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Sequences

Sequence ADAM9.eAug05

AAGCCAAGGCTGCCCCCAAAGATTGTTTCATTGAAGTGAATTCTAAAGGTGACAGATTTGGCAATTGTGGTTTCTCTGGCAATGAATACAAGAAGTGTGC
CACTGGGAATGCTTTGTGTGGAAAGCTTCAGTGTGAGAATGTACAAGAGATACCTGTATTTGGAATTGTGCCTGCTATTATTCAAACGCCTAGTCGAGGC
ACCAAATGTTGGGGTGTGGATTTCCAGCTAGGATCAGATGTTCCAGATCCTGGGATGGTTAACGAAGGCACAAAATGTGGTGCTGGAAAGATCTGTAGAA
ACTTCCAGTGTGTAGATGCTTCTGTTCTGAATTATGACTGTGATGTTCAGAAAAAGTGTCATGGACATGGGGTAGGTAATGTTTTCTTTTGAAATGAATA
CTGCATTGAGGGACGGACTTCTGGTCTTCTTCTTCCTAATTGTTCCCCTTATTGTCTGTGCTATTTTTATCTTCATCAAGAGGGATCAACTGTGGAGAAG
CTACTTCAGAAAGAAGAGATCACAAACATATGAGTCAGATGGCAAAAATCAAGCAAACCCTTCTAGACAGCCGGGGAGTGTTCCTCGACATGTTTCTCCA
GTGACACCTCCCAGAGAAGTTCCTATATATGCAAACAGATTTGCAGTACCAACCTATGCAGCCAAGCAACCTCAGCAGTTCCCATCA
  • ADAM9.F3 (forward primer)
  • ADAM9.R3 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

KPRLPPKIVSLK*ILKVTDLAIVVSLAMNTRSV
PLGMLCVESFSVRMYKRYLYLELCLLLFKRLVEA
PNVGVWISS*DQMFQILGWLTKAQNVVLERSVE
TSSV*MLLF*IMTVMFRKSVMDMG*VMFSFEMN
TALRDGLLVFFFLIVPLIVCAIFIFIKRDQLWRS
YFRKKRSQTYESDGKNQANPSRQPGSVPRHVSP
VTPPREVPIYANRFAVPTYAAKQPQQFPS

Frame 1

SQGCPQRLFH*SEF*R*QIWQLWFLWQ*IQEVC
HWECFVWKASV*ECTRDTCIWNCACYYSNA*SR
HQMLGCGFPARIRCSRSWDG*RRHKMWCWKDL*K
LPVCRCFCSEL*L*CSEKVSWTWGR*CFLLK*I
LH*GTDFWSSSS*LFPLLSVLFLSSSRGINCGE
ATSERRDHKHMSQMAKIKQTLLDSRGVFLDMFLQ
*HLPEKFLYMQTDLQYQPMQPSNLSSSH

Frame 2

AKAAPKDCFIEVNSKGDRFGNCGFSGNEYKKCA
TGNALCGKLQCENVQEIPVFGIVPAIIQTPSRG
TKCWGVDFQLGSDVPDPGMVNEGTKCGAGKICR
NFQCVDASVLNYDCDVQKKCHGHGVGNVFF*NEY
CIEGRTSGLLLPNCSPYCLCYFYLHQEGSTVEK
LLQKEEITNI*VRWQKSSKPF*TAGECSSTCFS
SDTSQRSSYICKQICSTNLCSQATSAVPI

