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Sequences

Sequence BCL2L12.dAug05

CTCCTGCTGTGCATCCTGCCGTAGGCCGTGCTTCCAAGGGATGCGGAAGCGCGTGCGGCTCTTGTTCACCCAGGCCACGCCCTCCAGTTGCCCCAGGTCC
AGCTGCGACACCAGCCAGGGCAGGATCCGTGGCTTTGGGGTTCCCATGGTCCGGCCTGCGCGTATAGGGCATTTCCTGGGCGCGACCGGCCTCCCCCGGA
CCCACCTGGCCTGGAGTTTCCGCACCCAGACCTCCTTCTCACGGGCCACGGCACAGGTCCTTCACCCATATTTTCGGGGGTACAAACAGGAAACCTCCTC
TTCCCATCCTCCCATCCTCCCGAGAGGCTCTCTAATCAGCTAGGGTTCCTTCCCATATCCATGGCACATCCTTCCCCAGCGTCTTCAGTGCAGACCCTCC
ACTCCCTCAATTCCGCCAGTATAGACCTCCTCCCTCCCCCACATCATCGAAAGTAAGTATCCCCACTTTCAGGGTAGCATCCTCTTTCCCTAGTTATTTC
AGTGCAGAATCGATTCACGTGTAAGCCTCTACCTCCTGCACTTACCCCAATGTAGACCCCCTTCCACAGTCCCCCTACAGAAGATCTCCCAAAACATTTC
CAACACAGAACTTCCATTCAATTCCCCTCCGACTGCCCGCCTCCCTCCTCCAGGACAGAGCACGCCCCAGGTTTCGAGACTGAACTACCCCCATCTACGG
AGTCCACCCCTCCCTCTCTAGAACCCCCTCAGTGTAGACGCCTCCTCTTTTCCTCTTTCCTCCCTACTTTTTCTAGTTTTTCTGCAGCCGACCTCCAGCG
TCGGCCACTGTAGCTCCTTCCTTGCTCCACTTTCCCCAGAGTACACAGCCTGCCTTTCCACTCTCCGTGCAGACCCATCCTCTTTCCCGCTCCTCGCTCT
CGGACGCCACCAACGCTCTCCCGGGCTCTTCCGCGTTACCTACGATGGAAGGTCGGGGCGTGCGGGCAGCTGGAACCCACCCCTGTCTTGGAGCTCCGGG
TAGCTCTCAAACTCGAGGCTGCGCACCCCCTTTCCCGTCAGCTGAGCTCTAGAGCGCTGGGGCTTTCTTTTTGATCGACTTCTTGAAATAAAACCAACTT
TATCATTCTTTGGGTAACAGACCCAAAAGCCGATGGGACGGCCCGCTGGGCTGTTCCCGCCCCTATGCCCTTTTTTGGGTTTCCGGCCAGAGGCATGCTG
GGAGCGTCACATGCAAATTGAGCGTGCACCCAGCGTTCCGCCCTTTCTACGCTGGGCCGGTTATCGACCCGGCCCAGTGCGCAGGCGCGGGAAAGTTGAA
CTAATAAAGTTTGTACGAGTTCAGTGGAGGAGACCGCAAGTTGAGTGGAGGAGGCGGCGGTGGGGCCCCGGACCAGGTGCCTCCATGGCAGGCTCTGAAG
AGCTGGGGCTCCGGGAAGACACGCTGAGGGTCCTAGCTGCCTTCCTTAGGCGTGGTGAGGCTGCCGGGTCTCCTGTTCCAACTCCACCTAGGCCCAGCTA
CTCCAGACTTCTATGCTTTGGTGGCCCAGCGGCTGGAACAGCTGGTCCAAGAGCAGCTGAAATCTCCGCCCAGCCCAGAATTACAGGGTCCCCCATCGAC
AGAGAAGGAAGCCATAC
TGCGGAGGCTGGTGGCCCTGCTGGAGGAGGAGGCAGAAGTCATTAACCAGAAGCTGGCCTCGGACCCCGCCCTGCGCAGCAAG
CTGGTCCGCCTGTCCTCCGACTCTTTCGCCCGCCTGGTGGAGCTGTTCTGTAGCCGGGATGACAGCTCTCGCCCAAGCCGAGCATGCCCCGGGCCCCCGC
CTCCTTCCCCGGAGCCCCTGGCCCGCCTGGCCCTAGCCATGGAGCTGAGCCGGCGCGTGGCCGGGCTGGGGGGCACCCTGGCCGGACTCAGCGTGGAGCA
CGTGCACAGCTTCACGCCCTGGATCCAGGCCCACGGGGGCTGGGAGGGCATCCTGGCTGTTTCACCCGTGGACTTGAACTTGCCATTGGACTGAGCTCTT
TCTCAGAAGCTGCTACAAGATGACACCTCATGTCCCTGCCCTCTTCGTGTGCTTTTCCAAGTCTTCCTATTCCACTCAGGGCTGTGGGGTGGTGGTTGCC
CTACCTGTTTTTGCCAAAAATAAATTGTTTAAAACTTTTCTTATTAAAAACGTTACAAAGTATTCAA
  • BCL2L12-3 (forward primer)
  • BCL2L12-4 (reverse primer)
  • Single exon skipping

