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Sequences

Sequence POLB.hAug05

POLB.F7 (forward primer)
POLB.R13 (reverse primer)
Single exon skipping

Frame 0

NKRRAPRPPSGATIVPPVAPELGCSCSRLQVLV PPSSWERALVPGSEHSGVLGCRPP*ANGRRRRRL STGESPTCSQKSSICYSKIPTQNKEWS*S*EIA WSRNKNC*KD**VFSNWKIT*TGKDFFFS*RFG RMIRVHPSIS*LELVALVHLLQGSL*MKELKH*K ISEKMKIN*TIISELG*NILGTLKKEFLVKRCY KCKILY*MKLKKWILNTLLQSVAVSEEVQSPVV TWMFS*PIPASLQNQPNSQNCYIRLWSSYKRFIL SQIPCQRVRQ

Frame 1

TSAVRPAPHRGQPLFRRSRRSWVAPAPVSKSWY LLQAGRGL*SLVLNTLGFSGAGRHEQTEGAAGD SQRGNHRHAHRKAASVIAKYPHKIKSGAEAKKLP GVGTKIAEKIDEFLATGKLRKLEKTFFFLKDSA G*YEFIHQFPDSS*WHWSICCKEVCR*RN*NTR RSQKK*R*IEPSSANWAEIFWGL*KKNSS*RDVT NARYCTK*S*KSGF*IHCYSLWQFQKRCRVQW* HGCSPDPSQLHFRINQTAKTVTSGCGAVTKGSF YHRYPVKG*D

Frame 2

QAPCAPPPIGGNHCSAGRAGAGLLLLPSPSPGT SFKLGEGSSPWF*TLWGSRVQAAMSKRKAPQET LNGGITDMLTEKQHLL*QNTHTK*RVELKLRNC LE*EQKLLKRLMSF*QLENYVNWKRLFFFLKIRQ DDTSSSINFLTRVSGIGPSAARKFVDEGIKTLE DLRKNEDKLNHHQRIGLKYFGDFEKRIPREEML QMQDIVLNEVKKVDSEYIATVCGSFRRGAESSGD MDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHF ITDTLSKGET

Sequence POLB.gAug05

POLB.F7 (forward primer)
POLB.R13 (reverse primer)
Single exon skipping

Frame 0

NKRRAPRPPSGATIVPPVAPELGCSCSRLQVLV PPSSWERALVPGSEHSGVLGCRPP*ANGRRRRRL STGESPTCSQKSSICYSKIPTQNKEWS*S*EIA WSRNKNC*KD**VFSNWKIT*TGKDSAG*YEFI HQFPDSS*WHWSICCKEVCR*RN*NTRRSQKK*R *IEPSSANWAEIFWGL*KKNSS*RDVTNARYCT K*S*KSGF*IHCYSLWQFQKRFCCLHQYT*IVG QKIEIF*LILTMKHSEIE

Frame 1

TSAVRPAPHRGQPLFRRSRRSWVAPAPVSKSWY LLQAGRGL*SLVLNTLGFSGAGRHEQTEGAAGD SQRGNHRHAHRKAASVIAKYPHKIKSGAEAKKLP GVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSS INFLTRVSGIGPSAARKFVDEGIKTLEDLRKNE DKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVL NEVKKVDSEYIATVCGSFRRDSAVYINTPE*LD RKLKSFN*F*L*STVK*K

Frame 2

QAPCAPPPIGGNHCSAGRAGAGLLLLPSPSPGT SFKLGEGSSPWF*TLWGSRVQAAMSKRKAPQET LNGGITDMLTEKQHLL*QNTHTK*RVELKLRNC LE*EQKLLKRLMSF*QLENYVNWKRFGRMIRVHP SIS*LELVALVHLLQGSL*MKELKH*KISEKMK IN*TIISELG*NILGTLKKEFLVKRCYKCKILY *MKLKKWILNTLLQSVAVSEEILLSTSIHLNSWT EN*NLLTNSNYEAQ*NR

Sequence POLB.dAug05

AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTAC CTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACT CTCAACGGGGGAATCACCGACATGCTCACAGAAAAGCAGCATCTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCC TGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTTAGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGAGTTCATCC ATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCTGCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAGATCTCAGAAAAAATGAAG ATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACT AAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACC CATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTGTTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAA AGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGA TCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTAC ACCATCCGTCCCTTGGGAGTCACTG

POLB.F7 (forward primer)
POLB.R13 (reverse primer)
Single exon skipping

Frame 0

Frame 1

Frame 2

Sequence POLB.cAug05

AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTAC CTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACT CTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCAT CTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTT AGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCT GCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTG GGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGT CTGTGGCAGTTTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGGGTGTTTGC CAGCTTCCCAGTAAAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCA CTGGGAGTGATATTTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGAGT TGCAGGAGAACCCCTGCCAGTGGATAGTGAAAAAGACATCTTTGATTACATCCAGTGGAAATACCGGGAACCCAAGGACCGGAGCGAATGAGGCCTGTAT CCTCCCTGGCAGACACAACCCAATAGGAGTCTTAATTTATTTCTTAACCTTTGCTATGTAAGGGTCTTTGGTGTTTTTAAATGATTGTTTCTTCTTCATG CTTTTGCTTGCAATGTAGTCAATAAAACCTCATGTACTATTATTGGATGAT

