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Sequences

Sequence ALOX5.aAug05

ALOX5.F16 (forward primer)
ALOX5.R7 (reverse primer)
Alternative donor

Frame 0

PGPGTSGGRRLRR*MRTPGPPRRGSRRSLLPRP APCPPTRSPWPLAASGSPALTTTSTSASWARRAA ARSTCWTSPSTTTSSVARWIHTT*LWTRNWARS SWSESRSASTG*MTTGT*STSR*RRPTGTTSSS PATAGSPAMSRLS*GMDAQSWPEMTKFTFSSNTD VKNWKHGKNNIDGWSGTLASP*ASMPNATRIYP VISSLIVKKEWTLF*ITPKRWRTCSSTASCTCS SLLGMTSPTLRKSLSRSATLFLSGS*ITGRKT*C LATSS*MAATLC*SGAAQSCPRSSR*PRRW*SA AWSGSSAWSRRSSKGTFSSWTLSCWMASMPTKQ TPAHSSSWPLPSACCIRTWPTRLSPLPSSSTKSR EMRTLFSSLRMQNTTGFWPKSGCVPVTSTSTRP SPTFCEHIWCLRFLALQCTASCLLCTPFSSCWW HT*DSPLQSTPRPVSSSSASVASLTRPTPQGAVG TCRWCRGP*RT*PMPPCAFPRPSRPGAWRAKKT SPTTSTGTTGSWCGKPSGRSRPRW*TSTTRATR WWRRTRSCRTS*TMSTCTACGAASPQASPSRSRA GSSCRST*PW*SSPPPPSTPRSTSASTTGAPGS PMRPQPCEPRHRLPRAW*PLSRSWTRCPTAAAP AGIWVQCGR*ASSRKTSCSWACTQKSILSRSL*R KPWPDSARTSRPLSA*LLSATRRSSCHITTCPQ TGFRTVWPSEHTASLTVGRPAAPARWTPACLAG CLARPLGSHISSSEASTFPFIL*SSGNCID*SKC KHHRDPFYTEQDCTASCPHPAQHFHTKQQQQIT TTDRCLFLLETWDDYFLFYLCLVQFLAHSRYPI QLLLNELRIGCHKNKSVHLK

Frame 1

RGQGPVVGGGCGARCGHLDRRAEAPGARCSRGP RHALLHGHRGHWQPVVRRH*RLHLPQPRGLGGL QREAPAGQALLQRLRAWRGGFIRRDCGRGTGRDP AGQNREAQVLAE*RLVPEVHHAEDAPRGLHRVP LLPLDHRRCRGCPEGWTRKVGPR*PNSHSQATP T*RTGNTAKTISMDGVEPWLPLEHRCQMPQGFTP *YPV***KRSGLCSELLQSDGEPVHQPLHAHVP VFLE*LRRL*ENLCQDQQHYF*AGHESLAGRPD VWLPVPEWLQPCVDPALHRAAREAPGDHGDGRVQ PGAAAQLGAGGPAREHFHRGL*AAGWHRCQQNR PLHTPVPGRSHLLAV*EPGQQDCPHCHPAQPNP GR*EPYFPPFGCKIRLAFGQNLGAFQ*LPRPPDH HPPSANTSGV*GFWHCNVPPAACCAPHFQAAGG TREIHHCNQHQGP*AAHLRVWPL*QGQRHRGRW ARADGAEGHEGPDLCLPVLSRGHQGPGHGEQRRH PLLLLPGRRAPGVGSHQDVHGRGGRHLLRGRPG GGGGPGAAGLRERCLRVRHAGPQVLRLPQVGQE PGAAVGVPDRGDLHRLRPARRGQLRPVRLVLLDP QCAPNHASPATDCQGRGDH*ADRGHAARPRPLL LASGCSVGAEPVPGKRAVPGHVPRRAFYREACE GSHGPIPQEPRGHCQRDC*AQQEEAAAILLLVPR PDSEQCGHLSTLPVSLWEGQLPQPDGLQPAWQA VWPGLLAVTSLPPRPVPFHLFFDLQGTA*IDQS VNTIGTHSTQSRTAQRPVHTQLSISTPSSNSKSR PLIDVYSCWRHGMIIFCSICA*SNSLHIVGTQF NYY*MN*ELVAIKINQFI*N

