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Sequences

Sequence NM_003894

refseq_PER2.F1 (forward primer)
refseq_PER2.R1 (reverse primer)
Single exon skipping

Frame 0

VVEPRAGCARLNCGDTEGWGLEPPLRSSGA*GP KASFQSPA*MDTRNFRPAPVTPPRSPWSPSPARS HCRKMWT*AVAPVDMRPTKTAPRGGTRRAVTVT TVGRSWGCWWSHRMPARVQIPLA**WQNLNTTH LQVAAVATSLRKWTHTKN**KH*RS*RSTSLQTR RPRARPVRWPP*STPSGA*SR*KPMKSITSC*C PARVTPVEQTCPPTPWRRWRALPLSTL*RMPIC LRWPCPWCLGRSCTSLTRLHPYFTVKEMPSAMPS LWSSWRLTMWACSTVSPPRTSFPCGACAVEQIL LLKNAWRRNLSFAVSVSGKATRMKSATTPSA*R PTWSRCGTNKVLRVSFAAFCWQRECTLVMKPLEF LLKREFLQPPIHQIVCSRMWMKVLQSGGQPFDY SPIRFRARNGEYITLDTSWSSFINPWSRKISFI IGRHKVRVGPLN

Frame 1

WSSRAQGALV*TAVTPRVGDSNPRFAAQEPEVR KLRSRAQHEWIRGISAQPQ*PHQGARGAPAQPG PTAGRCGHEQWLQWT*DQRKLLHGAGLAGQ*L*R QWEGAGDAGGATGCPPESRYL*PDDGKI*TQPI YKWLQ*RPVFESGHTQRTDKNTKGAEGPPPCRQ EGQGQGQYAGHLEVRPQEREAGESQ*RVLPAADV QRGSPLWSRRALLHRGGDGERYL*AHCEECRYV CGGRVPGVWEDPVHL*PGCIHISL*KRCLQRCQ VCGVPGASRCGRVPQFHLPVQASLVEHVQWSRFF YSRMHGGEIFLLPCQCPEKPRE*NPLPPLPHDA LPGQGAGPTRC*ESALLPSAGRESALWL*SP*N SS*KENFYNHPYTKLFVPGCG*KSCSQAGSLSTI LPFGFAPGTESTSRWTPAGPASSTHGAGKSPSS LGGTKSGWAL*M

Frame 2

GRAARRVRSFELR*HRGLGTRTPASQLRSLRSE SFVPEPSMNGYAEFPPSPSNPTKEPVEPQPSQV PLQEDVDMSSGSSGHETNENCSTGRDSQGSDCD DSGKELGMLVEPPDARQSPDTFSLMMAKSEHNPS TSGCSSDQSSKVDTHKELIKTLKELKVHLPADK KAKGKASTLATLKYALRSVKQVKANEEYYQLLM SSEGHPCGADVPSYTVEEMESVTSEHIVKNADMF AVAVSLVSGKILYISDQVASIFHCKRDAFSDAK FVEFLAPHDVGVFHSFTSPYKLPLWSMCSGADS FTQECMEEKSFFCRVSVRKSHENEIRYHPFRMTP YLVKVRDQQGAESQLCCLLLAERVHSGYEAPRI PPEKRIFTTTHTPNCLFQDVDESPAVRRAAFRL FSHSVSRPERRVHHVGHQLVQLHQPMEQENLLHH WEAQSQGGPFE*

