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Sequences

Sequence NM_012272

GGCTCGGGGCGGTCCCACAGCGCCCCCTGCGGCCCGGGCCGTGGCCGATGGGGCGGGGAGGCCGCTGGGGATAGCTGGGACCCCGGGGAGGGCGAGGGAG
GCCAAGGGTGAGGGAAGAGAGCCCGGGAGGGGGGATGGGGGCGGGGACTGGGGGCGAAGGGGCGGGGGAGGCCATGATGGAGCCTGGCCGGGGGCGAAAG
GTGCGAGAGTGGCGGGACTGGGTGAAGAGTGGGATTGGGAGAGGTGGGGGTGGGTTCGCGGAGAAAGATCGGGAAAGAAGAGAGAGGGCGGAGATGAGGG
GACTGAGGGGACCAGGGGACAGGTGGGGACCAGTTTCCCCTCCTGGGATATTTGGTGTGCGACATGCCCTTCCCCCAGCCCCAGCGCCCGTTCCCTTTGG
AAGCCTGGGTGCTCCTCAGACCACTTGGGGACTCCCTGCTTCACCTTCCTGCATTTGCAAGAGCTTGTCTCCTGAGGTGGAGAGGGGGCCTCTGAAGAAA
GGGGCTCCCAGCCCAGGCCATCAACAAACTAACGACTCTGTGTGACCTTGGATGCCCCCTCCAGGGATCCCCCCACCCTTTCCTCCGATGGGGCTACCCC
CCATGAGTCAGAGACCACCAGCTATCCCCCCCATGCCACCTGGCATCCTGCCCCCAATGCTTCCACCAATGGGGGCGCCACCACCACTCACACAGATACC
AGGAATGGTACCTCCGATGATGCCAGGAATGCTGATGCCAGCGGTGCCTGTCACCGCAGCGACGGCTCCGGGTGCGGACACCGCCAGCTCTGCTGTGGCT
GGGACAGGCCCTCCGAGGGCCCTATGGAGTGAGCATGTGGCCCCAGATGGGCGCATCTACTACTACAATGCTGACGACAAGCAGTCCGTGTGGGAGAAGC
CCAGCGTGCTCAAGTCCAAGGCAGAGCTGCTCCTGTCCCAATGTCCCTGGAAAGAGTACAAGTCGGACACAGGCAAACCTTATTACTATAACAACCAGAG
TAAAGAGTCCCGCTGGACCCGGCCCAAGGATCTGGATGACCTAGAGGTTCTAGTCAAACAAGAGGCTGCAGGGAAACAGCAGCAGCAGCTGCCACAGACA
CTTCAGCCACAGCCACCTCAGCCACAGCCTGACCCCCCACCTGTGCCTCCTGGCCCCACCCCAGTGCCCACAGGCCTCCTGGAACCTGAGCCAGGTGGGA
GTGAAGATTGTGATGTGTTGGAGGCCACCCAGCCCCTGGAACAGGGGTTCCTGCAGCAGCTGGAGGAGGGCCCCAGCAGTTCTGGACAGCATCAGCCACA
GCAGGAGGAGGAGGAATCAAAGCCAGAACCAGAGAGGTCTGGCCTCAGTTGGAGCAACCGGGAGAAGGCAAAGCAGGCATTCAAGGAACTGCTGAGGGAC
AAGGCTGTCCCCTCCAATGCCTCATGGGAACAGGCCATGAAGATGGTGGTCACCGACCCCCGTTACAGTGCCTTGCCTAAACTGAGTGAGAAAAAGCAGG
CATTCAATGCCTACAAGGCGCAGCGGGAGAAGGAGGAGAAGGAGGAGGCCCGGCTAAGGGCCAAAGAGGCCAAGCAGACCCTGCAGCATTTCCTGGAGCA
GCATGAACGCATGACCTCCACCACCCGCTACCGGCGGGCAGAACAGACCTTTGGGGAGCTGGAGGTCTGGGCTGTGGTCCCTGAGAGGGATCGAAAAGAG
GTTTATGATGATGTCCTCTTCTTCCTGGCCAAGAAGGAGAAGGAACAGGCCAAGCAGCTCCGGCGCCGCAATATCCAGGCCCTAAAGAGCATCCTGGATG