Frame 0

LLLCILP*AVLPRDAEARAALVHPGHALQLPQV
QLRHQPGQDPWLWGSHGPACAYRAFPGRDRPPPD
PPGLEFPHPDLLLTGHGTGPSPIFSGVQTGNLL
FPSSHPPERLSNQLGFLPISMAHPSPASSVQTL
HSLNSASIDLLPPPHHRK*VSPLSG*HPLSLVIS
VQNRFTCKPLPPALTPM*TPFHSPPTEDLPKHF
QHRTSIQFPSDCPPPSSRTEHAPGFETELPPST
ESTPPSLEPPQCRRLLFSSFLPTFSSFSAADLQR
RPL*LLPCSTFPRVHSLPFHSPCRPILFPAPRS
RTPPTLSRALPRYLRWKVGACGQLEPTPVLELR
VALKLEAAHPLSRQLSSRALGLSF*STS*NKTNF
IILWVTDPKADGTARWAVPAPMPFFGFPARGML
GASHAN*ACTQRSALSTLGRLSTRPSAQARES*
TNKVCTSSVEETAS*VEEAAVGPRTRCLHGRL*R
AGAPGRHAEGPSCLP*AW*GCRVSCSNST*AQL
LQTSMLWWPSGWNSWSKSS*NLRPAQNYRVPHR
QRRKPY
CGGWWPCWRRRQKSLTRSWPRTPPCAAS
WSACPPTLSPAWWSCSVAGMTALAQAEHAPGPR
LLPRSPWPAWP*PWS*AGAWPGWGAPWPDSAWS
TCTASRPGSRPTGAGRASWLFHPWT*TCHWTELF
LRSCYKMTPHVPALFVCFSKSSYSTQGCGVVVA
LPVFAKNKLFKTFLIKNVTKYS

