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Sequences

Sequence XM_932949

AAACCTTGGCTTCAGCCCGGCCGCCGCCAGGCGTTGGCATCGCCGGGGAGAGCCTTCCGGACTCCGGGCGGCGGCTGGCTGGGGGCGCGTTCCGAGGCGC
CCTCAGGCAGGGCGCGGGGGCAGAGCCTCGCCTGGGTTCTGGAGGCTGCGGGGCCATCGCTCCAGATGCGAAAGCCATGGAGTTGAGCTGCAGCGAAGCA
CCTCTTTACGGGCAGATGATGATCTATGCGAAGTTTGACAAAAATGTGTATCTTCCTGAAGATGCTGAGTTTTACTTTACTTATGACGGATCTCATCAGC
GACATGTCATGATTGCAGAGCGCATCGAGGATAACGTTCTCCAGTCCAGCGTCCCAGGCCATGGGCTTCAGGAGACGGTGACGGTATCTGTGTGCCTCTG
CTCGGAAGGTTACTCTCCGGTGACCATGGGCTCTGGCTCAGTGACCTACGTGGACAACATGGCTTGCAGGCTGGCTCGTCTGCTGGTGACGCAGGCCAAT
CGCCTCACAGCCTGCAGCCACCAGACCCTGCTGACCCCATTTGCCTTGACGGCAGGAGCACTGCCTGCCTTGGATGAGGAGCTCGTGCTGGCTCTGACCC
ATCTGGAATTGCCTCTAGAGTGGACTGTGTTGGGAAGTTCTTCACTTGAAGTATCTTCTCACAGAGAATCTCTTCTACACCTGGCTATGAGATGGGGCCT
GGCTAAACTTTCCCAGTTCTTCTTGTGTCTCCCGGGGGGAGTCCAGGCCTTGGCTTTACCCAACGAAGAGGGTGCCACACCATTAGACTTAGCTTTACGT
GAAGGACACTCCAAGCTGGTGGAAGACGTCACAAATTTTCAGGGCAGATGGTCCCCAAGCTTCTCCCGAGTGCAGCTCAGTGAAGAAGCCTCCTTGCATT
ACATTCACTCATCGGAAACGCTGACCCTGACCCTGAACCACACAGCCGAGCATTTGTTGGAGGCAGATATTAAACTCTTCCGGAAATACTTTTGGGATAG
AGCCTTTCTTGTCAAGGCCTTTGAGCCAGAAGCCAGGCCAGAGGAAAGAACAGCTATGCCCTCCAGCGGTGCAGAAACTGAAGAAGAGATTAAGAATTCA
GTGTCCAGCAGATCAGCAGCTGAAAAGGAAGATATAAAGCGTGTCAAAAGCCTGGTGGTTCAACACAATGAACATGAAGACCAGCACAGCCTAGATTTGG
ATCGCTCCTTCGATATCCTAAAAAAATCCAAGCCGCCCTCGACATTGCTTGCTGCAGGCCGGCTTTCAGACATGCTGAATGGAGGTGATGAAGTCTACGC
TAACTGTATGGTGATTGATCAGGTTGGTGATTTGGATATCAGCTATATTAATATAGAGGGAATCACTGCCACTACCAGCCCTGAATCCAGAGGTTGCACT
CTGTGGCCTCAGAGCAGCAAACACACCCTTCCTACAGAAACCAGTCCCAGTGTGTACCCACTTAGTGAAAATGTCGAAGGGACAGCACACACTGAAGCCC
AGCAGTCCTTCATGTCACCATCAAGTTCGTGTGCTTCCAACTTGAATCTTTCTTTTGGTTGGCATGGATTTGAAAAGGAACAAAGTCATCTAAAGAAAAG
AAGTTCTAGCCTTGATGCCTTGGACGCCGACAGTGAAGGGGAAGGGCATTCTGAGCCATCCCACATCTGTTACACTCCAGGGTCTCAGAGCTCCTCAAGA
ACTGGGATTCCTAGTGGGGATGAATTGGACTCTTTTGAGACTAACACTGAACCGGATTTTAATATCTCCAGGGCTGAATCCCTTCCTCTATCAAGTAATC
TACAGTCGAAGGAATCACTGCTTTCTGGAGTTCGCTCACGTTCTTATTCTTGCTCATCACCCAAAATTTCTTTAGGAAAAACTCGTTTGGTGCGTGAATT
AACAGTATGCAGTTCAAGTGAAGAGCAAAGAGCTTACAGCTTATCGGAGCCACCAAGAGAAAACAGAATTCAGGAAGAAGAATGGGATAAATACATCATA
CCTGCCAAATCAGAGTCTGAAAAATATAAAGTGAGTCGAACTTTCAGTTTCCTCATGAATAGGATGACTAGCCCTCGGAATAAATCAAAGACAAAAAGCA
AGGATGCCAAAGATAAAGAGAAGCTGAATCGACATCAGTTTGCCCCAGGAACATTCTCTGGGGTTCTGCAGTGTTTGGTTTGTGATAAAACACTCCTGGG
GAAAGAGTCACTGCAGTGTTCTAACTGTAATGCAAATGTGCACAAAGGTTGTAAAGATGCTGCGCCTGCATGCACCAAGAAATTCCAAGAGAAATATAAC
AAGAACAAACCACAGACCATCCTTGGAAATTCTTCATTTAGAGACATCCCACAGCCTGGTCTCTCCTTGCACCCTTCTTCCTCCGTGCCTGTTGGATTGC
CGACTGGAAGGAGGGAGACTGTGGGACAGGTCCATCCATTGTCCAGAAGTGTTCCAGGCACCACCTTGGAAAGCTTCAGGAGGTCAGCCACATCCTTGGA
GTCTGAGAGTGACCATAACAGCTGCAGAAGCAGGTCTCATTCTGATGAGCTGCTACAGTCCATGGGCTCTTCTCCCTCTACAGAGTCTTTCATAATGGAA
GATGTTGTGGATTCTTCTCTGTGGAGTGACCTCAGCAGTGATGCCCAGGAGTTTGAAGCAGAATCTTGGAGTCTTGTGGTGGATCCCTCATTTTGTAATA
GGCAGGAGAAGGATGTCATCAAAAGACAGGATGTCATTTTTGAGCTAATGCAAACAGAGATGCATCACATCCAGACCCTGTTCATCATGTCTGAGATCTT
CAGGAAAGGCATGAAAGAGGAGCTGCAGCTGGACCACAGCACCGTGGATAAAATTTTCCCCTGTTTAGATGAGTTGCTTGAAATCCACAGGCATTTCTTC
TACAGTATGAAGGAACGAAGGCAGGAATCCTGTGCTGGCAGCGACAGGAATTTTGTGATCGACCGAATTGGAGATATTTTGGTACAACAGTTTTCAGAAG
AAAATGCAAGTAAAATGAAGAAAATATATGGAGAATTCTGTTGCCATCATAAAGAAGCTGTTAACCTCTTTAAAGAACTCCAGCAGAATAAAAAGTTTCA
GAATTTTATTAAGCTCCGAAATAGTAATCTTTTGGCTCGACGCCGAGGAATTCCAGAATGCATTCTGTTGGTCACTCAGCGTATTACAAAATACCCTGTC
TTGGTGGAAAGGATATTGCAGTACACAAAGGAAAGAACTGAGGAACATAAAGACTTACGCAAAGCGCTTTGCTTAATTAAAGACATGATTGCAACAGTGG