GGATGAGTAGTGTCAACTTCCAAACCACGTGGTCCCAGGCCCAGCAGTACCTCATGGATAACCCCAGCTTTGCTCAGGACCATCAGCTGCAGAACATGGA
CAAGGAAGATGCACTGATCTGTTTTGAGGAGCACATCCGAGCTTTGGAGAGGGAAGAGGAGGAGGAACGGGAGCGGGCCCGGCTTCGGGAGCGACGCCAA
CAACGCAAGAATCGGGAGGCCTTCCAGACCTTCCTGGACGAGCTGCATGAGACAGGGCAGCTGCACTCTATGTCCACCTGGATGGAGCTATATCCAGCAG
TCAGCACTGATGTCCGCTTTGCCAACATGCTGGGCCAGCCGGGCTCCACCCCTCTGGACTTATTCAAGTTCTATGTGGAGGAGTTGAAGGCACGATTCCA
TGATGA
AAAGAAGATCATTAAGGACATCCTTAAGGTGAACACGGCCTTTGAGGACTTCGCCCACGTCATAAGCTTTGACAAGAGGGCTGCCGCACTGGAC
GCAGGCAACATCAAGCTGACCTTCAATAGTCTGCTGGAGAAAGCAGAGGCACGGGAGAGGGAGCGGGAGAAGGAGGAGGCACGCAGGATGCGGCGCAGGG
AAGCTGCCTTTCGAAGCATGCTGAGGCAGGCTGTGCCTGCTCTGGAGCTAGGCACTGCCTGGGAAGAGGTCCGTGAGCGTTTTGTGTGTGACTCAGCCTT
TGAGCAGATCACCCTGGAGTCGGAGCGGATCCGGCTCTTCCGGGAGTTCCTACAGGTGCTGGAGCAGACTGAATGCCAGCACCTCCACACCAAAGGCCGA
AAGCATGGCAGGAAAGGCAAGAAGCACCATCACAAGCGTTCCCACTCACCCTCAGGCTCTGAGTCAGAAGAAGAGGAGCTGCCCCCACCATCTCTCCGGC
CCCCCAAGCGGAGGAGGCGGAACCCCTCAGAGTCAGGCTCTGAGCCCTCTTCCTCACTTGATTCAGTTGAAAGTGGGGGTGCTGCCCTTGGAGGACGGGG
CTCCCCTTCCTCCCATCTTCTTGGAGCAGATCATGGCCTTCGGAAAGCCAAGAAACCAAAAAAGAAAACTAAGAAGAGAAGACACAAGTCGAATAGTCCT
GAGAGTGAGACAGACCCTGAGGAGAAAGCTGGCAAGGAGAGCGATGAGAAAGAACAAGAACAGGACAAGGACAGGGAGCTCCAACAGGCAGAGCTCCCTA
ACCGTTCCCCAGGCTTTGGAATCAAGAAGGAGAAGACAGGCTGGGACACGTCAGAAAGTGAGCTGAGTGAGGGTGAGCTGGAGAGGCGGCGGCGGACACT
CCTACAGCAGCTGGATGATCACCAGTGACCCAATGAGCTGTTCTCTGCCTCGGGTCTGTGTGAGGCCATGGCTCCTGGGCCACCCTCACCGTCTGCCTCA
GACTTCTTCCTTAGTCTGGTCTGTGTCCACTTTTTCTAAAGTAACCCCACCCCCAGCACACCATTGTTGGCACCTCTCAAGGTTGCTCTTGGTGTTCAAG
GGTCCCCTACTCCCTGGACTAGTGCAGTCCTTGCCCTCAGCCCCAGACCAGAGATGGGTGGTATATGCCATGTGGGGTGGGTGATGCCAGTAGATAAAAG
TGTGAGAGAAGGGGTCTCCAGGGAAGAGTCACAGGCTGTTGGACGCAGCCTGGGTGGCAGAGGGCAGGGTCATCACCCTCTAGCATCAGTGCCTGCTCCT
GCCTGCCCTGGCCCTGAGGCTCCACCACTTCTTCCTCCACCCAGGACCTAATGTACGTGTGTTTTGTTTTTTGTTTTTTAAATAACAATATTTATAACAT
GG
  • refseq_PRPF40B.F2 (forward primer)
  • refseq_PRPF40B.R2 (reverse primer)
  • Alternative acceptor

