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Sequences

Sequence IL1R1.fAug05

AATGTGAAAGATGATTACAGTGGCCAGAGGACTGCCAAGGCTCCTTCTCAAGCTGCTTGAGTCAATGAGGGTAGACGCACCCTCTGAAGATGGTGACTCC
C
TCCTGAGAAGCTGGACCCCTTGGTAAAAGACAAGGCCTTCTCCAAGAAGAATATGAAAGTGTTACTCAGACTTATTTGTTTCATAGCTCTACTGATTTC
TTCTCTGGAGGCTGATAAATGCAAGGAACGTGAAGAAAAAATAATTTTAGTGTCATCTGCAAATGAAATTGATGTTCGTCCCTGTCCTCTTAACCCAAAT
GAACACAAAGGCACTATAACTTGGTATAAAGATGACAGCAAGACACCTGTATCTACAGAACAAGCCTCCAGGATTCATCAACACAAAGAGAAACTTTGGT
TTGTTCCTGCTAAGGTGGAGGATTCAGGACATTACTATTGCGTGGTAAGAAATTCATCTTACTGCCTCAGAATTAAAATAAGTGCAAAATTTGTGGAGAA
TGAGCCTAACTTATGTTATAATGCACAAGCCATATTTAAGCAGAAACTACCCGTTGCAGGAGACGGAGGACTTGTGTGCCCTTATATGGAGTTTTTTAAA
AATGAAAATAATGAGTTACCTAAATTACAGTGGTATAAGAGGAAAACAAACCCACAAGGCCTGTGATTGTGAGCCCAGCTAATGAGACAATGGAAGTAGA
CTTGGGATCCCAGATACAATTGATCTGTAATGTCACCGGCCAGTTGAGTGACATTGCTTACTGGAAGTGGAATGGGTCAGTAATTGATGAAGATGACCCA
GTGCTAGGGGAAGACTATTACAGTGTGGAAAATCCTGCAAACAAAAGAAGGAGTACCCTCATCACAGTGCTTAATATATCGGAAATTGAAAGTAGATTTT
ATAAACATCCATTTACCTGTTTTGCCAAGAATACACATGGTATAGATGCAGCATATATCCAGTTAATATATCCAGTCACTAATTTCCAGAAGCACATGAT
TGGTATATGTGTCACGTTGACAGTCATAATTGTGTGTTCTGTTTTCATCTATAAAATCTTCAAGATTGACATTGTGCTTTGGTACAGGGATTCCTGCTAT
GATTTTCTCCCAATAAAAGCTTCAGATGGAAAGACCTATGACGCATATATACTGTATCCAAAGACTGTTGGGGAAGGGTCTACCTCTGACTGTGATATTT
TTGTGTTTAAAGTCTTGCCTGAGGTCTTGGAAAAACAGTGTGGATATAAGCTGTTCATTTATGGAAGGGATGACTACGTTGGGGAAGACATTGTTGAGGT
CATTAATGAAAACGTAAAGAAAAGCAGAAGACTGATTATCATTTTAGTCAGAGAAACATCAGGCTTCAGCTGGCTGGGTGGTTCATCTGAAGAGCAAATA
GCCATGTATAATGCTCTTGTTCAGGATGGAATTAAAGTTGTCCTGCTTGAGCTGGAGAAAATCCAAGACTATGAGAAAATGCCAGAATCGATTAAATTCA
TTAAGCAGAAACATGGGGCTATCCGCTGGTCAGGGGACTTTACACAGGGACCACAGTCTGCAAAGACAAGGTTCTGGAAGAATGTCAGGTACCACATGCC
AGTCCAGCGACGGTCACCTTCATCTAAACACCAGTTACTGTCACCAGCCACTAAGGAGAAACTGCAAAGAGAGGCTCACGTGCCTCTCGGGTAGCATGGA
GAAGTTGCCAAGAGTTCTTTAGGTGCCTCCTGTCTTATGGCGTTGCAGGCCAGGTTATGCCTCATGCTGACTTGCAGAGTTCATGGAATGTAACTATATC
ATCCTTTATCCCTGAGGTCACCTGGAATCAGATTATTAAGGGAATAAGCCATGACGTCAATAGCAGCCCAGGGCACTTCAGAGTAGAGGGCTTGGGAAGA
TCTTTTAAAAAGGCAGTAGGCCCGGTGTGGTGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCTGAAGTGGGTGGATCACCAGAGGTCAGGAGTTCGA
GACCAGCCCAGCCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATGAGCTAGGCATGGTGGCACACGCCTGTAATCCCAGCTACACCTGAGGC
TGAGGCAGGAGAATTGCTTGAACCGGGGAGACGGAGGTTGCAGTGAGCCGAGTTTGGGCCACTGCACTCTAGCCTGGCAACAGAGCAAGACTCCGTCTCA
AAAAAAGGGCAATAAATGCCCTCTCTGAATGTTTGAACTGCCAAGAAAAGGCATGGAGACAGCGAACTAGAAGAAAGGGCAAGAAGGAAATAGCCACCGT
CTACAGATGGCTTAGTTAAGTCATCCACAGCCCAAGGGCGGGGCTATGCCTTGTCTGGGGACCCTGTAGAGTCACTGACCCTGGAGCGGCTCTCCTGAGA
