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PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa
PRPF8 knockdown in human cell lines Tanackovic et al.
Transcript map
: BCL2L12 siPRPF8 global_2|MCF7 (2007-07-13 96hrs)
- BCL2L12-3 / BCL2L12-4 (CM014100 A14) : Curve | Curve set
- BCL2L12-3 / BCL2L12-4 (CM014100 A14) : Curve | Curve set
- BCL2L12-3 / BCL2L12-4 (CM014100 B13) : Curve | Curve set
- BCL2L12-3 / BCL2L12-4 (CM014100 B13) : Curve | Curve set
- BCL2L12-3 / BCL2L12-4 (CM014100 B14) : Curve | Curve set
- BCL2L12-3 / BCL2L12-4 (CM014100 B14) : Curve | Curve set
Exon
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Exon
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Exon
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Exon
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Length: 87
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Exon
Length: 92
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Length: 92
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Exon
Length: 273
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Length: 273
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Exon
Length: 218
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Length: 218
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Intron
Length: 617
Transcript: ENST00000246784
Length: 617
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Intron
Length: 219
Transcript: ENST00000246784
Length: 219
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Intron
Length: 1689
Transcript: ENST00000246784
Length: 1689
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Intron
Length: 86
Transcript: ENST00000246784
Length: 86
Transcript: ENST00000246784
Intron
Length: 1100
Transcript: ENST00000246784
Length: 1100
Transcript: ENST00000246784
Intron
Length: 3209
Transcript: ENST00000246784
Length: 3209
Transcript: ENST00000246784
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Exon
Length: 926
Transcript: ENST00000246784
Length: 926
Transcript: ENST00000246784
Exon
Length: 115
Transcript: ENST00000246784
Length: 115
Transcript: ENST00000246784
Exon
Length: 143
Transcript: ENST00000246784
Length: 143
Transcript: ENST00000246784
Exon
Length: 87
Transcript: ENST00000246784
Length: 87
Transcript: ENST00000246784
Exon
Length: 92
Transcript: ENST00000246784
Length: 92
Transcript: ENST00000246784
Exon
Length: 273
Transcript: ENST00000246784
Length: 273
Transcript: ENST00000246784
Exon
Length: 218
Transcript: ENST00000246784
Length: 218
Transcript: ENST00000246784
Intron
Length: 617
Transcript: ENST00000246784
Length: 617
Transcript: ENST00000246784
Intron
Length: 219
Transcript: ENST00000246784
Length: 219
Transcript: ENST00000246784
Intron
Length: 1689
Transcript: ENST00000246784
Length: 1689
Transcript: ENST00000246784
Intron
Length: 86
Transcript: ENST00000246784
Length: 86
Transcript: ENST00000246784
Intron
Length: 1100
Transcript: ENST00000246784
Length: 1100
Transcript: ENST00000246784
Intron
Length: 3209
Transcript: ENST00000246784
Length: 3209
Transcript: ENST00000246784
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Expected peak: 330
6.5M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Expected peak: 330
8.7M
BCL2L12-3
BCL2L12-4
Exon
Length: 244
Transcript: ENST00000246785
Length: 244
Transcript: ENST00000246785
Exon
Length: 115
Transcript: ENST00000246785
Length: 115
Transcript: ENST00000246785
Exon
Length: 87
Transcript: ENST00000246785
Length: 87
Transcript: ENST00000246785
Exon
Length: 85
Transcript: ENST00000246785
Length: 85
Transcript: ENST00000246785
Intron
Length: 617
Transcript: ENST00000246785
Length: 617
Transcript: ENST00000246785
Intron
Length: 2051
Transcript: ENST00000246785
Length: 2051
Transcript: ENST00000246785
Intron
Length: 86
Transcript: ENST00000246785
Length: 86
Transcript: ENST00000246785
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Exon
Length: 244
Transcript: ENST00000246785
Length: 244
Transcript: ENST00000246785
Exon
Length: 115
Transcript: ENST00000246785
Length: 115
Transcript: ENST00000246785
Exon
Length: 87
Transcript: ENST00000246785
Length: 87
Transcript: ENST00000246785
Exon
Length: 85
Transcript: ENST00000246785
Length: 85
Transcript: ENST00000246785
Intron
Length: 617
Transcript: ENST00000246785
Length: 617
Transcript: ENST00000246785
Intron
Length: 2051
Transcript: ENST00000246785
Length: 2051
Transcript: ENST00000246785
Intron
Length: 86
Transcript: ENST00000246785
Length: 86
Transcript: ENST00000246785
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Expected peak: 187
14.4M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Expected peak: 187
6.2M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Reaction
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
Expected peak: 187
13.6M
BCL2L12-3
BCL2L12-4
BCL2L12-3
TCCTAGCTGCCTTCCTTAG
TCCTAGCTGCCTTCCTTAG
BCL2L12-4
GTATGGCTTCCTTCTCTGTC
GTATGGCTTCCTTCTCTGTC