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Sequences

Sequence NM_014456

CGACCACCCGGCCTCGGCCAATAAGCGCCGCCCTCTCGCCCCCGTGTTACTGGGTAGAAGAAAACAAAAACAAACAGAGCGAGAAGGGCCAGAGACTCTC
CGAGGCGGCGGCAGAGACAGAAGAGCGGGGTCGGGGCCGGCTGACCAGGAACCTGGGCGAGCAGCGGCGGGGGCCCGAGGGATTCTGAAGGAAGATTTCC
ATTAGGTAATTTGTTTAATCAGTGCAAGCGAAATTAAGGGAAAATGGATGTAGAAAATGAGCAGATACTGAATGTAAACCCTGCAGATCCTGATAACTTA
AGTGACTCTCTCTTTTCCGGTGATGAAGAAAATGCTGGGACTGAGGAAATAAAGAATGAAATAAATGGAAATTGGATTTCAGCATCCTCCATTAACGAAG
CTAGAATTAATGCCAAGGCAAAAAGGCGACTAAGGAAAAACTCATCCCGGGACTCTGGCAGAGGCGATTCGGTCAGCGACAGTGGGAGTGACGCCCTTAG
AAGTGGAT
TAACTGTGCCAACCAGTCCAAAGGGAAGGTTGCTGGATAGGCGATCCAGATCTGGGAAAGGAAGGGGACTACCAAAGAAAGGTGGTGCAGGA
GGCAAAGGTGTCTGGGGTACACCTGGACAGGTGTATGATGTGGAGGAGGTGGATGTGAAAGATCCTAACTATGATGATGACCAGGAGAACTGTGTTTATG
AAACTGTAGTTTTGCCTTTGGATGAAAGGGCATTTGAGAAGACTTTAACACCAATCATACAGGAATATTTTGAGCATGGAGATACTAATGAAGTTGCGGA
AATGTTAAGAGATTTAAATCTTGGTGAAATGAAAAGTGGAGTACCAGTGTTGGCAGTATCCTTAGCATTGGAGGGGAAGGCTAGTCATAGAGAGATGACA
TCTAAGCTTCTTTCTGACCTTTGTGGGACAGTAATGAGCACAACTGATGTGGAAAAATCATTTGATAAATTGTTGAAAGATCTACCTGAATTAGCACTGG
ATACTCCTAGAGCACCACAGTTGGTGGGCCAGTTTATTGCTAGAGCTGTTGGAGATGGAATTTTATGTAATACCTATATTGATAGTTACAAAGGAACTGT
AGATTGTGTGCAGGCTAGAGCTGCTCTGGATAAGGCTACCGTGCTTCTGAGTATGTCTAAAGGTGGAAAGCGTAAAGATAGTGTGTGGGGCTCTGGAGGT
GGGCAGCAATCTGTCAATCACCTTGTTAAAGAGATTGATATGCTGCTGAAAGAATATTTACTCTCTGGAGACATATCTGAAGCTGAACATTGCCTTAAGG
AACTGGAAGTACCTCATTTTCACCATGAGCTTGTATATGAAGCTATTATAATGGTTTTAGAGTCAACTGGAGAAAGTACATTTAAGATGATTTTGGATTT
ATTAAAGTCCCTTTGGAAGTCTTCTACCATTACTGTAGACCAAATGAAAAGAGGTTATGAGAGAATTTACAATGAAATTCCGGACATTAATCTGGATGTC
CCACATTCATACTCTGTGCTGGAGCGGTTTGTAGAAGAATGTTTTCAGGCTGGAATAATTTCCAAACAACTCAGAGATCTTTGTCCTTCAAGGGGCAGAA
AGCGTTTTGTAAGCGAAGGAGATGGAGGTCGTCTTAAACCAGAGAGCTACTGAATATAAGAACTCTTGCAGTCTTAGATGTTATAAAAATATATATCTGA
ATTGTAAGAGTTGTTAGCACAAGTTTTTTTTTTTTTTTTTTTTAAGCACTTGTTTTGGGTACAAGGCATTTCTGACATTTTATAAACCTACATTTAAGGG