ATTTAAAAGTCAATGAATATGAGAAAAACCAAAAATGGCTTGAGATCCTAAATAAGATTGAAAACAAAACATACACGAAGCTCAAAAATGGACATGTGTT
TAGGAAGCAGGCACTGATGAGTGAAGAAAGGACTCTGTTATATGATGGCCTTGTTTACTGGAAAACTGCTACAGGTCGTTTCAAAGATATCCTAGCTCTA
CTTCTAACTGATGTGCTGCTCTTTTTACAAGAAAAAGACCAGAAATACATCTTTGCAGCCGTTGATCAGAAGCCATCAGTTATTTCCCTTCAAAAGCTTA
TTGCTAGAGAAGTTGCTAATGAGGAGAGAGGAATGTTTCTGATCAGTGCTTCATCTGCTGGTCCTGAGATGTATGAAATTCACACCAATTCCAAGGAGGA
ACGCAATAACTGGATGAGACGGATCCAGCAGGCTGTAGAAAGTTGTCCTGAAGAAAAAGGGGGAAGGACAAGTGAATCTGATGAAGACAAGAGGAAAGCT
GAAGCCAGAGTGGCCAAAATTCAGCAATGTCAAGAAATACTCACTAACCAAGACCAACAAATTTGTGCGTATTTGGAGGAGAAGCTGCATATCTATGCTG
AACTTGGAGAACTGAGCGGATTTGAGGACGTCCATCTAGAGCCCCACCTCCTTATTAAACCTGACCCAGGCGAGCCTCCCCAGGCAGCCTCATTACTGGC
AGCAGCACTGAAAGAAGCATTAGTCACAGGAGGGAGAGAAGGAAGAGGCTGTTCGGATGTGGATCCCGGGATCCAGGGTGTGGTAACCGACTTGGCCGTC
TCTGATGCAGGGGAGAAGGTGGAATGTAGAAATTTTCCAGGTTCTTCACAATCAGAGATTATACAAGCCATACAGAATTTAACCCGTCTCTTATACAGCC
TTCAGGCCGCCTTGACCATTCAGGACAGCCACATTGAGATCCACAGGCTGGTTCTCCAGCAGCAGGAGGGCCTGTCTCTCGGCCACTCTATCCTCCGAGG
CGGCCCCTTGCAGGACCAGAAGTCTCGCGACGCGGACAGGCAGCATGAGGAGCTGGCCAATGTGCACCAGCTTCAGCACCAGCTCCAGCAGGAGCAGCGG
CGCTGGCTGCGCAGGTGTGAGCAGCAGCAGCGGGCGCAGGCGACCAGGGAGAGCTGGCTGCAGGAGCGGGAGCGGGAGTGCCAGTCGCAGGAGGAGCTGC
TGCTGCGGAGCCGGGGCGAGCTGGACCTCCAGCTCCAGGAGTACCAGCACAGCCTGGAGCGGCTGAGGGAGGGCCAGCGCCTGGTGGAGAGGGAGCAGGC
GAGGATGCGGGCCCAGCAGAGCCTGCTGGGCCACTGGAAGCACGGCCGGCAGAGGAGCCTGCCCGCGGTGCTCCTTCCGGGTGGCCCCGAGGTAATGGAA
CTTAATCGATCTGAGAGTTTATGTCATGAAAACTCATTCTTCATCAATGAAGCTTTAGTACAAATGTCATTTAACACTTTCAACAAACTGAATCCATCAG
TTATCCATCAGGATGCCACTTACCCTACAACTCAATCTCATTCTGACTTGGTGAGGACTAGTGAACATCAAGTAGACCTCAAGGTGGACCCTTCTCAGCC
TTCGAATGTCAGTCACAAACTGTGGACAGCCGCTGGTTCCGGCCATCAGATACTTCCTTTCCATGAAAGCAGCAAGGATTCTTGTAAAAATGGCTCCAGT
ATGACAAAGTGCAGTTGTACGTTGACATCTCCCCCGGGACTGTGGACTGGAACCACATCTACTTTGAAAGATTTGGACACCTCCCACACTGAGTCCCCAA
CCCCCCATGACTCAAATTCACACCGCCCTCAACTGCAGGCGTTTATAACAGAAGCAAAGCTAAATCTACCGACAAGGACAATGACCAGACAAGATGGGGA
AACTGGAGATGGAGCCAAAGAAAATATTGTTTACCTCTAATTGTGTTGTCATTTTTCCAAACAAAACAAAACACTGGCACTTTTGGGAGAAACTTTTTGT
CTCCATTCCTTATGTATGTGTGATTGTCTGTGTCCAAATTGCTTTAAGAATAATATTTAATATTTCCTGGAAGCTCATTTTTTTGGCATGAGTCTAATTA
AATTATTGAAAGCCACCCTGTTTGTATAATCTTTAACTTATCAAATCTAATTTCAGATTTCTGGAGGAGAAACTAACTTGAATAAGCAGGACTATTTTAA
AAGTTGTTTTGACGCTAGAGTAAAATTCCATGTCACATTTTCTACCCAATCATCTGGATTTCAAGATTCCTTTTAAGATCTCAATGAAGCAATTTGGATT
TAAAGAGTGGTATTCACAAGGGGTGAACTTTCACAGTCAGGGCAGTTGCCTCAGTGCCCACATAGGCAGAGGAGGATGTGGGAAAGGGTTTTTCTCAGCT
AGTTTTTGTGTGCTCATTTCTTCTGGGAGCATTAAAAGTGGTGATCTGTTACAGTCACTATTCAACTGGGCACGTGTTGTGATTGGTCAGTCACTGAGCC
AGGGATACAGTCCGGACTTGCTTAGTACCTAAGCCTAATGCTGGTGGGGTTTCAAGACATGGTTCAGCATCATCTTTTAACAAGGCCCAGAGGCCCAGAG
CCCCCATCAAGTCATTTTGATGTAAATAGTGAACTTTGTTAGAGCCCTCACTTCTATCAATCAGCTGTCCTGTCCCTGCCAGCACCTGGAGCACCAACTA
CCACTCCCTGGAAAGAACCCTTCCCTGCAGTTTTTTAAGGACAAAACTGCCCACTCCTCATTAAGTTTGCTGCCTGGATACACTTTTCCACAAAGGAAAA
CTGGCATATCCTGCCTTCCGAGTAGTATGGGTCTCTGTGTGAGAAACCAGGAGATATTTTCATCTTGTTCGGAAATACTTGTATGTATTTTGGTGTCAAT
AAATATCTTGTACCTCATTATTTTACTTTGTAATTTTAACATTATGTGTAGGACCATAGTAAAACATTCATTTCACACAGACATCTAATCTCACCTCGTG
AAAAGTGAAAATAAAGGAAAACTATTAGATTCATCCAAAAATGCAACACCTACTGGGAGTGAGATGTGATAGGAACAGAAAAAAAAAAAAAAAAATCACC
CGGATCTCAATAGTTTTTTCTCCCTACTTAAAGTTGTTAAGTTGGATATCTACATTGTGTTTTTACTTAGGCAAGTCCAATCCTAATTTTTTTAAAAGCC
CCTTTTGGGGGCAGTCTTTTTCTGACTTTAGCTGGCTATTTTTGTAACAATTACATTAAAAATTCGGTGACTGA
  • refseq_RGNEF.F1 (forward primer)
  • refseq_RGNEF.R1 (reverse primer)
  • Single exon skipping

