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Sequences

Sequence NM_002937

GCAGATGGTGCTGTCGACCAGTGTCAAGACCAAGTTTCATGGGTTCCTGGACGCTCAGCCAGGGGTAGTCTCTGAAGGGCCGCCTGGCAATTGGGAGCAG AAGCCAGTTTCCCGCCATCTGCTCTCCGTGGAGGCAGTGCTCTCGCGGCTGCTGCCCGTTGGGGTCCAGCTGAGGAAGGAGCGCGGATCCCAGGCTCGTT CTTTGCCTGGGCTGCCCCTGCGGCCCCTGGGGCGGGTGCTGCTGCGGCGCCAGCTCCAAGGGCGGATCCAGGCGGGAGGGGCCTCCTCGGAGAAGCGGGG CGCGGTCCCAACTACGCAGAGGCTGGCACGCCGACCCTCCACACCTCACCACGCCCCCATCTCCGTCCGTGTACACACACTCACACAAGGACGCCAACCC CACCTAGATGCAAAGCAGGATTCAAAAGAACATCTTTGCGTTTTCTACCGGCTCCCCATCATCGTACTAGGGAGGAAGAAGCGGGTGAGAAACAAAACTT CTTTCCATTGTCCTGCCCGTTTCTGCGGACTTGTTCTGAGGCCGAGGCACCTCTAAGATACTGATGGCTCTGCAGAGGACCCATTCATTGCTTCTGCTTT TGCTGCTGACCCTGCTGGGGCTGGGGCTGGTCCAGCCCTCCTATGGCCAGGATGGCATGTACCAGCGATTCCTGCGGCAACACGTGCACCCTGAGGAGAC AGGTGGCAGTGATCGCTACTGCAACTTGATGATGCAAAGACGGAAGATGACTTTGTATCACTGCAAGCGCTTCAACACCTTCATCCATGAAGATATCTGG AACATTCGTAGTATCTGCAGCACCACCAATATCCAATGCAAGAACGGCAAGATGAACTGCCATGAGGGTGTAGTGAAGGTCACAGATTGCAGGGACACAG GAAGTTCCAGGGCACCCAACTGCAGATATCGGGCCATAGCGAGCACTAGACGTGTTGTCATTGCCTGTGAGGGTAACCCACAGGTGCCTGTGCACTTTGA CGGTTAGATGCCACCATGTAGGGATTATCGCGAGTGGTTGACCTTACACTTACTCCTTAAATAGCAGTGAGTAATGCATTTGAGCTGTCCCAGGCTCTGT CTCCTCAGCTCATTTCCTACTCTTTTTCTCTATATAACTCATTCTATTAAATACATTGCACCAAAGAGATATGGAGACATAAACCTGTAATGAATGAGGC TGGGCTTTTCTGTAATAAGCTTCCTTTTATAATACTGGTCAGCTTAGCTCTCTCAGATCCTATCCTGTGGAATTTAGTTATTATGTGTATTTATGTAGTA TTTCAAACATTTCAAAATGCTTTCATCTATGTTTATCACATTTTAATACCACAGCACTTATAATGATGTCACTACATATAGAAGCTCAAAGTTAAGGGAT TTGCTGAAGACTGTAAAGTTAATGGAAGAATTGAGACAAAAATCCAGTGTAGCTGGCCACTTATCCAGGGCTTTTTCTACTTCATCACAAGGAATGTTTT GAAAGTGTCTGCTTTTTTTATCCTTAAAATTCACCTGTCAGGGAGGCATTAAAAATTTGGAAATGTATGCCAGCAAAATGTGAGCTCTGTATTTTTTGGC ATTCTTATGTTTGGGTTTAATAAGATTAAGAAAATGATACTGGGAATTTTCTTTTTCCTGAAACTTTGAATCACCCTAGTAAGTCAAAGTACTAAAAAAT GTACTAGATCATTAAGACTTATGTGCTCTTACTGATTGAAAGATTTTTTATGTTTTCCTTGTAATAAAGGACCTAAACCGAAGGTACCTGA

refseq_RNASE4.F2 (forward primer)
refseq_RNASE4.R2 (reverse primer)
Single exon skipping