Frame 0

GSGRSHSAPCGPGRGRWGGEAAGDSWDPGEGEG
GQG*GKRAREGGWGRGLGAKGRGRP*WSLAGGER
CESGGTG*RVGLGEVGVGSRRKIGKEERGRR*G
D*GDQGTGGDQFPLLGYLVCDMPFPQPQRPFPL
EAWVLLRPLGDSLLHLPAFARACLLRWRGGL*RK
GLPAQAINKLTTLCDLGCPLQGSPHPFLRWGYP
P*VRDHQLSPPCHLASCPQCFHQWGRHHHSHRY
QEWYLR*CQEC*CQRCLSPQRRLRVRTPPALLWL
GQALRGPYGVSMWPQMGASTTTMLTTSSPCGRS
PACSSPRQSCSCPNVPGKSTSRTQANLITITTR
VKSPAGPGPRIWMT*RF*SNKRLQGNSSSSCHRH
FSHSHLSHSLTPHLCLLAPPQCPQASWNLSQVG
VKIVMCWRPPSPWNRGSCSSWRRAPAVLDSISH
SRRRRNQSQNQRGLASVGATGRRQSRHSRNC*GT
RLSPPMPHGNRP*RWWSPTPVTVPCLN*VRKSR
HSMPTRRSGRRRRRRRPG*GPKRPSRPCSISWS
SMNA*PPPPATGGQNRPLGSWRSGLWSLRGIEKR
FMMMSSSSWPRRRRNRPSSSGAAISRP*RASWM
G*VVSTSKPRGPRPSSTSWITPALLRTISCRTW
TRKMH*SVLRSTSELWRGKRRRNGSGPGFGSDAN
NARIGRPSRPSWTSCMRQGSCTLCPPGWSYIQQ
SALMSALPTCWASRAPPLWTYSSSMWRS*RHDS
MM
KRRSLRTSLR*TRPLRTSPTS*ALTRGLPHWT
QATSS*PSIVCWRKQRHGRGSGRRRRHAGCGAG
KLPFEAC*GRLCLLWS*ALPGKRSVSVLCVTQP
LSRSPWSRSGSGSSGSSYRCWSRLNASTSTPKAE
SMAGKARSTITSVPTHPQALSQKKRSCPHHLSG
PPSGGGGTPQSQALSPLPHLIQLKVGVLPLEDG
APLPPIFLEQIMAFGKPRNQKRKLRREDTSRIVL
RVRQTLRRKLARRAMRKNKNRTRTGSSNRQSSL
TVPQALESRRRRQAGTRQKVS*VRVSWRGGGGH
SYSSWMITSDPMSCSLPRVCVRPWLLGHPHRLPQ
TSSLVWSVSTFSKVTPPPAHHCWHLSRLLLVFK
GPLLPGLVQSLPSAPDQRWVVYAMWGG*CQ*IK
V*EKGSPGKSHRLLDAAWVAEGRVITL*HQCLLL
PALALRLHHFFLHPGPNVRVFCFLFFK*QYL*H

