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Sequences

Sequence NM_138732

TGCAGGGATGCGGCGGCGGGAGCAGCCGCCCTGACTCGCGGAGCATCCTCCTCGGAGAGGCACCGCGGCGGGGCGGGCGGGCGCGAGGCGGCAGACACCG
CTAGCCCTGGCTCTGCCACCCGTCGGAGACGGGGCGGCCCTGTAGCTCTGCTACCCACCCTCCAGCTTCTGGCGCCCCGAGAACCAGGCATCCCTCCCTG
CTCTTCTGTCGGAGCCCGCGGCGGGGGAGGGGCGCCGCCGCCGCCGCCTGAGGGAAGCCGGCATCTGGGCCTCTGCGCGCCTCGCCCCGCGGCCGGGCCC
ATGGCACTGTGAGCCTGCAAGGGAGCCCCGCTCAGCGCGGGGAGCGCCCGGCCCCCTCCCGCCCCATGCGCCCGCGGCTCTGAAGCCTGAGCGGGGGCCG
GGGGCCGGGCGGGGCCGGGGCCGCCGTAGGCATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTGGCGCTGGCG
GCGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGCTACGCGCGCTGGGCGGGCGCGGCGAGCAGCGGCGAGCTCAGCTTCAGCC
TGCGCACCAACGCCACGCGCGCGCTGCTGCTCTACCTGGACGACGGCGGCGACTGCGACTTCCTGGAGCTGCTGCTGGTGGACGGCCGCCTGCGGCTGCG
CTTCACGCTTTCGTGCGCCGAGCCGGCCACGCTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCTGACCCGCGACGCGCGCCGC
ACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAGCGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGC
CCGACGTGCGCCTCTCGGCGCTTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCCAACCTGAAGCTGGGCGAGCGGCCCCCCGC
GCTGCTGGGCAGCCAGGGCCTGCGCGGCGCCACCGCCGACCCGCTGTGCGCGCCCGCGCGCAACCCCTGCGCCAACGGCGGCCTCTGCACCGTGCTGGCC
CCCGGCGAGGTGGGCTGCGACTGCAGCCACACGGGCTTCGGCGGCAAGTTCTGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAA
ACAGCGAAGGCAAGGAGGAGTTTGTGGCGACCTTCAAAGGCAATGAGTTCTTCTGCTACGACCTGTCACACAACCCCATCCAGAGCAGCACTGATGAGAT
CACACTGGCCTTCCGCACCCTGCAACGCAACGGCCTGATGCTGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCCCTCAAGTCTGGGGCTGTCTGG
CTGGTCATCAACCTAGGCTCAGGTGCCTTCGAGGCCCTTGTGGAACCCGTCAATGGCAAGTTCAACGACAACGCCTGGCACGACGTCCGGGTCACCCGAA
ACCTGCGCCAGCACGCAGGGATTGGACACGCTATGGTGACCATCTCGGTGGACGGGATCCTGACCACCACAGGCTACACGCAGGAGGATTACACCATGCT
GGGCTCTGATGACTTCTTCTACATTGGGGGCAGCCCCAACACAGCTGACCTGCCGGGCTCGCCCGTCAGCAACAACTTCATGGGCTGCCTCAAGGACGTG
GTCTATAAGAACAATGACTTCAAATTGGAACTATCCCGCCTGGCAAAGGAAGGGGACCCCAAGATGAAGCTGCAGGGGGACTTGTCATTCCGCTGTGAGG
ATGTGGCTGCCCTGGACCCTGTGACCTTTGAGAGTCCCGAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCTAAGCGCACTGGCTCCATCTCCCTAGACTT
CCGCACCACCGAGCCCAATGGGCTGCTGCTCTTCAGCCAGGGCCGGCGGGCTGGGGGTGGAGCTGGCAGCCACAGCTCTGCTCAGCGGGCCGACTACTTT
GCCATGGAGCTATTGGACGGCCACCTCTATCTTCTGCTGGACATGGGATCTGGGGGCATCAAGCTGCGGGCATCCAGCCGCAAGGTCAATGATGGCGAGT
GGTGTCACGTGGACTTCCAGAGGGATGGGCGAAAAGGCTCCATCTCAGTGAATAGTCGCAGCACGCCGTTCTTGGCCACTGGAGACAGCGAGATTCTGGA
CCTGGAGAGTGAGCTGTACCTGGGCGGTCTCCCTGAGGGGGGCCGGGTGGACCTGCCCCTGCCCCCAGAGGTGTGGACAGCAGCACTCCGGGCAGGCTAC
GTGGGCTGTGTGCGGGACCTCTTCATAGATGGGCGTAGCCGAGACCTCCGGGGCCTGGCTGAGGCTCAGGGGGCTGTGGGCGTTGCCCCCTTTTGCTCCC
GGGAGACGCTGAAGCAGTGTGCATCTGCCCCCTGTCGCAATGGGGGCGTCTGTCGAGAAGGCTGGAACCGCTTCATCTGTGACTGCATCGGGACCGGCTT
TCTTGGGCGGGTCTGTGAGAGAGAGGCCACGGTCCTGAGCTACGATGGCTCCATGTACATGAAGATCATGCTGCCTAACGCCATGCACACGGAGGCAGAG
GATGTGTCCCTGCGTTTCATGTCCCAGCGGGCCTACGGACTCATGATGGCCACCACTTCCAGGGAGTCTGCCGACACCCTACGCCTGGAGCTGGATGGGG
GGCAGATGAAGCTCACTGTCAACCTCGGTAAAGGCCCCGAAACGCTGTTTGCGGGGCACAAGCTCAATGACAATGAGTGGCACACGGTGAGGGTGGTCCG
GCGTGGCAAGAGCCTGCAGCTGTCTGTGGACAACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGTTCCACAACATTGAGACGGGC
ATCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGGCATCTGAGTGGGCTCGTGTTCAATGGCCAGCCCTACATGGACCAGTGCA
AGGATGGTGACATCACCTACTGTGAGCTCAATGCTCGCTTTGGCCTGCGTGCCATCGTGGCCGATCCCGTCACCTTCAAGAGTCGCAGCAGCTACCTGGC
ACTCGCCACGCTCCAAGCCTATGCTTCCATGCACCTCTTCTTCCAGTTCAAGACCACGGCCCCTGATGGGCTTCTTCTGTTCAACTCGGGCAACGGCAAT
GACTTCATTGTCATCGAGCTGGTCAAGGGGTACATCCACTACGTGTTTGACCTGGGGAATGGCCCGTCCTTGATGAAGGGGAACTCAGACAAACCAGTCA
ATGACAACCAGTGGCACAACGTGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCCCGCACTGTCACGCAGCACTCCAATGGCGC
CCGAAACCTCGATCTCAAAGGGGAGTTGTACATTGGCGGTCTGAGCAAGAATATGTTCAGCAACCTGCCCAAGCTGGTGGCCTCCCGGGATGGCTTTCAG
GGCTGCCTGGCCTCAGTGGACCTCAACGGACGTCTCCCAGACCTCATCGCCGACGCCCTGCACCGCATTGGGCAGGTGGAGAGGGGCTGTGATGGCCCCA
GCACCACCTGCACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGCAGTGGGATGGCTTCACCTGCGACTGCACCATGACTTCCTATGGAGGCCC
TGTCTGCAATGATCCCGGGACCACATACATCTTTGGGAAGGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACGAGGATGGAT
CGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGGGTGGACAGCGCCTCCGGCCTTGGAGACTACCTGCAGCTGCACATCGACC
AGGGCACCGTGGGGGTGATCTTTAACGTGGGCACGGACGACATTACCATCGACGAGCCCAACGCCATAGTAAGCGACGGCAAATACCACGTGGTGCGCTT
CACTCGAAGCGGCGGCAACGCCACCCTGCAGGTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGCCGCCAGCTGACCATCTTCAACAGCCAGGCT
GCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCAGGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTGGCCGCCGAGA
GCGACCCCAATGTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGGCCACCACCCTGCTGGCTGA
CATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCACCACGCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCACCCAGAACACA
GATGACCTGCTGGTGGCCTCTGCTGAGTGTCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTGCCCATTATCA
CGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGTGCCCCCGCCCCCTACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCA
AGACACGCTGCCCCCGCCCGCCGCGCGCCGCCCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCATCGAGGCCTCG
GGCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTTTCCCCTGGTCACGGACCGCACCACCCTCC
TGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACAGATGGGGCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCT
GCCGGCGGGCAAAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTCCTTTGAGCCGCGGAGGCCC
CCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCTGCCCACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCGGGCGCAGTGG
AGGTGATCCGGGAGTCCAGCAGCACCACGGGCATGGTGGTGGGCATTGTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCATGTATAAGTA
CCGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCGGCCCAGAGCAATGGGGCGGTGGTGAAAGAGAAGGCCCCG
GCTGCCCCCAAGACGCCCAGCAAGGCCAAGAAGAACAAAGACAAGGAGTATTATGTCTGAGCCCCCGGCACTGCGCCCCACTGCCAGCTGCCCCTCCTGG
GAGGGCCCGGGAGGAGGGTGCCACCCTCTCCCTGCCAGGGGCCTGGGGACCCTCTCCCTGGCTGCCTCAGGCTTCTCTTACGAAGAGGAAACGCAAAAAA
AGAAAAGGAAAAACCCCGTGCTCGCCCCCTTCCTCCTGCCGTCCACTGCGCGGCCTCGTCAGTCCCGGGGCTGACTGTCCCTCTCAGCTCTGCGCCTGCC
AGGCAGGGCACGTGCTCACAGCCCTGGGTTGATTTATTTTTTTAAGGGGGTAGTTTTATTTTGGTGGGGTTGGGTGGGAAGGAAGGCTGGGGGTTTTGTA
AAGTGTCCACTGCTCGTCCTGTTAATTTTCCTCAATTTTTCTTCTTCTTCCTTCTGTCCCTCCTGCCTTCCTTCTCTTCCCAAGCCCTCCAATCCCCATC
CCAGGCTTGCTGTGTCTCACTGTCCCCACCCTCCTTCCCTACTTCTTTTTTTGTGTGTCTGGTTTCTCCCTTCCTTTCCTCCCTTTGGGTTTCCAGAGTC
GGTGGGAGAAGGGCGGGAGGGTGGGCCCGAGTGGCCCAGTGGGTGGGTGGGGTGGGGTGGGGCAAGTGCCCCAACTCCCCTCACCAGGAGAGGCACCTGC
TTGGTGCCGCCCAGGGAAGGGGCTCAGGCCTGACGGAAGGCCTGTTCTGTGTGTGCCGCCGGGCGACGTGCATTGATGGGGAAGCTGCTGGAGGAGCAGG
GGTGGGGGGTGGGAGGGAGGGGAAAGGCAAATGCAGATATATATTACAGACAAATACTCTAGATTCCACGAGCAGCAGCCTGTGGCACCCGCTGGGCGCG
GGCAGCAGGGAAGAGGGAGCAAGGCATTGTCCACAGACTGCTGGGGTCACTTCTTTGCCCACGGGCTCCCTGCTCCCCCAGTTTTTTTTCTCTCTTTGTT
AACAAATGTGTCTGAGTCTTGGAAAACACCCCAACCCCGGAAATGTGTGGGAAAAAGAAAACAAAAACTTTCCAAATTCCAA
  • refseq_NRXN2.F5 (forward primer)
  • refseq_NRXN2.R5 (reverse primer)
  • Single exon skipping

