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Sequences

Sequence NM_138618

ATCGCTCCCTCAAGCCCTCAAGTAGGTGTTGGAGAGAGGGGTGATGCCTGGTGCTGGTGGAACCCCTGCACAGAGACGGACACAGGATGAGCTCTAAGTA CCCGCGGTCTGTCCGGCGCTGCCTGCCCCTCTGCGCCCTAACACTGGAAGCAGCTCTCATTCTCCTCTTCTATTTTTTTACCCACTATGACGCTTCCTTA GAGGATCAAAAGGGGCTCGTGGCATCCTATCAAGTCGGCCAAGATCTGACCGTGATGGCGGCCCTTGGCTTGGGCTTCCTCACCTCAAATTTCCGGAGAC ACAGCTGGAGCAGTGTGGCCTTCAACCTCTTCATGCTGGCGCTTGGTGTGCAGTGGGCAATCCTGCTGGACGGCTTCCTGAGCCAGTTCCCTCCTGGGAA GGTGGTCATCACACTGTTCAGTATTCGGCTGGCCACCATGAGTGCTATGTCGGTGCTGATCTCAGCGGGTGCTGTCTTGGGGAAGGTCAACTTGGCGCAG TTGGTGGTGATGGTGCTGGTGGAGGTGACAGCTTTAGGCACCCTGAGGATGGTCATCAGTAATATCTTCAACACAGACTACCACATGAACCTGAGGCACT TCTACGTGTTCGCAGCCTATTTTGGGCTGACTGTGGCCTGGTGCCTGCCAAAGCCTCTACCCAAGGGAACGGAGGATAATGATCAGAGAGCAACGATACC CAGTTTGTCTGCCATGCTGGGCGCCCTCTTCTTGTGGATGTTCTGGCCAAGTGTCAACTCTGCTCTGCTGAGAAGTCCAATCCAAAGGAAGAATGCCATG TTCAACACCTACTATGCTCTAGCAGTCAGTGTGGTGACAGCCATCTCAGGGTCATCCTTGGCTCACCCCCAAAGGAAGATCAGCATGACTTATGTGCACA GTGCGGTGTTGGCAGGAGGCGTGGCTGTGGGTACCTCGTGTCACCTGATCCCTTCTCCGTGGCTTGCCATGGTGCTGGGTCTTGTGGCTGGGCTGATCTC CATCGGGGGAGCCAAGTGCCTGCCGGATTGGCTTCCAGGTCCTCCTCAGCATTGGGGAACTCAGCTTGGCCATCGTGATAGCTCTCACGTCTGGTCTCCT GACAGGTTTGCTCCTAAATCTCAAAATATGGAAAGCACCTCATGTGGCTAAATATTTTGATGACCAAGTTTTCTGGAAGTTTCCTCATTTGGCTGTTGGA TTTTAAGCAAAAGCATCCAAGAAAAACAAGGCCTGTTCAAAAACAAGACAACTTCCTCTCACTGTTGCCTGCATTTGTACGTGAGAAACGCTCATGACAG CAAAGTCTCCTTATGTATAATGAAACAAGGTCAGAGACAGATTTGATATTAAAAAATTAAAGACTAAAAACTTAGTTTAAGAGTCAATTTAATAAGTTTA AAATAAATGTTTAGTTTCATTAGGATGATGCTATCAATATTTTCTTGGTTACAGACACATTATTAAAGTTTTGGGTTAATTTTA

refseq_RHCE.F3 (forward primer)
refseq_RHCE.R3 (reverse primer)
Single exon skipping

Frame 0

IAPSSPQVGVGERGDAWCWWNPCTETDTG*ALS TRGLSGAACPSAP*HWKQLSFSSSIFLPTMTLP* RIKRGSWHPIKSAKI*P*WRPLAWASSPQISGD TAGAVWPSTSSCWRLVCSGQSCWTAS*ASSLLG RWSSHCSVFGWPP*VLCRC*SQRVLSWGRSTWRS WW*WCWWR*QL*AP*GWSSVISSTQTTT*T*GT STCSQPILG*LWPGACQSLYPRERRIMIREQRY PVCLPCWAPSSCGCSGQVSTLLC*EVQSKGRMPC STPTML*QSVW*QPSQGHPWLTPKGRSA*LMCT VRCWQEAWLWVPRVT*SLLRGLPWCWVLWLG*S PSGEPSACRIGFQVLLSIGELSLAIVIALTSGLL TGLLLNLKIWKAPHVAKYFDDQVFWKFPHLAVG F*AKASKKNKACSKTRQLPLTVACICT*ETLMT AKSPYV**NKVRDRFDIKKLKTKNLV*ESI**V* NKCLVSLG*CYQYFLGYRHIIKVLG*F