Frame 1

SCCASCRRPCFQGMRKRVRLLFTQATPSSCPRS
SCDTSQGRIRGFGVPMVRPARIGHFLGATGLPR
THLAWSFRTQTSFSRATAQVLHPYFRGYKQETSS
SHPPILPRGSLIS*GSFPYPWHILPQRLQCRPS
TPSIPPV*TSSLPHIIESKYPHFQGSILFP*LF
QCRIDSRVSLYLLHLPQCRPPSTVPLQKISQNIS
NTELPFNSPPTARLPPPGQSTPQVSRLNYPHLR
SPPLPL*NPLSVDASSFPLSSLLFLVFLQPTSS
VGHCSSFLAPLSPEYTACLSTLRADPSSFPLLAL
GRHQRSPGLFRVTYDGRSGRAGSWNPPLSWSSG
*LSNSRLRTPFPVS*ALERWGFLFDRLLEIKPT
LSFFG*QTQKPMGRPAGLFPPLCPFLGFRPEACW
ERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVE
LIKFVRVQWRRPQVEWRRRRWGPGPGASMAGSE
ELGLREDTLRVLAAFLRRGEAAGSPVPTPPRPSY
SRLLCFGGPAAGTAGPRAAEISAQPRITGSPID
REGSHT
AEAGGPAGGGGRSH*PEAGLGPRPAQQ
AGPPVLRLFRPPGGAVL*PG*QLSPKPSMPRAPA
SFPGAPGPPGPSHGAEPARGRAGGHPGRTQRGA
RAQLHALDPGPRGLGGHPGCFTRGLELAIGLSS
FSEAATR*HLMSLPSSCAFPSLPIPLRAVGWWLP
YLFLPKINCLKLFLLKTLQSIQ

Frame 2

PAVHPAVGRASKGCGSACGSCSPRPRPPVAPGP
AATPARAGSVALGFPWSGLRV*GISWARPASPG
PTWPGVSAPRPPSHGPRHRSFTHIFGGTNRKPP
LPILPSSREAL*SARVPSHIHGTSFPSVFSADPP
LPQFRQYRPPPSPTSSKVSIPTFRVASSFPSYF
SAESIHV*ASTSCTYPNVDPLPQSPYRRSPKTF
PTQNFHSIPLRLPASLLQDRARPRFRD*TTPIYG
VHPSLSRTPSV*TPPLFLFPPYFF*FFCSRPPA
SATVAPSLLHFPQSTQPAFPLSVQTHPLSRSSL
SDATNALPGSSALPTMEGRGVRAAGTHPCLGAPG
SSQTRGCAPPFPSAEL*SAGAFFLIDFLK*NQL
YHSLGNRPKSRWDGPLGCSRPYALFWVSGQRHA
GSVTCKLSVHPAFRPFYAGPVIDPAQCAGAGKLN
**SLYEFSGGDRKLSGGGGGGAPDQVPPWQALK
SWGSGKTR*GS*LPSLGVVRLPGLLFQLHLGPA
TPDFYALVAQRLEQLVQEQLKSPPSPELQGPPST
EKEAI
LRRLVALLEEEAEVINQKLASDPALRSK
LVRLSSDSFARLVELFCSRDDSSRPSRACPGPP
PPSPEPLARLALAMELSRRVAGLGGTLAGLSVEH
VHSFTPWIQAHGGWEGILAVSPVDLNLPLD*AL
SQKLLQDDTSCPCPLRVLFQVFLFHSGLWGGGC
PTCFCQK*IV*NFSY*KRYKVF