GAATTTTTAAAGGAAATGTTTTTTCTTTTTTTTTTGTTTTTCGAGGGGGCAAGGAGGGACAGAAAAGTAACCTCTTCTTAAGTGGAATATTCTAATAAGC
TACCTTTTGTAAGTGCCATGTTTATTATCTAATCATTCCAAGTTTTGCATTGATGTCTGACTGCCACTCCTTTCTTTCAAGGACAGTGTTTTTTGTAGTA
AAATCACTGGTTTATACAAAGCTTTATTTAGGGGGTAAAGTTAAGCTGCTAAAACCCCATGTTGGCTGCTGCTGTTGAGATACTGTGCTTTGGGAGTAAA
AAAAGAAAGTTATTTCTTTGTCTTAAAGAATTTTTAAAAAATTAGTCATGAGACTTATTCATCTTTCCAGGGAACATACTGATTGGTCTTAAAAGACTAG
ACAGTTAAGTAAAAGGTGGCTGGAACATCTATTTTTCTACAAAACTGGAAAAATGAACCTGGTTCTAGAAGAATGTACACCAAAATAAAACATGTGAAGC
AGTATTGATTCTTTATTGGGAGTACATTTTTTTAGGTCTCTTAAACTTTAATTTCACACAGTAAATTTTGAATCTCATAAGGAAGCATATTTGAACCTAG
TCAATTTAATCTTAGTGTTCCCTTGAAAACTTTTTTTCCCTACAAAATTTTAAGTGAAAAATACAATAGTAAATTAAGATTACACTGGGGAAAAAAATGC
AGGTATCACTTTACTCCATTGTTATCTGACCTAGAGCTTAATTAAGTTTTAGAAATATGTAATACCTTCCATCATTCCATCATCCTTAAATTCTGTTACC
AAATAATGGCTAATGTTACAAAAAGTTATACTCCAGAGACCCAAAGCTTGACATTTACCTAATGTATGAGAAAATATTACCAATTAACAATAAAGAATGA
TCATATTTTTAACCTCTTTTACATAGCCTAATAACTCAGCAAGGCCTCAACGTCTGTGCTAATTTAAACTGCCAAATATTGACTGCAGCAAACAAGAATT
ATATTCAGAATTTATGAGGGTACTGTTAGGAGTATACTGCTTACAGGTTTAGATATAGTCTGTTAGAATTAAAACCAAGTTTAGTGTTCATATTTACCTC
ATGGGCTTTATCAAGCCCATATTACCTCAGCTTATATATAGTTACCATTTTTAGGTTTTTAATTGTTTGACACTTGGATGATAAATGCAGTCATTTTATT
CTCAAGTGCTTAAAATTAATGTAATTAAAAGCTTAGCTGACTACAGAATAGGTGAGGGTTTCTTAAAAATGAGATTTAAGGGCTGGGCACGGTGGCTCAT
GCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTTGGGAGTTCATGACCAGCTTGACCAACATGAAGAAACCCTGTCTCTATT
AAAAATACAAAAGTAGCCAGGCATGGTGGCGCATGCGTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTT
GCAGTGAGTCGAGATGGTGCCATTGCTCTCGTTTGGGCAACAAGAGTGAAACTCTTGTCTCAAAAAAAAAAAAAAATGAGGTTTAAGACAGTTTTGTCAT
TACTGGTGGGATCTGGTCACACAAGATAGCATTAAACGTGACATGGCACATAAAATTGGTTAAAAAATTTTGTTTTTTAATTACGTAATGTAAAAGCCCA
ACAAACACTTTATGCAAGATTGGAATGTATCTTCAAATTCAGATTTAATAAACATGTAAAGATCCTCTGTA
  • refseq_PDCD4.F1 (forward primer)
  • refseq_PDCD4.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPPGLGQ*APPSRPRVTG*KKTKTNRARRARDS