GGTGCTGCAGGCAAAGTGAGACTGACACCTCACTGAGGAAGGGAGACATATTCTTGGAGAACTTTCCATCTGCTTGTATTTTCCATACACATCCCCAGCC
AGAAGTTAGTGTCCGAAGACCGAATTTTATTTTACAGAGCTTGAAAACTCACTTCAATGAACAAAGGGATTCTCCAGGATTCCAAAGTTTTGAAGTCATC
TTAGCTTTCCACAGGAGGGAGAGAACTTAAAAAAGCAACAGTAGCAGGGAATTGATCCACTTCTTAATGCTTTCCTCCCTGGCATGACCATCCTGTCCTT
TGTTATTATCCTGCATTTTACGTCTTTGGAGGAACAGCTCCCTAGTGGCTTCCTCCGTCTGCAATGTCCCTTGCACAGCCCACACATGAACCATCCTTCC
CATGATGCCGCTCTTCTGTCATCCCGCTCCTGCTGAAACACCTCCCAGGGGCTCCACCTGTTCAGGAGCTGAAGCCCATGCTTTCCCACCAGCATGTCAC
TCCCAGACCACCTCCCTGCCCTGTCCTCCAGCTTCCCCTCGCTGTCCTGCTGTGTGAATTCCCAGGTTGGCCTGGTGGCCATGTCGCCTGCCCCCAGCAC
TCCTCTGTCTCTGCTCTTGCCTGCACCCTTCCTCCTCCTTTGCCTAGGAGGCCTTCTCGCATTTTCTCTAGCTGATCAGAATTTTACCAAAATTCAGAAC
ATCCTCCAATTCCACAGTCTCTGGGAGACTTTCCCTAAGAGGCGACTTCCTCTCCAGCCTTCTCTCTCTGGTCAGGCCCACTGCAGAGATGGTGGTGAGC
ACATCTGGGAGGCTGGTCTCCCTCCAGCTGGAATTGCTGCTCTCTGAGGGAGAGGCTGTGGTGGCTGTCTCTGTCCCTCACTGCCTTCCAGGAGCAATTT
GCACATGTAACATAGATTTATGTAATGCTTTATGTTTAAAAACATTCCCCAATTATCTTATTTAATTTTTGCAATTATTCTAATTTTATATATAGAGAAA
GTGACCTATTTTTTAAAAAAATCACACTCTAAGTTCTATTGAACCTAGGACTTGAGCCTCCATTTCTGGCTTCTAGTCTGGTGTTCTGAGTACTTGATTT
CAGGTCAATAACGGTCCCCCCTCACTCCACACTGGCACGTTTGTGAGAAGAAATGACATTTTGCTAGGAAGTGACCGAGTCTAGGAATGCTTTTATTCAA
GACACCAAATTCCAAACTTCTAAATGTTGGAATTTTCAAAAATTGTGTTTAGATTTTATGAAAAACTCTTCTACTTTCATCTATTCTTTCCCTAGAGGCA
AACATTTCTTAAAATGTTTCATTTTCATTAAAAATGAAAGCCAAATTTATATGCCACCGATTGCAGGACACAAGCACAGTTTTAAGAGTTGTATGAACAT
GGAGAGGACTTTTGGTTTTTATATTTCTCGTATTTAATATGGGTGAACACCAACTTTTATTTGGAATAATAATTTTCCTCCTAAACAAAAACACATTGAG
TTTAAGTCTCTGACTCTTGCCTTTCCACCTGCTTTCTCCTGGGCCCGCTTTGCCTGCTTGAAGGAACAGTGCTGTTCTGGAGCTGCTGTTCCAACAGACA
GGGCCTAGCTTTCATTTGACACACAGACTACAGCCAGAAGCCCATGGAGCAGGGATGTCACGTCTTGAAAAGCCTATTAGATGTTTTACAAATTTAATTT
TGCAGATTATTTTAGTCTGTCATCCAGAAAATGTGTCAGCATGCATAGTGCTAAGAAAGCAAGCCAATTTGGAAACTTAGGTTAGTGACAAAATTGGCCA
GAGAGTGGGGGTGATGATGACCAAGAATTACAAGTAGAATGGCAGCTGGAATTTAAGGAGGGACAAGAATCAATGGATAAGCGTGGGTGGAGGAAGATCC
AAACAGAAAAGTGCAAAGTTATTCCCCATCTTCCAAGGGTTGAATTCTGGAGGAAGAAGACACATTCCTAGTTCCCCGTGAACTTCCTTTGACTTATTGT
CCCCACTAAAACAAAACAAAAAACTTTTAATGCCTTCCACATTAATTAGATTTTCTTGCAGTTTTTTTATGGCATTTTTTTAAAGATGCCCTAAGTGTTG
AAGAAGAGTTTGCAAATGCAACAAAATATTTAATTACCGGTTGTTAAAACTGGTTTAGCACAATTTATATTTTCCCTCTCTTGCCTTTCTTATTTGCAAT
AAAAGGTATTGAGCCATTTTTTAAATGACATTTTTGATAAATTATGTTTGTACTAGTTGATGAAGGAGTTTTTTTTAACCTGTTTATATAATTTTGCAGC
AGAAGCCAAATTTTTTGTATATTAAAGCACCAAATTCATGTACAGCATGCATCACGGATCAATAGACTGTACTTATTTTCCAATAAAATTTTCAAACTTT
GTACTGTTA
  • IL1R1.F6 (forward primer)
  • IL1R1.R9 (reverse primer)
  • Single exon skipping