Frame 0

CRDAAAGAAALTRGASSSERHRGGAGGREAADT
ASPGSATRRRRGGPVALLPTLQLLAPREPGIPPC
SSVGARGGGGAPPPPPEGSRHLGLCAPRPAAGP
MAL*ACKGAPLSAGSARPPPAPCARGSEA*AGA
GGRAGPGPP*AWRPGAGGGRHRRRCCCCCCWRWR
RARTAWSSAAAPGSGLATRAGRARRAAASSASA
CAPTPRARCCSTWTTAATATSWSCCWWTAACGC
ASRFRAPSRPRCSWTRRWPTTAGTWCC*PATRAA
RRWRWTARPAPPRCAPSGARCRWPATCSWAASR
PTCASRRLR*APSSTSRPSAASWPT*SWASGPP
RCWAARACAAPPPTRCARPRATPAPTAASAPCWP
PARWAATAATRASAASSAAKRSTPWKVRLT*R*
TAKARRSLWRPSKAMSSSATTCHTTPSRAALMR
SHWPSAPCNATA*CCIQASRPTTSTCPSSLGLSG
WSST*AQVPSRPLWNPSMASSTTTPGTTSGSPE
TCASTQGLDTLW*PSRWTGS*PPQATRRRITPC
WALMTSSTLGAAPTQLTCRARPSATTSWAASRTW
SIRTMTSNWNYPAWQRKGTPR*SCRGTCHSAVR
MWLPWTL*PLRVPRPLWRCPAGALSALAPSP*T
SAPPSPMGCCSSARAGGLGVELAATALLSGPTTL
PWSYWTATSIFCWTWDLGASSCGHPAARSMMAS
GVTWTSRGMGEKAPSQ*IVAARRSWPLETARFW
TWRVSCTWAVSLRGAGWTCPCPQRCGQQHSGQAT
WAVCGTSS*MGVAETSGAWLRLRGLWALPPFAP
GRR*SSVHLPPVAMGASVEKAGTASSVTASGPA
FLGGSVRERPRS*ATMAPCT*RSCCLTPCTRRQR
MCPCVSCPSGPTDS*WPPLPGSLPTPYAWSWMG
GR*SSLSTSVKAPKRCLRGTSSMTMSGTR*GWS
GVARACSCLWTT*LWRDRWQEPICGWSSTTLRRA
S*RSGGLSPWCPPTSSGI*VGSCSMASPTWTSA
RMVTSPTVSSMLALACVPSWPIPSPSRVAAATW
HSPRSKPMLPCTSSSSSRPRPLMGFFCSTRATAM
TSLSSSWSRGTSTTCLTWGMARP**RGTQTNQS
MTTSGTTWWCPGTQATCTRSRLTPALSRSTPMA
PETSISKGSCTLAV*ARICSATCPSWWPPGMAFR
AAWPQWTSTDVSQTSSPTPCTALGRWRGAVMAP
APPALKSPVPTRASACSSGMASPATAP*LPMEA
LSAMIPGPHTSLGRGERSSPTRGPPMTGPARGWI
AWPWASAPTSGALCWCGWTAPPALETTCSCTST
RAPWG*SLTWARTTLPSTSPTP**ATANTTWCA
SLEAAATPPCRWTAGRSTSGTRQAAS*PSSTARL
PSRSGAGIRAAPSRARCPASTTMGSRCWRWPPR
ATPMCGLRVTCAWWGRGRPCCSVRRPRPPPCWL
TWPPPSWRLPPPWPLPPRAGAAPPH*GTAPPRTQ
MTCWWPLLSVQAMMRTWRSVSPVLEES*YCPLS
RRTP*TPLPWPPDPPSCPRPLPSTPSSREWAPP
KTRCPRPPRAARPLGARARPSGTTATARSPSRPR
ASPPGRSLTPASPPRTTRTFTPPFPWSRTAPPS
CHPANPLPGPTSGQMGPRAPLGCCLPPPPRPPT
CRRAK*TTETRFSPCWRTRPWGPGPPRPLSRGGP
LPCAPA*PQPPASPICPQPTPQGLGSGARRAQW
R*SGSPAAPRAWWWALWRRRRSASSSSSTPCIS
TAIVMRAPTRWTRAETTSVTRPRAMGRW*KRRPR
LPPRRPARPRRTKTRSIMSEPPALRPTASCPSW
EGPGGGCHPLPARGLGTLSLAASGFSYEEETQK
KKRKNPVLAPFLLPSTARPRQSRG*LSLSALRLP
GRARAHSPGLIYFFKGVVLFWWGWVGRKAGGFV
KCPLLVLLIFLNFSSSSFCPSCLPSLPKPSNPH
PRLAVSHCPHPPSLLLFLCVWFLPSFPPFGFPES
VGEGREGGPEWPSGWVGWGGASAPTPLTRRGTC
LVPPREGAQA*RKACSVCAAGRRALMGKLLEEQ
GWGVGGRGKANADIYYRQIL*IPRAAACGTRWAR
AAGKREQGIVHRLLGSLLCPRAPCSPSFFSLFV
NKCV*VLENTPTPEMCGKKKTKTFQIP

