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Sequences

Sequence CASP9.dAug05

GACGCAGTGGTGGATTCTGGAGCGGGGCGGTGACGTGGGGCGGGTTCTGGGGCGGGGCGGTGACGCGGAGCGTGTTCTGGGGCGGCGCGGTGATGGGAGG
CTTGGCCCTGGGGGCGGGGCGAGGCGCAGAGGTGCGTCCTGAGGGCGGGGCGGTGACGCAAGAGCGACTCCTGGGGGCGGGGCGAGGCCTTGGAGATGCG
TCCGGAGGCGGTGGGGAGCGAAGACTGACCCGGGGCCGTGACGCGGGGGCAGGCCCTGGGGCGGGGGCGGGTCCTGGGGACTGGGGCGGGCGGCCGAGGC
CCGGAAGCGGACTGAGGCGGCCTGGAGTCTTAGTTGGCTACTCGCCATGGACGAAGCGGATCGGCGGCTCCTGCGGCGGTGCCGGCTGCGGCTGGTGGAA
GAGCTGCAGGTGGACCAGCTCTGGGACGCCCTGCTGAGCCGCGAGCTGTTCAGGCCCCATATGATCGAGGACATCCAGCGGGCAGGCTCTGGATCTCGGC
GGGATCAGGCCAGGCAGCTGATCATAGATCTGGAGACTCGAGGGAGTCAGGCTCTTCCTTTGTTCATCTCCTGCTTAGAGGACACAGGCCAGGACATGCT
GGCTTCGTTTCTGCGAACTAACAGGCAAGCAGCAAAGTTGTCGAAGCCAACCCTAGAAAACCTTACCCCAGTGGTGCTCAGACCAGAGATTCGCAAACCA
GAGGTTCTCAGACCGGAAACACCCAGACCAGTGGACATTGGTTCTGGAGGATTTGGTGATGTCG
AGCAGAAAGACCATGGGTTTGAGGTGGCCTCCACTT
CCCCTGAAGACGAGTCCCCTGGCAGTAACCCCGAGCCAGATGCCACCCCGTTCCAGGAAGGTTTGAGGACCTTCGACCAGCTGGACGCCATATCTAGTTT
GCCCACACCCAGTGACATCTTTGTGTCCTACTCTACTTTCCCAGGTTTTGTTTCCTGGAGGGACCCCAAGAGTGGCTCCTGGTACGTTGAGACCCTGGAC
GACATCTTTGAGCAGTGGGCTCACTCTGAAGACCTGCAGTCCCTCCTGCTTAGGGTCGCTAATGCTGTTTCGGTGAAAGGGATTTATAAACAGATGCCTG
GTTGCTTTAATTTCCTCCGGAAAAAACTTTTCTTTAAAACATCATAAGGCCAGGGCCCCTCACCCTGCCTTATCTTGCACCCCAAAGCTTTCCTGCCCCA
GGCCTGAAAGAGGCTGAGGCCTGGACTTTCCTGCAACTCAAGGACTTTGCAGCCGGCACAGGGTCTGCTCTTTCTCTGCCAGTGACAGACAGGCTCTTAG
CAGCTTCCAGATTGACGACAAGTGCTGAACAGTGGAGGAAGAGGGACAGATGAATGCCGTGGATTGCACGTGGCCTCTTGAGCAGTGGCTGGTCCAGGGC
TAGTGACTTGTGTCCCATGATCCCTGTGTTGTCTCTAGAGCAGGGATTAACCTCTGCACTACTGACATGTGGGGCCAGGTCACCCTTTGCTGTGAGGCTG
TCCTGTACATTGTGGGATGTTCAGCACTGTCCCTTGCCTCAATGCCAGTAACGCGTCTTCCTGAGTGGTGCCAAACAAAAAGGTTCTCAGGTGTTGCCAA
ATATGTCCTGGGGTATAAAACTTTCCTCGCCTGACAACCACTGGTCTGTAGGGATTTTTGGCTACACACAAACCAGTATCGCTCATAGATCAGCAAACCG
GGGCCTACTAGAGTCTGAACAGCTGTAATCTATGAATTCTAAGTGAAATTTTAAAAATTGTTAATTTTTCCTATATTGCATTAATTTTAAAAAATAAATC
TGAGGCAAATATGGACTCTCT
  • primer-113212 (forward primer)
  • primer-113213 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

