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Sequences

Sequence BAX.fAug05

TCACGTGACCCGGGCGCGCTGCGGCCGCCCGCGCGGACCCGGCGAGAGGCGGCGGCGGGAGCGGCGGTGATGGACGGGTCCGGGGAGCAGCCCAGAGGCG
GGGGGCCCACCAGCTCTGAGCAGATCATGAAGACAGGGGCCCTTTTGCTTCAGGGGATGATTGCCGCCGTGGACACAGACTCCCCCCGAGAGGTCTTTTT
CCGAGTGGCAGCTGACATGTTTTCTGACGGCAACTTCAACTGGGGCCGGGTTGTCGCCCTTTTCTACTTTGCCAGCAAACTGGTGCTCAAGGCCCTGTGC
ACCAAGGTGCCGGAACTGATCAGAACCATCATGGGCTGGACATTGGACTTCCTCCGGGAGCGGCTGTTGGGCTGGATCCAAGACCAGGGTGGTTGGGACG
GCCTCCTCTCCTACTTTGGGACGCCCACGTGGCAGACCGTGACCATCTTTGTGGCGGGAGTGCTCACCGCCTCACTCACCATCTGGAAGAAGATGGGCTG
AGGCCCCCAGCTGCCTTGGACTGTGTTTTTCCTCCATAAATTATGGCATTTTTCTGGGAGGGGTGGGGATTGGGGGACGTGGGCATTTTTCTTACTTTTG
TAATTATTGGGGGGTGTGGGGAAGAGTGGTCTTGAGGGGGTAATAAACCTCCTTCGGGACACA
  • 113306 (forward primer)
  • BAX-4 (reverse primer)
  • Single exon skipping

Frame 0

SRDPGALRPPARTRREAAAGAAVMDGSGEQPRG
GGPTSSEQIMKTGALLLQGMIAAVDTDSPREVFF
RVAADMFSDGNFNWGRVVALFYFASKLVLKALC
TKVPELIRTIMGWTLDFLRERLLGWIQDQGGWD
GLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG*
GPQLPWTVFFLHKLWHFSGRGGDWGTWAFFLLL
*LLGGVGKSGLEGVINLLRDT

Frame 1

HVTRARCGRPRGPGERRRRERR*WTGPGSSPEA
GGPPALSRS*RQGPFCFRG*LPPWTQTPPERSF
SEWQLTCFLTATSTGAGLSPFSTLPANWCSRPCA
PRCRN*SEPSWAGHWTSSGSGCWAGSKTRVVGT
ASSPTLGRPRGRP*PSLWRECSPPHSPSGRRWA
EAPSCLGLCFSSINYGIFLGGVGIGGRGHFSYFC
NYWGVWGRVVLRG**TSFGT

Frame 2

T*PGRAAAARADPARGGGGSGGDGRVRGAAQRR
GAHQL*ADHEDRGPFASGDDCRRGHRLPPRGLF
PSGS*HVF*RQLQLGPGCRPFLLCQQTGAQGPV
HQGAGTDQNHHGLDIGLPPGAAVGLDPRPGWLGR
PPLLLWDAHVADRDHLCGGSAHRLTHHLEEDGL
RPPAALDCVFPP*IMAFFWEGWGLGDVGIFLTF
VIIGGCGEEWS*GGNKPPSGH

Sequence BAX.bAug05

TCACGTGACCCGGGCGCGCTGCGGCCGCCCGCGCGGACCCGGCGAGAGGCGGCGGCGGGAGCGGCGGTGATGGACGGGTCCGGGGAGCAGCCCAGAGGCG
GGGGGCCCACCAGCTCTGAGCAGATCATGAAGACAGGGGCCCTTTTGCTTCAGGGTTTCATCCAGGATCGAGCAGGGCGAATGGGGGGGGAGGCACCCGA
GCTGGCCCTGGACCCGGTGCCTCAGGATGCGTCCACCAAGAAGCTGAGCGAGTGTCTCAAGCGCATCGGGGACGAACTGGACAGTAACATGGAGCTGCAG
AG
GATGATTGCCGCCGTGGACACAGACTCCCCCCGAGAGGTCTTTTTCCGAGTGGCAGCTGACATGTTTTCTGACGGCAACTTCAACTGGGGCCGGGTTG
TCGCCCTTTTCTACTTTGCCAGCAAACTGGTGCTCAAGGCCCTGTGCACCAAGGTGCCGGAACTGATCAGAACCATCATGGGCTGGACATTGGACTTCCT
CCGGGAGCGGCTGTTGGGCTGGATCCAAGACCAGGGTGGTTGGGACGGCCTCCTCTCCTACTTTGGGACGCCCACGTGGCAGACCGTGACCATCTTTGTG
GCGGGAGTGCTCACCGCCTCACTCACCATCTGGAAGAAGATGGGCTGAGGCCCCCAGCTGCCTTGGACTGTGTTTTTCCTCCATAAATTATGGCATTTTT
CTGGGAGGGGTGGGGATTGGGGGACGTGGGCATTTTTCTTACTTTTGTAATTATTGGGGGGTGTGGGGAAGAGTGGTCTTGAGGGGGTAATAAACCTCCT
TCGGGACACA
  • 113306 (forward primer)
  • BAX-4 (reverse primer)
  • Single exon skipping

Frame 0

SRDPGALRPPARTRREAAAGAAVMDGSGEQPRG
GGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPE
LALDPVPQDASTKKLSECLKRIGDELDSNMELQ
R
MIAAVDTDSPREVFFRVAADMFSDGNFNWGRV
VALFYFASKLVLKALCTKVPELIRTIMGWTLDFL
RERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFV
AGVLTASLTIWKKMG*GPQLPWTVFFLHKLWHF
SGRGGDWGTWAFFLLL*LLGGVGKSGLEGVINLL
RDT