PRRRQRQKSGVGAG*PGTWASSGGGPRDSEGRFP
LGNLFNQCKRN*GKMDVENEQILNVNPADPDNL
SDSLFSGDEENAGTEEIKNEINGNWISASSINE
ARINAKAKRRLRKNSSRDSGRGDSVSDSGSDALR
SG
LTVPTSPKGRLLDRRSRSGKGRGLPKKGGAG
GKGVWGTPGQVYDVEEVDVKDPNYDDDQENCVY
ETVVLPLDERAFEKTLTPIIQEYFEHGDTNEVAE
MLRDLNLGEMKSGVPVLAVSLALEGKASHREMT
SKLLSDLCGTVMSTTDVEKSFDKLLKDLPELAL
DTPRAPQLVGQFIARAVGDGILCNTYIDSYKGTV
DCVQARAALDKATVLLSMSKGGKRKDSVWGSGG
GQQSVNHLVKEIDMLLKEYLLSGDISEAEHCLK
ELEVPHFHHELVYEAIIMVLESTGESTFKMILDL
LKSLWKSSTITVDQMKRGYERIYNEIPDINLDV
PHSYSVLERFVEECFQAGIISKQLRDLCPSRGR
KRFVSEGDGGRLKPESY*I*ELLQS*ML*KYISE
L*ELLAQVFFFFFFKHLFWVQGISDIL*TYI*G
EFLKEMFFLFFLFFEGARRDRKVTSS*VEYSNK
LPFVSAMFII*SFQVLH*CLTATPFFQGQCFL**
NHWFIQSFI*GVKLSC*NPMLAAAVEILCFGSK
KRKLFLCLKEFLKN*S*DLFIFPGNILIGLKRL
DS*VKGGWNIYFSTKLEK*TWF*KNVHQNKTCEA
VLILYWEYIFLGLLNFNFTQ*ILNLIRKHI*T*
SI*S*CSLENFFSLQNFK*KIQ**IKITLGKKM
QVSLYSIVI*PRA*LSFRNM*YLPSFHHP*ILLP
NNG*CYKKLYSRDPKLDIYLMYEKILPINNKE*
SYF*PLLHSLITQQGLNVCANLNCQILTAANKN
YIQNL*GYC*EYTAYRFRYSLLELKPSLVFIFTS
WALSSPYYLSLYIVTIFRFLIV*HLDDKCSHFI
LKCLKLM*LKA*LTTE*VRVS*K*DLRAGHGGS
CL*SQHFGRPRWADHLRLGVHDQLDQHEETLSLL
KIQK*PGMVAHACNPSYLGG*GRRIA*TWEAEV
AVSRDGAIALVWATRVKLLSQKKKKMRFKTVLS
LLVGSGHTR*H*T*HGT*NWLKNFVF*LRNVKAQ
QTLYARLECIFKFRFNKHVKILC

Frame 1

DHPASANKRRPLAPVLLGRRKQKQTEREGPETL
RGGGRDRRAGSGPADQEPGRAAAGARGILKEDF
H*VICLISASEIKGKWM*KMSRY*M*TLQILIT*
VTLSFPVMKKMLGLRK*RMK*MEIGFQHPPLTK
LELMPRQKGD*GKTHPGTLAEAIRSATVGVTPL
EVD
*LCQPVQREGCWIGDPDLGKEGDYQRKVVQE
AKVSGVHLDRCMMWRRWM*KILTMMMTRRTVFM
KL*FCLWMKGHLRRL*HQSYRNILSMEILMKLR
KC*EI*ILVK*KVEYQCWQYP*HWRGRLVIER*H
LSFFLTFVGQ**AQLMWKNHLINC*KIYLN*HW
ILLEHHSWWASLLLELLEMEFYVIPILIVTKEL
*IVCRLELLWIRLPCF*VCLKVESVKIVCGALEV
GSNLSITLLKRLICC*KNIYSLETYLKLNIALR
NWKYLIFTMSLYMKLL*WF*SQLEKVHLR*FWI
Y*SPFGSLLPLL*TK*KEVMREFTMKFRTLIWMS
HIHTLCWSGL*KNVFRLE*FPNNSEIFVLQGAE
SVL*AKEMEVVLNQRATEYKNSCSLRCYKNIYL
NCKSC*HKFFFFFFLSTCFGYKAFLTFYKPTFKG
NF*RKCFFFFFCFSRGQGGTEK*PLLKWNILIS
