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Sequences

Sequence TNFSF13.gAug05

CCGGAACCCTGTGTGCTGGGGAGGAATCCCGCAGTGGCCGGGGGGCTTGAGGCCGCTGCTTTGTCTCTTCGTCCAGAGCCTTATGTAAGAGCTTTTCTCG GGAAACAGGAAGTCCTGCTTGCCAATTTCAGCACAGGGAGTAGTGCAGGCCTTATTCCAACACACCCGGCCCAGCCTTAACCCCAGAACTCAGCCAGTTT CTTGCTTCCGTGCCCCTGGTTCTCCTCCCCATCGAGCCCACCCCTCCTTTCCCACCTTCAGTCACCCCTAGTGAACTGCCCCAGCGATCTCTGCTGTGCT TGACCCCGAGGGTCTTCCACCCTCGCCCTGACCCTGGACACTGCCCAGCTTGGCCCCCCATCCTGCTCCTGGCACAATGCCCTCTAGCCAGCCAACCTTC CCTCCCCCAACCCTGGGGCCGCCCCAGGGTTCCTGCGCACTGCCTGTTCCTCCTGGGTGTCACTGGCAGCCCTGTCCTTCCTAGAGGGACTGGAACCTAA TTCTCCTGAGGCTGAGGGAGGGTGGAGGGTCTCAAGGCAACGCTGGCCCCACGACGGAGTGCCAGGAGCACTAACAGTACCCTTAGCTTGCTTTCCTCCT CCCTCCTTTTTATTTTCAAGTTCCTTTTTATTTCTCCTTGCGTAACAACCTTCTTCCCTTCTGCACCACTGCCCGTACCCTTACCCGCCCCGCCACCTCC TTGCTACCCCACTCTTGAAACCACAGCTGTTGGCAGGGTCCCCAGCTCATGCCAGCCTCATCTCCTTTCTTGCTAGCCCCCAAAGGGCCTCCAGGCAACA TGGGGGGCCCAGTCAGAGAGCCGGCACTCTCAGTTGCCCTCTGGTTGAGTTGGGGGGCAGCTCTGGGGGCCGTGGCTTGTGCCATGGCTCTGCTGACCCA ACAAACAGAGCTGCAGAGCCTCAGGAGAGAGGTGAGCCGGCTGCAGGGGACAGGAGGCCCCTCCCAGAATGGGGAAGGGTATCCCTGGCAGAGTCTCCCG GAGCAGAGTTCCGATGCCCTGGAAGCCTGGGAGAATGGGGAGAGATCCCGGAAAAGGAGAGCAGTGCTCACCCAAAAACAGAAGAATGACTCCGATGTGA CAGAGGTGATGTGGCAACCAGCTCTTAGGCGTGGGAGAGGCCTACAGGCCCAAGGATATGGTGTCCGAATCCAGGATGCTGGAGTTTATCTGCTGTATAG CCAGGTCCTGTTTCAAGACGTGACTTTCACCATGGGTCAGGTGGTGTCTCGAGAAGGCCAAGGAAGGCAGGAGACTCTATTCCGATGTATAAGAAGTATG CCCTCCCACCCGGACCGGGCCTACAACAGCTGCTATAGCGCAGGTGTCTTCCATTTACACCAAGGGGATATTCTGAGTGTCATAATTCCCCGGGCAAGGG CGAAACTTAACCTCTCTCCACATGGAACCTTCCTGGGGTTTGTGAAACTGTGATTGTGTTATAAAAAGTGGCTCCCAGCTTGGAAGACCAGGGTGGGTAC ATACTGGAGACAGCCAAGAGCTGAGTATATAAAGGAGAGGGAATGTGCAGGAACAGAGGCGTCTTCCTGGGTTTGGCTCCCCGTTCCTCACTTTTCCCTT TTCATTCCCACCCCCTAGACTTTGATTTTACGGATATCTTGCTTCTGTTCCCCATGGAGCTCCGAATTCTTGCGTGTGTGTAGATGAGGGGCGGGGGACG GGCGCCAGGCATTGTCCAGACCTGGTCGGGGCCCACTGGAAGCATCCAGAACAGCACCACCATCTAGCGGCCGCTCGAGGGAAGCACCCGCCGGTTGGCC GAAGTCCACGAAGCCGCCCTCTGCTAGGGAAAACCCCTGGTTCTCCATGCCACACCTCTCTCCAGGTGCCCTCTGCCTCTTCACCCCACAAGAAGCCTTA TCCTACGTCCTTCTCTCCATCTATCGGACCCCAGTTTCCATCACTATCTCCAGAGATGTAGCTATTATGCGCCCGTCTACAGGGGGTGCCCGACGATGAC GGTGCCTTCGCAGTCAAATTACTCTTCGGGTCCCAAGGTTTGGCTTTCACGCGCTCCATTGCCCCGGCGTGGCAGGCCATTCCAAGCCCTTCCGGGCTGG AACTGGTGTCGGAGGAGCCTCGGGTGTATCGTACGCCCTGGTGTTGGTGTTGCCTCACTCCTCTGAGCTCTTCTTTCTGATCAAGCCCTGCTTAAAGTTA AATAAAATAGAATGAATGATACCCCGGC

primer-113239 (forward primer)
primer-113220 (reverse primer)
Single exon skipping

Frame 0

PEPCVLGRNPAVAGGLEAAALSLRPEPYVRAFL GKQEVLLANFSTGSSAGLIPTHPAQP*PQNSASF LLPCPWFSSPSSPPLLSHLQSPLVNCPSDLCCA *PRGSSTLALTLDTAQLGPPSCSWHNAL*PANL PSPNPGAAPGFLRTACSSWVSLAALSFLEGLEPN SPEAEGGWRVSRQRWPHDGVPGALTVPLACFPP PSFLFSSSFLFLLA*QPSSLLHHCPYPYPPRHL LATPLLKPQLLAGSPAHASLISFLASPQRASRQH GGPSQRAGTLSCPLVELGGSSGGRGLCHGSADP TNRAAEPQERGEPAAGDRRPLPEWGRVSLAESP GAEFRCPGSLGEWGEIPEKESSAHPKTEE*LRCD RGDVATSS*AWERPTGPRIWCPNPGCWSLSAV* PGPVSRRDFHHGSGGVSRRPRKAGDSIPMYKKY ALPPGPGLQQLL*RRCLPFTPRGYSECHNSPGKG ET*PLSTWNLPGVCETVIVL*KVAPSLEDQGGY ILETAKS*VYKGEGMCRNRGVFLGLAPRSSLFP FHSHPLDFDFTDILLLFPMELRILACV*MRGGGR APGIVQTWSGPTGSIQNSTTI*RPLEGSTRRLA EVHEAALC*GKPLVLHATPLSRCPLPLHPTRSL ILRPSLHLSDPSFHHYLQRCSYYAPVYRGCPTMT VPSQSNYSSGPKVWLSRAPLPRRGRPFQALPGW NWCRRSLGCIVRPGVGVASLL*ALLSDQALLKV K*NRMNDTP