Frame 2

GARDQWWEEAAALDADTWTAAPRLPALAAPAAR AMPSYTVTVATGSQWFAGTDDYIYLSLVGSAGC SEKHLLDKPFYNDFERGAVDSYDVTVDEELGEI QLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFP CYRWITGDVEVVLRDGRAKLARDDQIHILKQHR RKELETRQKQYRWMEWNPGFPLSIDAKCHKDLP RDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQ SSWNDFADFEKIFVKISNTISERVMNHWQEDLM FGYQFLNGCNPVLIRRCTELPEKLPVTTEMVEC SLERQLSLEQEVQQGNIFIVDFELLDGIDANKTD PCTLQFLAAPICLLYKNLANKIVPIAIQLNQIP GDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQT ITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVA HVRFTIAINTKAREQLICECGLFDKANATGGGG HVQMVQRAMKDLTYASLCFPEAIKARGMESKED IPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQV VEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKS REQLSEYLTVVIFTASAQHAAVNFGQYDWCSWI PNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSC WHLGAVWALSQFQENELFLGMYPEEHFIEKPVK EAMARFRKNLEAIVSVIAERNKKKQLPYYYLSP DRIPNSVAI*AHCQSHCGKASCPSQMDSSLPGRL SGQASWQSHLFLRGQYLSIYSLIFRELHRLIKV *TP*GPILHRAGLHSVLSTPSSAFPHQAATANH DH**MSILVGDMG*LFSVLFVLSPIPCT**VPNS ITIE*IKNWLP*K*ISSFKM