YLL*VPCLLSNHSKFCIDV*LPLLSFKDSVFCS
KITGLYKALFRG*S*AAKTPCWLLLLRYCALGVK
KESYFFVLKNF*KISHETYSSFQGTY*LVLKD*
TVK*KVAGTSIFLQNWKNEPGSRRMYTKIKHVK
QY*FFIGSTFF*VS*TLISHSKF*IS*GSIFEPS
QFNLSVPLKTFFPYKILSEKYNSKLRLHWGKKC
RYHFTPLLSDLELN*VLEICNTFHHSIILKFCY
QIMANVTKSYTPETQSLTFT*CMRKYYQLTIKND
HIFNLFYIA**LSKASTSVLI*TAKY*LQQTRI
IFRIYEGTVRSILLTGLDIVC*N*NQV*CSYLP
HGLYQAHITSAYI*LPFLGF*LFDTWMINAVILF
SSA*N*CN*KLS*LQNR*GFLKNEI*GLGTVAH
ACNPSTLGGRGGRIT*GWEFMTSLTNMKKPCLY
*KYKSSQAWWRMRVIPATWEAEAGELLEPGRQRL
Q*VEMVPLLSFGQQE*NSCLKKKKK*GLRQFCH
YWWDLVTQDSIKRDMAHKIG*KILFFNYVM*KP
NKHFMQDWNVSSNSDLINM*RSSV

Frame 2

TTRPRPISAALSPPCYWVEENKNKQSEKGQRLS
EAAAETEERGRGRLTRNLGEQRRGPEGF*RKIS
IR*FV*SVQAKLRENGCRK*ADTECKPCRS**L
K*LSLFR**RKCWD*GNKE*NKWKLDFSILH*RS
*N*CQGKKATKEKLIPGLWQRRFGQRQWE*RP*
KWI
NCANQSKGKVAG*AIQIWERKGTTKERWCR
RQRCLGYTWTGV*CGGGGCERS*L***PGELCL*
NCSFAFG*KGI*EDFNTNHTGIF*AWRY**SCG
NVKRFKSW*NEKWSTSVGSILSIGGEG*S*RDD
I*ASF*PLWDSNEHN*CGKII**IVERST*ISTG
YS*STTVGGPVYC*SCWRWNFM*YLY**LQRNC
RLCAG*SCSG*GYRASEYV*RWKA*R*CVGLWR
WAAICQSPC*RD*YAAERIFTLWRHI*S*TLP*G
TGSTSFSP*ACI*SYYNGFRVNWRKYI*DDFGF
IKVPLEVFYHYCRPNEKRL*ENLQ*NSGH*SGC
PTFILCAGAVCRRMFSGWNNFQTTQRSLSFKGQK
AFCKRRRWRSS*TRELLNIRTLAVLDVIKIYI*
IVRVVSTSFFFFFF*ALVLGTRHF*HFINLHLR
GIFKGNVFSFFFVFRGGKEGQKSNLFLSGIF**A
TFCKCHVYYLIIPSFALMSDCHSFLSRTVFFVV
KSLVYTKLYLGGKVKLLKPHVGCCC*DTVLWE*
KKKVISLS*RIFKKLVMRLIHLSREHTDWS*KTR
QLSKRWLEHLFFYKTGKMNLVLEECTPK*NM*S
SIDSLLGVHFFRSLKL*FHTVNFESHKEAYLNL
VNLILVFP*KLFFPTKF*VKNTIVN*DYTGEKNA
GITLLHCYLT*SLIKF*KYVIPSIIPSSLNSVT
K*WLMLQKVILQRPKA*HLPNV*ENITN*Q*RM
IIFLTSFT*PNNSARPQRLC*FKLPNIDCSKQEL
YSEFMRVLLGVYCLQV*I*SVRIKTKFSVHIYL
MGFIKPILPQLIYSYHF*VFNCLTLG**MQSFY
SQVLKINVIKSLADYRIGEGFLKMRFKGWARWLM
PVIPALWEAEVGGSLEVGSS*PA*PT*RNPVSI
KNTKVARHGGACV*SQLLGRLRQENCLNLGGRG
CSESRWCHCSRLGNKSETLVSKKKKNEV*DSFVI
TGGIWSHKIALNVTWHIKLVKKFCFLIT*CKSP
TNTLCKIGMYLQIQI**TCKDPL

Sequence NM_145341

CGACCACCCGGCCTCGGCCAATAAGCGCCGCCCTCTCGCCCCCGTGTTACTGGGTAGAAGAAAACAAAAACAAACAGAGCGAGAAGGGCCAGAGACTCTC
