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Sequences

Sequence CAPN3.hAug05

CTATTCCAGTGTTTCAGCGAGGTGGAAGTGTGATACCAATAAAGACAACTGTAGGAAAATCCACAGGCTGGATGACTGAATCCTCCTATGGACTCCGGGT TGCTCTAAGCACTAAGGGTTCTTCAGTGGGTGAGTTATATCTTGATGATGGCCATTCATTCCAATACCTCCACCAGAAGCAATTTTTGCACAGGAAGTTT TCATTCTGTTCCAGTGTTCTGATCAATAGTTTTGCTGACCAGAGGGGTCATTATCCCAGCAAGTGTGTGGTGGAGAAGATCTTGGTCTTAGGCTTCAGGA AGGAGCCATCTTCTGTGACTACCCACTCATCTGATGGTAAAGATCAGCCTGTGGCTTTTACGTATTGTGCCAAAACATCCATCCTGAGCCTGGAGAAGCT CTCACTCAACATTGCCACTGACTGGGAGGGTTCCTAAAAAAGCTCTAAAATGAATGCATAGTGTGTCTTTCCTTCAAGATGTAAATGTCAAGGAATGAGT TGGCAAATCAGTTTAAAAACACAAACTACCCAACAGAAAAATGAAATTTGCGAGAATCCCCGATTTATCATTGATGGAGCCAACAGAACTGACATCTGTC AAGGAGAGCTAGGGGACTGCTGGTTTCTCGCAGCCATTGCCTGCCTGACCCTGAACCAGCACCTTCTTTTCCGAGTCATACCCCATGATCAAAGTTTCAT CGAAAACTACGCAGGGATCTTCCACTTCCAGTTCTGGCGCTATGGAGAGTGGGTGGACGTGGTTATAGATGACTGCCTGCCAACGTACAACAATCAACTG GTTTTCACCAAGTCCAACCACCGCAATGAGTTCTGGAGTGCTCTGCTGGAGAAGGCTTATGCTAAGCTCCATGGTTCCTACGAAGCTCTGAAAGGTGGGA ACACCACAGAGGCCATGGAGGACTTCACAGGAGGGGTGGCAGAGTTTTTTGAGATCAGGGATGCTCCTAGTGACATGTACAAGATCATGAAGAAAGCCAT CGAGAGAGGCTCCCTCATGGGCTGCTCCATTGATGATGGCACGAACATGACCTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAGTTGATTGCACGG ATGGTAAGGAATATGGATAACTCACTGCTCCAGGACTCAGACCTCGACCCCAGAGGCTCAGATGAAAGACCGACCCGGACAATCATTCCGGTTCAGTATG AGACAAGAATGGCCTGCGGGCTGGTCAGAGGTCACGCCTACTCTGTCACGGGGCTGGATGAGGTCCCGTTCAAAGGTGAGAAAGTGAAGCTGGTGCGGCT GCGGAATCCGTGGGGCCAGGTGGAGTGGAACGGTTCTTGGAGTGATAGATGGAAGGACTGGAGCTTTGTGGACAAAGATGAGAAGGCCCGTCTGCAGCAC CAGGTCACTGAGGATGGAGAGTTCTGGATGTCCTATGAGGATTTCATCTACCATTTCACAAAGTTGGAGATCTGCAACCTCACGGCCGATGCTCTGCAGT CTGACAAGCTTCAGACCTGGACAGTGTCTGTGAACGAGGGCCGCTGGGTACGGGGTTGCTCTGCCGGAGGCTGCCGCAACTTCCCAGATACTTTCTGGAC CAACCCTCAGTACCGTCTGAAGCTCCTGGAGGAGGACGATGACCCTGATGACTCGGAGGTGATTTGCAGCTTCCTGGTGGCCCTGATGCAGAAGAACCGG CGGAAGGACCGGAAGCTAGGGGCCAGTCTCTTCACCATTGGCTTCGCCATCTACGAGGTTCCCAAAGAGGTATAGCAGCAGCAGCGGCCAGCAGTTGTGT GCAGCACTACCCAGGGGGCCCCGAGTCTGTCTGTGGCTCGTCGAGAAGCTTCCTGGTGGGGTTTGTGGGCAGGACTGTGATAGGAGAGGGCCTTGCCTGT GTTATTTCCACTGCAGAGCAGGTGCCTCAGGGCATTGCATGACCCATGACTACCACCCCCAGGATGTGCACTTTCTCCCTCGCACCAGACACTGCACGTC ACACACATGCCTTTGCACACTCACCCTCCTCCACGCTTACAGCCACACACACAGTCACACAGACGCGTTCTGAGGGTGGCTGCCCGCTTGGGATGGAGGA ATCACTTCCCTCAGAACCCAGCCAAGTCCTCTAGGCCTCCTTGGGGGTCCTTCCAGCCTGAGGGGCTTCGGAGCTGAGGAGCAGCTGTTCTGGTAAGTGT CCCTGAGTGTGGGGATGACACATTTGCCATTCACTCTGAATCACAACAGAAAAGGAAGAGGAAGTGAGGTAGGGAGGCTATTTAAGCCTTGGGAGTCGGA AGTAGGGAGGTTGAAACTGTGACATGGGTGACCAGGGAGTTGGGAAGGGACCCTTGGAGGTGGCTGTGGCAGGACAGGATGTTCCTCCCGAGGGGCTCAT GTGCCCTGGGCTCTCCCCATCTCTCAGATGCACGGGAACAAGCAGCACCTGCAGAAGGACTTCTTCCTGTACAACGCCTCCAAGGCCAGGAGCAAAACCT ACATCAACATGCGGGAGGTGTCCCAGCGCTTCCGCCTGCCTCCCAGCGAGTACGTCATCGTGCCCTCCACCTACGAGCCCCACCAGGAGGGGGAATTCAT CCTCCGGGTCTTCTCTGAAAAGAGGAACCTCTCTGAGGAAGTTGAAAATACCATCTCCGTGGATCGGCCAGTGCCCATCATCTTCGTTTCGGACAGAGCA AACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAAGCCCTGATAAGCAAAAGCAGTCCCCACAGCCACAGCCTGGCA GCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAGATAGCAGGAGATGACATGGAGATCTGTGCAGATGAGCTCAAGAAGGT CCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACACTGGAGTCCTGCCGTAGCATGATTGCGCTCATGGATACAGATGGCTCT GGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTGGCAGAAAATTTTCAAACACTATGACACAGACCAGTCCGGCACCATCA ACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAACCAGCTCTATGACATCATTACCATGCGGTACGCAGACAAACACATGAA CATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCAGAGCTTTTCATGCATTTGACAAGGATGGAGATGGTATCATCAAGCTC AACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTCATCCAAAGCCATGCAGGATCACTCAGGATTTCAGTTTCACCCTCTAT TTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCCAGGCACCTCATCAGTCATGCTCCTCCTCCATTTTACCCCCTACCCAT CCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAGAACAAACCCTTGTCCCTTTGCCATGTGGAGGAAAGTGCCTGCCTCTG GTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGCTGTCTGCAGAAGCACCTGCCGGTGGCACTCAGCACCTCCTTGTGCTA GAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGCACTGGGTTCTACTGCTGTGGGGTAAACTAACTCAGTGGAATAGGGCT GGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTGATCTAAATAAAGGCATGTGTATGGCTGGTC

CAPN3.u.f.52 (forward primer)
CAPN3.u.r.55 (reverse primer)
Alternative donor

Frame 0

LFQCFSEVEV*YQ*RQL*ENPQAG*LNPPMDSG LL*ALRVLQWVSYILMMAIHSNTSTRSNFCTGSF HSVPVF*SIVLLTRGVIIPASVWWRRSWS*ASG RSHLL*LPTHLMVKISLWLLRIVPKHPS*AWRS SHSTLPLTGRVPKKALK*MHSVSFLQDVNVKE*V GKSV*KHKLPNRKMKFARIPDLSLMEPTELTSV KES*GTAGFSQPLPA*P*TSTFFSESYPMIKVS SKTTQGSSTSSSGAMESGWTWL*MTACQRTTINW FSPSPTTAMSSGVLCWRRLMLSSMVPTKL*KVG TPQRPWRTSQEGWQSFLRSGMLLVTCTRS*RKP SREAPSWAAPLMMART*PMEPLLLV*TWGS*LHG W*GIWITHCSRTQTSTPEAQMKDRPGQSFRFSM RQEWPAGWSEVTPTLSRGWMRSRSKVRK*SWCG CGIRGARWSGTVLGVIDGRTGALWTKMRRPVCST RSLRMESSGCPMRISSTISQSWRSATSRPMLCS LTSFRPGQCL*TRAAGYGVALPEAAATSQILSG PTLSTV*SSWRRTMTLMTRR*FAASWWP*CRRTG GRTGS*GPVSSPLASPSTRFPKRYSSSSGQQLC AALPRGPRVCLWLVEKLPGGVCGQDCDRRGPCL CYFHCRAGASGHCMTHDYHPQDVHFLPRTRHCTS HTCLCTLTLLHAYSHTHSHTDAF*GWLPAWDGG ITSLRTQPSPLGLLGGPSSLRGFGAEEQLFW*V SLSVGMTHLPFTLNHNRKGRGSEVGRLFKPWESE VGRLKL*HG*PGSWEGTLGGGCGRTGCSSRGAH VPWALPISQMHGNKQHLQKDFFLYNASKARSKT YINMREVSQRFRLPPSEYVIVPSTYEPHQEGEFI LRVFSEKRNLSEEVENTISVDRPVPIIFVSDRA NSNKELGVDQESEEGKGKTSPDKQKQSPQPQPG SSDQESEEQQQFRNIFKQIAGDDMEICADELKKV LNTVVNKHKDLKTHGFTLESCRSMIALMDTDGS GKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTI NSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMN IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL NVLEWLQLTMYA*TRLASSKAMQDHSGFQFHPL FPKPFTSKDPAATPLQASRHLISHAPPPFYPLPI LDRSCLA*PFSKAMR*EEQTLVPLPCGGKCLPL VRAASVLKRVLLLTLL*AVCRSTCRWHSAPPCA RALHHLHAVPPWARNQTSTGFYCCGVN*LSGIGL VTLGCPTHKFGCILKKADLNKGMCMAG