Frame 1

ARGGPTAPPAARAVADGAGRPLGIAGTPGRARE
AKGEGREPGRGDGGGDWGRRGGGGHDGAWPGAK
GARVAGLGEEWDWERWGWVRGERSGKKREGGDEG
TEGTRGQVGTSFPSWDIWCATCPSPSPSARSLW
KPGCSSDHLGTPCFTFLHLQELVS*GGEGASEE
RGSQPRPSTN*RLCVTLDAPSRDPPTLSSDGATP
HESETTSYPPHATWHPAPNASTNGGATTTHTDT
RNGTSDDARNADASGACHRSDGSGCGHRQLCCG
WDRPSEGPME*ACGPRWAHLLLQC*RQAVRVGEA
QRAQVQGRAAPVPMSLERVQVGHRQTLLL*QPE
*RVPLDPAQGSG*PRGSSQTRGCRETAAAAATD
TSATATSATA*PPTCASWPHPSAHRPPGT*ARWE
*RL*CVGGHPAPGTGVPAAAGGGPQQFWTASAT
AGGGGIKARTREVWPQLEQPGEGKAGIQGTAEG
QGCPLQCLMGTGHEDGGHRPPLQCLA*TE*EKAG
IQCLQGAAGEGGEGGGPAKGQRGQADPAAFPGA
A*THDLHHPLPAGRTDLWGAGGLGCGP*EGSKR
GL**CPLLPGQEGEGTGQAAPAPQYPGPKEHPGW
DE*CQLPNHVVPGPAVPHG*PQLCSGPSAAEHG
QGRCTDLF*GAHPSFGEGRGGGTGAGPASGATP
TTQESGGLPDLPGRAA*DRAAALYVHLDGAISSS
QH*CPLCQHAGPAGLHPSGLIQVLCGGVEGTIP
**
KEDH*GHP*GEHGL*GLRPRHKL*QEGCRTG
RRQHQADLQ*SAGESRGTGEGAGEGGGTQDAAQG
SCLSKHAEAGCACSGARHCLGRGP*AFCV*LSL
*ADHPGVGADPALPGVPTGAGAD*MPAPPHQRP
KAWQERQEAPSQAFPLTLRL*VRRRGAAPTISPA
PQAEEAEPLRVRL*ALFLT*FS*KWGCCPWRTG
LPFLPSSWSRSWPSESQETKKEN*EEKTQVE*S
*E*DRP*GESWQGER*ERTRTGQGQGAPTGRAP*
PFPRLWNQEGEDRLGHVRK*AE*G*AGEAAADT
PTAAG*SPVTQ*AVLCLGSV*GHGSWATLTVCL
RLLP*SGLCPLFLK*PHPQHTIVGTSQGCSWCSR
VPYSLD*CSPCPQPQTRDGWYMPCGVGDASR*K
CERRGLQGRVTGCWTQPGWQRAGSSPSSISACS
CLPWP*GSTTSSSTQDLMYVCFVFCFLNNNIYNM

Frame 2

LGAVPQRPLRPGPWPMGRGGRWG*LGPRGGRGR
PRVREESPGGGMGAGTGGEGAGEAMMEPGRGRK
VREWRDWVKSGIGRGGGGFAEKDRERRERAEMR
GLRGPGDRWGPVSPPGIFGVRHALPPAPAPVPFG
SLGAPQTTWGLPASPSCICKSLSPEVERGPLKK
GAPSPGHQQTNDSV*PWMPPPGIPPPFPPMGLP
PMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP
GMVPPMMPGMLMPAVPVTAATAPGADTASSAVA
GTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK
PSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQS
KESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT
LQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGG
SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ
QEEEESKPEPERSGLSWSNREKAKQAFKELLRD
KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQ
AFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQ
HERMTSTTRYRRAEQTFGELEVWAVVPERDRKE
VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILD
GMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMD
KEDALICFEEHIRALEREEEEERERARLRERRQ
QRKNREAFQTFLDELHETGQLHSMSTWMELYPA
VSTDVRFANMLGQPGSTPLDLFKFYVEELKARFH
DE
KKIIKDILKVNTAFEDFAHVISFDKRAAALD
AGNIKLTFNSLLEKAEAREREREKEEARRMRRR
EAAFRSMLRQAVPALELGTAWEEVRERFVCDSAF
EQITLESERIRLFREFLQVLEQTECQHLHTKGR
KHGRKGKKHHHKRSHSPSGSESEEEELPPPSLR
PPKRRRRNPSESGSEPSSSLDSVESGGAALGGRG
SPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSP
ESETDPEEKAGKESDEKEQEQDKDRELQQAELP
NRSPGFGIKKEKTGWDTSESELSEGELERRRRTL
LQQLDDHQ*PNELFSASGLCEAMAPGPPSPSAS
DFFLSLVCVHFF*SNPTPSTPLLAPLKVALGVQ
GSPTPWTSAVLALSPRPEMGGICHVGWVMPVDKS
VREGVSREESQAVGRSLGGRGQGHHPLASVPAP
ACPGPEAPPLLPPPRT*CTCVLFFVF*ITIFIT
W

