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Sequences

Sequence AKAP13.bAug05

TGAGTTGAAGTGGGGGAAATAGAGGAGTAAATCATTTCACGATGTGTGGTTAAGTGCTGCAGCTCAGGTAACCACCAGTACACAGAGGAAGGGCGGTTTC
TGGAGACAGGGCGGAGAGGAGACCGTGGGTGGGCATTTCCCAGAGCAGCCTCTGCCAGCCACCCTACTTTGATCACTTTGCCGCCGAGCAGCAGCGGCGG
TCAACCTCAGCCTCCCTTAGCAACCTGAGTGCCCCGTCCAGGAGCCTTACTATTGGTCTCATGCAGCGAGATGGGCAGTTCTGCCGTGCAATCCCAGCTC
GCAGTTCTTGCTCCGCGTGTACTCACGGGAGGACTCGCAGGCGTTACCGCCTTCCCGCGTGCCCCGCCCACCCTCCCGAGCGTCTTTCGGCGCATGCGCG
GACTGGAGCTGTGTGCAGGGCCAGCGCGGAGCCCGAGCAGCCGCGGTGAAGCGCCTGTGCTCTGCCGAGACTGCCGTGCCCATTGCTCGCCTCGGTCGCC
GCCGCTTTAGCCGCCTCCGGGGGAGCGGCCGCCTATTGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGC
CGCACGTGTCCTGGGTCATGAAACTTAATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGA
TGATGTAGTGTTTTACTTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTGCTCCTGGT
CATGATTGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACTTTCATTTCGTCCAGGATG
AAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTCTTGACCAGTCAGGACCCCCATCTGGGGA
TGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGTGGAATGTATTGGGGACAGATCAGAGTTTGCATGATGCT
GGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGTTGACGTGGTTCCTGTTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTA
TCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGGAGCGAGGCTATCACAAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGA
CTCCTGGAGCAGTTTATCCTATGAAATACCGTATGGAGACTGTTCTGTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCA
CATCATGAACACCCATTTCCTGGAGACGGTTGCACTGGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGG
ACAGTCTTATGCCCTTAATGATGACAGCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCA
GCGACTTTCTTCTTCTGAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCATAGTTGAG
GAGGAGAATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTGTGGACTCTGGAACTGTAT
CTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTGGAAACAGAAATGAAGAAACTGGAACAAA
ATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAGACTTGGTCATGGAGCCAGGCACAGCCCAGTATTCCTCT
GGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTGCAGGGGAAATGGAACATGGGCTCATGAACCCAGATGCCACTGTTTGGA
AGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTGAGAACTCTAATATTGGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGT
GGATAAAATCAGTGTTCCAAACTGTGCCCCTGCTGCCAGTTCCCTGGATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCC
ACTGAAAAAACAGCAGAAACGGAAACTTCACGAAGTCGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAG
ACAAGATTTCAGATGGATTAGAACCTTATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGA
TGTAATGCCACACCAGAACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACGATAAACTT
TGTGCAGACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCGAGTCCGAAAGCACCACAG
CAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCTCTGACCCTGTAAGGGATACCCAGGAACG
TGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAGATAAACCTTTAACAAATATGCTTGAGGTGGTTTCACAT
CCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAGTAATATCAGACAGTACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAAT
CAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGAAAGAAAAGGGAACAGCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCC
AGATGGAAATTCGAATGAGCCTGATACGCGGCCACTAGAAGACAGGGCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGG
AATACCAGTCTCACAGGACTTGGTGGAGAGCATGAGGGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGC
AAAGTGTGGGTAAGGCCACTTTGGCTTTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAA
GGATAAAGCGGTGACCTGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAGATACTCAA
CAATTTCATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTGCCTTTCTTAAGGCAGAAA
CTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGCCACCAGGAGCAAGTCTGGCCACAGAGTC
AAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAGATGGGTCTGATGGGTCCGATGCTCTTAACTGCAGTCAG
CCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTAGTGCCTGTGAGGTGAGTGGAGATGTGACGGTGGATGTTACAGGGGTTA
ATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATATCACACAACACCCAAGACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGC
CGTTCTAGGTTTGCCAGTGGCTCTACAGGACAAAGCTGTGACTGACCCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAG
CTGGAGGGAGCAGACCACAGCTGTACCATGGGTGACGCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGC
TCCCCACAGACATGGAGCTCTCAGCCCATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCC
CTCTCTACCTTGCATGGTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTGTCATCGAA
CAAGTCAAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCACTAAAGGACTAGAGAGTG
CTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCACGGGGAGCCTTGCAGGATGTTTTGCTGG
AAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGCCAGACGTGAAAGCTGAAGATGAAGTGGATTTTAGAGCA
AGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGATGAAGCAAGGCCCAATGACCCAGGCGATAAACCGAGAAAACTGGTGTA
CAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCAAGCAGAGCCCAGAATGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTC
AAAACAAGGTGTACTTAAAAGAGAATCTGGGAGTGATTCTGACCTCTTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAA
GAGCATTTGGCCTGTGATATCACCGGATCCAGTTCATCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCC
AGATTTTAAAGCCAAACAGGTCAAGAGATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGC
TGACCCAGGCGACGTGGAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTTCTCCCTTC
CGGAGGCACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTTCAATGCGAGTTCTTGGGGATGTTGTCAGGAGACCTC
CCATTCATAGGAGAAG
TTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCATCTCTAGAAGTAAGCTCTGCAAATGCCGA
AGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAGAGGATCTGGAGTCAGACCAGAGAGAACATAGGATGTTT
GATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACATCAGCCATTTCCTCTCCATTGACAAAATCCATCTCATTAATGACAATCA
GCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCTTCCACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAACTATAATTTCCT
GCCACATAGCCCCTCCAAGAAAGATTCTGAATGGAAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCTAGCAGCAAGAAG
AGCAAAGAAAAGGAAAAAGAAAAAGATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACGGGCACACTTTCA
GTTCCATTCCTGTTGTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAGTGCTTTTGTCCA
CAAAGGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCACTGCCCACGGTC
ATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATATTTGCCAATAGACGAT
CCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATGTCAAACACCTGGAAATTCCTGTCTCA
TTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAGGGAGTAGGTACAGACATGAATGAAGGACAACTACTG
GGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATAATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAGATGTGGTCAAAC
GGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCATGTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGATGATGGCGGATCT
GCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTCCCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTGGAGCGGAAGAAG
GAGTCTCTGGTGGATAAAAGTGAAAAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAGAACGTTTAAAGA
AGACATATGGCAAGTTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTTTGTAAAGAAGAA
GATGAGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTCCAAAGAATATTG
CAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGACAGCAAAGTGGCAAGTT
ATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGTCAGATGTTTGCCAAGGAAGATTTGAA
ACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAGGTTCAAGCAGTTCTTCTCACTGACATTTTAGTTTTC
CTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACAGTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAGTGGCACATGAGG
AGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAGATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTGGATTCAGATCAT
TCAGGACACAATCAACACCCTGAACAGAGATGAAGATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGAGCCCGAGAATTA
AAAGAACAACTTCACCAGAAGGACCAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCACCCCTCTCCCAG
AGGATTGCTCCCCAACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGCAATAAATGAGGT
GGAGATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGTCCCGTTTCCCTG
CCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGATGGCCAAGATCTTAGGA
GAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAGCAGGTTGTCCAGAGCGTTGTTCATCT
CTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAGAAACTGGTGCTGAGCGAGAGGGCGCTCACTCGCAGC
TTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAGCAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGCAGGCCCAGTACC
TCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAGAGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGAGGAGGTGCAGCA
GGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAGCTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCCCAGAAACAGCTT
GAGAGGGAACAGGAGCAGCTGCGCCGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGTTTCCCATCCACATACCAAGCTGA
TGAGGATCCCATCGTTCTTCCCCAGTCCTGAGGAGCCCCCCTCGCCATCTGCACCTTCCATAGCCAAATCAGGGTCATTGGACTCAGAACTTTCAGTGTC
CCCAAAAAGGAACAGCATCTCTCGGACACACAAAGATAAGGGGCCTTTTCACATACTGAGTTCAACCAGCCAGACAAACAAAGGACCAGAAGGGCAGAGC
CAGGCCCCTGCGTCCACCTCTGCCTCTACCCGCCTGTTTGGGTTAACAAAGCCAAAGGAAAAGAAGGAGAAAAAAAAGAAGAACAAAACCAGCCGCTCTC
AGCCCGGTGATGGTCCCGCGTCAGAAGTATCAGCAGAGGGTGAAGAGATCTTCTGCTGACCCTCTTCCTCTCTGCTGAGGCAGCTGCCTCCTGATCCTGG
CCAGCCCACCTCTCCTGCTGTCCCCGCGTGCACAAGTCTCTTACACTGGACGCCCACTGCTCCTCAGCGTCCAGTCCTCCTGGGCGGCCCCAGGTCCTGG
ACAATAAGCAACAGATGATATTGAGTGTCGGGTGGGGAAGGAGGCCCAGACTCTGCTTCGGCCATGATTTGTGACTGCCCAGGACTCTCAGGTTGGGCTG
GCCCTACTCAGGATTACACTGAAAGTAATGGCCTCGTAAGTACAGGTGATGGTTTTGGACACGTCAGGAATTCCTAAAGGCTGAAAGAGTGTATCCAAGT
AAGGTCTGAACCTCCGAATGCCTTTTATTTGGGGGAACACAAAACCAAACAGCAGATGTTTTGGACTTGATCTGTGTACGTACATGGGGACCTGTCTGCA
TATACACACGGGGAATGCCAGAAGAAGGCCCAGTCTGCACCAGGCGTCTGGTCAACTTAGCACAAGGGCAGTGCCTGGACGGACCCGGAGCCCCCGCATA
TCAGCAGTTCACCCAGTACTCCTCAGAGACTGGTTTCCCTCTAAACCCATCCCGGGCACATACCACCCGTGTTTTGCATGTATTTCTCATTTCATTTTAG
GGATGACAAACATTTGTGAAACCAGTGAGAGAAGGCTTGATGTGTATAAAAGACGTGATGTGCACCACCTCGATCTCGGTGTTTCAGGCACTAAAGCAAC
AAAACAACCCATAGTATCTCATTCTGTCATCAGATCCAGAAGAAATATCCTGGTTTTCCAGCATGTTTACCCACATGTTTTGGCCATGGATAAAGTGAAG
AGGCCTACTCACCATTATCCCTGCAGCGTGACACCTTTTGATTGTCACTGACCACTCAGAAGGGGCCACGGCCTCCTGGCTGTGTTCCTGAGCCCCCGTC
GTGCCTCTCCCAGACAGCAGCTGTCTGGCCCTTGCTGGGTGAGGGCACACCACTGCCAGGGGTCAGCCTCGCACCCAGGCCAGGCAGAAGCTGTGCTCTG
AAGCTAGGACAGCTGGCTGAGAAGTGGGTTCAGGCGAAGGGTGAAGCCATGTGTAGCAGTTCCTGCCAGTGCAGATCTGGAGAGGAGCTGGCCCGGAAGG
CGTGGTTGTGAAAGCGCCCTTCTTATGTTAGGAGGCCTTGGCAAAATTGGATTTCTTCAAAAATACATGTAAAGGTCTGTTGTTGAATTGTACTCTGCCC
CTGGAAGCAGATACAGATGGCTGCCTGCTGCTCGGCTTTGCTTTTGCTTTTCCCACCGTGTTTTCATCTTTGTTCACTTGAGGCTTTCCCCAGCTGGTGT
GTGCAGGACAGTTCATGGTAATGTTGCCCTCTGAGGCCCCGTACACCAGAAGGGAGGCCCTGGAAAATTTTGTGCTTCCAACGTGGCCTTCAATTCTTGC
TTTTTTGCCCCTCGGAAGCATGGGGCTTTTGAGCACACTTAAAAAAAGAAAAATCTGTAACTTGGTGCTTATTGATGAATTGCAAGCTGGCCTTGCAGAT
GGAGATATTTATCTTTCAGTTTATTTGAAAGAGGTCTGGTTTAAAATTTGTAGCCTACATTTGTTTTATTTATTGTATTTGTGTGTTTGTGTTTGTTTTT
TTTTAAGGGTGAGCCAGGTCTAGCCCAACAGTCTAAACTATCCAGTCAATACCGAGTGAAGTGGCAGCCAGCACTGTTCACTCTGTGTCTTTTGAAGTGC
CTTGAAGGCCCAGATGAAATTTTAAAGGGAGGGGGTCCATGTCCTTCCCTCCCCCACCCCGCCTCATTCTTTAATCAAAGGATGTCTTCTCCCTTGTTTG
AGAATGAAGAAACTCGCCACCTCTGACCTACCTTTGCCTTTTTCTGTCATGGAGAATACTCACCCTTCAGAAACAGACCAAAGGCCAAAACCTGCTGATT
TTTCTATTGAAAATATGTCCCCTTGCAAAGACCCTAAACAAAAAGTTAAGTTTCTTTCTTTCACCTATTTGTACAACTCCAAGTTACAGCTGAATCTGTC
GTGACTTTCCTGAGATCTACCCGGGGCTTGGCTGTCTGTTCTGGGCACTGGCTCCGAGTTCCCCTCCTGGGATTTGCAGGAGGGCAGTACTGAACCTGCA
TTCTTCTCCTTGTAAATGTAGGCCGGGTGCCCCTGTTCTCCGGGTTTGGAACAATACGAGGTTGGTGCTGATGGGATTTACTTGCGTACGTGCTCTTCAC
AAAAACACCGTGGATGCTGAAGTTAGAGCACGTCGCCACAGAGCTTGACATCAATGTTAGAGGGTCTCTTACTCCCCGCCCAGCTGTGATGTTTCATCTG
CTTTGGTTGTTTTGGTGGTCTTTTTTAAAAATAGAGATTTCACATCTGCCCAGACCCCACTCAAAACGATTTGGTCAGGTTCTGGTTGGACAAGTTTAAA
ATCAAAGTAGTGCCCGGAATTCCCTCAAACCACCCAACTTCATCCAGGAATACAGTCTGCAGTGCAGCAACAGAACCGCTTACCAAGAACTGTGCTTACA
TACCTTTGTCATCTCTCTTCCCCCCTTGGAAGTTGTCCTCAGGGGGATTTGTTCCTGTCCTGGGGATTTACCTGGGATGGTGGCTGCCTGTGCTTTTGCT
CATGGCCTTGACAGTGCTCTAGTTGCTGGATCTAATGGCCTGTCTTGGTTTCTATCACATGAGAAGGGGTTGTTTTTTTGGGGTGACTCGGACTGAATTC
CCCATACTGTTTCCACGCCGGGACACCATGTTCTCCATCAAGCTAAAGAAATCACGTGCCTGAAACTGTGCTTAAGTTTTGGGGGAAAGATGGAGTTCCT
ATCCAGAGCCCCCAGATTTCCAGAATCGAGTGAGCTTCCTGGAAGGAGACTGCGTCTTCTCTCAATTCCAGTCATCTCAGTCGTTGTCGTTAGGTGACAT
GTGCACTTTAAATGCTCTCATCGGTTGGCTTCATTTTCAAGACAATCAAATGTATTGACTGTGTTTTCTTCTTAGAAAATGGAGAGGGTTAAAAACATGC
AAACTGCCACTTTCAACCTTTGCCAGTATTCCCTCTACCCCCGTGAGAGCTATCTGGGGGGAAGAATCCTTACCAAGGTTTTTTTGGAAAGGTACGAATC
TTAACTTTTTTCCCCTTCTGTGTCTCAGGGTAATACTATTCAGAGTCGCCCCTTTGCTCATTTTCTCCCGTATTTGTTACCTTCCTGAGGCCTCAGTATT
AGTCGTGAGCACAAAGTTTTGAGACCTTTGGCGTTGTTTCTTGATGTGGGAGGGGAGGTGTTAGTGCATGCAAGGGTTGAACTAGATAGACCCTGCCTTA
GTAGAGGGTGGGACTATAACCTTAGAGGCCAGAACTTGATCCAGAAGTTGCTGTCCACAGAAGTGCTTTCTATTTCATCATTTTTGTTTCTAGGGCTCTT
TTTCTGTAGCCAGGTCTTCCCAAGGATTTTAGTATTTGCATTGGAGTTGAGGTTTACTCTAATGATGGTGGCCCAGCTGTGCCCAGAGGACAGCCAGGCA
GGCCCTGGGAGGGAGTTTAGAAAGACAGTCCTGGTGAATGGGCTTCAAGTGGTCACAAAGAGGGTGGCTGTGAGGTGACCCCAGACACTGCAGAACGATG
TGCACCCTCTGCGTTTTGGATGTCCTTGGAATGTGGGAGCCTAGAAATAACCCTGTGGATGGAATTGGGGCAGCGGCTGCTGGAGATCTGTGTGCCTTGC
CTTCCTTCAGCAGGACCGTCTAGGTGCGCAGCCACCTATGGATGCGTCCCAGCCAGCCCCGTCGCTCTCGTCCATCCTCAGAGACAAAGAAGAGGGCAGG
GAGTTTGGGCTTGGTTTTGAACTTTCCTTTCAATGTAGCAAAGCATTCCTAGTTAACCAGAGCCTTGGAATCTACTGCCTGCTGGCCAGGCTTTAAAATG
AAAAGTGTTTTAATGCTGCCATAAAAGGGAGGCGGGGGGGAGGAAGGGAAAATAAAGGCATCTTTCCAAGTACTCATCTAATTTAATTGTCAAAAGATTG
ATAGGCCATGAATTACTTCTCCATCTCACTAAGGGTTAAAGGCGTGCAACCCCCCACTGGCTGTGTCCCCTGCCACCGAAGTGAGTGACCTGCCCTACAA
CCAGGTGGGACCACCTGTGCTGCAGTCCGGAGGGGCTTCTGCAGGAAGCACTCACCCCCCACACCTTCCCCGGCCTGAGCTTCCCCTACCTTTCGTCACC
ACCTGAGGGCATGAGCACAGGCCATGGGGCGTGCCTGGTGAGTCTGCCTGTGGTTCAGGCTTAGCCTGTGGTCTCCTGTGTGCTGCTGCCCGCATGGGAT
GCGCAGGGGAGGCGTGGGGATCCGCAGGAGGGTGGTTGGGATACACCGGATACCTCTGCTCTCATTGCTTGTTTGCAAATGCTCTATGGACATTTGTGTG
CTAAATCCTATTAAATAAAAAAGACGGGTTAAAACCCAGATGCTGTATATTCATTTGTAATTATGTATAAAGTGAAGCAGTTTTAAACTGTAAAGATTTT
TTTCAGTGTGTTTTCTCGAATTTTGCCACAACATACTGGCTTCGTATTTTATTTATCTTTCTTTCTAGTTACCAGCTTCAGACCCTTGTAAAGTCTCCCT
CAGCCCTTTCAAAAAATAATAAATTTCCTGTGAAGTTCTGG
  • AKAP13-F1 (forward primer)
  • AKAP13-R1 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