Frame 1

SLPQALK*VLERGVMPGAGGTPAQRRTQDEL*V PAVCPALPAPLRPNTGSSSHSPLLFFYPL*RFL RGSKGARGILSSRPRSDRDGGPWLGLPHLKFPET QLEQCGLQPLHAGAWCAVGNPAGRLPEPVPSWE GGHHTVQYSAGHHECYVGADLSGCCLGEGQLGA VGGDGAGGGDSFRHPEDGHQ*YLQHRLPHEPEAL LRVRSLFWADCGLVPAKASTQGNGG**SESNDT QFVCHAGRPLLVDVLAKCQLCSAEKSNPKEECH VQHLLCSSSQCGDSHLRVILGSPPKEDQHDLCAQ CGVGRRRGCGYLVSPDPFSVACHGAGSCGWADL HRGSQVPAGLASRSSSALGNSAWPS**LSRLVS *QVCS*ISKYGKHLMWLNILMTKFSGSFLIWLLD FKQKHPRKTRPVQKQDNFLSLLPAFVREKRS*Q QSLLMYNETRSETDLILKN*RLKT*FKSQFNKF KINV*FH*DDAINIFLVTDTLLKFWVNF

Frame 2

RSLKPSSRCWREG*CLVLVEPLHRDGHRMSSKY PRSVRRCLPLCALTLEAALILLFYFFTHYDASL EDQKGLVASYQVGQDLTVMAALGLGFLTSNFRR HSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGK VVITLFSIRLATMSAMSVLISAGAVLGKVNLAQ LVVMVLVEVTALGTLRMVISNIFNTDYHMNLRH FYVFAAYFGLTVAWCLPKPLPKGTEDNDQRATIP SLSAMLGALFLWMFWPSVNSALLRSPIQRKNAM FNTYYALAVSVVTAISGSSLAHPQRKISMTYVH SAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLIS IGGAKCLPDWLPGPPQHWGTQLGHRDSSHVWSP DRFAPKSQNMESTSCG*IF**PSFLEVSSFGCW ILSKSIQEKQGLFKNKTTSSHCCLHLYVRNAHDS KVSLCIMKQGQRQI*Y*KIKD*KLSLRVNLISL K*MFSFIRMMLSIFSWLQTHY*SFGLIL

Sequence NM_020485

ATCGCTCCCTCAAGCCCTCAAGTAGGTGTTGGAGAGAGGGGTGATGCCTGGTGCTGGTGGAACCCCTGCACAGAGACGGACACAGGATGAGCTCTAAGTA CCCGCGGTCTGTCCGGCGCTGCCTGCCCCTCTGCGCCCTAACACTGGAAGCAGCTCTCATTCTCCTCTTCTATTTTTTTACCCACTATGACGCTTCCTTA GAGGATCAAAAGGGGCTCGTGGCATCCTATCAAGTCGGCCAAGATCTGACCGTGATGGCGGCCCTTGGCTTGGGCTTCCTCACCTCAAATTTCCGGAGAC ACAGCTGGAGCAGTGTGGCCTTCAACCTCTTCATGCTGGCGCTTGGTGTGCAGTGGGCAATCCTGCTGGACGGCTTCCTGAGCCAGTTCCCTCCTGGGAA GGTGGTCATCACACTGTTCAGTATTCGGCTGGCCACCATGAGTGCTATGTCGGTGCTGATCTCAGCGGGTGCTGTCTTGGGGAAGGTCAACTTGGCGCAG TTGGTGGTGATGGTGCTGGTGGAGGTGACAGCTTTAGGCACCCTGAGGATGGTCATCAGTAATATCTTCAACACAGACTACCACATGAACCTGAGGCACT TCTACGTGTTCGCAGCCTATTTTGGGCTGACTGTGGCCTGGTGCCTGCCAAAGCCTCTACCCAAGGGAACGGAGGATAATGATCAGAGAGCAACGATACC CAGTTTGTCTGCCATGCTGGGCGCCCTCTTCTTGTGGATGTTCTGGCCAAGTGTCAACTCTGCTCTGCTGAGAAGTCCAATCCAAAGGAAGAATGCCATG TTCAACACCTACTATGCTCTAGCAGTCAGTGTGGTGACAGCCATCTCAGGGTCATCCTTGGCTCACCCCCAAAGGAAGATCAGCATGACTTATGTGCACA GTGCGGTGTTGGCAGGAGGCGTGGCTGTGGGTACCTCGTGTCACCTGATCCCTTCTCCGTGGCTTGCCATGGTGCTGGGTCTTGTGGCTGGGCTGATCTC CATCGGGGGAGCCAAGTGCCTGCCGGTGTGTTGTAACCGAGTGCTGGGGATTCACCACATCTCCGTCATGCACTCCATCTTCAGCTTGCTGGGTCTGCTT GGAGAGATCACCTACATTGTGCTGCTGGTGCTTCATACTGTCTGGAACGGCAATGGCATGATTGGCTTCCAGGTCCTCCTCAGCATTGGGGAACTCAGCT TGGCCATCGTGATAGCTCTCACGTCTGGTCTCCTGACAGGTTTGCTCCTAAATCTCAAAATATGGAAAGCACCTCATGTGGCTAAATATTTTGATGACCA AGTTTTCTGGAAGTTTCCTCATTTGGCTGTTGGATTTTAAGCAAAAGCATCCAAGAAAAACAAGGCCTGTTCAAAAACAAGACAACTTCCTCTCACTGTT GCCTGCATTTGTACGTGAGAAACGCTCATGACAGCAAAGTCTCCTTATGTATAATGAAACAAGGTCAGAGACAGATTTGATATTAAAAAATTAAAGACTA AAAACTTAGTTTAAGAGTCAATTTAATAAGTTTAAAATAAATGTTTAGTTTCATTAGGATGATGCTATCAATATTTTCTTGGTTACAGACACATTATTAA AGTTTTGGGTTAATTTTA

