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Sequences

Sequence CAPN3.mAug05

CCATTCTGTGATATTTATTGAGCACCTACTATGTTCCAGGCACTGTCCTAGGCACTAAGGATAGAGTAGTGAAGTAAACAGAAAGAAATCCCTGCCTTCA
TGGAGCTTAATATTCTAACATGAGACAATAATGGATAGGAAAAACATATGTAGCATGTTAGATTTGGAGAGGTGATATGGAGCAAAAATAAAGTAGGGAA
GAGGGATAGGAGGTGTTGGGGATGCTTGAAATTTTAGGTTAGCATGGCCAGGAAAGCCACATCCTGTCCCTGGCCACCACAGATGAGCTCATAGCCCCTG
CCACTCTGATCTCTGTCCTTGGAAGATGCACCAGGTCCATGGGTAGGTGGCTGGGTCATGCCTTTGGGGGGCTCTGAGCAATACTAACAAGAACCTGCGT
GCCTGGGCTTGGCTGTCGGGGATGGTGCTGACATGGGGCTGGTTCCTGGGGTTGGGGTGTTCCAGGGGTTCTCTAGAGGCTGGTTCTGGCTTGGCTGCCA
GGAAGCCGTGCACCAGAGCAAACCGTCCACGGGCCTCCTGCTTGCTTCTGGTGACACTGAGACCCCACATGTCTGTATTCCTCACAGGGAAGTTGAAAAT
ACCATCTCCGTGGATCGGCCAGTGGTGAGTGGTTTAGATCTTCTGTGCGAAAAGTCCAGAGGGTCCCCTTCCCTGACCATGCAGGGGACAGATGGTGCAG
GGGAGAATGGGCACTGGCAGAGGGAATGGGAGTCTGGGCTGTGCTGAGCAGTCCCTCCTTGGCACTGCAAATCCTACTTTGGCATGGCCAGAAGTAATCG
GCCTTAAGCACCGGGGGCCATTGAGGCAGTTCAGGGGCTGGGAAATATGGAAGAGGGTCCTGGAAAGGAGAAGCAATTTGAACAATCGGAGGGAACAAGG
CCACAGGAAGGGATGACAAGAGCCGCAGCGAACACTGGATTCTGAGACTGGATAACATTGGATTTCACACATAGAGAAAAGAAAGTAAGCTGGTGCCGGA
CCTGGTGTTGACACTTGGATCCTCCACTTACCAGCGGGGTGACCTGGACAATTTCTGTAATCCCTCTCACTCAGTTTCCTACTCAGTAAAACGGGGATGA
TAATGTGCCTTGCAAGGCTTTTGTGAGGCTTCATCAATGAGGTGATGTATGTGAAGTGTCTGGCACAGCATGGGCACTCAAACAGAGGTGCTTTTTCACA
CTTTACACCTTACAAGGTACTTTTCACATGTGTCATCGCGATACTTGCAAGGTTGCTGAGAGGTAGATGGGGTTATAATCCCTGGTGTTCAAGAAAGGAA
GCAGAGGCTCAATGGGGTTGAATGACTTCTCTGAGTTCACAGAGCTCAGTAAGTGGCAGGGTTGGAACTCACATTCAGACTCTCTGACTCCAGACTTAGG
TTTTTCCGCACCTCCACGCTGAGGCCAGCCCCAGGCAGTGAGAAGCCCAAAGTCCGAAGCACAGAGTGCTGTGTGTTGGGCTCTGTGTGTTGAGGAGTCT
TGTGACTGCCTTGGGGCTTTGGGCTGTAGTCAGCTGACAGTCCTTTGTGCTCTGTGGGGATGACGTAGGCCAATGGGAGGACAAATGCCCCTCTGAACTG
TCTTCTGGGCAGTGACAGTCATGGTCATAATCCTGACCCTGAGCCAGTGCCAGGTCTCCAAGTGCCTTCTGAATGACCACAGGCGATTGGTTTTAGTGGT
AGGTGTGTGGGGATCTGTTCTGGTCATCTGGATGCTGGTCATCGGTGTGCAGTATTGATCAGGACCTGCAAACCCAAAAGCTTATGGGAGCTGGCACGTC
ACCCCATCATCTTCGTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAAGCCCTGATAAGCA
AAAGCAGTCCCCACAGCCACAGCCTGGCAGCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAGATAGCAGGAGATGACATG
GAGATCTGTGCAGATGAGCTCAAGAAGGTCCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACACTGGAGTCCTGCCGTAGCA
TGATTGCGCTCATGGATACAGATGGCTCTGGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTGGCAGAAAATTTTCAAACA
CTATGACACAGACCAGTCCGGCACCATCAACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAACCAGCTCTATGACATCATT
ACCATGCGGTACGCAGACAAACACATGAACATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCAGAGCTTTTCATGCATTTG
ACAAGGATGGAGATGGTATCATCAAGCTCAACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTCATCCAAAGCCATGCAGGA
TCACTCAGGATTTCAGTTTCACCCTCTATTTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCCAGGCACCTCATCAGTCAT
GCTCCTCCTCCATTTTACCCCCTACCCATCCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAGAACAAACCCTTGTCCCTT
TGCCATGTGGAGGAAAGTGCCTGCCTCTGGTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGCTGTCTGCAGAAGCACCTG
CCGGTGGCACTCAGCACCTCCTTGTGCTAGAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGCACTGGGTTCTACTGCTGT
GGGGTAAACTAACTCAGTGGAATAGGGCTGGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTGATCTAAATAAAGGCATGT
GTATGGCTGGTC
  • CAPN3.u.f.52 (forward primer)
  • CAPN3.u.r.55 (reverse primer)
  • Single exon skipping