CGAGGCGGCGGCAGAGACAGAAGAGCGGGGTCGGGGCCGGCTGACCAGGAACCTGGGCGAGCAGCGGCGGGGGCCCGAGGGATTCTGAAGGAAGATTTCC
ATTAGGTAATTTGTTTAATCAGTGCAAGCGAAATTAAGGGAAAATGGATGTAGAAAATGAGCAGATACTGAATGTAAACCCTGCAGGGTATTTTCCCTAA
TTCTCCATGGTGCTTCAATAGCATGTTATTATCATAAAAATGAACAGTTTTGTGGAATAGATGACCAAAT
ATCCTGATAACTTAAGTGACTCTCTCTTTT
CCGGTGATGAAGAAAATGCTGGGACTGAGGAAATAAAGAATGAAATAAATGGAAATTGGATTTCAGCATCCTCCATTAACGAAGCTAGAATTAATGCCAA
GGCAAAAAGGCGACTAAGGAAAAACTCATCCCGGGACTCTGGCAGAGGCGATTCGGTCAGCGACAGTGGGAGTGACGCCCTTAGAAGTGGATTAACTGTG
CCAACCAGTCCAAAGGGAAGGTTGCTGGATAGGCGATCCAGATCTGGGAAAGGAAGGGGACTACCAAAGAAAGGTGGTGCAGGAGGCAAAGGTGTCTGGG
GTACACCTGGACAGGTGTATGATGTGGAGGAGGTGGATGTGAAAGATCCTAACTATGATGATGACCAGGAGAACTGTGTTTATGAAACTGTAGTTTTGCC
TTTGGATGAAAGGGCATTTGAGAAGACTTTAACACCAATCATACAGGAATATTTTGAGCATGGAGATACTAATGAAGTTGCGGAAATGTTAAGAGATTTA
AATCTTGGTGAAATGAAAAGTGGAGTACCAGTGTTGGCAGTATCCTTAGCATTGGAGGGGAAGGCTAGTCATAGAGAGATGACATCTAAGCTTCTTTCTG
ACCTTTGTGGGACAGTAATGAGCACAACTGATGTGGAAAAATCATTTGATAAATTGTTGAAAGATCTACCTGAATTAGCACTGGATACTCCTAGAGCACC
ACAGTTGGTGGGCCAGTTTATTGCTAGAGCTGTTGGAGATGGAATTTTATGTAATACCTATATTGATAGTTACAAAGGAACTGTAGATTGTGTGCAGGCT
AGAGCTGCTCTGGATAAGGCTACCGTGCTTCTGAGTATGTCTAAAGGTGGAAAGCGTAAAGATAGTGTGTGGGGCTCTGGAGGTGGGCAGCAATCTGTCA
ATCACCTTGTTAAAGAGATTGATATGCTGCTGAAAGAATATTTACTCTCTGGAGACATATCTGAAGCTGAACATTGCCTTAAGGAACTGGAAGTACCTCA
TTTTCACCATGAGCTTGTATATGAAGCTATTATAATGGTTTTAGAGTCAACTGGAGAAAGTACATTTAAGATGATTTTGGATTTATTAAAGTCCCTTTGG
AAGTCTTCTACCATTACTGTAGACCAAATGAAAAGAGGTTATGAGAGAATTTACAATGAAATTCCGGACATTAATCTGGATGTCCCACATTCATACTCTG
TGCTGGAGCGGTTTGTAGAAGAATGTTTTCAGGCTGGAATAATTTCCAAACAACTCAGAGATCTTTGTCCTTCAAGGGGCAGAAAGCGTTTTGTAAGCGA
AGGAGATGGAGGTCGTCTTAAACCAGAGAGCTACTGAATATAAGAACTCTTGCAGTCTTAGATGTTATAAAAATATATATCTGAATTGTAAGAGTTGTTA
GCACAAGTTTTTTTTTTTTTTTTTTTTAAGCACTTGTTTTGGGTACAAGGCATTTCTGACATTTTATAAACCTACATTTAAGGGGAATTTTTAAAGGAAA