Frame 1

RNPVCWGGIPQWPGGLRPLLCLFVQSLM*ELFS GNRKSCLPISAQGVVQALFQHTRPSLNPRTQPV SCFRAPGSPPHRAHPSFPTFSHP**TAPAISAVL DPEGLPPSP*PWTLPSLAPHPAPGTMPSSQPTF PPPTLGPPQGSCALPVPPGCHWQPCPS*RDWNL ILLRLREGGGSQGNAGPTTECQEH*QYP*LAFLL PPFYFQVPFYFSLRNNLLPFCTTARTLTRPATS LLPHS*NHSCWQGPQLMPASSPFLLAPKGPPGN MGGPVREPALSVALWLSWGAALGAVACAMALLTQ QTELQSLRREVSRLQGTGGPSQNGEGYPWQSLP EQSSDALEAWENGERSRKRRAVLTQKQKNDSDV TEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLYS QVLFQDVTFTMGQVVSREGQGRQETLFRCIRSM PSHPDRAYNSCYSAGVFHLHQGDILSVIIPRAR AKLNLSPHGTFLGFVKL*LCYKKWLPAWKTRVGT YWRQPRAEYIKERECAGTEASSWVWLPVPHFSL FIPTP*TLILRISCFCSPWSSEFLRVCR*GAGD GRQALSRPGRGPLEASRTAPPSSGRSREAPAGWP KSTKPPSARENPWFSMPHLSPGALCLFTPQEAL SYVLLSIYRTPVSITISRDVAIMRPSTGGARR* RCLRSQITLRVPRFGFHALHCPGVAGHSKPFRAG TGVGGASGVSYALVLVLPHSSELFFLIKPCLKL NKIE*MIPR

Frame 2

GTLCAGEESRSGRGA*GRCFVSSSRALCKSFSR ETGSPACQFQHRE*CRPYSNTPGPALTPELSQF LASVPLVLLPIEPTPPFPPSVTPSELPQRSLLC LTPRVFHPRPDPGHCPAWPPILLLAQCPLASQPS LPQPWGRPRVPAHCLFLLGVTGSPVLPRGTGT* FS*G*GRVEGLKATLAPRRSARSTNSTLSLLSS SLLFIFKFLFISPCVTTFFPSAPLPVPLPAPPPP CYPTLETTAVGRVPSSCQPHLLSC*PPKGLQAT WGAQSESRHSQLPSG*VGGQLWGPWLVPWLC*P NKQSCRASGER*AGCRGQEAPPRMGKGIPGRVSR SRVPMPWKPGRMGRDPGKGEQCSPKNRRMTPM* QR*CGNQLLGVGEAYRPKDMVSESRMLEFICCI ARSCFKT*LSPWVRWCLEKAKEGRRLYSDV*EVC PPTRTGPTTAAIAQVSSIYTKGIF*VS*FPGQG RNLTSLHMEPSWGL*NCDCVIKSGSQLGRPGWV HTGDSQELSI*RRGNVQEQRRLPGFGSPFLTFPF SFPPPRL*FYGYLASVPHGAPNSCVCVDEGRGT GARHCPDLVGAHWKHPEQHHHLAAARGKHPPVG RSPRSRPLLGKTPGSPCHTSLQVPSASSPHKKPY PTSFSPSIGPQFPSLSPEM*LLCARLQGVPDDD GAFAVKLLFGSQGLAFTRSIAPAWQAIPSPSGL ELVSEEPRVYRTPWCWCCLTPLSSSF*SSPA*S* IK*NE*YPG

Sequence TNFSF13.hAug05

primer-113239 (forward primer)
primer-113220 (reverse primer)
Single exon skipping

Frame 0

LGHSAGAGTGPGWEVGRAGASLEEGLRVSRHTG TRNPVCWGGIPQWPGGLRPLLCLFVQSLIPQRAS RQHGGPSQRAGTLSCPLVELGGSSGGRGLCHGS ADPTNRAAEPQERGEPAAGDRRPLPEWGRVSLA ESPGAEFRCPGSLGEWGEIPEKESSAHPKTEEAA LCPAPGSH*RHLQG*LRCDRGDVATSS*AWERP TGPRIWCPNPGCWSLSAV*PGPVSRRDFHHGSG GVSRRPRKAGDSIPMYKKYALPPGPGLQQLL*RR L*FYGYLASVPHGAPNSCVCVDEGRGTGARHCP DLVGAHWKHPEQHHHLAAARGKHPPVGRSPRSR PLLGKTPGSPCHTSLQVPSASSPHKKPYPTSFSP SIGPQFPSLSPEM*LLCARLQGVPDDDGAFAVK LLFGSQGLAFTRSIAPAWQAIPSPSGLELVSEE PRVYRTPWCWCCLTPLSSSF*SSPA*S*IK*NE* YPG

Frame 1

SDIQQVLAQALAGRWGGQEPAWRRG*ESAGTRE PGTLCAGEESRSGRGA*GRCFVSSSRALSPKGP PGNMGGPVREPALSVALWLSWGAALGAVACAMAL LTQQTELQSLRREVSRLQGTGGPSQNGEGYPWQ SLPEQSSDALEAWENGERSRKRRAVLTQKQKKQ HSVLHLVPINATSKDDSDVTEVMWQPALRRGRGL QAQGYGVRIQDAGVYLLYSQVLFQDVTFTMGQV VSREGQGRQETLFRCIRSMPSHPDRAYNSCYSA DFDFTDILLLFPMELRILACV*MRGGGRAPGIVQ TWSGPTGSIQNSTTI*RPLEGSTRRLAEVHEAA LC*GKPLVLHATPLSRCPLPLHPTRSLILRPSL HLSDPSFHHYLQRCSYYAPVYRGCPTMTVPSQSN YSSGPKVWLSRAPLPRRGRPFQALPGWNWCRRS LGCIVRPGVGVASLL*ALLSDQALLKVK*NRMN DTP

Frame 2

RTFSRCWHRPWLGGGAGRSQPGGGAESQQAHGN PEPCVLGRNPAVAGGLEAAALSLRPEPYPPKGL QATWGAQSESRHSQLPSG*VGGQLWGPWLVPWL C*PNKQSCRASGER*AGCRGQEAPPRMGKGIPGR VSRSRVPMPWKPGRMGRDPGKGEQCSPKNRRSS TLSCTWFPLTPPPRMTPM*QR*CGNQLLGVGEA YRPKDMVSESRMLEFICCIARSCFKT*LSPWVRW CLEKAKEGRRLYSDV*EVCPPTRTGPTTAAIAQ TLILRISCFCSPWSSEFLRVCR*GAGDGRQALS RPGRGPLEASRTAPPSSGRSREAPAGWPKSTKPP SARENPWFSMPHLSPGALCLFTPQEALSYVLLS IYRTPVSITISRDVAIMRPSTGGARR*RCLRSQ ITLRVPRFGFHALHCPGVAGHSKPFRAGTGVGGA SGVSYALVLVLPHSSELFFLIKPCLKLNKIE*M IPR