Frame 0

NVKDDYSGQRTAKAPSQAA*VNEGRRTL*RW*L
P
PEKLDPLVKDKAFSKKNMKVLLRLICFIALLIS
SLEADKCKEREEKIILVSSANEIDVRPCPLNPN
EHKGTITWYKDDSKTPVSTEQASRIHQHKEKLW
FVPAKVEDSGHYYCVVRNSSYCLRIKISAKFVEN
EPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFK
NENNELPKLQWYKRKTNPQGL*L*AQLMRQWK*
TWDPRYN*SVMSPAS*VTLLTGSGMGQ*LMKMTQ
C*GKTITVWKILQTKEGVPSSQCLIYRKLKVDF
INIHLPVLPRIHMV*MQHISS*YIQSLISRST*
LVYVSR*QS*LCVLFSSIKSSRLTLCFGTGIPAM
IFSQ*KLQMERPMTHIYCIQRLLGKGLPLTVIF
LCLKSCLRSWKNSVDISCSFMEGMTTLGKTLLR
SLMKT*RKAED*LSF*SEKHQASAGWVVHLKSK*
PCIMLLFRMELKLSCLSWRKSKTMRKCQNRLNS
LSRNMGLSAGQGTLHRDHSLQRQGSGRMSGTTC
QSSDGHLHLNTSYCHQPLRRNCKERLTCLSGSME
KLPRVL*VPPVLWRCRPGYASC*LAEFMECNYI
ILYP*GHLESDY*GNKP*RQ*QPRALQSRGLGK
IF*KGSRPGVVAHAYNPSTLGG*SGWITRGQEFE
TSPANMAKPHLY*KYKNELGMVAHACNPSYT*G
*GRRIA*TGETEVAVSRVWATAL*PGNRARLRL
KKRAINALSECLNCQEKAWRQRTRRKGKKEIATV
YRWLS*VIHSPRAGLCLVWGPCRVTDPGAALLR
GAAGKVRLTPH*GRETYSWRTFHLLVFSIHIPS
QKLVSEDRILFYRA*KLTSMNKGILQDSKVLKSS
*LSTGGRELKKATVAGN*STS*CFPPWHDHPVL
CYYPAFYVFGGTAP*WLPPSAMSLAQPTHEPSF
P*CRSSVIPLLLKHLPGAPPVQELKPMLSHQHVT
PRPPPCPVLQLPLAVLLCEFPGWPGGHVACPQH
SSVSALACTLPPPLPRRPSRIFSS*SEFYQNSE
HPPIPQSLGDFP*EATSSPAFSLWSGPLQRWW*A
HLGGWSPSSWNCCSLRERLWWLSLSLTAFQEQF
AHVT*IYVMLYV*KHSPIILFNFCNYSNFIYRE
SDLFFKKITL*VLLNLGLEPPFLASSLVF*VLDF
RSITVPPHSTLARL*EEMTFC*EVTESRNAFIQ
DTKFQTSKCWNFQKLCLDFMKNSSTFIYSFPRG
KHFLKCFIFIKNESQIYMPPIAGHKHSFKSCMNM
ERTFGFYISRI*YG*TPTFIWNNNFPPKQKHIE
FKSLTLAFPPAFSWARFACLKEQCCSGAAVPTD
RA*LSFDTQTTARSPWSRDVTS*KAY*MFYKFNF
ADYFSLSSRKCVSMHSAKKASQFGNLG**QNWP
ESGGDDDQELQVEWQLEFKEGQESMDKRGWRKI
QTEKCKVIPHLPRVEFWRKKTHS*FPVNFL*LIV
PTKTKQKTFNAFHIN*IFLQFFYGIFLKMP*VL
KKSLQMQQNI*LPVVKTGLAQFIFSLSCLSYLQ
*KVLSHFLNDIFDKLCLY*LMKEFFLTCLYNFAA
EAKFFVY*STKFMYSMHHGSIDCTYFPIKFSNF
VLL