TGTTTTTTCTTTTTTTTTTGTTTTTCGAGGGGGCAAGGAGGGACAGAAAAGTAACCTCTTCTTAAGTGGAATATTCTAATAAGCTACCTTTTGTAAGTGC
CATGTTTATTATCTAATCATTCCAAGTTTTGCATTGATGTCTGACTGCCACTCCTTTCTTTCAAGGACAGTGTTTTTTGTAGTAAAATCACTGGTTTATA
CAAAGCTTTATTTAGGGGGTAAAGTTAAGCTGCTAAAACCCCATGTTGGCTGCTGCTGTTGAGATACTGTGCTTTGGGAGTAAAAAAAGAAAGTTATTTC
TTTGTCTTAAAGAATTTTTAAAAAATTAGTCATGAGACTTATTCATCTTTCCAGGGAACATACTGATTGGTCTTAAAAGACTAGACAGTTAAGTAAAAGG
TGGCTGGAACATCTATTTTTCTACAAAACTGGAAAAATGAACCTGGTTCTAGAAGAATGTACACCAAAATAAAACATGTGAAGCAGTATTGATTCTTTAT
TGGGAGTACATTTTTTTAGGTCTCTTAAACTTTAATTTCACACAGTAAATTTTGAATCTCATAAGGAAGCATATTTGAACCTAGTCAATTTAATCTTAGT
GTTCCCTTGAAAACTTTTTTTCCCTACAAAATTTTAAGTGAAAAATACAATAGTAAATTAAGATTACACTGGGGAAAAAAATGCAGGTATCACTTTACTC
CATTGTTATCTGACCTAGAGCTTAATTAAGTTTTAGAAATATGTAATACCTTCCATCATTCCATCATCCTTAAATTCTGTTACCAAATAATGGCTAATGT
TACAAAAAGTTATACTCCAGAGACCCAAAGCTTGACATTTACCTAATGTATGAGAAAATATTACCAATTAACAATAAAGAATGATCATATTTTTAACCTC
TTTTACATAGCCTAATAACTCAGCAAGGCCTCAACGTCTGTGCTAATTTAAACTGCCAAATATTGACTGCAGCAAACAAGAATTATATTCAGAATTTATG
AGGGTACTGTTAGGAGTATACTGCTTACAGGTTTAGATATAGTCTGTTAGAATTAAAACCAAGTTTAGTGTTCATATTTACCTCATGGGCTTTATCAAGC
CCATATTACCTCAGCTTATATATAGTTACCATTTTTAGGTTTTTAATTGTTTGACACTTGGATGATAAATGCAGTCATTTTATTCTCAAGTGCTTAAAAT
TAATGTAATTAAAAGCTTAGCTGACTACAGAATAGGTGAGGGTTTCTTAAAAATGAGATTTAAGGGCTGGGCACGGTGGCTCATGCCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGTGGGCGGATCACTTGAGGTTGGGAGTTCATGACCAGCTTGACCAACATGAAGAAACCCTGTCTCTATTAAAAATACAAAAGTAG
CCAGGCATGGTGGCGCATGCGTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCAGTGAGTCGAGATG
GTGCCATTGCTCTCGTTTGGGCAACAAGAGTGAAACTCTTGTCTCAAAAAAAAAAAAAAATGAGGTTTAAGACAGTTTTGTCATTACTGGTGGGATCTGG
TCACACAAGATAGCATTAAACGTGACATGGCACATAAAATTGGTTAAAAAATTTTGTTTTTTAATTACGTAATGTAAAAGCCCAACAAACACTTTATGCA
AGATTGGAATGTATCTTCAAATTCAGATTTAATAAACATGTAAAGATCCTCTGTA
  • refseq_PDCD4.F1 (forward primer)
  • refseq_PDCD4.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPPGLGQ*APPSRPRVTG*KKTKTNRARRARDS