Sequence NM_001031698

GTCGGTTCCCGATTCTGGTCCCCGGCCCCCAGCAGCGCCTGCCCCCTTCCCACCGGGGCCCCCCATGATGCCACCACCCTTCATGCCCCCTCCAGGGATC
CCCCCACCCTTTCCTCCGATGGGGCTACCCCCCATGAGTCAGAGACCACCAGCTATCCCCCCCATGCCACCTGGCATCCTGCCCCCAATGCTTCCACCAA
TGGGGGCGCCACCACCACTCACACAGATACCAGGAATGGTACCTCCGATGATGCCAGGAATGCTGATGCCAGCGGTGCCTGTCACCGCAGCGACGGCTCC
GGGTGCGGACACCGCCAGCTCTGCTGTGGCTGGGACAGGCCCTCCGAGGGCCCTATGGAGTGAGCATGTGGCCCCAGATGGGCGCATCTACTACTACAAT
GCTGACGACAAGCAGTCCGTGTGGGAGAAGCCCAGCGTGCTCAAGTCCAAGGCAGAGCTGCTCCTGTCCCAATGTCCCTGGAAAGAGTACAAGTCGGACA
CAGGCAAACCTTATTACTATAACAACCAGAGTAAAGAGTCCCGCTGGACCCGGCCCAAGGATCTGGATGACCTAGAGGTTCTAGTCAAACAAGAGGCTGC
AGGGAAACAGCAGCAGCAGCTGCCACAGACACTTCAGCCACAGCCACCTCAGCCACAGCCTGACCCCCCACCTGTGCCTCCTGGCCCCACCCCAGTGCCC
ACAGGCCTCCTGGAACCTGAGCCAGGTGGGAGTGAAGATTGTGATGTGTTGGAGGCCACCCAGCCCCTGGAACAGGGGTTCCTGCAGCAGCTGGAGGAGG
GCCCCAGCAGTTCTGGACAGCATCAGCCACAGCAGGAGGAGGAGGAATCAAAGCCAGAACCAGAGAGGTCTGGCCTCAGTTGGAGCAACCGGGAGAAGGC
AAAGCAGGCATTCAAGGAACTGCTGAGGGACAAGGCTGTCCCCTCCAATGCCTCATGGGAACAGGCCATGAAGATGGTGGTCACCGACCCCCGTTACAGT
GCCTTGCCTAAACTGAGTGAGAAAAAGCAGGCATTCAATGCCTACAAGGCGCAGCGGGAGAAGGAGGAGAAGGAGGAGGCCCGGCTAAGGGCCAAAGAGG
CCAAGCAGACCCTGCAGCATTTCCTGGAGCAGCATGAACGCATGACCTCCACCACCCGCTACCGGCGGGCAGAACAGACCTTTGGGGAGCTGGAGGTCTG
GGCTGTGGTCCCTGAGAGGGATCGAAAAGAGGTTTATGATGATGTCCTCTTCTTCCTGGCCAAGAAGGAGAAGGAACAGGCCAAGCAGCTCCGGCGCCGC
AATATCCAGGCCCTAAAGAGCATCCTGGATGGGATGAGTAGTGTCAACTTCCAAACCACGTGGTCCCAGGCCCAGCAGTACCTCATGGATAACCCCAGCT
TTGCTCAGGACCATCAGCTGCAGAACATGGACAAGGAAGATGCACTGATCTGTTTTGAGGAGCACATCCGAGCTTTGGAGAGGGAAGAGGAGGAGGAACG
GGAGCGGGCCCGGCTTCGGGAGCGACGCCAACAACGCAAGAATCGGGAGGCCTTCCAGACCTTCCTGGACGAGCTGCATGAGACAGGGCAGCTGCACTCT