refseq_RHCE.F3 (forward primer)
refseq_RHCE.R3 (reverse primer)
Single exon skipping

Frame 0

IAPSSPQVGVGERGDAWCWWNPCTETDTG*ALS TRGLSGAACPSAP*HWKQLSFSSSIFLPTMTLP* RIKRGSWHPIKSAKI*P*WRPLAWASSPQISGD TAGAVWPSTSSCWRLVCSGQSCWTAS*ASSLLG RWSSHCSVFGWPP*VLCRC*SQRVLSWGRSTWRS WW*WCWWR*QL*AP*GWSSVISSTQTTT*T*GT STCSQPILG*LWPGACQSLYPRERRIMIREQRY PVCLPCWAPSSCGCSGQVSTLLC*EVQSKGRMPC STPTML*QSVW*QPSQGHPWLTPKGRSA*LMCT VRCWQEAWLWVPRVT*SLLRGLPWCWVLWLG*S PSGEPSACRCVVTECWGFTTSPSCTPSSACWVCL ERSPTLCCWCFILSGTAMA*LASRSSSALGNSA WPS**LSRLVS*QVCS*ISKYGKHLMWLNILMT KFSGSFLIWLLDFKQKHPRKTRPVQKQDNFLSLL PAFVREKRS*QQSLLMYNETRSETDLILKN*RL KT*FKSQFNKFKINV*FH*DDAINIFLVTDTLL KFWVNF

Frame 1

SLPQALK*VLERGVMPGAGGTPAQRRTQDEL*V PAVCPALPAPLRPNTGSSSHSPLLFFYPL*RFL RGSKGARGILSSRPRSDRDGGPWLGLPHLKFPET QLEQCGLQPLHAGAWCAVGNPAGRLPEPVPSWE GGHHTVQYSAGHHECYVGADLSGCCLGEGQLGA VGGDGAGGGDSFRHPEDGHQ*YLQHRLPHEPEAL LRVRSLFWADCGLVPAKASTQGNGG**SESNDT QFVCHAGRPLLVDVLAKCQLCSAEKSNPKEECH VQHLLCSSSQCGDSHLRVILGSPPKEDQHDLCAQ CGVGRRRGCGYLVSPDPFSVACHGAGSCGWADL HRGSQVPAGVL*PSAGDSPHLRHALHLQLAGSA WRDHLHCAAGASYCLERQWHDWLPGPPQHWGTQL GHRDSSHVWSPDRFAPKSQNMESTSCG*IF**P SFLEVSSFGCWILSKSIQEKQGLFKNKTTSSHC CLHLYVRNAHDSKVSLCIMKQGQRQI*Y*KIKD* KLSLRVNLISLK*MFSFIRMMLSIFSWLQTHY* SFGLIL

Frame 2

RSLKPSSRCWREG*CLVLVEPLHRDGHRMSSKY PRSVRRCLPLCALTLEAALILLFYFFTHYDASL EDQKGLVASYQVGQDLTVMAALGLGFLTSNFRR HSWSSVAFNLFMLALGVQWAILLDGFLSQFPPGK VVITLFSIRLATMSAMSVLISAGAVLGKVNLAQ LVVMVLVEVTALGTLRMVISNIFNTDYHMNLRH FYVFAAYFGLTVAWCLPKPLPKGTEDNDQRATIP SLSAMLGALFLWMFWPSVNSALLRSPIQRKNAM FNTYYALAVSVVTAISGSSLAHPQRKISMTYVH SAVLAGGVAVGTSCHLIPSPWLAMVLGLVAGLIS IGGAKCLPVCCNRVLGIHHISVMHSIFSLLGLL GEITYIVLLVLHTVWNGNGMIGFQVLLSIGELS LAIVIALTSGLLTGLLLNLKIWKAPHVAKYFDDQ VFWKFPHLAVGF*AKASKKNKACSKTRQLPLTV ACICT*ETLMTAKSPYV**NKVRDRFDIKKLKT KNLV*ESI**V*NKCLVSLG*CYQYFLGYRHIIK VLG*F