Frame 0

ADGAVDQCQDQVSWVPGRSARGSL*RAAWQLGA EASFPPSALRGGSALAAAARWGPAEEGARIPGSF FAWAAPAAPGAGAAAAPAPRADPGGRGLLGEAG RGPNYAEAGTPTLHTSPRPHLRPCTHTHTRTPT PPRCKAGFKRTSLRFLPAPHHRTREEEAGEKQNF FPLSCPFLRTCSEAEAPLRY*WLCRGPIHCFCF CC*PCWGWGWSSPPMARMACTSDSCGNTCTLRR QVAVIATAT**CKDGR*LCITASASTPSSMKISG TFVVSAAPPISNARTAR*TAMRV**RSQIAGTQ EVPGHPTADIGP*RALDVLSLPVRVTHRCLCTL TVRCHHVGIIASG*PYTYSLNSSE*CI*AVPGSV SSAHFLLFFSI*LILLNTLHQRDMET*TCNE*G WAFL**ASFYNTGQLSSLRSYPVEFSYYVYLCS ISNISKCFHLCLSHFNTTALIMMSLHIEAQS*GI C*RL*S*WKN*DKNPV*LATYPGLFLLHHKECF ESVCFFYP*NSPVREALKIWKCMPAKCELCIFW HSYVWV**D*ENDTGNFLFPETLNHPSKSKY*KM Y*IIKTYVLLLIERFFMFSL**RT*TEGT*

Frame 1

QMVLSTSVKTKFHGFLDAQPGVVSEGPPGNWEQ KPVSRHLLSVEAVLSRLLPVGVQLRKERGSQAR SLPGLPLRPLGRVLLRRQLQGRIQAGGASSEKRG AVPTTQRLARRPSTPHHAPISVRVHTLTQGRQP HLDAKQDSKEHLCVFYRLPIIVLGRKKRVRNKT SFHCPARFCGLVLRPRHL*DTDGSAEDPFIASAF AADPAGAGAGPALLWPGWHVPAIPAATRAP*GD RWQ*SLLQLDDAKTEDDFVSLQALQHLHP*RYL EHS*YLQHHQYPMQERQDELP*GCSEGHRLQGHR KFQGTQLQISGHSEH*TCCHCL*G*PTGACAL* RLDATM*GLSRVVDLTLTP*IAVSNAFELSQAL SPQLISYSFSLYNSFY*IHCTKEIWRHKPVMNEA GLFCNKLPFIILVSLALSDPILWNLVIMCIYVV FQTFQNAFIYVYHILIPQHL**CHYI*KLKVKG FAEDCKVNGRIETKIQCSWPLIQGFFYFITRNVL KVSAFFILKIHLSGRH*KFGNVCQQNVSSVFFG ILMFGFNKIKKMILGIFFFLKL*ITLVSQSTKK CTRSLRLMCSY*LKDFLCFPCNKGPKPKVP

Frame 2

RWCCRPVSRPSFMGSWTLSQG*SLKGRLAIGSR SQFPAICSPWRQCSRGCCPLGSS*GRSADPRLV LCLGCPCGPWGGCCCGASSKGGSRREGPPRRSG ARSQLRRGWHADPPHLTTPPSPSVYTHSHKDANP T*MQSRIQKNIFAFSTGSPSSY*GGRSG*ETKL LSIVLPVSADLF*GRGTSKILMALQRTHSLLLL LLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPEET GGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDIW NIRSICSTTNIQCKNGKMNCHEGVVKVTDCRDT GSSRAPNCRYRAIASTRRVVIACEGNPQVPVHFD G*MPPCRDYREWLTLHLLLK*Q*VMHLSCPRLC LLSSFPTLFLYITHSIKYIAPKRYGDINL**MR LGFSVISFLL*YWSA*LSQILSCGI*LLCVFM*Y FKHFKMLSSMFITF*YHSTYNDVTTYRSSKLRD LLKTVKLMEELRQKSSVAGHLSRAFSTSSQGMF *KCLLFLSLKFTCQGGIKNLEMYASKM*ALYFLA FLCLGLIRLRK*YWEFSFS*NFESP**VKVLKN VLDH*DLCALTD*KIFYVFLVIKDLNRRYL