Frame 0

KPWLQPGRRQALASPGRAFRTPGGGWLGARSEA
PSGRARGQSLAWVLEAAGPSLQMRKPWS*AAAKH
LFTGR**SMRSLTKMCIFLKMLSFTLLMTDLIS
DMS*LQSASRITFSSPASQAMGFRRR*RYLCAS
ARKVTLR*PWALAQ*PTWTTWLAGWLVCW*RRPI
ASQPAATRPC*PHLP*RQEHCLPWMRSSCWL*P
IWNCL*SGLCWEVLHLKYLLTENLFYTWL*DGA
WLNFPSSSCVSRGESRPWLYPTKRVPHH*T*LYV
KDTPSWWKTSQIFRADGPQASPECSSVKKPPCI
TFTHRKR*P*P*TTQPSICWRQILNSSGNTFGI
EPFLSRPLSQKPGQRKEQLCPPAVQKLKKRLRIQ
CPADQQLKRKI*SVSKAWWFNTMNMKTSTA*IW
IAPSIS*KNPSRPRHCLLQAGFQTC*MEVMKST
LTVW*LIRLVIWISAILI*RESLPLPALNPEVAL
CGLRAANTPFLQKPVPVCTHLVKMSKGQHTLKP
SSPSCHHQVRVLPT*IFLLVGMDLKRNKVI*RK
EVLALMPWTPTVKGKGILSHPTSVTLQGLRAPQE
LGFLVGMNWTLLRLTLNRILISPGLNPFLYQVI
YSRRNHCFLEFAHVLILAHHPKFL*EKLVWCVN
*QYAVQVKSKELTAYRSHQEKTEFRKKNGINTSY
LPNQSLKNIK*VELSVSS*IG*LALGINQRQKA
RMPKIKRS*IDISLPQEHSLGFCSVWFVIKHSW
GKSHCSVLTVMQMCTKVVKMLRLHAPRNSKRNIT
RTNHRPSLEILHLETSHSLVSPCTLLPPCLLDC
RLEGGRLWDRSIHCPEVFQAPPWKASGGQPHPW
SLRVTITAAEAGLILMSCYSPWALLPLQSLS*WK
MLWILLCGVTSAVMPRSLKQNLGVLWWIPHFVI
GRRRMSSKDRMSFLS*CKQRCITSRPCSSCLRS
SGKA*KRSCSWTTAPWIKFSPV*MSCLKSTGISS
TV*RNEGRNPVLAATGIL*STELEIFWYNSFQK
KMQVK*RKYMENSVAIIKKLLTSLKNSSRIKSF
RILLSSEIVIFWLDAEEFQNAFCWSLSVLQNTLS
WWKGYCSTQRKELRNIKTYAKRFA*LKT*LQQW
I*KSMNMRKTKNGLRS*IRLKTKHTRSSKMDMC
LGSRH**VKKGLCYMMALFTGKLLQVVSKIS*LY
F*LMCCSFYKKKTRNTSLQPLIRSHQLFPFKSL
LLEKLLMRREECF*SVLHLLVLRCMKFTPIPRR
NAITG*DGSSRL*KVVLKKKGEGQVNLMKTRGKL
KPEWPKFSNVKKYSLTKTNKFVRIWRRSCISML
NLEN*ADLRTSI*SPTSLLNLTQASLPRQPHYW
QQH*KKH*SQEGEKEEAVRMWIPGSRVW*PTWPS
LMQGRRWNVEIFQVLHNQRLYKPYRI*PVSYTA
FRPP*PFRTATLRSTGWFSSSRRACLSATLSSE
AAPCRTRSLATRTGSMRSWPMCTSFSTSSSRSSG
AGCAGVSSSSGRRRPGRAGCRSGSGSASRRRSC
CCGAGASWTSSSRSTSTAWSG*GRASAWWRGSR
RGCGPSRACWATGSTAGRGACPRCSFRVAPR*WN
LIDLRVYVMKTHSSSMKL*YKCHLTLSTN*IHQ
LSIRMPLTLQLNLILTW*GLVNIK*TSRWTLLS
LRMSVTNCGQPLVPAIRYFLSMKAARILVKMAPV
*QSAVVR*HLPRDCGLEPHLL*KIWTPPTLSPQ
PPMTQIHTALNCRRL*QKQS*IYRQGQ*PDKMG
KLEMEPKKILFTSNCVVIFPNKTKHWHFWEKLFV
SIPYVCVIVCVQIALRIIFNISWKLIFLA*V*L
NY*KPPCLYNL*LIKSNFRFLEEKLT*ISRTIL
KVVLTLE*NSMSHFLPNHLDFKIPFKISMKQFGF
KEWYSQGVNFHSQGSCLSAHIGRGGCGKGFFSA
SFCVLISSGSIKSGDLLQSLFNWARVVIGQSLS
QGYSPDLLST*A*CWWGFKTWFSIIF*QGPEAQS
PHQVILM*IVNFVRALTSINQLSCPCQHLEHQL
PLPGKNPSLQFFKDKTAHSSLSLLPGYTFPQRK
TGISCLPSSMGLCVRNQEIFSSCSEILVCILVSI
NILYLIILLCNFNIMCRTIVKHSFHTDI*SHLV
KSENKGKLLDSSKNATPTGSEM**EQKKKKKNH
PDLNSFFSLLKVVKLDIYIVFLLRQVQS*FF*KP
LLGAVFF*L*LAIFVTITLKIR*L