Frame 1

YSSVSARWKCDTNKDNCRKIHRLDD*ILLWTPG CSKH*GFFSG*VIS**WPFIPIPPPEAIFAQEV FILFQCSDQ*FC*PEGSLSQQVCGGEDLGLRLQE GAIFCDYPLI*W*RSACGFYVLCQNIHPEPGEA LTQHCH*LGGFLKKL*NECIVCLSFKM*MSRNE LANQFKNTNYPTEK*NLRESPIYH*WSQQN*HLS RRARGLLVSRSHCLPDPEPAPSFPSHTP*SKFH RKLRRDLPLPVLALWRVGGRGYR*LPANVQQST GFHQVQPPQ*VLECSAGEGLC*APWFLRSSERWE HHRGHGGLHRRGGRVF*DQGCS**HVQDHEESH RERLPHGLLH**WHEHDLWNLSFWSEHGGVDCT DGKEYG*LTAPGLRPRPQRLR*KTDPDNHSGSV* DKNGLRAGQRSRLLCHGAG*GPVQR*ESEAGAA AESVGPGGVERFLE**MEGLELCGQR*EGPSAA PGH*GWRVLDVL*GFHLPFHKVGDLQPHGRCSAV *QASDLDSVCERGPLGTGLLCRRLPQLPRYFLD QPSVPSEAPGGGR*P**LGGDLQLPGGPDAEEP AEGPEARGQSLHHWLRHLRGSQRGIAAAAASSCV QHYPGGPESVCGSSRSFLVGFVGRTVIGEGLAC VISTAEQVPQGIA*PMTTTPRMCTFSLAPDTAR HTHAFAHSPSSTLTATHTVTQTRSEGGCPLGMEE SLPSEPSQVL*ASLGVLPA*GASELRSSCSGKC P*VWG*HICHSL*ITTEKEEEVR*GGYLSLGSR K*GG*NCDMGDQGVGKGPLEVAVAGQDVPPEGLM CPGLSPSLRCTGTSSTCRRTSSCTTPPRPGAKP TSTCGRCPSASACLPASTSSCPPPTSPTRRGNS SSGSSLKRGTSLRKLKIPSPWIGQCPSSSFRTEQ TATRSWVWTRSQRRAKAKQALISKSSPHSHSLA ALIRKVRNSNNSGTFSSR*QEMTWRSVQMSSRR SLTQS*TNTRT*RHTGSHWSPAVA*LRSWIQMAL ESSTCRSSTTSGTRLRPGRKFSNTMTQTSPAPS TATRCEMQSTTQDSTSTTSSMTSLPCGTQTNT* TSTLTVSSAASLGWRACSELFMHLTRMEMVSSSS TFWSGCSSPCMPEPGWPHPKPCRITQDFSFTLY FQSHLPQRTQQLHPYRLPGTSSVMLLLHFTPYP SLIGHA*PDPLVKQ*GRKNKPLSLCHVEESACLW SEPPRF*SECSCLPCSRLSAEAPAGGTQHLLVL EPSITFTLSHHGPGTKPALGSTAVG*TNSVE*G WLLWAVQLISLAAF*KKLI*IKACVWLV

Frame 2

IPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRV ALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKF SFCSSVLINSFADQRGHYPSKCVVEKILVLGFR KEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKL SLNIATDWEGS*KSSKMNA*CVFPSRCKCQGMS WQISLKTQTTQQKNEICENPRFIIDGANRTDIC QGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFI ENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQL VFTKSNHRNEFWSALLEKAYAKLHGSYEALKGG NTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAI ERGSLMGCSIDDGTNMTYGTSPSGLNMGELIAR MVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQY ETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRL RNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQH QVTEDGEFWMSYEDFIYHFTKLEICNLTADALQ SDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWT NPQYRLKLLEEDDDPDDSEVICSFLVALMQKNR RKDRKLGASLFTIGFAIYEVPKEV*QQQRPAVV CSTTQGAPSLSVARREASWWGLWAGL**ERALPV LFPLQSRCLRALHDP*LPPPGCALSPSHQTLHV THMPLHTHPPPRLQPHTQSHRRVLRVAARLGWR NHFPQNPAKSSRPPWGSFQPEGLRS*GAAVLVSV PECGDDTFAIHSESQQKRKRK*GREAI*ALGVG SREVETVTWVTRELGRDPWRWLWQDRMFLPRGS CALGSPHLSDAREQAAPAEGLLPVQRLQGQEQNL HQHAGGVPALPPASQRVRHRALHLRAPPGGGIH PPGLL*KEEPL*GS*KYHLRGSASAHHLRFGQS KQQQGAGCGPGVRGGQRQNKP**AKAVPTATAWQ L*SGK*GTATIPEHFQADSRR*HGDLCR*AQEG P*HSREQTQGPEDTRVHTGVLP*HDCAHGYRWL WKAQPAGVPPPLEQD*GLAENFQTL*HRPVRHHQ QLRDAKCSQRRRIPPQQPAL*HHYHAVRRQTHE HRL*QFHLLLR*AGGHVQSFSCI*QGWRWYHQA QRSGVAAAHHVCLNQAGLIQSHAGSLRISVSPSI SKAIYLKGPSSYTPTGFQAPHQSCSSSILPPTH P*SVMPSLTL**SNEVGRTNPCPFAMWRKVPAS GPSRLGSEASAPAYLALGCLQKHLPVALSTSLC* SPPSPSRCPTMGQEPNQHWVLLLWGKLTQWNRA GYFGLSNS*VWLHFEKS*SK*RHVYGW