Sequence TNFSF13.fAug05

CCGGAACCCTGTGTGCTGGGGAGGAATCCCGCAGTGGCCGGGGGGCTTGAGGCCGCTGCTTTGTCTCTTCGTCCAGAGCCTTATGTAAGAGCTTTTCTCG GGAAACAGGAAGTCCTGCTTGCCAATTTCAGCACAGGGAGTAGTGCAGGCCTTATTCCAACACACCCGGCCCAGCCTTAACCCCAGAACTCAGCCAGTTT CTTGCTTCCGTGCCCCTGGTTCTCCTCCCCATCGAGCCCACCCCTCCTTTCCCACCTTCAGTCACCCCTAGTGAACTGCCCCAGCGATCTCTGCTGTGCT TGACCCCGAGGGTCTTCCACCCTCGCCCTGACCCTGGACACTGCCCAGCTTGGCCCCCCATCCTGCTCCTGGCACAATGCCCTCTAGCCAGCCAACCTTC CCTCCCCCAACCCTGGGGCCGCCCCAGGGTTCCTGCGCACTGCCTGTTCCTCCTGGGTGTCACTGGCAGCCCTGTCCTTCCTAGAGGGACTGGAACCTAA TTCTCCTGAGGCTGAGGGAGGGTGGAGGGTCTCAAGGCAACGCTGGCCCCACGACGGAGTGCCAGGAGCACTAACAGTACCCTTAGCTTGCTTTCCTCCT CCCTCCTTTTTATTTTCAAGTTCCTTTTTATTTCTCCTTGCGTAACAACCTTCTTCCCTTCTGCACCACTGCCCGTACCCTTACCCGCCCCGCCACCTCC TTGCTACCCCACTCTTGAAACCACAGCTGTTGGCAGGGTCCCCAGCTCATGCCAGCCTCATCTCCTTTCTTGCTAGCCCCCAAAGGGCCTCCAGGCAACA TGGGGGGCCCAGTCAGAGAGCCGGCACTCTCAGTTGCCCTCTGGTTGAGTTGGGGGGCAGCTCTGGGGGCCGTGGCTTGTGCCATGGCTCTGCTGACCCA ACAAACAGAGCTGCAGAGCCTCAGGAGAGAGGTGAGCCGGCTGCAGGGGACAGGAGGCCCCTCCCAGAATGGGGAAGGGTATCCCTGGCAGAGTCTCCCG GAGCAGAGTTCCGATGCCCTGGAAGCCTGGGAGAATGGGGAGAGATCCCGGAAAAGGAGAGCAGTGCTCACCCAAAAACAGAAGAAGCAGCACTCTGTCC TGCACCTGGTTCCCATTAACGCCACCTCCAAGGATGACTCCGATGTGACAGAGGTGATGTGGCAACCAGCTCTTAGGCGTGGGAGAGGCCTACAGGCCCA AGGATATGGTGTCCGAATCCAGGATGCTGGAGTTTATCTGCTGTATAGCCAGGTCCTGTTTCAAGACGTGACTTTCACCATGGGTCAGGTGGTGTCTCGA GAAGGCCAAGGAAGGCAGGAGACTCTATTCCGATGTATAAGAAGTATGCCCTCCCACCCGGACCGGGCCTACAACAGCTGCTATAGCGCAGGTGTCTTCC ATTTACACCAAGGGGATATTCTGAGTGTCATAATTCCCCGGGCAAGGGCGAAACTTAACCTCTCTCCACATGGAACCTTCCTGGGACTTTGATTTTACGG ATATCTTGCTTCTGTTCCCCATGGAGCTCCGAATTCTTGCGTGTGTGTAGATGAGGGGCGGGGGACGGGCGCCAGGCATTGTCCAGACCTGGTCGGGGCC CACTGGAAGCATCCAGAACAGCACCACCATCTAGCGGCCGCTCGAGGGAAGCACCCGCCGGTTGGCCGAAGTCCACGAAGCCGCCCTCTGCTAGGGAAAA CCCCTGGTTCTCCATGCCACACCTCTCTCCAGGTGCCCTCTGCCTCTTCACCCCACAAGAAGCCTTATCCTACGTCCTTCTCTCCATCTATCGGACCCCA GTTTCCATCACTATCTCCAGAGATGTAGCTATTATGCGCCCGTCTACAGGGGGTGCCCGACGATGACGGTGCCTTCGCAGTCAAATTACTCTTCGGGTCC CAAGGTTTGGCTTTCACGCGCTCCATTGCCCCGGCGTGGCAGGCCATTCCAAGCCCTTCCGGGCTGGAACTGGTGTCGGAGGAGCCTCGGGTGTATCGTA CGCCCTGGTGTTGGTGTTGCCTCACTCCTCTGAGCTCTTCTTTCTGATCAAGCCCTGCTTAAAGTTAAATAAAATAGAATGAATGATACCCCGGC

primer-113239 (forward primer)
primer-113220 (reverse primer)
Single exon skipping

Frame 0

PEPCVLGRNPAVAGGLEAAALSLRPEPYVRAFL GKQEVLLANFSTGSSAGLIPTHPAQP*PQNSASF LLPCPWFSSPSSPPLLSHLQSPLVNCPSDLCCA *PRGSSTLALTLDTAQLGPPSCSWHNAL*PANL PSPNPGAAPGFLRTACSSWVSLAALSFLEGLEPN SPEAEGGWRVSRQRWPHDGVPGALTVPLACFPP PSFLFSSSFLFLLA*QPSSLLHHCPYPYPPRHL LATPLLKPQLLAGSPAHASLISFLASPQRASRQH GGPSQRAGTLSCPLVELGGSSGGRGLCHGSADP TNRAAEPQERGEPAAGDRRPLPEWGRVSLAESP GAEFRCPGSLGEWGEIPEKESSAHPKTEEAALCP APGSH*RHLQG*LRCDRGDVATSS*AWERPTGP RIWCPNPGCWSLSAV*PGPVSRRDFHHGSGGVS RRPRKAGDSIPMYKKYALPPGPGLQQLL*RRCLP FTPRGYSECHNSPGKGET*PLSTWNLPGTLILR ISCFCSPWSSEFLRVCR*GAGDGRQALSRPGRG PLEASRTAPPSSGRSREAPAGWPKSTKPPSAREN PWFSMPHLSPGALCLFTPQEALSYVLLSIYRTP VSITISRDVAIMRPSTGGARR*RCLRSQITLRV PRFGFHALHCPGVAGHSKPFRAGTGVGGASGVSY ALVLVLPHSSELFFLIKPCLKLNKIE*MIPR