Frame 1

M*KMITVARGLPRLLLKLLESMRVDAPSEDGDS
LLRSWTPW*KTRPSPRRI*KCYSDLFVS*LY*F
LLWRLINARNVKKK*F*CHLQMKLMFVPVLLTQM
NTKAL*LGIKMTARHLYLQNKPPGFINTKRNFG
LFLLRWRIQDITIAW*EIHLTASELK*VQNLWR
MSLTYVIMHKPYLSRNYPLQETEDLCALIWSFLK
MKIMSYLNYSGIRGKQTHKACDCEPS**DNGSR
LGIPDTIDL*CHRPVE*HCLLEVEWVSN**R*P
SARGRLLQCGKSCKQKKEYPHHSA*YIGN*K*IL
*TSIYLFCQEYTWYRCSIYPVNISSH*FPEAHD
WYMCHVDSHNCVFCFHL*NLQD*HCALVQGFLL
*FSPNKSFRWKDL*RIYTVSKDCWGRVYL*L*YF
CV*SLA*GLGKTVWI*AVHLWKG*LRWGRHC*G
H**KRKEKQKTDYHFSQRNIRLQLAGWFI*RAN
SHV*CSCSGWN*SCPA*AGENPRL*ENARID*IH
*AETWGYPLVRGLYTGTTVCKDKVLEECQVPHA
SPATVTFI*TPVTVTSH*GETAKRGSRASRVAW
RSCQEFFRCLLSYGVAGQVMPHADLQSSWNVTIS
SFIPEVTWNQIIKGISHDVNSSPGHFRVEGLGR
SFKKAVGPVWWLTPIIPALWEAEVGGSPEVRSS
RPAQPTWQNPISTKNTKMS*AWWHTPVIPATPEA
EAGELLEPGRRRLQ*AEFGPLHSSLATEQDSVS
KKGQ*MPSLNV*TAKKRHGDSELEERARRK*PP
STDGLVKSSTAQGRGYALSGDPVESLTLERLS*E
VLQAK*D*HLTEEGRHILGELSICLYFPYTSPA
RS*CPKTEFYFTELENSLQ*TKGFSRIPKF*SH
LSFPQEGENLKKQQ*QGIDPLLNAFLPGMTILSF
VIILHFTSLEEQLPSGFLRLQCPLHSPHMNHPS
HDAALLSSRSC*NTSQGLHLFRS*SPCFPTSMS
LPDHLPALSSSFPSLSCCVNSQVGLVAMSPAPST
PLSLLLPAPFLLLCLGGLLAFSLADQNFTKIQN
ILQFHSLWETFPKRRLPLQPSLSGQAHCRDGGE
HIWEAGLPPAGIAAL*GRGCGGCLCPSLPSRSNL
HM*HRFM*CFMFKNIPQLSYLIFAIILILYIEK
VTYFLKKSHSKFY*T*DLSLHFWLLVWCSEYLI
SGQ*RSPLTPHWHVCEKK*HFARK*PSLGMLLFK
TPNSKLLNVGIFKNCV*IL*KTLLLSSILSLEA
NIS*NVSFSLKMKAKFICHRLQDTSTVLRVV*T
WRGLLVFIFLVFNMGEHQLLFGIIIFLLNKNTLS
LSL*LLPFHLLSPGPALPA*RNSAVLELLFQQT
GPSFHLTHRLQPEAHGAGMSRLEKPIRCFTNLI
LQIILVCHPENVSACIVLRKQANLET*VSDKIGQ
RVGVMMTKNYK*NGSWNLRRDKNQWISVGGGRS
KQKSAKLFPIFQGLNSGGRRHIPSSP*TSFDLL
SPLKQNKKLLMPSTLIRFSCSFFMAFF*RCPKC*
RRVCKCNKIFNYRLLKLV*HNLYFPSLAFLICN
KRY*AIF*MTFLINYVCTS**RSFF*PVYIILQ
QKPNFLYIKAPNSCTACITDQ*TVLIFQ*NFQTL
YC