Sequence CAPN3.fAug05

CTATTCCAGTGTTTCAGCGAGGTGGAAGTGTGATACCAATAAAGACAACTGTAGGAAAATCCACAGGCTGGATGACTGAATCCTCCTATGGACTCCGGGT TGCTCTAAGCACTAAGGGTTCTTCAGTGGGTGAGTTATATCTTGATGATGGCCATTCATTCCAATACCTCCACCAGAAGCAATTTTTGCACAGGAAGTTT TCATTCTGTTCCAGTGTTCTGATCAATAGTTTTGCTGACCAGAGGGGTCATTATCCCAGCAAGTGTGTGGTGGAGAAGATCTTGGTCTTAGGCTTCAGGA AGGAGCCATCTTCTGTGACTACCCACTCATCTGATGGTAAAGATCAGCCTGTGGCTTTTACGTATTGTGCCAAAACATCCATCCTGAGCCTGGAGAAGCT CTCACTCAACATTGCCACTGACTGGGAGGGTTCCTAAAAAAGCTCTAAAATGAATGCATAGTGTGTCTTTCCTTCAAGATGTAAATGTCAAGGAATGAGT TGGCAAATCAGTTTAAAAACACAAACTACCCAACAGAAAAATGAAATTTGCGAGAATCCCCGATTTATCATTGATGGAGCCAACAGAACTGACATCTGTC AAGGAGAGCTAGACGGGTTCCAGGGCAGCTGCCTACCTGGCCTTCCTTCCAATACAAATCATCTTGGTGGATGGTTCTCTGAGGCTCAGTCTTCGCTGAA GTCAGAAGAGGAATTGGACTCACATTGCAAAGGCACAGGGCAGGGCAGATTTCCTACAGGTGTTAGGAAGAACAACCCAGTTATGATCACCTACTGCTCT GTCTCCATTGAGGCCTAAAAAGGAAGTGAGTTTATACTGCAGTTGGAGGAACTGCCTGCAGCCTTGAGGAAAATGTCTAGTCACAAGGGAGGGACTGCTG GTTTCTCGCAGCCATTGCCTGCCTGACCCTGAACCAGCACCTTCTTTTCCGAGTCATACCCCATGATCAAAGTTTCATCGAAAACTACGCAGGGATCTTC CACTTCCAGTTCTGGCGCTATGGAGAGTGGGTGGACGTGGTTATAGATGACTGCCTGCCAACGTACAACAATCAACTGGTTTTCACCAAGTCCAACCACC GCAATGAGTTCTGGAGTGCTCTGCTGGAGAAGGCTTATGCTAAGCTCCATGGTTCCTACGAAGCTCTGAAAGGTGGGAACACCACAGAGGCCATGGAGGA CTTCACAGGAGGGGTGGCAGAGTTTTTTGAGATCAGGGATGCTCCTAGTGACATGTACAAGATCATGAAGAAAGCCATCGAGAGAGGCTCCCTCATGGGC TGCTCCATTGATGATGGCACGAACATGACCTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAGTTGATTGCACGGATGGTAAGGAATATGGATAACT CACTGCTCCAGGACTCAGACCTCGACCCCAGAGGCTCAGATGAAAGACCGACCCGGACAATCATTCCGGTTCAGTATGAGACAAGAATGGCCTGCGGGCT GGTCAGAGGTCACGCCTACTCTGTCACGGGGCTGGATGAGGTCCCGTTCAAAGGTGAGAAAGTGAAGCTGGTGCGGCTGCGGAATCCGTGGGGCCAGGTG GAGTGGAACGGTTCTTGGAGTGATAGATGGAAGGACTGGAGCTTTGTGGACAAAGATGAGAAGGCCCGTCTGCAGCACCAGGTCACTGAGGATGGAGAGT TCTGGATGTCCTATGAGGATTTCATCTACCATTTCACAAAGTTGGAGATCTGCAACCTCACGGCCGATGCTCTGCAGTCTGACAAGCTTCAGACCTGGAC AGTGTCTGTGAACGAGGGCCGCTGGGTACGGGGTTGCTCTGCCGGAGGCTGCCGCAACTTCCCAGATACTTTCTGGACCAACCCTCAGTACCGTCTGAAG CTCCTGGAGGAGGACGATGACCCTGATGACTCGGAGGTGATTTGCAGCTTCCTGGTGGCCCTGATGCAGAAGAACCGGCGGAAGGACCGGAAGCTAGGGG CCAGTCTCTTCACCATTGGCTTCGCCATCTACGAGGTTCCCAAAGAGATGCACGGGAACAAGCAGCACCTGCAGAAGGACTTCTTCCTGTACAACGCCTC CAAGGCCAGGAGCAAAACCTACATCAACATGCGGGAGGTGTCCCAGCGCTTCCGCCTGCCTCCCAGCGAGTACGTCATCGTGCCCTCCACCTACGAGCCC CACCAGGAGGGGGAATTCATCCTCCGGGTCTTCTCTGAAAAGAGGAACCTCTCTGAGGAAGTTGAAAATACCATCTCCGTGGATCGGCCAGTGCCCATCA TCTTCGTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAAGCCCTGATAAGCAAAAGCAGTC CCCACAGCCACAGCCTGGCAGCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAGATAGCAGGAGATGACATGGAGATCTGT GCAGATGAGCTCAAGAAGGTCCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACACTGGAGTCCTGCCGTAGCATGATTGCGC TCATGGATACAGATGGCTCTGGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTGGCAGAAAATTTTCAAACACTATGACAC AGACCAGTCCGGCACCATCAACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAACCAGCTCTATGACATCATTACCATGCGG TACGCAGACAAACACATGAACATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCAGAGCTTTTCATGCATTTGACAAGGATG GAGATGGTATCATCAAGCTCAACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTCATCCAAAGCCATGCAGGATCACTCAGG ATTTCAGTTTCACCCTCTATTTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCCAGGCACCTCATCAGTCATGCTCCTCCT CCATTTTACCCCCTACCCATCCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAGAACAAACCCTTGTCCCTTTGCCATGTG GAGGAAAGTGCCTGCCTCTGGTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGCTGTCTGCAGAAGCACCTGCCGGTGGCA CTCAGCACCTCCTTGTGCTAGAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGCACTGGGTTCTACTGCTGTGGGGTAAAC TAACTCAGTGGAATAGGGCTGGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTGATCTAAATAAAGGCATGTGTATGGCTG GTC

CAPN3.u.f.52 (forward primer)
CAPN3.u.r.55 (reverse primer)
Alternative donor

Frame 0

LFQCFSEVEV*YQ*RQL*ENPQAG*LNPPMDSG LL*ALRVLQWVSYILMMAIHSNTSTRSNFCTGSF HSVPVF*SIVLLTRGVIIPASVWWRRSWS*ASG RSHLL*LPTHLMVKISLWLLRIVPKHPS*AWRS SHSTLPLTGRVPKKALK*MHSVSFLQDVNVKE*V GKSV*KHKLPNRKMKFARIPDLSLMEPTELTSV KES*TGSRAAAYLAFLPIQIILVDGSLRLSLR* SQKRNWTHIAKAQGRADFLQVLGRTTQL*SPTAL SPLRPKKEVSLYCSWRNCLQP*GKCLVTREGLL VSRSHCLPDPEPAPSFPSHTP*SKFHRKLRRDL PLPVLALWRVGGRGYR*LPANVQQSTGFHQVQPP Q*VLECSAGEGLC*APWFLRSSERWEHHRGHGG LHRRGGRVF*DQGCS**HVQDHEESHRERLPHG LLH**WHEHDLWNLSFWSEHGGVDCTDGKEYG*L TAPGLRPRPQRLR*KTDPDNHSGSV*DKNGLRA GQRSRLLCHGAG*GPVQR*ESEAGAAAESVGPG GVERFLE**MEGLELCGQR*EGPSAAPGH*GWRV LDVL*GFHLPFHKVGDLQPHGRCSAV*QASDLD SVCERGPLGTGLLCRRLPQLPRYFLDQPSVPSE APGGGR*P**LGGDLQLPGGPDAEEPAEGPEARG QSLHHWLRHLRGSQRDAREQAAPAEGLLPVQRL QGQEQNLHQHAGGVPALPPASQRVRHRALHLRA PPGGGIHPPGLL*KEEPL*GS*KYHLRGSASAHH LRFGQSKQQQGAGCGPGVRGGQRQNKP**AKAV PTATAWQL*SGK*GTATIPEHFQADSRR*HGDL CR*AQEGP*HSREQTQGPEDTRVHTGVLP*HDCA HGYRWLWKAQPAGVPPPLEQD*GLAENFQTL*H RPVRHHQQLRDAKCSQRRRIPPQQPAL*HHYHA VRRQTHEHRL*QFHLLLR*AGGHVQSFSCI*QGW RWYHQAQRSGVAAAHHVCLNQAGLIQSHAGSLR ISVSPSISKAIYLKGPSSYTPTGFQAPHQSCSS SILPPTHP*SVMPSLTL**SNEVGRTNPCPFAMW RKVPASGPSRLGSEASAPAYLALGCLQKHLPVA LSTSLC*SPPSPSRCPTMGQEPNQHWVLLLWGK LTQWNRAGYFGLSNS*VWLHFEKS*SK*RHVYGW

Frame 1

YSSVSARWKCDTNKDNCRKIHRLDD*ILLWTPG CSKH*GFFSG*VIS**WPFIPIPPPEAIFAQEV FILFQCSDQ*FC*PEGSLSQQVCGGEDLGLRLQE GAIFCDYPLI*W*RSACGFYVLCQNIHPEPGEA LTQHCH*LGGFLKKL*NECIVCLSFKM*MSRNE LANQFKNTNYPTEK*NLRESPIYH*WSQQN*HLS RRARRVPGQLPTWPSFQYKSSWWMVL*GSVFAE VRRGIGLTLQRHRAGQISYRC*EEQPSYDHLLL CLH*GLKRK*VYTAVGGTACSLEENV*SQGRDCW FLAAIACLTLNQHLLFRVIPHDQSFIENYAGIF HFQFWRYGEWVDVVIDDCLPTYNNQLVFTKSNH RNEFWSALLEKAYAKLHGSYEALKGGNTTEAMED FTGGVAEFFEIRDAPSDMYKIMKKAIERGSLMG CSIDDGTNMTYGTSPSGLNMGELIARMVRNMDN SLLQDSDLDPRGSDERPTRTIIPVQYETRMACGL VRGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQV EWNGSWSDRWKDWSFVDKDEKARLQHQVTEDGE FWMSYEDFIYHFTKLEICNLTADALQSDKLQTWT VSVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLK LLEEDDDPDDSEVICSFLVALMQKNRRKDRKLG ASLFTIGFAIYEVPKEMHGNKQHLQKDFFLYNAS KARSKTYINMREVSQRFRLPPSEYVIVPSTYEP HQEGEFILRVFSEKRNLSEEVENTISVDRPVPI IFVSDRANSNKELGVDQESEEGKGKTSPDKQKQS PQPQPGSSDQESEEQQQFRNIFKQIAGDDMEIC ADELKKVLNTVVNKHKDLKTHGFTLESCRSMIA LMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDT DQSGTINSYEMRNAVNDAGFHLNNQLYDIITMR YADKHMNIDFDSFICCFVRLEGMFRAFHAFDKD GDGIIKLNVLEWLQLTMYA*TRLASSKAMQDHSG FQFHPLFPKPFTSKDPAATPLQASRHLISHAPP PFYPLPILDRSCLA*PFSKAMR*EEQTLVPLPC GGKCLPLVRAASVLKRVLLLTLL*AVCRSTCRWH SAPPCARALHHLHAVPPWARNQTSTGFYCCGVN *LSGIGLVTLGCPTHKFGCILKKADLNKGMCMA G