*VEVGEIEE*IISRCVVKCCSSGNHQYTEEGRF
LETGRRGDRGWAFPRAASASHPTLITLPPSSSGG
QPQPPLAT*VPRPGALLLVSCSEMGSSAVQSQL
AVLAPRVLTGGLAGVTAFPRAPPTLPSVFRRMR
GLELCAGPARSPSSRGEAPVLCRDCRAHCSPRSP
PL*PPPGERPPIVFLRGEGEELSQLGPRGSPGS
RTCPGS*NLIHSKLPYMVIVLLQCCLLKRTKLK
MM*CFTWYFWVPPSVTVQVLGRSVLIHWRPLLLV
MIVVKQ*RCSSVLPKRAFPCLWWLKKTFISSRM
KRMMQLNS*QPVLEISRL*TLPVFLTSQDPHLG
M*IPLIRSWCWHSGT*SCPRSGMYWGQIRVCMML
ARERH*CILLCGWDC*G*RGSCCRSQVAAELSV
STTRKGRRL*AWPWSEAITSCTSF*PRRMLENQ
TPGAVYPMKYRMETVL*GIIESWTSIH*PLSLIH
IMNTHFLETVALDQFLNL*TSNSN**KQTSSRW
TVLCP***QHRILPVPQRQMASFFPVHRSPRTL
SDFLLLKRLRALSAAQGALLHRLKVPVICQA*LR
RRIQTVPVGRKIKAWKEKGKRWSQHLLWTLELY
LIKTAAFRACLIVE*RARKAFRPVETEMKKLEQ
NLLECPQTRSP*AVEMLCFRETWSWSQAQPSIPL
EVNWEAFQQQMSVPQTLQGKWNMGS*TQMPLFG
RMCFREGKVQRKDLRTLILAQLEPLTCTSQVSL
WIKSVFQTVPLLPVPWMVTNLLSLHLHLVMKKPP
LKKQQKRKLHEVVRRVLMLQ*IRILW*FQLLQK
TRFQMD*NLILS*QQA*VRQCHPQI*PFLGWKK
M*CHTRTQKQIHLMLKAKRANPHPFVLQLETINF
VQTLHVNRTQ*LLVAIWLQNCVIT*LASPKAPQ
QGNPAHKIHPMPPTVKTHRLIQSPLTL*GIPRN
VRIFVLSKWWITKANEKM*N*INL*QICLRWFHI
HIQLSLKWRKNWCQTRQ*YQTVLSLWQTVQAVN
Q*PRMTHFLLSPPRKKREQQLLNYIQLQIIEMA
QMEIRMSLIRGH*KTGQ*ACPHPPLLQSFSTGWG
IPVSQDLVESMRVPPLQQSQKL*ISRGTLTLPC
KVWVRPLWL*IQF*LKKENFWWFQKALQLRNKI
RIKR*PVPLLRKMLSLQELCRKSREHHLLDKILN
NFMKNQSQLTVPRTKHFS*VIHRVHPLPFLRQK
LNITRKWPHKSHC*LKVGLPRAWCHQEQVWPQS
QGRKPWGQSTTAPLCCHVCCQMGLMGPMLLTAVS
LLLWMLE*RTLNPREKLVPVR*VEM*RWMLQGL
MLYKVWLSPEERIYHTTPKTS*FQTSC*AKRRM
PF*VCQWLYRTKL*LTHRELEPQR*YLLIGRKGS
WREQTTAVPWVTLRKPK*TMKHILSYCSLLPRS
SPQTWSSQPMMMGPQLV*GKSCEPRLQAGKGAL
PLYLAWSLPRTHLCLRGQT**RRLPAV*WMLSSN
KSRPLEHCLLRGRPVTCHCPALSWVLSLKD*RV
LLQKK*VLSHLGRAYQWAVLLRKPRGALQDVLL
EGRSQRRSFYLSRGLSQQQKCQT*KLKMKWILEQ
VQFLKKWL*GA*LLH*R*SKAQ*PRR*TEKTGV
Q*SHALMQHLFWLPSRAQNVRTSWMLDWAESVP
QNKVYLKENLGVILTSFTHPVMTWTASSSQSQRK
SIWPVISPDPVHPPMTRLHWTDILLMAVMCLSP
RF*SQTGQEIGKALMDSTAMGWELRVEKVRVSL
LTQATWRRRRWTVSLKCLQTALS*GAPCALFLPS
GGTAGGLGKMQPAMQK*TTGVQCEFLGMLSGDL
PFIGE
VSV*KA*QEELVSETSHPHL*K*ALQMP
KSSDTHSVVRNGLTLWCHFQKRIWSQTRENIGCL
ISRYVTDLSSRDLITVHQPFPLH*QNPSH**QS
AILDWTIHGPSTVPSTIPVLI*LRV*QKRTIIS
CHIAPPRKILNGRVEQKSVVHSATSRIKCLAARR
AKKRKKKKIRLRRRRKILKTRRKIRRLSTGTLS
VPFLLWVPSAVASV*SPSPTKMPILVQIAVLLS
TKAAEKV*PPVQRSK*SSPKGAFRHMTHHHCPRS
L*ETSPHSPRSVLGPQSSWWMKPLPPQYLPIDD
PSRVSRSPKVSPYRTLLELAMMRTCQTPGNSCL
IQQTH*IKSARSMSQQNHLLMRE*VQT*MKDNYW
ETLRLSPNSWKQSLGVG**TASF*NSKRKMWSN
GKK*YMS*CRQSFIMSALSRS*VVCTARG*WRI
CFLSSRW*KSCSPVWMS*SVSIANSSRGFWSGRR
SLWWIKVKRTFSSRG*GMCL*ISFQVRMQNV*R
RHMASFVGNITSL*TTSKTFMPRISVFKPL*RR
R*AVQLLEGLEFQSAYCL*LSGLPSTQFYSKEYC
SVPKTMKWSRKI*HSP*AW*RM*LEL*TAKWQV
MKRKCVSMRFIQRQIASQS*G*RVVRCLPRKI*
NGRSLYVMGVCF*RMQQEG*KRFKQFFSLTF*FS
FKKKTRSTSLHHWTRSQQ*SL*RS*L*EKWHMR
RKVYS*SAWG*QIQRW*KSMPAPKRNETAGFRS
FRTQSTP*TEMKMKEFLVRMRKKRKCWTPEPEN*
KNNFTRRTKKSYSCWKRRR*FSGTWLSAAPLSQ
RIAPQHIALEFSSAPTQKRLSKEDL**KVQ*MR
WRSFRVW*VEIWEAHLGRLSAAPLSKMWSVPFPC
PGEQRPLEDLTAIR*MLQKEARRKREMMAKILG
ERNQIVA*KRVEMLTWYLCLKETVSRLSRALFI
STSSSALCRVWCCSRTATLRTRNWC*ARGRSLAA
CPARAPSLSRRSSAAWRSSARTWPTCRSSRPST
SRRSAGASVSGKLVRGSCGSGRPSWPSARRRCS
RGSRTWKRSGRSSSRRRAHTSMTWSDCVLPRNSL
RGNRSSCAGRQSGSASGRQNGTCVRFPIHIPS*
*GSHRSSPVLRSPPRHLHLP*PNQGHWTQNFQC
PQKGTASLGHTKIRGLFTY*VQPARQTKDQKGRA
RPLRPPLPLPACLG*QSQRKRRRKKRRTKPAAL
SPVMVPRQKYQQRVKRSSADPLPLC*GSCLLIL
ASPPLLLSPRAQVSYTGRPLLLSVQSSWAAPGPG
Q*ATDDIECRVGKEAQTLLRP*FVTAQDSQVGL
ALLRITLKVMAS*VQVMVLDTSGIPKG*KSVSK
*GLNLRMPFIWGNTKPNSRCFGLDLCTYMGTCLH
IHTGNARRRPSLHQASGQLSTRAVPGRTRSPRI
SAVHPVLLRDWFPSKPIPGTYHPCFACISHFIL
GMTNICETSERRLDVYKRRDVHHLDLGVSGTKAT
KQPIVSHSVIRSRRNILVFQHVYPHVLAMDKVK
RPTHHYPCSVTPFDCH*PLRRGHGLLAVFLSPR
RASPRQQLSGPCWVRAHHCQGSASHPGQAEAVL*
S*DSWLRSGFRRRVKPCVAVPASADLERSWPGR
RGCESALLMLGGLGKIGFLQKYM*RSVVELYSA
PGSRYRWLPAARLCFCFSHRVFIFVHLRLSPAGV
CRTVHGNVAL*GPVHQKGGPGKFCASNVAFNSC
FFAPRKHGAFEHT*KKKNL*LGAY**IASWPCR
WRYLSFSLFERGLV*NL*PTFVLFIVFVCLCLFF
FKGEPGLAQQSKLSSQYRVKWQPALFTLCLLKC
LEGPDEILKGGGPCPSLPHPASFFNQRMSSPLF
ENEETRHL*PTFAFFCHGEYSPFRNRPKAKTC*F
FY*KYVPLQRP*TKS*VSFFHLFVQLQVTAESV
VTFLRSTRGLAVCSGHWLRVPLLGFAGGQY*TC
ILLLVNVGRVPLFSGFGTIRGWC*WDLLAYVLFT
KTPWMLKLEHVATELDINVRGSLTPRPAVMFHL
LWLFWWSFLKIEISHLPRPHSKRFGQVLVGQV*
NQSSARNSLKPPNFIQEYSLQCSNRTAYQELCLH
TFVISLPPLEVVLRGICSCPGDLPGMVAACAFA
HGLDSALVAGSNGLSWFLSHEKGLFFWGDSD*I
PHTVSTPGHHVLHQAKEITCLKLCLSFGGKMEFL
SRAPRFPESSELPGRRLRLLSIPVISVVVVR*H
VHFKCSHRLASFSRQSNVLTVFSS*KMERVKNM
QTATFNLCQYSLYPRESYLGGRILTKVFLERYES
*LFSPSVSQGNTIQSRPFAHFLPYLLPS*GLSI
SREHKVLRPLALFLDVGGEVLVHARVELDRPCL
SRGWDYNLRGQNLIQKLLSTEVLSISSFLFLGLF
FCSQVFPRILVFALELRFTLMMVAQLCPEDSQA
GPGREFRKTVLVNGLQVVTKRVAVR*PQTLQND
VHPLRFGCPWNVGA*K*PCGWNWGSGCWRSVCLA
FLQQDRLGAQPPMDASQPAPSLSSILRDKEEGR
EFGLGFELSFQCSKAFLVNQSLGIYCLLARL*N
EKCFNAAIKGRRGGGRENKGIFPSTHLI*LSKD*
*AMNYFSISLRVKGVQPPTGCVPCHRSE*PALQ
PGGTTCAAVRRGFCRKHSPPTPSPA*ASPTFRH
HLRA*AQAMGRAW*VCLWFRLSLWSPVCCCPHGM
RRGGVGIRRRVVGIHRIPLLSLLVCKCSMDICV
LNPIK*KRRVKTQMLYIHL*LCIK*SSFKL*RF
FSVCFLEFCHNILASYFIYLSF*LPASDPCKVSL
SPFKK**ISCEVL

