QSCGHQSQK*SPGVVFSCLFSALSDPNVIMHFL
MFVNFY**LV*IAF*YNNDYH*KLTKFSLILCL
MASAVF*HRASYMESFCELCNPSGQYYEIICQW*
*IRNQ*YANGS*ITGQIA

Frame 1

AMQRKPPWLFSLNP*SSDAAAVKALIENQSTTS
RGSDRRAPFPGCLPWGRERPRSPRGWRGMW*SV
P
GRG*LHAAGAPRRERRLLLAGGARAGAS*PSTR
RARRDCGPWRRARGPALTRSGEVPAMWIFGSND
*CG
NYICRFYCFRKNR*KKCNT*YPGFLCKWQQ
Q*ISLEISRS*YQQDRR*RRCTTKFYRTKWGSPG
RSSKI*KLTPHFDPRPHLKMSQISRSIWNAFVS
MSEKRKKKMAVLHCRNLLIIMLKMRAEAVAAGR
LFPTSVISNG*NHVACVWASFLYGSFHLII*RNA
YRE*LRPR**FFL*HLAPHNVRGFNCV*LRRVD
*TPEFKYLWLKCSPSKRKIQKALFLALRICVLL
LCYLHCFVLYNIYAQHCPLL*LLMKNKMMYITVN
FYTTHF*KGCLFILVFHTVVVYTG*NTLF*NTV
FPLAHCMLMS*LSLTDSSRLHCFIIETFENIH*
CEYHLNSVCLVSAQTGIQSVKFVLFSSGELLPHN
IYIYIYFNL*EFWTIGKVEKKSQDHTKDWKYFV
LWNQISHNAV*YYLNLEDNLSSLS*IRWRK*SP
CNHVDTNHKSKALVLCFHVFFQPSQIQMLLCTF*
CL*TFTNN*CELHSDTIMIIIRS*QNSH*YCV*
WPLLCFNIVLLIWKVFVSCVIPLVSIMKSFVSG
NK*GTSNMPMVHELLDK*

Frame 2

LCRESPPGSSLSIHNPAMLQL*KH**KINPQPR
GAAIVERRFQAAFPGVGSGPAPPVAGAECGDPS
RGGDDFMQPELRGGSGGCCWQVGRGPARADRAL
GGRGGTAARGGVRGDLR*LGPGKSLLCGYLVAMT
DVE
TTYADFIASGRTGRRNAIHDILVSSASGNS
NELALKLAGLDINKTEGEEDAQRSSTEQSGEAQ
GEAAKSES*HPTLTLDHT*KCLKSPGVSGMHLFP
*VKRGKRKWLCCIAGTCSLSC*K*GQRLWLQAD
FSLPLSLAMVEIMWLVFGRHFCMDPFT*SYDEM
LIESSSDLDDDSSCSIWPLTMSEDLIVSNCEGLI
EPQSLNISGSSVHPVKERSRKHCF*HYVSVCYC
CVIYTVLYCTIYMLSTAPFSDCL*KTK*CTLL*
IFIPLIFKRAVFSF*FSILWWCTQDRTPFFKTQS
FPLLIVC**VD*V*QIHQDSIALL*RHLKISIN
VNIT*IQSVWCLHRLEFNLSNLFYSQVENFSHI
IYIYIYILIYENFGQLER*KRKAKIILRTGNILF
YGIKFLTMLYDTI*IWRTTYLH*AESGGESNLL
AIMWTPITKVKPWCCVFMSFFSPLRSKCYYALF
NVCKLLLIISVNCILIQ**LSLEANKILINTVFD
GLCCVLTSCFLYGKFL*AV*SLWSVL*NHLSVV
INKEPVICQWFMNYWTNS