Frame 1

NLGFSPAAARRWHRRGEPSGLRAAAGWGRVPRR
PQAGRGGRASPGFWRLRGHRSRCESHGVELQRS
TSLRADDDLCEV*QKCVSS*RC*VLLYL*RISSA
TCHDCRAHRG*RSPVQRPRPWASGDGDGICVPL
LGRLLSGDHGLWLSDLRGQHGLQAGSSAGDAGQ
SPHSLQPPDPADPICLDGRSTACLG*GARAGSDP
SGIASRVDCVGKFFT*SIFSQRISSTPGYEMGP
G*TFPVLLVSPGGSPGLGFTQRRGCHTIRLSFT
*RTLQAGGRRHKFSGQMVPKLLPSAAQ*RSLLAL
HSLIGNADPDPEPHSRAFVGGRY*TLPEILLG*
SLSCQGL*ARSQARGKNSYALQRCRN*RRD*EF
SVQQISS*KGRYKACQKPGGSTQ*T*RPAQPRFG
SLLRYPKKIQAALDIACCRPAFRHAEWR**SLR
*LYGD*SGW*FGYQLY*YRGNHCHYQP*IQRLH
SVASEQQTHPSYRNQSQCVPT**KCRRDSTH*SP
AVLHVTIKFVCFQLESFFWLAWI*KGTKSSKEK
KF*P*CLGRRQ*RGRAF*AIPHLLHSRVSELLK
NWDS*WG*IGLF*D*H*TGF*YLQG*IPSSIK*S
TVEGITAFWSSLTFLFLLITQNFFRKNSFGA*I
NSMQFK*RAKSLQLIGATKRKQNSGRRMG*IHH
TCQIRV*KI*SESNFQFPHE*DD*PSE*IKDKKQ
GCQR*REAESTSVCPRNILWGSAVFGL**NTPG
ERVTAVF*L*CKCAQRL*RCCACMHQEIPREI*
QEQTTDHPWKFFI*RHPTAWSLLAPFFLRACWIA
DWKEGDCGTGPSIVQKCSRHHLGKLQEVSHILG
V*E*P*QLQKQVSF**AATVHGLFSLYRVFHNG
RCCGFFSVE*PQQ*CPGV*SRILESCGGSLIL**
AGEGCHQKTGCHF*ANANRDASHPDPVHHV*DL
QERHERGAAAGPQHRG*NFPLFR*VA*NPQAFL
LQYEGTKAGILCWQRQEFCDRPNWRYFGTTVFRR
KCK*NEENIWRILLPS*RSC*PL*RTPAE*KVS
EFY*APK**SFGSTPRNSRMHSVGHSAYYKIPC
LGGKDIAVHKGKN*GT*RLTQSALLN*RHDCNSG
FKSQ*I*EKPKMA*DPK*D*KQNIHEAQKWTCV
*EAGTDE*RKDSVI*WPCLLENCYRSFQRYPSS
TSN*CAALFTRKRPEIHLCSR*SEAISYFPSKAY
C*RSC**GERNVSDQCFICWS*DV*NSHQFQGG
TQ*LDETDPAGCRKLS*RKRGKDK*I**RQEES
*SQSGQNSAMSRNTH*PRPTNLCVFGGEAAYLC*
TWRTERI*GRPSRAPPPY*T*PRRASPGSLITG
SSTERSISHRRERRKRLFGCGSRDPGCGNRLGR
L*CRGEGGM*KFSRFFTIRDYTSHTEFNPSLIQP
SGRLDHSGQPH*DPQAGSPAAGGPVSRPLYPPR
RPLAGPEVSRRGQAA*GAGQCAPASAPAPAGAA
ALAAQV*AAAAGAGDQGELAAGAGAGVPVAGGAA
AAEPGRAGPPAPGVPAQPGAAEGGPAPGGEGAG
EDAGPAEPAGPLEARPAEEPARGAPSGWPRGNG
T*SI*EFMS*KLILHQ*SFSTNVI*HFQQTESIS
YPSGCHLPYNSISF*LGED**TSSRPQGGPFSA
FECQSQTVDSRWFRPSDTSFP*KQQGFL*KWLQ
YDKVQLYVDISPGTVDWNHIYFERFGHLPH*VPN
PP*LKFTPPSTAGVYNRSKAKSTDKDNDQTRWG
NWRWSQRKYCLPLIVLSFFQTKQNTGTFGRNFL
SPFLMYV*LSVSKLL*E*YLIFPGSSFFWHESN*
IIESHPVCIIFNLSNLISDFWRRN*LE*AGLF*
KLF*R*SKIPCHIFYPIIWISRFLLRSQ*SNLD
LKSGIHKG*TFTVRAVASVPT*AEEDVGKGFSQL
VFVCSFLLGALKVVICYSHYSTGHVL*LVSH*A
RDTVRTCLVPKPNAGGVSRHGSASSFNKAQRPR
APIKSF*CK**TLLEPSLLSISCPVPASTWSTNY
HSLERTLPCSFLRTKLPTPH*VCCLDTLFHKGK
LAYPAFRVVWVSV*ETRRYFHLVRKYLYVFWCQ
*ISCTSLFYFVILTLCVGP**NIHFTQTSNLTS*
KVKIKENY*IHPKMQHLLGVRCDRNRKKKKKIT
RISIVFSPYLKLLSWISTLCFYLGKSNPNFFKS
PFWGQSFSDFSWLFL*QLH*KFGD*