Sequence NM_194430

GCAGATGGTGCTGTCGACCAGTGTCAAGACCAAGTTTCATGGGTTCCTGGACGCTCAGCCAGGGGTAGTCTCTGAAGGGCCGCCTGGCAATTGGGAGCAG AAGCCAGTTTCCCGCCATCTGCTCTCCGTGGAGGCAGTGCTCTCGCGGCTGCTGCCCGTTGGGGTCCAGCTGAGGAAGGAGCGCGGATCCCAGGCTCGTT CTTTGCCTGGGCTGCCCCTGCGGCCCCTGGGGCGGGTGCTGCTGCGGCGCCAGCTCCAAGGGCGGATCCAGGCGGGAGGGGCCTCCTCGGAGAAGCGGGG CGCGGTCCCAACTACGCAGAGGCTGGCACGCCGACCCTCCACACCTCACCACGCCCCCATCTCCGTCCGTGTACACACACTCACACAAGGACGCCAACCC CACCTAGATGCAAAGCAGGATTCAAAAGAACATCTTTGCGTTTTCTACCGGCTCCCCATCATCGTACTAGGGAGGAAGAAGCGGGTGAGAAACAAAACTT CTTTCCATTGTCCTGCCCGTTTCTGCGGACTTGTTCTGAGGCCGAGGAGCCTGTGTTGGAAGAGATGGTGATGGGCCTGGGCGTTTTGTTGTTGGTCTTC GTGCTGGGTCTGGGTCTGACCCCACCGACCCTGGCTCAGGATAACTCCAGGCACCTCTAAGATACTGATGGCTCTGCAGAGGACCCATTCATTGCTTCTG CTTTTGCTGCTGACCCTGCTGGGGCTGGGGCTGGTCCAGCCCTCCTATGGCCAGGATGGCATGTACCAGCGATTCCTGCGGCAACACGTGCACCCTGAGG AGACAGGTGGCAGTGATCGCTACTGCAACTTGATGATGCAAAGACGGAAGATGACTTTGTATCACTGCAAGCGCTTCAACACCTTCATCCATGAAGATAT CTGGAACATTCGTAGTATCTGCAGCACCACCAATATCCAATGCAAGAACGGCAAGATGAACTGCCATGAGGGTGTAGTGAAGGTCACAGATTGCAGGGAC ACAGGAAGTTCCAGGGCACCCAACTGCAGATATCGGGCCATAGCGAGCACTAGACGTGTTGTCATTGCCTGTGAGGGTAACCCACAGGTGCCTGTGCACT TTGACGGTTAGATGCCACCATGTAGGGATTATCGCGAGTGGTTGACCTTACACTTACTCCTTAAATAGCAGTGAGTAATGCATTTGAGCTGTCCCAGGCT CTGTCTCCTCAGCTCATTTCCTACTCTTTTTCTCTATATAACTCATTCTATTAAATACATTGCACCAAAGAGATATGGAGACATAAACCTGTAATGAATG AGGCTGGGCTTTTCTGTAATAAGCTTCCTTTTATAATACTGGTCAGCTTAGCTCTCTCAGATCCTATCCTGTGGAATTTAGTTATTATGTGTATTTATGT AGTATTTCAAACATTTCAAAATGCTTTCATCTATGTTTATCACATTTTAATACCACAGCACTTATAATGATGTCACTACATATAGAAGCTCAAAGTTAAG GGATTTGCTGAAGACTGTAAAGTTAATGGAAGAATTGAGACAAAAATCCAGTGTAGCTGGCCACTTATCCAGGGCTTTTTCTACTTCATCACAAGGAATG TTTTGAAAGTGTCTGCTTTTTTTATCCTTAAAATTCACCTGTCAGGGAGGCATTAAAAATTTGGAAATGTATGCCAGCAAAATGTGAGCTCTGTATTTTT TGGCATTCTTATGTTTGGGTTTAATAAGATTAAGAAAATGATACTGGGAATTTTCTTTTTCCTGAAACTTTGAATCACCCTAGTAAGTCAAAGTACTAAA AAATGTACTAGATCATTAAGACTTATGTGCTCTTACTGATTGAAAGATTTTTTATGTTTTCCTTGTAATAAAGGACCTAAACCGAAGGTACCTGA

refseq_RNASE4.F2 (forward primer)
refseq_RNASE4.R2 (reverse primer)
Single exon skipping