Frame 1

RNPVCWGGIPQWPGGLRPLLCLFVQSLM*ELFS GNRKSCLPISAQGVVQALFQHTRPSLNPRTQPV SCFRAPGSPPHRAHPSFPTFSHP**TAPAISAVL DPEGLPPSP*PWTLPSLAPHPAPGTMPSSQPTF PPPTLGPPQGSCALPVPPGCHWQPCPS*RDWNL ILLRLREGGGSQGNAGPTTECQEH*QYP*LAFLL PPFYFQVPFYFSLRNNLLPFCTTARTLTRPATS LLPHS*NHSCWQGPQLMPASSPFLLAPKGPPGN MGGPVREPALSVALWLSWGAALGAVACAMALLTQ QTELQSLRREVSRLQGTGGPSQNGEGYPWQSLP EQSSDALEAWENGERSRKRRAVLTQKQKKQHSV LHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQ GYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSR EGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVF HLHQGDILSVIIPRARAKLNLSPHGTFLGL*FYG YLASVPHGAPNSCVCVDEGRGTGARHCPDLVGA HWKHPEQHHHLAAARGKHPPVGRSPRSRPLLGK TPGSPCHTSLQVPSASSPHKKPYPTSFSPSIGPQ FPSLSPEM*LLCARLQGVPDDDGAFAVKLLFGS QGLAFTRSIAPAWQAIPSPSGLELVSEEPRVYR TPWCWCCLTPLSSSF*SSPA*S*IK*NE*YPG

Frame 2

GTLCAGEESRSGRGA*GRCFVSSSRALCKSFSR ETGSPACQFQHRE*CRPYSNTPGPALTPELSQF LASVPLVLLPIEPTPPFPPSVTPSELPQRSLLC LTPRVFHPRPDPGHCPAWPPILLLAQCPLASQPS LPQPWGRPRVPAHCLFLLGVTGSPVLPRGTGT* FS*G*GRVEGLKATLAPRRSARSTNSTLSLLSS SLLFIFKFLFISPCVTTFFPSAPLPVPLPAPPPP CYPTLETTAVGRVPSSCQPHLLSC*PPKGLQAT WGAQSESRHSQLPSG*VGGQLWGPWLVPWLC*P NKQSCRASGER*AGCRGQEAPPRMGKGIPGRVSR SRVPMPWKPGRMGRDPGKGEQCSPKNRRSSTLS CTWFPLTPPPRMTPM*QR*CGNQLLGVGEAYRP KDMVSESRMLEFICCIARSCFKT*LSPWVRWCLE KAKEGRRLYSDV*EVCPPTRTGPTTAAIAQVSS IYTKGIF*VS*FPGQGRNLTSLHMEPSWDFDFT DILLLFPMELRILACV*MRGGGRAPGIVQTWSGP TGSIQNSTTI*RPLEGSTRRLAEVHEAALC*GK PLVLHATPLSRCPLPLHPTRSLILRPSLHLSDP SFHHYLQRCSYYAPVYRGCPTMTVPSQSNYSSGP KVWLSRAPLPRRGRPFQALPGWNWCRRSLGCIV RPGVGVASLL*ALLSDQALLKVK*NRMNDTP

Sequence TNFSF13.eAug05

CCGGAACCCTGTGTGCTGGGGAGGAATCCCGCAGTGGCCGGGGGGCTTGAGGCCGCTGCTTTGTCTCTTCGTCCAGAGCCTTATGTAAGAGCTTTTCTCG GGAAACAGGAAGTCCTGCTTGCCAATTTCAGCACAGGGAGTAGTGCAGGCCTTATTCCAACACACCCGGCCCAGCCTTAACCCCAGAACTCAGCCAGTTT CTTGCTTCCGTGCCCCTGGTTCTCCTCCCCATCGAGCCCACCCCTCCTTTCCCACCTTCAGTCACCCCTAGTGAACTGCCCCAGCGATCTCTGCTGTGCT TGACCCCGAGGGTCTTCCACCCTCGCCCTGACCCTGGACACTGCCCAGCTTGGCCCCCCATCCTGCTCCTGGCACAATGCCCTCTAGCCAGCCAACCTTC CCTCCCCCAACCCTGGGGCCGCCCCAGGGTTCCTGCGCACTGCCTGTTCCTCCTGGGTGTCACTGGCAGCCCTGTCCTTCCTAGAGGGACTGGAACCTAA TTCTCCTGAGGCTGAGGGAGGGTGGAGGGTCTCAAGGCAACGCTGGCCCCACGACGGAGTGCCAGGAGCACTAACAGTACCCTTAGCTTGCTTTCCTCCT CCCTCCTTTTTATTTTCAAGTTCCTTTTTATTTCTCCTTGCGTAACAACCTTCTTCCCTTCTGCACCACTGCCCGTACCCTTACCCGCCCCGCCACCTCC TTGCTACCCCACTCTTGAAACCACAGCTGTTGGCAGGGTCCCCAGCTCATGCCAGCCTCATCTCCTTTCTTGCTAGCCCCCAAAGGGCCTCCAGGCAACA TGGGGGGCCCAGTCAGAGAGCCGGCACTCTCAGTTGCCCTCTGGTTGAGTTGGGGGGCAGCTCTGGGGGCCGTGGCTTGTGCCATGGCTCTGCTGACCCA ACAAACAGAGCTGCAGAGCCTCAGGAGAGAGGTGAGCCGGCTGCAGGGGACAGGAGGCCCCTCCCAGAATGGGGAAGGGTATCCCTGGCAGAGTCTCCCG GAGCAGAGTTCCGATGCCCTGGAAGCCTGGGAGAATGGGGAGAGATCCCGGAAAAGGAGAGCAGTGCTCACCCAAAAACAGAAGAAGCAGCACTCTGTCC TGCACCTGGTTCCCATTAACGCCACCTCCAAGGATGACTCCGATGTGACAGAGGTGATGTGGCAACCAGCTCTTAGGCGTGGGAGAGGCCTACAGGCCCA AGGATATGGTGTCCGAATCCAGGATGCTGGAGTTTATCTGCTGTATAGCCAGGTCCTGTTTCAAGACGTGACTTTCACCATGGGTCAGGTGGTGTCTCGA GAAGGCCAAGGAAGGCAGGAGACTCTATTCCGATGTATAAGAAGTATGCCCTCCCACCCGGACCGGGCCTACAACAGCTGCTATAGCGCAGGTGTCTTCC ATTTACACCAAGGGGATATTCTGAGTGTCATAATTCCCCGGGCAAGGGCGAAACTTAACCTCTCTCCACATGGAACCTTCCTGGGGTTTGTGAAACTGTG ATTGTGTTATAAAAAGTGGCTCCCAGCTTGGAAGACCAGGGTGGGTACATACTGGAGACAGCCAAGAGCTGAGTATATAAAGGAGAGGGAATGTGCAGGA ACAGAGGCGTCTTCCTGGGTTTGGCTCCCCGTTCCTCACTTTTCCCTTTTCATTCCCACCCCCTAGACTTTGATTTTACGGATATCTTGCTTCTGTTCCC CATGGAGCTCCGAATTCTTGCGTGTGTGTAGATGAGGGGCGGGGGACGGGCGCCAGGCATTGTCCAGACCTGGTCGGGGCCCACTGGAAGCATCCAGAAC AGCACCACCATCTAGCGGCCGCTCGAGGGAAGCACCCGCCGGTTGGCCGAAGTCCACGAAGCCGCCCTCTGCTAGGGAAAACCCCTGGTTCTCCATGCCA CACCTCTCTCCAGGTGCCCTCTGCCTCTTCACCCCACAAGAAGCCTTATCCTACGTCCTTCTCTCCATCTATCGGACCCCAGTTTCCATCACTATCTCCA GAGATGTAGCTATTATGCGCCCGTCTACAGGGGGTGCCCGACGATGACGGTGCCTTCGCAGTCAAATTACTCTTCGGGTCCCAAGGTTTGGCTTTCACGC GCTCCATTGCCCCGGCGTGGCAGGCCATTCCAAGCCCTTCCGGGCTGGAACTGGTGTCGGAGGAGCCTCGGGTGTATCGTACGCCCTGGTGTTGGTGTTG CCTCACTCCTCTGAGCTCTTCTTTCTGATCAAGCCCTGCTTAAAGTTAAATAAAATAGAATGAATGATACCCCGGC