DAVVDSGAGR*RGAGSGAGR*RGACSGAAR*WE
AWPWGRGEAQRCVLRAGR*RKSDSWGRGEALEMR
PEAVGSED*PGAVTRGQALGRGRVLGTGAGGRG
PEAD*GGLES*LATRHGRSGSAAPAAVPAAAGG
RAAGGPALGRPAEPRAVQAPYDRGHPAGRLWISA
GSGQAADHRSGDSRESGSSFVHLLLRGHRPGHA
GFVSAN*QASSKVVEANPRKPYPSGAQTRDSQT
RGSQTGNTQTSGHWFWRIW*CR
AERPWV*GGLHF
P*RRVPWQ*PRARCHPVPGRFEDLRPAGRHI*F
AHTQ*HLCVLLYFPRFCFLEGPQEWLLVR*DPG
RHL*AVGSL*RPAVPPA*GR*CCFGERDL*TDAW
LL*FPPEKTFL*NIIRPGPLTLPYLAPQSFPAP
GLKEAEAWTFLQLKDFAAGTGSALSLPVTDRLL
AASRLTTSAEQWRKRDR*MPWIARGLLSSGWSRA
SDLCPMIPVLSLEQGLTSALLTCGARSPFAVRL
SCTLWDVQHCPLPQCQ*RVFLSGAKQKGSQVLP
NMSWGIKLSSPDNHWSVGIFGYTQTSIAHRSANR
GLLESEQL*SMNSK*NFKNC*FFLYCINFKK*I
*GKYGLS

Frame 1

TQWWILERGGDVGRVLGRGGDAERVLGRRGDGR
LGPGGGARRRGAS*GRGGDARATPGGGARPWRC
VRRRWGAKTDPGP*RGGRPWGGGGSWGLGRAAEA
RKRTEAAWSLSWLLAMDEADRRLLRRCRLRLVE
ELQVDQLWDALLSRELFRPHMIEDIQRAGSGSR
RDQARQLIIDLETRGSQALPLFISCLEDTGQDML
ASFLRTNRQAAKLSKPTLENLTPVVLRPEIRKP
EVLRPETPRPVDIGSGGFGDV
EQKDHGFEVAST
SPEDESPGSNPEPDATPFQEGLRTFDQLDAISSL
PTPSDIFVSYSTFPGFVSWRDPKSGSWYVETLD
DIFEQWAHSEDLQSLLLRVANAVSVKGIYKQMP
GCFNFLRKKLFFKTS*GQGPSPCLILHPKAFLPQ
A*KRLRPGLSCNSRTLQPAQGLLFLCQ*QTGS*
QLPD*RQVLNSGGRGTDECRGLHVAS*AVAGPG
LVTCVP*SLCCL*SRD*PLHY*HVGPGHPLL*GC
PVHCGMFSTVPCLNASNASS*VVPNKKVLRCCQ
ICPGV*NFPRLTTTGL*GFLATHKPVSLIDQQT
GAY*SLNSCNL*ILSEILKIVNFSYIALILKNKS
EANMDS