Frame 0

PFCDIY*APTMFQALS*ALRIE**SKQKEIPAF
MELNILT*DNNG*EKHM*HVRFGEVIWSKNKVGK
RDRRCWGCLKF*VSMARKATSCPWPPQMSS*PL
PL*SLSLEDAPGPWVGGWVMPLGGSEQY*QEPA
CLGLAVGDGADMGLVPGVGVFQGFSRGWFWLGCQ
EAVHQSKPSTGLLLASGDTETPHVCIPHREVEN
TISVDRPVVSGLDLLCEKSRGSPSLTMQGTDGA
GENGHWQREWESGLC*AVPPWHCKSYFGMARSNR
P*APGAIEAVQGLGNMEEGPGKEKQFEQSEGTR
PQEGMTRAAANTGF*DWITLDFTHREKKVSWCR
TWC*HLDPPLTSGVTWTISVIPLTQFPTQ*NGDD
NVPCKAFVRLHQ*GDVCEVSGTAWALKQRCFFT
LYTLQGTFHMCHRDTCKVAER*MGL*SLVFKKG
SRGSMGLNDFSEFTELSKWQGWNSHSDSLTPDLG
FSAPPR*GQPQAVRSPKSEAQSAVCWALCVEES
CDCLGALGCSQLTVLCALWG*RRPMGGQMPL*T
VFWAVTVMVIILTLSQCQVSKCLLNDHRRLVLVV
GVWGSVLVIWMLVIGVQY*SGPANPKAYGSWHV
TPSSSFRTEQTATRSWVWTRSQRRAKAKQALIS
KSSPHSHSLAALIRKVRNSNNSGTFSSR*QEMTW
RSVQMSSRRSLTQS*TNTRT*RHTGSHWSPAVA
*LRSWIQMALESSTCRSSTTSGTRLRPGRKFSN
TMTQTSPAPSTATRCEMQSTTQDSTSTTSSMTSL
PCGTQTNT*TSTLTVSSAASLGWRACSELFMHL
TRMEMVSSSSTFWSGCSSPCMPEPGWPHPKPCR
ITQDFSFTLYFQSHLPQRTQQLHPYRLPGTSSVM
LLLHFTPYPSLIGHA*PDPLVKQ*GRKNKPLSL
CHVEESACLWSEPPRF*SECSCLPCSRLSAEAP
AGGTQHLLVLEPSITFTLSHHGPGTKPALGSTAV
G*TNSVE*GWLLWAVQLISLAAF*KKLI*IKAC
VWLV