Frame 2

IPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRV ALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKF SFCSSVLINSFADQRGHYPSKCVVEKILVLGFR KEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKL SLNIATDWEGS*KSSKMNA*CVFPSRCKCQGMS WQISLKTQTTQQKNEICENPRFIIDGANRTDIC QGELDGFQGSCLPGLPSNTNHLGGWFSEAQSSLK SEEELDSHCKGTGQGRFPTGVRKNNPVMITYCS VSIEA*KGSEFILQLEELPAALRKMSSHKGGTA GFSQPLPA*P*TSTFFSESYPMIKVSSKTTQGSS TSSSGAMESGWTWL*MTACQRTTINWFSPSPTT AMSSGVLCWRRLMLSSMVPTKL*KVGTPQRPWR TSQEGWQSFLRSGMLLVTCTRS*RKPSREAPSWA APLMMART*PMEPLLLV*TWGS*LHGW*GIWIT HCSRTQTSTPEAQMKDRPGQSFRFSMRQEWPAG WSEVTPTLSRGWMRSRSKVRK*SWCGCGIRGARW SGTVLGVIDGRTGALWTKMRRPVCSTRSLRMES SGCPMRISSTISQSWRSATSRPMLCSLTSFRPG QCL*TRAAGYGVALPEAAATSQILSGPTLSTV*S SWRRTMTLMTRR*FAASWWP*CRRTGGRTGS*G PVSSPLASPSTRFPKRCTGTSSTCRRTSSCTTP PRPGAKPTSTCGRCPSASACLPASTSSCPPPTSP TRRGNSSSGSSLKRGTSLRKLKIPSPWIGQCPS SSFRTEQTATRSWVWTRSQRRAKAKQALISKSS PHSHSLAALIRKVRNSNNSGTFSSR*QEMTWRSV QMSSRRSLTQS*TNTRT*RHTGSHWSPAVA*LR SWIQMALESSTCRSSTTSGTRLRPGRKFSNTMT QTSPAPSTATRCEMQSTTQDSTSTTSSMTSLPCG TQTNT*TSTLTVSSAASLGWRACSELFMHLTRM EMVSSSSTFWSGCSSPCMPEPGWPHPKPCRITQ DFSFTLYFQSHLPQRTQQLHPYRLPGTSSVMLLL HFTPYPSLIGHA*PDPLVKQ*GRKNKPLSLCHV EESACLWSEPPRF*SECSCLPCSRLSAEAPAGG TQHLLVLEPSITFTLSHHGPGTKPALGSTAVG*T NSVE*GWLLWAVQLISLAAF*KKLI*IKACVWL V

Sequence CAPN3.eAug05

CTATTCCAGTGTTTCAGCGAGGTGGAAGTGTGATACCAATAAAGACAACTGTAGGAAAATCCACAGGCTGGATGACTGAATCCTCCTATGGACTCCGGGT TGCTCTAAGCACTAAGGGTTCTTCAGTGGGTGAGTTATATCTTGATGATGGCCATTCATTCCAATACCTCCACCAGAAGCAATTTTTGCACAGGAAGTTT TCATTCTGTTCCAGTGTTCTGATCAATAGTTTTGCTGACCAGAGGGGTCATTATCCCAGCAAGTGTGTGGTGGAGAAGATCTTGGTCTTAGGCTTCAGGA AGGAGCCATCTTCTGTGACTACCCACTCATCTGATGGTAAAGATCAGCCTGTGGCTTTTACGTATTGTGCCAAAACATCCATCCTGAGCCTGGAGAAGCT CTCACTCAACATTGCCACTGACTGGGAGGGTTCCTAAAAAAGCTCTAAAATGAATGCATAGTGTGTCTTTCCTTCAAGATGTAAATGTCAAGGAATGAGT TGGCAAATCAGTTTAAAAACACAAACTACCCAACAGAAAAATGAAATTTGCGAGAATCCCCGATTTATCATTGATGGAGCCAACAGAACTGACATCTGTC AAGGAGAGCTAGGGGACTGCTGGTTTCTCGCAGCCATTGCCTGCCTGACCCTGAACCAGCACCTTCTTTTCCGAGTCATACCCCATGATCAAAGTTTCAT CGAAAACTACGCAGGGATCTTCCACTTCCAGTTCTGGCGCTATGGAGAGTGGGTGGACGTGGTTATAGATGACTGCCTGCCAACGTACAACAATCAACTG GTTTTCACCAAGTCCAACCACCGCAATGAGTTCTGGAGTGCTCTGCTGGAGAAGGCTTATGCTAAGCTCCATGGTTCCTACGAAGCTCTGAAAGGTGGGA ACACCACAGAGGCCATGGAGGACTTCACAGGAGGGGTGGCAGAGTTTTTTGAGATCAGGGATGCTCCTAGTGACATGTACAAGATCATGAAGAAAGCCAT CGAGAGAGGCTCCCTCATGGGCTGCTCCATTGATGATGGCACGAACATGACCTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAGTTGATTGCACGG ATGGTAAGGAATATGGATAACTCACTGCTCCAGGACTCAGACCTCGACCCCAGAGGCTCAGATGAAAGACCGACCCGGACAATCATTCCGGTTCAGTATG AGACAAGAATGGCCTGCGGGCTGGTCAGAGGTCACGCCTACTCTGTCACGGGGCTGGATGAGGTCCCGTTCAAAGGTGAGAAAGTGAAGCTGGTGCGGCT GCGGAATCCGTGGGGCCAGGTGGAGTGGAACGGTTCTTGGAGTGATAGATGGAAGGACTGGAGCTTTGTGGACAAAGATGAGAAGGCCCGTCTGCAGCAC CAGGTCACTGAGGATGGAGAGTTCTGGATGTCCTATGAGGATTTCATCTACCATTTCACAAAGTTGGAGATCTGCAACCTCACGGCCGATGCTCTGCAGT CTGACAAGCTTCAGACCTGGACAGTGTCTGTGAACGAGGGCCGCTGGGTACGGGGTTGCTCTGCCGGAGGCTGCCGCAACTTCCCAGATACTTTCTGGAC CAACCCTCAGTACCGTCTGAAGCTCCTGGAGGAGGACGATGACCCTGATGACTCGGAGGTGATTTGCAGCTTCCTGGTGGCCCTGATGCAGAAGAACCGG CGGAAGGACCGGAAGCTAGGGGCCAGTCTCTTCACCATTGGCTTCGCCATCTACGAGGTTCCCAAAGAGATGCACGGGAACAAGCAGCACCTGCAGAAGG ACTTCTTCCTGTACAACGCCTCCAAGGCCAGGAGCAAAACCTACATCAACATGCGGGAGGTGTCCCAGCGCTTCCGCCTGCCTCCCAGCGAGTACGTCAT CGTGCCCTCCACCTACGAGCCCCACCAGGAGGGGGAATTCATCCTCCGGGTCTTCTCTGAAAAGAGGAACCTCTCTGAGGAAGTTGAAAATACCATCTCC GTGGATCGGCCAGTGCCCATCATCTTCGTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAA GCCCTGATAAGCAAAAGCAGTCCCCACAGCCACAGCCTGGCAGCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAGATAGC AGGAGATGACATGGAGATCTGTGCAGATGAGCTCAAGAAGGTCCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACACTGGAG TCCTGCCGTAGCATGATTGCGCTCATGGATACAGATGGCTCTGGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTGGCAGA AAATTTTCAAACACTATGACACAGACCAGTCCGGCACCATCAACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAACCAGCT CTATGACATCATTACCATGCGGTACGCAGACAAACACATGAACATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCAGAGCT TTTCATGCATTTGACAAGGATGGAGATGGTATCATCAAGCTCAACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTCATCCA AAGCCATGCAGGATCACTCAGGATTTCAGTTTCACCCTCTATTTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCCAGGCA CCTCATCAGTCATGCTCCTCCTCCATTTTACCCCCTACCCATCCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAGAACAA ACCCTTGTCCCTTTGCCATGTGGAGGAAAGTGCCTGCCTCTGGTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGCTGTCT GCAGAAGCACCTGCCGGTGGCACTCAGCACCTCCTTGTGCTAGAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGCACTGG GTTCTACTGCTGTGGGGTAAACTAACTCAGTGGAATAGGGCTGGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTGATCTA AATAAAGGCATGTGTATGGCTGGTC