Frame 1

ELKWGK*RSKSFHDVWLSAAAQVTTSTQRKGGF
WRQGGEETVGGHFPEQPLPATLL*SLCRRAAAA
VNLSLP*QPECPVQEPYYWSHAARWAVLPCNPSS
QFLLRVYSREDSQALPPSRVPRPPSRASFGACA
DWSCVQGQRGARAAAVKRLCSAETAVPIARLGR
RRFSRLRGSGRLLSFSAAKVKSCPSSARGGAPGA
ARVLGHET*STASSLIW*LCCYSAAC*RGQS*R
*CSVLLGIFGFHPPSLYKYSEGQF*YIGDHCSW
S*LL*NSEGAALCFQRGPSRVCGG*RRLSFRPG*
SV*CSSIPSNQCWKSAGFELYPFS*PVRTPIWG
CEFP**EVGAGIQAPEAAHGVECIGDRSEFA*C
WPARDIDAFCCAAGTAEVDVVPVAEARWPRSSQY
PQPGRGDACELGLGARLSQAAPASNRGECWRTR
LLEQFIL*NTVWRLFCEASSRVGHLYINL*V*F
TS*TPISWRRLHWTNF*TYEHPTATNENKPQADG
QSYALNDDSTGSFQCPRDRWPVSSLCTGAHGPS
ATFFF*RD*EHSVLPREPCCTD*KSL*FVKHS*
GGEYRPFL*EEK*RRGKKRGRGGASTYCGLWNCI
*SRQLPSELA*LWSKGHGRPFVLWKQK*RNWNK
IFWNAHRPGVPEQWRCCASERLGHGARHSPVFL
WR*TGRHFNNKCQYPRHCRGNGTWAHEPRCHCLE
ECASGRGKYKGKI*EL*YWHSWSL*RARHK*AC
G*NQCSKLCPCCQFPGW*QTC*VFTCI***RNL
H*KNSRNGNFTKS*GEC*CSSRSEFCGDSSCCKR
QDFRWIRTLYSLSSRHR*GNVTLRFSPSWAGRR
CNATPELRNKFISCSKPKGQILTHLFYNWRR*T
LCRLCMSTEHSDF*WRFGCKTV**HS*RVRKHHS
KATQLTRSTRCLPL*RPTGSYSHL*PCKGYPGT
CGFLSFQSGG*QRPTKRCETR*TFNKYA*GGFT
STSSCP*NGERTGARPGSNIRQYFLSGKQSRQ*I
SNQG*RTFFCPLPERKGNSNS*TTYSYRL*RWP
RWKFE*A*YAATRRQGSRPVHILHCCRASARDG
EYQSHRTWWRA*GSRPSSNPRSSEYQGEH*LFPA
KCG*GHFGFRFSFD*RRKTSGGFRKLCSSGTR*
G*SGDLFLY*GKCSLFRNFAGRAENTTSWTRYS
TIS*KINLS*LCQGQSTSAK*FTGCILCLS*GRN
*T*QGSGPTSLTADSRWGCPEPGATRSKSGHRV
KAGSLGGRAQQLRSVAMSVARWV*WVRCS*LQS
AFSSGCWSEEHSIPGKN*CL*GEWRCDGGCYRG*
CSTRYG*AQKREYITQHPRHPDSKRLVEPREEC
RSRFASGSTGQSCD*PTGSWNPRDDTS*LGERE
AGGSRPQLYHG*R*GSPNRR*STSCPTAACCQGA
PHRHGALSP**WGPSWCEGSHASPAFRQGKEHS
LSTLHGLCPGRTSA*GGRLDRGGCQPYSGCCHR
TSQGRWSTAY*GGGLSHVTVQP*VGSSH*RTREC
FYRKSEYFPTWGEPTNGQYS*GSHGEPCRMFCW
KGGAREDHFTCPGA*ASSRNARRES*R*SGF*S
KFNF*RSGCREHSCYTEDEARPNDPGDKPRKLVY
NRAMP*CSISSGFQAEPRM*ELPGCWTGQRVYL
KTRCT*KRIWE*F*PLSLTQ**HGQHHLPKARG
RAFGL*YHRIQFIHR*HGFTGPTFFSWQ*CVSLP
DFKAKQVKRSAKP*WILQPWDGS*GSRK*E*AC
*PRRRGGGGDGQYH*SACKLLCPKELHALSFSL
PEAQLGAWEKCSQRCRNEPPEFNASSWGCCQETS
HS*EK
FQSRRLDRRSWCRKQAILISRSKLCKCR
RAQTPIQW*GTG*LFGVTFRRGSGVRPERT*DV
*SADMSQI*AAGI*LLYISHFLSIDKIHLINDNQ
PSWIGQFTALPQYLPQYQC*SD*EYNRREL*FP
AT*PLQERF*MEEWNKSQSYIQLHQE*NV*QQE
EQRKGKRKR*D*GEGERF*RQGER*EDCQRAHFQ
FHSCCGSHQL*PVYEALHQQRCLYLCKLQCFCP
QRLPRKSSLLCKGQNEAAQREPSGT*HIITAHG
HYEKQALTAQGASSVRSPPGG*NRYHPNICQ*TI
PAECLALQKCLHTEHYWSWQ**EHVKHLEIPVS
FNRLTK*NQQGQ*VNRITY**GSRYRHE*RTTT
GRL*D*VQTAGSRVLESDNRQQVSKTAKERCGQT
ARSNI*VDADRVSSCPHSQDHEWCVQPGDDGGS
AF*AADGRKAVPLFG*ADQYP*PILPEDSGAEE
GVSGG*K*KELSHQEDRGCACKSVFR*ECRTFKE
DIWQVLWAT*PVCKLLQRPLCQG*AFSSLCKEE
DEQFSC*KAWNSRVHIACNSADYQVPSFIPKNI
AVYQRQ*SGAGRSSTVLEPGEGCDWSCRQQSGKL
*KESASQ*DLYKDR*QVNHEDEEWSDVCQGRFE
TEEACT*WECVSEECSRKVERGSSSSSH*HFSF
PSRKRPEVHLCIIGPEVNSDLFKEADCERSGT*G
ERFIPDQHGDDRSRDGRSPCQLQRGTKQLDSDH
SGHNQHPEQR*R*RNS**E*GRKENVGHQSPRI
KRTTSPEGPKNPTLVGREGDDFPGHG*VQHPSPR
GLLPNT*P*SSLPLQHRRGSQRRTFNEKCNK*G
GDPSGFGEWKSGRHTWADCQQPH*ARCGRSRFP
APESRDLWRI*QPSDECFKRRREGRGR*WPRS*E
NGIR*WPKKGWKC*PGIYA*KKQ*AGCPERCSS
LRAPQRSAGCGAAAGQLH*GPETGAEREGAHSQ
LVPPELPH*AGEAAQPGEAAPGPGQPAEAAGPVP
RGEAQARA*VGSS*EGAAGAGGPPGPARGGGAA
GAAGPGKGAGGAPAEEGHIPV*PGATACCPETA
*EGTGAAAPGGRAAQPAADRTGPVSGFPSTYQAD
EDPIVLPQS*GAPLAICTFHSQIRVIGLRTFSV
PKKEQHLSDTQR*GAFSHTEFNQPDKQRTRRAE
PGPCVHLCLYPPVWVNKAKGKEGEKKEEQNQPLS
AR*WSRVRSISRG*RDLLLTLFLSAEAAAS*SW
PAHLSCCPRVHKSLTLDAHCSSASSPPGRPQVL
DNKQQMILSVGWGRRPRLCFGHDL*LPRTLRLGW
PYSGLH*K*WPRKYR*WFWTRQEFLKAERVYPS
KV*TSECLLFGGTQNQTADVLDLICVRTWGPVC
IYTRGMPEEGPVCTRRLVNLAQGQCLDGPGAPAY
QQFTQYSSETGFPLNPSRAHTTRVLHVFLISF*
G*QTFVKPVREGLMCIKDVMCTTSISVFQALKQ
QNNP*YLILSSDPEEISWFSSMFTHMFWPWIK*R
GLLTIIPAA*HLLIVTDHSEGATASWLCS*APV
VPLPDSSCLALAG*GHTTARGQPRTQARQKLCS
EARTAG*EVGSGEG*SHV*QFLPVQIWRGAGPEG
VVVKAPFLC*EALAKLDFFKNTCKGLLLNCTLP
LEADTDGCLLLGFAFAFPTVFSSLFT*GFPQLV
CAGQFMVMLPSEAPYTRREALENFVLPTWPSILA
FLPLGSMGLLSTLKKRKICNLVLIDELQAGLAD
GDIYLSVYLKEVWFKICSLHLFYLLYLCVCVCF
FLRVSQV*PNSLNYPVNTE*SGSQHCSLCVF*SA
LKAQMKF*REGVHVLPSPTPPHSLIKGCLLPCL
RMKKLATSDLPLPFSVMENTHPSETDQRPKPAD
FSIENMSPCKDPKQKVKFLSFTYLYNSKLQLNLS
*LS*DLPGAWLSVLGTGSEFPSWDLQEGSTEPA
FFSL*M*AGCPCSPGLEQYEVGADGIYLRTCSS
QKHRGC*S*STSPQSLTSMLEGLLLPAQL*CFIC
FGCFGGLF*K*RFHICPDPTQNDLVRFWLDKFK
IKVVPGIPSNHPTSSRNTVCSAATEPLTKNCAY
IPLSSLFPPWKLSSGGFVPVLGIYLGWWLPVLLL
MALTVL*LLDLMACLGFYHMRRGCFFGVTRTEF
PILFPRRDTMFSIKLKKSRA*NCA*VLGERWSS
YPEPPDFQNRVSFLEGDCVFSQFQSSQSLSLGDM
CTLNALIGWLHFQDNQMY*LCFLLRKWRGLKTC
KLPLSTFASIPSTPVRAIWGEESLPRFFWKGTN
LNFFPLLCLRVILFRVAPLLIFSRICYLPEASVL
VVSTKF*DLWRCFLMWEGRC*CMQGLN*IDPAL
VEGGTITLEART*SRSCCPQKCFLFHHFCF*GS
FSVARSSQGF*YLHWS*GLL**WWPSCAQRTARQ
ALGGSLERQSW*MGFKWSQRGWL*GDPRHCRTM
CTLCVLDVLGMWEPRNNPVDGIGAAAAGDLCAL
PSFSRTV*VRSHLWMRPSQPRRSRPSSETKKRAG
SLGLVLNFPFNVAKHS*LTRALESTACWPGFKM
KSVLMLP*KGGGGEEGKIKASFQVLI*FNCQKI
DRP*ITSPSH*GLKACNPPLAVSPATEVSDLPYN
QVGPPVLQSGGASAGSTHPPHLPRPELPLPFVT
T*GHEHRPWGVPGESACGSGLACGLLCAAARMG
CAGEAWGSAGGWLGYTGYLCSHCLFANALWTFVC
*ILLNKKDGLKPRCCIFICNYV*SEAVLNCKDF
FQCVFSNFATTYWLRILFIFLSSYQLQTLVKSP
SALSKNNKFPVKFW