Sequence ALOX5.bAug05

CCGGGGCCAGGGACCAGTGGTGGGAGGAGGCTGCGGCGCTAGATGCGGACACCTGGACCGCCGCGCCGAGGCTCCCGGCGCTCGCTGCTCCCGCGGCCCG CGCCATGCCCTCCTACACGGTCACCGTGGCCACTGGCAGCCAGTGGTTCGCCGGCACTGACGACTACATCTACCTCAGCCTCGTGGGCTCGGCGGGCTGC AGCGAGAAGCACCTGCTGGACAAGCCCTTCTACAACGACTTCGAGCGTGGCGCGGTGGATTCATACGACGTGACTGTGGACGAGGAACTGGGCGAGATCC AGCTGGTCAGAATCGAGAAGCGCAAGTACTGGCTGAATGACGACTGGTACCTGAAGTACATCACGCTGAAGACGCCCCACGGGGACTACATCGAGTTCCC CTGCTACCGCTGGATCACCGGCGATGTCGAGGTTGTCCTGAGGGATGGACGCGAAACCCTACAAGCCAGAAGAGACTGGGGGCCAATATTCAACATTCTT AAAGAAAAGAATTTTCAACCCAGAATTTCATATCCAGCCAAACTAAGCTTCATAAGTGAAGGAGAAATAAAATCCTTTACAGACAAGCAAATGCTGAGAG ATTTTGTCACCACCAGGCCTGCCCTAAAAGAACTCCTGAAGGAAGCACTAAACATGGAAATGAACAACTGGTACCAGCCACTGCAAAAACATGCCACATT GTAAAGACCATCAATGCTAGGAAGAAACTGCATCAACTAATGAGCAAAATAACCATCTAACATCGTAAAGACAAGATCAAATTCACACATAACAATATTA ACCATAAATGTAAATGGGCTAAATGCTCCAATTAAAAGACACAGACTGGCAAATTGGATAAAGAGTCAAGACCCATCAGTGTGCTGTATTCAGGAAACCC ATCTCATGTGCGGAGACACACATAAGCTCAAAATAAAGGGATTGGAGGAAGATCTACCAAGCAAATGGAAAACAAAGGCAGGGGTTGCAATCCTAGTCTC TGATAAAACAGACTTTAAACCAACAAAGATCAAAAGAGACAAAGAAGGCCATTACATAATGGTAAAGGGATCAATTCAACAAGAAGAGCTAACTATCCGA AACGTATATGCACCCAATACAGGAGCACCCAGATTTATAAAGCAAGTCCTTAGAGACCTACAAAGAGACCTAGACTCCCACACAATAATAATGAGAGACT TTAACACCCCACTGTCAACATTAGACAGATCAATGAGACAGAAAGTTAACAAGGATATCCAGGAATTGAACTCAGCTCTCCAGCAAGCGGAGCTAATAGA CATCTACAGAACTCTCCACCCCAAATCAACAGAATGTACATTCTTCTCAGCACTGCATCACACCTATTCTGAAATTGACCACATAGTTGGAAGTAAAGCA CTCCTTAGCAAATGTAAAAGAACAGAAACCATAACAAACTGTCTCTCAGACCACAGTGCAATCAAACTAGAACTCAAGATTAAGAAACTCACTCAAAACC TCTCAACTACATGGACACTGAACAACCTGCACCTGAATGACTACTGGGTACATAACGAAATGAAGGCAGAAATAAAGATTTTCTTTGAAACCAATGAGAA CAAAGACACAACATACCAGAATCTCTGGGACACATTTAAAGCAGTGTGTAGAGGGAAATTTATAGCACTACATGCCCACAAGAGAAAGCAGGGAAGATCT AAAATTGACACCCTAACATCACAGTTAAAAGAACTAGAGAAGCAAGAGCAAACACATTCAAAAGCTAGCAGAAGGCAAGAAATAATTAAGATCAGAGCAG AACTGAAGGAGGTAGAGACACAAAAATCCCTTCAAAAAATCAATGAGTCCAGGAGCTGATTTTTTGAAAGGATCAACAAAATTGATAGACTGCTAGCAAG ACTAATAAAGAAGAAAAGAGAAGAATCAGCTCTCCCTCTCCCCTCTCCCCTCTCCCCTCTCTCCTCTCCCATCTCCCCTCTCCCCTCTCCCATCTCCCCT