Sequence BCL2L12.cAug05

CTCCTGCTGTGCATCCTGCCGTAGGCCGTGCTTCCAAGGGATGCGGAAGCGCGTGCGGCTCTTGTTCACCCAGGCCACGCCCTCCAGTTGCCCCAGGTCC
AGCTGCGACACCAGCCAGGGCAGGATCCGTGGCTTTGGGGTTCCCATGGTCCGGCCTGCGCGTATAGGGCATTTCCTGGGCGCGACCGGCCTCCCCCGGA
CCCACCTGGCCTGGAGTTTCCGCACCCAGACCTCCTTCTCACGGGCCACGGCACAGGTCCTTCACCCATATTTTCGGGGGTACAAACAGGAAACCTCCTC
TTCCCATCCTCCCATCCTCCCGAGAGGCTCTCTAATCAGCTAGGGTTCCTTCCCATATCCATGGCACATCCTTCCCCAGCGTCTTCAGTGCAGACCCTCC
ACTCCCTCAATTCCGCCAGTATAGACCTCCTCCCTCCCCCACATCATCGAAAGTAAGTATCCCCACTTTCAGGGTAGCATCCTCTTTCCCTAGTTATTTC
AGTGCAGAATCGATTCACGTGTAAGCCTCTACCTCCTGCACTTACCCCAATGTAGACCCCCTTCCACAGTCCCCCTACAGAAGATCTCCCAAAACATTTC
CAACACAGAACTTCCATTCAATTCCCCTCCGACTGCCCGCCTCCCTCCTCCAGGACAGAGCACGCCCCAGGTTTCGAGACTGAACTACCCCCATCTACGG
AGTCCACCCCTCCCTCTCTAGAACCCCCTCAGTGTAGACGCCTCCTCTTTTCCTCTTTCCTCCCTACTTTTTCTAGTTTTTCTGCAGCCGACCTCCAGCG
TCGGCCACTGTAGCTCCTTCCTTGCTCCACTTTCCCCAGAGTACACAGCCTGCCTTTCCACTCTCCGTGCAGACCCATCCTCTTTCCCGCTCCTCGCTCT
CGGACGCCACCAACGCTCTCCCGGGCTCTTCCGCGTTACCTACGATGGAAGGTCGGGGCGTGCGGGCAGCTGGAACCCACCCCTGTCTTGGAGCTCCGGG
TAGCTCTCAAACTCGAGGCTGCGCACCCCCTTTCCCGTCAGCTGAGCTCTAGAGCGCTGGGGCTTTCTTTTTGATCGACTTCTTGAAATAAAACCAACTT
TATCATTCTTTGGGTAACAGACCCAAAAGCCGATGGGACGGCCCGCTGGGCTGTTCCCGCCCCTATGCCCTTTTTTGGGTTTCCGGCCAGAGGCATGCTG
GGAGCGTCACATGCAAATTGAGCGTGCACCCAGCGTTCCGCCCTTTCTACGCTGGGCCGGTTATCGACCCGGCCCAGTGCGCAGGCGCGGGAAAGTTGAA
CTAATAAAGTTTGTACGAGTTCAGTGGAGGAGACCGCAAGTTGAGTGGAGGAGGCGGCGGTGGGGCCCCGGACCAGGTGCCTCCATGGCAGGCTCTGAAG
AGCTGGGGCTCCGGGAAGACACGCTGAGGGTCCTAGCTGCCTTCCTTAGGCGTGGTGAGGCTGCCGGGTCTCCTGTTCCAACTCCACCTAGAAGCCCTGC
CCAAGAAGAGCCAACAGACTTCCTGAGCCGCCTTCGAAGATGTCTTCCCTGCTCCCTGGGGCGAGGAGCAGCCCCCTCTGAGTCCCCTCGGCCTTGCTCT
CTGCCCATCCGCCCCTGCTATGGTTTAGAGCCTG
GCCCAGCTACTCCAGACTTCTATGCTTTGGTGGCCCAGCGGCTGGAACAGCTGGTCCAAGAGCAGC
TGAAATCTCCGCCCAGCCCAGAATTACAGGGTCCCCCATCGACAGAGAAGGAAGCCATACTGCGGAGGCTGGTGGCCCTGCTGGAGGAGGAGGCAGAAGT
CATTAACCAGAAGGAGGGCATCCTGGCTGTTTCACCCGTGGACTTGAACTTGCCATTGGACTGAGCTCTTTCTCAGAAGCTGCTACAAGATGACACCTCA
TGTCCCTGCCCTCTTCGTGTGCTTTTCCAAGTCTTCCTATTCCACTCAGGGCTGTGGGGTGGTGGTTGCCCTACCTGTTTTTGCCAAAAATAAATTGTTT
AAAACTTTTCTTATTAAAAACGTTACAAAGTATTCAA
  • BCL2L12-3 (forward primer)
  • BCL2L12-4 (reverse primer)
  • Single exon skipping