CAPN3.u.f.52 (forward primer)
CAPN3.u.r.55 (reverse primer)
Alternative donor

Frame 0

LFQCFSEVEV*YQ*RQL*ENPQAG*LNPPMDSG LL*ALRVLQWVSYILMMAIHSNTSTRSNFCTGSF HSVPVF*SIVLLTRGVIIPASVWWRRSWS*ASG RSHLL*LPTHLMVKISLWLLRIVPKHPS*AWRS SHSTLPLTGRVPKKALK*MHSVSFLQDVNVKE*V GKSV*KHKLPNRKMKFARIPDLSLMEPTELTSV KES*GTAGFSQPLPA*P*TSTFFSESYPMIKVS SKTTQGSSTSSSGAMESGWTWL*MTACQRTTINW FSPSPTTAMSSGVLCWRRLMLSSMVPTKL*KVG TPQRPWRTSQEGWQSFLRSGMLLVTCTRS*RKP SREAPSWAAPLMMART*PMEPLLLV*TWGS*LHG W*GIWITHCSRTQTSTPEAQMKDRPGQSFRFSM RQEWPAGWSEVTPTLSRGWMRSRSKVRK*SWCG CGIRGARWSGTVLGVIDGRTGALWTKMRRPVCST RSLRMESSGCPMRISSTISQSWRSATSRPMLCS LTSFRPGQCL*TRAAGYGVALPEAAATSQILSG PTLSTV*SSWRRTMTLMTRR*FAASWWP*CRRTG GRTGS*GPVSSPLASPSTRFPKRCTGTSSTCRR TSSCTTPPRPGAKPTSTCGRCPSASACLPASTS SCPPPTSPTRRGNSSSGSSLKRGTSLRKLKIPSP WIGQCPSSSFRTEQTATRSWVWTRSQRRAKAKQ ALISKSSPHSHSLAALIRKVRNSNNSGTFSSR* QEMTWRSVQMSSRRSLTQS*TNTRT*RHTGSHWS PAVA*LRSWIQMALESSTCRSSTTSGTRLRPGR KFSNTMTQTSPAPSTATRCEMQSTTQDSTSTTS SMTSLPCGTQTNT*TSTLTVSSAASLGWRACSEL FMHLTRMEMVSSSSTFWSGCSSPCMPEPGWPHP KPCRITQDFSFTLYFQSHLPQRTQQLHPYRLPG TSSVMLLLHFTPYPSLIGHA*PDPLVKQ*GRKNK PLSLCHVEESACLWSEPPRF*SECSCLPCSRLS AEAPAGGTQHLLVLEPSITFTLSHHGPGTKPAL GSTAVG*TNSVE*GWLLWAVQLISLAAF*KKLI* IKACVWLV

Frame 1

YSSVSARWKCDTNKDNCRKIHRLDD*ILLWTPG CSKH*GFFSG*VIS**WPFIPIPPPEAIFAQEV FILFQCSDQ*FC*PEGSLSQQVCGGEDLGLRLQE GAIFCDYPLI*W*RSACGFYVLCQNIHPEPGEA LTQHCH*LGGFLKKL*NECIVCLSFKM*MSRNE LANQFKNTNYPTEK*NLRESPIYH*WSQQN*HLS RRARGLLVSRSHCLPDPEPAPSFPSHTP*SKFH RKLRRDLPLPVLALWRVGGRGYR*LPANVQQST GFHQVQPPQ*VLECSAGEGLC*APWFLRSSERWE HHRGHGGLHRRGGRVF*DQGCS**HVQDHEESH RERLPHGLLH**WHEHDLWNLSFWSEHGGVDCT DGKEYG*LTAPGLRPRPQRLR*KTDPDNHSGSV* DKNGLRAGQRSRLLCHGAG*GPVQR*ESEAGAA AESVGPGGVERFLE**MEGLELCGQR*EGPSAA PGH*GWRVLDVL*GFHLPFHKVGDLQPHGRCSAV *QASDLDSVCERGPLGTGLLCRRLPQLPRYFLD QPSVPSEAPGGGR*P**LGGDLQLPGGPDAEEP AEGPEARGQSLHHWLRHLRGSQRDAREQAAPAEG LLPVQRLQGQEQNLHQHAGGVPALPPASQRVRH RALHLRAPPGGGIHPPGLL*KEEPL*GS*KYHL RGSASAHHLRFGQSKQQQGAGCGPGVRGGQRQNK P**AKAVPTATAWQL*SGK*GTATIPEHFQADS RR*HGDLCR*AQEGP*HSREQTQGPEDTRVHTG VLP*HDCAHGYRWLWKAQPAGVPPPLEQD*GLAE NFQTL*HRPVRHHQQLRDAKCSQRRRIPPQQPA L*HHYHAVRRQTHEHRL*QFHLLLR*AGGHVQS FSCI*QGWRWYHQAQRSGVAAAHHVCLNQAGLIQ SHAGSLRISVSPSISKAIYLKGPSSYTPTGFQA PHQSCSSSILPPTHP*SVMPSLTL**SNEVGRT NPCPFAMWRKVPASGPSRLGSEASAPAYLALGCL QKHLPVALSTSLC*SPPSPSRCPTMGQEPNQHW VLLLWGKLTQWNRAGYFGLSNS*VWLHFEKS*S K*RHVYGW

Frame 2

IPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRV ALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKF SFCSSVLINSFADQRGHYPSKCVVEKILVLGFR KEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKL SLNIATDWEGS*KSSKMNA*CVFPSRCKCQGMS WQISLKTQTTQQKNEICENPRFIIDGANRTDIC QGELGDCWFLAAIACLTLNQHLLFRVIPHDQSFI ENYAGIFHFQFWRYGEWVDVVIDDCLPTYNNQL VFTKSNHRNEFWSALLEKAYAKLHGSYEALKGG NTTEAMEDFTGGVAEFFEIRDAPSDMYKIMKKAI ERGSLMGCSIDDGTNMTYGTSPSGLNMGELIAR MVRNMDNSLLQDSDLDPRGSDERPTRTIIPVQY ETRMACGLVRGHAYSVTGLDEVPFKGEKVKLVRL RNPWGQVEWNGSWSDRWKDWSFVDKDEKARLQH QVTEDGEFWMSYEDFIYHFTKLEICNLTADALQ SDKLQTWTVSVNEGRWVRGCSAGGCRNFPDTFWT NPQYRLKLLEEDDDPDDSEVICSFLVALMQKNR RKDRKLGASLFTIGFAIYEVPKEMHGNKQHLQK DFFLYNASKARSKTYINMREVSQRFRLPPSEYVI VPSTYEPHQEGEFILRVFSEKRNLSEEVENTIS VDRPVPIIFVSDRANSNKELGVDQESEEGKGKT SPDKQKQSPQPQPGSSDQESEEQQQFRNIFKQIA GDDMEICADELKKVLNTVVNKHKDLKTHGFTLE SCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQ KIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQL YDIITMRYADKHMNIDFDSFICCFVRLEGMFRA FHAFDKDGDGIIKLNVLEWLQLTMYA*TRLASS KAMQDHSGFQFHPLFPKPFTSKDPAATPLQASRH LISHAPPPFYPLPILDRSCLA*PFSKAMR*EEQ TLVPLPCGGKCLPLVRAASVLKRVLLLTLL*AV CRSTCRWHSAPPCARALHHLHAVPPWARNQTSTG FYCCGVN*LSGIGLVTLGCPTHKFGCILKKADL NKGMCMAG