Frame 2

S*SGGNRGVNHFTMCG*VLQLR*PPVHRGRAVS
GDRAERRPWVGISQSSLCQPPYFDHFAAEQQRR
STSASLSNLSAPSRSLTIGLMQRDGQFCRAIPA
RSSCSACTHGRTRRRYRLPACPAHPPERLSAHAR
TGAVCRASAEPEQPR*SACALPRLPCPLLASVA
AALAASGGAAAYCLSPRRR*RVVPARPAGEPRE
PHVSWVMKLNPQQAPLYGDCVVTVLLAEEDKAED
DVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPG
HDCCETVKVQLCASKEGLPVFVVAEEDFHFVQD
EAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGD
VNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDA
GPRETLMHFAVRLGLLRLTWFLLQKPGGRGALS
IHNQEGATPVSLALERGYHKLHQLLTEENAGEPD
SWSSLSYEIPYGDCSVRHHRELDIYTLTSESDS
HHEHPFPGDGCTGPIFKLMNIQQQLMKTNLKQM
DSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQ
RLSSSEETESTQCCPGSPVAQTESPCDLSSIVE
EENTDRSCRKKNKGVERKGEEVEPAPIVDSGTV
SDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTK
SSGMPTDQESLSSGDAVLQRDLVMEPGTAQYSS
GGELGGISTTNVSTPDTAGEMEHGLMNPDATVW
KNVLQGGESTKERFENSNIGTAGASDVHVTSKPV
DKISVPNCAPAASSLDGNKPAESSLAFSNEETS
TEKTAETETSRSREESADAPVDQNSVVIPAAAK
DKISDGLEPYTLLAAGIGEAMSPSDLALLGLEED
VMPHQNSETNSSHAQSQKGKSSPICSTTGDDKL
CADSACQQNTVTSSGDLVAKLCDNIVSESESTT
ARQPSSQDPPDASHCEDPQAHTVTSDPVRDTQER
ADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSH
PHPVVPKMEKELVPDQAVISDSTFSLANSPGSE
SVTKDDALSFVPSQKEKGTATPELHTATDYRDGP
DGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMG
NTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSL
QSVGKATLALDSVLTEEGKLLVVSESSAAQEQDK
DKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQ
QFHEKSISADCAKDKALQLSNSPGASSAFLKAE
TEHNKEVAPQVSLLTQGGAAQSLVPPGASLATES
RQEALGAEHNSSALLPCLLPDGSDGSDALNCSQ
PSPLDVGVKNTQSQGKTSACEVSGDVTVDVTGV
NALQGMAEPRRENISHNTQDILIPNVLLSQEKNA
VLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGK
LEGADHSCTMGDAEEAQIDDEAHPVLLQPVAKE
LPTDMELSAHDDGAPAGVREVMRAPPSGRERSTP
SLPCMVSAQDAPLPKGADLIEEAASRIVDAVIE
QVKAAGALLTEGEACHMSLSSPELGPLTKGLES
AFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAG
REEPEKIILPVQGPEPAAEMPDVKAEDEVDFRA
SSISEEVAVGSIAATLKMKQGPMTQAINRENWC
TIEPCPDAASLLASKQSPECENFLDVGLGRECTS
KQGVLKRESGSDSDLFHSPSDDMDSIIFPKPEE
EHLACDITGSSSSTDDTASLDRHSSHGSDVSLS
QILKPNRSRDRQSLDGFYSHGMGAEGRESESEPA
DPGDVEEEEMDSITEVPANCSVLRSSMRSLSPF
RRHSWGPGKNAASDAEMNHRSSMRVLGDVVRRP
PIHRRS
FSLEGLTGGAGVGNKPSSSLEVSSANAE
ELRHPFSGEERVDSLVSLSEEDLESDQREHRMF
DQQICHRSKQQGFNYCTSAISSPLTKSISLMTI
SHPGLDNSRPFHSTFHNTSANLTESITEENYNFL
PHSPSKKDSEWKSGTKVSRTFSYIKNKMSSSKK
SKEKEKEKDKIKEKEKDSKDKEKDKKTVNGHTF
SSIPVVGPISCSQCMKPFTNKDAYTCANCSAFVH
KGCRESLASCAKVKMKQPKGSLQAHDTSSLPTV
IMRNKPSQPKERPRSAVLLVDETATTPIFANRR
SQQSVSLSKSVSIQNITGVGNDENMSNTWKFLSH
STDSLNKISKVNESTESLTDEGVGTDMNEGQLL
GDFEIESKQLEAESWSRIIDSKFLKQQKKDVVK
RQEVIYELMQTEFHHVRTLKIMSGVYSQGMMADL
LFEQQMVEKLFPCLDELISIHSQFFQRILERKK
ESLVDKSEKNFLIKRIGDVLVNQFSGENAERLK
KTYGKFCGQHNQSVNYFKDLYAKDKRFQAFVKKK
MSSSVVRRLGIPECILLVTQRITKYPVLFQRIL
QCTKDNEVEQEDLAQSLSLVKDVIGAVDSKVAS
YEKKVRLNEIYTKTDSKSIMRMKSGQMFAKEDLK
RKKLVRDGSVFLKNAAGRLKEVQAVLLTDILVF
LQEKDQKYIFASLDQKSTVISLKKLIVREVAHE
EKGLFLISMGMTDPEMVEVHASSKEERNSWIQII
QDTINTLNRDEDEGIPSENEEEKKMLDTRAREL
KEQLHQKDQKILLLLEEKEMIFRDMAECSTPLP
EDCSPTHSPRVLFRSNTEEALKGGPLMKSAINEV
EILQGLVSGNLGGTLGPTVSSPIEQDVVGPVSL
PRRAETFGGFDSHQMNASKGGEKEEGDDGQDLR
RTESDSGLKKGGNANLVFMLKRNSEQVVQSVVHL
YELLSALQGVVLQQDSYIEDQKLVLSERALTRS
LSRPSSLIEQEKQRSLEKQRQDLANLQKQQAQY
LEEKRRREREWEARERELREREALLAQREEEVQQ
GQQDLEKEREELQQKKGTYQYDLERLRAAQKQL
EREQEQLRREAERLSQRQTERDLCQVSHPHTKL
MRIPSFFPSPEEPPSPSAPSIAKSGSLDSELSVS
PKRNSISRTHKDKGPFHILSSTSQTNKGPEGQS
QAPASTSASTRLFGLTKPKEKKEKKKKNKTSRS
QPGDGPASEVSAEGEEIFC*PSSSLLRQLPPDPG
QPTSPAVPACTSLLHWTPTAPQRPVLLGGPRSW
TISNR*Y*VSGGEGGPDSASAMICDCPGLSGWA
GPTQDYTESNGLVSTGDGFGHVRNS*RLKECIQV
RSEPPNAFYLGEHKTKQQMFWT*SVYVHGDLSA
YTHGECQKKAQSAPGVWST*HKGSAWTDPEPPH
ISSSPSTPQRLVSL*THPGHIPPVFCMYFSFHFR
DDKHL*NQ*EKA*CV*KT*CAPPRSRCFRH*SN
KTTHSISFCHQIQKKYPGFPACLPTCFGHG*SE
EAYSPLSLQRDTF*LSLTTQKGPRPPGCVPEPPS
CLSQTAAVWPLLGEGTPLPGVSLAPRPGRSCAL
KLGQLAEKWVQAKGEAMCSSSCQCRSGEELARK
AWL*KRPSYVRRPWQNWISSKIHVKVCC*IVLCP
WKQIQMAACCSALLLLFPPCFHLCSLEAFPSWC
VQDSSW*CCPLRPRTPEGRPWKILCFQRGLQFL
LFCPSEAWGF*AHLKKEKSVTWCLLMNCKLALQM
EIFIFQFI*KRSGLKFVAYICFIYCICVFVFVF
F*G*ARSSPTV*TIQSIPSEVAASTVHSVSFEV
P*RPR*NFKGRGSMSFPPPPRLIL*SKDVFSLV*
E*RNSPPLTYLCLFLSWRILTLQKQTKGQNLLI
FLLKICPLAKTLNKKLSFFLSPICTTPSYS*IC
RDFPEIYPGLGCLFWALAPSSPPGICRRAVLNLH
SSPCKCRPGAPVLRVWNNTRLVLMGFTCVRALH
KNTVDAEVRARRHRA*HQC*RVSYSPPSCDVSS
ALVVLVVFFKNRDFTSAQTPLKTIWSGSGWTSLK
SK*CPEFPQTTQLHPGIQSAVQQQNRLPRTVLT
YLCHLSSPLGSCPQGDLFLSWGFTWDGGCLCFC
SWP*QCSSCWI*WPVLVSIT*EGVVFLG*LGLNS
PYCFHAGTPCSPSS*RNHVPETVLKFWGKDGVP
IQSPQISRIE*ASWKETASSLNSSHLSRCR*VT
CAL*MLSSVGFIFKTIKCIDCVFFLENGEG*KHA
NCHFQPLPVFPLPP*ELSGGKNPYQGFFGKVRI
LTFFPFCVSG*YYSESPLCSFSPVFVTFLRPQY
*S*AQSFETFGVVS*CGRGGVSACKG*TR*TLP*
*RVGL*P*RPELDPEVAVHRSAFYFIIFVSRAL
FL*PGLPKDFSICIGVEVYSNDGGPAVPRGQPG
RPWEGV*KDSPGEWASSGHKEGGCEVTPDTAERC
APSAFWMSLECGSLEITLWMELGQRLLEICVPC
LPSAGPSRCAATYGCVPASPVALVHPQRQRRGQ
GVWAWF*TFLSM*QSIPS*PEPWNLLPAGQALK*
KVF*CCHKREAGGRKGK*RHLSKYSSNLIVKRL
IGHELLLHLTKG*RRATPHWLCPLPPK*VTCPT
TRWDHLCCSPEGLLQEALTPHTFPGLSFPYLSSP
PEGMSTGHGACLVSLPVVQA*PVVSCVLLPAWD
AQGRRGDPQEGGWDTPDTSALIACLQMLYGHLC
AKSY*IKKTG*NPDAVYSFVIMYKVKQF*TVKIF
FSVFSRILPQHTGFVFYLSFFLVTSFRPL*SLP
QPFQKIINFL*SS