Frame 1

AGMRRREQPP*LAEHPPRRGTAAGRAGARRQTP
LALALPPVGDGAAL*LCYPPSSFWRPENQASLP
ALLSEPAAGEGRRRRRLREAGIWASARLAPRPGP
WHCEPAREPRSARGAPGPLPPHAPAALKPERGP
GAGRGRGRRRHGVREPVAADTAAAAVAAAAGAG
GARGRPGVRRRPRAVGSLRALGGRGEQRRAQLQP
AHQRHARAAALPGRRRRLRLPGAAAGGRPPAAA
LHAFVRRAGHAAAGHAGGRRPLAHGAADPRRAP
HGAGGGRRGPRRRGALQAARDAGGQRPVRGRHPA
RRAPLGAYAEHRQVRAALPRPLGQPEAGRAAPR
AAGQPGPARRHRRPAVRARAQPLRQRRPLHRAG
PRRGGLRLQPHGLRRQVLQRRGAPHGRSGSPDVK
QRRQGGVCGDLQRQ*VLLLRPVTQPHPEQH**D
HTGLPHPATQRPDAAYRQVGRLRQPVPQVWGCL
AGHQPRLRCLRGPCGTRQWQVQRQRLARRPGHPK
PAPARRDWTRYGDHLGGRDPDHHRLHAGGLHHA
GL**LLLHWGQPQHS*PAGLARQQQLHGLPQGR
GL*EQ*LQIGTIPPGKGRGPQDEAAGGLVIPL*G
CGCPGPCDL*ESRGLCGAAPLER*AHWLHLPRL
PHHRAQWAAALQPGPAGWGWSWQPQLCSAGRLL
CHGAIGRPPLSSAGHGIWGHQAAGIQPQGQ*WRV
VSRGLPEGWAKRLHLSE*SQHAVLGHWRQRDSG
PGE*AVPGRSP*GGPGGPAPAPRGVDSSTPGRL
RGLCAGPLHRWA*PRPPGPG*GSGGCGRCPLLLP
GDAEAVCICPLSQWGRLSRRLEPLHL*LHRDRL
SWAGL*ERGHGPELRWLHVHEDHAA*RHAHGGR
GCVPAFHVPAGLRTHDGHHFQGVCRHPTPGAGWG
ADEAHCQPR*RPRNAVCGAQAQ*Q*VAHGEGGP
AWQEPAAVCGQRDCGGTDGRSPYAAGVPQH*DG
HHDGAAVYLRGALQLHRASEWARVQWPALHGPVQ
GW*HHLL*AQCSLWPACHRGRSRHLQESQQLPG
TRHAPSLCFHAPLLPVQDHGP*WASSVQLGQRQ
*LHCHRAGQGVHPLRV*PGEWPVLDEGELRQTSQ
*QPVAQRGGVQGPRQRAHAQD*LPHCHAALQWR
PKPRSQRGVVHWRSEQEYVQQPAQAGGLPGWLS
GLPGLSGPQRTSPRPHRRRPAPHWAGGEGL*WPQ
HHLH*RVLCQPGRLLAAVGWLHLRLHHDFLWRP
CLQ*SRDHIHLWEGGSAHHLHVAPQ*QAQHEDG
SPGRGLQHPPAERCAGAGGQRLRPWRLPAAAHRP
GHRGGDL*RGHGRHYHRRAQRHSKRRQIPRGAL
HSKRRQRHPAGGQLAGQRAVPGRPPADHLQQPG
CHQDRGPGSGPPLPGPGVRPLLQWAQGAGAGRRE
RPQCAD*GSPAPGGGGAVRAAQCGDHGHHPAG*
HGHHHHGDYHHHGHYHHAPGPLPHTEGQHHPEH
R*PAGGLC*VSKR**GPGGV*AQYWRRVNIAHYH
GGLLRPPSRGHPIPLRAPAPYLLPLPHGSGRHP
RHAAPARRAPPALWGPVPGRAGRQRLRGAHRGL
GLRLRGGL*LQPPPHGRRGLLHHLSPGHGPHHPP
VTPQTRSPAQPQDRWGHGRPWGAVCPLRPGPQP
AGGQNEPPRPASALAGEPALGARGPHVL*AAEA
PSPAPRRDLSPRLPPSAHSQPHRAWGAGPAGRSG
GDPGVQQHHGHGGGHCGGGGALHPHPPLRHV*V
PQS**GLLPGGPEPKLHQ*LGPEQWGGGEREGP
GCPQDAQQGQEEQRQGVLCLSPRHCAPLPAAPPG
RAREEGATLSLPGAWGPSPWLPQASLTKRKRKK
RKGKTPCSPPSSCRPLRGLVSPGADCPSQLCAC
QAGHVLTALG*FIFLRG*FYFGGVGWEGRLGVL*
SVHCSSC*FSSIFLLLPSVPPAFLLFPSPPIPI
PGLLCLTVPTLLPYFFFCVSGFSLPFLPLGFQS
RWEKGGRVGPSGPVGGWGGVGQVPQLPSPGEAPA
WCRPGKGLRPDGRPVLCVPPGDVH*WGSCWRSR
GGGWEGGERQMQIYITDKYSRFHEQQPVAPAGR
GQQGRGSKALSTDCWGHFFAHGLPAPPVFFLSLL
TNVSESWKTPQPRKCVGKRKQKLSKFQ

Frame 2

QGCGGGSSRPDSRSILLGEAPRRGGRARGGRHR
*PWLCHPSETGRPCSSATHPPASGAPRTRHPSL
LFCRSPRRGRGAAAAA*GKPASGPLRASPRGRA
HGTVSLQGSPAQRGERPAPSRPMRPRL*SLSGGR
GPGGAGAAVGMASGSRWRPTPPPLLLLLLLALA
ARADGLEFGGGPGQWARYARWAGAASSGELSFS
LRTNATRALLLYLDDGGDCDFLELLLVDGRLRLR
FTLSCAEPATLQLDTPVADDRWHMVLLTRDARR
TALAVDGEARAAEVRSKRREMQVASDLFVGGIP
PDVRLSALTLSTVKYEPPFRGLLANLKLGERPPA
LLGSQGLRGATADPLCAPARNPCANGGLCTVLA
PGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTL
NSEGKEEFVATFKGNEFFCYDLSHNPIQSSTDEI
TLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVW
LVINLGSGAFEALVEPVNGKFNDNAWHDVRVTR
NLRQHAGIGHAMVTISVDGILTTTGYTQEDYTML
GSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDV
VYKNNDFKLELSRLAKEGDPKMKLQGDLSFRCE
DVAALDPVTFESPEAFVALPRWSAKRTGSISLDF
RTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYF
AMELLDGHLYLLLDMGSGGIKLRASSRKVNDGE
WCHVDFQRDGRKGSISVNSRSTPFLATGDSEILD
LESELYLGGLPEGGRVDLPLPPEVWTAALRAGY
VGCVRDLFIDGRSRDLRGLAEAQGAVGVAPFCS
RETLKQCASAPCRNGGVCREGWNRFICDCIGTGF
LGRVCEREATVLSYDGSMYMKIMLPNAMHTEAE
DVSLRFMSQRAYGLMMATTSRESADTLRLELDG
GQMKLTVNLGKGPETLFAGHKLNDNEWHTVRVVR
RGKSLQLSVDNVTVEGQMAGAHMRLEFHNIETG
IMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC
KDGDITYCELNARFGLRAIVADPVTFKSRSSYLA
LATLQAYASMHLFFQFKTTAPDGLLLFNSGNGN
DFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPV
NDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGA
RNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQ
GCLASVDLNGRLPDLIADALHRIGQVERGCDGP
STTCTEESCANQGVCLQQWDGFTCDCTMTSYGGP
VCNDPGTTYIFGKGGALITYTWPPNDRPSTRMD
RLAVGFSTHQRSAVLVRVDSASGLGDYLQLHID
QGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRF
TRSGGNATLQVDSWPVNERYPAGRQLTIFNSQA
AIKIGGRDQGRPFQGQVSGLYYNGLKVLALAAE
SDPNVRTEGHLRLVGEGPSVLLSAETTATTLLAD
MATTIMETTTTMATTTTRRGRSPTLRDSTTQNT
DDLLVASAECPSDDEDLEECEPSTGGELILPII
TEDSLDPPPVATRSPFVPPPPTFYPFLTGVGATQ
DTLPPPAARRPPSGGPCQAERDDSDCEEPIEAS
GFASGEVFDSSLPPTDDEDFYTTFPLVTDRTTL
LSPRKPAPRPNLRTDGATGAPGVLFAPSAPAPNL
PAGKMNHRDPLQPLLENPPLGPGAPTSFEPRRP
PPLRPGVTSAPGFPHLPTANPTGPGERGPPGAV
EVIRESSSTTGMVVGIVAAAALCILILLYAMYKY
RNRDEGSYQVDQSRNYISNSAQSNGAVVKEKAP
AAPKTPSKAKKNKDKEYYV*APGTAPHCQLPLL
GGPGRRVPPSPCQGPGDPLPGCLRLLLRRGNAKK
EKEKPRARPLPPAVHCAASSVPGLTVPLSSAPA
RQGTCSQPWVDLFF*GGSFILVGLGGKEGWGFC
KVSTARPVNFPQFFFFFLLSLLPSFSSQALQSPS
QACCVSLSPPSFPTSFFVCLVSPFLSSLWVSRV
GGRRAGGWARVAQWVGGVGWGKCPNSPHQERHL
LGAAQGRGSGLTEGLFCVCRRATCIDGEAAGGAG
VGGGREGKGKCRYILQTNTLDSTSSSLWHPLGA
GSREEGARHCPQTAGVTSLPTGSLLPQFFFSLC
*QMCLSLGKHPNPGNVWEKENKNFPNS