Sequence CAPN3.cAug05

CACTCTCTTTCTCTCTCCCTCTGGCATGCATGCTGCTGGTAGGAGACCCCCAAGTCAACATTGCTTCAGAAATCCTTTAGCACTCATTTCTCAGGAGAAC TTATGGCTTCAGAATCACAGCTCGGTTTTTAAGATGGACATAACCTGTACGACCTTCTGATGGGCTTTCAACTTTGAACTGGATGTGGACACTTTTCTCT CAGATGACAGAATTACTCCAACTTCCCCTTTGCAGTTGCTTCCTTTCCTTGAAGGTAGCTGTATCTTATTTTCTTTAAAAAGCTTTTTCTTCCAAAGCCA CTTGCCATGCCGACCGTCATTAGCGCATCTGTGGCTCCAAGGACAGCGGCTGAGCCCCGGTCCCCAGGGCCAGTTCCTCACCCGGCCCAGAGCAAGGCCA CTGAGGCTGGGGGTGGAAACCCAAGTGGCATCTATTCAGCCATCATCAGCCGCAATTTTCCTATTATCGGAGTGAAAGAGAAGACATTCGAGCAACTTCA CAAGAAATGTCTAGAAAAGAAAGTTCTTTATGTGGACCCTGAGTTCCCACCGGATGAGACCTCTCTCTTTTATAGCCAGAAGTTCCCCATCCAGTTCGTC TGGAAGAGACCTCCGGAAATTTGCGAGAATCCCCGATTTATCATTGATGGAGCCAACAGAACTGACATCTGTCAAGGAGAGCTAGGGGACTGCTGGTTTC TCGCAGCCATTGCCTGCCTGACCCTGAACCAGCACCTTCTTTTCCGAGTCATACCCCATGATCAAAGTTTCATCGAAAACTACGCAGGGATCTTCCACTT CCAGTTCTGGCGCTATGGAGAGTGGGTGGACGTGGTTATAGATGACTGCCTGCCAACGTACAACAATCAACTGGTTTTCACCAAGTCCAACCACCGCAAT GAGTTCTGGAGTGCTCTGCTGGAGAAGGCTTATGCTAAGCTCCATGGTTCCTACGAAGCTCTGAAAGGTGGGAACACCACAGAGGCCATGGAGGACTTCA CAGGAGGGGTGGCAGAGTTTTTTGAGATCAGGGATGCTCCTAGTGACATGTACAAGATCATGAAGAAAGCCATCGAGAGAGGCTCCCTCATGGGCTGCTC CATTGATGATGGCACGAACATGACCTATGGAACCTCTCCTTCTGGTCTGAACATGGGGGAGTTGATTGCACGGATGGTAAGGAATATGGATAACTCACTG CTCCAGGACTCAGACCTCGACCCCAGAGGCTCAGATGAAAGACCGACCCGGACAATCATTCCGGTTCAGTATGAGACAAGAATGGCCTGCGGGCTGGTCA GAGGTCACGCCTACTCTGTCACGGGGCTGGATGAGGTCCCGTTCAAAGGTGAGAAAGTGAAGCTGGTGCGGCTGCGGAATCCGTGGGGCCAGGTGGAGTG GAACGGTTCTTGGAGTGATAGATGGAAGGACTGGAGCTTTGTGGACAAAGATGAGAAGGCCCGTCTGCAGCACCAGGTCACTGAGGATGGAGAGTTCTGG ATGTCCTATGAGGATTTCATCTACCATTTCACAAAGTTGGAGATCTGCAACCTCACGGCCGATGCTCTGCAGTCTGACAAGCTTCAGACCTGGACAGTGT CTGTGAACGAGGGCCGCTGGGTACGGGGTTGCTCTGCCGGAGGCTGCCGCAACTTCCCAGATACTTTCTGGACCAACCCTCAGTACCGTCTGAAGCTCCT GGAGGAGGACGATGACCCTGATGACTCGGAGGTGATTTGCAGCTTCCTGGTGGCCCTGATGCAGAAGAACCGGCGGAAGGACCGGAAGCTAGGGGCCAGT CTCTTCACCATTGGCTTCGCCATCTACGAGGTTCCCAAAGAGATGCACGGGAACAAGCAGCACCTGCAGAAGGACTTCTTCCTGTACAACGCCTCCAAGG CCAGGAGCAAAACCTACATCAACATGCGGGAGGTGTCCCAGCGCTTCCGCCTGCCTCCCAGCGAGTACGTCATCGTGCCCTCCACCTACGAGCCCCACCA GGAGGGGGAATTCATCCTCCGGGTCTTCTCTGAAAAGAGGAACCTCTCTGAGGAAGTTGAAAATACCATCTCCGTGGATCGGCCAGTGCCCATCATCTTC GTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAAGCCCTGATAAGCAAAAGCAGTCCCCAC AGCCACAGCCTGGCAGCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAGATAGCAGGAGATGACATGGAGATCTGTGCAGA TGAGCTCAAGAAGGTCCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACACTGGAGTCCTGCCGTAGCATGATTGCGCTCATG GATACAGATGGCTCTGGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTGGCAGAAAATTTTCAAACACTATGACACAGACC AGTCCGGCACCATCAACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAACCAGCTCTATGACATCATTACCATGCGGTACGC AGACAAACACATGAACATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCAGAGCTTTTCATGCATTTGACAAGGATGGAGAT GGTATCATCAAGCTCAACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTCATCCAAAGCCATGCAGGATCACTCAGGATTTC AGTTTCACCCTCTATTTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCCAGGCACCTCATCAGTCATGCTCCTCCTCCATT TTACCCCCTACCCATCCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAGAACAAACCCTTGTCCCTTTGCCATGTGGAGGA AAGTGCCTGCCTCTGGTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGCTGTCTGCAGAAGCACCTGCCGGTGGCACTCAG CACCTCCTTGTGCTAGAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGCACTGGGTTCTACTGCTGTGGGGTAAACTAACT CAGTGGAATAGGGCTGGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTGATCTAAATAAAGGCATGTGTATGGCTGGTC

CAPN3.u.f.52 (forward primer)
CAPN3.u.r.55 (reverse primer)
Alternative donor

Frame 0

HSLSLSLWHACCW*ETPKSTLLQKSFSTHFSGE LMASESQLGF*DGHNLYDLLMGFQL*TGCGHFSL R*QNYSNFPFAVASFP*R*LYLIFFKKLFLPKP LAMPTVISASVAPRTAAEPRSPGPVPHPAQSKA TEAGGGNPSGIYSAIISRNFPIIGVKEKTFEQLH KKCLEKKVLYVDPEFPPDETSLFYSQKFPIQFV WKRPPEICENPRFIIDGANRTDICQGELGDCWF LAAIACLTLNQHLLFRVIPHDQSFIENYAGIFHF QFWRYGEWVDVVIDDCLPTYNNQLVFTKSNHRN EFWSALLEKAYAKLHGSYEALKGGNTTEAMEDF TGGVAEFFEIRDAPSDMYKIMKKAIERGSLMGCS IDDGTNMTYGTSPSGLNMGELIARMVRNMDNSL LQDSDLDPRGSDERPTRTIIPVQYETRMACGLV RGHAYSVTGLDEVPFKGEKVKLVRLRNPWGQVEW NGSWSDRWKDWSFVDKDEKARLQHQVTEDGEFW MSYEDFIYHFTKLEICNLTADALQSDKLQTWTV SVNEGRWVRGCSAGGCRNFPDTFWTNPQYRLKLL EEDDDPDDSEVICSFLVALMQKNRRKDRKLGAS LFTIGFAIYEVPKEMHGNKQHLQKDFFLYNASK ARSKTYINMREVSQRFRLPPSEYVIVPSTYEPHQ EGEFILRVFSEKRNLSEEVENTISVDRPVPIIF VSDRANSNKELGVDQESEEGKGKTSPDKQKQSP QPQPGSSDQESEEQQQFRNIFKQIAGDDMEICAD ELKKVLNTVVNKHKDLKTHGFTLESCRSMIALM DTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTD QSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYA DKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGD GIIKLNVLEWLQLTMYA*TRLASSKAMQDHSGF QFHPLFPKPFTSKDPAATPLQASRHLISHAPPPF YPLPILDRSCLA*PFSKAMR*EEQTLVPLPCGG KCLPLVRAASVLKRVLLLTLL*AVCRSTCRWHS APPCARALHHLHAVPPWARNQTSTGFYCCGVN*L SGIGLVTLGCPTHKFGCILKKADLNKGMCMAG

Frame 1

TLFLSPSGMHAAGRRPPSQHCFRNPLALISQEN LWLQNHSSVFKMDITCTTF*WAFNFELDVDTFL SDDRITPTSPLQLLPFLEGSCILFSLKSFFFQSH LPCRPSLAHLWLQGQRLSPGPQGQFLTRPRARP LRLGVETQVASIQPSSAAIFLLSE*KRRHSSNF TRNV*KRKFFMWTLSSHRMRPLSFIARSSPSSSS GRDLRKFARIPDLSLMEPTELTSVKES*GTAGF SQPLPA*P*TSTFFSESYPMIKVSSKTTQGSST SSSGAMESGWTWL*MTACQRTTINWFSPSPTTAM SSGVLCWRRLMLSSMVPTKL*KVGTPQRPWRTS QEGWQSFLRSGMLLVTCTRS*RKPSREAPSWAA PLMMART*PMEPLLLV*TWGS*LHGW*GIWITHC SRTQTSTPEAQMKDRPGQSFRFSMRQEWPAGWS EVTPTLSRGWMRSRSKVRK*SWCGCGIRGARWS GTVLGVIDGRTGALWTKMRRPVCSTRSLRMESSG CPMRISSTISQSWRSATSRPMLCSLTSFRPGQC L*TRAAGYGVALPEAAATSQILSGPTLSTV*SS WRRTMTLMTRR*FAASWWP*CRRTGGRTGS*GPV SSPLASPSTRFPKRCTGTSSTCRRTSSCTTPPR PGAKPTSTCGRCPSASACLPASTSSCPPPTSPT RRGNSSSGSSLKRGTSLRKLKIPSPWIGQCPSSS FRTEQTATRSWVWTRSQRRAKAKQALISKSSPH SHSLAALIRKVRNSNNSGTFSSR*QEMTWRSVQ MSSRRSLTQS*TNTRT*RHTGSHWSPAVA*LRSW IQMALESSTCRSSTTSGTRLRPGRKFSNTMTQT SPAPSTATRCEMQSTTQDSTSTTSSMTSLPCGT QTNT*TSTLTVSSAASLGWRACSELFMHLTRMEM VSSSSTFWSGCSSPCMPEPGWPHPKPCRITQDF SFTLYFQSHLPQRTQQLHPYRLPGTSSVMLLLH FTPYPSLIGHA*PDPLVKQ*GRKNKPLSLCHVEE SACLWSEPPRF*SECSCLPCSRLSAEAPAGGTQ HLLVLEPSITFTLSHHGPGTKPALGSTAVG*TN SVE*GWLLWAVQLISLAAF*KKLI*IKACVWLV