CTCCCCTCTCCCTCTCCCTCTCCCCACGGTCTCCCTCTCCCTCTCCCCACGGTCTCCCTCTCCCTCTCTTTCCACGGTCTCCCTCTGATGCCGAGCCAAA GCTGGACTGTACTGCTGCCATCTCGGCTCACTGCAACCTCCCTGCCTGATTCTCCTGCCTCAGCCTGCCGAGTGCCTGCGATTGCAGGTGCGCACCGCCA CGCCTGACTGTTTTTCATATTTTTTTGGTGGAGACGGGGTTTCGCTGTGTTGGCCAGGCTGGTCTCCAGCTCCTAACCGCGAGTGATCCGCCAGCCTCGG CCTCCCGAGGTGCCGGGATTGCAGACGGAGTCTCATTCACTCAGTGCTCAATGGTGCCCAGGCTGGGGTGCAGTGGCGTGATCTCGGCTCGCTACAACCT CCACCTCCCAGCCGCCTGCCTTGGCCTCCCAAAGTGCCGAGATTGCAGCCTCTGCCCGGCCGCCACCCCGTCTGGGAAGTGAGGAGCGTCTCTGCCTGGC CACCCATCGTCTGGGATGTAAGGAGCCCCTCTGCCTGGCTGCCCAGTCTGGAAAGTGAGGAGCGTCTCTGCCCGGCCGCCATCCTGTCTAGGAAGTGAGG AGCGTCTCTGCCTGGCCGCCCATCGTCTGGGATGAAGTGAGGAGCGTCTCTGCCCAGCCGCCCATCATCTGAGATGTGGGGAGCACCACTGCCCCACCAC CCTGTCTGGGAGGACTTGTCATTGAGAAAAATGACGAGACAAGTCTCAATCATTTTAGGAAATTTATTTGCGAAAGTTAAGGACGCATGCCCGGGAGACA GCACTATGCCTTTCTCTGAAGATGGATGGAGTGGAACCCTGGCTTCCCCTTGAGCATCGATGCCAAATGCCACAAGGATTTACCCCGTGATATCCAGTTT GATAGTGAAAAAGGAGTGGACTTTGTTCTGAATTACTCCAAAGCGATGGAGAACCTGTTCATCAACCGCTTCATGCACATGTTCCAGTCTTCTTGGAATG ACTTCGCCGACTTTGAGAAAATCTTTGTCAAGATCAGCAACACTATTTCTGAGCGGGTCATGAATCACTGGCAGGAAGACCTGATGTTTGGCTACCAGTT CCTGAATGGCTGCAACCCTGTGTTGATCCGGCGCTGCACAGAGCTGCCCGAGAAGCTCCCGGTGACCACGGAGATGGTAGAGTGCAGCCTGGAGCGGCAG CTCAGCTTGGAGCAGGAGGTCCAGCAAGGGAACATTTTCATCGTGGACTTTGAGCTGCTGGATGGCATCGATGCCAACAAAACAGACCCCTGCACACTCC AGTTCCTGGCCGCTCCCATCTGCTTGCTGTATAAGAACCTGGCCAACAAGATTGTCCCCATTGCCATCCAGCTCAACCAAATCCCGGGAGATGAGAACCC TATTTTCCTCCCTTCGGATGCAAAATACGACTGGCTTTTGGCCAAAATCTGGGTGCGTTCCAGTGACTTCCACGTCCACCAGACCATCACCCACCTTCTG CGAACACATCTGGTGTCTGAGGTTTTTGGCATTGCAATGTACCGCCAGCTGCCTGCTGTGCACCCCATTTTCAAGCTGCTGGTGGCACACGTGAGATTCA CCATTGCAATCAACACCAAGGCCCGTGAGCAGCTCATCTGCGAGTGTGGCCTCTTTGACAAGGTGGGTGCCCTCCTACCCTACTTGTTGCCTGGAAGAGC CCAGCCTGGCCGCCTTCACTCCCTATCTGAGATCTAGACACCCTTTCAGGAGGCCTGGAAGGGTGAAGGCTGGAGTCTGCTCAGAGCACTGGCTCCAGCA TCCTCCTGATGTCTCCAGCCCGTGCCATTCAGCCAGGAGCACTCCTCCAGGCGCACCACCAGGCCAACGCCACAGGGGGCGGTGGGCACGTGCAGATGGT GCAGAGGGCCATGAAGGACCTGACCTATGCCTCCCTGTGCTTTCCCGAGGCCATCAAGGCCCGGGGCATGGAGAGCAAAGAAGACATCCCCTACTACTTC