Frame 1

HVTRARCGRPRGPGERRRRERR*WTGPGSSPEA
GGPPALSRS*RQGPFCFRVSSRIEQGEWGGRHP
SWPWTRCLRMRPPRS*ASVSSASGTNWTVTWSCR
G*LPPWTQTPPERSFSEWQLTCFLTATSTGAGL
SPFSTLPANWCSRPCAPRCRN*SEPSWAGHWTS
SGSGCWAGSKTRVVGTASSPTLGRPRGRP*PSLW
RECSPPHSPSGRRWAEAPSCLGLCFSSINYGIF
LGGVGIGGRGHFSYFCNYWGVWGRVVLRG**TS
FGT

Frame 2

T*PGRAAAARADPARGGGGSGGDGRVRGAAQRR
GAHQL*ADHEDRGPFASGFHPGSSRANGGGGTR
AGPGPGASGCVHQEAERVSQAHRGRTGQ*HGAA
E
DDCRRGHRLPPRGLFPSGS*HVF*RQLQLGPGC
RPFLLCQQTGAQGPVHQGAGTDQNHHGLDIGLP
PGAAVGLDPRPGWLGRPPLLLWDAHVADRDHLC
GGSAHRLTHHLEEDGLRPPAALDCVFPP*IMAFF
WEGWGLGDVGIFLTFVIIGGCGEEWS*GGNKPP
SGH

Sequence BAX.eAug05

TCACGTGACCCGGGCGCGCTGCGGCCGCCCGCGCGGACCCGGCGAGAGGCGGCGGCGGGAGCGGCGGTGATGGACGGGTCCGGGGAGCAGCCCAGAGGCG
GGGGGCCCACCAGCTCTGAGCAGATCATGAAGACAGGGGCCCTTTTGCTTCAGGGTTTCATCCAGGATCGAGCAGGGCGAATGGGGGGGGAGGCACCCGA
GCTGGCCCTGGACCCGGTGCCTCAGGATGCGTCCACCAAGAAGCTGAGCGAGTGTCTCAAGCGCATCGGGGACGAACTGGACAGTAACATGGAGCTGCAG
AG
GATGATTGCCGCCGTGGACACAGACTCCCCCCGAGAGGTCTTTTTCCGAGTGGCAGCTGACATGTTTTCTGACGGCAACTTCAACTGGGGCCGGGTTG
TCGCCCTTTTCTACTTTGCCAGCAAACTGGTGCTCAAGGCTGGCGTGAAATGGCGTGATCTGGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATT
CACCTGCCTCAGCATCCCAAGGAGCTGGGATTACAGGCCCTGTGCACCAAGGTGCCGGAACTGATCAGAACCATCATGGGCTGGACATTGGACTTCCTCC
GGGAGCGGCTGTTGGGCTGGATCCAAGACCAGGGTGGTTGGGACGGCCTCCTCTCCTACTTTGGGACGCCCACGTGGCAGACCGTGACCATCTTTGTGGC
GGGAGTGCTCACCGCCTCACTCACCATCTGGAAGAAGATGGGCTGAGGCCCCCAGCTGCCTTGGACTGTGTTTTTCCTCCATAAATTATGGCATTTTTCT
GGGAGGGGTGGGGATTGGGGGACGTGGGCATTTTTCTTACTTTTGTAATTATTGGGGGGTGTGGGGAAGAGTGGTCTTGAGGGGGTAATAAACCTCCTTC
GGGACACA
  • 113306 (forward primer)
  • BAX-4 (reverse primer)
  • Single exon skipping

Frame 0

SRDPGALRPPARTRREAAAGAAVMDGSGEQPRG
GGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPE
LALDPVPQDASTKKLSECLKRIGDELDSNMELQ
R
MIAAVDTDSPREVFFRVAADMFSDGNFNWGRV
VALFYFASKLVLKAGVKWRDLGSLQPLPPGFKRF
TCLSIPRSWDYRPCAPRCRN*SEPSWAGHWTSS
GSGCWAGSKTRVVGTASSPTLGRPRGRP*PSLW
RECSPPHSPSGRRWAEAPSCLGLCFSSINYGIFL
GGVGIGGRGHFSYFCNYWGVWGRVVLRG**TSF
GT

Frame 1

HVTRARCGRPRGPGERRRRERR*WTGPGSSPEA
GGPPALSRS*RQGPFCFRVSSRIEQGEWGGRHP
SWPWTRCLRMRPPRS*ASVSSASGTNWTVTWSCR
G*LPPWTQTPPERSFSEWQLTCFLTATSTGAGL
SPFSTLPANWCSRLA*NGVIWAHCNLCLLGSSD
SPASASQGAGITGPVHQGAGTDQNHHGLDIGLPP
GAAVGLDPRPGWLGRPPLLLWDAHVADRDHLCG
GSAHRLTHHLEEDGLRPPAALDCVFPP*IMAFF
WEGWGLGDVGIFLTFVIIGGCGEEWS*GGNKPPS
GH

Frame 2

T*PGRAAAARADPARGGGGSGGDGRVRGAAQRR
GAHQL*ADHEDRGPFASGFHPGSSRANGGGGTR
AGPGPGASGCVHQEAERVSQAHRGRTGQ*HGAA
E
DDCRRGHRLPPRGLFPSGS*HVF*RQLQLGPGC
RPFLLCQQTGAQGWREMA*SGLTATSASWVQAI
HLPQHPKELGLQALCTKVPELIRTIMGWTLDFL
RERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVA
GVLTASLTIWKKMG*GPQLPWTVFFLHKLWHFS
GRGGDWGTWAFFLLL*LLGGVGKSGLEGVINLL
RDT

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