Sequence NM_022817

GTGGTCGAGCCGCGCGCAGGGTGCGCTCGTTTGAACTGCGGTGACACCGAGGGTTGGGGACTCGAACCCCCGCTTCGCAGCTCAGGAGCCTGAGGTCCGA AAGCTTCGTTCCAGAGCCCAGCATGAATGGATACGCGGAATTTCCGCCCAGCCCCAGTAACCCCACCAAGGAGCCCGTGGAGCCCCAGCCCAGCCAGGTC CCACTGCAGGAAGATGTGGACATGAGCAGTGGCTCCAGTGGACATGAGACCAACGAAAACTGCTCCACGGGGCGGGACTCGCAGGGCAGTGACTGTGACG ACAGTGGGAAGGAGCTGGGGATGCTGGTGGAGCCACCGGATGCCCGCCAGAGTCCAGATACCTTTAGCCTGATGATGGCAAAATCTGAACACAACCCATC TACAAGTGGCTGCAGTAGCGACCAGTCTTCGAAAGTGGACACACACAAAGAACTGATAAAAACACTAAAGGAGCTGAAGGTCCACCTCCCTGCAGACAAG AAGGCCAAGGGCAAGGCCAGTACGCTGGCCACCTTGAAGTACGCCCTCAGGAGCGTGAAGCAGGTGAAAGCCAATGAAGAGTATTACCAGCTGCTGATGT CCAGCGAGGGTCACCCCTGTGGAGCAGACGTGCCCTCCTACACCGTGGAGGAGATGGAGAGCGTTACCTCTGAGCACATTGTGAAGAATGCCGATATGTT TGCGGTGGCCGTGTCCCTGGTGTCTGGGAAGATCCTGTACATCTCTGACCAGGTTGCATCCATATTTCACTGTAAAAGAGATGCCTTCAGCGATGCCAAG TTTGTGGAGTTCCTGGCGCCTCACGATGTGGGCGTGTTCCACAGTTTCACCTCCCCGTACAAGCTTCCCTTGTGGAGCATGTGCAGTGGAGCAGATTCTT TTACTCAAGAATGCATGGAGGAGAAATCTTTCTTTTGCCGTGTCAGTGTCCGGAAAAGCCACGAGAATGAAATCCGCTACCACCCCTTCCGCATGACGCC CTACCTGGTCAAGGTGCGGGACCAACAAGGTGCTGAGAGTCAGCTTTGCTGCCTTCTGCTGGCAGAGAGAGTGCACTCTGGTTATGAAGCCCCTAGAATT CCTCCTGAAAAGAGAATTTTTACAACCACCCATACACCAAATTGTTTGTTCCAGGATGTGGATGAAAGGGCGGTCCCTCTCCTGGGCTACCTACCTCAGG ACCTGATTGAAACCCCAGTGCTCGTGCAGCTCCACCCTAGTGACAGGCCCTTGATGCTGGCCATCCACAAAAAGATCCTGCAGTCAGGCGGGCAGCCTTT CGACTATTCTCCCATTCGGTTTCGCGCCCGGAACGGAGAGTACATCACGTTGGACACCAGCTGGTCCAGCTTCATCAACCCATGGAGCAGGAAAATCTCC TTCATCATTGGGAGGCACAAAGTCAGGGTGGGCCCTTTGAATGAGGACGTGTTTGCAGCCCACCCCTGCACAGAGGAGAAGGCCCTGCACCCCAGCATTC AGGAGCTCACAGAGCAGATCCACCGGCTCCTGCTGCAGCCCGTCCCCCACAGCGGCTCCAGTGGCTACGGGAGTCTGGGCAGCAACGGGTCCCACGAGCA