Sequence NM_006823

CGCTATGCAGAGAAAGCCCCCCTGGCTCTTCTCTCTCAATCCATAATCCAGCGATGCTGCAGCTGTAAAAGCATTAATAGAAAATCAATCCACAACCTCG
CGGGGCAGCGATCGTCGAGCGCCGTTTCCAGGCTGCCTTCCCTGGGGTCGGGAGCGGCCCCGCTCCCCCCGTGGCTGGCGCGGAATGTGGTGATCCGTCC
C
GGGGCGGGGATGACTTCATGCAGCCGGAGCTCCGCGGCGGGAGCGGAGGCTGCTGCTGGCAGGTGGGGCGCGGGCCGGCGCGAGCTGACCGAGCACTCG
GCGGGCGCGGCGGGACTGCGGCCCGTGGCGGCGTGCGCGGGGACCTGCGCTGACTAGGTCCGGGGAAGTTTCCTGACTTTCTGAGAAGCCCTGGTTTCCC
CAAAGAAGTGATTTCTGATAGAAATCTGAAGGTCATCTCCAAGAAAAAAGAGATCTAGTATAGTCAATGAATTAAAGACAAGAAGGTTTCCAATCAG
TCC
CTGCTATGTGGATATTTGGTAGCAATGACTGATGTGGAAACTACATATGCAGATTTTATTGCTTCAGGAAGAACAGGTAGAAGAAATGCAATACATGATA
TCCTGGTTTCCTCTGCAAGTGGCAACAGCAATGAATTAGCCTTGAAATTAGCAGGTCTTGATATCAACAAGACAGAAGGTGAAGAAGATGCACAACGAAG
TTCTACAGAACAAAGTGGGGAAGCCCAGGGAGAAGCAGCAAAATCTGAAAGCTAACACCCCACTTTGACCCTCGACCACACCTGAAAATGTCTCAAATCT
CCAGGAGTATCTGGAATGCATTTGTTTCCATGAGTGAAAAGAGGAAAAAGAAAATGGCTGTGCTGCATTGCAGGAACCTGCTCATTATCATGTTAAAAAT
GAGGGCAGAGGCTGTGGCTGCAGGCAGACTTTTCCCTACCTCTGTCATTAGCAATGGTTGAAATCATGTGGCTTGTGTTTGGGCGTCATTTTTGTATGGA
TCCTTTCACTTGATCATATGACGAAATGCTTATAGAGAGTAGCTCCGACCTAGATGATGATTCTTCCTGTAGCATCTGGCCCCTCACAATGTCAGAGGAT
TTAATTGTGTCTAATTGCGAAGGGTTGATTGAACCCCAGAGTTTAAATATCTCTGGCTCAAGTGTTCACCCAGTAAAAGAAAGATCCAGAAAGCACTGTT
TTTAGCATTACGTATCTGTGTGTTACTGCTGTGTTATTTACACTGTTTTGTATTGTACAATATATATGCTCAGCACTGCCCCCTTCTCTGATTGCTTATG
AAAAACAAAATGATGTACATTACTGTGAATTTTTATACCACTCATTTTTAAAAGGGCTGTCTTTTCATTTTAGTTTTCCATACTGTGGTGGTGTACACAG
GATAGAACACCCTTTTTTAAAACACAGTCTTTCCCCTTGCTCATTGTATGTTGATGAGTTGATTAAGTCTAACAGATTCATCAAGACTCCATTGCTTTAT
TATAGAGACATTTGAAAATATCCATTAATGTGAATATCACCTGAATTCAGTCTGTTTGGTGTCTGCACAGACTGGAATTCAATCTGTCAAATTTGTTTTA
TTCTCAAGTGGAGAACTTCTCCCACATAATATATATATATATATATATTTTAATTTATGAGAATTTTGGACAATTGGAAAGGTAGAAAAGAAAAGCCAAG
ATCATACTAAGGACTGGAAATATTTTGTTCTATGGAATCAAATTTCTCACAATGCTGTATGATACTATTTAAATTTGGAGGACAACTTATCTTCACTAAG
CTGAATCAGGTGGAGAAAGTAATCTCCTTGCAATCATGTGGACACCAATCACAAAAGTAAAGCCCTGGTGTTGTGTTTTCATGTCTTTTTTCAGCCCTCT
CAGATCCAAATGTTATTATGCACTTTTTAATGTTTGTAAACTTTTACTAATAATTAGTGTGAATTGCATTCTGATACAATAATGATTATCATTAGAAGCT
AACAAAATTCTCATTAATACTGTGTTTGATGGCCTCTGCTGTGTTTTAACATCGTGCTTCTTATATGGAAAGTTTTTGTGAGCTGTGTAATCCCTCTGGT
CAGTATTATGAAATCATTTGTCAGTGGTAATAAATAAGGAACCAGTAATATGCCAATGGTTCATGAATTACTGGACAAATAGCA
  • refseq_PKIA.F1 (forward primer)
  • refseq_PKIA.R1 (reverse primer)
  • Single exon skipping