Frame 2

LSFSLPLACMLLVGDPQVNIASEIL*HSFLRRT YGFRITARFLRWT*PVRPSDGLSTLNWMWTLFS QMTELLQLPLCSCFLSLKVAVSYFL*KAFSSKA TCHADRH*RICGSKDSG*APVPRASSSPGPEQGH *GWGWKPKWHLFSHHQPQFSYYRSEREDIRATS QEMSRKESSLCGP*VPTG*DLSLL*PEVPHPVR LEETSGNLRESPIYH*WSQQN*HLSRRARGLLVS RSHCLPDPEPAPSFPSHTP*SKFHRKLRRDLPL PVLALWRVGGRGYR*LPANVQQSTGFHQVQPPQ *VLECSAGEGLC*APWFLRSSERWEHHRGHGGLH RRGGRVF*DQGCS**HVQDHEESHRERLPHGLL H**WHEHDLWNLSFWSEHGGVDCTDGKEYG*LT APGLRPRPQRLR*KTDPDNHSGSV*DKNGLRAGQ RSRLLCHGAG*GPVQR*ESEAGAAAESVGPGGV ERFLE**MEGLELCGQR*EGPSAAPGH*GWRVL DVL*GFHLPFHKVGDLQPHGRCSAV*QASDLDSV CERGPLGTGLLCRRLPQLPRYFLDQPSVPSEAP GGGR*P**LGGDLQLPGGPDAEEPAEGPEARGQ SLHHWLRHLRGSQRDAREQAAPAEGLLPVQRLQG QEQNLHQHAGGVPALPPASQRVRHRALHLRAPP GGGIHPPGLL*KEEPL*GS*KYHLRGSASAHHL RFGQSKQQQGAGCGPGVRGGQRQNKP**AKAVPT ATAWQL*SGK*GTATIPEHFQADSRR*HGDLCR *AQEGP*HSREQTQGPEDTRVHTGVLP*HDCAH GYRWLWKAQPAGVPPPLEQD*GLAENFQTL*HRP VRHHQQLRDAKCSQRRRIPPQQPAL*HHYHAVR RQTHEHRL*QFHLLLR*AGGHVQSFSCI*QGWR WYHQAQRSGVAAAHHVCLNQAGLIQSHAGSLRIS VSPSISKAIYLKGPSSYTPTGFQAPHQSCSSSI LPPTHP*SVMPSLTL**SNEVGRTNPCPFAMWR KVPASGPSRLGSEASAPAYLALGCLQKHLPVALS TSLC*SPPSPSRCPTMGQEPNQHWVLLLWGKLT QWNRAGYFGLSNS*VWLHFEKS*SK*RHVYGW

Sequence CAPN3.mAug05

CCATTCTGTGATATTTATTGAGCACCTACTATGTTCCAGGCACTGTCCTAGGCACTAAGGATAGAGTAGTGAAGTAAACAGAAAGAAATCCCTGCCTTCA TGGAGCTTAATATTCTAACATGAGACAATAATGGATAGGAAAAACATATGTAGCATGTTAGATTTGGAGAGGTGATATGGAGCAAAAATAAAGTAGGGAA GAGGGATAGGAGGTGTTGGGGATGCTTGAAATTTTAGGTTAGCATGGCCAGGAAAGCCACATCCTGTCCCTGGCCACCACAGATGAGCTCATAGCCCCTG CCACTCTGATCTCTGTCCTTGGAAGATGCACCAGGTCCATGGGTAGGTGGCTGGGTCATGCCTTTGGGGGGCTCTGAGCAATACTAACAAGAACCTGCGT GCCTGGGCTTGGCTGTCGGGGATGGTGCTGACATGGGGCTGGTTCCTGGGGTTGGGGTGTTCCAGGGGTTCTCTAGAGGCTGGTTCTGGCTTGGCTGCCA GGAAGCCGTGCACCAGAGCAAACCGTCCACGGGCCTCCTGCTTGCTTCTGGTGACACTGAGACCCCACATGTCTGTATTCCTCACAGGGAAGTTGAAAAT ACCATCTCCGTGGATCGGCCAGTGGTGAGTGGTTTAGATCTTCTGTGCGAAAAGTCCAGAGGGTCCCCTTCCCTGACCATGCAGGGGACAGATGGTGCAG GGGAGAATGGGCACTGGCAGAGGGAATGGGAGTCTGGGCTGTGCTGAGCAGTCCCTCCTTGGCACTGCAAATCCTACTTTGGCATGGCCAGAAGTAATCG GCCTTAAGCACCGGGGGCCATTGAGGCAGTTCAGGGGCTGGGAAATATGGAAGAGGGTCCTGGAAAGGAGAAGCAATTTGAACAATCGGAGGGAACAAGG CCACAGGAAGGGATGACAAGAGCCGCAGCGAACACTGGATTCTGAGACTGGATAACATTGGATTTCACACATAGAGAAAAGAAAGTAAGCTGGTGCCGGA CCTGGTGTTGACACTTGGATCCTCCACTTACCAGCGGGGTGACCTGGACAATTTCTGTAATCCCTCTCACTCAGTTTCCTACTCAGTAAAACGGGGATGA TAATGTGCCTTGCAAGGCTTTTGTGAGGCTTCATCAATGAGGTGATGTATGTGAAGTGTCTGGCACAGCATGGGCACTCAAACAGAGGTGCTTTTTCACA CTTTACACCTTACAAGGTACTTTTCACATGTGTCATCGCGATACTTGCAAGGTTGCTGAGAGGTAGATGGGGTTATAATCCCTGGTGTTCAAGAAAGGAA GCAGAGGCTCAATGGGGTTGAATGACTTCTCTGAGTTCACAGAGCTCAGTAAGTGGCAGGGTTGGAACTCACATTCAGACTCTCTGACTCCAGACTTAGG TTTTTCCGCACCTCCACGCTGAGGCCAGCCCCAGGCAGTGAGAAGCCCAAAGTCCGAAGCACAGAGTGCTGTGTGTTGGGCTCTGTGTGTTGAGGAGTCT TGTGACTGCCTTGGGGCTTTGGGCTGTAGTCAGCTGACAGTCCTTTGTGCTCTGTGGGGATGACGTAGGCCAATGGGAGGACAAATGCCCCTCTGAACTG TCTTCTGGGCAGTGACAGTCATGGTCATAATCCTGACCCTGAGCCAGTGCCAGGTCTCCAAGTGCCTTCTGAATGACCACAGGCGATTGGTTTTAGTGGT AGGTGTGTGGGGATCTGTTCTGGTCATCTGGATGCTGGTCATCGGTGTGCAGTATTGATCAGGACCTGCAAACCCAAAAGCTTATGGGAGCTGGCACGTC ACCCCATCATCTTCGTTTCGGACAGAGCAAACAGCAACAAGGAGCTGGGTGTGGACCAGGAGTCAGAGGAGGGCAAAGGCAAAACAAGCCCTGATAAGCA AAAGCAGTCCCCACAGCCACAGCCTGGCAGCTCTGATCAGGAAAGTGAGGAACAGCAACAATTCCGGAACATTTTCAAGCAGATAGCAGGAGATGACATG GAGATCTGTGCAGATGAGCTCAAGAAGGTCCTTAACACAGTCGTGAACAAACACAAGGACCTGAAGACACACGGGTTCACACTGGAGTCCTGCCGTAGCA TGATTGCGCTCATGGATACAGATGGCTCTGGAAAGCTCAACCTGCAGGAGTTCCACCACCTCTGGAACAAGATTAAGGCCTGGCAGAAAATTTTCAAACA CTATGACACAGACCAGTCCGGCACCATCAACAGCTACGAGATGCGAAATGCAGTCAACGACGCAGGATTCCACCTCAACAACCAGCTCTATGACATCATT ACCATGCGGTACGCAGACAAACACATGAACATCGACTTTGACAGTTTCATCTGCTGCTTCGTTAGGCTGGAGGGCATGTTCAGAGCTTTTCATGCATTTG ACAAGGATGGAGATGGTATCATCAAGCTCAACGTTCTGGAGTGGCTGCAGCTCACCATGTATGCCTGAACCAGGCTGGCCTCATCCAAAGCCATGCAGGA TCACTCAGGATTTCAGTTTCACCCTCTATTTCCAAAGCCATTTACCTCAAAGGACCCAGCAGCTACACCCCTACAGGCTTCCAGGCACCTCATCAGTCAT GCTCCTCCTCCATTTTACCCCCTACCCATCCTTGATCGGTCATGCCTAGCCTGACCCTTTAGTAAAGCAATGAGGTAGGAAGAACAAACCCTTGTCCCTT TGCCATGTGGAGGAAAGTGCCTGCCTCTGGTCCGAGCCGCCTCGGTTCTGAAGCGAGTGCTCCTGCTTACCTTGCTCTAGGCTGTCTGCAGAAGCACCTG CCGGTGGCACTCAGCACCTCCTTGTGCTAGAGCCCTCCATCACCTTCACGCTGTCCCACCATGGGCCAGGAACCAAACCAGCACTGGGTTCTACTGCTGT GGGGTAAACTAACTCAGTGGAATAGGGCTGGTTACTTTGGGCTGTCCAACTCATAAGTTTGGCTGCATTTTGAAAAAAGCTGATCTAAATAAAGGCATGT GTATGGCTGGTC