Frame 2

TLASARPPPGVGIAGESLPDSGRRLAGGAFRGA
LRQGAGAEPRLGSGGCGAIAPDAKAMELSCSEA
PLYGQMMIYAKFDKNVYLPEDAEFYFTYDGSHQ
RHVMIAERIEDNVLQSSVPGHGLQETVTVSVCLC
SEGYSPVTMGSGSVTYVDNMACRLARLLVTQAN
RLTACSHQTLLTPFALTAGALPALDEELVLALT
HLELPLEWTVLGSSSLEVSSHRESLLHLAMRWGL
AKLSQFFLCLPGGVQALALPNEEGATPLDLALR
EGHSKLVEDVTNFQGRWSPSFSRVQLSEEASLH
YIHSSETLTLTLNHTAEHLLEADIKLFRKYFWDR
AFLVKAFEPEARPEERTAMPSSGAETEEEIKNS
VSSRSAAEKEDIKRVKSLVVQHNEHEDQHSLDL
DRSFDILKKSKPPSTLLAAGRLSDMLNGGDEVYA
NCMVIDQVGDLDISYINIEGITATTSPESRGCT
LWPQSSKHTLPTETSPSVYPLSENVEGTAHTEA
QQSFMSPSSSCASNLNLSFGWHGFEKEQSHLKKR
SSSLDALDADSEGEGHSEPSHICYTPGSQSSSR
TGIPSGDELDSFETNTEPDFNISRAESLPLSSN
LQSKESLLSGVRSRSYSCSSPKISLGKTRLVREL
TVCSSSEEQRAYSLSEPPRENRIQEEEWDKYII
PAKSESEKYKVSRTFSFLMNRMTSPRNKSKTKS
KDAKDKEKLNRHQFAPGTFSGVLQCLVCDKTLLG
KESLQCSNCNANVHKGCKDAAPACTKKFQEKYN
KNKPQTILGNSSFRDIPQPGLSLHPSSSVPVGL
PTGRRETVGQVHPLSRSVPGTTLESFRRSATSLE
SESDHNSCRSRSHSDELLQSMGSSPSTESFIME
DVVDSSLWSDLSSDAQEFEAESWSLVVDPSFCN
RQEKDVIKRQDVIFELMQTEMHHIQTLFIMSEIF
RKGMKEELQLDHSTVDKIFPCLDELLEIHRHFF
YSMKERRQESCAGSDRNFVIDRIGDILVQQFSE
ENASKMKKIYGEFCCHHKEAVNLFKELQQNKKFQ
NFIKLRNSNLLARRRGIPECILLVTQRITKYPV
LVERILQYTKERTEEHKDLRKALCLIKDMIATV
DLKVNEYEKNQKWLEILNKIENKTYTKLKNGHVF
RKQALMSEERTLLYDGLVYWKTATGRFKDILAL
LLTDVLLFLQEKDQKYIFAAVDQKPSVISLQKL
IAREVANEERGMFLISASSAGPEMYEIHTNSKEE
RNNWMRRIQQAVESCPEEKGGRTSESDEDKRKA
EARVAKIQQCQEILTNQDQQICAYLEEKLHIYA
ELGELSGFEDVHLEPHLLIKPDPGEPPQAASLLA
AALKEALVTGGREGRGCSDVDPGIQGVVTDLAV
SDAGEKVECRNFPGSSQSEIIQAIQNLTRLLYS
LQAALTIQDSHIEIHRLVLQQQEGLSLGHSILRG
GPLQDQKSRDADRQHEELANVHQLQHQLQQEQR
RWLRRCEQQQRAQATRESWLQERERECQSQEEL
LLRSRGELDLQLQEYQHSLERLREGQRLVEREQA
RMRAQQSLLGHWKHGRQRSLPAVLLPGGPEVME
LNRSESLCHENSFFINEALVQMSFNTFNKLNPS
VIHQDATYPTTQSHSDLVRTSEHQVDLKVDPSQP
SNVSHKLWTAAGSGHQILPFHESSKDSCKNGSS
MTKCSCTLTSPPGLWTGTTSTLKDLDTSHTESP
TPHDSNSHRPQLQAFITEAKLNLPTRTMTRQDGE
TGDGAKENIVYL*LCCHFSKQNKTLALLGETFC
LHSLCMCDCLCPNCFKNNI*YFLEAHFFGMSLI
KLLKATLFV*SLTYQI*FQISGGETNLNKQDYFK
SCFDARVKFHVTFSTQSSGFQDSF*DLNEAIWI
*RVVFTRGELSQSGQLPQCPHRQRRMWERVFLS
*FLCAHFFWEH*KW*SVTVTIQLGTCCDWSVTEP
GIQSGLA*YLSLMLVGFQDMVQHHLLTRPRGPE
PPSSHFDVNSELC*SPHFYQSAVLSLPAPGAPT
TTPWKEPFPAVF*GQNCPLLIKFAAWIHFSTKEN
WHILPSE*YGSLCEKPGDIFILFGNTCMYFGVN
KYLVPHYFTL*F*HYV*DHSKTFISHRHLISPR
EK*K*RKTIRFIQKCNTYWE*DVIGTEKKKKKSP
GSQ*FFLPT*SC*VGYLHCVFT*ASPILIFLKA
PFGGSLFLTLAGYFCNNYIKNSVT