Frame 1

HSVIFIEHLLCSRHCPRH*G*SSEVNRKKSLPS
WSLIF*HETIMDRKNICSMLDLER*YGAKIK*G
RGIGGVGDA*NFRLAWPGKPHPVPGHHR*AHSPC
HSDLCPWKMHQVHG*VAGSCLWGALSNTNKNLR
AWAWLSGMVLTWGWFLGLGCSRGSLEAGSGLAA
RKPCTRANRPRASCLLLVTLRPHMSVFLTGKLKI
PSPWIGQW*VV*IFCAKSPEGPLP*PCRGQMVQ
GRMGTGRGNGSLGCAEQSLLGTANPTLAWPEVI
GLKHRGPLRQFRGWEIWKRVLERRSNLNNRREQG
HRKG*QEPQRTLDSETG*HWISHIEKRK*AGAG
PGVDTWILHLPAG*PGQFL*SLSLSFLLSKTGM
IMCLARLL*GFINEVMYVKCLAQHGHSNRGAFSH
FTPYKVLFTCVIAILARLLRGRWGYNPWCSRKE
AEAQWG*MTSLSSQSSVSGRVGTHIQTL*LQT*
VFPHLHAEASPRQ*EAQSPKHRVLCVGLCVLRSL
VTALGLWAVVS*QSFVLCGDDVGQWEDKCPSEL
SSGQ*QSWS*S*P*ASARSPSAF*MTTGDWF*W
*VCGDLFWSSGCWSSVCSIDQDLQTQKLMGAGTS
PHHLRFGQSKQQQGAGCGPGVRGGQRQNKP**A
KAVPTATAWQL*SGK*GTATIPEHFQADSRR*H
GDLCR*AQEGP*HSREQTQGPEDTRVHTGVLP*H
DCAHGYRWLWKAQPAGVPPPLEQD*GLAENFQT
L*HRPVRHHQQLRDAKCSQRRRIPPQQPAL*HH
YHAVRRQTHEHRL*QFHLLLR*AGGHVQSFSCI*
QGWRWYHQAQRSGVAAAHHVCLNQAGLIQSHAG
SLRISVSPSISKAIYLKGPSSYTPTGFQAPHQS
CSSSILPPTHP*SVMPSLTL**SNEVGRTNPCPF
AMWRKVPASGPSRLGSEASAPAYLALGCLQKHL
PVALSTSLC*SPPSPSRCPTMGQEPNQHWVLLL
WGKLTQWNRAGYFGLSNS*VWLHFEKS*SK*RHV
YGW

Frame 2

IL*YLLSTYYVPGTVLGTKDRVVK*TERNPCLH
GA*YSNMRQ*WIGKTYVAC*IWRGDMEQK*SRE
EG*EVLGMLEILG*HGQESHILSLATTDELIAP
ATLISVLGRCTRSMGRWLGHAFGGL*AILTRTCV
PGLGCRGWC*HGAGSWGWGVPGVL*RLVLAWLP
GSRAPEQTVHGPPACFW*H*DPTCLYSSQGS*K
YHLRGSASGEWFRSSVRKVQRVPFPDHAGDRWCR
GEWALAEGMGVWAVLSSPSLALQILLWHGQK*S
ALSTGGH*GSSGAGKYGRGSWKGEAI*TIGGNK
ATGRDDKSRSEHWILRLDNIGFHT*RKESKLVPD
LVLTLGSSTYQRGDLDNFCNPSHSVSYSVKRG*
*CALQGFCEASSMR*CM*SVWHSMGTQTEVLFH
TLHLTRYFSHVSSRYLQGC*EVDGVIIPGVQERK
QRLNGVE*LL*VHRAQ*VAGLELTFRLSDSRLR
FFRTSTLRPAPGSEKPKVRSTECCVLGSVC*GV
L*LPWGFGL*SADSPLCSVGMT*ANGRTNAPLNC
LLGSDSHGHNPDPEPVPGLQVPSE*PQAIGFSG
RCVGICSGHLDAGHRCAVLIRTCKPKSLWELAR
HPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQ
KQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDM
EICADELKKVLNTVVNKHKDLKTHGFTLESCRS
MIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKH
YDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII
TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAF
DKDGDGIIKLNVLEWLQLTMYA*TRLASSKAMQD
HSGFQFHPLFPKPFTSKDPAATPLQASRHLISH
APPPFYPLPILDRSCLA*PFSKAMR*EEQTLVP
LPCGGKCLPLVRAASVLKRVLLLTLL*AVCRSTC
RWHSAPPCARALHHLHAVPPWARNQTSTGFYCC
GVN*LSGIGLVTLGCPTHKFGCILKKADLNKGM
CMAG

