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Sequences

Sequence NM_199454

GACAATGCTGGGGAGATGAAGATAGTGTGTGGCTGCTTCTGGACTCAAGGAGGAGGAGAGAGATTCCGCGAGCCGACACCATGCGATCCAAGGCGAGGGC GAGGAAGCTAGCCAAAAGTGACGGTGACGTTGTAAATAATATGTATGAGCCCAACCGGGACCTGCTGGCCAGCCACAGCGCGGAGGACGAGGCCGAGGAC AGTGCCATGTCGCCCATCCCCGTGGGGCCACCGTCCCCCTTCCCCACCAGCGAGGACTTCACCCCCAAGGAGGGCTCGCCGTACGAGGCCCCTGTCTACA TTCCTGAAGACATTCCGATCCCAGCAGACTTCGAGCTCCGAGAGTCCTCCATCCCAGGGGCTGGCCTGGGGGTCTGGGCCAAGAGGAAGATGGAAGCCGG GGAGAGGCTGGGCCCCTGCGTGGTGGTGCCCCGGGCGGCGGCAAAGGAGACAGACTTCGGATGGGAGCAAATACTGACGGACGTGGAAGTGTCGCCCCAG GAAGGCTGCATCACAAAGATCTCCGAAGACCTGGGCAGTGAGAAGTTCTGCGTGGATGCAAATCAGGCGGGGGCTGGCAGCTGGCTCAAGTACATCCGTG TGGCGTGCTCCTGCGATGACCAGAACCTCACCATGTGTCAGATCAGTGAGCAGATTTACTATAAAGTCATTAAGGACATTGAGCCAGGTGAGGAGCTGCT GGTGCACGTGAAGGAAGGCGTCTACCCCCTGGGCACAGTGCCGCCCGGCCTGGACGAGGAGCCCACGTTCCGCTGTGACGAGTGTGACGAACTCTTCCAG TCCAAGCTGGACCTGCGGCGCCATAAGAAGTACACGTGTGGCTCAGTGGGGGCTGCGCTCTACGAGGGCCTGGCTGAGGAGCTCAAGCCCGAGGGCCTTG GCGGTGGCAGCGGCCAAGCCCACGAGTGCAAGGACTGCGAGCGGATGTTCCCCAACAAGTACAGCCTGGAGCAGCACATGGTCATCCACACGGAGGAGCG CGAGTACAAATGCGACCAGTGTCCCAAGGCCTTCAACTGGAAGTCCAACCTCATCCGCCACCAGATGTCCCACGACAGCGGCAAACGCTTCGAATGTGAA AACTGCGTGAAGGTGTTCACGGACCCCAGCAACCTTCAGCGGCACATCCGCTCGCAGCACGTGGGCGCTCGGGCCCACGCCTGCCCCGACTGCGGGAAGA CCTTCGCCACGTCCTCCGGCCTCAAGCAGCACAAGCATATCCACAGCACGGTGAAGCCTTTCATATGTGAGGTCTGCCACAAGTCCTACACGCAGTTCTC CAACCTGTGCCGGCACAAGCGGATGCACGCCGACTGCCGCACGCAGATCAAGTGCAAGGACTGTGGCCAGATGTTCAGCACTACCTCCTCCCTCAACAAG CACCGGCGCTTCTGCGAGGGCAAGAACCATTACACGCCGGGCGGCATCTTTGCCCCGGGCCTGCCCTTGACCCCCAGCCCCATGATGGACAAGGCAAAAC CCTCCCCCAGCCTCAATCACGCCAGCCTGGGCTTCAACGAGTACTTTCCCTCCAGGCCGCACCCGGGGAGCCTGCCCTTCTCCACGGCGCCTCCCACGTT CCCCGCACTCACCCCCGGCTTCCCGGGCATCTTCCCTCCATCCTTGTACCCCCGGCCGCCTCTGCTACCTCCCACATCGCTGCTCAAGAGCCCCCTGAAC CACACCCAGGACGCCAAGCTCCCCAGTCCCCTGGGGAACCCAGCCCTGCCCCTGGTCTCCGCCGTCAGCAACAGCAGCCAGGGCACGACGGCAGCTGCGG GGCCCGAGGAGAAGTTCGAGAGCCGCCTGGAGGACTCCTGTGTGGAGAAGCTGAAGACCAGGAGCAGCGACATGTCGGACGGCAGTGACTTTGAGGACGT CAACACCACCACGGGGACCGACCTGGACACGACCACGGGGACGGGCTCGGACCTGGACAGCGACGTGGACAGCGACCCTGACAAGGACAAGGGCAAGGGC AAGTCCGCCGAGGGCCAGCCCAAGTTTGGGGGCGGCTTGGCGCCCCCGGGGGCCCCGAACAGCGTGGCCGAGGTGCCTGTCTTCTATTCCCAGCACTCAT TCTTCCCGCCACCCGACGAGCAGCTGCTGACTGCAACGGGCGCCGCCGGGGACTCCATCAAGGCCATCGCATCCATTGCCGAGAAGTACTTTGGCCCCGG CTTCATGGGGATGCAGGAGAAGAAGCTGGGCTCGCTCCCCTACCACTCGGCGTTCCCCTTCCAGTTCCTGCCCAACTTCCCCCACTCCCTTTACCCCTTC ACGGACCGAGCCCTCGCCCACAACTTGCTGGTCAAGGCCGAGCCAAAGTCACCCCGGGACGCCCTCAAGGTGGGCGGCCCCAGTGCCGAGTGCCCCTTTG ATCTCACCACCAAGCCCAAAGACGTGAAGCCCATCCTGCCCATGCCCAAGGGCCCCTCGGCCCCCGCATCCGGCGAGGAGCAGCCGCTGGACCTGAGCAT CGGCAGCCGGGCCCGTGCCAGCCAAAACGGCGGCGGGCGGGAGCCCCGCAAGAACCACGTCTATGGGGAACGCAAGCTGGGCGCCGGCGAGGGGCTGCCC CAGGTGTGCCCGGCGCGGATGCCCCAGCAGCCCCCGCTCCACTACGCCAAGCCCTCGCCCTTCTTCATGGACCCCATCTACAGGGTAGAAAAGCGGAAGG TCACAGACCCCGTGGGAGCCCTGAAGGAGAAGTACCTGCGGCCGTCCCCGCTGCTCTTCCACCCCCAGATGTCAGCCATAGAGACCATGACAGAGAAGCT GGAGAGCTTTGCAGCCATGAAGGCGGACTCGGGCAGCTCCCTGCAGCCCCTCCCCCACCACCCCTTCAACTTCCGGTCCCCACCCCCAACGCTCTCCGAC CCCATCCTCAGGAAGGGCAAGGAGCGATACACGTGCAGGTACTGTGGGAAGATCTTCCCCAGATCAGCCAATCTCACCAGACACCTGAGGACGCACACTG GGGAGCAGCCGTACAGGTGTAAGTACTGCGACCGCTCCTTCAGCATCTCTTCGAACCTCCAGCGGCACGTCCGGAACATCCACAACAAGGAGAAGCCTTT CAAGTGCCACCTGTGCAACCGCTGCTTCGGGCAGCAGACCAACCTGGACCGGCACCTCAAGAAGCACGAGCACGAGAACGCACCAGTGAGCCAGCACCCC GGGGTCCTCACGAACCACCTGGGGACCAGCGCGTCCTCTCCCACCTCAGAGTCGGACAACCACGCACTTTTAGACGAGAAAGAAGACTCTTATTTCTCGG AAATCAGAAACTTTATTGCCAATAGTGAGATGAACCAAGCATCAACGCGAACAGAGAAACGGGCGGACATGCAGATCGTGGACGGCAGTGCCCAGTGTCC AGGCCTAGCCAGTGAGAAGCAGGAGGACGTGGAGGAGGAGGACGACGATGACCTGGAGGAGGACGATGAGGACAGCCTGGCCGGGAAGTCGCAGGATGAC ACCGTGTCCCCCGCACCCGAGCCCCAGGCCGCCTACGAGGATGAGGAGGATGAGGAGCCAGCCGCCTCCCTGGCCGTGGGCTTTGACCACACCCGAAGGT GTGCTGAGGACCACGAAGGCGGTCTGTTAGCTTTGGAGCCGATGCCGACTTTTGGGAAGGGGCTGGACCTCCGCAGAGCAGCTGAGGAAGCATTTGAAGT TAAAGATGTGCTTAATTCCACCTTAGATTCTGAGGCTTTAAAACATACACTGTGCAGGCAGGCTAAGAACCAGGGTTCTCTGGACGCTTGGTTGAAGGTC ACTGGAGCCACGTCGGAGTCTGGAGCATTTCACCCCATCAACCACCTCTGACGGGCTGGGCAGCCGGGGGCCGGTGGCCAGAGCGAGGGCACCAGCCACG AAGGACGGAGGCGGGCGGGGCCCCGGAGAACCCTGTCCCTGCGTGTGGCCACTCCTCAGCATCCTCCCCACCCACCATGGTTCATTCCGACTTTTCCAAT GGAAACTCAGATCCCAAAAGTCCCTAAAGCAGTCGTAGAGTCTCACCATCTCCAAGGATTGGTCTTGAGAACACTGTTCAGTGACGGCCATGCAGGTGGC CGTCCAAAGACAGCCAACGGAGCTGCCTCGCAGAATCAGCCAGTGGGCAGGTGGACGCTCTGCTGAGACAGAAGCTGGTGGCCACTGCCGGGTGCCCGCG TGGGGTCGCGGAAGGGAATGGATAGACTGGTGTGCTCAAAAGAGAGAGATCACTCAAATGATTTTTATAATGAAATGACAAGAATAACCCTTTTGGTAAC