CCTTATGAGCCAGACCTCCTCCAGCGACAGCAACGGCCATGAGGACTCACGCCGGAGGAGAGCCGAAATTTGTAAAAATGGTAACAAGACCAAAAATAGA AGTCATTATTCTCATGAATCTGGAGAACAAAAGAAAAAATCCGTTACAGAAATGCAAACTAATCCCCCAGCTGAGAAGAAAGCTGTCCCTGCCATGGAAA AGGACAGCCTGGGGGTCAGCTTCCCCGAGGAGTTGGCCTGCAAGAACCAGCCCACCTGCTCCTACCAGCAGATCAGCTGCTTGGACAGCGTCATCAGGTA CTTGGAGAGCTGCAATGAGGCTGCCACCCTGAAGAGGAAATGCGAGTTCCCAGCAAACGTCCCAGCGCTAAGGTCCAGTGATAAGCGGAAGGCCACAGTC AGCCCAGGGCCACACGCTGGAGAGGCAGAGCCGCCCTCCAGGGTGAACAGCCGCACGGGAGTAGGTACGCACCTGACCTCGCTGGCACTGCCGGGCAAGG CAGAGAGTGTGGCGTCGCTCACCAGCCAGTGCAGCTACAGCAGCACCATCGTCCATGTGGGAGACAAGAAGCCGCAGCCGGAGTTAGAGATGGTGGAAGA TGCTGCGAGTGGGCCAGAATCCCTGGACTGCCTGGCGGGCCCTGCCCTGGCCTGTGGTCTCAGCCAAGAGAAGGAGCCCTTCAAGAAGCTGGGCCTCACC AAGGAGGTACTCGCTGCACACACACAGAAGGAGGAGCAGAGCTTCCTGCAGAAGTTCAAAGAAATAAGAAAACTCAGCATTTTCCAGTCCCACTGCCATT ACTACTTGCAAGAAAGATCCAAGGGGCAGCCAAGTGAACGAACTGCCCCTGGACTAAGAAATACTTCCGGAATAGATTCACCTTGGAAAAAAACAGGAAA GAACAGAAAATTGAAGTCCAAGCGGGTCAAACCTCGAGACTCATCTGAGAGCACCGGATCTGGGGGGCCCGTGTCCGCCCGGCCCCCGCTGGTGGGCTTG AACGCCACAGCCTGGTCACCCTCAGACACGTCCCAGTCCAGCTGCCCAGCCGTGCCCTTTCCCGCCCCAGTGCCAGCAGCTTATTCACTGCCCGTGTTTC CAGCGCCAGGGACTGTGGCAGCACCCCCGGCACCTCCCCACGCCAGCTTCACAGTGCCTGCTGTGCCCGTGGACCTCCAGCACCAGTTTGCAGTCCAGCC CCCACCTTTCCCTGCCCCTTTGGCGCCTGTCATGGCATTCATGCTACCCAGTTATTCCTTCCCCTCGGGGACCCCAAACCTGCCCCAGGCCTTCTTCCCC AGCCAGCCTCAGTTTCCGAGCCACCCCACACTCACATCCGAGATGGCCTCTGCCTCACAGCCTGAGTTCCCCAGCCGGACCTCGATCCCCAGACAGCCAT GTGCTTGTCCAGCCACCCGGGCCACCCCACCATCGGCCATGGGTAGGGCCTCCCCACCGCTCTTTCAGTCCCGCAGCAGCTCGCCCCTGCAGCTCAACCT