PRRRQRQKSGVGAG*PGTWASSGGGPRDSEGRFP
LGNLFNQCKRN*GKMDVENEQILNVNPAGYFP*
FSMVLQ*HVIIIKMNSFVE*MTK
YPDNLSDSLF
SGDEENAGTEEIKNEINGNWISASSINEARINAK
AKRRLRKNSSRDSGRGDSVSDSGSDALRSGLTV
PTSPKGRLLDRRSRSGKGRGLPKKGGAGGKGVW
GTPGQVYDVEEVDVKDPNYDDDQENCVYETVVLP
LDERAFEKTLTPIIQEYFEHGDTNEVAEMLRDL
NLGEMKSGVPVLAVSLALEGKASHREMTSKLLS
DLCGTVMSTTDVEKSFDKLLKDLPELALDTPRAP
QLVGQFIARAVGDGILCNTYIDSYKGTVDCVQA
RAALDKATVLLSMSKGGKRKDSVWGSGGGQQSV
NHLVKEIDMLLKEYLLSGDISEAEHCLKELEVPH
FHHELVYEAIIMVLESTGESTFKMILDLLKSLW
KSSTITVDQMKRGYERIYNEIPDINLDVPHSYS
VLERFVEECFQAGIISKQLRDLCPSRGRKRFVSE
GDGGRLKPESY*I*ELLQS*ML*KYISEL*ELL
AQVFFFFFFKHLFWVQGISDIL*TYI*GEFLKE
MFFLFFLFFEGARRDRKVTSS*VEYSNKLPFVSA
MFII*SFQVLH*CLTATPFFQGQCFL**NHWFI
QSFI*GVKLSC*NPMLAAAVEILCFGSKKRKLF
LCLKEFLKN*S*DLFIFPGNILIGLKRLDS*VKG
GWNIYFSTKLEK*TWF*KNVHQNKTCEAVLILY
WEYIFLGLLNFNFTQ*ILNLIRKHI*T*SI*S*
CSLENFFSLQNFK*KIQ**IKITLGKKMQVSLYS
IVI*PRA*LSFRNM*YLPSFHHP*ILLPNNG*C
YKKLYSRDPKLDIYLMYEKILPINNKE*SYF*P
LLHSLITQQGLNVCANLNCQILTAANKNYIQNL*
GYC*EYTAYRFRYSLLELKPSLVFIFTSWALSS
PYYLSLYIVTIFRFLIV*HLDDKCSHFILKCLK
LM*LKA*LTTE*VRVS*K*DLRAGHGGSCL*SQH
FGRPRWADHLRLGVHDQLDQHEETLSLLKIQK*
PGMVAHACNPSYLGG*GRRIA*TWEAEVAVSRD
GAIALVWATRVKLLSQKKKKMRFKTVLSLLVGSG
HTR*H*T*HGT*NWLKNFVF*LRNVKAQQTLYA
RLECIFKFRFNKHVKILC

Frame 1

DHPASANKRRPLAPVLLGRRKQKQTEREGPETL
RGGGRDRRAGSGPADQEPGRAAAGARGILKEDF
H*VICLISASEIKGKWM*KMSRY*M*TLQGIFPN
SPWCFNSMLLS*K*TVLWNR*PN
ILIT*VTLSF
PVMKKMLGLRK*RMK*MEIGFQHPPLTKLELMP
RQKGD*GKTHPGTLAEAIRSATVGVTPLEVD*LC
QPVQREGCWIGDPDLGKEGDYQRKVVQEAKVSG
VHLDRCMMWRRWM*KILTMMMTRRTVFMKL*FC
LWMKGHLRRL*HQSYRNILSMEILMKLRKC*EI*
ILVK*KVEYQCWQYP*HWRGRLVIER*HLSFFL
TFVGQ**AQLMWKNHLINC*KIYLN*HWILLEH
HSWWASLLLELLEMEFYVIPILIVTKEL*IVCRL
ELLWIRLPCF*VCLKVESVKIVCGALEVGSNLS
ITLLKRLICC*KNIYSLETYLKLNIALRNWKYL
IFTMSLYMKLL*WF*SQLEKVHLR*FWIY*SPFG
SLLPLL*TK*KEVMREFTMKFRTLIWMSHIHTL
CWSGL*KNVFRLE*FPNNSEIFVLQGAESVL*A
KEMEVVLNQRATEYKNSCSLRCYKNIYLNCKSC*
HKFFFFFFLSTCFGYKAFLTFYKPTFKGNF*RK
CFFFFFCFSRGQGGTEK*PLLKWNILISYLL*V