ATGTCCACCTGGATGGAGCTATATCCAGCAGTCAGCACTGATGTCCGCTTTGCCAACATGCTGGGCCAGCCGGGCTCCACCCCTCTGGACTTATTCAAGT
TCTATGTGGAGGAGTTGAAGGCACGATTCCATGATGAAAAGAAGATCATTAAGGACATCCTTAAGGACCGGGGCTTCTGCGTGGAGGTGAACACGGCCTT
TGAGGACTTCGCCCACGTCATAAGCTTTGACAAGAGGGCTGCCGCACTGGACGCAGGCAACATCAAGCTGACCTTCAATAGTCTGCTGGAGAAAGCAGAG
GCACGGGAGAGGGAGCGGGAGAAGGAGGAGGCACGCAGGATGCGGCGCAGGGAAGCTGCCTTTCGAAGCATGCTGAGGCAGGCTGTGCCTGCTCTGGAGC
TAGGCACTGCCTGGGAAGAGGTCCGTGAGCGTTTTGTGTGTGACTCAGCCTTTGAGCAGATCACCCTGGAGTCGGAGCGGATCCGGCTCTTCCGGGAGTT
CCTACAGGTGCTGGAGCAGACTGAATGCCAGCACCTCCACACCAAAGGCCGAAAGCATGGCAGGAAAGGCAAGAAGCACCATCACAAGCGTTCCCACTCA
CCCTCAGGCTCTGAGTCAGAAGAAGAGGAGCTGCCCCCACCATCTCTCCGGCCCCCCAAGCGGAGGAGGCGGAACCCCTCAGAGTCAGGCTCTGAGCCCT
CTTCCTCACTTGATTCAGTTGAAAGTGGGGGTGCTGCCCTTGGAGGACGGGGCTCCCCTTCCTCCCATCTTCTTGGAGCAGATCATGGCCTTCGGAAAGC
CAAGAAACCAAAAAAGAAAACTAAGAAGAGAAGACACAAGTCGAATAGTCCTGAGAGTGAGACAGACCCTGAGGAGAAAGCTGGCAAGGAGAGCGATGAG
AAAGAACAAGAACAGGACAAGGACAGGGAGCTCCAACAGGCAGAGCTCCCTAACCGTTCCCCAGGCTTTGGAATCAAGAAGGAGAAGACAGGCTGGGACA
CGTCAGAAAGTGAGCTGAGTGAGGGTGAGCTGGAGAGGCGGCGGCGGACACTCCTACAGCAGCTGGATGATCACCAGTGACCCAATGAGCTGTTCTCTGC
CTCGGGTCTGTGTGAGGCCATGGCTCCTGGGCCACCCTCACCGTCTGCCTCAGACTTCTTCCTTAGTCTGGTCTGTGTCCACTTTTTCTAAAGTAACCCC
ACCCCCAGCACACCATTGTTGGCACCTCTCAAGGTTGCTCTTGGTGTTCAAGGGTCCCCTACTCCCTGGACTAGTGCAGTCCTTGCCCTCAGCCCCAGAC
CAGAGATGGGTGGTATATGCCATGTGGGGTGGGTGATGCCAGTAGATAAAAGTGTGAGAGAAGGGGTCTCCAGGGAAGAGTCACAGGCTGTTGGACGCAG
CCTGGGTGGCAGAGGGCAGGGTCATCACCCTCTAGCATCAGTGCCTGCTCCTGCCTGCCCTGGCCCTGAGGCTCCACCACTTCTTCCTCCACCCAGGACC
TAATGTACGTGTGTTTTGTTTTTTGTTTTTTAAATAACAATATTTATAACATGG
  • refseq_PRPF40B.F2 (forward primer)
  • refseq_PRPF40B.R2 (reverse primer)
  • Alternative acceptor