Sequence AKAP13.aAug05

TGAGTTGAAGTGGGGGAAATAGAGGAGTAAATCATTTCACGATGTGTGGTTAAGTGCTGCAGCTCAGGTAACCACCAGTACACAGAGGAAGGGCGGTTTC
TGGAGACAGGGCGGAGAGGAGACCGTGGGTGGGCATTTCCCAGAGCAGCCTCTGCCAGCCACCCTACTTTGATCACTTTGCCGCCGAGCAGCAGCGGCGG
TCAACCTCAGCCTCCCTTAGCAACCTGAGTGCCCCGTCCAGGAGCCTTACTATTGGTCTCATGCAGCGAGATGGGCAGTTCTGCCGTGCAATCCCAGCTC
GCAGTTCTTGCTCCGCGTGTACTCACGGGAGGACTCGCAGGCGTTACCGCCTTCCCGCGTGCCCCGCCCACCCTCCCGAGCGTCTTTCGGCGCATGCGCG
GACTGGAGCTGTGTGCAGGGCCAGCGCGGAGCCCGAGCAGCCGCGGTGAAGCGCCTGTGCTCTGCCGAGACTGCCGTGCCCATTGCTCGCCTCGGTCGCC
GCCGCTTTAGCCGCCTCCGGGGGAGCGGCCGCCTATTGTCTTTCTCCGCGGCGAAGGTGAAGAGTTGTCCCAGCTCGGCCCGCGGGGGAGCCCCGGGAGC
CGCACGTGTCCTGGGTCATGAAACTTAATCCACAGCAAGCTCCCTTATATGGTGATTGTGTTGTTACAGTGCTGCTTGCTGAAGAGGACAAAGCTGAAGA
TGATGTAGTGTTTTACTTGGTATTTTTGGGTTCCACCCTCCGTCACTGTACAAGTACTCGGAAGGTCAGTTCTGATACATTGGAGACCATTGCTCCTGGT
CATGATTGTTGTGAAACAGTGAAGGTGCAGCTCTGTGCTTCCAAAGAGGGCCTTCCCGTGTTTGTGGTGGCTGAAGAAGACTTTCATTTCGTCCAGGATG
AAGCGTATGATGCAGCTCAATTCCTAGCAACCAGTGCTGGAAATCAGCAGGCTTTGAACTTTACCCGTTTTCTTGACCAGTCAGGACCCCCATCTGGGGA
TGTGAATTCCCTTGATAAGAAGTTGGTGCTGGCATTCAGGCACCTGAAGCTGCCCACGGAGTGGAATGTATTGGGGACAGATCAGAGTTTGCATGATGCT
GGCCCGCGAGAGACATTGATGCATTTTGCTGTGCGGCTGGGACTGCTGAGGTTGACGTGGTTCCTGTTGCAGAAGCCAGGTGGCCGCGGAGCTCTCAGTA
TCCACAACCAGGAAGGGGCGACGCCTGTGAGCTTGGCCTTGGAGCGAGGCTATCACAAGCTGCACCAGCTTCTAACCGAGGAGAATGCTGGAGAACCAGA
CTCCTGGAGCAGTTTATCCTATGAAATACCGTATGGAGACTGTTCTGTGAGGCATCATCGAGAGTTGGACATCTATACATTAACCTCTGAGTCTGATTCA
CATCATGAACACCCATTTCCTGGAGACGGTTGCACTGGACCAATTTTTAAACTTATGAACATCCAACAGCAACTAATGAAAACAAACCTCAAGCAGATGG
ACAGTCTTATGCCCTTAATGATGACAGCACAGGATCCTTCCAGTGCCCCAGAGACAGATGGCCAGTTTCTTCCCTGTGCACCGGAGCCCACGGACCCTCA
GCGACTTTCTTCTTCTGAAGAGACTGAGAGCACTCAGTGCTGCCCAGGGAGCCCTGTTGCACAGACTGAAAGTCCCTGTGATTTGTCAAGCATAGTTGAG
GAGGAGAATACAGACCGTTCCTGTAGGAAGAAAAATAAAGGCGTGGAAAGAAAAGGGGAAGAGGTGGAGCCAGCACCTATTGTGGACTCTGGAACTGTAT
CTGATCAAGACAGCTGCCTTCAGAGCTTGCCTGATTGTGGAGTAAAGGGCACGGAAGGCCTTTCGTCCTGTGGAAACAGAAATGAAGAAACTGGAACAAA
ATCTTCTGGAATGCCCACAGACCAGGAGTCCCTGAGCAGTGGAGATGCTGTGCTTCAGAGAGACTTGGTCATGGAGCCAGGCACAGCCCAGTATTCCTCT
GGAGGTGAACTGGGAGGCATTTCAACAACAAATGTCAGTACCCCAGACACTGCAGGGGAAATGGAACATGGGCTCATGAACCCAGATGCCACTGTTTGGA
AGAATGTGCTTCAGGGAGGGGAAAGTACAAAGGAAAGATTTGAGAACTCTAATATTGGCACAGCTGGAGCCTCTGACGTGCACGTCACAAGTAAGCCTGT
GGATAAAATCAGTGTTCCAAACTGTGCCCCTGCTGCCAGTTCCCTGGATGGTAACAAACCTGCTGAGTCTTCACTTGCATTTAGTAATGAAGAAACCTCC
ACTGAAAAAACAGCAGAAACGGAAACTTCACGAAGTCGTGAGGAGAGTGCTGATGCTCCAGTAGATCAGAATTCTGTGGTGATTCCAGCTGCTGCAAAAG
ACAAGATTTCAGATGGATTAGAACCTTATACTCTCTTAGCAGCAGGCATAGGTGAGGCAATGTCACCCTCAGATTTAGCCCTTCTTGGGCTGGAAGAAGA
TGTAATGCCACACCAGAACTCAGAAACAAATTCATCTCATGCTCAAAGCCAAAAGGGCAAATCCTCACCCATTTGTTCTACAACTGGAGACGATAAACTT
TGTGCAGACTCTGCATGTCAACAGAACACAGTGACTTCTAGTGGCGATTTGGTTGCAAAACTGTGTGATAACATAGTTAGCGAGTCCGAAAGCACCACAG
CAAGGCAACCCAGCTCACAAGATCCACCCGATGCCTCCCACTGTGAAGACCCACAGGCTCATACAGTCACCTCTGACCCTGTAAGGGATACCCAGGAACG
TGCGGATTTTTGTCCTTTCAAAGTGGTGGATAACAAAGGCCAACGAAAAGATGTGAAACTAGATAAACCTTTAACAAATATGCTTGAGGTGGTTTCACAT
CCACATCCAGTTGTCCCTAAAATGGAGAAAGAACTGGTGCCAGACCAGGCAGTAATATCAGACAGTACTTTCTCTCTGGCAAACAGTCCAGGCAGTGAAT
CAGTAACCAAGGATGACGCACTTTCTTTTGTCCCCTCCCAGAAAGAAAAGGGAACAGCAACTCCTGAACTACATACAGCTACAGATTATAGAGATGGCCC
AGATGGAAATTCGAATGAGCCTGATACGCGGCCACTAGAAGACAGGGCAGTAGGCCTGTCCACATCCTCCACTGCTGCAGAGCTTCAGCACGGGATGGGG
AATACCAGTCTCACAGGACTTGGTGGAGAGCATGAGGGTCCCGCCCCTCCAGCAATCCCAGAAGCTCTGAATATCAAGGGGAACACTGACTCTTCCCTGC
AAAGTGTGGGTAAGGCCACTTTGGCTTTAGATTCAGTTTTGACTGAAGAAGGAAAACTTCTGGTGGTTTCAGAAAGCTCTGCAGCTCAGGAACAAGATAA
GGATAAAGCGGTGACCTGTTCCTCTATTAAGGAAAATGCTCTCTCTTCAGGAACTTTGCAGGAAGAGCAGAGAACACCACCTCCTGGACAAGATACTCAA
CAATTTCATGAAAAATCAATCTCAGCTGACTGTGCCAAGGACAAAGCACTTCAGCTAAGTAATTCACCGGGTGCATCCTCTGCCTTTCTTAAGGCAGAAA
CTGAACATAACAAGGAAGTGGCCCCACAAGTCTCACTGCTGACTCAAGGTGGGGCTGCCCAGAGCCTGGTGCCACCAGGAGCAAGTCTGGCCACAGAGTC
AAGGCAGGAAGCCTTGGGGGCAGAGCACAACAGCTCCGCTCTGTTGCCATGTCTGTTGCCAGATGGGTCTGATGGGTCCGATGCTCTTAACTGCAGTCAG
CCTTCTCCTCTGGATGTTGGAGTGAAGAACACTCAATCCCAGGGAAAAACTAGTGCCTGTGAGGTGAGTGGAGATGTGACGGTGGATGTTACAGGGGTTA
ATGCTCTACAAGGTATGGCTGAGCCCAGAAGAGAGAATATATCACACAACACCCAAGACATCCTGATTCCAAACGTCTTGTTGAGCCAAGAGAAGAATGC
CGTTCTAGGTTTGCCAGTGGCTCTACAGGACAAAGCTGTGACTGACCCACAGGGAGTTGGAACCCCAGAGATGATACCTCTTGATTGGGAGAAAGGGAAG
CTGGAGGGAGCAGACCACAGCTGTACCATGGGTGACGCTGAGGAAGCCCAAATAGACGATGAAGCACATCCTGTCCTACTGCAGCCTGTTGCCAAGGAGC
TCCCCACAGACATGGAGCTCTCAGCCCATGATGATGGGGCCCCAGCTGGTGTGAGGGAAGTCATGCGAGCCCCGCCTTCAGGCAGGGAAAGGAGCACTCC
CTCTCTACCTTGCATGGTCTCTGCCCAGGACGCACCTCTGCCTAAGGGGGCAGACTTGATAGAGGAGGCTGCCAGCCGTATAGTGGATGCTGTCATCGAA
CAAGTCAAGGCCGCTGGAGCACTGCTTACTGAGGGGGAGGCCTGTCACATGTCACTGTCCAGCCCTGAGTTGGGTCCTCTCACTAAAGGACTAGAGAGTG
CTTTTACAGAAAAAGTGAGTACTTTCCCACCTGGGGAGAGCCTACCAATGGGCAGTACTCCTGAGGAAGCCACGGGGAGCCTTGCAGGATGTTTTGCTGG
AAGGGAGGAGCCAGAGAAGATCATTTTACCTGTCCAGGGGCCTGAGCCAGCAGCAGAAATGCCAGACGTGAAAGCTGAAGATGAAGTGGATTTTAGAGCA
AGTTCAATTTCTGAAGAAGTGGCTGTAGGGAGCATAGCTGCTACACTGAAGATGAAGCAAGGCCCAATGACCCAGGCGATAAACCGAGAAAACTGGTGTA
CAATAGAGCCATGCCCTGATGCAGCATCTCTTCTGGCTTCCAAGCAGAGCCCAGAATGTGAGAACTTCCTGGATGTTGGACTGGGCAGAGAGTGTACCTC
AAAACAAGGTGTACTTAAAAGAGAATCTGGGAGTGATTCTGACCTCTTTCACTCACCCAGTGATGACATGGACAGCATCATCTTCCCAAAGCCAGAGGAA
GAGCATTTGGCCTGTGATATCACCGGATCCAGTTCATCCACCGATGACACGGCTTCACTGGACCGACATTCTTCTCATGGCAGTGATGTGTCTCTCTCCC
AGATTTTAAAGCCAAACAGGTCAAGAGATCGGCAAAGCCTTGATGGATTCTACAGCCATGGGATGGGAGCTGAGGGTCGAGAAAGTGAGAGTGAGCCTGC
TGACCCAGGCGACGTGGAGGAGGAGGAGATGGACAGTATCACTGAAGTGCCTGCAAACTGCTCTGTCCTAAGGAGCTCCATGCGCTCTCTTTCTCCCTTC
CGGAGGCACAGCTGGGGGCCTGGGAAAAATGCAGCCAGCGATGCAGAAATGAACCACCGGAGTATGAGCTGGTGCCCCTCTGGTGTGCAGTACTCTGCTG
GCCTGAGTGCTGACTTTAATTACAGAAG
TTTCAGTCTAGAAGGCTTGACAGGAGGAGCTGGTGTCGGAAACAAGCCATCCTCATCTCTAGAAGTAAGCTC
TGCAAATGCCGAAGAGCTCAGACACCCATTCAGTGGTGAGGAACGGGTTGACTCTTTGGTGTCACTTTCAGAAGAGGATCTGGAGTCAGACCAGAGAGAA
C
ATAGGATGTTTGATCAGCAGATATGTCACAGATCTAAGCAGCAGGGATTTAATTACTGTACATCAGCCATTTCCTCTCCATTGACAAAATCCATCTCAT
TAATGACAATCAGCCATCCTGGATTGGACAATTCACGGCCCTTCCACAGTACCTTCCACAATACCAGTGCTAATCTGACTGAGAGTATAACAGAAGAGAA
CTATAATTTCCTGCCACATAGCCCCTCCAAGAAAGATTCTGAATGGAAGAGTGGAACAAAAGTCAGTCGTACATTCAGCTACATCAAGAATAAAATGTCT
AGCAGCAAGAAGAGCAAAGAAAAGGAAAAAGAAAAAGATAAGATTAAGGAGAAGGAGAAAGATTCTAAAGACAAGGAGAAAGATAAGAAGACTGTCAACG
GGCACACTTTCAGTTCCATTCCTGTTGTGGGTCCCATCAGCTGTAGCCAGTGTATGAAGCCCTTCACCAACAAAGATGCCTATACTTGTGCAAATTGCAG
TGCTTTTGTCCACAAAGGCTGCCGAGAAAGTCTAGCCTCCTGTGCAAAGGTCAAAATGAAGCAGCCCAAAGGGAGCCTTCAGGCACATGACACATCATCA
CTGCCCACGGTCATTATGAGAAACAAGCCCTCACAGCCCAAGGAGCGTCCTCGGTCCGCAGTCCTCCTGGTGGATGAAACCGCTACCACCCCAATATTTG
CCAATAGACGATCCCAGCAGAGTGTCTCGCTCTCCAAAAGTGTCTCCATACAGAACATTACTGGAGTTGGCAATGATGAGAACATGTCAAACACCTGGAA
ATTCCTGTCTCATTCAACAGACTCACTAAATAAAATCAGCAAGGTCAATGAGTCAACAGAATCACTTACTGATGAGGGAGTAGGTACAGACATGAATGAA
GGACAACTACTGGGAGACTTTGAGATTGAGTCCAAACAGCTGGAAGCAGAGTCTTGGAGTCGGATAATAGACAGCAAGTTTCTAAAACAGCAAAAGAAAG
ATGTGGTCAAACGGCAAGAAGTAATATATGAGTTGATGCAGACAGAGTTTCATCATGTCCGCACTCTCAAGATCATGAGTGGTGTGTACAGCCAGGGGAT
GATGGCGGATCTGCTTTTTGAGCAGCAGATGGTAGAAAAGCTGTTCCCCTGTTTGGATGAGCTGATCAGTATCCATAGCCAATTCTTCCAGAGGATTCTG
GAGCGGAAGAAGGAGTCTCTGGTGGATAAAAGTGAAAAGAACTTTCTCATCAAGAGGATAGGGGATGTGCTTGTAAATCAGTTTTCAGGTGAGAATGCAG
AACGTTTAAAGAAGACATATGGCAAGTTTTGTGGGCAACATAACCAGTCTGTAAACTACTTCAAAGACCTTTATGCCAAGGATAAGCGTTTTCAAGCCTT
TGTAAAGAAGAAGATGAGCAGTTCAGTTGTTAGAAGGCTTGGAATTCCAGAGTGCATATTGCTTGTAACTCAGCGGATTACCAAGTACCCAGTTTTATTC
CAAAGAATATTGCAGTGTACCAAAGACAATGAAGTGGAGCAGGAAGATCTAGCACAGTCCTTGAGCCTGGTGAAGGATGTGATTGGAGCTGTAGACAGCA
AAGTGGCAAGTTATGAAAAGAAAGTGCGTCTCAATGAGATTTATACAAAGACAGATAGCAAGTCAATCATGAGGATGAAGAGTGGTCAGATGTTTGCCAA
GGAAGATTTGAAACGGAAGAAGCTTGTACGTGATGGGAGTGTGTTTCTGAAGAATGCAGCAGGAAGGTTGAAAGAGGTTCAAGCAGTTCTTCTCACTGAC
ATTTTAGTTTTCCTTCAAGAAAAAGACCAGAAGTACATCTTTGCATCATTGGACCAGAAGTCAACAGTGATCTCTTTAAAGAAGCTGATTGTGAGAGAAG
TGGCACATGAGGAGAAAGGTTTATTCCTGATCAGCATGGGGATGACAGATCCAGAGATGGTAGAAGTCCATGCCAGCTCCAAAGAGGAACGAAACAGCTG
GATTCAGATCATTCAGGACACAATCAACACCCTGAACAGAGATGAAGATGAAGGAATTCCTAGTGAGAATGAGGAAGAAAAGAAAATGTTGGACACCAGA
GCCCGAGAATTAAAAGAACAACTTCACCAGAAGGACCAAAAAATCCTACTCTTGTTGGAAGAGAAGGAGATGATTTTCCGGGACATGGCTGAGTGCAGCA
CCCCTCTCCCAGAGGATTGCTCCCCAACACATAGCCCTAGAGTTCTCTTCCGCTCCAACACAGAAGAGGCTCTCAAAGGAGGACCTTTAATGAAAAGTGC
AATAAATGAGGTGGAGATCCTTCAGGGTTTGGTGAGTGGAAATCTGGGAGGCACACTTGGGCCGACTGTCAGCAGCCCCATTGAGCAAGATGTGGTCGGT
CCCGTTTCCCTGCCCCGGAGAGCAGAGACCTTTGGAGGATTTGACAGCCATCAGATGAATGCTTCAAAAGGAGGCGAGAAGGAAGAGGGAGATGATGGCC
AAGATCTTAGGAGAACGGAATCAGATAGTGGCCTAAAAAAGGGTGGAAATGCTAACCTGGTATTTATGCTTAAAAGAAACAGTGAGCAGGTTGTCCAGAG
CGTTGTTCATCTCTACGAGCTCCTCAGCGCTCTGCAGGGTGTGGTGCTGCAGCAGGACAGCTACATTGAGGACCAGAAACTGGTGCTGAGCGAGAGGGCG
CTCACTCGCAGCTTGTCCCGCCCGAGCTCCCTCATTGAGCAGGAGAAGCAGCGCAGCCTGGAGAAGCAGCGCCAGGACCTGGCCAACCTGCAGAAGCAGC
AGGCCCAGTACCTCGAGGAGAAGCGCAGGCGCGAGCGTGAGTGGGAAGCTCGTGAGAGGGAGCTGCGGGAGCGGGAGGCCCTCCTGGCCCAGCGCGAGGA
GGAGGTGCAGCAGGGGCAGCAGGACCTGGAAAAGGAGCGGGAGGAGCTCCAGCAGAAGAAGGGCACATACCAGTATGACCTGGAGCGACTGCGTGCTGCC
CAGAAACAGCTTGAGAGGGAACAGGAGCAGCTGCGCCGGGAGGCAGAGCGGCTCAGCCAGCGGCAGACAGAACGGGACCTGTGTCAGGTTTCCCATCCAC
ATACCAAGCTGATGAGGATCCCATCGTTCTTCCCCAGTCCTGAGGAGCCCCCCTCGCCATCTGCACCTTCCATAGCCAAATCAGGGTCATTGGACTCAGA
ACTTTCAGTGTCCCCAAAAAGGAACAGCATCTCTCGGACACACAAAGATAAGGGGCCTTTTCACATACTGAGTTCAACCAGCCAGACAAACAAAGGACCA
GAAGGGCAGAGCCAGGCCCCTGCGTCCACCTCTGCCTCTACCCGCCTGTTTGGGTTAACAAAGCCAAAGGAAAAGAAGGAGAAAAAAAAGAAGAACAAAA
CCAGCCGCTCTCAGCCCGGTGATGGTCCCGCGTCAGAAGTATCAGCAGAGGGTGAAGAGATCTTCTGCTGACCCTCTTCCTCTCTGCTGAGGCAGCTGCC
TCCTGATCCTGGCCAGCCCACCTCTCCTGCTGTCCCCGCGTGCACAAGTCTCTTACACTGGACGCCCACTGCTCCTCAGCGTCCAGTCCTCCTGGGCGGC
CCCAGGTCCTGGACAATAAGCAACAGATGATATTGAGTGTCGGGTGGGGAAGGAGGCCCAGACTCTGCTTCGGCCATGATTTGTGACTGCCCAGGACTCT
CAGGTTGGGCTGGCCCTACTCAGGATTACACTGAAAGTAATGGCCTCGTAAGTACAGGTGATGGTTTTGGACACGTCAGGAATTCCTAAAGGCTGAAAGA
GTGTATCCAAGTAAGGTCTGAACCTCCGAATGCCTTTTATTTGGGGGAACACAAAACCAAACAGCAGATGTTTTGGACTTGATCTGTGTACGTACATGGG
GACCTGTCTGCATATACACACGGGGAATGCCAGAAGAAGGCCCAGTCTGCACCAGGCGTCTGGTCAACTTAGCACAAGGGCAGTGCCTGGACGGACCCGG
AGCCCCCGCATATCAGCAGTTCACCCAGTACTCCTCAGAGACTGGTTTCCCTCTAAACCCATCCCGGGCACATACCACCCGTGTTTTGCATGTATTTCTC
ATTTCATTTTAGGGATGACAAACATTTGTGAAACCAGTGAGAGAAGGCTTGATGTGTATAAAAGACGTGATGTGCACCACCTCGATCTCGGTGTTTCAGG
CACTAAAGCAACAAAACAACCCATAGTATCTCATTCTGTCATCAGATCCAGAAGAAATATCCTGGTTTTCCAGCATGTTTACCCACATGTTTTGGCCATG
GATAAAGTGAAGAGGCCTACTCACCATTATCCCTGCAGCGTGACACCTTTTGATTGTCACTGACCACTCAGAAGGGGCCACGGCCTCCTGGCTGTGTTCC
TGAGCCCCCGTCGTGCCTCTCCCAGACAGCAGCTGTCTGGCCCTTGCTGGGTGAGGGCACACCACTGCCAGGGGTCAGCCTCGCACCCAGGCCAGGCAGA
AGCTGTGCTCTGAAGCTAGGACAGCTGGCTGAGAAGTGGGTTCAGGCGAAGGGTGAAGCCATGTGTAGCAGTTCCTGCCAGTGCAGATCTGGAGAGGAGC
TGGCCCGGAAGGCGTGGTTGTGAAAGCGCCCTTCTTATGTTAGGAGGCCTTGGCAAAATTGGATTTCTTCAAAAATACATGTAAAGGTCTGTTGTTGAAT
TGTACTCTGCCCCTGGAAGCAGATACAGATGGCTGCCTGCTGCTCGGCTTTGCTTTTGCTTTTCCCACCGTGTTTTCATCTTTGTTCACTTGAGGCTTTC
CCCAGCTGGTGTGTGCAGGACAGTTCATGGTAATGTTGCCCTCTGAGGCCCCGTACACCAGAAGGGAGGCCCTGGAAAATTTTGTGCTTCCAACGTGGCC
TTCAATTCTTGCTTTTTTGCCCCTCGGAAGCATGGGGCTTTTGAGCACACTTAAAAAAAGAAAAATCTGTAACTTGGTGCTTATTGATGAATTGCAAGCT
GGCCTTGCAGATGGAGATATTTATCTTTCAGTTTATTTGAAAGAGGTCTGGTTTAAAATTTGTAGCCTACATTTGTTTTATTTATTGTATTTGTGTGTTT
GTGTTTGTTTTTTTTTAAGGGTGAGCCAGGTCTAGCCCAACAGTCTAAACTATCCAGTCAATACCGAGTGAAGTGGCAGCCAGCACTGTTCACTCTGTGT
CTTTTGAAGTGCCTTGAAGGCCCAGATGAAATTTTAAAGGGAGGGGGTCCATGTCCTTCCCTCCCCCACCCCGCCTCATTCTTTAATCAAAGGATGTCTT
CTCCCTTGTTTGAGAATGAAGAAACTCGCCACCTCTGACCTACCTTTGCCTTTTTCTGTCATGGAGAATACTCACCCTTCAGAAACAGACCAAAGGCCAA
AACCTGCTGATTTTTCTATTGAAAATATGTCCCCTTGCAAAGACCCTAAACAAAAAGTTAAGTTTCTTTCTTTCACCTATTTGTACAACTCCAAGTTACA
GCTGAATCTGTCGTGACTTTCCTGAGATCTACCCGGGGCTTGGCTGTCTGTTCTGGGCACTGGCTCCGAGTTCCCCTCCTGGGATTTGCAGGAGGGCAGT
ACTGAACCTGCATTCTTCTCCTTGTAAATGTAGGCCGGGTGCCCCTGTTCTCCGGGTTTGGAACAATACGAGGTTGGTGCTGATGGGATTTACTTGCGTA
CGTGCTCTTCACAAAAACACCGTGGATGCTGAAGTTAGAGCACGTCGCCACAGAGCTTGACATCAATGTTAGAGGGTCTCTTACTCCCCGCCCAGCTGTG
ATGTTTCATCTGCTTTGGTTGTTTTGGTGGTCTTTTTTAAAAATAGAGATTTCACATCTGCCCAGACCCCACTCAAAACGATTTGGTCAGGTTCTGGTTG
GACAAGTTTAAAATCAAAGTAGTGCCCGGAATTCCCTCAAACCACCCAACTTCATCCAGGAATACAGTCTGCAGTGCAGCAACAGAACCGCTTACCAAGA
ACTGTGCTTACATACCTTTGTCATCTCTCTTCCCCCCTTGGAAGTTGTCCTCAGGGGGATTTGTTCCTGTCCTGGGGATTTACCTGGGATGGTGGCTGCC
TGTGCTTTTGCTCATGGCCTTGACAGTGCTCTAGTTGCTGGATCTAATGGCCTGTCTTGGTTTCTATCACATGAGAAGGGGTTGTTTTTTTGGGGTGACT
CGGACTGAATTCCCCATACTGTTTCCACGCCGGGACACCATGTTCTCCATCAAGCTAAAGAAATCACGTGCCTGAAACTGTGCTTAAGTTTTGGGGGAAA
GATGGAGTTCCTATCCAGAGCCCCCAGATTTCCAGAATCGAGTGAGCTTCCTGGAAGGAGACTGCGTCTTCTCTCAATTCCAGTCATCTCAGTCGTTGTC
GTTAGGTGACATGTGCACTTTAAATGCTCTCATCGGTTGGCTTCATTTTCAAGACAATCAAATGTATTGACTGTGTTTTCTTCTTAGAAAATGGAGAGGG
TTAAAAACATGCAAACTGCCACTTTCAACCTTTGCCAGTATTCCCTCTACCCCCGTGAGAGCTATCTGGGGGGAAGAATCCTTACCAAGGTTTTTTTGGA
AAGGTACGAATCTTAACTTTTTTCCCCTTCTGTGTCTCAGGGTAATACTATTCAGAGTCGCCCCTTTGCTCATTTTCTCCCGTATTTGTTACCTTCCTGA
GGCCTCAGTATTAGTCGTGAGCACAAAGTTTTGAGACCTTTGGCGTTGTTTCTTGATGTGGGAGGGGAGGTGTTAGTGCATGCAAGGGTTGAACTAGATA
GACCCTGCCTTAGTAGAGGGTGGGACTATAACCTTAGAGGCCAGAACTTGATCCAGAAGTTGCTGTCCACAGAAGTGCTTTCTATTTCATCATTTTTGTT
TCTAGGGCTCTTTTTCTGTAGCCAGGTCTTCCCAAGGATTTTAGTATTTGCATTGGAGTTGAGGTTTACTCTAATGATGGTGGCCCAGCTGTGCCCAGAG
GACAGCCAGGCAGGCCCTGGGAGGGAGTTTAGAAAGACAGTCCTGGTGAATGGGCTTCAAGTGGTCACAAAGAGGGTGGCTGTGAGGTGACCCCAGACAC
TGCAGAACGATGTGCACCCTCTGCGTTTTGGATGTCCTTGGAATGTGGGAGCCTAGAAATAACCCTGTGGATGGAATTGGGGCAGCGGCTGCTGGAGATC
TGTGTGCCTTGCCTTCCTTCAGCAGGACCGTCTAGGTGCGCAGCCACCTATGGATGCGTCCCAGCCAGCCCCGTCGCTCTCGTCCATCCTCAGAGACAAA
GAAGAGGGCAGGGAGTTTGGGCTTGGTTTTGAACTTTCCTTTCAATGTAGCAAAGCATTCCTAGTTAACCAGAGCCTTGGAATCTACTGCCTGCTGGCCA
GGCTTTAAAATGAAAAGTGTTTTAATGCTGCCATAAAAGGGAGGCGGGGGGGAGGAAGGGAAAATAAAGGCATCTTTCCAAGTACTCATCTAATTTAATT
GTCAAAAGATTGATAGGCCATGAATTACTTCTCCATCTCACTAAGGGTTAAAGGCGTGCAACCCCCCACTGGCTGTGTCCCCTGCCACCGAAGTGAGTGA
CCTGCCCTACAACCAGGTGGGACCACCTGTGCTGCAGTCCGGAGGGGCTTCTGCAGGAAGCACTCACCCCCCACACCTTCCCCGGCCTGAGCTTCCCCTA
CCTTTCGTCACCACCTGAGGGCATGAGCACAGGCCATGGGGCGTGCCTGGTGAGTCTGCCTGTGGTTCAGGCTTAGCCTGTGGTCTCCTGTGTGCTGCTG
CCCGCATGGGATGCGCAGGGGAGGCGTGGGGATCCGCAGGAGGGTGGTTGGGATACACCGGATACCTCTGCTCTCATTGCTTGTTTGCAAATGCTCTATG
GACATTTGTGTGCTAAATCCTATTAAATAAAAAAGACGGGTTAAAACCCAGATGCTGTATATTCATTTGTAATTATGTATAAAGTGAAGCAGTTTTAAAC
TGTAAAGATTTTTTTCAGTGTGTTTTCTCGAATTTTGCCACAACATACTGGCTTCGTATTTTATTTATCTTTCTTTCTAGTTACCAGCTTCAGACCCTTG
TAAAGTCTCCCTCAGCCCTTTCAAAAAATAATAAATTTCCTGTGAAGTTCTGG
  • AKAP13-F1 (forward primer)
  • AKAP13-R1 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