Frame 2

RSGGFWSGAVTWGGFWGGAVTRSVFWGGAVMGG
LALGAGRGAEVRPEGGAVTQERLLGAGRGLGDA
SGGGGERRLTRGRDAGAGPGAGAGPGDWGGRPR
PGSGLRRPGVLVGYSPWTKRIGGSCGGAGCGWWK
SCRWTSSGTPC*AASCSGPI*SRTSSGQALDLG
GIRPGS*S*IWRLEGVRLFLCSSPA*RTQARTC
WLRFCELTGKQQSCRSQP*KTLPQWCSDQRFANQ
RFSDRKHPDQWTLVLEDLVMS
SRKTMGLRWPPL
PLKTSPLAVTPSQMPPRSRKV*GPSTSWTPYLV
CPHPVTSLCPTLLSQVLFPGGTPRVAPGTLRPWT
TSLSSGLTLKTCSPSCLGSLMLFR*KGFINRCL
VALISSGKNFSLKHHKARAPHPALSCTPKLSCP
RPERG*GLDFPATQGLCSRHRVCSFSASDRQALS
SFQIDDKC*TVEEEGQMNAVDCTWPLEQWLVQG
**LVSHDPCVVSRAGINLCTTDMWGQVTLCCEA
VLYIVGCSALSLASMPVTRLPEWCQTKRFSGVAK
YVLGYKTFLA*QPLVCRDFWLHTNQYRS*ISKP
GPTRV*TAVIYEF*VKF*KLLIFPILH*F*KIN
LRQIWTL

Sequence CASP9.eAug05

GACGCAGTGGTGGATTCTGGAGCGGGGCGGTGACGTGGGGCGGGTTCTGGGGCGGGGCGGTGACGCGGAGCGTGTTCTGGGGCGGCGCGGTGATGGGAGG
CTTGGCCCTGGGGGCGGGGCGAGGCGCAGAGGTGCGTCCTGAGGGCGGGGCGGTGACGCAAGAGCGACTCCTGGGGGCGGGGCGAGGCCTTGGAGATGCG
TCCGGAGGCGGTGGGGAGCGAAGACTGACCCGGGGCCGTGACGCGGGGGCAGGCCCTGGGGCGGGGGCGGGTCCTGGGGACTGGGGCGGGCGGCCGAGGC
CCGGAAGCGGACTGAGGCGGCCTGGAGTCTTAGTTGGCTACTCGCCATGGACGAAGCGGATCGGCGGCTCCTGCGGCGGTGCCGGCTGCGGCTGGTGGAA
GAGCTGCAGGTGGACCAGCTCTGGGACGCCCTGCTGAGCCGCGAGCTGTTCAGGCCCCATATGATCGAGGACATCCAGCGGGCAGGCTCTGGATCTCGGC
GGGATCAGGCCAGGCAGCTGATCATAGATCTGGAGACTCGAGGGAGTCAGGCTCTTCCTTTGTTCATCTCCTGCTTAGAGGACACAGGCCAGGACATGCT
GGCTTCGTTTCTGCGAACTAACAGGTGCTCTTGAGAGTTTGAGGGGAAATGCAGATTTGGCTTACATCCTGAGCATGGAGCCCTGTGGCCACTGCCTCAT
TATCAACAATGTGAACTTCTGCCGTGAGTCCGGGCTCCGCACCCGCACTGGCTCCAACATCGACTGTGAGAAGTTGCGGCGTCGCTTCTCCTCGCTGCAT
TTCATGGTGGAGGTGAAGGGCGACCTGACTGCCAAGAAAATGGTGCTGGCTTTGCTGGAGCTGGCGCAGCAGGACCACGGTGCTCTGGACTGCTGCGTGG
TGGTCATTCTCTCTCACGGCTGTCAGGCCAGCCACCTGCAGTTCCCAGGGGCTGTCTACGGCACAGATGGATGCCCTGTGTCGGTCGAGAAGATTGTGAA
CATCTTCAATGGGACCAGCTGCCCCAGCCTGGGAGGGAAGCCCAAGCTCTTTTTCATCCAGGCCTGTGGTGGGG
AGCAGAAAGACCATGGGTTTGAGGTG
GCCTCCACTTCCCCTGAAGACGAGTCCCCTGGCAGTAACCCCGAGCCAGATGCCACCCCGTTCCAGGAAGGTTTGAGGACCTTCGACCAGCTGGACGCCA
TATCTAGTTTGCCCACACCCAGTGACATCTTTGTGTCCTACTCTACTTTCCCAGGTTTTGTTTCCTGGAGGGACCCCAAGAGTGGCTCCTGGTACGTTGA
GACCCTGGACGACATCTTTGAGCAGTGGGCTCACTCTGAAGACCTGCAGTCCCTCCTGCTTAGGGTCGCTAATGCTGTTTCGGTGAAAGGGATTTATAAA
CAGATGCCTGGTTGCTTTAATTTCCTCCGGAAAAAACTTTTCTTTAAAACATCATAAGGCCAGGGCCCCTCACCCTGCCTTATCTTGCACCCCAAAGCTT
TCCTGCCCCAGGCCTGAAAGAGGCTGAGGCCTGGACTTTCCTGCAACTCAAGGACTTTGCAGCCGGCACAGGGTCTGCTCTTTCTCTGCCAGTGACAGAC
AGGCTCTTAGCAGCTTCCAGATTGACGACAAGTGCTGAACAGTGGAGGAAGAGGGACAGATGAATGCCGTGGATTGCACGTGGCCTCTTGAGCAGTGGCT
GGTCCAGGGCTAGTGACTTGTGTCCCATGATCCCTGTGTTGTCTCTAGAGCAGGGATTAACCTCTGCACTACTGACATGTGGGGCCAGGTCACCCTTTGC
TGTGAGGCTGTCCTGTACATTGTGGGATGTTCAGCACTGTCCCTTGCCTCAATGCCAGTAACGCGTCTTCCTGAGTGGTGCCAAACAAAAAGGTTCTCAG
GTGTTGCCAAATATGTCCTGGGGTATAAAACTTTCCTCGCCTGACAACCACTGGTCTGTAGGGATTTTTGGCTACACACAAACCAGTATCGCTCATAGAT
CAGCAAACCGGGGCCTACTAGAGTCTGAACAGCTGTAATCTATGAATTCTAAGTGAAATTTTAAAAATTGTTAATTTTTCCTATATTGCATTAATTTTAA
AAAATAAATCTGAGGCAAATATGGACTCTCT
  • primer-113212 (forward primer)
  • primer-113213 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