Frame 0

VGSRFWSPAPSSACPLPTGAPHDATTLHAPSRD
PPTLSSDGATPHESETTSYPPHATWHPAPNASTN
GGATTTHTDTRNGTSDDARNADASGACHRSDGS
GCGHRQLCCGWDRPSEGPME*ACGPRWAHLLLQ
C*RQAVRVGEAQRAQVQGRAAPVPMSLERVQVGH
RQTLLL*QPE*RVPLDPAQGSG*PRGSSQTRGC
RETAAAAATDTSATATSATA*PPTCASWPHPSA
HRPPGT*ARWE*RL*CVGGHPAPGTGVPAAAGGG
PQQFWTASATAGGGGIKARTREVWPQLEQPGEG
KAGIQGTAEGQGCPLQCLMGTGHEDGGHRPPLQ
CLA*TE*EKAGIQCLQGAAGEGGEGGGPAKGQRG
QADPAAFPGAA*THDLHHPLPAGRTDLWGAGGL
GCGP*EGSKRGL**CPLLPGQEGEGTGQAAPAP
QYPGPKEHPGWDE*CQLPNHVVPGPAVPHG*PQL
CSGPSAAEHGQGRCTDLF*GAHPSFGEGRGGGT
GAGPASGATPTTQESGGLPDLPGRAA*DRAAAL
YVHLDGAISSSQH*CPLCQHAGPAGLHPSGLIQV
LCGGVEGTIP**KEDH*GHP*GPGLLRGGEHGL
*GLRPRHKL*QEGCRTGRRQHQADLQ*SAGESR
GTGEGAGEGGGTQDAAQGSCLSKHAEAGCACSGA
RHCLGRGP*AFCV*LSL*ADHPGVGADPALPGV
PTGAGAD*MPAPPHQRPKAWQERQEAPSQAFPL
TLRL*VRRRGAAPTISPAPQAEEAEPLRVRL*AL
FLT*FS*KWGCCPWRTGLPFLPSSWSRSWPSES
QETKKEN*EEKTQVE*S*E*DRP*GESWQGER*
ERTRTGQGQGAPTGRAP*PFPRLWNQEGEDRLGH
VRK*AE*G*AGEAAADTPTAAG*SPVTQ*AVLC
LGSV*GHGSWATLTVCLRLLP*SGLCPLFLK*P
HPQHTIVGTSQGCSWCSRVPYSLD*CSPCPQPQT
RDGWYMPCGVGDASR*KCERRGLQGRVTGCWTQ
PGWQRAGSSPSSISACSCLPWP*GSTTSSSTQD
LMYVCFVFCFLNNNIYNM