Frame 2

CER*LQWPEDCQGSFSSCLSQ*G*THPLKMVTP
S*EAGPLGKRQGLLQEEYESVTQTYLFHSSTDF
FSGG**MQGT*RKNNFSVICK*N*CSSLSS*PK
*TQRHYNLV*R*QQDTCIYRTSLQDSSTQRETLV
CSC*GGGFRTLLLRGKKFILLPQN*NKCKICGE
*A*LML*CTSHI*AETTRCRRRRTCVPLYGVF*
K*K**VT*ITVV*EENKPTRPVIVSPANETMEVD
LGSQIQLICNVTGQLSDIAYWKWNGSVIDEDDP
VLGEDYYSVENPANKRRSTLITVLNISEIESRF
YKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKHMI
GICVTLTVIIVCSVFIYKIFKIDIVLWYRDSCY
DFLPIKASDGKTYDAYILYPKTVGEGSTSDCDI
FVFKVLPEVLEKQCGYKLFIYGRDDYVGEDIVEV
INENVKKSRRLIIILVRETSGFSWLGGSSEEQI
AMYNALVQDGIKVVLLELEKIQDYEKMPESIKF
IKQKHGAIRWSGDFTQGPQSAKTRFWKNVRYHMP
VQRRSPSSKHQLLSPATKEKLQREAHVPLG*HG
EVAKSSLGASCLMALQARLCLMLTCRVHGM*LY
HPLSLRSPGIRLLRE*AMTSIAAQGTSE*RAWED
LLKRQ*ARCGGSRL*SQHFGRLKWVDHQRSGVR
DQPSQHGKTPSLLKIQK*ARHGGTRL*SQLHLR
LRQENCLNRGDGGCSEPSLGHCTLAWQQSKTPSQ
KKGNKCPL*MFELPRKGMETAN*KKGQEGNSHR
LQMA*LSHPQPKGGAMPCLGTL*SH*PWSGSPE
RCCRQSETDTSLRKGDIFLENFPSACIFHTHPQP
EVSVRRPNFILQSLKTHFNEQRDSPGFQSFEVI
LAFHRRERT*KSNSSRELIHFLMLSSLA*PSCP
LLLSCILRLWRNSSLVASSVCNVPCTAHT*TILP
MMPLFCHPAPAETPPRGSTCSGAEAHAFPPACH
SQTTSLPCPPASPRCPAV*IPRLAWWPCRLPPA
LLCLCSCLHPSSSFA*EAFSHFL*LIRILPKFRT
SSNSTVSGRLSLRGDFLSSLLSLVRPTAEMVVS
TSGRLVSLQLELLLSEGEAVVAVSVPHCLPGAI
CTCNIDLCNALCLKTFPNYLI*FLQLF*FYI*RK
*PIF*KNHTLSSIEPRT*ASISGF*SGVLST*F
QVNNGPPSLHTGTFVRRNDILLGSDRV*ECFYS
RHQIPNF*MLEFSKIVFRFYEKLFYFHLFFP*RQ
TFLKMFHFH*K*KPNLYATDCRTQAQF*ELYEH
GEDFWFLYFSYLIWVNTNFYLE**FSS*TKTH*
V*VSDSCLSTCFLLGPLCLLEGTVLFWSCCSNRQ
GLAFI*HTDYSQKPMEQGCHVLKSLLDVLQI*F
CRLF*SVIQKMCQHA*C*ESKPIWKLRLVTKLA
REWG***PRITSRMAAGI*GGTRING*AWVEEDP
NRKVQSYSPSSKG*ILEEEDTFLVPRELPLTYC
PH*NKTKNF*CLPH*LDFLAVFLWHFFKDALSV
EEEFANATKYLITGC*NWFSTIYIFPLLPFLFAI
KGIEPFFK*HF**IMFVLVDEGVFFNLFI*FCS
RSQIFCILKHQIHVQHASRINRLYLFSNKIFKL
CTV