Sequence XM_371755

AAACCTTGGCTTCAGCCCGGCCGCCGCCAGGCGTTGGCATCGCCGGGGAGAGCCTTCCGGACTCCGGGCGGCGGCTGGCTGGGGGCGCGTTCCGAGGCGC
CCTCAGGCAGGGCGCGGGGGCAGAGCCTCGCCTGGGTTCTGGAGGCTGCGGGGCCATCGCTCCAGATGCGAAAGCCATGGAGTTGAGCTGCAGCGAAGCA
CCTCTTTACGGGCAGATGATGATCTATGCGAAGTTTGACAAAAATGTGTATCTTCCTGAAGATGCTGAGTTTTACTTTACTTATGACGGATCTCATCAGC
GACATGTCATGATTGCAGAGCGCATCGAGGATAACGTTCTCCAGTCCAGCGTCCCAGGCCATGGGCTTCAGGAGACGGTGACGGTATCTGTGTGCCTCTG
CTCGGAAGGTTACTCTCCGGTGACCATGGGCTCTGGCTCAGTGACCTACGTGGACAACATGGCTTGCAGGCTGGCTCGTCTGCTGGTGACGCAGGCCAAT
CGCCTCACAGCCTGCAGCCACCAGACCCTGCTGACCCCATTTGCCTTGACGGCAGGAGCACTGCCTGCCTTGGATGAGGAGCTCGTGCTGGCTCTGACCC
ATCTGGAATTGCCTCTAGAGTGGACTGTGTTGGGAAGTTCTTCACTTGAAGTATCTTCTCACAGAGAATCTCTTCTACACCTGGCTATGAGATGGGGCCT
GGCTAAACTTTCCCAGTTCTTCTTGTGTCTCCCGGGGGGAGTCCAGGCCTTGGCTTTACCCAACGAAGAGGGTGCCACACCATTAGACTTAGCTTTACGT
GAAGGACACTCCAAGCTGGTGGAAGACGTCACAAATTTTCAGGGCAGATGGTCCCCAAGCTTCTCCCGAGTGCAGCTCAGTGAAGAAGCCTCCTTGCATT
ACATTCACTCATCGGAAACGCTGACCCTGACCCTGAACCACACAGCCGAGCATTTGTTGGAGGCAGATATTAAACTCTTCCGGAAATACTTTTGGGATAG
AGCCTTTCTTGTCAAGGCCTTTGAGCCAGAAGCCAGGCCAGAGGAAAGAACAGCTATGCCCTCCAGCGGTGCAGAAACTGAAGAAGAGATTAAGAATTCA
GTGTCCAGCAGATCAGCAGCTGAAAAGGAAGATATAAAGCGTGTCAAAAGCCTGGTGGTTCAACACAATGAACATGAAGACCAGCACAGCCTAGATTTGG
ATCGCTCCTTCGATATCCTAAAAAAATCCAAGCCGCCCTCGACATTGCTTGCTGCAGGCCGGCTTTCAGACATGCTGAATGGAGGTGATGAAGTCTACGC
TAACTGTATGGTGATTGATCAGGTTGGTGATTTGGATATCAGCTATATTAATATAGAGGGAATCACTGCCACTACCAGCCCTGAATCCAGAGGTTGCACT
CTGTGGCCTCAGAGCAGCAAACACACCCTTCCTACAGAAACCAGTCCCAGTGTGTACCCACTTAGTGAAAATGTCGAAGGGACAGCACACACTGAAGCCC
AGCAGTCCTTCATGTCACCATCAAGTTCGTGTGCTTCCAACTTGAATCTTTCTTTTGGTTGGCATGGATTTGAAAAGGAACAAAGTCATCTAAAGAAAAG
AAGTTCTAGCCTTGATGCCTTGGACGCCGACAGTGAAGGGGAAGGGCATTCTGAGCCATCCCACATCTGTTACACTCCAGGGTCTCAGAGCTCCTCAAGA
ACTGGGATTCCTAGTGGGGATGAATTGGACTCTTTTGAGACTAACACTGAACCGGATTTTAATATCTCCAGGGCTGAATCCCTTCCTCTATCAAGTAATC
TACAGTCGAAGGAATCACTGCTTTCTGGAGTTCGCTCACGTTCTTATTCTTGCTCATCACCCAAAATTTCTTTAGGAAAAACTCGTTTGGTGCGTGAATT
AACAGTATGCAGTTCAAGTGAAGAGCAAAGAGCTTACAGCTTATCGGAGCCACCAAGAGAAAACAGAATTCAGGAAGAAGAATGGGATAAATACATCATA
CCTGCCAAATCAGAGTCTGAAAAATATAAAGTGAGTCGAACTTTCAGTTTCCTCATGAATAGGATGACTAGCCCTCGGAATAAATCAAAGACAAAAAGCA
AGGATGCCAAAGATAAAGAGAAGCTGAATCGACATCAGTTTGCCCCAGGAACATTCTCTGGGGTTCTGCAGTGTTTGGTTTGTGATAAAACACTCCTGGG
GAAAGAGTCACTGCAGTGTTCTAACTGTAATGCAAATGTGCACAAAGGTTGTAAAGATGCTGCGCCTGCATGCACCAAGAAATTCCAAGAGAAATATAAC
AAGAACAAACCACAGACCATCCTTGGAAATTCTTCATTTAGAGACATCCCACAGCCTGGTCTCTCCTTGCACCCTTCTTCCTCCGTGCCTGTTGGATTGC
CGACTGGAAGGAGGGAGACTGTGGGACAGGTCCATCCATTGTCCAGAAGTGTTCCAGGCACCACCTTGGAAAGCTTCAGGAGGTCAGCCACATCCTTGGA
GTCTGAGAGTGACCATAACAGCTGCAGAAGCAGGTCTCATTCTGATGAGCTGCTACAGTCCATGGGCTCTTCTCCCTCTACAGAGTCTTTCATAATGGAA
GATGTTGTGGATTCTTCTCTGTGGAGTGACCTCAGCAGTGATGCCCAGGAGTTTGAAGCAGAATCTTGGAGTCTTGTGGTGGATCCCTCATTTTGTAATA
GGCAGGAGAAGGATGTCATCAAAAGACAGGATGTCATTTTTGAGCTAATGCAAACAGAGATGCATCACATCCAGACCCTGTTCATCATGTCTGAGATCTT
CAGGAAAGGCATGAAAGAGGAGCTGCAGCTGGACCACAGCACCGTGGATAAAATTTTCCCCTGTTTAGATGAGTTGCTTGAAATCCACAGGCATTTCTTC
TACAGTATGAAGGAACGAAGGCAGGAATCCTGTGCTGGCAGCGACAGGAATTTTGTGATCGACCGAATTGGAGATATTTTGGTACAACAGTTTTCAGAAG
AAAATGCAAGTAAAATGAAGAAAATATATGGAGAATTCTGTTGCCATCATAAAGAAGCTGTTAACCTCTTTAAAGAACTCCAGCAGAATAAAAAGTTTCA
GAATTTTATTAAGCTCCGAAATAGTAATCTTTTGGCTCGACGCCGAGGAATTCCAGAATGCATTCTGTTGGTCACTCAGCGTATTACAAAATACCCTGTC
TTGGTGGAAAGGATATTGCAGTACACAAAGGAAAGAACTGAGGAACATAAAGACTTACGCAAAGCGCTTTGCTTAATTAAAGACATGATTGCAACAGTGG
ATTTAAAAGTCAATGAATATGAGAAAAACCAAAAATGGCTTGAGATCCTAAATAAGATTGAAAACAAAACATACACGAAGCTCAAAAATGGACATGTGTT
TAGGAAGCAGGCACTGATGAGTGAAGAAAGGACTCTGTTATATGATGGCCTTGTTTACTGGAAAACTGCTACAGGTCGTTTCAAAGATATCCTAGCTCTA
CTTCTAACTGATGTGCTGCTCTTTTTACAAGAAAAAGACCAGAAATACATCTTTGCAGCCGTTGATCAGAAGCCATCAGTTATTTCCCTTCAAAAGCTTA
TTGCTAGAGAAGTTGCTAATGAGGAGAGAGGAATGTTTCTGATCAGTGCTTCATCTGCTGGTCCTGAGATGTATGAAATTCACACCAATTCCAAGGAGGA
ACGCAATAACTGGATGAGACGGATCCAGCAGGCTGTAGAAAGTTGTCCTGAAGAAAAAGGGGGAAGGACAAGTGAATCTGATGAAGACAAGAGGAAAGCT
GAAGCCAGAGTGGCCAAAATTCAGCAATGTCAAGAAATACTCACTAACCAAGACCAACAAATTTGTGCGTATTTGGAGGAGAAGCTGCATATCTATGCTG
AACTTGGAGAACTGAGCGGATTTGAGGACGTCCATCTAGAGCCCCACCTCCTTATTAAACCTGACCCAGGCGAGCCTCCCCAGGCAGCCTCATTACTGGC
AGCAGCACTGAAAGAAGCTGAGAGCCTACAAGTTGCAGTGAAGGCCTCACAGATGGGCGCCGTGAGTCAATCATGTGAGGACAGTTGTGGAGACTCTGTC
TTGGCGGACACACTCAGTTCTCATGATGTACCAGGATCACCGACTGCCT
CATTAGTCACAGGAGGGAGAGAAGGAAGAGGCTGTTCGGATGTGGATCCCG
GGATCCAGGGTGTGGTAACCGACTTGGCCGTCTCTGATGCAGGGGAGAAGGTGGAATGTAGAAATTTTCCAGGTTCTTCACAATCAGAGATTATACAAGC
CATACAGAATTTAACCCGTCTCTTATACAGCCTTCAGGCCGCCTTGACCATTCAGGACAGCCACATTGAGATCCACAGGCTGGTTCTCCAGCAGCAGGAG
GGCCTGTCTCTCGGCCACTCTATCCTCCGAGGCGGCCCCTTGCAGGACCAGAAGTCTCGCGACGCGGACAGGCAGCATGAGGAGCTGGCCAATGTGCACC
AGCTTCAGCACCAGCTCCAGCAGGAGCAGCGGCGCTGGCTGCGCAGGTGTGAGCAGCAGCAGCGGGCGCAGGCGACCAGGGAGAGCTGGCTGCAGGAGCG
GGAGCGGGAGTGCCAGTCGCAGGAGGAGCTGCTGCTGCGGAGCCGGGGCGAGCTGGACCTCCAGCTCCAGGAGTACCAGCACAGCCTGGAGCGGCTGAGG
GAGGGCCAGCGCCTGGTGGAGAGGGAGCAGGCGAGGATGCGGGCCCAGCAGAGCCTGCTGGGCCACTGGAAGCACGGCCGGCAGAGGAGCCTGCCCGCGG
TGCTCCTTCCGGGTGGCCCCGAGGTAATGGAACTTAATCGATCTGAGAGTTTATGTCATGAAAACTCATTCTTCATCAATGAAGCTTTAGTACAAATGTC
ATTTAACACTTTCAACAAACTGAATCCATCAGTTATCCATCAGGATGCCACTTACCCTACAACTCAATCTCATTCTGACTTGGTGAGGACTAGTGAACAT
CAAGTAGACCTCAAGGTGGACCCTTCTCAGCCTTCGAATGTCAGTCACAAACTGTGGACAGCCGCTGGTTCCGGCCATCAGATACTTCCTTTCCATGAAA
GCAGCAAGGATTCTTGTAAAAATGGTAATTAACACTTTAAACATCATCTGTATAGTTTGAACAAGAAGTTGTCCCTCTGAATGGTTGGCTCTTGTGTAGA
GTGAATCAAAGTCCTCCCTAGCATGGGAATAAATCGGTACTGATGAGCTGGA
  • refseq_RGNEF.F1 (forward primer)
  • refseq_RGNEF.R1 (reverse primer)
  • Single exon skipping