PCLLSNHSKFCIDV*LPLLSFKDSVFCSKITGLY
KALFRG*S*AAKTPCWLLLLRYCALGVKKESYF
FVLKNF*KISHETYSSFQGTY*LVLKD*TVK*K
VAGTSIFLQNWKNEPGSRRMYTKIKHVKQY*FFI
GSTFF*VS*TLISHSKF*IS*GSIFEPSQFNLS
VPLKTFFPYKILSEKYNSKLRLHWGKKCRYHFT
PLLSDLELN*VLEICNTFHHSIILKFCYQIMANV
TKSYTPETQSLTFT*CMRKYYQLTIKNDHIFNL
FYIA**LSKASTSVLI*TAKY*LQQTRIIFRIY
EGTVRSILLTGLDIVC*N*NQV*CSYLPHGLYQA
HITSAYI*LPFLGF*LFDTWMINAVILFSSA*N
*CN*KLS*LQNR*GFLKNEI*GLGTVAHACNPS
TLGGRGGRIT*GWEFMTSLTNMKKPCLY*KYKSS
QAWWRMRVIPATWEAEAGELLEPGRQRLQ*VEM
VPLLSFGQQE*NSCLKKKKK*GLRQFCHYWWDL
VTQDSIKRDMAHKIG*KILFFNYVM*KPNKHFMQ
DWNVSSNSDLINM*RSSV

Frame 2

TTRPRPISAALSPPCYWVEENKNKQSEKGQRLS
EAAAETEERGRGRLTRNLGEQRRGPEGF*RKIS
IR*FV*SVQAKLRENGCRK*ADTECKPCRVFSL
ILHGASIACYYHKNEQFCGIDDQI
S**LK*LSLF
R**RKCWD*GNKE*NKWKLDFSILH*RS*N*CQ
GKKATKEKLIPGLWQRRFGQRQWE*RP*KWINC
ANQSKGKVAG*AIQIWERKGTTKERWCRRQRCLG
YTWTGV*CGGGGCERS*L***PGELCL*NCSFA
FG*KGI*EDFNTNHTGIF*AWRY**SCGNVKRF
KSW*NEKWSTSVGSILSIGGEG*S*RDDI*ASF*
PLWDSNEHN*CGKII**IVERST*ISTGYS*ST
TVGGPVYC*SCWRWNFM*YLY**LQRNCRLCAG
*SCSG*GYRASEYV*RWKA*R*CVGLWRWAAICQ
SPC*RD*YAAERIFTLWRHI*S*TLP*GTGSTS
FSP*ACI*SYYNGFRVNWRKYI*DDFGFIKVPL
EVFYHYCRPNEKRL*ENLQ*NSGH*SGCPTFILC
AGAVCRRMFSGWNNFQTTQRSLSFKGQKAFCKR
RRWRSS*TRELLNIRTLAVLDVIKIYI*IVRVV
STSFFFFFF*ALVLGTRHF*HFINLHLRGIFKGN
VFSFFFVFRGGKEGQKSNLFLSGIF**ATFCKC
HVYYLIIPSFALMSDCHSFLSRTVFFVVKSLVY
TKLYLGGKVKLLKPHVGCCC*DTVLWE*KKKVIS
LS*RIFKKLVMRLIHLSREHTDWS*KTRQLSKR
WLEHLFFYKTGKMNLVLEECTPK*NM*SSIDSL
LGVHFFRSLKL*FHTVNFESHKEAYLNLVNLILV
FP*KLFFPTKF*VKNTIVN*DYTGEKNAGITLL
HCYLT*SLIKF*KYVIPSIIPSSLNSVTK*WLM
LQKVILQRPKA*HLPNV*ENITN*Q*RMIIFLTS
FT*PNNSARPQRLC*FKLPNIDCSKQELYSEFM
RVLLGVYCLQV*I*SVRIKTKFSVHIYLMGFIK
PILPQLIYSYHF*VFNCLTLG**MQSFYSQVLKI
NVIKSLADYRIGEGFLKMRFKGWARWLMPVIPA
LWEAEVGGSLEVGSS*PA*PT*RNPVSIKNTKV
ARHGGACV*SQLLGRLRQENCLNLGGRGCSESRW
CHCSRLGNKSETLVSKKKKNEV*DSFVITGGIW
SHKIALNVTWHIKLVKKFCFLIT*CKSPTNTLC
KIGMYLQIQI**TCKDPL

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