Sequence CAPN3.lAug05

CCATTCTGTGATATTTATTGAGCACCTACTATGTTCCAGGCACTGTCCTAGGCACTAAGGATAGAGTAGTGAAGTAAACAGAAAGAAATCCCTGCCTTCA
TGGAGCTTAATATTCTAACATGAGACAATAATGGATAGGAAAAACATATGTAGCATGTTAGATTTGGAGAGGTGATATGGAGCAAAAATAAAGTAGGGAA
GAGGGATAGGAGGTGTTGGGGATGCTTGAAATTTTAGGTTAGCATGGCCAGGAAAGCCACATCCTGTCCCTGGCCACCACAGATGAGCTCATAGCCCCTG
CCACTCTGATCTCTGTCCTTGGAAGATGCACCAGGTCCATGGGTAGGTGGCTGGGTCATGCCTTTGGGGGGCTCTGAGCAATACTAACAAGAACCTGCGT
GCCTGGGCTTGGCTGTCGGGGATGGTGCTGACATGGGGCTGGTTCCTGGGGTTGGGGTGTTCCAGGGGTTCTCTAGAGGCTGGTTCTGGCTTGGCTGCCA
GGAAGCCGTGCACCAGAGCAAACCGTCCACGGGCCTCCTGCTTGCTTCTGGTGACACTGAGACCCCACATGTCTGTATTCCTCACAGGGAAGTTGAAAAT
ACCATCTCCGTGGATCGGCCAGTGGTGAGTGGTTTAGATCTTCTGTGCGAAAAGTCCAGAGGGTCCCCTTCCCTGACCATGCAGGGGACAGATGGTGCAG
GGGAGAATGGGCACTGGCAGAGGGAATGGGAGTCTGGGCTGTGCTGAGCAGTCCCTCCTTGGCACTGCAAATCCTACTTTGGCATGGCCAGAAGTAATCG
GCCTTAAGCACCGGGGGCCATTGAGGCAGTTCAGGGGCTGGGAAATATGGAAGAGGGTCCTGGAAAGGAGAAGCAATTTGAACAATCGGAGGGAACAAGG
CCACAGGAAGGGATGACAAGAGCCGCAGCGAACACTGGATTCTGAGACTGGATAACATTGGATTTCACACATAGAGAAAAGAAAGTAAGCTGGTGCCGGA
CCTGGTGTTGACACTTGGATCCTCCACTTACCAGCGGGGTGACCTGGACAATTTCTGTAATCCCTCTCACTCAGTTTCCTACTCAGTAAAACGGGGATGA
TAATGTGCCTTGCAAGGCTTTTGTGAGGCTTCATCAATGAGGTGATGTATGTGAAGTGTCTGGCACAGCATGGGCACTCAAACAGAGGTGCTTTTTCACA
CTTTACACCTTACAAGGTACTTTTCACATGTGTCATCGCGATACTTGCAAGGTTGCTGAGAGGTAGATGGGGTTATAATCCCTGGTGTTCAAGAAAGGAA
GCAGAGGCTCAATGGGGTTGAATGACTTCTCTGAGTTCACAGAGCTCAGTAAGTGGCAGGGTTGGAACTCACATTCAGACTCTCTGACTCCAGACTTAGG
TTTTTCCGCACCTCCACGCTGAGGCCAGCCCCAGGCAGTGAGAAGCCCAAAGTCCGAAGCACAGAGTGCTGTGTGTTGGGCTCTGTGTGTTGAGGAGTCT
TGTGACTGCCTTGGGGCTTTGGGCTGTAGTCAGCTGACAGTCCTTTGTGCTCTGTGGGGATGACGTAGGCCAATGGGAGGACAAATGCCCCTCTGAACTG
TCTTCTGGGCAGTGACAGTCATGGTCATAATCCTGACCCTGAGCCAGTGCCAGGTCTCCAAGTGCCTTCTGAATGACCACAGGCGATTGGTTTTAGTGGT
AGGTGTGTGGGGATCTGTTCTGGTCATCTGGATGCTGGTCATCGGTGTGCAGTATTGATCAGGACCTGCAAACCCAAAAGCTTATGGGAGCTGGCACGTC
ACAAAAAGAAAAAAACCAAGCCCATCATCTTCGTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAA
AACAAGCCCTGATAAGCAAAAGCAGTCCCCACAGCCACAGCCTGGCAGCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAG
ATAGCAGGAGATGACATGGAGATCTGTGCAGATGAGCTCAAGAAGGTCCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACAC
TGGAGTCCTGCCGTAGCATGATTGCGCTCATGGATACAGATGGCTCTGGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTG
GCAGAAAATTTTCAAACACTATGACACAGACCAGTCCGGCACCATCAACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAAC
CAGCTCTATGACATCATTACCATGCGGTACGCAGACAAACACATGAACATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCA
GAGCTTTTCATGCATTTGACAAGGATGGAGATGGTATCATCAAGCTCAACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTC
ATCCAAAGCCATGCAGGATCACTCAGGATTTCAGTTTCACCCTCTATTTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCC
AGGCACCTCATCAGTCATGCTCCTCCTCCATTTTACCCCCTACCCATCCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAG
AACAAACCCTTGTCCCTTTGCCATGTGGAGGAAAGTGCCTGCCTCTGGTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGC
TGTCTGCAGAAGCACCTGCCGGTGGCACTCAGCACCTCCTTGTGCTAGAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGC
ACTGGGTTCTACTGCTGTGGGGTAAACTAACTCAGTGGAATAGGGCTGGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTG
ATCTAAATAAAGGCATGTGTATGGCTGGTC
  • CAPN3.u.f.52 (forward primer)
  • CAPN3.u.r.55 (reverse primer)
  • Single exon skipping