GCTGCAGCTGGAGGAAGCCCCTGAGGGTGGCACTGGAGCCATGGGGACCACAGGGGCCACAGAGACAGCAGCTGTAGGGGCGGACTGCAAACCTGGCACT TCTCGGGACCAGCAGCCGAAGGCGCCTCTGACCCGTGATGAACCCTCAGACACACAGAACAGTGACGCCCTTTCCACGTCAAGCGGCCTCCTAAACCTCC TGCTGAATGAGGACCTCTGCTCAGCCTCGGGCTCTGCTGCTTCGGAGTCTCTGGGCTCCGGCTCACTGGGCTGCGACGCCTCCCCGAGTGGGGCAGGCAG TAGTGACACAAGTCATACCAGCAAATATTTTGGAAGCATTGACTCCTCAGAGAATAATCACAAAGCAAAAATGAACACTGGTATGGAAGAAAGTGAGCAT TTCATTAAGTGCGTCCTGCAGGATCCCATCTGGCTGCTGATGGCAGATGCGGACAGCAGCGTCATGATGACGTACCAGCTGCCTTCCCGAAATTTAGAAG CGGTTTTGAAGGAGGACAGAGAGAAGCTGAAGCTCCTACAGAAACTCCAGCCCAGGTTCACGGAGAGTCAGAAGCAGGAGCTGCGCGAGGTCCACCAGTG GATGCAGACGGGCGGCCTGCCCGCAGCCATCGACGTGGCAGAATGTGTTTACTGTGAAAACAAGGAAAAAGGTAATATTTGCATACCATATGAGGAAGAT ATTCCTTCTCTGGGACTCAGCGAAGTGTCGGACACCAAAGAAGACGAAAATGGATCCCCCTTGAATCACAGGATCGAAGAGCAGACGTAACCCCTGCCCC ACCTCAGCCCGGCAGCCAGCGAGGTACACCAGGTGGTGCTTGGAAGAGATGAAAGATCTTCATGGCTGTTTCCACTGAAATGGACACATATGCTCATGTT GCTTTTTTTGTTTTAGAAAAAAAAACAACATAGTTTTCTGAAGGGGCGACTTAAAACTGTGGAGAGTGGGGAGAGTTCGGAAAGAAATATGTTTTTATAT ATAAAATATATATGTGGAGTTTTGTGGGATGGGGAAGAGATTTTAGTTGTTATTTAACTTGAGAAAGACTAAGCGCCTCTTAGTGTCAGGGAAGTTGCCT CAGTGCTCCCAGAAGTCCTGTGACTGTGACGAGACCTCTGTCTGCTGCACCAGCTGGGGACTCTGGCTTCCAGAGCTTTCCCAGGGTGTTTGGATCAGAT CAAATTTTGTCCTCTCTTGGGGACTGCTTTTTATCTGAATTATCATTTAGTCAAGGTAGAGTGTTTTTTTATACATACCAAATGGAGATAGCAGCCTCTC CTAGTTTTATTTCAAAACGTTTCACATTAAATGGTGTGAAGCGTTGTTTGGCAAACCAACAGCTTTGGCTTCTGGTGTGGTCAATATTTCAGTCTGACAT AGGTTTTGTTTGTAGTGAACAAAGTTGAAACATTTGCTCTGGACTAAAGAAGCCTAGTGGTTTGTGTGGCCAACTCCATCGGATGAATGCACACGCAGAC AGACCCTCTGTATATTTCTGCATTATTCTTGTCTCCTTTTCAGACCATGATGGCCAATATGGAGATTAAAATATGTCATCAGTCATCTCTTTATGGTGAC