CGTATTGACTGCAGAGTCTATTTAAGCATGTGGTTTTAAAAATAGACAGTATTTTTTAAAAATCAAAAAATGACTTGCAAATTGTTTTTTAAAAGTAATT TTGCATTGCTTTGAAATTTGAGCTCATTTGCAAACCCGAGTCTGCCTGGGAACCCGCACTGTGCCTGGGTGTATTCTTTATACTGTAGATAATGGAGAAA TTTTCTATCTCTGTCCCTATTTGTATAAGCCAAGGTGATGCTGGGTGCCCCGAGGCAGAACAAGAGGCGCGGGGCCACACCCGTGAACCATGCAGACGGC CGAAGAAGTCTTAGGCAGGGCGCCCTGGGCTGCAGGCCTGCCCGAGGCTGGGATGGGAAGTGTGCCTGCCCTCGTGTGACATGGAATTGGTGTCAGGACC GCCACGTGGCCTTCAGAGGAATCCACAGGTCCCCACCCAAGATCCCTCAATTATATGGGGAAGTCGAGGGCCTGTGGCTTGGATCCGCCATGCAGAGATG TGGCCGGGCACCCATCTTCCTTCCCTCCTCTGTCCCTGCCTCGGCCACCCCACGCGGGAACCCAGCGCCGTCCTCTGAAGGCAGGGCCTTGGCCACGTCC TGGGTCTCCCACCTCCCACCTGACCCCAGCGGCTCCGGTGTCCTCCACGTGGCTGCCCTGGGGAGCAATCCCAGCGGATCGCTCCGGGCCACCAAGCCGC ACCTGTGCCTGAGACTCCGGATGGACGACACAGTCGTCACGTCGCTCTTCCTGCGGGTTCTTGGCGAGACACAGCTTGAGAACAGAAGGGCGTCGGGGGA ACCTGCCGCAAGGAGCAGAGACAGCACAGCCCCCCGGGCCCAGCCGCCTCCCTCTCTTGGGACGCAACTTCTTCCCCACTCGGATGGGCTTTAAATTATT CCCATAGGGGCCAATTTCAAATAATAATTTTTTTCCCTGATGGAATTTACCTTAATCTGTATATAACTTGTAATTTTTTCTAATTCATTTCTTTTCTTAT TTTATTTCCTCCTTAACAGTATTTTTGGCATTAGACATTCTTATTGTGAAGAAATAATGTTAATATAAGTATCTGGTGAAGGACCAAAACCGTGTGATAA GGTTGTGTGTCGTGTGGGAGTGGGGCGATTTTTTATGTGCCAAATACCCCCGTCCCCCCCATGAATCCTGCTGTCCCTGCTGCCGTTTACCAGACAATCA TATGTTTTTGTTAAATTTGCGTTTCAGTTACATTTGCATTTAAGACAAGTGTTCTATTTATTTCTTGTATTGTTTGGAAGAAAAAATGATGATAGAGTCC CAAAAAGAAGAGAAAAAAAATGCCCAAGTTGCCCTTTAAAAAAAAAGAGCGTAAATACAAACAGGAGTGGTGCAAGCCGCCTTGGTGTGGGTTTGTGTCA CGTGTGGACATCTCCTCAGGCTTTGTGTCACGCGTGGACATCTCCTCAGGCTGTCCCCAGCGGTGACGGGAGGTGTCCTGGCTGCTCCAGGACAAAAGAC AATCGTCTCTGTGGGTGCCGGGTGGTCCAGGCTTGCACTGAAGACGTGCCACGGGGAGGCTCCTGCAGGAGGCTCAACCCGACGGATCACAGTGAAAGGG ATTCCTCCCACGCCAGATCTGCACAACGAGGCAAGACAGGACCCACCTGTGCGTGCGCTGGGGCCATGGGGTGGCCCCGCCGGGGCAGCGGGGGAGCTGC CTGCAGAAGAGCCAGCTGGCGTGTCGGGAAGGATCCAGGATCTGCAAACACAACTGCTCAGGCCTTCTCACGCGTTTCCACAACATCCCCTGGGTCAGAC CCACCAGGTACCCCGTAGGAATTTCCAGTTTCCCTTGATCTAGATGGGATTCTTATAAAAATTCAACCTCAGACATAAACACCCCATTTCTGTAAACCCA AATTATATGGTTTCTTCTGCGAAAGAGTAAGGTGTGTGCTTTTTTTTTTTTGCAATATGACCCCGTCTCTCTGAAGTGGGACATTCGGACGGATGGAGCC CTCAGCGTGTCTTTTCAGCAGGAGCAGAACCGATGAGAGCCGCCCTTACCGTTGGTCTCCGGATCCCCCAGTCCCATCCCGCCGTTTTCGGCTGTCTTCC TAACCGTCCTGTCTTCTCTTGGCGCTCTTTCCTTCCACCTTTCCCAAGAGTCCTGGTTGCACGTTTTAAGTCATATATTTTCGTCCCCCTGAAAATGATG GCAAGCCCAGTTTCTCCTGAGCATTCAGACCCCCAGGCCCCAGCACTTGGCGTTTTCAGGAGGCCCTGTTCTTAGAGCCCCTGACAAAGGCAGCACTTAT TTCCTGGGCTGGTGCGCCCCAAAACACGGCCCCGACACTTAGTGTGGCCCCAGGCCCCAGCGAGCCTCGCCCTCCCAGTTTTGCTCTGCCCAGCAGTGTT GGTGCCCAGAGATGACAAGGGCCAGGGAGCCTGGCCCGGGTGTGAGAATTCAGAGATTCTGGCCTCCAGCTGTCACCACACCGTAACGGGGCCATGTAAC TGTGCAGCATGGACAGGGATGCGACGGGGCAGCTGGCTGTGTCCATGGCCAGGTGGCCAGGGTCAGGGCTGCAAGCCAGGGGTCCAGGGCCCTTCCGTTC AGCCCAAATGCTGCCCCAATGCTAACTCCTTGGATTGTCAACCCCCATCCCCCAAATGGAAATTCCGAAGGAGGCCTCCTCGCACCTGCCCTCCGCTGCT CCTCAGACCCCAGCCCCCAGCGAGCCGACGTCCCCACCCGTTCCTGCTCTCATCCCCAGGTTGGGCACGTGGGGTTCCTCCTCTGTGGGCCTGGCAGACC CTTCATGAGTGGGACCCAAGATATCACTGACTTCAACCCAGAGGATCGAGCCCCTGCACCCTGCCTGGGGCCCTGGGGTGTGGAGCAGTGGCTGGGGTGG GCGTGGTGTGGCCTGAGAGACTGCCCAGCTGGAGAGGCCTTCCTTTACAAGGCCACGCGTGCAGCTGTCCCATCCAGACCCCGACTGGCCAAGACCTCCA CGTCCCCAGAGTCCAGCCCTGGAAATTCCAAGGGCCCTGGCGTCCTCTGCCTTCCCCGCTTCCCCATGAGCGTCTGCAAAACACTTGCCTGAATACATAT CACGTATTTTAGACTCGAAGCCTCAAAGCACTGGATTGTGGTCCCCTGCCCCCTCTGTCCCGTCCCCCTGCCCAAGTGACTGAAACCTACTGAGCTATAT TCACTGTGCTGTCCTAGGGGGAGGGAGAGCAGAGCTCGCCCCTGCACTGCAGCCTTGTGGGGGAGGGCAAGGCTCTCCTCCCAGCCAGGGACGCCAGGAC ATAGCTGCTCCTGGTCAGTGGAGGTCAGCCGGGTATCAAAAGCCATGAAACTGTGTCTCTGTAGCAATGAGTGATACTGTGACAAAACCATCCTTGCATT CTTCCTAGAAGAGTTCCTCTGCTCCTTCCATTCCATTTTTGTGTTTGTTTTGTTCTTTTCTGTCACTGATCCGTATTACCACTTTTGGAAAAAAATAAAT AAATAAATAAATAAAAGGCAGCTTGAGTTTCCAAACGTGTGATTCACTTGTGAACAAAAGTCATTCTAACAATTGCCTTCAGCGTCACGTGCATTGCCAC TGCGCTTTCGGCACGAGGGATGCTGAGCCCTGGTGTCAGAGTCGTAATTTAAAGCGTGTGTGTATATGGACTTTGTCCCTTAAGGTCGATATAAAGAATC CTCGCAGAATCACAGACCTGTGCCGCCCGCCACCTTCTGCCATTGTTACATTACAGATTTGGTTTAGTTTTGTTTTGTTTTGTTTTTTCTTTTAGAACTG TATAGTATTGAAAAAGAAATCAAATGTAAATGTCTGGTTTTCATATAATGTTTAAAAAGACCATTGAGAAGGAGGCTGGCGCTCGCCCCATGTCCCCCTT GATTGTAAATTGCTTCTGTTCTGTTTATAAGTAAACTGTGCATGACTCCTGCTTAGCGGTCATTATCGTGTCTGTTGGTGAAATTTTTATTAAAAGGAAA ATTCTGTAGATGCACTTATTGAATATGTGATTAGGATCTACGTCTGAGACTAGGAGTCCTGAACTGCTGACGCGAAAGAGGCGCAGTTCCCAATTAATAC GGAAATCGCTGTGGGAGAAGAATGAAATAAGACGTGAAGTGTAGGAAATCATGAAAAGAACAATTTTGCAAATTGCATTCTGATGCTTGTGATGAACACA AATGTACTTGTGTAGAGACATTTCCTTAAGAGAAAGCCTAGGAGAAGCCGATTTGGAGGTTAATGCTGTAGAATAGGACTGTATACCAAATGTAATCTTT CCAATGCTCCAATGAATTTATACATGAGATTGATATGCAATAAATCTGTGTGCTTTTCTAA