TACCGGGACGACGGGCTCCTGGTGTGGGAAGCCATCAGGACGTGAGCGCCCGCGGGGCGGTGGTCCTGGGGGAGGAGCCGGGACCCCTGCCTGACTACCT GGGGCGGGCCTGGCCCCTCCACCGCTAGCGCTGAATGGGGACGGGGTGGGGGAGTCCCAGCGTCCGTGAGGGGGTTGCCGCCGGGCACCGCTCCGCAGAC CTGGCTGGGTCGCCCACCCCGGCTGCGCCCCCTGAGCCAGGTTCACGGCCGAGGTGGTAGACATCTACTACGAGGGCGACCAGGTGGTGGAGGAGGACCC GGAGCTGCAGGACTTCGTGAACGATGTCTACGTGTACGGCATGCGGGGCCGCAAGTCCTCAGGCTTCCCCAAGTCGGTCAAGAGCCGGGAGCAGCTGTCG GAGTACCTGACCGTGGTGATCTTCACCGCCTCCGCCCAGCACGCCGCGGTCAACTTCGGCCAGTACGACTGGTGCTCCTGGATCCCCAATGCGCCCCCAA CCATGCGAGCCCCGCCACCGACTGCCAAGGGCGTGGTGACCATTGAGCAGATCGTGGACACGCTGCCCGACCGCGGCCGCTCCTGCTGGCATCTGGGTGC AGTGTGGGCGCTGAGCCAGTTCCAGGAAAACGAGGTGAAGCTGGGCAGGGCGGGGCACAGCCCCAGGTCACCCCAGGTTAAGCGGTTCCTCAGCCTCAGG GCTTTGTGACTCGGGCCCCAAGGCTCACTTGGAGCAAAGGAATCCTGACTTCCAAGGCTGGAAGGGCCCAGAAGGCTGCAGCCGCCACCAGGTCCCCCGG CCTCAGCCTGGACAGAGCTCAGGGTGTGCAGGGCAGGAGAGCACACAGCCCAGGCTTTGCTCACTGTCACCAGAGGGTCGTGTGTGACGCCCCCTCCCCC CAGCTATTGACAAAGTTCTTGCACATGTGTTTTACCCTGGTACTCCAGAGGGAATGACCAAGAGTTTCCTGGGTTCCTTCCGGACACGTGCATCTCATTT AACCTAACAACTGAATCCGGTGTGTCTTCGTGGATGCACCCGCTTTGGGGTAGCTCAGTACTGCATAGAATGGCCGGACCAGTCCAACCTGCTCCAGACT GCTGGGTGTCTGAGTTGTTCCCGGCCAATGTGTTGGTCCCTCACTGGACATCCTTGTTTTTGTGGCTTTGCACATGTGTTCAGTATGACCGCACACATTC CTAGCAGACAAATTCCTTGGTCAAAGAATATTGATACTGAATTGCCCTCCACAAACTAAATTCAAAATCCCATTATCAATAGCCTATGTTTCTTGGACCT TTCCAGCTCAGAAGCTTTGTGATCTTAATCCAATACAGTATTTTTTTAAAATGATATCTAGCTCTGCCCCGCAGACATCTGTGTGAGAATGCAAATAAGC ACAGGACCCCAACAGGGCAGCCACCCCTTCAGGCTCCCTGGCCCGCTTTCTGCCTTCCTGGGCTGGAGAGGCCAGTGCTGGCCCCAGCGCCCCTGATGGG AGGTGAGAGTGCTGCGCAGGGGTGGCCCAAGACAGCAGGATACCATGGCTGCAAACACCAGCAGCCCCCAGCTTCATCTGCATCATCTCGTAACCACTTG GCAGCAGGCAGTTATTTTCCCACTTATCCATGAAGCCCCAGCCCTGGAGCCTTCCTTAGAGAAGCAGGTTGGAGGCGACGACACTTGCCTTCCCGAGGCC CTCTTGTCAGGCAGCAGAGGGTGAATATGGGGAGGTGAATAGATGCTCCCTCCTTCATCTCCCAAACGGTGGCTGGCCCCTTGGGATGAGACAGGCCTGT CAGTTTACACGGGTAGTGGATTGACCTATGTGTGTGTCCATGTCTGGGCCCTCAGCTGTTCCTGGGCATGTACCCAGAAGAGCATTTTATCGAGAAGCCT GTGAAGGAAGCCATGGCCCGATTCCGCAAGAACCTCGAGGCCATTGTCAGCGTGATTGCTGAGCGCAACAAGAAGAAGCAGCTGCCATATTAC