primer-113239 (forward primer)
primer-113220 (reverse primer)
Single exon skipping

Frame 0

PEPCVLGRNPAVAGGLEAAALSLRPEPYVRAFL GKQEVLLANFSTGSSAGLIPTHPAQP*PQNSASF LLPCPWFSSPSSPPLLSHLQSPLVNCPSDLCCA *PRGSSTLALTLDTAQLGPPSCSWHNAL*PANL PSPNPGAAPGFLRTACSSWVSLAALSFLEGLEPN SPEAEGGWRVSRQRWPHDGVPGALTVPLACFPP PSFLFSSSFLFLLA*QPSSLLHHCPYPYPPRHL LATPLLKPQLLAGSPAHASLISFLASPQRASRQH GGPSQRAGTLSCPLVELGGSSGGRGLCHGSADP TNRAAEPQERGEPAAGDRRPLPEWGRVSLAESP GAEFRCPGSLGEWGEIPEKESSAHPKTEEAALCP APGSH*RHLQG*LRCDRGDVATSS*AWERPTGP RIWCPNPGCWSLSAV*PGPVSRRDFHHGSGGVS RRPRKAGDSIPMYKKYALPPGPGLQQLL*RRCLP FTPRGYSECHNSPGKGET*PLSTWNLPGVCETV IVL*KVAPSLEDQGGYILETAKS*VYKGEGMCR NRGVFLGLAPRSSLFPFHSHPLDFDFTDILLLFP MELRILACV*MRGGGRAPGIVQTWSGPTGSIQN STTI*RPLEGSTRRLAEVHEAALC*GKPLVLHA TPLSRCPLPLHPTRSLILRPSLHLSDPSFHHYLQ RCSYYAPVYRGCPTMTVPSQSNYSSGPKVWLSR APLPRRGRPFQALPGWNWCRRSLGCIVRPGVGV ASLL*ALLSDQALLKVK*NRMNDTP

Frame 1

RNPVCWGGIPQWPGGLRPLLCLFVQSLM*ELFS GNRKSCLPISAQGVVQALFQHTRPSLNPRTQPV SCFRAPGSPPHRAHPSFPTFSHP**TAPAISAVL DPEGLPPSP*PWTLPSLAPHPAPGTMPSSQPTF PPPTLGPPQGSCALPVPPGCHWQPCPS*RDWNL ILLRLREGGGSQGNAGPTTECQEH*QYP*LAFLL PPFYFQVPFYFSLRNNLLPFCTTARTLTRPATS LLPHS*NHSCWQGPQLMPASSPFLLAPKGPPGN MGGPVREPALSVALWLSWGAALGAVACAMALLTQ QTELQSLRREVSRLQGTGGPSQNGEGYPWQSLP EQSSDALEAWENGERSRKRRAVLTQKQKKQHSV LHLVPINATSKDDSDVTEVMWQPALRRGRGLQAQ GYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSR EGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVF HLHQGDILSVIIPRARAKLNLSPHGTFLGFVKL* LCYKKWLPAWKTRVGTYWRQPRAEYIKERECAG TEASSWVWLPVPHFSLFIPTP*TLILRISCFCS PWSSEFLRVCR*GAGDGRQALSRPGRGPLEASRT APPSSGRSREAPAGWPKSTKPPSARENPWFSMP HLSPGALCLFTPQEALSYVLLSIYRTPVSITIS RDVAIMRPSTGGARR*RCLRSQITLRVPRFGFHA LHCPGVAGHSKPFRAGTGVGGASGVSYALVLVL PHSSELFFLIKPCLKLNKIE*MIPR

Frame 2

GTLCAGEESRSGRGA*GRCFVSSSRALCKSFSR ETGSPACQFQHRE*CRPYSNTPGPALTPELSQF LASVPLVLLPIEPTPPFPPSVTPSELPQRSLLC LTPRVFHPRPDPGHCPAWPPILLLAQCPLASQPS LPQPWGRPRVPAHCLFLLGVTGSPVLPRGTGT* FS*G*GRVEGLKATLAPRRSARSTNSTLSLLSS SLLFIFKFLFISPCVTTFFPSAPLPVPLPAPPPP CYPTLETTAVGRVPSSCQPHLLSC*PPKGLQAT WGAQSESRHSQLPSG*VGGQLWGPWLVPWLC*P NKQSCRASGER*AGCRGQEAPPRMGKGIPGRVSR SRVPMPWKPGRMGRDPGKGEQCSPKNRRSSTLS CTWFPLTPPPRMTPM*QR*CGNQLLGVGEAYRP KDMVSESRMLEFICCIARSCFKT*LSPWVRWCLE KAKEGRRLYSDV*EVCPPTRTGPTTAAIAQVSS IYTKGIF*VS*FPGQGRNLTSLHMEPSWGL*NC DCVIKSGSQLGRPGWVHTGDSQELSI*RRGNVQE QRRLPGFGSPFLTFPFSFPPPRL*FYGYLASVP HGAPNSCVCVDEGRGTGARHCPDLVGAHWKHPE QHHHLAAARGKHPPVGRSPRSRPLLGKTPGSPCH TSLQVPSASSPHKKPYPTSFSPSIGPQFPSLSP EM*LLCARLQGVPDDDGAFAVKLLFGSQGLAFT RSIAPAWQAIPSPSGLELVSEEPRVYRTPWCWCC LTPLSSSF*SSPA*S*IK*NE*YPG