*VEVGEIEE*IISRCVVKCCSSGNHQYTEEGRF
LETGRRGDRGWAFPRAASASHPTLITLPPSSSGG
QPQPPLAT*VPRPGALLLVSCSEMGSSAVQSQL
AVLAPRVLTGGLAGVTAFPRAPPTLPSVFRRMR
GLELCAGPARSPSSRGEAPVLCRDCRAHCSPRSP
PL*PPPGERPPIVFLRGEGEELSQLGPRGSPGS
RTCPGS*NLIHSKLPYMVIVLLQCCLLKRTKLK
MM*CFTWYFWVPPSVTVQVLGRSVLIHWRPLLLV
MIVVKQ*RCSSVLPKRAFPCLWWLKKTFISSRM
KRMMQLNS*QPVLEISRL*TLPVFLTSQDPHLG
M*IPLIRSWCWHSGT*SCPRSGMYWGQIRVCMML
ARERH*CILLCGWDC*G*RGSCCRSQVAAELSV
STTRKGRRL*AWPWSEAITSCTSF*PRRMLENQ
TPGAVYPMKYRMETVL*GIIESWTSIH*PLSLIH
IMNTHFLETVALDQFLNL*TSNSN**KQTSSRW
TVLCP***QHRILPVPQRQMASFFPVHRSPRTL
SDFLLLKRLRALSAAQGALLHRLKVPVICQA*LR
RRIQTVPVGRKIKAWKEKGKRWSQHLLWTLELY
LIKTAAFRACLIVE*RARKAFRPVETEMKKLEQ
NLLECPQTRSP*AVEMLCFRETWSWSQAQPSIPL
EVNWEAFQQQMSVPQTLQGKWNMGS*TQMPLFG
RMCFREGKVQRKDLRTLILAQLEPLTCTSQVSL
WIKSVFQTVPLLPVPWMVTNLLSLHLHLVMKKPP
LKKQQKRKLHEVVRRVLMLQ*IRILW*FQLLQK
TRFQMD*NLILS*QQA*VRQCHPQI*PFLGWKK
M*CHTRTQKQIHLMLKAKRANPHPFVLQLETINF
VQTLHVNRTQ*LLVAIWLQNCVIT*LASPKAPQ
QGNPAHKIHPMPPTVKTHRLIQSPLTL*GIPRN
VRIFVLSKWWITKANEKM*N*INL*QICLRWFHI
HIQLSLKWRKNWCQTRQ*YQTVLSLWQTVQAVN
Q*PRMTHFLLSPPRKKREQQLLNYIQLQIIEMA
QMEIRMSLIRGH*KTGQ*ACPHPPLLQSFSTGWG
IPVSQDLVESMRVPPLQQSQKL*ISRGTLTLPC
KVWVRPLWL*IQF*LKKENFWWFQKALQLRNKI
RIKR*PVPLLRKMLSLQELCRKSREHHLLDKILN
NFMKNQSQLTVPRTKHFS*VIHRVHPLPFLRQK
LNITRKWPHKSHC*LKVGLPRAWCHQEQVWPQS
QGRKPWGQSTTAPLCCHVCCQMGLMGPMLLTAVS
LLLWMLE*RTLNPREKLVPVR*VEM*RWMLQGL
MLYKVWLSPEERIYHTTPKTS*FQTSC*AKRRM
PF*VCQWLYRTKL*LTHRELEPQR*YLLIGRKGS
WREQTTAVPWVTLRKPK*TMKHILSYCSLLPRS
SPQTWSSQPMMMGPQLV*GKSCEPRLQAGKGAL
PLYLAWSLPRTHLCLRGQT**RRLPAV*WMLSSN
KSRPLEHCLLRGRPVTCHCPALSWVLSLKD*RV
LLQKK*VLSHLGRAYQWAVLLRKPRGALQDVLL
EGRSQRRSFYLSRGLSQQQKCQT*KLKMKWILEQ
VQFLKKWL*GA*LLH*R*SKAQ*PRR*TEKTGV
Q*SHALMQHLFWLPSRAQNVRTSWMLDWAESVP
QNKVYLKENLGVILTSFTHPVMTWTASSSQSQRK
SIWPVISPDPVHPPMTRLHWTDILLMAVMCLSP
RF*SQTGQEIGKALMDSTAMGWELRVEKVRVSL
LTQATWRRRRWTVSLKCLQTALS*GAPCALFLPS
GGTAGGLGKMQPAMQK*TTGV*AGAPLVCSTLL
A*VLTLITE
VSV*KA*QEELVSETSHPHL*K*A
LQMPKSSDTHSVVRNGLTLWCHFQKRIWSQTREN
IGCLISRYVTDLSSRDLITVHQPFPLH*QNPSH
**QSAILDWTIHGPSTVPSTIPVLI*LRV*QKR
TIISCHIAPPRKILNGRVEQKSVVHSATSRIKCL
AARRAKKRKKKKIRLRRRRKILKTRRKIRRLST
GTLSVPFLLWVPSAVASV*SPSPTKMPILVQIA
VLLSTKAAEKV*PPVQRSK*SSPKGAFRHMTHHH
CPRSL*ETSPHSPRSVLGPQSSWWMKPLPPQYL
PIDDPSRVSRSPKVSPYRTLLELAMMRTCQTPG
NSCLIQQTH*IKSARSMSQQNHLLMRE*VQT*MK
DNYWETLRLSPNSWKQSLGVG**TASF*NSKRK
MWSNGKK*YMS*CRQSFIMSALSRS*VVCTARG
*WRICFLSSRW*KSCSPVWMS*SVSIANSSRGFW
SGRRSLWWIKVKRTFSSRG*GMCL*ISFQVRMQ
NV*RRHMASFVGNITSL*TTSKTFMPRISVFKP
L*RRR*AVQLLEGLEFQSAYCL*LSGLPSTQFYS
KEYCSVPKTMKWSRKI*HSP*AW*RM*LEL*TA
KWQVMKRKCVSMRFIQRQIASQS*G*RVVRCLP
RKI*NGRSLYVMGVCF*RMQQEG*KRFKQFFSLT
F*FSFKKKTRSTSLHHWTRSQQ*SL*RS*L*EK
WHMRRKVYS*SAWG*QIQRW*KSMPAPKRNETA
GFRSFRTQSTP*TEMKMKEFLVRMRKKRKCWTPE
PEN*KNNFTRRTKKSYSCWKRRR*FSGTWLSAA
PLSQRIAPQHIALEFSSAPTQKRLSKEDL**KV
Q*MRWRSFRVW*VEIWEAHLGRLSAAPLSKMWSV
PFPCPGEQRPLEDLTAIR*MLQKEARRKREMMA
KILGERNQIVA*KRVEMLTWYLCLKETVSRLSR
ALFISTSSSALCRVWCCSRTATLRTRNWC*ARGR
SLAACPARAPSLSRRSSAAWRSSARTWPTCRSS
RPSTSRRSAGASVSGKLVRGSCGSGRPSWPSAR
RRCSRGSRTWKRSGRSSSRRRAHTSMTWSDCVLP
RNSLRGNRSSCAGRQSGSASGRQNGTCVRFPIH
IPS**GSHRSSPVLRSPPRHLHLP*PNQGHWTQ
NFQCPQKGTASLGHTKIRGLFTY*VQPARQTKDQ
KGRARPLRPPLPLPACLG*QSQRKRRRKKRRTK
PAALSPVMVPRQKYQQRVKRSSADPLPLC*GSC
LLILASPPLLLSPRAQVSYTGRPLLLSVQSSWAA
PGPGQ*ATDDIECRVGKEAQTLLRP*FVTAQDS
QVGLALLRITLKVMAS*VQVMVLDTSGIPKG*K
SVSK*GLNLRMPFIWGNTKPNSRCFGLDLCTYMG
TCLHIHTGNARRRPSLHQASGQLSTRAVPGRTR
SPRISAVHPVLLRDWFPSKPIPGTYHPCFACIS
HFILGMTNICETSERRLDVYKRRDVHHLDLGVSG
TKATKQPIVSHSVIRSRRNILVFQHVYPHVLAM
DKVKRPTHHYPCSVTPFDCH*PLRRGHGLLAVF
LSPRRASPRQQLSGPCWVRAHHCQGSASHPGQAE
AVL*S*DSWLRSGFRRRVKPCVAVPASADLERS
WPGRRGCESALLMLGGLGKIGFLQKYM*RSVVE
LYSAPGSRYRWLPAARLCFCFSHRVFIFVHLRLS
PAGVCRTVHGNVAL*GPVHQKGGPGKFCASNVA
FNSCFFAPRKHGAFEHT*KKKNL*LGAY**IAS
WPCRWRYLSFSLFERGLV*NL*PTFVLFIVFVCL
CLFFFKGEPGLAQQSKLSSQYRVKWQPALFTLC
LLKCLEGPDEILKGGGPCPSLPHPASFFNQRMS
SPLFENEETRHL*PTFAFFCHGEYSPFRNRPKAK
TC*FFY*KYVPLQRP*TKS*VSFFHLFVQLQVT
AESVVTFLRSTRGLAVCSGHWLRVPLLGFAGGQ
Y*TCILLLVNVGRVPLFSGFGTIRGWC*WDLLAY
VLFTKTPWMLKLEHVATELDINVRGSLTPRPAV
MFHLLWLFWWSFLKIEISHLPRPHSKRFGQVLV
GQV*NQSSARNSLKPPNFIQEYSLQCSNRTAYQE
LCLHTFVISLPPLEVVLRGICSCPGDLPGMVAA
CAFAHGLDSALVAGSNGLSWFLSHEKGLFFWGD
SD*IPHTVSTPGHHVLHQAKEITCLKLCLSFGGK
MEFLSRAPRFPESSELPGRRLRLLSIPVISVVV
VR*HVHFKCSHRLASFSRQSNVLTVFSS*KMER
VKNMQTATFNLCQYSLYPRESYLGGRILTKVFLE
RYES*LFSPSVSQGNTIQSRPFAHFLPYLLPS*
GLSISREHKVLRPLALFLDVGGEVLVHARVELD
RPCLSRGWDYNLRGQNLIQKLLSTEVLSISSFLF
LGLFFCSQVFPRILVFALELRFTLMMVAQLCPE
DSQAGPGREFRKTVLVNGLQVVTKRVAVR*PQT
LQNDVHPLRFGCPWNVGA*K*PCGWNWGSGCWRS
VCLAFLQQDRLGAQPPMDASQPAPSLSSILRDK
EEGREFGLGFELSFQCSKAFLVNQSLGIYCLLA
RL*NEKCFNAAIKGRRGGGRENKGIFPSTHLI*L
SKD**AMNYFSISLRVKGVQPPTGCVPCHRSE*
PALQPGGTTCAAVRRGFCRKHSPPTPSPA*ASP
TFRHHLRA*AQAMGRAW*VCLWFRLSLWSPVCCC
PHGMRRGGVGIRRRVVGIHRIPLLSLLVCKCSM
DICVLNPIK*KRRVKTQMLYIHL*LCIK*SSFK
L*RFFSVCFLEFCHNILASYFIYLSF*LPASDPC
KVSLSPFKK**ISCEVL