DAVVDSGAGR*RGAGSGAGR*RGACSGAAR*WE
AWPWGRGEAQRCVLRAGR*RKSDSWGRGEALEMR
PEAVGSED*PGAVTRGQALGRGRVLGTGAGGRG
PEAD*GGLES*LATRHGRSGSAAPAAVPAAAGG
RAAGGPALGRPAEPRAVQAPYDRGHPAGRLWISA
GSGQAADHRSGDSRESGSSFVHLLLRGHRPGHA
GFVSAN*QVLLRV*GEMQIWLTS*AWSPVATAS
LSTM*TSAVSPGSAPALAPTSTVRSCGVASPRCI
SWWR*RAT*LPRKWCWLCWSWRSRTTVLWTAAW
WSFSLTAVRPATCSSQGLSTAQMDALCRSRRL*
TSSMGPAAPAWEGSPSSFSSRPVVG
SRKTMGLRW
PPLPLKTSPLAVTPSQMPPRSRKV*GPSTSWTP
YLVCPHPVTSLCPTLLSQVLFPGGTPRVAPGTL
RPWTTSLSSGLTLKTCSPSCLGSLMLFR*KGFIN
RCLVALISSGKNFSLKHHKARAPHPALSCTPKL
SCPRPERG*GLDFPATQGLCSRHRVCSFSASDR
QALSSFQIDDKC*TVEEEGQMNAVDCTWPLEQWL
VQG**LVSHDPCVVSRAGINLCTTDMWGQVTLC
CEAVLYIVGCSALSLASMPVTRLPEWCQTKRFS
GVAKYVLGYKTFLA*QPLVCRDFWLHTNQYRS*I
SKPGPTRV*TAVIYEF*VKF*KLLIFPILH*F*
KINLRQIWTL