refseq_PRDM16.F1 (forward primer)
refseq_PRDM16.R1 (reverse primer)
Alternative acceptor

Frame 0

DNAGEMKIVCGCFWTQGGGERFREPTPCDPRRG RGS*PKVTVTL*IICMSPTGTCWPATARRTRPRT VPCRPSPWGHRPPSPPARTSPPRRARRTRPLST FLKTFRSQQTSSSESPPSQGLAWGSGPRGRWKP GRGWAPAWWCPGRRQRRQTSDGSKY*RTWKCRPR KAASQRSPKTWAVRSSAWMQIRRGLAAGSSTSV WRAPAMTRTSPCVRSVSRFTIKSLRTLSQVRSC WCT*RKASTPWAQCRPAWTRSPRSAVTSVTNSSS PSWTCGAIRSTRVAQWGLRSTRAWLRSSSPRAL AVAAAKPTSARTASGCSPTSTAWSSTWSSTRRS ASTNATSVPRPSTGSPTSSATRCPTTAANASNVK TA*RCSRTPATFSGTSARSTWALGPTPAPTAGR PSPRPPASSSTSISTAR*SLSYVRSATSPTRSS PTCAGTSGCTPTAARRSSARTVARCSALPPPSTS TGASARARTITRRAASLPRACP*PPAP*WTRQN PPPASITPAWASTSTFPPGRTRGACPSPRRLPR SPHSPPASRASSLHPCTPGRLCYLPHRCSRAP*T TPRTPSSPVPWGTQPCPWSPPSATAARARRQLR GPRRSSRAAWRTPVWRS*RPGAATCRTAVTLRT STPPRGPTWTRPRGRARTWTATWTATLTRTRARA SPPRASPSLGAAWRPRGPRTAWPRCLSSIPSTH SSRHPTSSC*LQRAPPGTPSRPSHPLPRSTLAP ASWGCRRRSWARSPTTRRSPSSSCPTSPTPFTPS RTEPSPTTCWSRPSQSHPGTPSRWAAPVPSAPL ISPPSPKT*SPSCPCPRAPRPPHPARSSRWT*A SAAGPVPAKTAAGGSPARTTSMGNASWAPARGCP RCARRGCPSSPRSTTPSPRPSSWTPSTG*KSGR SQTPWEP*RRSTCGRPRCSSTPRCQP*RP*QRS WRALQP*RRTRAAPCSPSPTTPSTSGPHPQRSPT PSSGRARSDTRAGTVGRSSPDQPISPDT*GRTL GSSRTGVSTATAPSASLRTSSGTSGTSTTRRSL SSATCATAASGSRPTWTGTSRSTSTRTHQ*ASTP GSSRTTWGPARPLPPQSRTTTHF*TRKKTLISR KSETLLPIVR*TKHQREQRNGRTCRSWTAVPSV QA*PVRSRRTWRRRTTMTWRRTMRTAWPGSRRMT PCPPHPSPRPPTRMRRMRSQPPPWPWALTTPEG VLRTTKAVC*LWSRCRLLGRGWTSAEQLRKHLK LKMCLIPP*ILRL*NIHCAGRLRTRVLWTLG*RS LEPRRSLEHFTPSTTSDGLGSRGPVARARAPAT KDGGGRGPGEPCPCVWPLLSILPTHHGSFRLFQ WKLRSQKSLKQS*SLTISKDWS*EHCSVTAMQVA VQRQPTELPRRISQWAGGRSAETEAGGHCRVPA WGRGREWIDWCAQKREITQMIFIMK*QE*PFW* PY*LQSLFKHVVLKIDSIF*KSKNDLQIVF*K*F CIALKFELICKPESAWEPALCLGVFFIL*IMEK FSISVPICISQGDAGCPEAEQEARGHTREPCRR PKKS*AGRPGLQACPRLGWEVCLPSCDMELVSGP PRGLQRNPQVPTQDPSIIWGSRGPVAWIRHAEM WPGTHLPSLLCPCLGHPTREPSAVL*RQGLGHV LGLPPPT*PQRLRCPPRGCPGEQSQRIAPGHQAA PVPETPDGRHSRHVALPAGSWRDTA*EQKGVGG TCRKEQRQHSPPGPAASLSWDATSSPLGWALNY SHRGQFQIIIFFPDGIYLNLYITCNFF*FISFLI LFPP*QYFWH*TFLL*RNNVNISIW*RTKTV** GCVSCGSGAIFYVPNTPVPPMNPAVPAAVYQTI ICFC*ICVSVTFAFKTSVLFISCIVWKKK***SP KKKRKKMPKLPFKKKERKYKQEWCKPPWCGFVS RVDISSGFVSRVDISSGCPQR*REVSWLLQDKR QSSLWVPGGPGLH*RRATGRLLQEAQPDGSQ*KG FLPRQICTTRQDRTHLCVRWGHGVAPPGQRGSC LQKSQLACREGSRICKHNCSGLLTRFHNIPWVR PTRYPVGISSFP*SRWDSYKNSTSDINTPFL*TQ IIWFLLRKSKVCAFFFLQYDPVSLKWDIRTDGA LSVSFQQEQNR*EPPLPLVSGSPSPIPPFSAVF LTVLSSLGALSFHLSQESWLHVLSHIFSSP*K*W QAQFLLSIQTPRPQHLAFSGGPVLRAPDKGSTY FLGWCAPKHGPDT*CGPRPQRASPSQFCSAQQC WCPEMTRAREPGPGVRIQRFWPPAVTTP*RGHVT VQHGQGCDGAAGCVHGQVARVRAASQGSRALPF SPNAAPMLTPWIVNPHPPNGNSEGGLLAPALRC SSDPSPQRADVPTRSCSHPQVGHVGFLLCGPGRP FMSGTQDITDFNPEDRAPAPCLGPWGVEQWLGW AWCGLRDCPAGEAFLYKATRAAVPSRPRLAKTS TSPESSPGNSKGPGVLCLPRFPMSVCKTLA*IHI TYFRLEASKHWIVVPCPLCPVPLPK*LKPTELY SLCCPRGRESRARPCTAALWGRARLSSQPGTPG HSCSWSVEVSRVSKAMKLCLCSNE*YCDKTILAF FLEEFLCSFHSIFVFVLFFSVTDPYYHFWKKIN K*INKRQLEFPNV*FTCEQKSF*QLPSASRALP LRFRHEGC*ALVSES*FKACVYMDFVP*GRYKES SQNHRPVPPATFCHCYITDLV*FCFVLFFLLEL YSIEKEIKCKCLVFI*CLKRPLRRRLALAPCPP *L*IASVLFISKLCMTPA*RSLSCLLVKFLLKGK FCRCTY*ICD*DLRLRLGVLNC*RERGAVPN*Y GNRCGRRMK*DVKCRKS*KEQFCKLHSDACDEH KCTCVETFP*EKA*EKPIWRLML*NRTVYQM*SF QCSNEFIHEIDMQ*ICVLF*