Frame 0

ADGAVDQCQDQVSWVPGRSARGSL*RAAWQLGA EASFPPSALRGGSALAAAARWGPAEEGARIPGSF FAWAAPAAPGAGAAAAPAPRADPGGRGLLGEAG RGPNYAEAGTPTLHTSPRPHLRPCTHTHTRTPT PPRCKAGFKRTSLRFLPAPHHRTREEEAGEKQNF FPLSCPFLRTCSEAEEPVLEEMVMGLGVLLLVF VLGLGLTPPTLAQDNSRHL*DTDGSAEDPFIAS AFAADPAGAGAGPALLWPGWHVPAIPAATRAP*G DRWQ*SLLQLDDAKTEDDFVSLQALQHLHP*RY LEHS*YLQHHQYPMQERQDELP*GCSEGHRLQG HRKFQGTQLQISGHSEH*TCCHCL*G*PTGACAL *RLDATM*GLSRVVDLTLTP*IAVSNAFELSQA LSPQLISYSFSLYNSFY*IHCTKEIWRHKPVMN EAGLFCNKLPFIILVSLALSDPILWNLVIMCIYV VFQTFQNAFIYVYHILIPQHL**CHYI*KLKVK GFAEDCKVNGRIETKIQCSWPLIQGFFYFITRN VLKVSAFFILKIHLSGRH*KFGNVCQQNVSSVFF GILMFGFNKIKKMILGIFFFLKL*ITLVSQSTK KCTRSLRLMCSY*LKDFLCFPCNKGPKPKVP

Frame 1

QMVLSTSVKTKFHGFLDAQPGVVSEGPPGNWEQ KPVSRHLLSVEAVLSRLLPVGVQLRKERGSQAR SLPGLPLRPLGRVLLRRQLQGRIQAGGASSEKRG AVPTTQRLARRPSTPHHAPISVRVHTLTQGRQP HLDAKQDSKEHLCVFYRLPIIVLGRKKRVRNKT SFHCPARFCGLVLRPRSLCWKRW*WAWAFCCWSS CWVWV*PHRPWLRITPGTSKILMALQRTHSLLL LLLLTLLGLGLVQPSYGQDGMYQRFLRQHVHPE ETGGSDRYCNLMMQRRKMTLYHCKRFNTFIHEDI WNIRSICSTTNIQCKNGKMNCHEGVVKVTDCRD TGSSRAPNCRYRAIASTRRVVIACEGNPQVPVH FDG*MPPCRDYREWLTLHLLLK*Q*VMHLSCPRL CLLSSFPTLFLYITHSIKYIAPKRYGDINL**M RLGFSVISFLL*YWSA*LSQILSCGI*LLCVFM *YFKHFKMLSSMFITF*YHSTYNDVTTYRSSKLR DLLKTVKLMEELRQKSSVAGHLSRAFSTSSQGM F*KCLLFLSLKFTCQGGIKNLEMYASKM*ALYF LAFLCLGLIRLRK*YWEFSFS*NFESP**VKVLK NVLDH*DLCALTD*KIFYVFLVIKDLNRRYL

Frame 2

RWCCRPVSRPSFMGSWTLSQG*SLKGRLAIGSR SQFPAICSPWRQCSRGCCPLGSS*GRSADPRLV LCLGCPCGPWGGCCCGASSKGGSRREGPPRRSG ARSQLRRGWHADPPHLTTPPSPSVYTHSHKDANP T*MQSRIQKNIFAFSTGSPSSY*GGRSG*ETKL LSIVLPVSADLF*GRGACVGRDGDGPGRFVVGL RAGSGSDPTDPGSG*LQAPLRY*WLCRGPIHCFC FCC*PCWGWGWSSPPMARMACTSDSCGNTCTLR RQVAVIATAT**CKDGR*LCITASASTPSSMKI SGTFVVSAAPPISNARTAR*TAMRV**RSQIAGT QEVPGHPTADIGP*RALDVLSLPVRVTHRCLCT LTVRCHHVGIIASG*PYTYSLNSSE*CI*AVPG SVSSAHFLLFFSI*LILLNTLHQRDMET*TCNE* GWAFL**ASFYNTGQLSSLRSYPVEFSYYVYLC SISNISKCFHLCLSHFNTTALIMMSLHIEAQS* GIC*RL*S*WKN*DKNPV*LATYPGLFLLHHKEC FESVCFFYP*NSPVREALKIWKCMPAKCELCIF WHSYVWV**D*ENDTGNFLFPETLNHPSKSKY* KMY*IIKTYVLLLIERFFMFSL**RT*TEGT*