ALOX5.F16 (forward primer)
ALOX5.R7 (reverse primer)
Alternative donor

Frame 0

PGPGTSGGRRLRR*MRTPGPPRRGSRRSLLPRP APCPPTRSPWPLAASGSPALTTTSTSASWARRAA ARSTCWTSPSTTTSSVARWIHTT*LWTRNWARS SWSESRSASTG*MTTGT*STSR*RRPTGTTSSS PATAGSPAMSRLS*GMDAKPYKPEETGGQYSTFL KKRIFNPEFHIQPN*AS*VKEK*NPLQTSKC*E ILSPPGLP*KNS*RKH*TWK*TTGTSHCKNMPH CKDHQC*EETASTNEQNNHLTS*RQDQIHT*QY* P*M*MG*MLQLKDTDWQIG*RVKTHQCAVFRKP ISCAETHISSK*RDWRKIYQANGKQRQGLQS*S LIKQTLNQQRSKETKKAIT*W*RDQFNKKS*LSE TYMHPIQEHPDL*SKSLETYKET*TPTQ***ET LTPHCQH*TDQ*DRKLTRISRN*TQLSSKRS** TSTELSTPNQQNVHSSQHCITPILKLTT*LEVKH SLANVKEQKP*QTVSQTTVQSN*NSRLRNSLKT SQLHGH*TTCT*MTTGYITK*RQK*RFSLKPMR TKTQHTRISGTHLKQCVEGNL*HYMPTRESREDL KLTP*HHS*KN*RSKSKHIQKLAEGKK*LRSEQ N*RR*RHKNPFKKSMSPGADFLKGSTKLIDC*Q D**RRKEKNQLSLSPLPSPLSPLPSPLSPLPSPL SPLPLPLPTVSLSLSPRSPSPSLSTVSL*CRAK AGLYCCHLGSLQPPCLILLPQPAECLRLQVRTA TPDCFSYFFGGDGVSLCWPGWSPAPNRE*SASLG LPRCRDCRRSLIHSVLNGAQAGVQWRDLGSLQP PPPSRLPWPPKVPRLQPLPGRHPVWEVRSVSAW PPIVWDVRSPSAWLPSLESEERLCPAAILSRK*G ASLPGRPSSGMK*GASLPSRPSSEMWGAPLPHH PVWEDLSLRKMTRQVSIILGNLFAKVKDACPGD STMPFSEDGWSGTLASP*ASMPNATRIYPVISSL IVKKEWTLF*ITPKRWRTCSSTASCTCSSLLGM TSPTLRKSLSRSATLFLSGS*ITGRKT*CLATS S*MAATLC*SGAAQSCPRSSR*PRRW*SAAWSGS SAWSRRSSKGTFSSWTLSCWMASMPTKQTPAHS SSWPLPSACCIRTWPTRLSPLPSSSTKSREMRT LFSSLRMQNTTGFWPKSGCVPVTSTSTRPSPTFC EHIWCLRFLALQCTASCLLCTPFSSCWWHT*DS PLQSTPRPVSSSSASVASLTRWVPSYPTCCLEE PSLAAFTPYLRSRHPFRRPGRVKAGVCSEHWLQH PPDVSSPCHSARSTPPGAPPGQRHRGRWARADG AEGHEGPDLCLPVLSRGHQGPGHGEQRRHPLLL LPGRRAPGVGSHQDVSARGAVVLGEEPGPLPDYL GRAWPLHR*R*MGTGWGSPSVREGVAAGHRSAD LAGSPTPAAPPEPGSRPRW*TSTTRATRWWRRT RSCRTS*TMSTCTACGAASPQASPSRSRAGSSCR ST*PW*SSPPPPSTPRSTSASTTGAPGSPMRPQ PCEPRHRLPRAW*PLSRSWTRCPTAAAPAGIWV QCGR*ASSRKTR*SWAGRGTAPGHPRLSGSSASG LCDSGPKAHLEQRNPDFQGWKGPEGCSRHQVPR PQPGQSSGCAGQESTQPRLCSLSPEGRV*RPLP PAIDKVLAHVFYPGTPEGMTKSFLGSFRTRASHL T*QLNPVCLRGCTRFGVAQYCIEWPDQSNLLQT AGCLSCSRPMCWSLTGHPCFCGFAHVFSMTAHI PSRQIPWSKNIDTELPSTN*IQNPIINSLCFLDL SSSEAL*S*SNTVFF*NDI*LCPADICVRMQIS TGPQQGSHPFRLPGPLSAFLGWRGQCWPQRP*W EVRVLRRGGPRQQDTMAANTSSPQLHLHHLVTTW QQAVIFPLIHEAPALEPSLEKQVGGDDTCLPEA LLSGSRG*IWGGE*MLPPSSPKRWLAPWDETGL SVYTGSGLTYVCVHVWALSCSWACTQKSILSRSL *RKPWPDSARTSRPLSA*LLSATRRSSCHI