Sequence NM_138734

GGCAGCAGCGGCGCGGCCGGCCCCAGTCGCCGTCGGTCTCCCGCCTTCGGGGGAACCAGGTCTCCGTCCCTCTTCTCTCCTCCAGCCCGCACCGCCCCGC
TCCCCAGCTCGGTTTTTCCGCAGGATTTCCCTCGCTCTCCCCTCCCTGCTTGGCCCCCGCGCTCCCCTCCCTCTCCACTCGGCACCATGCCCCCTCCCCC
GGGCGCTCCCCCGGGTTTCTGACGGCCCTCTGCGCCGCTCCGACCCCGCCGGGATGCAGAGAGACCCCTAGCTCCTCGCGATGGACCCAGGCATCCTGGA
CCTTGGCGTTGCCGCTCCGCGGACCCCCGATTTCCCGGCGGGATCCAGTTGATTTTGTTGGCTCCGGACCGAGGCTTGGGCCCTGGTTTACCTCCGCTTC
ATCCCTACCCCGCTCCCGGAGCTCGGAGCCGGAGGGGGGCTTCGCGGGGCTGCGCAGCCCCGCGTCCCCGCCCCCGGCCATGGGGCTGTGAGGCGGTCGC
CCCCGGGCCGAAATGCCCCCCGGGGGGAGCGGGCCGGGGGGGTGCCCGCGCCGCCCCCCGGCCCTGGCTGGGCCCCTGCCGCCGCCTCCACCGCCGCCGC
CGCCACCTCTGCTGCCGCTGTTGCCGCTGTTGCTGCTGTTGCTGCTGGGGGCGGCCGAGGGGGCCCGGGTCTCCTCCAGCCTCAGCACCACCCACCACGT
CCACCACTTCCACAGCAAGCACGGCACCGTGCCCATCGCCATCAACCGCATGCCCTTCCTCACCCGCGGCGGCCACGCCGGGACCACATACATCTTTGGG
AAGGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACAGGCCCAGCACGAGGATGGATCGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCG
CTGTGCTGGTGCGGGTGGACAGCGCCTCCGGCCTTGGAGACTACCTGCAGCTGCACATCGACCAGGGCACCGTGGGGGTGATCTTTAACGTGGGCACGGA
CGACATTACCATCGACGAGCCCAACGCCATAGTAAGCGACGGCAAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGCCACCCTGCAGGTGGAC
AGCTGGCCGGTCAACGAGCGGTACCCGGCAGGAAACTTTGATAACGAGCGCCTGGCGATTGCTAGACAGAGAATCCCCTACCGGCTTGGTCGAGTAGTAG
ATGAGTGGCTGCTCGACAAAGGCCGCCAGCTGACCATCTTCAACAGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCAGGGCCA
GGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTGGCCGCCGAGAGCGACCCCAATGTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAG
GGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGGCCACCACCCTGCTGGCTGACATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCA
CCACGCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCACCCAGAACACAGATGACCTGCTGGTGGCCTCTGCTGAGTGTCCAAGCGATGATGAGGA
CCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTGCCCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTC
GTGCCCCCGCCCCCTACCTTCTACCCCTTCCTCACGGGAGTGGGCGCCACCCAAGACACGCTGCCCCCGCCCGCCGCGCGCCGCCCGCCCTCTGGGGGCC
CGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCATCGAGGCCTCGGGCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGA
CGACGAGGACTTTTACACCACCTTTCCCCTGGTCACGGACCGCACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACAGATGGG
GCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGGCCCCCAACCTGCCGGCGGGCAAAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGG
AGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTCCTTTGAGCCGCGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCT
GCCCACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCGGGCGCAGTGGAGGTGATCCGGGAGTCCAGCAGCACCACGGGCATGGTGGTGGGCATT
GTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCATGTATAAGTACCGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACT
ACATCAGTAACTCGGCCCAGAGCAATGGGGCGGTGGTGAAAGAGAAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAAGAAGAACAAAGACAAGGA
GTATTATGTCTGAGCCCCCGGCACTGCGCCCCACTGCCAGCTGCCCCTCCTGGGAGGGCCCGGGAGGAGGGTGCCACCCTCTCCCTGCCAGGGGCCTGGG
GACCCTCTCCCTGGCTGCCTCAGGCTTCTCTTACGAAGAGGAAACGCAAAAAAAGAAAAGGAAAAACCCCGTGCTCGCCCCCTTCCTCCTGCCGTCCACT
GCGCGGCCTCGTCAGTCCCGGGGCTGACTGTCCCTCTCAGCTCTGCGCCTGCCAGGCAGGGCACGTGCTCACAGCCCTGGGTTGATTTATTTTTTTAAGG
GGGTAGTTTTATTTTGGTGGGGTTGGGTGGGAAGGAAGGCTGGGGGTTTTGTAAAGTGTCCACTGCTCGTCCTGTTAATTTTCCTCAATTTTTCTTCTTC
TTCCTTCTGTCCCTCCTGCCTTCCTTCTCTTCCCAAGCCCTCCAATCCCCATCCCAGGCTTGCTGTGTCTCACTGTCCCCACCCTCCTTCCCTACTTCTT
TTTTTGTGTGTCTGGTTTCTCCCTTCCTTTCCTCCCTTTGGGTTTCCAGAGTCGGTGGGAGAAGGGCGGGAGGGTGGGCCCGAGTGGCCCAGTGGGTGGG
TGGGGTGGGGTGGGGCAAGTGCCCCAACTCCCCTCACCAGGAGAGGCACCTGCTTGGTGCCGCCCAGGGAAGGGGCTCAGGCCTGACGGAAGGCCTGTTC
TGTGTGTGCCGCCGGGCGACGTGCATTGATGGGGAAGCTGCTGGAGGAGCAGGGGTGGGGGGTGGGAGGGAGGGGAAAGGCAAATGCAGATATATATTAC
AGACAAATACTCTAGATTCCACGAGCAGCAGCCTGTGGCACCCGCTGGGCGCGGGCAGCAGGGAAGAGGGAGCAAGGCATTGTCCACAGACTGCTGGGGT
CACTTCTTTGCCCACGGGCTCCCTGCTCCCCCAGTTTTTTTTCTCTCTTTGTTAACAAATGTGTCTGAGTCTTGGAAAACACCCCAACCCCGGAAATGTG
TGGGAAAAAGAAAACAAAAACTTTCCAAATTCCAA
  • refseq_NRXN2.F5 (forward primer)
  • refseq_NRXN2.R5 (reverse primer)
  • Single exon skipping

Frame 0

GSSGAAGPSRRRSPAFGGTRSPSLFSPPARTAP
LPSSVFPQDFPRSPLPAWPPRSPPSPLGTMPPPP
GAPPGF*RPSAPLRPRRDAERPLAPRDGPRHPG
PWRCRSADPRFPGGIQLILLAPDRGLGPGLPPL
HPYPAPGARSRRGASRGCAAPRPRPRPWGCEAVA
PGPKCPPGGAGRGGARAAPRPWLGPCRRLHRRR
RHLCCRCCRCCCCCCWGRPRGPGSPPASAPPTT
STTSTASTAPCPSPSTACPSSPAAATPGPHTSLG
RGERSSPTRGPPMTGPARGWIAWPWASAPTSGA
LCWCGWTAPPALETTCSCTSTRAPWG*SLTWAR
TTLPSTSPTP**ATANTTWCASLEAAATPPCRWT
AGRSTSGTRQETLITSAWRLLDRESPTGLVE**
MSGCSTKAAS*PSSTARLPSRSGAGIRAAPSRA
RCPASTTMGSRCWRWPPRATPMCGLRVTCAWWGR
GRPCCSVRRPRPPPCWLTWPPPSWRLPPPWPLP
PRAGAAPPH*GTAPPRTQMTCWWPLLSVQAMMR
TWRSVSPVLEES*YCPLSRRTP*TPLPWPPDPPS
CPRPLPSTPSSREWAPPKTRCPRPPRAARPLGA
RARPSGTTATARSPSRPRASPPGRSLTPASPPR
TTRTFTPPFPWSRTAPPSCHPANPLPGPTSGQMG
PRAPLGCCLPPPPRPPTCRRAK*TTETRFSPCW
RTRPWGPGPPRPLSRGGPLPCAPA*PQPPASPI
CPQPTPQGLGSGARRAQWR*SGSPAAPRAWWWAL
WRRRRSASSSSSTPCISTAIVMRAPTRWTRAET
TSVTRPRAMGRW*KRRPRLPPRRPARPRRTKTR
SIMSEPPALRPTASCPSWEGPGGGCHPLPARGLG
TLSLAASGFSYEEETQKKKRKNPVLAPFLLPST
ARPRQSRG*LSLSALRLPGRARAHSPGLIYFFK
GVVLFWWGWVGRKAGGFVKCPLLVLLIFLNFSSS
SFCPSCLPSLPKPSNPHPRLAVSHCPHPPSLLL
FLCVWFLPSFPPFGFPESVGEGREGGPEWPSGW
VGWGGASAPTPLTRRGTCLVPPREGAQA*RKACS
VCAAGRRALMGKLLEEQGWGVGGRGKANADIYY
RQIL*IPRAAACGTRWARAAGKREQGIVHRLLG
SLLCPRAPCSPSFFSLFVNKCV*VLENTPTPEMC
GKKKTKTFQIP