TTCCCTTTGCAAACCAGGCTGTGACCAACACATGTGAGACCCAGTCCTGTTTGGTTTTCTTCCGTTGGAACCACCCAGACATCTGCTTCCACCCAGCCAA GCCCACATCACATCTCCTGGCCGAGAGCAGCCACTGCCACTCAGTCTGACAGCTTGCGACTGCATCTGTATTTTCAGGGGTGCAGTGAGCTCACCTCTCC CACTGCACCCTGGGTTGGGTGCACAGCCCTCATTCTTTTCATGAGCCCGACCTCTCTCGGAGCAGCTTCAGGCCTCTGCCAGTGTCCCCAGCACTTTTAG GTCATTTGGACACTTGGGGAAAAGTGAGGCCAGTCTGCCCGGCTTTTTACAAAACCTCATGTTGCATTGTATATTCCAAAGATGGTTCAGAAAATTTAAT ATTGGTCCCTGGTGGAAATTCAAAGTTATCACTGAAGAACAGTTGACTTAAAATTGGACCAAGACTATGAGGCTTAAAAGGGACCAGGGTTTTCTTTTTT TTTTTTTTTTTTTTTTTTTTTTAGATGGAGTTTCTTTTTGCCCAGGCTGGAGTGCAGTGGCGCCATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCA AGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACCACAGGCGACTGCCACCACACCCAGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCAC CATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGCGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCCAAC TGGGACCAGGGTTTTCTGTTTTTTGATGGAGGTGAAATCTCTTTGTAATCCACTAGGTTTTCATCGTAAAACCATCTTATGCCTGACTATTAAACCTATT CTTCATAAACACAAGAACACTTTAATTTTTCGTTAATTTACAAAGTAACATCAGCTGCCTATGCCTATGATAAGGTAGCAGTCTGCATTCTTATGGCCAT TAGATGTTACAAACTCCTTGCCTCTAAAGTCAGATCATGAAGGGATAGGTGTTCATCTAAGGTTACAGTTATGTTACCGAAACACAAAACTGCCAAAATC TTACTCTGCTGTTATGAATGTTTACCATCAGCATTATTTTATCATTTAATATGTGCTCACTGATTGTTAACTGTAGCTTCAGCGCGTGCCAAGCAGTTGA CTTAATAGGATCATCTTGTGAATTTGTTTACGTGATGCCAAGCATCAAGTCATGTTTTCTTTAGTGTGTGTGCTTACACAGGTGTTAAACAGTTTTTCTC TATTTTAAACTGAGCCTTCTTTTTAATATATTCCCGAAGAGATATGTAAATAAGCTCTCAGAGTTTCTGTGATGATTTGTTGAGCCTTGCTGGACAAGTG GTTTGTTTGTGTGCAAACCAAACTTTCTTTACCCAGTGCAATAGATTTGTTTGACTGCTTGTGTCTTTTTATGACCTGTTTGCCTTTTAGAAAATTGGTA AATAAAGCAAGTATATTTTT