Frame 0

RYAEKAPLALLSQSIIQRCCSCKSINRKSIHNL
AGQRSSSAVSRLPSLGSGAAPLPPWLARNVVIRP
GAGMTSCSRSSAAGAEAAAGRWGAGRRELTEHS
AGAAGLRPVAACAGTCAD*VRGSFLTF*EALVS
PKK*FLIEI*RSSPRKKRSSIVNELKTRRFPIS
P
CYVDIW*Q*LMWKLHMQILLLQEEQVEEMQYMI
SWFPLQVATAMN*P*N*QVLISTRQKVKKMHNE
VLQNKVGKPREKQQNLKANTPL*PSTTPENVSNL
QEYLECICFHE*KEEKENGCAALQEPAHYHVKN
EGRGCGCRQTFPYLCH*QWLKSCGLCLGVIFVW
ILSLDHMTKCL*RVAPT*MMILPVASGPSQCQRI
*LCLIAKG*LNPRV*ISLAQVFTQ*KKDPESTV
FSITYLCVTAVLFTLFCIVQYICSALPPSLIAY
EKQNDVHYCEFLYHSFLKGLSFHFSFPYCGGVHR
IEHPFLKHSLSPCSLYVDELIKSNRFIKTPLLY
YRDI*KYPLM*ISPEFSLFGVCTDWNSICQICF
ILKWRTSPT*YIYIYIF*FMRILDNWKGRKEKPR
SY*GLEIFCSMESNFSQCCMILFKFGGQLIFTK
LNQVEKVISLQSCGHQSQK*SPGVVFSCLFSAL
SDPNVIMHFLMFVNFY**LV*IAF*YNNDYH*KL
TKFSLILCLMASAVF*HRASYMESFCELCNPSG
QYYEIICQW**IRNQ*YANGS*ITGQIA

Frame 1

AMQRKPPWLFSLNP*SSDAAAVKALIENQSTTS
RGSDRRAPFPGCLPWGRERPRSPRGWRGMW*SV
P
GRG*LHAAGAPRRERRLLLAGGARAGAS*PSTR
RARRDCGPWRRARGPALTRSGEVS*LSEKPWFP
QRSDF**KSEGHLQEKRDLV*SMN*RQEGFQS
V
PAMWIFGSND*CGNYICRFYCFRKNR*KKCNT*Y
PGFLCKWQQQ*ISLEISRS*YQQDRR*RRCTTK
FYRTKWGSPGRSSKI*KLTPHFDPRPHLKMSQI
SRSIWNAFVSMSEKRKKKMAVLHCRNLLIIMLKM
RAEAVAAGRLFPTSVISNG*NHVACVWASFLYG
SFHLII*RNAYRE*LRPR**FFL*HLAPHNVRG
FNCV*LRRVD*TPEFKYLWLKCSPSKRKIQKALF
LALRICVLLLCYLHCFVLYNIYAQHCPLL*LLM
KNKMMYITVNFYTTHF*KGCLFILVFHTVVVYT
G*NTLF*NTVFPLAHCMLMS*LSLTDSSRLHCFI
IETFENIH*CEYHLNSVCLVSAQTGIQSVKFVL
FSSGELLPHNIYIYIYFNL*EFWTIGKVEKKSQ
DHTKDWKYFVLWNQISHNAV*YYLNLEDNLSSLS
*IRWRK*SPCNHVDTNHKSKALVLCFHVFFQPS
QIQMLLCTF*CL*TFTNN*CELHSDTIMIIIRS
*QNSH*YCV*WPLLCFNIVLLIWKVFVSCVIPLV
SIMKSFVSGNK*GTSNMPMVHELLDK*

Frame 2

LCRESPPGSSLSIHNPAMLQL*KH**KINPQPR
GAAIVERRFQAAFPGVGSGPAPPVAGAECGDPS
RGGDDFMQPELRGGSGGCCWQVGRGPARADRAL
GGRGGTAARGGVRGDLR*LGPGKFPDFLRSPGFP
KEVISDRNLKVISKKKEI*YSQ*IKDKKVSNQ
S
LLCGYLVAMTDVETTYADFIASGRTGRRNAIHD
ILVSSASGNSNELALKLAGLDINKTEGEEDAQRS
STEQSGEAQGEAAKSES*HPTLTLDHT*KCLKS
PGVSGMHLFP*VKRGKRKWLCCIAGTCSLSC*K
*GQRLWLQADFSLPLSLAMVEIMWLVFGRHFCMD
PFT*SYDEMLIESSSDLDDDSSCSIWPLTMSED
LIVSNCEGLIEPQSLNISGSSVHPVKERSRKHC
F*HYVSVCYCCVIYTVLYCTIYMLSTAPFSDCL*
KTK*CTLL*IFIPLIFKRAVFSF*FSILWWCTQ
DRTPFFKTQSFPLLIVC**VD*V*QIHQDSIAL
L*RHLKISINVNIT*IQSVWCLHRLEFNLSNLFY
SQVENFSHIIYIYIYILIYENFGQLER*KRKAK
IILRTGNILFYGIKFLTMLYDTI*IWRTTYLH*
AESGGESNLLAIMWTPITKVKPWCCVFMSFFSPL
RSKCYYALFNVCKLLLIISVNCILIQ**LSLEA
NKILINTVFDGLCCVLTSCFLYGKFL*AV*SLW
SVL*NHLSVVINKEPVICQWFMNYWTNS

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