Frame 0

KPWLQPGRRQALASPGRAFRTPGGGWLGARSEA
PSGRARGQSLAWVLEAAGPSLQMRKPWS*AAAKH
LFTGR**SMRSLTKMCIFLKMLSFTLLMTDLIS
DMS*LQSASRITFSSPASQAMGFRRR*RYLCAS
ARKVTLR*PWALAQ*PTWTTWLAGWLVCW*RRPI
ASQPAATRPC*PHLP*RQEHCLPWMRSSCWL*P
IWNCL*SGLCWEVLHLKYLLTENLFYTWL*DGA
WLNFPSSSCVSRGESRPWLYPTKRVPHH*T*LYV
KDTPSWWKTSQIFRADGPQASPECSSVKKPPCI
TFTHRKR*P*P*TTQPSICWRQILNSSGNTFGI
EPFLSRPLSQKPGQRKEQLCPPAVQKLKKRLRIQ
CPADQQLKRKI*SVSKAWWFNTMNMKTSTA*IW
IAPSIS*KNPSRPRHCLLQAGFQTC*MEVMKST
LTVW*LIRLVIWISAILI*RESLPLPALNPEVAL
CGLRAANTPFLQKPVPVCTHLVKMSKGQHTLKP
SSPSCHHQVRVLPT*IFLLVGMDLKRNKVI*RK
EVLALMPWTPTVKGKGILSHPTSVTLQGLRAPQE
LGFLVGMNWTLLRLTLNRILISPGLNPFLYQVI
YSRRNHCFLEFAHVLILAHHPKFL*EKLVWCVN
*QYAVQVKSKELTAYRSHQEKTEFRKKNGINTSY
LPNQSLKNIK*VELSVSS*IG*LALGINQRQKA
RMPKIKRS*IDISLPQEHSLGFCSVWFVIKHSW
GKSHCSVLTVMQMCTKVVKMLRLHAPRNSKRNIT
RTNHRPSLEILHLETSHSLVSPCTLLPPCLLDC
RLEGGRLWDRSIHCPEVFQAPPWKASGGQPHPW
SLRVTITAAEAGLILMSCYSPWALLPLQSLS*WK
MLWILLCGVTSAVMPRSLKQNLGVLWWIPHFVI
GRRRMSSKDRMSFLS*CKQRCITSRPCSSCLRS
SGKA*KRSCSWTTAPWIKFSPV*MSCLKSTGISS
TV*RNEGRNPVLAATGIL*STELEIFWYNSFQK
KMQVK*RKYMENSVAIIKKLLTSLKNSSRIKSF
RILLSSEIVIFWLDAEEFQNAFCWSLSVLQNTLS
WWKGYCSTQRKELRNIKTYAKRFA*LKT*LQQW
I*KSMNMRKTKNGLRS*IRLKTKHTRSSKMDMC
LGSRH**VKKGLCYMMALFTGKLLQVVSKIS*LY
F*LMCCSFYKKKTRNTSLQPLIRSHQLFPFKSL
LLEKLLMRREECF*SVLHLLVLRCMKFTPIPRR
NAITG*DGSSRL*KVVLKKKGEGQVNLMKTRGKL
KPEWPKFSNVKKYSLTKTNKFVRIWRRSCISML
NLEN*ADLRTSI*SPTSLLNLTQASLPRQPHYW
QQH*KKLRAYKLQ*RPHRWAP*VNHVRTVVETLS
WRTHSVLMMYQDHRLP
H*SQEGEKEEAVRMWIP
GSRVW*PTWPSLMQGRRWNVEIFQVLHNQRLYK
PYRI*PVSYTAFRPP*PFRTATLRSTGWFSSSRR
ACLSATLSSEAAPCRTRSLATRTGSMRSWPMCT
SFSTSSSRSSGAGCAGVSSSSGRRRPGRAGCRS
GSGSASRRRSCCCGAGASWTSSSRSTSTAWSG*G
RASAWWRGSRRGCGPSRACWATGSTAGRGACPR
CSFRVAPR*WNLIDLRVYVMKTHSSSMKL*YKC
HLTLSTN*IHQLSIRMPLTLQLNLILTW*GLVNI
K*TSRWTLLSLRMSVTNCGQPLVPAIRYFLSMK
AARILVKMVINTLNIICIV*TRSCPSEWLALV*
SESKSSLAWE*IGTDEL