refseq_PER2.F1 (forward primer)
refseq_PER2.R1 (reverse primer)
Single exon skipping

Frame 0

VVEPRAGCARLNCGDTEGWGLEPPLRSSGA*GP KASFQSPA*MDTRNFRPAPVTPPRSPWSPSPARS HCRKMWT*AVAPVDMRPTKTAPRGGTRRAVTVT TVGRSWGCWWSHRMPARVQIPLA**WQNLNTTH LQVAAVATSLRKWTHTKN**KH*RS*RSTSLQTR RPRARPVRWPP*STPSGA*SR*KPMKSITSC*C PARVTPVEQTCPPTPWRRWRALPLSTL*RMPIC LRWPCPWCLGRSCTSLTRLHPYFTVKEMPSAMPS LWSSWRLTMWACSTVSPPRTSFPCGACAVEQIL LLKNAWRRNLSFAVSVSGKATRMKSATTPSA*R PTWSRCGTNKVLRVSFAAFCWQRECTLVMKPLEF LLKREFLQPPIHQIVCSRMWMKGRSLSWATYLR T*LKPQCSCSSTLVTGP*CWPSTKRSCSQAGSL STILPFGFAPGTESTSRWTPAGPASSTHGAGKSP SSLGGTKSGWAL*MRTCLQPTPAQRRRPCTPAF RSSQSRSTGSCCSPSPTAAPVATGVWAATGPTS TL*ARPPPATATAMRTHAGGEPKFVKMVTRPKIE VIILMNLENKRKNPLQKCKLIPQLRRKLSLPWK RTAWGSASPRSWPARTSPPAPTSRSAAWTASSG TWRAAMRLPP*RGNASSQQTSQR*GPVISGRPQS AQGHTLERQSRPPG*TAARE*VRT*PRWHCRAR QRVWRRSPASAATAAPSSMWETRSRSRS*RWWK MLRVGQNPWTAWRALPWPVVSAKRRSPSRSWASP RRYSLHTHRRRSRASCRSSKK*ENSAFSSPTAI TTCKKDPRGSQVNELPLD*EILPE*IHLGKKQE RTEN*SPSGSNLETHLRAPDLGGPCPPGPRWWA* TPQPGHPQTRPSPAAQPCPFPPQCQQLIHCPCF QRQGLWQHPRHLPTPASQCLLCPWTSSTSLQSS PHLSLPLWRLSWHSCYPVIPSPRGPQTCPRPSSP ASLSFRATPHSHPRWPLPHSLSSPAGPRSPDSH VLVQPPGPPHHRPWVGPPHRSFSPAAARPCSST CCSWRKPLRVALEPWGPQGPQRQQL*GRTANLAL LGTSSRRRL*PVMNPQTHRTVTPFPRQAAS*TS C*MRTSAQPRALLLRSLWAPAHWAATPPRVGQA VVTQVIPANILEALTPQRIITKQK*TLVWKKVSI SLSASCRIPSGC*WQMRTAAS**RTSCLPEI*K RF*RRTERS*SSYRNSSPGSRRVRSRSCARSTS GCRRAACPQPSTWQNVFTVKTRKKVIFAYHMRKI FLLWDSAKCRTPKKTKMDPP*ITGSKSRRNPCP TSARQPARYTRWCLEEMKDLHGCFH*NGHICSC CFFCFRKKNNIVF*RGDLKLWRVGRVRKEICFYI *NIYVEFCGMGKRF*LLFNLRKTKRLLVSGKLP QCSQKSCDCDETSVCCTSWGLWLPELSQGVWIR SNFVLSWGLLFI*III*SR*SVFLYIPNGDSSLS *FYFKTFHIKWCEALFGKPTALASGVVNISV*H RFCL**TKLKHLLWTKEA*WFVWPTPSDECTRR QTLCIFLHYSCLLFRP*WPIWRLKYVISHLFMVT SLCKPGCDQHM*DPVLFGFLPLEPPRHLLPPSQ AHITSPGREQPLPLSLTACDCICIFRGAVSSPL PLHPGLGAQPSFFS*ARPLSEQLQASASVPSTFR SFGHLGKSEASLPGFLQNLMLHCIFQRWFRKFN IGPWWKFKVITEEQLT*NWTKTMRLKRDQGFLF FFFFFFFLDGVSFCPGWSAVAPSWLTATSASQVQ AILLPQPPE*LGPQATATTPS*FFVFLVETGFH HVGQAGLELLTSSDPPTSASQSAGITGVSHHAQ LGPGFSVF*WR*NLFVIH*VFIVKPSYA*LLNLF FINTRTL*FFVNLQSNISCLCL**GSSLHSYGH *MLQTPCL*SQIMKG*VFI*GYSYVTETQNCQN LTLLL*MFTISIILSFNMCSLIVNCSFSACQAVD LIGSSCEFVYVMPSIKSCFL*CVCLHRC*TVFL YFKLSLLFNIFPKRYVNKLSEFL**FVEPCWTS GLFVCKPNFLYPVQ*ICLTACVFL*PVCLLENW* IKQVYF