Frame 1

TQWWILERGGDVGRVLGRGGDAERVLGRRGDGR
LGPGGGARRRGAS*GRGGDARATPGGGARPWRC
VRRRWGAKTDPGP*RGGRPWGGGGSWGLGRAAEA
RKRTEAAWSLSWLLAMDEADRRLLRRCRLRLVE
ELQVDQLWDALLSRELFRPHMIEDIQRAGSGSR
RDQARQLIIDLETRGSQALPLFISCLEDTGQDML
ASFLRTNRCS*EFEGKCRFGLHPEHGALWPLPH
YQQCELLP*VRAPHPHWLQHRL*EVAASLLLAA
FHGGGEGRPDCQENGAGFAGAGAAGPRCSGLLRG
GHSLSRLSGQPPAVPRGCLRHRWMPCVGREDCE
HLQWDQLPQPGREAQALFHPGLWWG
AERPWV*G
GLHFP*RRVPWQ*PRARCHPVPGRFEDLRPAGRH
I*FAHTQ*HLCVLLYFPRFCFLEGPQEWLLVR*
DPGRHL*AVGSL*RPAVPPA*GR*CCFGERDL*
TDAWLL*FPPEKTFL*NIIRPGPLTLPYLAPQSF
PAPGLKEAEAWTFLQLKDFAAGTGSALSLPVTD
RLLAASRLTTSAEQWRKRDR*MPWIARGLLSSG
WSRASDLCPMIPVLSLEQGLTSALLTCGARSPFA
VRLSCTLWDVQHCPLPQCQ*RVFLSGAKQKGSQ
VLPNMSWGIKLSSPDNHWSVGIFGYTQTSIAHR
SANRGLLESEQL*SMNSK*NFKNC*FFLYCINFK
K*I*GKYGLS

Frame 2

RSGGFWSGAVTWGGFWGGAVTRSVFWGGAVMGG
LALGAGRGAEVRPEGGAVTQERLLGAGRGLGDA
SGGGGERRLTRGRDAGAGPGAGAGPGDWGGRPR
PGSGLRRPGVLVGYSPWTKRIGGSCGGAGCGWWK
SCRWTSSGTPC*AASCSGPI*SRTSSGQALDLG
GIRPGS*S*IWRLEGVRLFLCSSPA*RTQARTC
WLRFCELTGALESLRGNADLAYILSMEPCGHCLI
INNVNFCRESGLRTRTGSNIDCEKLRRRFSSLH
FMVEVKGDLTAKKMVLALLELAQQDHGALDCCV
VVILSHGCQASHLQFPGAVYGTDGCPVSVEKIVN
IFNGTSCPSLGGKPKLFFIQACGG
EQKDHGFEV
ASTSPEDESPGSNPEPDATPFQEGLRTFDQLDA
ISSLPTPSDIFVSYSTFPGFVSWRDPKSGSWYVE
TLDDIFEQWAHSEDLQSLLLRVANAVSVKGIYK
QMPGCFNFLRKKLFFKTS*GQGPSPCLILHPKA
FLPQA*KRLRPGLSCNSRTLQPAQGLLFLCQ*QT
GS*QLPD*RQVLNSGGRGTDECRGLHVAS*AVA
GPGLVTCVP*SLCCL*SRD*PLHY*HVGPGHPL
L*GCPVHCGMFSTVPCLNASNASS*VVPNKKVLR
CCQICPGV*NFPRLTTTGL*GFLATHKPVSLID
QQTGAY*SLNSCNL*ILSEILKIVNFSYIALIL
KNKSEANMDS

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