Sequence IL1R1.gAug05

AATGTGAAAGATGATTACAGTGGCCAGAGGACTGCCAAGGCTCCTTCTCAAGCTGCTTGAGTCAATGAGGATGTAGAAACTGAGATCCAGTGAGATGAAG
TGATTTTCCCAAAGATACATAGATGAAGTTGAAGCTTAGCTCTTTAACCCAGGTCTGCTGGCGTCCAG
GTAGACGCACCCTCTGAAGATGGTGACTCCCT
CCTGAGAAGCTGGACCCCTTGGTAAAAGACAAGGCCTTCTCCAAGAAGAATATGAAAGTGTTACTCAGACTTATTTGTTTCATAGCTCTACTGATTTCTT
CTCTGGAGGCTGATAAATGCAAGGAACGTGAAGAAAAAATAATTTTAGTGTCATCTGCAAATGAAATTGATGTTCGTCCCTGTCCTCTTAACCCAAATGA
ACACAAAGGCACTATAACTTGGTATAAAGATGACAGCAAGACACCTGTATCTACAGAACAAGCCTCCAGGATTCATCAACACAAAGAGAAACTTTGGTTT
GTTCCTGCTAAGGTGGAGGATTCAGGACATTACTATTGCGTGGTAAGAAATTCATCTTACTGCCTCAGAATTAAAATAAGTGCAAAATTTGTGGAGAATG
AGCCTAACTTATGTTATAATGCACAAGCCATATTTAAGCAGAAACTACCCGTTGCAGGAGACGGAGGACTTGTGTGCCCTTATATGGAGTTTTTTAAAAA
TGAAAATAATGAGTTACCTAAATTACAGTGGTATAAGGATTGCAAACCTCTACTTCTTGACAATATACACTTTAGTGGAGTCAAAGATAGGCTCATCG
  • IL1R1.F6 (forward primer)
  • IL1R1.R9 (reverse primer)
  • Single exon skipping

Frame 0

NVKDDYSGQRTAKAPSQAA*VNEDVETEIQ*DE
VIFPKIHR*S*SLAL*PRSAGVQ
VDAPSEDGDSL
LRSWTPW*KTRPSPRRI*KCYSDLFVS*LY*FL
LWRLINARNVKKK*F*CHLQMKLMFVPVLLTQM
NTKAL*LGIKMTARHLYLQNKPPGFINTKRNFGL
FLLRWRIQDITIAW*EIHLTASELK*VQNLWRM
SLTYVIMHKPYLSRNYPLQETEDLCALIWSFLK
MKIMSYLNYSGIRIANLYFLTIYTLVESKIGSS

Frame 1

M*KMITVARGLPRLLLKLLESMRM*KLRSSEMK
*FSQRYIDEVEA*LFNPGLLASR
*THPLKMVTP
S*EAGPLGKRQGLLQEEYESVTQTYLFHSSTDFF
SGG**MQGT*RKNNFSVICK*N*CSSLSS*PK*
TQRHYNLV*R*QQDTCIYRTSLQDSSTQRETLV
CSC*GGGFRTLLLRGKKFILLPQN*NKCKICGE*
A*LML*CTSHI*AETTRCRRRRTCVPLYGVF*K
*K**VT*ITVV*GLQTSTS*QYTL*WSQR*AH

Frame 2

CER*LQWPEDCQGSFSSCLSQ*GCRN*DPVR*S
DFPKDT*MKLKLSSLTQVCWRP
GRRTL*RW*LP
PEKLDPLVKDKAFSKKNMKVLLRLICFIALLIS
SLEADKCKEREEKIILVSSANEIDVRPCPLNPNE
HKGTITWYKDDSKTPVSTEQASRIHQHKEKLWF
VPAKVEDSGHYYCVVRNSSYCLRIKISAKFVEN
EPNLCYNAQAIFKQKLPVAGDGGLVCPYMEFFKN
ENNELPKLQWYKDCKPLLLDNIHFSGVKDRLI

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