Frame 1

WSSRAQGALV*TAVTPRVGDSNPRFAAQEPEVR KLRSRAQHEWIRGISAQPQ*PHQGARGAPAQPG PTAGRCGHEQWLQWT*DQRKLLHGAGLAGQ*L*R QWEGAGDAGGATGCPPESRYL*PDDGKI*TQPI YKWLQ*RPVFESGHTQRTDKNTKGAEGPPPCRQ EGQGQGQYAGHLEVRPQEREAGESQ*RVLPAADV QRGSPLWSRRALLHRGGDGERYL*AHCEECRYV CGGRVPGVWEDPVHL*PGCIHISL*KRCLQRCQ VCGVPGASRCGRVPQFHLPVQASLVEHVQWSRFF YSRMHGGEIFLLPCQCPEKPRE*NPLPPLPHDA LPGQGAGPTRC*ESALLPSAGRESALWL*SP*N SS*KENFYNHPYTKLFVPGCG*KGGPSPGLPTSG PD*NPSARAAPP**QALDAGHPQKDPAVRRAAF RLFSHSVSRPERRVHHVGHQLVQLHQPMEQENL LHHWEAQSQGGPFE*GRVCSPPLHRGEGPAPQHS GAHRADPPAPAAARPPQRLQWLRESGQQRVPRA PYEPDLLQRQQRP*GLTPEESRNL*KW*QDQK* KSLFS*IWRTKEKIRYRNAN*SPS*EESCPCHGK GQPGGQLPRGVGLQEPAHLLLPADQLLGQRHQV LGELQ*GCHPEEEMRVPSKRPSAKVQ**AEGHS QPRATRWRGRAALQGEQPHGSRYAPDLAGTAGQG RECGVAHQPVQLQQHHRPCGRQEAAAGVRDGGR CCEWARIPGLPGGPCPGLWSQPREGALQEAGPH QGGTRCTHTEGGAELPAEVQRNKKTQHFPVPLPL LLARKIQGAAK*TNCPWTKKYFRNRFTLEKNRK EQKIEVQAGQTSRLI*EHRIWGARVRPAPAGGL ERHSLVTLRHVPVQLPSRALSRPSASSLFTARVS SARDCGSTPGTSPRQLHSACCARGPPAPVCSPA PTFPCPFGACHGIHATQLFLPLGDPKPAPGLLP QPASVSEPPHTHIRDGLCLTA*VPQPDLDPQTAM CLSSHPGHPTIGHG*GLPTALSVPQQLAPAAQP AAAGGSP*GWHWSHGDHRGHRDSSCRGGLQTWH FSGPAAEGASDP**TLRHTEQ*RPFHVKRPPKPP AE*GPLLSLGLCCFGVSGLRLTGLRRLPEWGRQ **HKSYQQIFWKH*LLRE*SQSKNEHWYGRK*A FH*VRPAGSHLAADGRCGQQRHDDVPAAFPKFRS GFEGGQREAEAPTETPAQVHGESEAGAARGPPV DADGRPARSHRRGRMCLL*KQGKR*YLHTI*GR YSFSGTQRSVGHQRRRKWIPLESQDRRADVTPAP PQPGSQRGTPGGAWKR*KIFMAVSTEMDTYAHV AFFVLEKKTT*FSEGAT*NCGEWGEFGKKYVFI YKIYMWSFVGWGRDFSCYLT*ERLSAS*CQGSCL SAPRSPVTVTRPLSAAPAGDSGFQSFPRVFGSD QILSSLGDCFLSELSFSQGRVFFYTYQMEIAAS PSFISKRFTLNGVKRCLANQQLWLLVWSIFQSDI GFVCSEQS*NICSGLKKPSGLCGQLHRMNAHAD RPSVYFCIILVSFSDHDGQYGD*NMSSVISLW* LPFANQAVTNTCETQSCLVFFRWNHPDICFHPAK PTSHLLAESSHCHSV*QLATASVFSGVQ*AHLS HCTLGWVHSPHSFHEPDLSRSSFRPLPVSPALL GHLDTWGKVRPVCPAFYKTSCCIVYSKDGSENLI LVPGGNSKLSLKNS*LKIGPRL*GLKGTRVFFF FFFFFFF*MEFLFAQAGVQWRHLGSLQPLPPRF KRFSCLSLLSSWDHRRLPPHPANFLYF**RQGFT MLARLVSNS*PQAIHPPRPPKVLGLQA*ATTPN WDQGFLFFDGGEISL*STRFSS*NHLMPDY*TY SS*TQEHFNFSLIYKVTSAAYAYDKVAVCILMAI RCYKLLASKVRS*RDRCSSKVTVMLPKHKTAKI LLCCYECLPSALFYHLICAH*LLTVASARAKQL T**DHLVNLFT*CQASSHVFFSVCAYTGVKQFFS ILN*AFFLIYSRRDM*ISSQSFCDDLLSLAGQV VCLCANQTFFTQCNRFV*LLVSFYDLFAF*KIG K*SKYIF