Frame 1

TMLGR*R*CVAASGLKEEERDSASRHHAIQGEG EEASQK*R*RCK*YV*AQPGPAGQPQRGGRGRG QCHVAHPRGATVPLPHQRGLHPQGGLAVRGPCLH S*RHSDPSRLRAPRVLHPRGWPGGLGQEEDGSR GEAGPLRGGAPGGGKGDRLRMGANTDGRGSVAP GRLHHKDLRRPGQ*EVLRGCKSGGGWQLAQVHPC GVLLR*PEPHHVSDQ*ADLL*SH*GH*AR*GAA GAREGRRLPPGHSAARPGRGAHVPL*RV*RTLP VQAGPAAP*EVHVWLSGGCALRGPG*GAQARGPW RWQRPSPRVQGLRADVPQQVQPGAAHGHPHGGA RVQMRPVSQGLQLEVQPHPPPDVPRQRQTLRM* KLREGVHGPQQPSAAHPLAARGRSGPRLPRLRED LRHVLRPQAAQAYPQHGEAFHM*GLPQVLHAVL QPVPAQADARRLPHADQVQGLWPDVQHYLLPQQ APALLRGQEPLHAGRHLCPGPALDPQPHDGQGKT LPQPQSRQPGLQRVLSLQAAPGEPALLHGASHV PRTHPRLPGHLPSILVPPAASATSHIAAQEPPE PHPGRQAPQSPGEPSPAPGLRRQQQQPGHDGSCG ARGEVREPPGGLLCGEAEDQEQRHVGRQ*L*GR QHHHGDRPGHDHGDGLGPGQRRGQRP*QGQGQG QVRRGPAQVWGRLGAPGGPEQRGRGACLLFPALI LPATRRAAADCNGRRRGLHQGHRIHCREVLWPR LHGDAGEEAGLAPLPLGVPLPVPAQLPPLPLPL HGPSPRPQLAGQGRAKVTPGRPQGGRPQCRVPL* SHHQAQRREAHPAHAQGPLGPRIRRGAAAGPEH RQPGPCQPKRRRAGAPQEPRLWGTQAGRRRGAA PGVPGADAPAAPAPLRQALALLHGPHLQGRKAEG HRPRGSPEGEVPAAVPAALPPPDVSHRDHDREA GELCSHEGGLGQLPAAPPPPPLQLPVPTPNALR PHPQEGQGAIHVQVLWEDLPQISQSHQTPEDAHW GAAVQV*VLRPLLQHLFEPPAARPEHPQQGEAF QVPPVQPLLRAADQPGPAPQEARARERTSEPAP RGPHEPPGDQRVLSHLRVGQPRTFRRERRLLFLG NQKLYCQ**DEPSINANRETGGHADRGRQCPVS RPSQ*EAGGRGGGGRR*PGGGR*GQPGREVAG* HRVPRTRAPGRLRG*GG*GASRLPGRGL*PHPKV C*GPRRRSVSFGADADFWEGAGPPQSS*GSI*S *RCA*FHLRF*GFKTYTVQAG*EPGFSGRLVEG HWSHVGVWSISPHQPPLTGWAAGGRWPERGHQPR RTEAGGAPENPVPACGHSSASSPPTMVHSDFSN GNSDPKSP*SSRRVSPSPRIGLENTVQ*RPCRW PSKDSQRSCLAESASGQVDALLRQKLVATAGCPR GVAEGNG*TGVLKRERSLK*FL**NDKNNPFGN RIDCRVYLSMWF*K*TVFFKNQKMTCKLFFKSN FALL*NLSSFANPSLPGNPHCAWVYSLYCR*WRN FLSLSLFV*AKVMLGAPRQNKRRGATPVNHADG RRSLRQGALGCRPARGWDGKCACPRVTWNWCQD RHVAFRGIHRSPPKIPQLYGEVEGLWLGSAMQRC GRAPIFLPSSVPASATPRGNPAPSSEGRALATS WVSHLPPDPSGSGVLHVAALGSNPSGSLRATKP HLCLRLRMDDTVVTSLFLRVLGETQLENRRASGE PAARSRDSTAPRAQPPPSLGTQLLPHSDGL*II PIGANFK**FFSLMEFTLICI*LVIFSNSFLFL FYFLLNSIFGIRHSYCEEIMLI*VSGEGPKPCDK VVCRVGVGRFFMCQIPPSPP*ILLSLLPFTRQS YVFVKFAFQLHLHLRQVFYLFLVLFGRKNDDRV PKRREKKCPSCPLKKKSVNTNRSGASRLGVGLCH VWTSPQALCHAWTSPQAVPSGDGRCPGCSRTKD NRLCGCRVVQACTEDVPRGGSCRRLNPTDHSER DSSHARSAQRGKTGPTCACAGAMGWPRRGSGGAA CRRASWRVGKDPGSANTTAQAFSRVSTTSPGSD PPGTP*EFPVSLDLDGILIKIQPQT*TPHFCKP KLYGFFCERVRCVLFFFCNMTPSL*SGTFGRMEP SACLFSRSRTDESRPYRWSPDPPVPSRRFRLSS *PSCLLLALFPSTFPKSPGCTF*VIYFRPPEND GKPSFS*AFRPPGPSTWRFQEALFLEPLTKAALI SWAGAPQNTAPTLSVAPGPSEPRPPSFALPSSV GAQR*QGPGSLARV*EFRDSGLQLSPHRNGAM* LCSMDRDATGQLAVSMARWPGSGLQARGPGPFRS AQMLPQC*LLGLSTPIPQMEIPKEASSHLPSAA PQTPAPSEPTSPPVPALIPRLGTWGSSSVGLAD PS*VGPKISLTSTQRIEPLHPAWGPGVWSSGWGG RGVA*ETAQLERPSFTRPRVQLSHPDPDWPRPP RPQSPALEIPRALASSAFPASP*ASAKHLPEYI SRILDSKPQSTGLWSPAPSVPSPCPSD*NLLSYI HCAVLGGGRAELAPALQPCGGGQGSPPSQGRQD IAAPGQWRSAGYQKP*NCVSVAMSDTVTKPSLH SS*KSSSAPSIPFLCLFCSFLSLIRITTFGKK*I NK*IKGSLSFQTCDSLVNKSHSNNCLQRHVHCH CAFGTRDAEPWCQSRNLKRVCIWTLSLKVDIKN PRRITDLCRPPPSAIVTLQIWFSFVLFCFFF*NC IVLKKKSNVNVWFSYNV*KDH*EGGWRSPHVPL DCKLLLFCL*VNCA*LLLSGHYRVCW*NFY*KE NSVDALIEYVIRIYV*D*ES*TADAKEAQFPINT EIAVGEE*NKT*SVGNHEKNNFANCILMLVMNT NVLV*RHFLKRKPRRSRFGG*CCRIGLYTKCNL SNAPMNLYMRLICNKSVCFS

Frame 2

QCWGDEDSVWLLLDSRRRREIPRADTMRSKARA RKLAKSDGDVVNNMYEPNRDLLASHSAEDEAED SAMSPIPVGPPSPFPTSEDFTPKEGSPYEAPVY IPEDIPIPADFELRESSIPGAGLGVWAKRKMEAG ERLGPCVVVPRAAAKETDFGWEQILTDVEVSPQ EGCITKISEDLGSEKFCVDANQAGAGSWLKYIR VACSCDDQNLTMCQISEQIYYKVIKDIEPGEELL VHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGL GGGSGQAHECKDCERMFPNKYSLEQHMVIHTEER EYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECE NCVKVFTDPSNLQRHIRSQHVGARAHACPDCGK TFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFS NLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNK HRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAK PSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTF PALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAA GPEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDV NTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKG KSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHS FFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPG FMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPF TDRALAHNLLVKAEPKSPRDALKVGGPSAECPF DLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSI GSRARASQNGGGREPRKNHVYGERKLGAGEGLP QVCPARMPQQPPLHYAKPSPFFMDPIYRVEKRK VTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKL ESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSD PILRKGKERYTCRYCGKIFPRSANLTRHLRTHT GEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPF KCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHP GVLTNHLGTSASSPTSESDNHALLDEKEDSYFS EIRNFIANSEMNQASTRTEKRADMQIVDGSAQCP GLASEKQEDVEEEDDDDLEEDDEDSLAGKSQDD TVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRR CAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEV KDVLNSTLDSEALKHTLCRQAKNQGSLDAWLKV TGATSESGAFHPINHL*RAGQPGAGGQSEGTSH EGRRRAGPRRTLSLRVATPQHPPHPPWFIPTFPM ETQIPKVPKAVVESHHLQGLVLRTLFSDGHAGG RPKTANGAASQNQPVGRWTLC*DRSWWPLPGAR VGSRKGMDRLVCSKERDHSNDFYNEMTRITLLVT VLTAESI*ACGFKNRQYFLKIKK*LANCFLKVI LHCFEI*AHLQTRVCLGTRTVPGCILYTVDNGE IFYLCPYLYKPR*CWVPRGRTRGAGPHP*TMQTA EEVLGRAPWAAGLPEAGMGSVPALV*HGIGVRT ATWPSEESTGPHPRSLNYMGKSRACGLDPPCRD VAGHPSSFPPLSLPRPPHAGTQRRPLKAGPWPRP GSPTSHLTPAAPVSSTWLPWGAIPADRSGPPSR TCA*DSGWTTQSSRRSSCGFLARHSLRTEGRRG NLPQGAETAQPPGPSRLPLLGRNFFPTRMGFKLF P*GPISNNNFFP*WNLP*SVYNL*FFLIHFFSY FISSLTVFLALDILIVKK*C*YKYLVKDQNRVI RLCVVWEWGDFLCAKYPRPPHESCCPCCRLPDNH MFLLNLRFSYICI*DKCSIYFLYCLEEKMMIES QKEEKKNAQVAL*KKRA*IQTGVVQAALVWVCV TCGHLLRLCVTRGHLLRLSPAVTGGVLAAPGQKT IVSVGAGWSRLALKTCHGEAPAGGSTRRITVKG IPPTPDLHNEARQDPPVRALGPWGGPAGAAGEL PAEEPAGVSGRIQDLQTQLLRPSHAFPQHPLGQT HQVPRRNFQFPLI*MGFL*KFNLRHKHPISVNP NYMVSSAKE*GVCFFFFAI*PRLSEVGHSDGWS PQRVFSAGAEPMRAALTVGLRIPQSHPAVFGCLP NRPVFSWRSFLPPFPRVLVARFKSYIFVPLKMM ASPVSPEHSDPQAPALGVFRRPCS*SP*QRQHL FPGLVRPKTRPRHLVWPQAPASLALPVLLCPAVL VPRDDKGQGAWPGCENSEILASSCHHTVTGPCN CAAWTGMRRGSWLCPWPGGQGQGCKPGVQGPSV QPKCCPNANSLDCQPPSPKWKFRRRPPRTCPPLL LRPQPPASRRPHPFLLSSPGWARGVPPLWAWQT LHEWDPRYH*LQPRGSSPCTLPGALGCGAVAGV GVVWPERLPSWRGLPLQGHACSCPIQTPTGQDLH VPRVQPWKFQGPWRPLPSPLPHERLQNTCLNTY HVF*TRSLKALDCGPLPPLSRPPAQVTETY*AI FTVLS*GEGEQSSPLHCSLVGEGKALLPARDART *LLLVSGGQPGIKSHETVSL*Q*VIL*QNHPCI LPRRVPLLLPFHFCVCFVLFCH*SVLPLLEKNK *INK*KAA*VSKRVIHL*TKVILTIAFSVTCIAT ALSARGMLSPGVRVVI*SVCVYGLCPLRSI*RI LAESQTCAARHLLPLLHYRFGLVLFCFVFSFRT V*Y*KRNQM*MSGFHIMFKKTIEKEAGARPMSPL IVNCFCSVYK*TVHDSCLAVIIVSVGEIFIKRK IL*MHLLNM*LGSTSETRSPELLTRKRRSSQLI RKSLWEKNEIRREV*EIMKRTILQIAF*CL**TQ MYLCRDISLRESLGEADLEVNAVE*DCIPNVIF PMLQ*IYT*D*YAINLCAFL