Frame 1

AAAARPAPVAVGLPPSGEPGLRPSSLLQPAPPR
SPARFFRRISLALPSLLGPRAPLPLHSAPCPLP
RALPRVSDGPLRRSDPAGMQRDP*LLAMDPGILD
LGVAAPRTPDFPAGSS*FCWLRTEAWALVYLRF
IPTPLPELGAGGGLRGAAQPRVPAPGHGAVRRS
PPGRNAPRGERAGGVPAPPPGPGWAPAAASTAAA
ATSAAAVAAVAAVAAGGGRGGPGLLQPQHHPPR
PPLPQQARHRAHRHQPHALPHPRRPRRDHIHLW
EGGSAHHLHVAPQ*QAQHEDGSPGRGLQHPPAER
CAGAGGQRLRPWRLPAAAHRPGHRGGDL*RGHG
RHYHRRAQRHSKRRQIPRGALHSKRRQRHPAGG
QLAGQRAVPGRKL**RAPGDC*TENPLPAWSSSR
*VAARQRPPADHLQQPGCHQDRGPGSGPPLPGP
GVRPLLQWAQGAGAGRRERPQCAD*GSPAPGGG
GAVRAAQCGDHGHHPAG*HGHHHHGDYHHHGHYH
HAPGPLPHTEGQHHPEHR*PAGGLC*VSKR**G
PGGV*AQYWRRVNIAHYHGGLLRPPSRGHPIPL
RAPAPYLLPLPHGSGRHPRHAAPARRAPPALWGP
VPGRAGRQRLRGAHRGLGLRLRGGL*LQPPPHG
RRGLLHHLSPGHGPHHPPVTPQTRSPAQPQDRW
GHGRPWGAVCPLRPGPQPAGGQNEPPRPASALAG
EPALGARGPHVL*AAEAPSPAPRRDLSPRLPPS
AHSQPHRAWGAGPAGRSGGDPGVQQHHGHGGGH
CGGGGALHPHPPLRHV*VPQS**GLLPGGPEPKL
HQ*LGPEQWGGGEREGPGCPQDAQQGQEEQRQG
VLCLSPRHCAPLPAAPPGRAREEGATLSLPGAW
GPSPWLPQASLTKRKRKKRKGKTPCSPPSSCRPL
RGLVSPGADCPSQLCACQAGHVLTALG*FIFLR
G*FYFGGVGWEGRLGVL*SVHCSSC*FSSIFLL
LPSVPPAFLLFPSPPIPIPGLLCLTVPTLLPYFF
FCVSGFSLPFLPLGFQSRWEKGGRVGPSGPVGG
WGGVGQVPQLPSPGEAPAWCRPGKGLRPDGRPV
LCVPPGDVH*WGSCWRSRGGGWEGGERQMQIYIT
DKYSRFHEQQPVAPAGRGQQGRGSKALSTDCWG
HFFAHGLPAPPVFFLSLLTNVSESWKTPQPRKC
VGKRKQKLSKFQ

Frame 2

QQRRGRPQSPSVSRLRGNQVSVPLLSSSPHRPA
PQLGFSAGFPSLSPPCLAPALPSLSTRHHAPSP
GRSPGFLTALCAAPTPPGCRETPSSSRWTQASW
TLALPLRGPPISRRDPVDFVGSGPRLGPWFTSAS
SLPRSRSSEPEGGFAGLRSPASPPPAMGL*GGR
PRAEMPPGGSGPGGCPRRPPALAGPLPPPPPPP
PPPLLPLLPLLLLLLLGAAEGARVSSSLSTTHHV
HHFHSKHGTVPIAINRMPFLTRGGHAGTTYIFG
KGGALITYTWPPNDRPSTRMDRLAVGFSTHQRS
AVLVRVDSASGLGDYLQLHIDQGTVGVIFNVGTD
DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD
SWPVNERYPAGNFDNERLAIARQRIPYRLGRVV
DEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQ
VSGLYYNGLKVLALAAESDPNVRTEGHLRLVGE
GPSVLLSAETTATTLLADMATTIMETTTTMATT
TTRRGRSPTLRDSTTQNTDDLLVASAECPSDDED
LEECEPSTGGELILPIITEDSLDPPPVATRSPF
VPPPPTFYPFLTGVGATQDTLPPPAARRPPSGG
PCQAERDDSDCEEPIEASGFASGEVFDSSLPPTD
DEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDG
ATGAPGVLFAPSAPAPNLPAGKMNHRDPLQPLL
ENPPLGPGAPTSFEPRRPPPLRPGVTSAPGFPHL
PTANPTGPGERGPPGAVEVIRESSSTTGMVVGI
VAAAALCILILLYAMYKYRNRDEGSYQVDQSRN
YISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKE
YYV*APGTAPHCQLPLLGGPGRRVPPSPCQGPG
DPLPGCLRLLLRRGNAKKEKEKPRARPLPPAVH
CAASSVPGLTVPLSSAPARQGTCSQPWVDLFF*G
GSFILVGLGGKEGWGFCKVSTARPVNFPQFFFF
FLLSLLPSFSSQALQSPSQACCVSLSPPSFPTS
FFVCLVSPFLSSLWVSRVGGRRAGGWARVAQWVG
GVGWGKCPNSPHQERHLLGAAQGRGSGLTEGLF
CVCRRATCIDGEAAGGAGVGGGREGKGKCRYIL
QTNTLDSTSSSLWHPLGAGSREEGARHCPQTAGV
TSLPTGSLLPQFFFSLC*QMCLSLGKHPNPGNV
WEKENKNFPNS