CAPN3.u.f.52 (forward primer)
CAPN3.u.r.55 (reverse primer)
Alternative donor

Frame 0

PFCDIY*APTMFQALS*ALRIE**SKQKEIPAF MELNILT*DNNG*EKHM*HVRFGEVIWSKNKVGK RDRRCWGCLKF*VSMARKATSCPWPPQMSS*PL PL*SLSLEDAPGPWVGGWVMPLGGSEQY*QEPA CLGLAVGDGADMGLVPGVGVFQGFSRGWFWLGCQ EAVHQSKPSTGLLLASGDTETPHVCIPHREVEN TISVDRPVVSGLDLLCEKSRGSPSLTMQGTDGA GENGHWQREWESGLC*AVPPWHCKSYFGMARSNR P*APGAIEAVQGLGNMEEGPGKEKQFEQSEGTR PQEGMTRAAANTGF*DWITLDFTHREKKVSWCR TWC*HLDPPLTSGVTWTISVIPLTQFPTQ*NGDD NVPCKAFVRLHQ*GDVCEVSGTAWALKQRCFFT LYTLQGTFHMCHRDTCKVAER*MGL*SLVFKKG SRGSMGLNDFSEFTELSKWQGWNSHSDSLTPDLG FSAPPR*GQPQAVRSPKSEAQSAVCWALCVEES CDCLGALGCSQLTVLCALWG*RRPMGGQMPL*T VFWAVTVMVIILTLSQCQVSKCLLNDHRRLVLVV GVWGSVLVIWMLVIGVQY*SGPANPKAYGSWHV TPSSSFRTEQTATRSWVWTRSQRRAKAKQALIS KSSPHSHSLAALIRKVRNSNNSGTFSSR*QEMTW RSVQMSSRRSLTQS*TNTRT*RHTGSHWSPAVA *LRSWIQMALESSTCRSSTTSGTRLRPGRKFSN TMTQTSPAPSTATRCEMQSTTQDSTSTTSSMTSL PCGTQTNT*TSTLTVSSAASLGWRACSELFMHL TRMEMVSSSSTFWSGCSSPCMPEPGWPHPKPCR ITQDFSFTLYFQSHLPQRTQQLHPYRLPGTSSVM LLLHFTPYPSLIGHA*PDPLVKQ*GRKNKPLSL CHVEESACLWSEPPRF*SECSCLPCSRLSAEAP AGGTQHLLVLEPSITFTLSHHGPGTKPALGSTAV G*TNSVE*GWLLWAVQLISLAAF*KKLI*IKAC VWLV

Frame 1

HSVIFIEHLLCSRHCPRH*G*SSEVNRKKSLPS WSLIF*HETIMDRKNICSMLDLER*YGAKIK*G RGIGGVGDA*NFRLAWPGKPHPVPGHHR*AHSPC HSDLCPWKMHQVHG*VAGSCLWGALSNTNKNLR AWAWLSGMVLTWGWFLGLGCSRGSLEAGSGLAA RKPCTRANRPRASCLLLVTLRPHMSVFLTGKLKI PSPWIGQW*VV*IFCAKSPEGPLP*PCRGQMVQ GRMGTGRGNGSLGCAEQSLLGTANPTLAWPEVI GLKHRGPLRQFRGWEIWKRVLERRSNLNNRREQG HRKG*QEPQRTLDSETG*HWISHIEKRK*AGAG PGVDTWILHLPAG*PGQFL*SLSLSFLLSKTGM IMCLARLL*GFINEVMYVKCLAQHGHSNRGAFSH FTPYKVLFTCVIAILARLLRGRWGYNPWCSRKE AEAQWG*MTSLSSQSSVSGRVGTHIQTL*LQT* VFPHLHAEASPRQ*EAQSPKHRVLCVGLCVLRSL VTALGLWAVVS*QSFVLCGDDVGQWEDKCPSEL SSGQ*QSWS*S*P*ASARSPSAF*MTTGDWF*W *VCGDLFWSSGCWSSVCSIDQDLQTQKLMGAGTS PHHLRFGQSKQQQGAGCGPGVRGGQRQNKP**A KAVPTATAWQL*SGK*GTATIPEHFQADSRR*H GDLCR*AQEGP*HSREQTQGPEDTRVHTGVLP*H DCAHGYRWLWKAQPAGVPPPLEQD*GLAENFQT L*HRPVRHHQQLRDAKCSQRRRIPPQQPAL*HH YHAVRRQTHEHRL*QFHLLLR*AGGHVQSFSCI* QGWRWYHQAQRSGVAAAHHVCLNQAGLIQSHAG SLRISVSPSISKAIYLKGPSSYTPTGFQAPHQS CSSSILPPTHP*SVMPSLTL**SNEVGRTNPCPF AMWRKVPASGPSRLGSEASAPAYLALGCLQKHL PVALSTSLC*SPPSPSRCPTMGQEPNQHWVLLL WGKLTQWNRAGYFGLSNS*VWLHFEKS*SK*RHV YGW

Frame 2

IL*YLLSTYYVPGTVLGTKDRVVK*TERNPCLH GA*YSNMRQ*WIGKTYVAC*IWRGDMEQK*SRE EG*EVLGMLEILG*HGQESHILSLATTDELIAP ATLISVLGRCTRSMGRWLGHAFGGL*AILTRTCV PGLGCRGWC*HGAGSWGWGVPGVL*RLVLAWLP GSRAPEQTVHGPPACFW*H*DPTCLYSSQGS*K YHLRGSASGEWFRSSVRKVQRVPFPDHAGDRWCR GEWALAEGMGVWAVLSSPSLALQILLWHGQK*S ALSTGGH*GSSGAGKYGRGSWKGEAI*TIGGNK ATGRDDKSRSEHWILRLDNIGFHT*RKESKLVPD LVLTLGSSTYQRGDLDNFCNPSHSVSYSVKRG* *CALQGFCEASSMR*CM*SVWHSMGTQTEVLFH TLHLTRYFSHVSSRYLQGC*EVDGVIIPGVQERK QRLNGVE*LL*VHRAQ*VAGLELTFRLSDSRLR FFRTSTLRPAPGSEKPKVRSTECCVLGSVC*GV L*LPWGFGL*SADSPLCSVGMT*ANGRTNAPLNC LLGSDSHGHNPDPEPVPGLQVPSE*PQAIGFSG RCVGICSGHLDAGHRCAVLIRTCKPKSLWELAR HPIIFVSDRANSNKELGVDQESEEGKGKTSPDKQ KQSPQPQPGSSDQESEEQQQFRNIFKQIAGDDM EICADELKKVLNTVVNKHKDLKTHGFTLESCRS MIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKH YDTDQSGTINSYEMRNAVNDAGFHLNNQLYDII TMRYADKHMNIDFDSFICCFVRLEGMFRAFHAF DKDGDGIIKLNVLEWLQLTMYA*TRLASSKAMQD HSGFQFHPLFPKPFTSKDPAATPLQASRHLISH APPPFYPLPILDRSCLA*PFSKAMR*EEQTLVP LPCGGKCLPLVRAASVLKRVLLLTLL*AVCRSTC RWHSAPPCARALHHLHAVPPWARNQTSTGFYCC GVN*LSGIGLVTLGCPTHKFGCILKKADLNKGM CMAG