Sequence NM_022114

GACAATGCTGGGGAGATGAAGATAGTGTGTGGCTGCTTCTGGACTCAAGGAGGAGGAGAGAGATTCCGCGAGCCGACACCATGCGATCCAAGGCGAGGGC GAGGAAGCTAGCCAAAAGTGACGGTGACGTTGTAAATAATATGTATGAGCCCAACCGGGACCTGCTGGCCAGCCACAGCGCGGAGGACGAGGCCGAGGAC AGTGCCATGTCGCCCATCCCCGTGGGGCCACCGTCCCCCTTCCCCACCAGCGAGGACTTCACCCCCAAGGAGGGCTCGCCGTACGAGGCCCCTGTCTACA TTCCTGAAGACATTCCGATCCCAGCAGACTTCGAGCTCCGAGAGTCCTCCATCCCAGGGGCTGGCCTGGGGGTCTGGGCCAAGAGGAAGATGGAAGCCGG GGAGAGGCTGGGCCCCTGCGTGGTGGTGCCCCGGGCGGCGGCAAAGGAGACAGACTTCGGATGGGAGCAAATACTGACGGACGTGGAAGTGTCGCCCCAG GAAGGCTGCATCACAAAGATCTCCGAAGACCTGGGCAGTGAGAAGTTCTGCGTGGATGCAAATCAGGCGGGGGCTGGCAGCTGGCTCAAGTACATCCGTG TGGCGTGCTCCTGCGATGACCAGAACCTCACCATGTGTCAGATCAGTGAGCAGATTTACTATAAAGTCATTAAGGACATTGAGCCAGGTGAGGAGCTGCT GGTGCACGTGAAGGAAGGCGTCTACCCCCTGGGCACAGTGCCGCCCGGCCTGGACGAGGAGCCCACGTTCCGCTGTGACGAGTGTGACGAACTCTTCCAG TCCAAGCTGGACCTGCGGCGCCATAAGAAGTACACGTGTGGCTCAGTGGGGGCTGCGCTCTACGAGGGCCTGGCTGAGGAGCTCAAGCCCGAGGGCCTTG GCGGTGGCAGCGGCCAAGCCCACGAGTGCAAGGACTGCGAGCGGATGTTCCCCAACAAGTACAGCCTGGAGCAGCACATGGTCATCCACACGGAGGAGCG CGAGTACAAATGCGACCAGTGTCCCAAGGCCTTCAACTGGAAGTCCAACCTCATCCGCCACCAGATGTCCCACGACAGCGGCAAACGCTTCGAATGTGAA AACTGCGTGAAGGTGTTCACGGACCCCAGCAACCTTCAGCGGCACATCCGCTCGCAGCACGTGGGCGCTCGGGCCCACGCCTGCCCCGACTGCGGGAAGA CCTTCGCCACGTCCTCCGGCCTCAAGCAGCACAAGCATATCCACAGCACGGTGAAGCCTTTCATATGTGAGGTCTGCCACAAGTCCTACACGCAGTTCTC CAACCTGTGCCGGCACAAGCGGATGCACGCCGACTGCCGCACGCAGATCAAGTGCAAGGACTGTGGCCAGATGTTCAGCACTACCTCCTCCCTCAACAAG CACCGGCGCTTCTGCGAGGGCAAGAACCATTACACGCCGGGCGGCATCTTTGCCCCGGGCCTGCCCTTGACCCCCAGCCCCATGATGGACAAGGCAAAAC CCTCCCCCAGCCTCAATCACGCCAGCCTGGGCTTCAACGAGTACTTTCCCTCCAGGCCGCACCCGGGGAGCCTGCCCTTCTCCACGGCGCCTCCCACGTT CCCCGCACTCACCCCCGGCTTCCCGGGCATCTTCCCTCCATCCTTGTACCCCCGGCCGCCTCTGCTACCTCCCACATCGCTGCTCAAGAGCCCCCTGAAC CACACCCAGGACGCCAAGCTCCCCAGTCCCCTGGGGAACCCAGCCCTGCCCCTGGTCTCCGCCGTCAGCAACAGCAGCCAGGGCACGACGGCAGCTGCGG GGCCCGAGGAGAAGTTCGAGAGCCGCCTGGAGGACTCCTGTGTGGAGAAGCTGAAGACCAGGAGCAGCGACATGTCGGACGGCAGTGACTTTGAGGACGT CAACACCACCACGGGGACCGACCTGGACACGACCACGGGGACGGGCTCGGACCTGGACAGCGACGTGGACAGCGACCCTGACAAGGACAAGGGCAAGGGC AAGTCCGCCGAGGGCCAGCCCAAGTTTGGGGGCGGCTTGGCGCCCCCGGGGGCCCCGAACAGCGTGGCCGAGGTGCCTGTCTTCTATTCCCAGCACTCAT TCTTCCCGCCACCCGACGAGCAGCTGCTGACTGCAACGGGCGCCGCCGGGGACTCCATCAAGGCCATCGCATCCATTGCCGAGAAGTACTTTGGCCCCGG CTTCATGGGGATGCAGGAGAAGAAGCTGGGCTCGCTCCCCTACCACTCGGCGTTCCCCTTCCAGTTCCTGCCCAACTTCCCCCACTCCCTTTACCCCTTC ACGGACCGAGCCCTCGCCCACAACTTGCTGGTCAAGGCCGAGCCAAAGTCACCCCGGGACGCCCTCAAGGTGGGCGGCCCCAGTGCCGAGTGCCCCTTTG ATCTCACCACCAAGCCCAAAGACGTGAAGCCCATCCTGCCCATGCCCAAGGGCCCCTCGGCCCCCGCATCCGGCGAGGAGCAGCCGCTGGACCTGAGCAT CGGCAGCCGGGCCCGTGCCAGCCAAAACGGCGGCGGGCGGGAGCCCCGCAAGAACCACGTCTATGGGGAACGCAAGCTGGGCGCCGGCGAGGGGCTGCCC CAGGTGTGCCCGGCGCGGATGCCCCAGCAGCCCCCGCTCCACTACGCCAAGCCCTCGCCCTTCTTCATGGACCCCATCTACAGGGTAGAAAAGCGGAAGG TCACAGACCCCGTGGGAGCCCTGAAGGAGAAGTACCTGCGGCCGTCCCCGCTGCTCTTCCACCCCCAGATGTCAGCCATAGAGACCATGACAGAGAAGCT GGAGAGCTTTGCAGCCATGAAGGCGGACTCGGGCAGCTCCCTGCAGCCCCTCCCCCACCACCCCTTCAACTTCCGGTCCCCACCCCCAACGCTCTCCGAC CCCATCCTCAGGAAGGGCAAGGAGCGATACACGTGCAGGTACTGTGGGAAGATCTTCCCCAGATCAGCCAATCTCACCAGACACCTGAGGACGCACACTG GGGAGCAGCCGTACAGGTGTAAGTACTGCGACCGCTCCTTCAGCATCTCTTCGAACCTCCAGCGGCACGTCCGGAACATCCACAACAAGGAGAAGCCTTT CAAGTGCCACCTGTGCAACCGCTGCTTCGGGCAGCAGACCAACCTGGACCGGCACCTCAAGAAGCACGAGCACGAGAACGCACCAGTGAGCCAGCACCCC GGGGTCCTCACGAACCACCTGGGGACCAGCGCGTCCTCTCCCACCTCAGAGTCGGACAACCACGCACTTTTAGACGAGAAAGAAGACTCTTATTTCTCGG AAATCAGAAACTTTATTGCCAATAGTGAGATGAACCAAGCATCAACGCGAACAGAGAAACGGGCGGACATGCAGATCGTGGACGGCAGTGCCCAGTGTCC AGGCCTAGCCAGTGAGAAGCAGGAGGACGTGGAGGAGGAGGACGACGATGACCTGGAGGAGGACGATGAGGACAGCCTGGCCGGGAAGTCGCAGGATGAC ACCGTGTCCCCCGCACCCGAGCCCCAGGCCGCCTACGAGGATGAGGAGGATGAGGAGCCAGCCGCCTCCCTGGCCGTGGGCTTTGACCACACCCGAAGGT GTGCTGAGGACCACGAAGGCGGTCTGTTAGCTTTGGAGCCGATGCCGACTTTTGGGAAGGGGCTGGACCTCCGCAGAGCAGCTGAGGAAGCATTTGAAGT TAAAGATGTGCTTAATTCCACCTTAGATTCTGAGGCTTTAAAACATACACTGTGCAGGCAGGCTAAGAACCAGGCATATGCAATGATGCTGTCCCTTTCC GAAGACACTCCTCTCCACACCCCCTCCCAGGGTTCTCTGGACGCTTGGTTGAAGGTCACTGGAGCCACGTCGGAGTCTGGAGCATTTCACCCCATCAACC ACCTCTGACGGGCTGGGCAGCCGGGGGCCGGTGGCCAGAGCGAGGGCACCAGCCACGAAGGACGGAGGCGGGCGGGGCCCCGGAGAACCCTGTCCCTGCG TGTGGCCACTCCTCAGCATCCTCCCCACCCACCATGGTTCATTCCGACTTTTCCAATGGAAACTCAGATCCCAAAAGTCCCTAAAGCAGTCGTAGAGTCT CACCATCTCCAAGGATTGGTCTTGAGAACACTGTTCAGTGACGGCCATGCAGGTGGCCGTCCAAAGACAGCCAACGGAGCTGCCTCGCAGAATCAGCCAG TGGGCAGGTGGACGCTCTGCTGAGACAGAAGCTGGTGGCCACTGCCGGGTGCCCGCGTGGGGTCGCGGAAGGGAATGGATAGACTGGTGTGCTCAAAAGA