Frame 1

NLGFSPAAARRWHRRGEPSGLRAAAGWGRVPRR
PQAGRGGRASPGFWRLRGHRSRCESHGVELQRS
TSLRADDDLCEV*QKCVSS*RC*VLLYL*RISSA
TCHDCRAHRG*RSPVQRPRPWASGDGDGICVPL
LGRLLSGDHGLWLSDLRGQHGLQAGSSAGDAGQ
SPHSLQPPDPADPICLDGRSTACLG*GARAGSDP
SGIASRVDCVGKFFT*SIFSQRISSTPGYEMGP
G*TFPVLLVSPGGSPGLGFTQRRGCHTIRLSFT
*RTLQAGGRRHKFSGQMVPKLLPSAAQ*RSLLAL
HSLIGNADPDPEPHSRAFVGGRY*TLPEILLG*
SLSCQGL*ARSQARGKNSYALQRCRN*RRD*EF
SVQQISS*KGRYKACQKPGGSTQ*T*RPAQPRFG
SLLRYPKKIQAALDIACCRPAFRHAEWR**SLR
*LYGD*SGW*FGYQLY*YRGNHCHYQP*IQRLH
SVASEQQTHPSYRNQSQCVPT**KCRRDSTH*SP
AVLHVTIKFVCFQLESFFWLAWI*KGTKSSKEK
KF*P*CLGRRQ*RGRAF*AIPHLLHSRVSELLK
NWDS*WG*IGLF*D*H*TGF*YLQG*IPSSIK*S
TVEGITAFWSSLTFLFLLITQNFFRKNSFGA*I
NSMQFK*RAKSLQLIGATKRKQNSGRRMG*IHH
TCQIRV*KI*SESNFQFPHE*DD*PSE*IKDKKQ
GCQR*REAESTSVCPRNILWGSAVFGL**NTPG
ERVTAVF*L*CKCAQRL*RCCACMHQEIPREI*
QEQTTDHPWKFFI*RHPTAWSLLAPFFLRACWIA
DWKEGDCGTGPSIVQKCSRHHLGKLQEVSHILG
V*E*P*QLQKQVSF**AATVHGLFSLYRVFHNG
RCCGFFSVE*PQQ*CPGV*SRILESCGGSLIL**
AGEGCHQKTGCHF*ANANRDASHPDPVHHV*DL
QERHERGAAAGPQHRG*NFPLFR*VA*NPQAFL
LQYEGTKAGILCWQRQEFCDRPNWRYFGTTVFRR
KCK*NEENIWRILLPS*RSC*PL*RTPAE*KVS
EFY*APK**SFGSTPRNSRMHSVGHSAYYKIPC
LGGKDIAVHKGKN*GT*RLTQSALLN*RHDCNSG
FKSQ*I*EKPKMA*DPK*D*KQNIHEAQKWTCV
*EAGTDE*RKDSVI*WPCLLENCYRSFQRYPSS
TSN*CAALFTRKRPEIHLCSR*SEAISYFPSKAY
C*RSC**GERNVSDQCFICWS*DV*NSHQFQGG
TQ*LDETDPAGCRKLS*RKRGKDK*I**RQEES
*SQSGQNSAMSRNTH*PRPTNLCVFGGEAAYLC*
TWRTERI*GRPSRAPPPY*T*PRRASPGSLITG
SSTERS*EPTSCSEGLTDGRRESIM*GQLWRLC
LGGHTQFS*CTRITDCL
ISHRRERRKRLFGCGSR
DPGCGNRLGRL*CRGEGGM*KFSRFFTIRDYTS
HTEFNPSLIQPSGRLDHSGQPH*DPQAGSPAAG
GPVSRPLYPPRRPLAGPEVSRRGQAA*GAGQCAP
ASAPAPAGAAALAAQV*AAAAGAGDQGELAAGA
GAGVPVAGGAAAAEPGRAGPPAPGVPAQPGAAE
GGPAPGGEGAGEDAGPAEPAGPLEARPAEEPARG
APSGWPRGNGT*SI*EFMS*KLILHQ*SFSTNV
I*HFQQTESISYPSGCHLPYNSISF*LGED**T
SSRPQGGPFSAFECQSQTVDSRWFRPSDTSFP*K
QQGFL*KW*LTL*TSSV*FEQEVVPLNGWLLCR
VNQSPP*HGNKSVLMSW

Frame 2

TLASARPPPGVGIAGESLPDSGRRLAGGAFRGA
LRQGAGAEPRLGSGGCGAIAPDAKAMELSCSEA
PLYGQMMIYAKFDKNVYLPEDAEFYFTYDGSHQ
RHVMIAERIEDNVLQSSVPGHGLQETVTVSVCLC
SEGYSPVTMGSGSVTYVDNMACRLARLLVTQAN
RLTACSHQTLLTPFALTAGALPALDEELVLALT
HLELPLEWTVLGSSSLEVSSHRESLLHLAMRWGL
AKLSQFFLCLPGGVQALALPNEEGATPLDLALR
EGHSKLVEDVTNFQGRWSPSFSRVQLSEEASLH
YIHSSETLTLTLNHTAEHLLEADIKLFRKYFWDR
AFLVKAFEPEARPEERTAMPSSGAETEEEIKNS
VSSRSAAEKEDIKRVKSLVVQHNEHEDQHSLDL
DRSFDILKKSKPPSTLLAAGRLSDMLNGGDEVYA
NCMVIDQVGDLDISYINIEGITATTSPESRGCT
LWPQSSKHTLPTETSPSVYPLSENVEGTAHTEA
QQSFMSPSSSCASNLNLSFGWHGFEKEQSHLKKR
SSSLDALDADSEGEGHSEPSHICYTPGSQSSSR
TGIPSGDELDSFETNTEPDFNISRAESLPLSSN
LQSKESLLSGVRSRSYSCSSPKISLGKTRLVREL
TVCSSSEEQRAYSLSEPPRENRIQEEEWDKYII
PAKSESEKYKVSRTFSFLMNRMTSPRNKSKTKS
KDAKDKEKLNRHQFAPGTFSGVLQCLVCDKTLLG
KESLQCSNCNANVHKGCKDAAPACTKKFQEKYN
KNKPQTILGNSSFRDIPQPGLSLHPSSSVPVGL
PTGRRETVGQVHPLSRSVPGTTLESFRRSATSLE
SESDHNSCRSRSHSDELLQSMGSSPSTESFIME
DVVDSSLWSDLSSDAQEFEAESWSLVVDPSFCN
RQEKDVIKRQDVIFELMQTEMHHIQTLFIMSEIF
RKGMKEELQLDHSTVDKIFPCLDELLEIHRHFF
YSMKERRQESCAGSDRNFVIDRIGDILVQQFSE
ENASKMKKIYGEFCCHHKEAVNLFKELQQNKKFQ
NFIKLRNSNLLARRRGIPECILLVTQRITKYPV
LVERILQYTKERTEEHKDLRKALCLIKDMIATV
DLKVNEYEKNQKWLEILNKIENKTYTKLKNGHVF
RKQALMSEERTLLYDGLVYWKTATGRFKDILAL
LLTDVLLFLQEKDQKYIFAAVDQKPSVISLQKL
IAREVANEERGMFLISASSAGPEMYEIHTNSKEE
RNNWMRRIQQAVESCPEEKGGRTSESDEDKRKA
EARVAKIQQCQEILTNQDQQICAYLEEKLHIYA
ELGELSGFEDVHLEPHLLIKPDPGEPPQAASLLA
AALKEAESLQVAVKASQMGAVSQSCEDSCGDSV
LADTLSSHDVPGSPTA
SLVTGGREGRGCSDVDP
GIQGVVTDLAVSDAGEKVECRNFPGSSQSEIIQA
IQNLTRLLYSLQAALTIQDSHIEIHRLVLQQQE
GLSLGHSILRGGPLQDQKSRDADRQHEELANVH
QLQHQLQQEQRRWLRRCEQQQRAQATRESWLQER
ERECQSQEELLLRSRGELDLQLQEYQHSLERLR
EGQRLVEREQARMRAQQSLLGHWKHGRQRSLPA
VLLPGGPEVMELNRSESLCHENSFFINEALVQMS
FNTFNKLNPSVIHQDATYPTTQSHSDLVRTSEH
QVDLKVDPSQPSNVSHKLWTAAGSGHQILPFHE
SSKDSCKNGN*HFKHHLYSLNKKLSL*MVGSCVE
*IKVLPSMGINRY**AG

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