Sequence ADAM9.dAug05

TTCCTTCCAGGAGGTACTTTATGCCGAGGAAAAACCAGTGAGTGTGATGTTCCAGAGTACTGCAATGGTTCTTCTCAGTTCTGTCAGCCAGATGTTTTTA
TTCAGAATGGATATCCTTGCCAGAATAACAAAGCCTATTGCTACAACGGCATGTGCCAGTATTATGATGCTCAATGTCAAGTCATCTTTGGCTCAAAAGC
CAAGGCTGCCCCCAAAGATTGTTTCATTGAAGTGAATTCTAAAGGTGACAGATTTGGCAATTGTGGTTTCTCTGGCAATGAATACAAGAAGTGTGCCACT
GGGAATGCTTTGTGTGGAAAGCTTCAGTGTGAGAATGTACAAGAGATACCTGTATTTGGAATTGTGCCTGCTATTATTCAAACGCCTAGTCGAGGCACCA
AATGTTGGGGTGTGGATTTCCAGCTAGGATCAGATGTTCCAGATCCTGGGATGGTTAACGAAGGCACAAAATGTGGTGCTGGAAAGATCTGTAGAAACTT
CCAGTGTGTAGATGCTTCTGTTCTGAATTATGACTGTGATGTTCAGAAAAAGTGTCATGGACATGGGGTATGTAATAGCAATAAGAATTGTCACTGTGAA
AATGGCTGGGCTCCCCCAAATTGTGAGACTAAAGGATACGGAGGAAGTGTGGACAGTGGACCTACATACAATGGCAAAAATGAATACTGCATTGAGGGAC
GGACTTCTGGTCTTCTTCTTCCTAATTGTTCCCCTTATTGTCTGTGCTATTTTTATCTTCATCAAGAGGGATCAACTGTGGAGAAGCTACTTCAGAAAGA
AGAGATCACAAACATATGAGTCAGATGGCAAAAATCAAGCAAACCCTTCTAGACAGCCGGGGAGTGTTCCTCGACATGTTTCTCCAGTGACACCTCCCAG
AGAAGTTCCTATATATGCAAACAGATTTGCAGTACCAACCTATGCAGCCAAGCAACCTCAGCAGTTCCCATCAAGGCCACCTCCACCACAACCGAAAGTA
TCATCTCAGGGAAACTTAATTCCTGCCCGTCCTGCTCCTGCACCTCCTTTATATAGTTCCCTCACTTGATTTTTTTAACCTTCTTTTTGCAAATGTCTTC
AGGGAACTGAGCTAATACTTTTTTTTTTTCTTGATGTTTTCTTGAAAAGCCTTTCTGTTGCAACTATGAATGAAAACAAAACACCACAAAACAGACTTCA
CTAACACAGAAAAACAGAAACTGAGTGTGAGAGTTGTGAAATACAAGGAAATGCAGTAAAGCCAGGGAATTTACAATAACATTTCCGTTTCCATCATTGA
ATAAGTCTTATTCAGTCATCGGTGAGGTTAATGCACTAATCATGGATTTTTTGAACATGTTATTGCAGTGATTCTCAAATTAACTGTATTGGTGTAAGAG
TTTTGTCATTAAGTGTTTAAGTGTTATTCTGAATTTTCTACCTTAGTTATCATTAATGTAGTTCCTCATTGAACATGTGATAATCTAATACCTGTGAAAA
CTGACTAATCAGCTGCCAATAATATCTAATATTTTTCATCATGCACGAATTAATAATCATCATACTCTAGAATCTTGTCTGTCACTCACTACATGAATAA
GCAAATATTGTCTTCAAAAGAATGCACAAGAACCACAATTAAGATGTCATATTATTTTGAAAGTACAAAATATACTAAAAGAGTGTGTGTGTATTCACGC
AGTTACTCGCTTCCATTTTTATGACCTTTCAACTATAGGTAATAACTCTTAGAGAAATTAATTTAATATTAGAATTTCTATTATGAATCATGTGAAAGCA
TGACATTCGTTCACAATAGCACTATTTTAAATAAATTATAAGCTTTAAGGTACGAAGTATTTAATAGATCTAATCAAATATGTTGATTCATGGCTATAAT
AAAGCAGGAGCAATTATAAAATCTTCAATCAATTGAACTTTTACAAAACCACTTGAGAATTTCATGAGCACTTTAAAATCTGAACTTTCAAAGCTTGCTA
TTAAATCATTTAGAATGTTTACATTTACTAAGGTGTGCTGGGTCATGTAAAATATTAGACACTAATATTTTCATAGAAATTAGGCTGGAGAAAGAAGGAA
GAAATGGTTTTCTTAAATACCTACAAAAAAGTTACTGTGGTATCTATGAGTTATCATCTTAGCTGTGTTAAAAATGAATTTTTACTATGGCAGATATGGT
ATGGATCGTAAAATTTTAAGCACTAAAAATTTTTTCATAACCTTTCATAATAAAGTTTAATAATAGGTTTATTAACTGAATTTCATTAGTTTTTTAAAAG
TGTTTTTGGTTTGTGTATATATACATATACAAATACAACATTTACAATAAATAAAATACTTGAAATTCTCTTTTGTGTCTCCTAGTAGCTTCCTACTCAA
CTATTTATAATCTCATTAATTAAAAAGTTATAATTTTAGATAAAAATTCTAGTCAAATTTTTACAGATATTATCTCACTAATTTTCAGACTTTTGCCAAA
GTGTGCACAATGGCTTTTTGTTAATAAAGAACAGATTAGTTTTGAAGAAGGCAAAAATTTCAGTTTTCTGAAGACAGCATGTTATTTTAACAATCAAGTA
TACATATTAAAAATTGTGAGCAATCTCAAATGAAGGTCCATCGTTTCATTTTAAATCTCTAAATGAATTCATATAAGACTCAAACGTTTGTGCTGTTCAC
TCATGTAGCCTCAGTTTTTGCAATTGTGATGCATATCACTGAAATTTTACAGTTGGTAATGTATTAACTATGTAACTTAACACTTGGAATTAAATAGTTC
TTTGGATATTTGACTAGTTAAGTTTTTAAAAAGACTATTGGATCTGAACTTCTTTTATATATTTTTTAATATGCTTTATGTTTTTTACTTACTTGGTCAT
GGATGCCACTTCAAAATTTGAAAATATTAAAGGACATCCTTTCTTTCTTCAAAAAGAATAAATAAGGGT
  • ADAM9.F3 (forward primer)
  • ADAM9.R3 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