Sequence TNFSF13.dAug05

CTCGGACATTCAGCAGGTGCTGGCACAGGCCCTGGCTGGGAGGTGGGGCGGGCAGGAGCCAGCCTGGAGGAGGGGCTGAGAGTCAGCAGGCACACGGGAA CCCGGAACCCTGTGTGCTGGGGAGGAATCCCGCAGTGGCCGGGGGGCTTGAGGCCGCTGCTTTGTCTCTTCGTCCAGAGCCTTATGTAAGAGCTTTTCTC GGGAAACAGGAAGTCCTGCTTGCCAATTTCAGCACAGGGAGTAGTGCAGGCCTTATTCCAACACACCCGGCCCAGCCTTAACCCCAGAACTCAGCCAGTT TCTTGCTTCCGTGCCCCTGGTTCTCCTCCCCATCGAGCCCACCCCTCCTTTCCCACCTTCAGTCACCCCTAGTGAACTGCCCCAGCGATCTCTGCTGTGC TTGACCCCGAGGGTCTTCCACCCTCGCCCTGACCCTGGACACTGCCCAGCTTGGCCCCCCATCCTGCTCCTGGCACAATGCCCTCTAGCCAGCCAACCTT CCCTCCCCCAACCCTGGGGCCGCCCCAGGGTTCCTGCGCACTGCCTGTTCCTCCTGGGTGTCACTGGCAGCCCTGTCCTTCCTAGAGGGACTGGAACCTA ATTCTCCTTTTTATTTTCAAGTTCCTTTTTATTTCTCCTTGCGTAACAACCTTCTTCCCTTCTGCACCACTGCCCGTACCCTTACCCGCCCCGCCACCTC CTTGCTACCCCACTCTTGAAACCACAGCTGTTGGCAGGGTCCCCAGCTCATGCCAGCCTCATCTCCTTTCTTGCTAGCCCCCAAAGGGCCTCCAGGCAAC ATGGGGGGCCCAGTCAGAGAGCCGGCACTCTCAGTTGCCCTCTGGTTGAGTTGGGGGGCAGCTCTGGGGGCCGTGGCTTGTGCCATGGCTCTGCTGACCC AACAAACAGAGCTGCAGAGCCTCAGGAGAGAGGTGAGCCGGCTGCAGGGGACAGGAGGCCCCTCCCAGAATGGGGAAGGGTATCCCTGGCAGAGTCTCCC GGAGCAGAGTTCCGATGCCCTGGAAGCCTGGGAGAATGGGGAGAGATCCCGGAAAAGGAGAGCAGTGCTCACCCAAAAACAGAAGAAGCAGCACTCTGTC CTGCACCTGGTTCCCATTAACGCCACCTCCAAGGATGACTCCGATGTGACAGAGGTGATGTGGCAACCAGCTCTTAGGCGTGGGAGAGGCCTACAGGCCC AAGGATATGGTGTCCGAATCCAGGATGCTGGAGTTTATCTGCTGTATAGCCAGGTCCTGTTTCAAGACGTGACTTTCACCATGGGTCAGGTGGTGTCTCG AGAAGGCCAAGGAAGGCAGGAGACTCTATTCCGATGTATAAGAAGTATGCCCTCCCACCCGGACCGGGCCTACAACAGCTGCTATAGCGCAGGTGTCTTC CATTTACACCAAGGGGATATTCTGAGTGTCATAATTCCCCGGGCAAGGGCGAAACTTAACCTCTCTCCACATGGAACCTTCCTGGGGTTTGTGAAACTGT GATTGTGTTATAAAAAGTGGCTCCCAGCTTGGAAGACCAGGACTTTGATTTTACGGATATCTTGCTTCTGTTCCCCATGGAGCTCCGAATTCTTGCGTGT GTGTAGATGAGGGGCGGGGGACGGGCGCCAGGCATTGTCCAGACCTGGTCGGGGCCCACTGGAAGCATCCAGAACAGCACCACCATCTAGCGGCCGCTCG AGGGAAGCACCCGCCGGTTGGCCGAAGTCCACGAAGCCGCCCTCTGCTAGGGAAAACCCCTGGTTCTCCATGCCACACCTCTCTCCAGGTGCCCTCTGCC TCTTCACCCCACAAGAAGCCTTATCCTACGTCCTTCTCTCCATCTATCGGACCCCAGTTTCCATCACTATCTCCAGAGATGTAGCTATTATGCGCCCGTC TACAGGGGGTGCCCGACGATGACGGTGCCTTCGCAGTCAAATTACTCTTCGGGTCCCAAGGTTTGGCTTTCACGCGCTCCATTGCCCCGGCGTGGCAGGC CATTCCAAGCCCTTCCGGGCTGGAACTGGTGTCGGAGGAGCCTCGGGTGTATCGTACGCCCTGGTGTTGGTGTTGCCTCACTCCTCTGAGCTCTTCTTTC TGATCAAGCCCTGCTTAAAGTTAAATAAAATAGAATGAATGATACCCCGGC

primer-113239 (forward primer)
primer-113220 (reverse primer)
Single exon skipping

Frame 0

LGHSAGAGTGPGWEVGRAGASLEEGLRVSRHTG TRNPVCWGGIPQWPGGLRPLLCLFVQSLM*ELFS GNRKSCLPISAQGVVQALFQHTRPSLNPRTQPV SCFRAPGSPPHRAHPSFPTFSHP**TAPAISAV LDPEGLPPSP*PWTLPSLAPHPAPGTMPSSQPTF PPPTLGPPQGSCALPVPPGCHWQPCPS*RDWNL ILLFIFKFLFISPCVTTFFPSAPLPVPLPAPPP PCYPTLETTAVGRVPSSCQPHLLSC*PPKGLQAT WGAQSESRHSQLPSG*VGGQLWGPWLVPWLC*P NKQSCRASGER*AGCRGQEAPPRMGKGIPGRVS RSRVPMPWKPGRMGRDPGKGEQCSPKNRRSSTLS CTWFPLTPPPRMTPM*QR*CGNQLLGVGEAYRP KDMVSESRMLEFICCIARSCFKT*LSPWVRWCL EKAKEGRRLYSDV*EVCPPTRTGPTTAAIAQVSS IYTKGIF*VS*FPGQGRNLTSLHMEPSWGL*NC DCVIKSGSQLGRPGL*FYGYLASVPHGAPNSCV CVDEGRGTGARHCPDLVGAHWKHPEQHHHLAAAR GKHPPVGRSPRSRPLLGKTPGSPCHTSLQVPSA SSPHKKPYPTSFSPSIGPQFPSLSPEM*LLCAR LQGVPDDDGAFAVKLLFGSQGLAFTRSIAPAWQA IPSPSGLELVSEEPRVYRTPWCWCCLTPLSSSF *SSPA*S*IK*NE*YPG