Frame 0

PFCDIY*APTMFQALS*ALRIE**SKQKEIPAF
MELNILT*DNNG*EKHM*HVRFGEVIWSKNKVGK
RDRRCWGCLKF*VSMARKATSCPWPPQMSS*PL
PL*SLSLEDAPGPWVGGWVMPLGGSEQY*QEPA
CLGLAVGDGADMGLVPGVGVFQGFSRGWFWLGCQ
EAVHQSKPSTGLLLASGDTETPHVCIPHREVEN
TISVDRPVVSGLDLLCEKSRGSPSLTMQGTDGA
GENGHWQREWESGLC*AVPPWHCKSYFGMARSNR
P*APGAIEAVQGLGNMEEGPGKEKQFEQSEGTR
PQEGMTRAAANTGF*DWITLDFTHREKKVSWCR
TWC*HLDPPLTSGVTWTISVIPLTQFPTQ*NGDD
NVPCKAFVRLHQ*GDVCEVSGTAWALKQRCFFT
LYTLQGTFHMCHRDTCKVAER*MGL*SLVFKKG
SRGSMGLNDFSEFTELSKWQGWNSHSDSLTPDLG
FSAPPR*GQPQAVRSPKSEAQSAVCWALCVEES
CDCLGALGCSQLTVLCALWG*RRPMGGQMPL*T
VFWAVTVMVIILTLSQCQVSKCLLNDHRRLVLVV
GVWGSVLVIWMLVIGVQY*SGPANPKAYGSWHV
TKRKKPSPSSSFRTEQTATRSWVWTRSQRRAKA
KQALISKSSPHSHSLAALIRKVRNSNNSGTFSSR
*QEMTWRSVQMSSRRSLTQS*TNTRT*RHTGSH
WSPAVA*LRSWIQMALESSTCRSSTTSGTRLRP
GRKFSNTMTQTSPAPSTATRCEMQSTTQDSTSTT
SSMTSLPCGTQTNT*TSTLTVSSAASLGWRACS
ELFMHLTRMEMVSSSSTFWSGCSSPCMPEPGWP
HPKPCRITQDFSFTLYFQSHLPQRTQQLHPYRLP
GTSSVMLLLHFTPYPSLIGHA*PDPLVKQ*GRK
NKPLSLCHVEESACLWSEPPRF*SECSCLPCSR
LSAEAPAGGTQHLLVLEPSITFTLSHHGPGTKPA
LGSTAVG*TNSVE*GWLLWAVQLISLAAF*KKL
I*IKACVWLV