GAGAGATCACTCAAATGATTTTTATAATGAAATGACAAGAATAACCCTTTTGGTAACCGTATTGACTGCAGAGTCTATTTAAGCATGTGGTTTTAAAAAT AGACAGTATTTTTTAAAAATCAAAAAATGACTTGCAAATTGTTTTTTAAAAGTAATTTTGCATTGCTTTGAAATTTGAGCTCATTTGCAAACCCGAGTCT GCCTGGGAACCCGCACTGTGCCTGGGTGTATTCTTTATACTGTAGATAATGGAGAAATTTTCTATCTCTGTCCCTATTTGTATAAGCCAAGGTGATGCTG GGTGCCCCGAGGCAGAACAAGAGGCGCGGGGCCACACCCGTGAACCATGCAGACGGCCGAAGAAGTCTTAGGCAGGGCGCCCTGGGCTGCAGGCCTGCCC GAGGCTGGGATGGGAAGTGTGCCTGCCCTCGTGTGACATGGAATTGGTGTCAGGACCGCCACGTGGCCTTCAGAGGAATCCACAGGTCCCCACCCAAGAT CCCTCAATTATATGGGGAAGTCGAGGGCCTGTGGCTTGGATCCGCCATGCAGAGATGTGGCCGGGCACCCATCTTCCTTCCCTCCTCTGTCCCTGCCTCG GCCACCCCACGCGGGAACCCAGCGCCGTCCTCTGAAGGCAGGGCCTTGGCCACGTCCTGGGTCTCCCACCTCCCACCTGACCCCAGCGGCTCCGGTGTCC TCCACGTGGCTGCCCTGGGGAGCAATCCCAGCGGATCGCTCCGGGCCACCAAGCCGCACCTGTGCCTGAGACTCCGGATGGACGACACAGTCGTCACGTC GCTCTTCCTGCGGGTTCTTGGCGAGACACAGCTTGAGAACAGAAGGGCGTCGGGGGAACCTGCCGCAAGGAGCAGAGACAGCACAGCCCCCCGGGCCCAG CCGCCTCCCTCTCTTGGGACGCAACTTCTTCCCCACTCGGATGGGCTTTAAATTATTCCCATAGGGGCCAATTTCAAATAATAATTTTTTTCCCTGATGG AATTTACCTTAATCTGTATATAACTTGTAATTTTTTCTAATTCATTTCTTTTCTTATTTTATTTCCTCCTTAACAGTATTTTTGGCATTAGACATTCTTA TTGTGAAGAAATAATGTTAATATAAGTATCTGGTGAAGGACCAAAACCGTGTGATAAGGTTGTGTGTCGTGTGGGAGTGGGGCGATTTTTTATGTGCCAA ATACCCCCGTCCCCCCCATGAATCCTGCTGTCCCTGCTGCCGTTTACCAGACAATCATATGTTTTTGTTAAATTTGCGTTTCAGTTACATTTGCATTTAA GACAAGTGTTCTATTTATTTCTTGTATTGTTTGGAAGAAAAAATGATGATAGAGTCCCAAAAAGAAGAGAAAAAAAATGCCCAAGTTGCCCTTTAAAAAA AAAGAGCGTAAATACAAACAGGAGTGGTGCAAGCCGCCTTGGTGTGGGTTTGTGTCACGTGTGGACATCTCCTCAGGCTTTGTGTCACGCGTGGACATCT CCTCAGGCTGTCCCCAGCGGTGACGGGAGGTGTCCTGGCTGCTCCAGGACAAAAGACAATCGTCTCTGTGGGTGCCGGGTGGTCCAGGCTTGCACTGAAG ACGTGCCACGGGGAGGCTCCTGCAGGAGGCTCAACCCGACGGATCACAGTGAAAGGGATTCCTCCCACGCCAGATCTGCACAACGAGGCAAGACAGGACC CACCTGTGCGTGCGCTGGGGCCATGGGGTGGCCCCGCCGGGGCAGCGGGGGAGCTGCCTGCAGAAGAGCCAGCTGGCGTGTCGGGAAGGATCCAGGATCT GCAAACACAACTGCTCAGGCCTTCTCACGCGTTTCCACAACATCCCCTGGGTCAGACCCACCAGGTACCCCGTAGGAATTTCCAGTTTCCCTTGATCTAG ATGGGATTCTTATAAAAATTCAACCTCAGACATAAACACCCCATTTCTGTAAACCCAAATTATATGGTTTCTTCTGCGAAAGAGTAAGGTGTGTGCTTTT TTTTTTTTGCAATATGACCCCGTCTCTCTGAAGTGGGACATTCGGACGGATGGAGCCCTCAGCGTGTCTTTTCAGCAGGAGCAGAACCGATGAGAGCCGC CCTTACCGTTGGTCTCCGGATCCCCCAGTCCCATCCCGCCGTTTTCGGCTGTCTTCCTAACCGTCCTGTCTTCTCTTGGCGCTCTTTCCTTCCACCTTTC CCAAGAGTCCTGGTTGCACGTTTTAAGTCATATATTTTCGTCCCCCTGAAAATGATGGCAAGCCCAGTTTCTCCTGAGCATTCAGACCCCCAGGCCCCAG CACTTGGCGTTTTCAGGAGGCCCTGTTCTTAGAGCCCCTGACAAAGGCAGCACTTATTTCCTGGGCTGGTGCGCCCCAAAACACGGCCCCGACACTTAGT GTGGCCCCAGGCCCCAGCGAGCCTCGCCCTCCCAGTTTTGCTCTGCCCAGCAGTGTTGGTGCCCAGAGATGACAAGGGCCAGGGAGCCTGGCCCGGGTGT GAGAATTCAGAGATTCTGGCCTCCAGCTGTCACCACACCGTAACGGGGCCATGTAACTGTGCAGCATGGACAGGGATGCGACGGGGCAGCTGGCTGTGTC CATGGCCAGGTGGCCAGGGTCAGGGCTGCAAGCCAGGGGTCCAGGGCCCTTCCGTTCAGCCCAAATGCTGCCCCAATGCTAACTCCTTGGATTGTCAACC CCCATCCCCCAAATGGAAATTCCGAAGGAGGCCTCCTCGCACCTGCCCTCCGCTGCTCCTCAGACCCCAGCCCCCAGCGAGCCGACGTCCCCACCCGTTC CTGCTCTCATCCCCAGGTTGGGCACGTGGGGTTCCTCCTCTGTGGGCCTGGCAGACCCTTCATGAGTGGGACCCAAGATATCACTGACTTCAACCCAGAG GATCGAGCCCCTGCACCCTGCCTGGGGCCCTGGGGTGTGGAGCAGTGGCTGGGGTGGGCGTGGTGTGGCCTGAGAGACTGCCCAGCTGGAGAGGCCTTCC TTTACAAGGCCACGCGTGCAGCTGTCCCATCCAGACCCCGACTGGCCAAGACCTCCACGTCCCCAGAGTCCAGCCCTGGAAATTCCAAGGGCCCTGGCGT CCTCTGCCTTCCCCGCTTCCCCATGAGCGTCTGCAAAACACTTGCCTGAATACATATCACGTATTTTAGACTCGAAGCCTCAAAGCACTGGATTGTGGTC CCCTGCCCCCTCTGTCCCGTCCCCCTGCCCAAGTGACTGAAACCTACTGAGCTATATTCACTGTGCTGTCCTAGGGGGAGGGAGAGCAGAGCTCGCCCCT GCACTGCAGCCTTGTGGGGGAGGGCAAGGCTCTCCTCCCAGCCAGGGACGCCAGGACATAGCTGCTCCTGGTCAGTGGAGGTCAGCCGGGTATCAAAAGC CATGAAACTGTGTCTCTGTAGCAATGAGTGATACTGTGACAAAACCATCCTTGCATTCTTCCTAGAAGAGTTCCTCTGCTCCTTCCATTCCATTTTTGTG TTTGTTTTGTTCTTTTCTGTCACTGATCCGTATTACCACTTTTGGAAAAAAATAAATAAATAAATAAATAAAAGGCAGCTTGAGTTTCCAAACGTGTGAT TCACTTGTGAACAAAAGTCATTCTAACAATTGCCTTCAGCGTCACGTGCATTGCCACTGCGCTTTCGGCACGAGGGATGCTGAGCCCTGGTGTCAGAGTC GTAATTTAAAGCGTGTGTGTATATGGACTTTGTCCCTTAAGGTCGATATAAAGAATCCTCGCAGAATCACAGACCTGTGCCGCCCGCCACCTTCTGCCAT TGTTACATTACAGATTTGGTTTAGTTTTGTTTTGTTTTGTTTTTTCTTTTAGAACTGTATAGTATTGAAAAAGAAATCAAATGTAAATGTCTGGTTTTCA TATAATGTTTAAAAAGACCATTGAGAAGGAGGCTGGCGCTCGCCCCATGTCCCCCTTGATTGTAAATTGCTTCTGTTCTGTTTATAAGTAAACTGTGCAT GACTCCTGCTTAGCGGTCATTATCGTGTCTGTTGGTGAAATTTTTATTAAAAGGAAAATTCTGTAGATGCACTTATTGAATATGTGATTAGGATCTACGT CTGAGACTAGGAGTCCTGAACTGCTGACGCGAAAGAGGCGCAGTTCCCAATTAATACGGAAATCGCTGTGGGAGAAGAATGAAATAAGACGTGAAGTGTA GGAAATCATGAAAAGAACAATTTTGCAAATTGCATTCTGATGCTTGTGATGAACACAAATGTACTTGTGTAGAGACATTTCCTTAAGAGAAAGCCTAGGA GAAGCCGATTTGGAGGTTAATGCTGTAGAATAGGACTGTATACCAAATGTAATCTTTCCAATGCTCCAATGAATTTATACATGAGATTGATATGCAATAA ATCTGTGTGCTTTTCTAA