Frame 0

LLLCILP*AVLPRDAEARAALVHPGHALQLPQV
QLRHQPGQDPWLWGSHGPACAYRAFPGRDRPPPD
PPGLEFPHPDLLLTGHGTGPSPIFSGVQTGNLL
FPSSHPPERLSNQLGFLPISMAHPSPASSVQTL
HSLNSASIDLLPPPHHRK*VSPLSG*HPLSLVIS
VQNRFTCKPLPPALTPM*TPFHSPPTEDLPKHF
QHRTSIQFPSDCPPPSSRTEHAPGFETELPPST
ESTPPSLEPPQCRRLLFSSFLPTFSSFSAADLQR
RPL*LLPCSTFPRVHSLPFHSPCRPILFPAPRS
RTPPTLSRALPRYLRWKVGACGQLEPTPVLELR
VALKLEAAHPLSRQLSSRALGLSF*STS*NKTNF
IILWVTDPKADGTARWAVPAPMPFFGFPARGML
GASHAN*ACTQRSALSTLGRLSTRPSAQARES*
TNKVCTSSVEETAS*VEEAAVGPRTRCLHGRL*R
AGAPGRHAEGPSCLP*AW*GCRVSCSNST*KPC
PRRANRLPEPPSKMSSLLPGARSSPL*VPSALL
SAHPPLLWFRAW
PSYSRLLCFGGPAAGTAGPRAA
EISAQPRITGSPIDREGSHTAEAGGPAGGGGRS
H*PEGGHPGCFTRGLELAIGLSSFSEAATR*HL
MSLPSSCAFPSLPIPLRAVGWWLPYLFLPKINCL
KLFLLKTLQSIQ

Frame 1

SCCASCRRPCFQGMRKRVRLLFTQATPSSCPRS
SCDTSQGRIRGFGVPMVRPARIGHFLGATGLPR
THLAWSFRTQTSFSRATAQVLHPYFRGYKQETSS
SHPPILPRGSLIS*GSFPYPWHILPQRLQCRPS
TPSIPPV*TSSLPHIIESKYPHFQGSILFP*LF
QCRIDSRVSLYLLHLPQCRPPSTVPLQKISQNIS
NTELPFNSPPTARLPPPGQSTPQVSRLNYPHLR
SPPLPL*NPLSVDASSFPLSSLLFLVFLQPTSS
VGHCSSFLAPLSPEYTACLSTLRADPSSFPLLAL
GRHQRSPGLFRVTYDGRSGRAGSWNPPLSWSSG
*LSNSRLRTPFPVS*ALERWGFLFDRLLEIKPT
LSFFG*QTQKPMGRPAGLFPPLCPFLGFRPEACW
ERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVE
LIKFVRVQWRRPQVEWRRRRWGPGPGASMAGSE
ELGLREDTLRVLAAFLRRGEAAGSPVPTPPRSPA
QEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCS
LPIRPCYGLEP
GPATPDFYALVAQRLEQLVQEQ
LKSPPSPELQGPPSTEKEAILRRLVALLEEEAEV
INQKEGILAVSPVDLNLPLD*ALSQKLLQDDTS
CPCPLRVLFQVFLFHSGLWGGGCPTCFCQK*IV
*NFSY*KRYKVF

Frame 2

PAVHPAVGRASKGCGSACGSCSPRPRPPVAPGP
AATPARAGSVALGFPWSGLRV*GISWARPASPG
PTWPGVSAPRPPSHGPRHRSFTHIFGGTNRKPP
LPILPSSREAL*SARVPSHIHGTSFPSVFSADPP
LPQFRQYRPPPSPTSSKVSIPTFRVASSFPSYF
SAESIHV*ASTSCTYPNVDPLPQSPYRRSPKTF
PTQNFHSIPLRLPASLLQDRARPRFRD*TTPIYG
VHPSLSRTPSV*TPPLFLFPPYFF*FFCSRPPA
SATVAPSLLHFPQSTQPAFPLSVQTHPLSRSSL
SDATNALPGSSALPTMEGRGVRAAGTHPCLGAPG
SSQTRGCAPPFPSAEL*SAGAFFLIDFLK*NQL
YHSLGNRPKSRWDGPLGCSRPYALFWVSGQRHA
GSVTCKLSVHPAFRPFYAGPVIDPAQCAGAGKLN
**SLYEFSGGDRKLSGGGGGGAPDQVPPWQALK
SWGSGKTR*GS*LPSLGVVRLPGLLFQLHLEAL
PKKSQQTS*AAFEDVFPAPWGEEQPPLSPLGLAL
CPSAPAMV*SL
AQLLQTSMLWWPSGWNSWSKSS
*NLRPAQNYRVPHRQRRKPYCGGWWPCWRRRQK
SLTRRRASWLFHPWT*TCHWTELFLRSCYKMTPH
VPALFVCFSKSSYSTQGCGVVVALPVFAKNKLF
KTFLIKNVTKYS