Sequence NM_015080

TGCAGGGATGCGGCGGCGGGAGCAGCCGCCCTGACTCGCGGAGCATCCTCCTCGGAGAGGCACCGCGGCGGGGCGGGCGGGCGCGAGGCGGCAGACACCG
CTAGCCCTGGCTCTGCCACCCGTCGGAGACGGGGCGGCCCTGTAGCTCTGCTACCCACCCTCCAGCTTCTGGCGCCCCGAGAACCAGGCATCCCTCCCTG
CTCTTCTGTCGGAGCCCGCGGCGGGGGAGGGGCGCCGCCGCCGCCGCCTGAGGGAAGCCGGCATCTGGGCCTCTGCGCGCCTCGCCCCGCGGCCGGGCCC
ATGGCACTGTGAGCCTGCAAGGGAGCCCCGCTCAGCGCGGGGAGCGCCCGGCCCCCTCCCGCCCCATGCGCCCGCGGCTCTGAAGCCTGAGCGGGGGCCG
GGGGCCGGGCGGGGCCGGGGCCGCCGTAGGCATGGCGTCCGGGAGCCGGTGGCGGCCGACACCGCCGCCGCTGCTGTTGCTGCTGCTGCTGGCGCTGGCG
GCGCGCGCGGACGGCCTGGAGTTCGGCGGCGGCCCCGGGCAGTGGGCTCGCTACGCGCGCTGGGCGGGCGCGGCGAGCAGCGGCGAGCTCAGCTTCAGCC
TGCGCACCAACGCCACGCGCGCGCTGCTGCTCTACCTGGACGACGGCGGCGACTGCGACTTCCTGGAGCTGCTGCTGGTGGACGGCCGCCTGCGGCTGCG
CTTCACGCTTTCGTGCGCCGAGCCGGCCACGCTGCAGCTGGACACGCCGGTGGCCGACGACCGCTGGCACATGGTGCTGCTGACCCGCGACGCGCGCCGC
ACGGCGCTGGCGGTGGACGGCGAGGCCCGCGCCGCCGAGGTGCGCTCCAAGCGGCGCGAGATGCAGGTGGCCAGCGACCTGTTCGTGGGCGGCATCCCGC
CCGACGTGCGCCTCTCGGCGCTTACGCTGAGCACCGTCAAGTACGAGCCGCCCTTCCGCGGCCTCTTGGCCAACCTGAAGCTGGGCGAGCGGCCCCCCGC
GCTGCTGGGCAGCCAGGGCCTGCGCGGCGCCACCGCCGACCCGCTGTGCGCGCCCGCGCGCAACCCCTGCGCCAACGGCGGCCTCTGCACCGTGCTGGCC
CCCGGCGAGGTGGGCTGCGACTGCAGCCACACGGGCTTCGGCGGCAAGTTCTGCAGCGAAGAGGAGCACCCCATGGAAGGTCCGGCTCACCTGACGTTAA
ACAGCGAAGTAGGGTCCTTACTGTTCTCCGAGGGGGGGGCCGGGAGAGGAGGAGCCGGCGATGTGCACCAGCCAACAAAAGGCAAGGAGGAGTTTGTGGC
GACCTTCAAAGGCAATGAGTTCTTCTGCTACGACCTGTCACACAACCCCATCCAGAGCAGCACTGATGAGATCACACTGGCCTTCCGCACCCTGCAACGC
AACGGCCTGATGCTGCATACAGGCAAGTCGGCCGACTACGTCAACCTGTCCCTCAAGTCTGGGGCTGTCTGGCTGGTCATCAACCTAGGCTCAGGTGCCT
TCGAGGCCCTTGTGGAACCCGTCAATGGCAAGTTCAACGACAACGCCTGGCACGACGTCCGGGTCACCCGAAACCTGCGCCAGCACGCAGGGATTGGACA
CGCTATGGTAAACAAACTGCATTATCTGGTGACCATCTCGGTGGACGGGATCCTGACCACCACAGGCTACACGCAGGAGGATTACACCATGCTGGGCTCT
GATGACTTCTTCTACATTGGGGGCAGCCCCAACACAGCTGACCTGCCGGGCTCGCCCGTCAGCAACAACTTCATGGGCTGCCTCAAGGACGTGGTCTATA
AGAACAATGACTTCAAATTGGAACTATCCCGCCTGGCAAAGGAAGGGGACCCCAAGATGAAGCTGCAGGGGGACTTGTCATTCCGCTGTGAGGATGTGGC
TGCCCTGGACCCTGTGACCTTTGAGAGTCCCGAGGCCTTTGTGGCGCTGCCCCGCTGGAGCGCTAAGCGCACTGGCTCCATCTCCCTAGACTTCCGCACC
ACCGAGCCCAATGGGCTGCTGCTCTTCAGCCAGGGCCGGCGGGCTGGGGGTGGAGCTGGCAGCCACAGCTCTGCTCAGCGGGCCGACTACTTTGCCATGG
AGCTATTGGACGGCCACCTCTATCTTCTGCTGGACATGGGATCTGGGGGCATCAAGCTGCGGGCATCCAGCCGCAAGGTCAATGATGGCGAGTGGTGTCA
CGTGGACTTCCAGAGGGATGGGCGAAAAGGCTCCATCTCAGTGAATAGTCGCAGCACGCCGTTCTTGGCCACTGGAGACAGCGAGATTCTGGACCTGGAG
AGTGAGCTGTACCTGGGCGGTCTCCCTGAGGGGGGCCGGGTGGACCTGCCCCTGCCCCCAGAGGTGTGGACAGCAGCACTCCGGGCAGGCTACGTGGGCT
GTGTGCGGGACCTCTTCATAGATGGGCGTAGCCGAGACCTCCGGGGCCTGGCTGAGGCTCAGGGGGCTGTGGGCGTTGCCCCCTTTTGCTCCCGGGAGAC
GCTGAAGCAGTGTGCATCTGCCCCCTGTCGCAATGGGGGCGTCTGTCGAGAAGGCTGGAACCGCTTCATCTGTGACTGCATCGGGACCGGCTTTCTTGGG
CGGGTCTGTGAGAGAGAGGCCACGGTCCTGAGCTACGATGGCTCCATGTACATGAAGATCATGCTGCCTAACGCCATGCACACGGAGGCAGAGGATGTGT
CCCTGCGTTTCATGTCCCAGCGGGCCTACGGACTCATGATGGCCACCACTTCCAGGGAGTCTGCCGACACCCTACGCCTGGAGCTGGATGGGGGGCAGAT
GAAGCTCACTGTCAACCTCGACTGCCTGCGCGTCGGCTGCGCACCCAGTAAAGGCCCCGAAACGCTGTTTGCGGGGCACAAGCTCAATGACAATGAGTGG
CACACGGTGAGGGTGGTCCGGCGTGGCAAGAGCCTGCAGCTGTCTGTGGACAACGTGACTGTGGAGGGACAGATGGCAGGAGCCCATATGCGGCTGGAGT
TCCACAACATTGAGACGGGCATCATGACGGAGCGGCGGTTTATCTCCGTGGTGCCCTCCAACTTCATCGGGCATCTGAGTGGGCTCGTGTTCAATGGCCA
GCCCTACATGGACCAGTGCAAGGATGGTGACATCACCTACTGTGAGCTCAATGCTCGCTTTGGCCTGCGTGCCATCGTGGCCGATCCCGTCACCTTCAAG
AGTCGCAGCAGCTACCTGGCACTCGCCACGCTCCAAGCCTATGCTTCCATGCACCTCTTCTTCCAGTTCAAGACCACGGCCCCTGATGGGCTTCTTCTGT
TCAACTCGGGCAACGGCAATGACTTCATTGTCATCGAGCTGGTCAAGGGGTACATCCACTACGTGTTTGACCTGGGGAATGGCCCGTCCTTGATGAAGGG
GAACTCAGACAAACCAGTCAATGACAACCAGTGGCACAACGTGGTGGTGTCCAGGGACCCAGGCAACGTGCACACGCTCAAGATTGACTCCCGCACTGTC
ACGCAGCACTCCAATGGCGCCCGAAACCTCGATCTCAAAGGGGAGTTGTACATTGGCGGTCTGAGCAAGAATATGTTCAGCAACCTGCCCAAGCTGGTGG
CCTCCCGGGATGGCTTTCAGGGCTGCCTGGCCTCAGTGGACCTCAACGGACGTCTCCCAGACCTCATCGCCGACGCCCTGCACCGCATTGGGCAGGTGGA
GAGGGGCTGTGATGGCCCCAGCACCACCTGCACTGAAGAGTCCTGTGCCAACCAGGGCGTCTGCTTGCAGCAGTGGGATGGCTTCACCTGCGACTGCACC
ATGACTTCCTATGGAGGCCCTGTCTGCAATGATCCCGGGACCACATACATCTTTGGGAAGGGGGGAGCGCTCATCACCTACACGTGGCCCCCCAATGACA
GGCCCAGCACGAGGATGGATCGCCTGGCCGTGGGCTTCAGCACCCACCAGCGGAGCGCTGTGCTGGTGCGGGTGGACAGCGCCTCCGGCCTTGGAGACTA
CCTGCAGCTGCACATCGACCAGGGCACCGTGGGGGTGATCTTTAACGTGGGCACGGACGACATTACCATCGACGAGCCCAACGCCATAGTAAGCGACGGC
AAATACCACGTGGTGCGCTTCACTCGAAGCGGCGGCAACGCCACCCTGCAGGTGGACAGCTGGCCGGTCAACGAGCGGTACCCGGCAGGAAACTTTGATA
ACGAGCGCCTGGCGATTGCTAGACAGAGAATCCCCTACCGGCTTGGTCGAGTAGTAGATGAGTGGCTGCTCGACAAAGGCCGCCAGCTGACCATCTTCAA
CAGCCAGGCTGCCATCAAGATCGGGGGCCGGGATCAGGGCCGCCCCTTCCAGGGCCAGGTGTCCGGCCTCTACTACAATGGGCTCAAGGTGCTGGCGCTG
GCCGCCGAGAGCGACCCCAATGTGCGGACTGAGGGTCACCTGCGCCTGGTGGGGGAGGGGCCGTCCGTGCTGCTCAGTGCGGAGACCACGGCCACCACCC
TGCTGGCTGACATGGCCACCACCATCATGGAGACTACCACCACCATGGCCACTACCACCACGCGCCGGGGCCGCTCCCCCACACTGAGGGACAGCACCAC
CCAGAACACAGATGACCTGCTGGTGGCCTCTGCTGAGTGTCCAAGCGATGATGAGGACCTGGAGGAGTGTGAGCCCAGTACTGGAGGAGAGTTAATATTG
CCCATTATCACGGAGGACTCCTTAGACCCCCCTCCCGTGGCCACCCGATCCCCCTTCGTGCCCCCGCCCCCTACCTTCTACCCCTTCCTCACGGGAGTGG
GCGCCACCCAAGACACGCTGCCCCCGCCCGCCGCGCGCCGCCCGCCCTCTGGGGGCCCGTGCCAGGCCGAGCGGGACGACAGCGACTGCGAGGAGCCCAT
CGAGGCCTCGGGCTTCGCCTCCGGGGAGGTCTTTGACTCCAGCCTCCCCCCCACGGACGACGAGGACTTTTACACCACCTTTCCCCTGGTCACGGACCGC
ACCACCCTCCTGTCACCCCGCAAACCCGCTCCCCGGCCCAACCTCAGGACAGATGGGGCCACGGGCGCCCCTGGGGTGCTGTTTGCCCCCTCCGCCCCGG
CCCCCAACCTGCCGGCGGGCAAAATGAACCACCGAGACCCGCTTCAGCCCTTGCTGGAGAACCCGCCCTTGGGGCCCGGGGCCCCCACGTCCTTTGAGCC
GCGGAGGCCCCCTCCCCTGCGCCCCGGCGTGACCTCAGCCCCCGGCTTCCCCCATCTGCCCACAGCCAACCCCACAGGGCCTGGGGAGCGGGGCCCGCCG
GGCGCAGTGGAGGTGATCCGGGAGTCCAGCAGCACCACGGGCATGGTGGTGGGCATTGTGGCGGCGGCGGCGCTCTGCATCCTCATCCTCCTCTACGCCA
TGTATAAGTACCGCAATCGTGATGAGGGCTCCTACCAGGTGGACCAGAGCCGAAACTACATCAGTAACTCGGCCCAGAGCAATGGGGCGGTGGTGAAAGA
GAAGGCCCCGGCTGCCCCCAAGACGCCCAGCAAGGCCAAGAAGAACAAAGACAAGGAGTATTATGTCTGAGCCCCCGGCACTGCGCCCCACTGCCAGCTG
CCCCTCCTGGGAGGGCCCGGGAGGAGGGTGCCACCCTCTCCCTGCCAGGGGCCTGGGGACCCTCTCCCTGGCTGCCTCAGGCTTCTCTTACGAAGAGGAA
ACGCAAAAAAAGAAAAGGAAAAACCCCGTGCTCGCCCCCTTCCTCCTGCCGTCCACTGCGCGGCCTCGTCAGTCCCGGGGCTGACTGTCCCTCTCAGCTC
TGCGCCTGCCAGGCAGGGCACGTGCTCACAGCCCTGGGTTGATTTATTTTTTTAAGGGGGTAGTTTTATTTTGGTGGGGTTGGGTGGGAAGGAAGGCTGG
GGGTTTTGTAAAGTGTCCACTGCTCGTCCTGTTAATTTTCCTCAATTTTTCTTCTTCTTCCTTCTGTCCCTCCTGCCTTCCTTCTCTTCCCAAGCCCTCC
AATCCCCATCCCAGGCTTGCTGTGTCTCACTGTCCCCACCCTCCTTCCCTACTTCTTTTTTTGTGTGTCTGGTTTCTCCCTTCCTTTCCTCCCTTTGGGT
TTCCAGAGTCGGTGGGAGAAGGGCGGGAGGGTGGGCCCGAGTGGCCCAGTGGGTGGGTGGGGTGGGGTGGGGCAAGTGCCCCAACTCCCCTCACCAGGAG
AGGCACCTGCTTGGTGCCGCCCAGGGAAGGGGCTCAGGCCTGACGGAAGGCCTGTTCTGTGTGTGCCGCCGGGCGACGTGCATTGATGGGGAAGCTGCTG
GAGGAGCAGGGGTGGGGGGTGGGAGGGAGGGGAAAGGCAAATGCAGATATATATTACAGACAAATACTCTAGATTCCACGAGCAGCAGCCTGTGGCACCC
GCTGGGCGCGGGCAGCAGGGAAGAGGGAGCAAGGCATTGTCCACAGACTGCTGGGGTCACTTCTTTGCCCACGGGCTCCCTGCTCCCCCAGTTTTTTTTC
TCTCTTTGTTAACAAATGTGTCTGAGTCTTGGAAAACACCCCAACCCCGGAAATGTGTGGGAAAAAGAAAACAAAAACTTTCCAAATTCCAA
  • refseq_NRXN2.F5 (forward primer)
  • refseq_NRXN2.R5 (reverse primer)
  • Single exon skipping