Frame 1

RGQGPVVGGGCGARCGHLDRRAEAPGARCSRGP RHALLHGHRGHWQPVVRRH*RLHLPQPRGLGGL QREAPAGQALLQRLRAWRGGFIRRDCGRGTGRDP AGQNREAQVLAE*RLVPEVHHAEDAPRGLHRVP LLPLDHRRCRGCPEGWTRNPTSQKRLGANIQHS *RKEFSTQNFISSQTKLHK*RRNKILYRQANAER FCHHQACPKRTPEGSTKHGNEQLVPATAKTCHI VKTINARKKLHQLMSKITI*HRKDKIKFTHNNI NHKCKWAKCSN*KTQTGKLDKESRPISVLYSGNP SHVRRHT*AQNKGIGGRSTKQMENKGRGCNPSL **NRL*TNKDQKRQRRPLHNGKGINSTRRANYP KRICTQYRSTQIYKASP*RPTKRPRLPHNNNERL *HPTVNIRQINETES*QGYPGIELSSPASGANR HLQNSPPQINRMYILLSTASHLF*N*PHSWK*S TP*QM*KNRNHNKLSLRPQCNQTRTQD*ETHSKP LNYMDTEQPAPE*LLGT*RNEGRNKDFL*NQ*E QRHNIPESLGHI*SSV*REIYSTTCPQEKAGKI *N*HPNITVKRTREARANTFKS*QKARNN*DQSR TEGGRDTKIPSKNQ*VQELIF*KDQQN**TASK TNKEEKRRISSPSPLSPLPSLLSHLPSPLSHLP SPLSLSLSPRSPSPSPHGLPLPLFPRSPSDAEPK LDCTAAISAHCNLPA*FSCLSLPSACDCRCAPP RLTVFHIFLVETGFRCVGQAGLQLLTASDPPAS ASRGAGIADGVSFTQCSMVPRLGCSGVISARYNL HLPAACLGLPKCRDCSLCPAATPSGK*GASLPG HPSSGM*GAPLPGCPVWKVRSVSARPPSCLGSE ERLCLAAHRLG*SEERLCPAAHHLRCGEHHCPTT LSGRTCH*EK*RDKSQSF*EIYLRKLRTHARET ALCLSLKMDGVEPWLPLEHRCQMPQGFTP*YPV ***KRSGLCSELLQSDGEPVHQPLHAHVPVFLE* LRRL*ENLCQDQQHYF*AGHESLAGRPDVWLPV PEWLQPCVDPALHRAAREAPGDHGDGRVQPGAA AQLGAGGPAREHFHRGL*AAGWHRCQQNRPLHTP VPGRSHLLAV*EPGQQDCPHCHPAQPNPGR*EP YFPPFGCKIRLAFGQNLGAFQ*LPRPPDHHPPS ANTSGV*GFWHCNVPPAACCAPHFQAAGGTREIH HCNQHQGP*AAHLRVWPL*QGGCPPTLLVAWKS PAWPPSLPI*DLDTLSGGLEG*RLESAQSTGSS ILLMSPARAIQPGALLQAHHQANATGGGGHVQMV QRAMKDLTYASLCFPEAIKARGMESKEDIPYYF YRDDGLLVWEAIRT*APAGRWSWGRSRDPCLTT WGGPGPSTASAEWGRGGGVPASVRGLPPGTAPQT WLGRPPRLRPLSQVHGRGGRHLLRGRPGGGGGP GAAGLRERCLRVRHAGPQVLRLPQVGQEPGAAV GVPDRGDLHRLRPARRGQLRPVRLVLLDPQCAPN HASPATDCQGRGDH*ADRGHAARPRPLLLASGC SVGAEPVPGKRGEAGQGGAQPQVTPG*AVPQPQ GFVTRAPRLTWSKGILTSKAGRAQKAAAATRSPG LSLDRAQGVQGRRAHSPGFAHCHQRVVCDAPSP QLLTKFLHMCFTLVLQRE*PRVSWVPSGHVHLI *PNN*IRCVFVDAPALG*LSTA*NGRTSPTCSRL LGV*VVPGQCVGPSLDILVFVALHMCSV*PHTF LADKFLGQRILILNCPPQTKFKIPLSIAYVSWT FPAQKLCDLNPIQYFFKMISSSAPQTSV*ECK*A QDPNRAATPSGSLARFLPSWAGEASAGPSAPDG R*ECCAGVAQDSRIPWLQTPAAPSFICIIS*PL GSRQLFSHLSMKPQPWSLP*RSRLEATTLAFPRP SCQAAEGEYGEVNRCSLLHLPNGGWPLGMRQAC QFTRVVD*PMCVSMSGPSAVPGHVPRRAFYREA CEGSHGPIPQEPRGHCQRDC*AQQEEAAAIL