Sequence BCL2L12.aAug05

CTCCTGCTGTGCATCCTGCCGTAGGCCGTGCTTCCAAGGGATGCGGAAGCGCGTGCGGCTCTTGTTCACCCAGGCCACGCCCTCCAGTTGCCCCAGGTCC
AGCTGCGACACCAGCCAGGGCAGGATCCGTGGCTTTGGGGTTCCCATGGTCCGGCCTGCGCGTATAGGGCATTTCCTGGGCGCGACCGGCCTCCCCCGGA
CCCACCTGGCCTGGAGTTTCCGCACCCAGACCTCCTTCTCACGGGCCACGGCACAGGTCCTTCACCCATATTTTCGGGGGTACAAACAGGAAACCTCCTC
TTCCCATCCTCCCATCCTCCCGAGAGGCTCTCTAATCAGCTAGGGTTCCTTCCCATATCCATGGCACATCCTTCCCCAGCGTCTTCAGTGCAGACCCTCC
ACTCCCTCAATTCCGCCAGTATAGACCTCCTCCCTCCCCCACATCATCGAAAGTAAGTATCCCCACTTTCAGGGTAGCATCCTCTTTCCCTAGTTATTTC
AGTGCAGAATCGATTCACGTGTAAGCCTCTACCTCCTGCACTTACCCCAATGTAGACCCCCTTCCACAGTCCCCCTACAGAAGATCTCCCAAAACATTTC
CAACACAGAACTTCCATTCAATTCCCCTCCGACTGCCCGCCTCCCTCCTCCAGGACAGAGCACGCCCCAGGTTTCGAGACTGAACTACCCCCATCTACGG
AGTCCACCCCTCCCTCTCTAGAACCCCCTCAGTGTAGACGCCTCCTCTTTTCCTCTTTCCTCCCTACTTTTTCTAGTTTTTCTGCAGCCGACCTCCAGCG
TCGGCCACTGTAGCTCCTTCCTTGCTCCACTTTCCCCAGAGTACACAGCCTGCCTTTCCACTCTCCGTGCAGACCCATCCTCTTTCCCGCTCCTCGCTCT
CGGACGCCACCAACGCTCTCCCGGGCTCTTCCGCGTTACCTACGATGGAAGGTCGGGGCGTGCGGGCAGCTGGAACCCACCCCTGTCTTGGAGCTCCGGG
TAGCTCTCAAACTCGAGGCTGCGCACCCCCTTTCCCGTCAGCTGAGCTCTAGAGCGCTGGGGCTTTCTTTTTGATCGACTTCTTGAAATAAAACCAACTT
TATCATTCTTTGGGTAACAGACCCAAAAGCCGATGGGACGGCCCGCTGGGCTGTTCCCGCCCCTATGCCCTTTTTTGGGTTTCCGGCCAGAGGCATGCTG
GGAGCGTCACATGCAAATTGAGCGTGCACCCAGCGTTCCGCCCTTTCTACGCTGGGCCGGTTATCGACCCGGCCCAGTGCGCAGGCGCGGGAAAGTTGAA
CTAATAAAGTTTGTACGAGTTCAGTGGAGGAGACCGCAAGTTGAGTGGAGGAGGCGGCGGTGGGGCCCCGGACCAGGTGCCTCCATGGCAGGCTCTGAAG
AGCTGGGGCTCCGGGAAGACACGCTGAGGGTCCTAGCTGCCTTCCTTAGGCGTGGTGAGGCTGCCGGGTCTCCTGTTCCAACTCCACCTAGAAGCCCTGC
CCAAGAAGAGCCAACAGACTTCCTGAGCCGCCTTCGAAGATGTCTTCCCTGCTCCCTGGGGCGAGGAGCAGCCCCCTCTGAGTCCCCTCGGCCTTGCTCT
CTGCCCATCCGCCCCTGCTATGGTTTAGAGCCTG
GCCCAGCTACTCCAGACTTCTATGCTTTGGTGGCCCAGCGGCTGGAACAGCTGGTCCAAGAGCAGC
TGAAATCTCCGCCCAGCCCAGAATTACAGGGTCCCCCATCGACAGAGAAGGAAGCCATACTGCGGAGGCTGGTGGCCCTGCTGGAGGAGGAGGCAGAAGT
CATTAACCAGAAGCTGGCCTCGGACCCCGCCCTGCGCAGCAAGCTGGTCCGCCTGTCCTCCGACTCTTTCGCCCGCCTGGTGGAGCTGTTCTGTAGCCGG
GATGACAGCTCTCGCCCAAGCCGAGCATGCCCCGGGCCCCCGCCTCCTTCCCCGGAGCCCCTGGCCCGCCTGGCCCTAGCCATGGAGCTGAGCCGGCGCG
TGGCCGGGCTGGGGGGCACCCTGGCCGGACTCAGCGTGGAGCACGTGCACAGCTTCACGCCCTGGATCCAGGCCCACGGGGGCTGGGAGGGCATCCTGGC
TGTTTCACCCGTGGACTTGAACTTGCCATTGGACTGAGCTCTTTCTCAGAAGCTGCTACAAGATGACACCTCATGTCCCTGCCCTCTTCGTGTGCTTTTC
CAAGTCTTCCTATTCCACTCAGGGCTGTGGGGTGGTGGTTGCCCTACCTGTTTTTGCCAAAAATAAATTGTTTAAAACTTTTCTTATTAAAAACGTTACA
AAGTATTCAA
  • BCL2L12-3 (forward primer)
  • BCL2L12-4 (reverse primer)
  • Single exon skipping