Frame 1

SVPDSGPRPPAAPAPFPPGPPMMPPPFMPPPGI
PPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPP
MGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAP
GADTASSAVAGTGPPRALWSEHVAPDGRIYYYN
ADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD
TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAA
GKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVP
TGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEE
GPSSSGQHQPQQEEEESKPEPERSGLSWSNREKA
KQAFKELLRDKAVPSNASWEQAMKMVVTDPRYS
ALPKLSEKKQAFNAYKAQREKEEKEEARLRAKE
AKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVW
AVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRR
NIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS
FAQDHQLQNMDKEDALICFEEHIRALEREEEEER
ERARLRERRQQRKNREAFQTFLDELHETGQLHS
MSTWMELYPAVSTDVRFANMLGQPGSTPLDLFK
FYVEELKARFHDEKKIIKDILKDRGFCVEVNTAF
EDFAHVISFDKRAAALDAGNIKLTFNSLLEKAE
AREREREKEEARRMRRREAAFRSMLRQAVPALE
LGTAWEEVRERFVCDSAFEQITLESERIRLFREF
LQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHS
PSGSESEEEELPPPSLRPPKRRRRNPSESGSEP
SSSLDSVESGGAALGGRGSPSSHLLGADHGLRKA
KKPKKKTKKRRHKSNSPESETDPEEKAGKESDE
KEQEQDKDRELQQAELPNRSPGFGIKKEKTGWD
TSESELSEGELERRRRTLLQQLDDHQ*PNELFSA
SGLCEAMAPGPPSPSASDFFLSLVCVHFF*SNP
TPSTPLLAPLKVALGVQGSPTPWTSAVLALSPR
PEMGGICHVGWVMPVDKSVREGVSREESQAVGRS
LGGRGQGHHPLASVPAPACPGPEAPPLLPPPRT
*CTCVLFFVF*ITIFITW

Frame 2

RFPILVPGPQQRLPPSHRGPP*CHHPSCPLQGS
PHPFLRWGYPP*VRDHQLSPPCHLASCPQCFHQ
WGRHHHSHRYQEWYLR*CQEC*CQRCLSPQRRL
RVRTPPALLWLGQALRGPYGVSMWPQMGASTTTM
LTTSSPCGRSPACSSPRQSCSCPNVPGKSTSRT
QANLITITTRVKSPAGPGPRIWMT*RF*SNKRL
QGNSSSSCHRHFSHSHLSHSLTPHLCLLAPPQCP
QASWNLSQVGVKIVMCWRPPSPWNRGSCSSWRR
APAVLDSISHSRRRRNQSQNQRGLASVGATGRR
QSRHSRNC*GTRLSPPMPHGNRP*RWWSPTPVTV
PCLN*VRKSRHSMPTRRSGRRRRRRRPG*GPKR
PSRPCSISWSSMNA*PPPPATGGQNRPLGSWRS
GLWSLRGIEKRFMMMSSSSWPRRRRNRPSSSGAA
ISRP*RASWMG*VVSTSKPRGPRPSSTSWITPA
LLRTISCRTWTRKMH*SVLRSTSELWRGKRRRN
GSGPGFGSDANNARIGRPSRPSWTSCMRQGSCTL
CPPGWSYIQQSALMSALPTCWASRAPPLWTYSS
SMWRS*RHDSMMKRRSLRTSLRTGASAWR*TRP
LRTSPTS*ALTRGLPHWTQATSS*PSIVCWRKQR
HGRGSGRRRRHAGCGAGKLPFEAC*GRLCLLWS
*ALPGKRSVSVLCVTQPLSRSPWSRSGSGSSGS
SYRCWSRLNASTSTPKAESMAGKARSTITSVPTH
PQALSQKKRSCPHHLSGPPSGGGGTPQSQALSP
LPHLIQLKVGVLPLEDGAPLPPIFLEQIMAFGK
PRNQKRKLRREDTSRIVLRVRQTLRRKLARRAMR
KNKNRTRTGSSNRQSSLTVPQALESRRRRQAGT
RQKVS*VRVSWRGGGGHSYSSWMITSDPMSCSL
PRVCVRPWLLGHPHRLPQTSSLVWSVSTFSKVTP
PPAHHCWHLSRLLLVFKGPLLPGLVQSLPSAPD
QRWVVYAMWGG*CQ*IKV*EKGSPGKSHRLLDA
AWVAEGRVITL*HQCLLLPALALRLHHFFLHPGP
NVRVFCFLFFK*QYL*H

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