FLPGGTLCRGKTSECDVPEYCNGSSQFCQPDVF
IQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKA
KAAPKDCFIEVNSKGDRFGNCGFSGNEYKKCAT
GNALCGKLQCENVQEIPVFGIVPAIIQTPSRGT
KCWGVDFQLGSDVPDPGMVNEGTKCGAGKICRNF
QCVDASVLNYDCDVQKKCHGHGVCNSNKNCHCE
NGWAPPNCETKGYGGSVDSGPTYNGKNEYCIEG
RTSGLLLPNCSPYCLCYFYLHQEGSTVEKLLQKE
EITNI*VRWQKSSKPF*TAGECSSTCFSSDTSQ
RSSYICKQICSTNLCSQATSAVPIKATSTTTES
IISGKLNSCPSCSCTSFI*FPHLIFLTFFLQMSS
GN*ANTFFFS*CFLEKPFCCNYE*KQNTTKQTS
LTQKNRN*V*EL*NTRKCSKAREFTITFPFPSL
NKSYSVIGEVNALIMDFLNMLLQ*FSN*LYWCKS
FVIKCLSVILNFLP*LSLM*FLIEHVII*YL*K
LTNQLPIISNIFHHARINNHHTLESCLSLTT*I
SKYCLQKNAQEPQLRCHIILKVQNILKECVCIHA
VTRFHFYDLSTIGNNS*RN*FNIRISIMNHVKA
*HSFTIALF*INYKL*GTKYLIDLIKYVDSWL*
*SRSNYKIFNQLNFYKTT*EFHEHFKI*TFKACY
*II*NVYIY*GVLGHVKY*TLIFS*KLGWRKKE
EMVFLNTYKKVTVVSMSYHLSCVKNEFLLWQIW
YGS*NFKH*KFFHNLS**SLIIGLLTEFH*FFKS
VFGLCIYTYTNTTFTINKILEILFCVS**LPTQ
LFIISLIKKL*F*IKILVKFLQILSH*FSDFCQ
SVHNGFLLIKNRLVLKKAKISVF*RQHVILTIKY
TY*KL*AISNEGPSFHFKSLNEFI*DSNVCAVH
SCSLSFCNCDAYH*NFTVGNVLTM*LNTWN*IV
LWIFD*LSF*KDYWI*TSFIYFLICFMFFTYLVM
DATSKFENIKGHPFFLQKE*IR