refseq_PRDM16.F1 (forward primer)
refseq_PRDM16.R1 (reverse primer)
Alternative acceptor

Frame 0

DNAGEMKIVCGCFWTQGGGERFREPTPCDPRRG RGS*PKVTVTL*IICMSPTGTCWPATARRTRPRT VPCRPSPWGHRPPSPPARTSPPRRARRTRPLST FLKTFRSQQTSSSESPPSQGLAWGSGPRGRWKP GRGWAPAWWCPGRRQRRQTSDGSKY*RTWKCRPR KAASQRSPKTWAVRSSAWMQIRRGLAAGSSTSV WRAPAMTRTSPCVRSVSRFTIKSLRTLSQVRSC WCT*RKASTPWAQCRPAWTRSPRSAVTSVTNSSS PSWTCGAIRSTRVAQWGLRSTRAWLRSSSPRAL AVAAAKPTSARTASGCSPTSTAWSSTWSSTRRS ASTNATSVPRPSTGSPTSSATRCPTTAANASNVK TA*RCSRTPATFSGTSARSTWALGPTPAPTAGR PSPRPPASSSTSISTAR*SLSYVRSATSPTRSS PTCAGTSGCTPTAARRSSARTVARCSALPPPSTS TGASARARTITRRAASLPRACP*PPAP*WTRQN PPPASITPAWASTSTFPPGRTRGACPSPRRLPR SPHSPPASRASSLHPCTPGRLCYLPHRCSRAP*T TPRTPSSPVPWGTQPCPWSPPSATAARARRQLR GPRRSSRAAWRTPVWRS*RPGAATCRTAVTLRT STPPRGPTWTRPRGRARTWTATWTATLTRTRARA SPPRASPSLGAAWRPRGPRTAWPRCLSSIPSTH SSRHPTSSC*LQRAPPGTPSRPSHPLPRSTLAP ASWGCRRRSWARSPTTRRSPSSSCPTSPTPFTPS RTEPSPTTCWSRPSQSHPGTPSRWAAPVPSAPL ISPPSPKT*SPSCPCPRAPRPPHPARSSRWT*A SAAGPVPAKTAAGGSPARTTSMGNASWAPARGCP RCARRGCPSSPRSTTPSPRPSSWTPSTG*KSGR SQTPWEP*RRSTCGRPRCSSTPRCQP*RP*QRS WRALQP*RRTRAAPCSPSPTTPSTSGPHPQRSPT PSSGRARSDTRAGTVGRSSPDQPISPDT*GRTL GSSRTGVSTATAPSASLRTSSGTSGTSTTRRSL SSATCATAASGSRPTWTGTSRSTSTRTHQ*ASTP GSSRTTWGPARPLPPQSRTTTHF*TRKKTLISR KSETLLPIVR*TKHQREQRNGRTCRSWTAVPSV QA*PVRSRRTWRRRTTMTWRRTMRTAWPGSRRMT PCPPHPSPRPPTRMRRMRSQPPPWPWALTTPEG VLRTTKAVC*LWSRCRLLGRGWTSAEQLRKHLK LKMCLIPP*ILRL*NIHCAGRLRTRHMQ*CCPFP KTLLSTPPPRVLWTLG*RSLEPRRSLEHFTPST TSDGLGSRGPVARARAPATKDGGGRGPGEPCPC VWPLLSILPTHHGSFRLFQWKLRSQKSLKQS*SL TISKDWS*EHCSVTAMQVAVQRQPTELPRRISQ WAGGRSAETEAGGHCRVPAWGRGREWIDWCAQK REITQMIFIMK*QE*PFW*PY*LQSLFKHVVLKI DSIF*KSKNDLQIVF*K*FCIALKFELICKPES AWEPALCLGVFFIL*IMEKFSISVPICISQGDA GCPEAEQEARGHTREPCRRPKKS*AGRPGLQACP RLGWEVCLPSCDMELVSGPPRGLQRNPQVPTQD PSIIWGSRGPVAWIRHAEMWPGTHLPSLLCPCL GHPTREPSAVL*RQGLGHVLGLPPPT*PQRLRCP PRGCPGEQSQRIAPGHQAAPVPETPDGRHSRHV ALPAGSWRDTA*EQKGVGGTCRKEQRQHSPPGP AASLSWDATSSPLGWALNYSHRGQFQIIIFFPDG IYLNLYITCNFF*FISFLILFPP*QYFWH*TFL L*RNNVNISIW*RTKTV**GCVSCGSGAIFYVP NTPVPPMNPAVPAAVYQTIICFC*ICVSVTFAFK TSVLFISCIVWKKK***SPKKKRKKMPKLPFKK KERKYKQEWCKPPWCGFVSRVDISSGFVSRVDI SSGCPQR*REVSWLLQDKRQSSLWVPGGPGLH*R RATGRLLQEAQPDGSQ*KGFLPRQICTTRQDRT HLCVRWGHGVAPPGQRGSCLQKSQLACREGSRI CKHNCSGLLTRFHNIPWVRPTRYPVGISSFP*SR WDSYKNSTSDINTPFL*TQIIWFLLRKSKVCAF FFLQYDPVSLKWDIRTDGALSVSFQQEQNR*EP PLPLVSGSPSPIPPFSAVFLTVLSSLGALSFHLS QESWLHVLSHIFSSP*K*WQAQFLLSIQTPRPQ HLAFSGGPVLRAPDKGSTYFLGWCAPKHGPDT* CGPRPQRASPSQFCSAQQCWCPEMTRAREPGPGV RIQRFWPPAVTTP*RGHVTVQHGQGCDGAAGCV HGQVARVRAASQGSRALPFSPNAAPMLTPWIVN PHPPNGNSEGGLLAPALRCSSDPSPQRADVPTRS CSHPQVGHVGFLLCGPGRPFMSGTQDITDFNPE DRAPAPCLGPWGVEQWLGWAWCGLRDCPAGEAF LYKATRAAVPSRPRLAKTSTSPESSPGNSKGPGV LCLPRFPMSVCKTLA*IHITYFRLEASKHWIVV PCPLCPVPLPK*LKPTELYSLCCPRGRESRARP CTAALWGRARLSSQPGTPGHSCSWSVEVSRVSKA MKLCLCSNE*YCDKTILAFFLEEFLCSFHSIFV FVLFFSVTDPYYHFWKKINK*INKRQLEFPNV* FTCEQKSF*QLPSASRALPLRFRHEGC*ALVSES *FKACVYMDFVP*GRYKESSQNHRPVPPATFCH CYITDLV*FCFVLFFLLELYSIEKEIKCKCLVF I*CLKRPLRRRLALAPCPP*L*IASVLFISKLCM TPA*RSLSCLLVKFLLKGKFCRCTY*ICD*DLR LRLGVLNC*RERGAVPN*YGNRCGRRMK*DVKC RKS*KEQFCKLHSDACDEHKCTCVETFP*EKA*E KPIWRLML*NRTVYQM*SFQCSNEFIHEIDMQ* ICVLF*

Frame 1

TMLGR*R*CVAASGLKEEERDSASRHHAIQGEG EEASQK*R*RCK*YV*AQPGPAGQPQRGGRGRG QCHVAHPRGATVPLPHQRGLHPQGGLAVRGPCLH S*RHSDPSRLRAPRVLHPRGWPGGLGQEEDGSR GEAGPLRGGAPGGGKGDRLRMGANTDGRGSVAP GRLHHKDLRRPGQ*EVLRGCKSGGGWQLAQVHPC GVLLR*PEPHHVSDQ*ADLL*SH*GH*AR*GAA GAREGRRLPPGHSAARPGRGAHVPL*RV*RTLP VQAGPAAP*EVHVWLSGGCALRGPG*GAQARGPW RWQRPSPRVQGLRADVPQQVQPGAAHGHPHGGA RVQMRPVSQGLQLEVQPHPPPDVPRQRQTLRM* KLREGVHGPQQPSAAHPLAARGRSGPRLPRLRED LRHVLRPQAAQAYPQHGEAFHM*GLPQVLHAVL QPVPAQADARRLPHADQVQGLWPDVQHYLLPQQ APALLRGQEPLHAGRHLCPGPALDPQPHDGQGKT LPQPQSRQPGLQRVLSLQAAPGEPALLHGASHV PRTHPRLPGHLPSILVPPAASATSHIAAQEPPE PHPGRQAPQSPGEPSPAPGLRRQQQQPGHDGSCG ARGEVREPPGGLLCGEAEDQEQRHVGRQ*L*GR QHHHGDRPGHDHGDGLGPGQRRGQRP*QGQGQG QVRRGPAQVWGRLGAPGGPEQRGRGACLLFPALI LPATRRAAADCNGRRRGLHQGHRIHCREVLWPR LHGDAGEEAGLAPLPLGVPLPVPAQLPPLPLPL HGPSPRPQLAGQGRAKVTPGRPQGGRPQCRVPL* SHHQAQRREAHPAHAQGPLGPRIRRGAAAGPEH RQPGPCQPKRRRAGAPQEPRLWGTQAGRRRGAA PGVPGADAPAAPAPLRQALALLHGPHLQGRKAEG HRPRGSPEGEVPAAVPAALPPPDVSHRDHDREA GELCSHEGGLGQLPAAPPPPPLQLPVPTPNALR PHPQEGQGAIHVQVLWEDLPQISQSHQTPEDAHW GAAVQV*VLRPLLQHLFEPPAARPEHPQQGEAF QVPPVQPLLRAADQPGPAPQEARARERTSEPAP RGPHEPPGDQRVLSHLRVGQPRTFRRERRLLFLG NQKLYCQ**DEPSINANRETGGHADRGRQCPVS RPSQ*EAGGRGGGGRR*PGGGR*GQPGREVAG* HRVPRTRAPGRLRG*GG*GASRLPGRGL*PHPKV C*GPRRRSVSFGADADFWEGAGPPQSS*GSI*S *RCA*FHLRF*GFKTYTVQAG*EPGICNDAVPF RRHSSPHPLPGFSGRLVEGHWSHVGVWSISPHQP PLTGWAAGGRWPERGHQPRRTEAGGAPENPVPA CGHSSASSPPTMVHSDFSNGNSDPKSP*SSRRV SPSPRIGLENTVQ*RPCRWPSKDSQRSCLAESAS GQVDALLRQKLVATAGCPRGVAEGNG*TGVLKR ERSLK*FL**NDKNNPFGNRIDCRVYLSMWF*K *TVFFKNQKMTCKLFFKSNFALL*NLSSFANPSL PGNPHCAWVYSLYCR*WRNFLSLSLFV*AKVML GAPRQNKRRGATPVNHADGRRSLRQGALGCRPA RGWDGKCACPRVTWNWCQDRHVAFRGIHRSPPKI PQLYGEVEGLWLGSAMQRCGRAPIFLPSSVPAS ATPRGNPAPSSEGRALATSWVSHLPPDPSGSGV LHVAALGSNPSGSLRATKPHLCLRLRMDDTVVTS LFLRVLGETQLENRRASGEPAARSRDSTAPRAQ PPPSLGTQLLPHSDGL*IIPIGANFK**FFSLM EFTLICI*LVIFSNSFLFLFYFLLNSIFGIRHSY CEEIMLI*VSGEGPKPCDKVVCRVGVGRFFMCQ IPPSPP*ILLSLLPFTRQSYVFVKFAFQLHLHL RQVFYLFLVLFGRKNDDRVPKRREKKCPSCPLKK KSVNTNRSGASRLGVGLCHVWTSPQALCHAWTS PQAVPSGDGRCPGCSRTKDNRLCGCRVVQACTE DVPRGGSCRRLNPTDHSERDSSHARSAQRGKTGP TCACAGAMGWPRRGSGGAACRRASWRVGKDPGS ANTTAQAFSRVSTTSPGSDPPGTP*EFPVSLDL DGILIKIQPQT*TPHFCKPKLYGFFCERVRCVLF FFCNMTPSL*SGTFGRMEPSACLFSRSRTDESR PYRWSPDPPVPSRRFRLSS*PSCLLLALFPSTF PKSPGCTF*VIYFRPPENDGKPSFS*AFRPPGPS TWRFQEALFLEPLTKAALISWAGAPQNTAPTLS VAPGPSEPRPPSFALPSSVGAQR*QGPGSLARV *EFRDSGLQLSPHRNGAM*LCSMDRDATGQLAVS MARWPGSGLQARGPGPFRSAQMLPQC*LLGLST PIPQMEIPKEASSHLPSAAPQTPAPSEPTSPPV PALIPRLGTWGSSSVGLADPS*VGPKISLTSTQR IEPLHPAWGPGVWSSGWGGRGVA*ETAQLERPS FTRPRVQLSHPDPDWPRPPRPQSPALEIPRALA SSAFPASP*ASAKHLPEYISRILDSKPQSTGLWS PAPSVPSPCPSD*NLLSYIHCAVLGGGRAELAP ALQPCGGGQGSPPSQGRQDIAAPGQWRSAGYQK P*NCVSVAMSDTVTKPSLHSS*KSSSAPSIPFLC LFCSFLSLIRITTFGKK*INK*IKGSLSFQTCD SLVNKSHSNNCLQRHVHCHCAFGTRDAEPWCQS RNLKRVCIWTLSLKVDIKNPRRITDLCRPPPSAI VTLQIWFSFVLFCFFF*NCIVLKKKSNVNVWFS YNV*KDH*EGGWRSPHVPLDCKLLLFCL*VNCA *LLLSGHYRVCW*NFY*KENSVDALIEYVIRIYV *D*ES*TADAKEAQFPINTEIAVGEE*NKT*SV GNHEKNNFANCILMLVMNTNVLV*RHFLKRKPR RSRFGG*CCRIGLYTKCNLSNAPMNLYMRLICNK SVCFS