Frame 1

ELKWGK*RSKSFHDVWLSAAAQVTTSTQRKGGF
WRQGGEETVGGHFPEQPLPATLL*SLCRRAAAA
VNLSLP*QPECPVQEPYYWSHAARWAVLPCNPSS
QFLLRVYSREDSQALPPSRVPRPPSRASFGACA
DWSCVQGQRGARAAAVKRLCSAETAVPIARLGR
RRFSRLRGSGRLLSFSAAKVKSCPSSARGGAPGA
ARVLGHET*STASSLIW*LCCYSAAC*RGQS*R
*CSVLLGIFGFHPPSLYKYSEGQF*YIGDHCSW
S*LL*NSEGAALCFQRGPSRVCGG*RRLSFRPG*
SV*CSSIPSNQCWKSAGFELYPFS*PVRTPIWG
CEFP**EVGAGIQAPEAAHGVECIGDRSEFA*C
WPARDIDAFCCAAGTAEVDVVPVAEARWPRSSQY
PQPGRGDACELGLGARLSQAAPASNRGECWRTR
LLEQFIL*NTVWRLFCEASSRVGHLYINL*V*F
TS*TPISWRRLHWTNF*TYEHPTATNENKPQADG
QSYALNDDSTGSFQCPRDRWPVSSLCTGAHGPS
ATFFF*RD*EHSVLPREPCCTD*KSL*FVKHS*
GGEYRPFL*EEK*RRGKKRGRGGASTYCGLWNCI
*SRQLPSELA*LWSKGHGRPFVLWKQK*RNWNK
IFWNAHRPGVPEQWRCCASERLGHGARHSPVFL
WR*TGRHFNNKCQYPRHCRGNGTWAHEPRCHCLE
ECASGRGKYKGKI*EL*YWHSWSL*RARHK*AC
G*NQCSKLCPCCQFPGW*QTC*VFTCI***RNL
H*KNSRNGNFTKS*GEC*CSSRSEFCGDSSCCKR
QDFRWIRTLYSLSSRHR*GNVTLRFSPSWAGRR
CNATPELRNKFISCSKPKGQILTHLFYNWRR*T
LCRLCMSTEHSDF*WRFGCKTV**HS*RVRKHHS
KATQLTRSTRCLPL*RPTGSYSHL*PCKGYPGT
CGFLSFQSGG*QRPTKRCETR*TFNKYA*GGFT
STSSCP*NGERTGARPGSNIRQYFLSGKQSRQ*I
SNQG*RTFFCPLPERKGNSNS*TTYSYRL*RWP
RWKFE*A*YAATRRQGSRPVHILHCCRASARDG
EYQSHRTWWRA*GSRPSSNPRSSEYQGEH*LFPA
KCG*GHFGFRFSFD*RRKTSGGFRKLCSSGTR*
G*SGDLFLY*GKCSLFRNFAGRAENTTSWTRYS
TIS*KINLS*LCQGQSTSAK*FTGCILCLS*GRN
*T*QGSGPTSLTADSRWGCPEPGATRSKSGHRV
KAGSLGGRAQQLRSVAMSVARWV*WVRCS*LQS
AFSSGCWSEEHSIPGKN*CL*GEWRCDGGCYRG*
CSTRYG*AQKREYITQHPRHPDSKRLVEPREEC
RSRFASGSTGQSCD*PTGSWNPRDDTS*LGERE
AGGSRPQLYHG*R*GSPNRR*STSCPTAACCQGA
PHRHGALSP**WGPSWCEGSHASPAFRQGKEHS
LSTLHGLCPGRTSA*GGRLDRGGCQPYSGCCHR
TSQGRWSTAY*GGGLSHVTVQP*VGSSH*RTREC
FYRKSEYFPTWGEPTNGQYS*GSHGEPCRMFCW
KGGAREDHFTCPGA*ASSRNARRES*R*SGF*S
KFNF*RSGCREHSCYTEDEARPNDPGDKPRKLVY
NRAMP*CSISSGFQAEPRM*ELPGCWTGQRVYL
KTRCT*KRIWE*F*PLSLTQ**HGQHHLPKARG
RAFGL*YHRIQFIHR*HGFTGPTFFSWQ*CVSLP
DFKAKQVKRSAKP*WILQPWDGS*GSRK*E*AC
*PRRRGGGGDGQYH*SACKLLCPKELHALSFSL
PEAQLGAWEKCSQRCRNEPPEYELVPLWCAVLCW
PEC*L*LQK
FQSRRLDRRSWCRKQAILISRSKL
CKCRRAQTPIQW*GTG*LFGVTFRRGSGVRPER
T
*DV*SADMSQI*AAGI*LLYISHFLSIDKIHLI
NDNQPSWIGQFTALPQYLPQYQC*SD*EYNRRE
L*FPAT*PLQERF*MEEWNKSQSYIQLHQE*NV
*QQEEQRKGKRKR*D*GEGERF*RQGER*EDCQR
AHFQFHSCCGSHQL*PVYEALHQQRCLYLCKLQ
CFCPQRLPRKSSLLCKGQNEAAQREPSGT*HII
TAHGHYEKQALTAQGASSVRSPPGG*NRYHPNIC
Q*TIPAECLALQKCLHTEHYWSWQ**EHVKHLE
IPVSFNRLTK*NQQGQ*VNRITY**GSRYRHE*
RTTTGRL*D*VQTAGSRVLESDNRQQVSKTAKER
CGQTARSNI*VDADRVSSCPHSQDHEWCVQPGD
DGGSAF*AADGRKAVPLFG*ADQYP*PILPEDS
GAEEGVSGG*K*KELSHQEDRGCACKSVFR*ECR
TFKEDIWQVLWAT*PVCKLLQRPLCQG*AFSSL
CKEEDEQFSC*KAWNSRVHIACNSADYQVPSFI
PKNIAVYQRQ*SGAGRSSTVLEPGEGCDWSCRQQ
SGKL*KESASQ*DLYKDR*QVNHEDEEWSDVCQ
GRFETEEACT*WECVSEECSRKVERGSSSSSH*
HFSFPSRKRPEVHLCIIGPEVNSDLFKEADCERS
GT*GERFIPDQHGDDRSRDGRSPCQLQRGTKQL
DSDHSGHNQHPEQR*R*RNS**E*GRKENVGHQ
SPRIKRTTSPEGPKNPTLVGREGDDFPGHG*VQH
PSPRGLLPNT*P*SSLPLQHRRGSQRRTFNEKC
NK*GGDPSGFGEWKSGRHTWADCQQPH*ARCGR
SRFPAPESRDLWRI*QPSDECFKRRREGRGR*WP
RS*ENGIR*WPKKGWKC*PGIYA*KKQ*AGCPE
RCSSLRAPQRSAGCGAAAGQLH*GPETGAEREG
AHSQLVPPELPH*AGEAAQPGEAAPGPGQPAEAA
GPVPRGEAQARA*VGSS*EGAAGAGGPPGPARG
GGAAGAAGPGKGAGGAPAEEGHIPV*PGATACC
PETA*EGTGAAAPGGRAAQPAADRTGPVSGFPST
YQADEDPIVLPQS*GAPLAICTFHSQIRVIGLR
TFSVPKKEQHLSDTQR*GAFSHTEFNQPDKQRT
RRAEPGPCVHLCLYPPVWVNKAKGKEGEKKEEQN
QPLSAR*WSRVRSISRG*RDLLLTLFLSAEAAA
S*SWPAHLSCCPRVHKSLTLDAHCSSASSPPGR
PQVLDNKQQMILSVGWGRRPRLCFGHDL*LPRTL
RLGWPYSGLH*K*WPRKYR*WFWTRQEFLKAER
VYPSKV*TSECLLFGGTQNQTADVLDLICVRTW
GPVCIYTRGMPEEGPVCTRRLVNLAQGQCLDGPG
APAYQQFTQYSSETGFPLNPSRAHTTRVLHVFL
ISF*G*QTFVKPVREGLMCIKDVMCTTSISVFQ
ALKQQNNP*YLILSSDPEEISWFSSMFTHMFWPW
IK*RGLLTIIPAA*HLLIVTDHSEGATASWLCS
*APVVPLPDSSCLALAG*GHTTARGQPRTQARQ
KLCSEARTAG*EVGSGEG*SHV*QFLPVQIWRGA
GPEGVVVKAPFLC*EALAKLDFFKNTCKGLLLN
CTLPLEADTDGCLLLGFAFAFPTVFSSLFT*GF
PQLVCAGQFMVMLPSEAPYTRREALENFVLPTWP
SILAFLPLGSMGLLSTLKKRKICNLVLIDELQA
GLADGDIYLSVYLKEVWFKICSLHLFYLLYLCV
CVCFFLRVSQV*PNSLNYPVNTE*SGSQHCSLCV
F*SALKAQMKF*REGVHVLPSPTPPHSLIKGCL
LPCLRMKKLATSDLPLPFSVMENTHPSETDQRP
KPADFSIENMSPCKDPKQKVKFLSFTYLYNSKLQ
LNLS*LS*DLPGAWLSVLGTGSEFPSWDLQEGS
TEPAFFSL*M*AGCPCSPGLEQYEVGADGIYLR
TCSSQKHRGC*S*STSPQSLTSMLEGLLLPAQL*
CFICFGCFGGLF*K*RFHICPDPTQNDLVRFWL
DKFKIKVVPGIPSNHPTSSRNTVCSAATEPLTK
NCAYIPLSSLFPPWKLSSGGFVPVLGIYLGWWLP
VLLLMALTVL*LLDLMACLGFYHMRRGCFFGVT
RTEFPILFPRRDTMFSIKLKKSRA*NCA*VLGE
RWSSYPEPPDFQNRVSFLEGDCVFSQFQSSQSLS
LGDMCTLNALIGWLHFQDNQMY*LCFLLRKWRG
LKTCKLPLSTFASIPSTPVRAIWGEESLPRFFW
KGTNLNFFPLLCLRVILFRVAPLLIFSRICYLPE
ASVLVVSTKF*DLWRCFLMWEGRC*CMQGLN*I
DPALVEGGTITLEART*SRSCCPQKCFLFHHFC
F*GSFSVARSSQGF*YLHWS*GLL**WWPSCAQR
TARQALGGSLERQSW*MGFKWSQRGWL*GDPRH
CRTMCTLCVLDVLGMWEPRNNPVDGIGAAAAGD
LCALPSFSRTV*VRSHLWMRPSQPRRSRPSSETK
KRAGSLGLVLNFPFNVAKHS*LTRALESTACWP
GFKMKSVLMLP*KGGGGEEGKIKASFQVLI*FN
CQKIDRP*ITSPSH*GLKACNPPLAVSPATEVSD
LPYNQVGPPVLQSGGASAGSTHPPHLPRPELPL
PFVTT*GHEHRPWGVPGESACGSGLACGLLCAA
ARMGCAGEAWGSAGGWLGYTGYLCSHCLFANALW
TFVC*ILLNKKDGLKPRCCIFICNYV*SEAVLN
CKDFFQCVFSNFATTYWLRILFIFLSSYQLQTL
VKSPSALSKNNKFPVKFW