Frame 1

SFQEVLYAEEKPVSVMFQSTAMVLLSSVSQMFL
FRMDILARITKPIATTACASIMMLNVKSSLAQK
PRLPPKIVSLK*ILKVTDLAIVVSLAMNTRSVPL
GMLCVESFSVRMYKRYLYLELCLLLFKRLVEAP
NVGVWISS*DQMFQILGWLTKAQNVVLERSVET
SSV*MLLF*IMTVMFRKSVMDMGYVIAIRIVTVK
MAGLPQIVRLKDTEEVWTVDLHTMAKMNTALRD
GLLVFFFLIVPLIVCAIFIFIKRDQLWRSYFRK
KRSQTYESDGKNQANPSRQPGSVPRHVSPVTPPR
EVPIYANRFAVPTYAAKQPQQFPSRPPPPQPKV
SSQGNLIPARPAPAPPLYSSLT*FF*PSFCKCL
QGTELILFFFLDVFLKSLSVATMNENKTPQNRLH
*HRKTETECESCEIQGNAVKPGNLQ*HFRFHH*
ISLIQSSVRLMH*SWIF*TCYCSDSQINCIGVR
VLSLSV*VLF*IFYLSYH*CSSSLNM**SNTCEN
*LISCQ*YLIFFIMHELIIIIL*NLVCHSLHE*
ANIVFKRMHKNHN*DVILF*KYKIY*KSVCVFT
QLLASIFMTFQL*VITLREINLILEFLL*IM*KH
DIRSQ*HYFK*IISFKVRSI**I*SNMLIHGYN
KAGAIIKSSIN*TFTKPLENFMSTLKSELSKLA
IKSFRMFTFTKVCWVM*NIRH*YFHRN*AGERRK
KWFS*IPTKKLLWYL*VIILAVLKMNFYYGRYG
MDRKILSTKNFFITFHNKV***VY*LNFISFLK
VFLVCVYIHIQIQHLQ*IKYLKFSFVSPSSFLLN
YL*SH*LKSYNFR*KF*SNFYRYYLTNFQTFAK
VCTMAFC**RTD*F*RRQKFQFSEDSMLF*QSS
IHIKNCEQSQMKVHRFILNL*MNSYKTQTFVLFT
HVASVFAIVMHITEILQLVMY*LCNLTLGIK*F
FGYLTS*VFKKTIGSELLLYIF*YALCFLLTWS
WMPLQNLKILKDILSFFKKNK*G

Frame 2

PSRRYFMPRKNQ*V*CSRVLQWFFSVLSARCFY
SEWISLPE*QSLLLQRHVPVL*CSMSSHLWLKS
QGCPQRLFH*SEF*R*QIWQLWFLWQ*IQEVCH
WECFVWKASV*ECTRDTCIWNCACYYSNA*SRHQ
MLGCGFPARIRCSRSWDG*RRHKMWCWKDL*KL
PVCRCFCSEL*L*CSEKVSWTWGM**Q*ELSL*
KWLGSPKL*D*RIRRKCGQWTYIQWQK*ILH*GT
DFWSSSS*LFPLLSVLFLSSSRGINCGEATSER
RDHKHMSQMAKIKQTLLDSRGVFLDMFLQ*HLP
EKFLYMQTDLQYQPMQPSNLSSSHQGHLHHNRKY
HLRET*FLPVLLLHLLYIVPSLDFFNLLFANVF
RELS*YFFFFLMFS*KAFLLQL*MKTKHHKTDF
TNTEKQKLSVRVVKYKEMQ*SQGIYNNISVSIIE
*VLFSHR*G*CTNHGFFEHVIAVILKLTVLV*E
FCH*VFKCYSEFSTLVIINVVPH*TCDNLIPVK
TD*SAANNI*YFSSCTN**SSYSRILSVTHYMNK
QILSSKECTRTTIKMSYYFESTKYTKRVCVYSR
SYSLPFL*PFNYR**LLEKLI*Y*NFYYESCES
MTFVHNSTILNKL*ALRYEVFNRSNQIC*FMAII
KQEQL*NLQSIELLQNHLRIS*AL*NLNFQSLL
LNHLECLHLLRCAGSCKILDTNIFIEIRLEKEG
RNGFLKYLQKSYCGIYELSS*LC*K*IFTMADMV
WIVKF*ALKIFS*PFIIKFNNRFIN*ISLVF*K
CFWFVYIYIYKYNIYNK*NT*NSLLCLLVASYS
TIYNLIN*KVIILDKNSSQIFTDIISLIFRLLPK
CAQWLFVNKEQISFEEGKNFSFLKTACYFNNQV
YILKIVSNLK*RSIVSF*ISK*IHIRLKRLCCS
LM*PQFLQL*CISLKFYSW*CINYVT*HLELNSS
LDI*LVKFLKRLLDLNFFYIFFNMLYVFYLLGH
GCHFKI*KY*RTSFLSSKRINKG

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