Frame 2

QCWGDEDSVWLLLDSRRRREIPRADTMRSKARA RKLAKSDGDVVNNMYEPNRDLLASHSAEDEAED SAMSPIPVGPPSPFPTSEDFTPKEGSPYEAPVY IPEDIPIPADFELRESSIPGAGLGVWAKRKMEAG ERLGPCVVVPRAAAKETDFGWEQILTDVEVSPQ EGCITKISEDLGSEKFCVDANQAGAGSWLKYIR VACSCDDQNLTMCQISEQIYYKVIKDIEPGEELL VHVKEGVYPLGTVPPGLDEEPTFRCDECDELFQ SKLDLRRHKKYTCGSVGAALYEGLAEELKPEGL GGGSGQAHECKDCERMFPNKYSLEQHMVIHTEER EYKCDQCPKAFNWKSNLIRHQMSHDSGKRFECE NCVKVFTDPSNLQRHIRSQHVGARAHACPDCGK TFATSSGLKQHKHIHSTVKPFICEVCHKSYTQFS NLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNK HRRFCEGKNHYTPGGIFAPGLPLTPSPMMDKAK PSPSLNHASLGFNEYFPSRPHPGSLPFSTAPPTF PALTPGFPGIFPPSLYPRPPLLPPTSLLKSPLN HTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAA GPEEKFESRLEDSCVEKLKTRSSDMSDGSDFEDV NTTTGTDLDTTTGTGSDLDSDVDSDPDKDKGKG KSAEGQPKFGGGLAPPGAPNSVAEVPVFYSQHS FFPPPDEQLLTATGAAGDSIKAIASIAEKYFGPG FMGMQEKKLGSLPYHSAFPFQFLPNFPHSLYPF TDRALAHNLLVKAEPKSPRDALKVGGPSAECPF DLTTKPKDVKPILPMPKGPSAPASGEEQPLDLSI GSRARASQNGGGREPRKNHVYGERKLGAGEGLP QVCPARMPQQPPLHYAKPSPFFMDPIYRVEKRK VTDPVGALKEKYLRPSPLLFHPQMSAIETMTEKL ESFAAMKADSGSSLQPLPHHPFNFRSPPPTLSD PILRKGKERYTCRYCGKIFPRSANLTRHLRTHT GEQPYRCKYCDRSFSISSNLQRHVRNIHNKEKPF KCHLCNRCFGQQTNLDRHLKKHEHENAPVSQHP GVLTNHLGTSASSPTSESDNHALLDEKEDSYFS EIRNFIANSEMNQASTRTEKRADMQIVDGSAQCP GLASEKQEDVEEEDDDDLEEDDEDSLAGKSQDD TVSPAPEPQAAYEDEEDEEPAASLAVGFDHTRR CAEDHEGGLLALEPMPTFGKGLDLRRAAEEAFEV KDVLNSTLDSEALKHTLCRQAKNQAYAMMLSLS EDTPLHTPSQGSLDAWLKVTGATSESGAFHPIN HL*RAGQPGAGGQSEGTSHEGRRRAGPRRTLSLR VATPQHPPHPPWFIPTFPMETQIPKVPKAVVES HHLQGLVLRTLFSDGHAGGRPKTANGAASQNQP VGRWTLC*DRSWWPLPGARVGSRKGMDRLVCSKE RDHSNDFYNEMTRITLLVTVLTAESI*ACGFKN RQYFLKIKK*LANCFLKVILHCFEI*AHLQTRV CLGTRTVPGCILYTVDNGEIFYLCPYLYKPR*CW VPRGRTRGAGPHP*TMQTAEEVLGRAPWAAGLP EAGMGSVPALV*HGIGVRTATWPSEESTGPHPR SLNYMGKSRACGLDPPCRDVAGHPSSFPPLSLPR PPHAGTQRRPLKAGPWPRPGSPTSHLTPAAPVS STWLPWGAIPADRSGPPSRTCA*DSGWTTQSSR RSSCGFLARHSLRTEGRRGNLPQGAETAQPPGPS RLPLLGRNFFPTRMGFKLFP*GPISNNNFFP*W NLP*SVYNL*FFLIHFFSYFISSLTVFLALDIL IVKK*C*YKYLVKDQNRVIRLCVVWEWGDFLCAK YPRPPHESCCPCCRLPDNHMFLLNLRFSYICI* DKCSIYFLYCLEEKMMIESQKEEKKNAQVAL*K KRA*IQTGVVQAALVWVCVTCGHLLRLCVTRGHL LRLSPAVTGGVLAAPGQKTIVSVGAGWSRLALK TCHGEAPAGGSTRRITVKGIPPTPDLHNEARQD PPVRALGPWGGPAGAAGELPAEEPAGVSGRIQDL QTQLLRPSHAFPQHPLGQTHQVPRRNFQFPLI* MGFL*KFNLRHKHPISVNPNYMVSSAKE*GVCF FFFAI*PRLSEVGHSDGWSPQRVFSAGAEPMRAA LTVGLRIPQSHPAVFGCLPNRPVFSWRSFLPPF PRVLVARFKSYIFVPLKMMASPVSPEHSDPQAP ALGVFRRPCS*SP*QRQHLFPGLVRPKTRPRHLV WPQAPASLALPVLLCPAVLVPRDDKGQGAWPGC ENSEILASSCHHTVTGPCNCAAWTGMRRGSWLC PWPGGQGQGCKPGVQGPSVQPKCCPNANSLDCQP PSPKWKFRRRPPRTCPPLLLRPQPPASRRPHPF LLSSPGWARGVPPLWAWQTLHEWDPRYH*LQPR GSSPCTLPGALGCGAVAGVGVVWPERLPSWRGLP LQGHACSCPIQTPTGQDLHVPRVQPWKFQGPWR PLPSPLPHERLQNTCLNTYHVF*TRSLKALDCG PLPPLSRPPAQVTETY*AIFTVLS*GEGEQSSPL HCSLVGEGKALLPARDART*LLLVSGGQPGIKS HETVSL*Q*VIL*QNHPCILPRRVPLLLPFHFC VCFVLFCH*SVLPLLEKNK*INK*KAA*VSKRVI HL*TKVILTIAFSVTCIATALSARGMLSPGVRV VI*SVCVYGLCPLRSI*RILAESQTCAARHLLP LLHYRFGLVLFCFVFSFRTV*Y*KRNQM*MSGFH IMFKKTIEKEAGARPMSPLIVNCFCSVYK*TVH DSCLAVIIVSVGEIFIKRKIL*MHLLNM*LGST SETRSPELLTRKRRSSQLIRKSLWEKNEIRREV* EIMKRTILQIAF*CL**TQMYLCRDISLRESLG EADLEVNAVE*DCIPNVIFPMLQ*IYT*D*YAI NLCAFL