Frame 2

S*SGGNRGVNHFTMCG*VLQLR*PPVHRGRAVS
GDRAERRPWVGISQSSLCQPPYFDHFAAEQQRR
STSASLSNLSAPSRSLTIGLMQRDGQFCRAIPA
RSSCSACTHGRTRRRYRLPACPAHPPERLSAHAR
TGAVCRASAEPEQPR*SACALPRLPCPLLASVA
AALAASGGAAAYCLSPRRR*RVVPARPAGEPRE
PHVSWVMKLNPQQAPLYGDCVVTVLLAEEDKAED
DVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPG
HDCCETVKVQLCASKEGLPVFVVAEEDFHFVQD
EAYDAAQFLATSAGNQQALNFTRFLDQSGPPSGD
VNSLDKKLVLAFRHLKLPTEWNVLGTDQSLHDA
GPRETLMHFAVRLGLLRLTWFLLQKPGGRGALS
IHNQEGATPVSLALERGYHKLHQLLTEENAGEPD
SWSSLSYEIPYGDCSVRHHRELDIYTLTSESDS
HHEHPFPGDGCTGPIFKLMNIQQQLMKTNLKQM
DSLMPLMMTAQDPSSAPETDGQFLPCAPEPTDPQ
RLSSSEETESTQCCPGSPVAQTESPCDLSSIVE
EENTDRSCRKKNKGVERKGEEVEPAPIVDSGTV
SDQDSCLQSLPDCGVKGTEGLSSCGNRNEETGTK
SSGMPTDQESLSSGDAVLQRDLVMEPGTAQYSS
GGELGGISTTNVSTPDTAGEMEHGLMNPDATVW
KNVLQGGESTKERFENSNIGTAGASDVHVTSKPV
DKISVPNCAPAASSLDGNKPAESSLAFSNEETS
TEKTAETETSRSREESADAPVDQNSVVIPAAAK
DKISDGLEPYTLLAAGIGEAMSPSDLALLGLEED
VMPHQNSETNSSHAQSQKGKSSPICSTTGDDKL
CADSACQQNTVTSSGDLVAKLCDNIVSESESTT
ARQPSSQDPPDASHCEDPQAHTVTSDPVRDTQER
ADFCPFKVVDNKGQRKDVKLDKPLTNMLEVVSH
PHPVVPKMEKELVPDQAVISDSTFSLANSPGSE
SVTKDDALSFVPSQKEKGTATPELHTATDYRDGP
DGNSNEPDTRPLEDRAVGLSTSSTAAELQHGMG
NTSLTGLGGEHEGPAPPAIPEALNIKGNTDSSL
QSVGKATLALDSVLTEEGKLLVVSESSAAQEQDK
DKAVTCSSIKENALSSGTLQEEQRTPPPGQDTQ
QFHEKSISADCAKDKALQLSNSPGASSAFLKAE
TEHNKEVAPQVSLLTQGGAAQSLVPPGASLATES
RQEALGAEHNSSALLPCLLPDGSDGSDALNCSQ
PSPLDVGVKNTQSQGKTSACEVSGDVTVDVTGV
NALQGMAEPRRENISHNTQDILIPNVLLSQEKNA
VLGLPVALQDKAVTDPQGVGTPEMIPLDWEKGK
LEGADHSCTMGDAEEAQIDDEAHPVLLQPVAKE
LPTDMELSAHDDGAPAGVREVMRAPPSGRERSTP
SLPCMVSAQDAPLPKGADLIEEAASRIVDAVIE
QVKAAGALLTEGEACHMSLSSPELGPLTKGLES
AFTEKVSTFPPGESLPMGSTPEEATGSLAGCFAG
REEPEKIILPVQGPEPAAEMPDVKAEDEVDFRA
SSISEEVAVGSIAATLKMKQGPMTQAINRENWC
TIEPCPDAASLLASKQSPECENFLDVGLGRECTS
KQGVLKRESGSDSDLFHSPSDDMDSIIFPKPEE
EHLACDITGSSSSTDDTASLDRHSSHGSDVSLS
QILKPNRSRDRQSLDGFYSHGMGAEGRESESEPA
DPGDVEEEEMDSITEVPANCSVLRSSMRSLSPF
RRHSWGPGKNAASDAEMNHRSMSWCPSGVQYSA
GLSADFNYRS
FSLEGLTGGAGVGNKPSSSLEVSS
ANAEELRHPFSGEERVDSLVSLSEEDLESDQRE
HRMFDQQICHRSKQQGFNYCTSAISSPLTKSIS
LMTISHPGLDNSRPFHSTFHNTSANLTESITEEN
YNFLPHSPSKKDSEWKSGTKVSRTFSYIKNKMS
SSKKSKEKEKEKDKIKEKEKDSKDKEKDKKTVN
GHTFSSIPVVGPISCSQCMKPFTNKDAYTCANCS
AFVHKGCRESLASCAKVKMKQPKGSLQAHDTSS
LPTVIMRNKPSQPKERPRSAVLLVDETATTPIF
ANRRSQQSVSLSKSVSIQNITGVGNDENMSNTWK
FLSHSTDSLNKISKVNESTESLTDEGVGTDMNE
GQLLGDFEIESKQLEAESWSRIIDSKFLKQQKK
DVVKRQEVIYELMQTEFHHVRTLKIMSGVYSQGM
MADLLFEQQMVEKLFPCLDELISIHSQFFQRIL
ERKKESLVDKSEKNFLIKRIGDVLVNQFSGENA
ERLKKTYGKFCGQHNQSVNYFKDLYAKDKRFQAF
VKKKMSSSVVRRLGIPECILLVTQRITKYPVLF
QRILQCTKDNEVEQEDLAQSLSLVKDVIGAVDS
KVASYEKKVRLNEIYTKTDSKSIMRMKSGQMFAK
EDLKRKKLVRDGSVFLKNAAGRLKEVQAVLLTD
ILVFLQEKDQKYIFASLDQKSTVISLKKLIVRE
VAHEEKGLFLISMGMTDPEMVEVHASSKEERNSW
IQIIQDTINTLNRDEDEGIPSENEEEKKMLDTR
ARELKEQLHQKDQKILLLLEEKEMIFRDMAECS
TPLPEDCSPTHSPRVLFRSNTEEALKGGPLMKSA
INEVEILQGLVSGNLGGTLGPTVSSPIEQDVVG
PVSLPRRAETFGGFDSHQMNASKGGEKEEGDDG
QDLRRTESDSGLKKGGNANLVFMLKRNSEQVVQS
VVHLYELLSALQGVVLQQDSYIEDQKLVLSERA
LTRSLSRPSSLIEQEKQRSLEKQRQDLANLQKQ
QAQYLEEKRRREREWEARERELREREALLAQREE
EVQQGQQDLEKEREELQQKKGTYQYDLERLRAA
QKQLEREQEQLRREAERLSQRQTERDLCQVSHP
HTKLMRIPSFFPSPEEPPSPSAPSIAKSGSLDSE
LSVSPKRNSISRTHKDKGPFHILSSTSQTNKGP
EGQSQAPASTSASTRLFGLTKPKEKKEKKKKNK
TSRSQPGDGPASEVSAEGEEIFC*PSSSLLRQLP
PDPGQPTSPAVPACTSLLHWTPTAPQRPVLLGG
PRSWTISNR*Y*VSGGEGGPDSASAMICDCPGL
SGWAGPTQDYTESNGLVSTGDGFGHVRNS*RLKE
CIQVRSEPPNAFYLGEHKTKQQMFWT*SVYVHG
DLSAYTHGECQKKAQSAPGVWST*HKGSAWTDP
EPPHISSSPSTPQRLVSL*THPGHIPPVFCMYFS
FHFRDDKHL*NQ*EKA*CV*KT*CAPPRSRCFR
H*SNKTTHSISFCHQIQKKYPGFPACLPTCFGH
G*SEEAYSPLSLQRDTF*LSLTTQKGPRPPGCVP
EPPSCLSQTAAVWPLLGEGTPLPGVSLAPRPGR
SCALKLGQLAEKWVQAKGEAMCSSSCQCRSGEE
LARKAWL*KRPSYVRRPWQNWISSKIHVKVCC*I
VLCPWKQIQMAACCSALLLLFPPCFHLCSLEAF
PSWCVQDSSW*CCPLRPRTPEGRPWKILCFQRG
LQFLLFCPSEAWGF*AHLKKEKSVTWCLLMNCKL
ALQMEIFIFQFI*KRSGLKFVAYICFIYCICVF
VFVFF*G*ARSSPTV*TIQSIPSEVAASTVHSV
SFEVP*RPR*NFKGRGSMSFPPPPRLIL*SKDVF
SLV*E*RNSPPLTYLCLFLSWRILTLQKQTKGQ
NLLIFLLKICPLAKTLNKKLSFFLSPICTTPSY
S*ICRDFPEIYPGLGCLFWALAPSSPPGICRRAV
LNLHSSPCKCRPGAPVLRVWNNTRLVLMGFTCV
RALHKNTVDAEVRARRHRA*HQC*RVSYSPPSC
DVSSALVVLVVFFKNRDFTSAQTPLKTIWSGSGW
TSLKSK*CPEFPQTTQLHPGIQSAVQQQNRLPR
TVLTYLCHLSSPLGSCPQGDLFLSWGFTWDGGC
LCFCSWP*QCSSCWI*WPVLVSIT*EGVVFLG*L
GLNSPYCFHAGTPCSPSS*RNHVPETVLKFWGK
DGVPIQSPQISRIE*ASWKETASSLNSSHLSRC
R*VTCAL*MLSSVGFIFKTIKCIDCVFFLENGEG
*KHANCHFQPLPVFPLPP*ELSGGKNPYQGFFG
KVRILTFFPFCVSG*YYSESPLCSFSPVFVTFL
RPQY*S*AQSFETFGVVS*CGRGGVSACKG*TR*
TLP**RVGL*P*RPELDPEVAVHRSAFYFIIFV
SRALFL*PGLPKDFSICIGVEVYSNDGGPAVPR
GQPGRPWEGV*KDSPGEWASSGHKEGGCEVTPDT
AERCAPSAFWMSLECGSLEITLWMELGQRLLEI
CVPCLPSAGPSRCAATYGCVPASPVALVHPQRQ
RRGQGVWAWF*TFLSM*QSIPS*PEPWNLLPAGQ
ALK*KVF*CCHKREAGGRKGK*RHLSKYSSNLI
VKRLIGHELLLHLTKG*RRATPHWLCPLPPK*V
TCPTTRWDHLCCSPEGLLQEALTPHTFPGLSFPY
LSSPPEGMSTGHGACLVSLPVVQA*PVVSCVLL
PAWDAQGRRGDPQEGGWDTPDTSALIACLQMLY
GHLCAKSY*IKKTG*NPDAVYSFVIMYKVKQF*T
VKIFFSVFSRILPQHTGFVFYLSFFLVTSFRPL
*SLPQPFQKIINFL*SS

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