Frame 1

SDIQQVLAQALAGRWGGQEPAWRRG*ESAGTRE PGTLCAGEESRSGRGA*GRCFVSSSRALCKSFS RETGSPACQFQHRE*CRPYSNTPGPALTPELSQF LASVPLVLLPIEPTPPFPPSVTPSELPQRSLLC LTPRVFHPRPDPGHCPAWPPILLLAQCPLASQP SLPQPWGRPRVPAHCLFLLGVTGSPVLPRGTGT* FSFLFSSSFLFLLA*QPSSLLHHCPYPYPPRHL LATPLLKPQLLAGSPAHASLISFLASPQRASRQ HGGPSQRAGTLSCPLVELGGSSGGRGLCHGSADP TNRAAEPQERGEPAAGDRRPLPEWGRVSLAESP GAEFRCPGSLGEWGEIPEKESSAHPKTEEAALC PAPGSH*RHLQG*LRCDRGDVATSS*AWERPTGP RIWCPNPGCWSLSAV*PGPVSRRDFHHGSGGVS RRPRKAGDSIPMYKKYALPPGPGLQQLL*RRCL PFTPRGYSECHNSPGKGET*PLSTWNLPGVCETV IVL*KVAPSLEDQDFDFTDILLLFPMELRILAC V*MRGGGRAPGIVQTWSGPTGSIQNSTTI*RPL EGSTRRLAEVHEAALC*GKPLVLHATPLSRCPLP LHPTRSLILRPSLHLSDPSFHHYLQRCSYYAPV YRGCPTMTVPSQSNYSSGPKVWLSRAPLPRRGR PFQALPGWNWCRRSLGCIVRPGVGVASLL*ALLS DQALLKVK*NRMNDTP

Frame 2

RTFSRCWHRPWLGGGAGRSQPGGGAESQQAHGN PEPCVLGRNPAVAGGLEAAALSLRPEPYVRAFL GKQEVLLANFSTGSSAGLIPTHPAQP*PQNSAS FLLPCPWFSSPSSPPLLSHLQSPLVNCPSDLCCA *PRGSSTLALTLDTAQLGPPSCSWHNAL*PANL PSPNPGAAPGFLRTACSSWVSLAALSFLEGLEP NSPFYFQVPFYFSLRNNLLPFCTTARTLTRPATS LLPHS*NHSCWQGPQLMPASSPFLLAPKGPPGN MGGPVREPALSVALWLSWGAALGAVACAMALLT QQTELQSLRREVSRLQGTGGPSQNGEGYPWQSLP EQSSDALEAWENGERSRKRRAVLTQKQKKQHSV LHLVPINATSKDDSDVTEVMWQPALRRGRGLQA QGYGVRIQDAGVYLLYSQVLFQDVTFTMGQVVSR EGQGRQETLFRCIRSMPSHPDRAYNSCYSAGVF HLHQGDILSVIIPRARAKLNLSPHGTFLGFVKL *LCYKKWLPAWKTRTLILRISCFCSPWSSEFLRV CR*GAGDGRQALSRPGRGPLEASRTAPPSSGRS REAPAGWPKSTKPPSARENPWFSMPHLSPGALC LFTPQEALSYVLLSIYRTPVSITISRDVAIMRPS TGGARR*RCLRSQITLRVPRFGFHALHCPGVAG HSKPFRAGTGVGGASGVSYALVLVLPHSSELFF LIKPCLKLNKIE*MIPR

Sequence TNFSF13.aAug05

CCTCGCCCTGGTGGTGCACGCCCGGGCTGGGCGCTCAGAGGTCGGGTGGGCGCCCACTCCGTTCGCTGCGCGCACAGCGCCCGGCGAGAGGCTCGGAGTT TGATCACACACAGCGTCCGGCTTCCTGTCCCCAGCGCCCCCTCCCGCCCCGTTTCCCTTGCCCCTCCCTCTCCCCGGCCCGATCCGCCCGCCGGCTCCCC CTCCCCCGATCCCTCGGGTCCCGGGATGGGGGGGCGGTGAGGCAGGCACAGCCCCCCGCCCCCATGGCCGCCCGTCGGAGCCAGAGGCGGAGGGGGCGCC GGGGGGAGCCGGGCACCGCCCTGCTGGTCCCGCTCGCGCTGGGCCTGGGCCTGGCGCTGGCCTGCCTCGGCCTCCTGCTGGCCGTGGTCAGTTTGGGGAG CCGGGCATCGCTGTCCGCCCAGGAGCCTGCCCAGGAGGAGCTGGTGGCAGAGGAGGACCAGGACCCGTCGGAACTGAATCCCCAGACAGAAGAAAGCCAG GATCCTGCGCCTTTCCTGAACCGACTAGTTCGGCCTCGCAGAAGTGCACCTAAAGGCCGGAAAACACGGGCTCGAAGAGCGATCGCAGCCCATTATGAAG TTCATCCACGACCTGGACAGGACGGAGCGCAGGCAGGTGTGGACGGGACAGTGAGTGGCTGGGAGGAAGCCAGAATCAACAGCTCCAGCCCTCTGCGCTA CAACCGCCAGATCGGGGAGTTTATAGTCACCCGGGCTGGGCTCTACTACCTGTACTGTCAGAGTTCCGATGCCCTGGAAGCCTGGGAGAATGGGGAGAGA TCCCGGAAAAGGAGAGCAGTGCTCACCCAAAAACAGAAGAAGCAGCACTCTGTCCTGCACCTGGTTCCCATTAACGCCACCTCCAAGGATGACTCCGATG TGACAGAGGTGATGTGGCAACCAGCTCTTAGGCGTGGGAGAGGCCTACAGGCCCAAGGATATGGTGTCCGAATCCAGGATGCTGGAGTTTATCTGCTGTA TAGCCAGGTCCTGTTTCAAGACGTGACTTTCACCATGGGTCAGGTGGTGTCTCGAGAAGGCCAAGGAAGGCAGGAGACTCTATTCCGATGTATAAGAAGT ATGCCCTCCCACCCGGACCGGGCCTACAACAGCTGCTATAGCGCAGGTGTCTTCCATTTACACCAAGGGGATATTCTGAGTGTCATAATTCCCCGGGCAA GGGCGAAACTTAACCTCTCTCCACATGGAACCTTCCTGGGGTTTGTGAAACTGTGATTGTGTTATAAAAAGTGGCTCCCAGCTTGGAAGACCAGGGTGGG TACATACTGGAGACAGCCAAGAGCTGAGTATATAAAGGAGAGGGAATGTGCAGGAACAGAGGCGTCTTCCTGGGTTTGGCTCCCCGTTCCTCACTTTTCC CTTTTCATTCCCACCCCCTAGACTTTGATTTTACGGATATCTTGCTTCTGTTCCCCATGGAGCTCCGAATTCTTGCGTGTGTGTAGATGAGGGGCGGGGG ACGGGCGCCAGGCATTGTCCAGACCTGGTCGGGGCCCACTGGAAGCATCCAGAACAGCACCACCATCTAGCGGCCGCTCGAGGGAAGCACCCGCCGGTTG GCCGAAGTCCACGAAGCCGCCCTCTGCTAGGGAAAACCCCTGGTTCTCCATGCCACACCTCTCTCCAGGTGCCCTCTGCCTCTTCACCCCACAAGAAGCC TTATCCTACGTCCTTCTCTCCATCTATCGGACCCCAGTTTCCATCACTATCTCCAGAGATGTAGCTATTATGCGCCCGTCTACAGGGGGTGCCCGACGAT GACGGTGCCTTCGCAGTCAAATTACTCTTCGGGTCCCAAGGTTTGGCTTTCACGCGCTCCATTGCCCCGGCGTGGCAGGCCATTCCAAGCCCTTCCGGGC TGGAACTGGTGTCGGAGGAGCCTCGGGTGTATCGTACGCCCTGGTGTTGGTGTTGCCTCACTCCTCTGAGCTCTTCTTTCTGATCAAGCCCTGCTTAAAG TTAAATAAAATAGAATGAATGATACCCCGGC