Frame 0

CRDAAAGAAALTRGASSSERHRGGAGGREAADT
ASPGSATRRRRGGPVALLPTLQLLAPREPGIPPC
SSVGARGGGGAPPPPPEGSRHLGLCAPRPAAGP
MAL*ACKGAPLSAGSARPPPAPCARGSEA*AGA
GGRAGPGPP*AWRPGAGGGRHRRRCCCCCCWRWR
RARTAWSSAAAPGSGLATRAGRARRAAASSASA
CAPTPRARCCSTWTTAATATSWSCCWWTAACGC
ASRFRAPSRPRCSWTRRWPTTAGTWCC*PATRAA
RRWRWTARPAPPRCAPSGARCRWPATCSWAASR
PTCASRRLR*APSSTSRPSAASWPT*SWASGPP
RCWAARACAAPPPTRCARPRATPAPTAASAPCWP
PARWAATAATRASAASSAAKRSTPWKVRLT*R*
TAK*GPYCSPRGGPGEEEPAMCTSQQKARRSLW
RPSKAMSSSATTCHTTPSRAALMRSHWPSAPCNA
TA*CCIQASRPTTSTCPSSLGLSGWSST*AQVP
SRPLWNPSMASSTTTPGTTSGSPETCASTQGLD
TLW*TNCIIW*PSRWTGS*PPQATRRRITPCWAL
MTSSTLGAAPTQLTCRARPSATTSWAASRTWSI
RTMTSNWNYPAWQRKGTPR*SCRGTCHSAVRMW
LPWTL*PLRVPRPLWRCPAGALSALAPSP*TSAP
PSPMGCCSSARAGGLGVELAATALLSGPTTLPW
SYWTATSIFCWTWDLGASSCGHPAARSMMASGV
TWTSRGMGEKAPSQ*IVAARRSWPLETARFWTWR
VSCTWAVSLRGAGWTCPCPQRCGQQHSGQATWA
VCGTSS*MGVAETSGAWLRLRGLWALPPFAPGR
R*SSVHLPPVAMGASVEKAGTASSVTASGPAFLG
GSVRERPRS*ATMAPCT*RSCCLTPCTRRQRMC
PCVSCPSGPTDS*WPPLPGSLPTPYAWSWMGGR
*SSLSTSTACASAAHPVKAPKRCLRGTSSMTMSG
TR*GWSGVARACSCLWTT*LWRDRWQEPICGWS
STTLRRAS*RSGGLSPWCPPTSSGI*VGSCSMA
SPTWTSARMVTSPTVSSMLALACVPSWPIPSPSR
VAAATWHSPRSKPMLPCTSSSSSRPRPLMGFFC
STRATAMTSLSSSWSRGTSTTCLTWGMARP**R
GTQTNQSMTTSGTTWWCPGTQATCTRSRLTPALS
RSTPMAPETSISKGSCTLAV*ARICSATCPSWW
PPGMAFRAAWPQWTSTDVSQTSSPTPCTALGRW
RGAVMAPAPPALKSPVPTRASACSSGMASPATAP
*LPMEALSAMIPGPHTSLGRGERSSPTRGPPMT
GPARGWIAWPWASAPTSGALCWCGWTAPPALET
TCSCTSTRAPWG*SLTWARTTLPSTSPTP**ATA
NTTWCASLEAAATPPCRWTAGRSTSGTRQETLI
TSAWRLLDRESPTGLVE**MSGCSTKAAS*PSS
TARLPSRSGAGIRAAPSRARCPASTTMGSRCWRW
PPRATPMCGLRVTCAWWGRGRPCCSVRRPRPPP
CWLTWPPPSWRLPPPWPLPPRAGAAPPH*GTAP
PRTQMTCWWPLLSVQAMMRTWRSVSPVLEES*YC
PLSRRTP*TPLPWPPDPPSCPRPLPSTPSSREW
APPKTRCPRPPRAARPLGARARPSGTTATARSP
SRPRASPPGRSLTPASPPRTTRTFTPPFPWSRTA
PPSCHPANPLPGPTSGQMGPRAPLGCCLPPPPR
PPTCRRAK*TTETRFSPCWRTRPWGPGPPRPLS
RGGPLPCAPA*PQPPASPICPQPTPQGLGSGARR
AQWR*SGSPAAPRAWWWALWRRRRSASSSSSTP
CISTAIVMRAPTRWTRAETTSVTRPRAMGRW*K
RRPRLPPRRPARPRRTKTRSIMSEPPALRPTASC
PSWEGPGGGCHPLPARGLGTLSLAASGFSYEEE
TQKKKRKNPVLAPFLLPSTARPRQSRG*LSLSA
LRLPGRARAHSPGLIYFFKGVVLFWWGWVGRKAG
GFVKCPLLVLLIFLNFSSSSFCPSCLPSLPKPS
NPHPRLAVSHCPHPPSLLLFLCVWFLPSFPPFG
FPESVGEGREGGPEWPSGWVGWGGASAPTPLTRR
GTCLVPPREGAQA*RKACSVCAAGRRALMGKLL
EEQGWGVGGRGKANADIYYRQIL*IPRAAACGT
RWARAAGKREQGIVHRLLGSLLCPRAPCSPSFFS
LFVNKCV*VLENTPTPEMCGKKKTKTFQIP