Frame 1

HSVIFIEHLLCSRHCPRH*G*SSEVNRKKSLPS
WSLIF*HETIMDRKNICSMLDLER*YGAKIK*G
RGIGGVGDA*NFRLAWPGKPHPVPGHHR*AHSPC
HSDLCPWKMHQVHG*VAGSCLWGALSNTNKNLR
AWAWLSGMVLTWGWFLGLGCSRGSLEAGSGLAA
RKPCTRANRPRASCLLLVTLRPHMSVFLTGKLKI
PSPWIGQW*VV*IFCAKSPEGPLP*PCRGQMVQ
GRMGTGRGNGSLGCAEQSLLGTANPTLAWPEVI
GLKHRGPLRQFRGWEIWKRVLERRSNLNNRREQG
HRKG*QEPQRTLDSETG*HWISHIEKRK*AGAG
PGVDTWILHLPAG*PGQFL*SLSLSFLLSKTGM
IMCLARLL*GFINEVMYVKCLAQHGHSNRGAFSH
FTPYKVLFTCVIAILARLLRGRWGYNPWCSRKE
AEAQWG*MTSLSSQSSVSGRVGTHIQTL*LQT*
VFPHLHAEASPRQ*EAQSPKHRVLCVGLCVLRSL
VTALGLWAVVS*QSFVLCGDDVGQWEDKCPSEL
SSGQ*QSWS*S*P*ASARSPSAF*MTTGDWF*W
*VCGDLFWSSGCWSSVCSIDQDLQTQKLMGAGTS
QKEKNQAHHLRFGQSKQQQGAGCGPGVRGGQRQ
NKP**AKAVPTATAWQL*SGK*GTATIPEHFQA
DSRR*HGDLCR*AQEGP*HSREQTQGPEDTRVHT
GVLP*HDCAHGYRWLWKAQPAGVPPPLEQD*GL
AENFQTL*HRPVRHHQQLRDAKCSQRRRIPPQQ
PAL*HHYHAVRRQTHEHRL*QFHLLLR*AGGHVQ
SFSCI*QGWRWYHQAQRSGVAAAHHVCLNQAGL
IQSHAGSLRISVSPSISKAIYLKGPSSYTPTGF
QAPHQSCSSSILPPTHP*SVMPSLTL**SNEVGR
TNPCPFAMWRKVPASGPSRLGSEASAPAYLALG
CLQKHLPVALSTSLC*SPPSPSRCPTMGQEPNQ
HWVLLLWGKLTQWNRAGYFGLSNS*VWLHFEKS*
SK*RHVYGW

Frame 2

IL*YLLSTYYVPGTVLGTKDRVVK*TERNPCLH
GA*YSNMRQ*WIGKTYVAC*IWRGDMEQK*SRE
EG*EVLGMLEILG*HGQESHILSLATTDELIAP
ATLISVLGRCTRSMGRWLGHAFGGL*AILTRTCV
PGLGCRGWC*HGAGSWGWGVPGVL*RLVLAWLP
GSRAPEQTVHGPPACFW*H*DPTCLYSSQGS*K
YHLRGSASGEWFRSSVRKVQRVPFPDHAGDRWCR
GEWALAEGMGVWAVLSSPSLALQILLWHGQK*S
ALSTGGH*GSSGAGKYGRGSWKGEAI*TIGGNK
ATGRDDKSRSEHWILRLDNIGFHT*RKESKLVPD
LVLTLGSSTYQRGDLDNFCNPSHSVSYSVKRG*
*CALQGFCEASSMR*CM*SVWHSMGTQTEVLFH
TLHLTRYFSHVSSRYLQGC*EVDGVIIPGVQERK
QRLNGVE*LL*VHRAQ*VAGLELTFRLSDSRLR
FFRTSTLRPAPGSEKPKVRSTECCVLGSVC*GV
L*LPWGFGL*SADSPLCSVGMT*ANGRTNAPLNC
LLGSDSHGHNPDPEPVPGLQVPSE*PQAIGFSG
RCVGICSGHLDAGHRCAVLIRTCKPKSLWELAR
HKKKKTKPIIFVSDRANSNKELGVDQESEEGKGK
TSPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQ
IAGDDMEICADELKKVLNTVVNKHKDLKTHGFT
LESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAW
QKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN
QLYDIITMRYADKHMNIDFDSFICCFVRLEGMF
RAFHAFDKDGDGIIKLNVLEWLQLTMYA*TRLAS
SKAMQDHSGFQFHPLFPKPFTSKDPAATPLQAS
RHLISHAPPPFYPLPILDRSCLA*PFSKAMR*E
EQTLVPLPCGGKCLPLVRAASVLKRVLLLTLL*A
VCRSTCRWHSAPPCARALHHLHAVPPWARNQTS
TGFYCCGVN*LSGIGLVTLGCPTHKFGCILKKA
DLNKGMCMAG

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