Frame 2

GRAARRVRSFELR*HRGLGTRTPASQLRSLRSE SFVPEPSMNGYAEFPPSPSNPTKEPVEPQPSQV PLQEDVDMSSGSSGHETNENCSTGRDSQGSDCD DSGKELGMLVEPPDARQSPDTFSLMMAKSEHNPS TSGCSSDQSSKVDTHKELIKTLKELKVHLPADK KAKGKASTLATLKYALRSVKQVKANEEYYQLLM SSEGHPCGADVPSYTVEEMESVTSEHIVKNADMF AVAVSLVSGKILYISDQVASIFHCKRDAFSDAK FVEFLAPHDVGVFHSFTSPYKLPLWSMCSGADS FTQECMEEKSFFCRVSVRKSHENEIRYHPFRMTP YLVKVRDQQGAESQLCCLLLAERVHSGYEAPRI PPEKRIFTTTHTPNCLFQDVDERAVPLLGYLPQ DLIETPVLVQLHPSDRPLMLAIHKKILQSGGQPF DYSPIRFRARNGEYITLDTSWSSFINPWSRKIS FIIGRHKVRVGPLNEDVFAAHPCTEEKALHPSI QELTEQIHRLLLQPVPHSGSSGYGSLGSNGSHEH LMSQTSSSDSNGHEDSRRRRAEICKNGNKTKNR SHYSHESGEQKKKSVTEMQTNPPAEKKAVPAME KDSLGVSFPEELACKNQPTCSYQQISCLDSVIRY LESCNEAATLKRKCEFPANVPALRSSDKRKATV SPGPHAGEAEPPSRVNSRTGVGTHLTSLALPGK AESVASLTSQCSYSSTIVHVGDKKPQPELEMVED AASGPESLDCLAGPALACGLSQEKEPFKKLGLT KEVLAAHTQKEEQSFLQKFKEIRKLSIFQSHCH YYLQERSKGQPSERTAPGLRNTSGIDSPWKKTGK NRKLKSKRVKPRDSSESTGSGGPVSARPPLVGL NATAWSPSDTSQSSCPAVPFPAPVPAAYSLPVF PAPGTVAAPPAPPHASFTVPAVPVDLQHQFAVQP PPFPAPLAPVMAFMLPSYSFPSGTPNLPQAFFP SQPQFPSHPTLTSEMASASQPEFPSRTSIPRQP CACPATRATPPSAMGRASPPLFQSRSSSPLQLNL LQLEEAPEGGTGAMGTTGATETAAVGADCKPGT SRDQQPKAPLTRDEPSDTQNSDALSTSSGLLNL LLNEDLCSASGSAASESLGSGSLGCDASPSGAGS SDTSHTSKYFGSIDSSENNHKAKMNTGMEESEH FIKCVLQDPIWLLMADADSSVMMTYQLPSRNLE AVLKEDREKLKLLQKLQPRFTESQKQELREVHQW MQTGGLPAAIDVAECVYCENKEKGNICIPYEED IPSLGLSEVSDTKEDENGSPLNHRIEEQT*PLP HLSPAASEVHQVVLGRDERSSWLFPLKWTHMLML LFLF*KKKQHSFLKGRLKTVESGESSERNMFLY IKYICGVLWDGEEILVVI*LEKD*APLSVREVA SVLPEVL*L*RDLCLLHQLGTLASRAFPGCLDQI KFCPLLGTAFYLNYHLVKVECFFIHTKWR*QPL LVLFQNVSH*MV*SVVWQTNSFGFWCGQYFSLT *VLFVVNKVETFALD*RSLVVCVANSIG*MHTQT DPLYISALFLSPFQTMMANMEIKICHQSSLYGD FPLQTRL*PTHVRPSPVWFSSVGTTQTSASTQP SPHHISWPRAATATQSDSLRLHLYFQGCSELTSP TAPWVGCTALILFMSPTSLGAASGLCQCPQHF* VIWTLGEK*GQSARLFTKPHVALYIPKMVQKI* YWSLVEIQSYH*RTVDLKLDQDYEA*KGPGFSFF FFFFFFFRWSFFLPRLECSGAILAHCNLCLPGS SDSPASAS*VAGTTGDCHHTQLIFCIFSRDRVS PCWPGWSRTPDLKRSTHLGLPKCWDYRREPPRPT GTRVFCFLMEVKSLCNPLGFHRKTILCLTIKPI LHKHKNTLIFR*FTK*HQLPMPMIR*QSAFLWP LDVTNSLPLKSDHEGIGVHLRLQLCYRNTKLPKS YSAVMNVYHQHYFII*YVLTDC*L*LQRVPSS* LNRIIL*ICLRDAKHQVMFSLVCVLTQVLNSFS LF*TEPSF*YIPEEICK*ALRVSVMIC*ALLDKW FVCVQTKLSLPSAIDLFDCLCLFMTCLPFRKLV NKASIF