primer-113239 (forward primer)
primer-113220 (reverse primer)
Single exon skipping

Frame 0

PRPGGARPGWALRGRVGAHSVRCAHSARREARS LITHSVRLPVPSAPSRPVSLAPPSPRPDPPAGSP SPDPSGPGMGGR*GRHSPPPPWPPVGARGGGGA GGSRAPPCWSRSRWAWAWRWPASASCWPWSVWG AGHRCPPRSLPRRSWWQRRTRTRRN*IPRQKKAR ILRLS*TD*FGLAEVHLKAGKHGLEERSQPIMK FIHDLDRTERRQVWTGQ*VAGRKPESTAPALCA TTARSGSL*SPGLGSTTCTVRVPMPWKPGRMGRD PGKGEQCSPKNRRSSTLSCTWFPLTPPPRMTPM *QR*CGNQLLGVGEAYRPKDMVSESRMLEFICC IARSCFKT*LSPWVRWCLEKAKEGRRLYSDV*EV CPPTRTGPTTAAIAQVSSIYTKGIF*VS*FPGQ GRNLTSLHMEPSWGL*NCDCVIKSGSQLGRPGW VHTGDSQELSI*RRGNVQEQRRLPGFGSPFLTFP FSFPPPRL*FYGYLASVPHGAPNSCVCVDEGRG TGARHCPDLVGAHWKHPEQHHHLAAARGKHPPV GRSPRSRPLLGKTPGSPCHTSLQVPSASSPHKKP YPTSFSPSIGPQFPSLSPEM*LLCARLQGVPDD DGAFAVKLLFGSQGLAFTRSIAPAWQAIPSPSG LELVSEEPRVYRTPWCWCCLTPLSSSF*SSPA*S *IK*NE*YPG

Frame 1

LALVVHARAGRSEVGWAPTPFAARTAPGERLGV *SHTASGFLSPAPPPAPFPLPLPLPGPIRPPAP PPPIPRVPGWGGGEAGTAPRPHGRPSEPEAEGAP GGAGHRPAGPARAGPGPGAGLPRPPAGRGQFGE PGIAVRPGACPGGAGGRGGPGPVGTESPDRRKP GSCAFPEPTSSASQKCT*RPENTGSKSDRSPL*S SSTTWTGRSAGRCGRDSEWLGGSQNQQLQPSAL QPPDRGVYSHPGWALLPVLSEFRCPGSLGEWGE IPEKESSAHPKTEEAALCPAPGSH*RHLQG*LRC DRGDVATSS*AWERPTGPRIWCPNPGCWSLSAV *PGPVSRRDFHHGSGGVSRRPRKAGDSIPMYKK YALPPGPGLQQLL*RRCLPFTPRGYSECHNSPGK GET*PLSTWNLPGVCETVIVL*KVAPSLEDQGG YILETAKS*VYKGEGMCRNRGVFLGLAPRSSLF PFHSHPLDFDFTDILLLFPMELRILACV*MRGGG RAPGIVQTWSGPTGSIQNSTTI*RPLEGSTRRL AEVHEAALC*GKPLVLHATPLSRCPLPLHPTRS LILRPSLHLSDPSFHHYLQRCSYYAPVYRGCPTM TVPSQSNYSSGPKVWLSRAPLPRRGRPFQALPG WNWCRRSLGCIVRPGVGVASLL*ALLSDQALLK VK*NRMNDTP

Frame 2

SPWWCTPGLGAQRSGGRPLRSLRAQRPARGSEF DHTQRPASCPQRPLPPRFPCPSLSPARSARRLP LPRSLGSRDGGAVRQAQPPAPMAARRSQRRRGR RGEPGTALLVPLALGLGLALACLGLLLAVVSLGS RASLSAQEPAQEELVAEEDQDPSELNPQTEESQ DPAPFLNRLVRPRRSAPKGRKTRARRAIAAHYE VHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRY NRQIGEFIVTRAGLYYLYCQSSDALEAWENGER SRKRRAVLTQKQKKQHSVLHLVPINATSKDDSD VTEVMWQPALRRGRGLQAQGYGVRIQDAGVYLLY SQVLFQDVTFTMGQVVSREGQGRQETLFRCIRS MPSHPDRAYNSCYSAGVFHLHQGDILSVIIPRA RAKLNLSPHGTFLGFVKL*LCYKKWLPAWKTRVG TYWRQPRAEYIKERECAGTEASSWVWLPVPHFS LFIPTP*TLILRISCFCSPWSSEFLRVCR*GAG DGRQALSRPGRGPLEASRTAPPSSGRSREAPAGW PKSTKPPSARENPWFSMPHLSPGALCLFTPQEA LSYVLLSIYRTPVSITISRDVAIMRPSTGGARR *RCLRSQITLRVPRFGFHALHCPGVAGHSKPFRA GTGVGGASGVSYALVLVLPHSSELFFLIKPCLK LNKIE*MIPR