Frame 1

AGMRRREQPP*LAEHPPRRGTAAGRAGARRQTP
LALALPPVGDGAAL*LCYPPSSFWRPENQASLP
ALLSEPAAGEGRRRRRLREAGIWASARLAPRPGP
WHCEPAREPRSARGAPGPLPPHAPAALKPERGP
GAGRGRGRRRHGVREPVAADTAAAAVAAAAGAG
GARGRPGVRRRPRAVGSLRALGGRGEQRRAQLQP
AHQRHARAAALPGRRRRLRLPGAAAGGRPPAAA
LHAFVRRAGHAAAGHAGGRRPLAHGAADPRRAP
HGAGGGRRGPRRRGALQAARDAGGQRPVRGRHPA
RRAPLGAYAEHRQVRAALPRPLGQPEAGRAAPR
AAGQPGPARRHRRPAVRARAQPLRQRRPLHRAG
PRRGGLRLQPHGLRRQVLQRRGAPHGRSGSPDVK
QRSRVLTVLRGGGRERRSRRCAPANKRQGGVCG
DLQRQ*VLLLRPVTQPHPEQH**DHTGLPHPAT
QRPDAAYRQVGRLRQPVPQVWGCLAGHQPRLRCL
RGPCGTRQWQVQRQRLARRPGHPKPAPARRDWT
RYGKQTALSGDHLGGRDPDHHRLHAGGLHHAGL
**LLLHWGQPQHS*PAGLARQQQLHGLPQGRGL*
EQ*LQIGTIPPGKGRGPQDEAAGGLVIPL*GCG
CPGPCDL*ESRGLCGAAPLER*AHWLHLPRLPH
HRAQWAAALQPGPAGWGWSWQPQLCSAGRLLCHG
AIGRPPLSSAGHGIWGHQAAGIQPQGQ*WRVVS
RGLPEGWAKRLHLSE*SQHAVLGHWRQRDSGPG
E*AVPGRSP*GGPGGPAPAPRGVDSSTPGRLRGL
CAGPLHRWA*PRPPGPG*GSGGCGRCPLLLPGD
AEAVCICPLSQWGRLSRRLEPLHL*LHRDRLSW
AGL*ERGHGPELRWLHVHEDHAA*RHAHGGRGCV
PAFHVPAGLRTHDGHHFQGVCRHPTPGAGWGAD
EAHCQPRLPARRLRTQ*RPRNAVCGAQAQ*Q*V
AHGEGGPAWQEPAAVCGQRDCGGTDGRSPYAAGV
PQH*DGHHDGAAVYLRGALQLHRASEWARVQWP
ALHGPVQGW*HHLL*AQCSLWPACHRGRSRHLQ
ESQQLPGTRHAPSLCFHAPLLPVQDHGP*WASSV
QLGQRQ*LHCHRAGQGVHPLRV*PGEWPVLDEG
ELRQTSQ*QPVAQRGGVQGPRQRAHAQD*LPHC
HAALQWRPKPRSQRGVVHWRSEQEYVQQPAQAGG
LPGWLSGLPGLSGPQRTSPRPHRRRPAPHWAGG
EGL*WPQHHLH*RVLCQPGRLLAAVGWLHLRLH
HDFLWRPCLQ*SRDHIHLWEGGSAHHLHVAPQ*Q
AQHEDGSPGRGLQHPPAERCAGAGGQRLRPWRL
PAAAHRPGHRGGDL*RGHGRHYHRRAQRHSKRR
QIPRGALHSKRRQRHPAGGQLAGQRAVPGRKL**
RAPGDC*TENPLPAWSSSR*VAARQRPPADHLQ
QPGCHQDRGPGSGPPLPGPGVRPLLQWAQGAGA
GRRERPQCAD*GSPAPGGGGAVRAAQCGDHGHHP
AG*HGHHHHGDYHHHGHYHHAPGPLPHTEGQHH
PEHR*PAGGLC*VSKR**GPGGV*AQYWRRVNI
AHYHGGLLRPPSRGHPIPLRAPAPYLLPLPHGSG
RHPRHAAPARRAPPALWGPVPGRAGRQRLRGAH
RGLGLRLRGGL*LQPPPHGRRGLLHHLSPGHGP
HHPPVTPQTRSPAQPQDRWGHGRPWGAVCPLRPG
PQPAGGQNEPPRPASALAGEPALGARGPHVL*A
AEAPSPAPRRDLSPRLPPSAHSQPHRAWGAGPA
GRSGGDPGVQQHHGHGGGHCGGGGALHPHPPLRH
V*VPQS**GLLPGGPEPKLHQ*LGPEQWGGGER
EGPGCPQDAQQGQEEQRQGVLCLSPRHCAPLPA
APPGRAREEGATLSLPGAWGPSPWLPQASLTKRK
RKKRKGKTPCSPPSSCRPLRGLVSPGADCPSQL
CACQAGHVLTALG*FIFLRG*FYFGGVGWEGRL
GVL*SVHCSSC*FSSIFLLLPSVPPAFLLFPSPP
IPIPGLLCLTVPTLLPYFFFCVSGFSLPFLPLG
FQSRWEKGGRVGPSGPVGGWGGVGQVPQLPSPG
EAPAWCRPGKGLRPDGRPVLCVPPGDVH*WGSCW
RSRGGGWEGGERQMQIYITDKYSRFHEQQPVAP
AGRGQQGRGSKALSTDCWGHFFAHGLPAPPVFF
LSLLTNVSESWKTPQPRKCVGKRKQKLSKFQ

Frame 2

QGCGGGSSRPDSRSILLGEAPRRGGRARGGRHR
*PWLCHPSETGRPCSSATHPPASGAPRTRHPSL
LFCRSPRRGRGAAAAA*GKPASGPLRASPRGRA
HGTVSLQGSPAQRGERPAPSRPMRPRL*SLSGGR
GPGGAGAAVGMASGSRWRPTPPPLLLLLLLALA
ARADGLEFGGGPGQWARYARWAGAASSGELSFS
LRTNATRALLLYLDDGGDCDFLELLLVDGRLRLR
FTLSCAEPATLQLDTPVADDRWHMVLLTRDARR
TALAVDGEARAAEVRSKRREMQVASDLFVGGIP
PDVRLSALTLSTVKYEPPFRGLLANLKLGERPPA
LLGSQGLRGATADPLCAPARNPCANGGLCTVLA
PGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTL
NSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVA
TFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQR
NGLMLHTGKSADYVNLSLKSGAVWLVINLGSGA
FEALVEPVNGKFNDNAWHDVRVTRNLRQHAGIGH
AMVNKLHYLVTISVDGILTTTGYTQEDYTMLGS
DDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVY
KNNDFKLELSRLAKEGDPKMKLQGDLSFRCEDVA
ALDPVTFESPEAFVALPRWSAKRTGSISLDFRT
TEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAM
ELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCH
VDFQRDGRKGSISVNSRSTPFLATGDSEILDLE
SELYLGGLPEGGRVDLPLPPEVWTAALRAGYVG
CVRDLFIDGRSRDLRGLAEAQGAVGVAPFCSRET
LKQCASAPCRNGGVCREGWNRFICDCIGTGFLG
RVCEREATVLSYDGSMYMKIMLPNAMHTEAEDV
SLRFMSQRAYGLMMATTSRESADTLRLELDGGQM
KLTVNLDCLRVGCAPSKGPETLFAGHKLNDNEW
HTVRVVRRGKSLQLSVDNVTVEGQMAGAHMRLE
FHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQ
PYMDQCKDGDITYCELNARFGLRAIVADPVTFK
SRSSYLALATLQAYASMHLFFQFKTTAPDGLLL
FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKG
NSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTV
TQHSNGARNLDLKGELYIGGLSKNMFSNLPKLV
ASRDGFQGCLASVDLNGRLPDLIADALHRIGQVE
RGCDGPSTTCTEESCANQGVCLQQWDGFTCDCT
MTSYGGPVCNDPGTTYIFGKGGALITYTWPPND
RPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDY
LQLHIDQGTVGVIFNVGTDDITIDEPNAIVSDG
KYHVVRFTRSGGNATLQVDSWPVNERYPAGNFD
NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFN
SQAAIKIGGRDQGRPFQGQVSGLYYNGLKVLAL
AAESDPNVRTEGHLRLVGEGPSVLLSAETTATT
LLADMATTIMETTTTMATTTTRRGRSPTLRDSTT
QNTDDLLVASAECPSDDEDLEECEPSTGGELIL
PIITEDSLDPPPVATRSPFVPPPPTFYPFLTGV
GATQDTLPPPAARRPPSGGPCQAERDDSDCEEPI
EASGFASGEVFDSSLPPTDDEDFYTTFPLVTDR
TTLLSPRKPAPRPNLRTDGATGAPGVLFAPSAP
APNLPAGKMNHRDPLQPLLENPPLGPGAPTSFEP
RRPPPLRPGVTSAPGFPHLPTANPTGPGERGPP
GAVEVIRESSSTTGMVVGIVAAAALCILILLYA
MYKYRNRDEGSYQVDQSRNYISNSAQSNGAVVKE
KAPAAPKTPSKAKKNKDKEYYV*APGTAPHCQL
PLLGGPGRRVPPSPCQGPGDPLPGCLRLLLRRG
NAKKEKEKPRARPLPPAVHCAASSVPGLTVPLSS
APARQGTCSQPWVDLFF*GGSFILVGLGGKEGW
GFCKVSTARPVNFPQFFFFFLLSLLPSFSSQAL
QSPSQACCVSLSPPSFPTSFFVCLVSPFLSSLWV
SRVGGRRAGGWARVAQWVGGVGWGKCPNSPHQE
RHLLGAAQGRGSGLTEGLFCVCRRATCIDGEAA
GGAGVGGGREGKGKCRYILQTNTLDSTSSSLWHP
LGAGSREEGARHCPQTAGVTSLPTGSLLPQFFF
SLC*QMCLSLGKHPNPGNVWEKENKNFPNS

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