Frame 2

GARDQWWEEAAALDADTWTAAPRLPALAAPAAR AMPSYTVTVATGSQWFAGTDDYIYLSLVGSAGC SEKHLLDKPFYNDFERGAVDSYDVTVDEELGEI QLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFP CYRWITGDVEVVLRDGRETLQARRDWGPIFNIL KEKNFQPRISYPAKLSFISEGEIKSFTDKQMLR DFVTTRPALKELLKEALNMEMNNWYQPLQKHATL *RPSMLGRNCIN**AK*PSNIVKTRSNSHITIL TINVNGLNAPIKRHRLANWIKSQDPSVCCIQET HLMCGDTHKLKIKGLEEDLPSKWKTKAGVAILVS DKTDFKPTKIKRDKEGHYIMVKGSIQQEELTIR NVYAPNTGAPRFIKQVLRDLQRDLDSHTIIMRD FNTPLSTLDRSMRQKVNKDIQELNSALQQAELID IYRTLHPKSTECTFFSALHHTYSEIDHIVGSKA LLSKCKRTETITNCLSDHSAIKLELKIKKLTQN LSTTWTLNNLHLNDYWVHNEMKAEIKIFFETNEN KDTTYQNLWDTFKAVCRGKFIALHAHKRKQGRS KIDTLTSQLKELEKQEQTHSKASRRQEIIKIRA ELKEVETQKSLQKINESRS*FFERINKIDRLLAR LIKKKREESALPLPSPLSPLSSPISPLPSPISP LPSPSPSPHGLPLPLPTVSLSLSFHGLPLMPSQ SWTVLLPSRLTATSLPDSPASACRVPAIAGAHRH A*LFFIFFWWRRGFAVLARLVSSS*PRVIRQPR PPEVPGLQTESHSLSAQWCPGWGAVA*SRLATT STSQPPALASQSAEIAASARPPPRLGSEERLCLA THRLGCKEPLCLAAQSGK*GASLPGRHPV*EVR SVSAWPPIVWDEVRSVSAQPPII*DVGSTTAPP PCLGGLVIEKNDETSLNHFRKFICES*GRMPGRQ HYAFL*RWMEWNPGFPLSIDAKCHKDLPRDIQF DSEKGVDFVLNYSKAMENLFINRFMHMFQSSWN DFADFEKIFVKISNTISERVMNHWQEDLMFGYQF LNGCNPVLIRRCTELPEKLPVTTEMVECSLERQ LSLEQEVQQGNIFIVDFELLDGIDANKTDPCTL QFLAAPICLLYKNLANKIVPIAIQLNQIPGDENP IFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLL RTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRF TIAINTKAREQLICECGLFDKVGALLPYLLPGRA QPGRLHSLSEI*TPFQEAWKGEGWSLLRALAPA SS*CLQPVPFSQEHSSRRTTRPTPQGAVGTCRW CRGP*RT*PMPPCAFPRPSRPGAWRAKKTSPTTS TGTTGSWCGKPSGRERPRGGGPGGGAGTPA*LP GAGLAPPPLALNGDGVGESQRP*GGCRRAPLRR PGWVAHPGCAP*ARFTAEVVDIYYEGDQVVEEDP ELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLS EYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPP TMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGA VWALSQFQENEVKLGRAGHSPRSPQVKRFLSLR AL*LGPQGSLGAKES*LPRLEGPRRLQPPPGPP ASAWTELRVCRAGEHTAQALLTVTRGSCVTPPPP SY*QSSCTCVLPWYSRGNDQEFPGFLPDTCISF NLTTESGVSSWMHPLWGSSVLHRMAGPVQPAPD CWVSELFPANVLVPHWTSLFLWLCTCVQYDRTHS *QTNSLVKEY*Y*IALHKLNSKSHYQ*PMFLGP FQLRSFVILIQYSIFLK*YLALPRRHLCENANK HRTPTGQPPLQAPWPAFCLPGLERPVLAPAPLMG GESAAQGWPKTAGYHGCKHQQPPASSASSRNHL AAGSYFPTYP*SPSPGAFLREAGWRRRHLPSRG PLVRQQRVNMGR*IDAPSFISQTVAGPLG*DRPV SLHG*WIDLCVCPCLGPQLFLGMYPEEHFIEKP VKEAMARFRKNLEAIVSVIAERNKKKQLPYY