Frame 0

LLLCILP*AVLPRDAEARAALVHPGHALQLPQV
QLRHQPGQDPWLWGSHGPACAYRAFPGRDRPPPD
PPGLEFPHPDLLLTGHGTGPSPIFSGVQTGNLL
FPSSHPPERLSNQLGFLPISMAHPSPASSVQTL
HSLNSASIDLLPPPHHRK*VSPLSG*HPLSLVIS
VQNRFTCKPLPPALTPM*TPFHSPPTEDLPKHF
QHRTSIQFPSDCPPPSSRTEHAPGFETELPPST
ESTPPSLEPPQCRRLLFSSFLPTFSSFSAADLQR
RPL*LLPCSTFPRVHSLPFHSPCRPILFPAPRS
RTPPTLSRALPRYLRWKVGACGQLEPTPVLELR
VALKLEAAHPLSRQLSSRALGLSF*STS*NKTNF
IILWVTDPKADGTARWAVPAPMPFFGFPARGML
GASHAN*ACTQRSALSTLGRLSTRPSAQARES*
TNKVCTSSVEETAS*VEEAAVGPRTRCLHGRL*R
AGAPGRHAEGPSCLP*AW*GCRVSCSNST*KPC
PRRANRLPEPPSKMSSLLPGARSSPL*VPSALL
SAHPPLLWFRAW
PSYSRLLCFGGPAAGTAGPRAA
EISAQPRITGSPIDREGSHTAEAGGPAGGGGRS
H*PEAGLGPRPAQQAGPPVLRLFRPPGGAVL*P
G*QLSPKPSMPRAPASFPGAPGPPGPSHGAEPAR
GRAGGHPGRTQRGARAQLHALDPGPRGLGGHPG
CFTRGLELAIGLSSFSEAATR*HLMSLPSSCAF
PSLPIPLRAVGWWLPYLFLPKINCLKLFLLKTLQ
SIQ

Frame 1

SCCASCRRPCFQGMRKRVRLLFTQATPSSCPRS
SCDTSQGRIRGFGVPMVRPARIGHFLGATGLPR
THLAWSFRTQTSFSRATAQVLHPYFRGYKQETSS
SHPPILPRGSLIS*GSFPYPWHILPQRLQCRPS
TPSIPPV*TSSLPHIIESKYPHFQGSILFP*LF
QCRIDSRVSLYLLHLPQCRPPSTVPLQKISQNIS
NTELPFNSPPTARLPPPGQSTPQVSRLNYPHLR
SPPLPL*NPLSVDASSFPLSSLLFLVFLQPTSS
VGHCSSFLAPLSPEYTACLSTLRADPSSFPLLAL
GRHQRSPGLFRVTYDGRSGRAGSWNPPLSWSSG
*LSNSRLRTPFPVS*ALERWGFLFDRLLEIKPT
LSFFG*QTQKPMGRPAGLFPPLCPFLGFRPEACW
ERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVE
LIKFVRVQWRRPQVEWRRRRWGPGPGASMAGSE
ELGLREDTLRVLAAFLRRGEAAGSPVPTPPRSPA
QEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCS
LPIRPCYGLEP
GPATPDFYALVAQRLEQLVQEQ
LKSPPSPELQGPPSTEKEAILRRLVALLEEEAEV
INQKLASDPALRSKLVRLSSDSFARLVELFCSR
DDSSRPSRACPGPPPPSPEPLARLALAMELSRR
VAGLGGTLAGLSVEHVHSFTPWIQAHGGWEGILA
VSPVDLNLPLD*ALSQKLLQDDTSCPCPLRVLF
QVFLFHSGLWGGGCPTCFCQK*IV*NFSY*KRY
KVF

Frame 2

PAVHPAVGRASKGCGSACGSCSPRPRPPVAPGP
AATPARAGSVALGFPWSGLRV*GISWARPASPG
PTWPGVSAPRPPSHGPRHRSFTHIFGGTNRKPP
LPILPSSREAL*SARVPSHIHGTSFPSVFSADPP
LPQFRQYRPPPSPTSSKVSIPTFRVASSFPSYF
SAESIHV*ASTSCTYPNVDPLPQSPYRRSPKTF
PTQNFHSIPLRLPASLLQDRARPRFRD*TTPIYG
VHPSLSRTPSV*TPPLFLFPPYFF*FFCSRPPA
SATVAPSLLHFPQSTQPAFPLSVQTHPLSRSSL
SDATNALPGSSALPTMEGRGVRAAGTHPCLGAPG
SSQTRGCAPPFPSAEL*SAGAFFLIDFLK*NQL
YHSLGNRPKSRWDGPLGCSRPYALFWVSGQRHA
GSVTCKLSVHPAFRPFYAGPVIDPAQCAGAGKLN
**SLYEFSGGDRKLSGGGGGGAPDQVPPWQALK
SWGSGKTR*GS*LPSLGVVRLPGLLFQLHLEAL
PKKSQQTS*AAFEDVFPAPWGEEQPPLSPLGLAL
CPSAPAMV*SL
AQLLQTSMLWWPSGWNSWSKSS
*NLRPAQNYRVPHRQRRKPYCGGWWPCWRRRQK
SLTRSWPRTPPCAASWSACPPTLSPAWWSCSVAG
MTALAQAEHAPGPRLLPRSPWPAWP*PWS*AGA
WPGWGAPWPDSAWSTCTASRPGSRPTGAGRASW
LFHPWT*TCHWTELFLRSCYKMTPHVPALFVCFS
KSSYSTQGCGVVVALPVFAKNKLFKTFLIKNVT
KYS

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