POLB.F7 (forward primer)
POLB.R13 (reverse primer)
Single exon skipping

Frame 0

NKRRAPRPPSGATIVPPVAPELGCSCSRLQVLV PPSSWERALVPGSEHSGVLGCRPP*ANGRRRRRL STGESPTCSQNSQTLRRT*AKLSTSTMLTEKQH LL*QNTHTK*RVELKLRNCLE*EQKLLKRLMSF *QLENYVNWKRFGRMIRVHPSIS*LELVALVHLL QGSL*MKELKH*KISEKMKIN*TIISELG*NIL GTLKKEFLVKRCYKCKILY*MKLKKWILNTLLQ SVAVSEEVQSPVVTWMFS*PIPASLQNQPNRVFA SFPVKMMKKNIHTEELISG*YPKISITVVFSIS LGVIFSIRI*GLMP*KRVSQSMSTPSVPWESLE LQENPCQWIVKKTSLITSSGNTGNPRTGANEACI LPGRHNPIGVLIYFLTFAM*GSLVFLNDCFFFM LLLAM*SIKPHVLLLDD

Frame 1

TSAVRPAPHRGQPLFRRSRRSWVAPAPVSKSWY LLQAGRGL*SLVLNTLGFSGAGRHEQTEGAAGD SQRGNHRHAHRTRKL*EEREPSYPQVQCLQKSSI CYSKIPTQNKEWS*S*EIAWSRNKNC*KD**VF SNWKIT*TGKDSAG*YEFIHQFPDSS*WHWSIC CKEVCR*RN*NTRRSQKK*R*IEPSSANWAEIFW GL*KKNSS*RDVTNARYCTK*S*KSGF*IHCYS LWQFQKRCRVQW*HGCSPDPSQLHFRINQTGCL PASQ*K**KRISTQKN*YQVDTQRSVLLWCSLFH WE*YFQ*EYEGSCPRKGFHNQ*VHHPSLGSHWS CRRTPASG**KRHL*LHPVEIPGTQGPERMRPV SSLADTTQ*ES*FIS*PLLCKGLWCF*MIVSSSC FCLQCSQ*NLMYYYWM

Frame 2

QAPCAPPPIGGNHCSAGRAGAGLLLLPSPSPGT SFKLGEGSSPWF*TLWGSRVQAAMSKRKAPQET LNGGITDMLTELANFEKNVSQAIHKYNAYRKAA SVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFL ATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSA ARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYF GDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATV CGSFRRGAESSGDMDVLLTHPSFTSESTKQGVC QLPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYF TGSDIFNKNMRAHALEKGFTINEYTIRPLGVTGV AGEPLPVDSEKDIFDYIQWKYREPKDRSE*GLY PPWQTQPNRSLNLFLNLCYVRVFGVFK*LFLLH AFACNVVNKTSCTIIG*

Sequence POLB.bAug05

AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTAC CTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACT CTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCAT CTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTT AGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCT GCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAGGCTCACAGCTGGATTCATGCCCAGTAAAGGGACACCTGAATGGAACTGAGTCACTTTTAG ACTTAATATGGGATGTTATGACAATTCTTAAGTTAAAAAATGCAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATA TTTTGGGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCT ACAGTCTGTGGCAGTTTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAA AACTGTTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGAGTTGCAGGAGAACCC CTGCCAGTGGATAGTGAAAAAGACATCTTTGATTACATCCAGTGGAAATACCGGGAACCCAAGGACCGGAGCGAATGAGGCCTGTATCCTCCCTGGCAGA CACAACCCAATAGGAGTCTTAATTTATTTCTTAACCTTTGCTATGTAAGGGTCTTTGGTGTTTTTAAATGATTGTTTCTTCTTCATGCTTTTGCTTGCAA TGTAGTCAATAAAACCTCATGTACTATTATTGGATGAT

POLB.F7 (forward primer)
POLB.R13 (reverse primer)
Single exon skipping

Frame 0

NKRRAPRPPSGATIVPPVAPELGCSCSRLQVLV PPSSWERALVPGSEHSGVLGCRPP*ANGRRRRRL STGESPTCSQNSQTLRRT*AKLSTSTMLTEKQH LL*QNTHTK*RVELKLRNCLE*EQKLLKRLMSF *QLENYVNWKRFGRMIRVHPSIS*LELVALVHLL QGSL*MKELKH*KAHSWIHAQ*RDT*MELSHF* T*YGML*QFLS*KMQISEKMKIN*TIISELG*N ILGTLKKEFLVKRCYKCKILY*MKLKKWILNTLL QSVAVSEEVQSPVVTWMFS*PIPASLQNQPNSQ NCYIRLWSSYKRFILSQIPCQRVRQSSWSCRRT PASG**KRHL*LHPVEIPGTQGPERMRPVSSLAD TTQ*ES*FIS*PLLCKGLWCF*MIVSSSCFCLQ CSQ*NLMYYYWM

Frame 1

TSAVRPAPHRGQPLFRRSRRSWVAPAPVSKSWY LLQAGRGL*SLVLNTLGFSGAGRHEQTEGAAGD SQRGNHRHAHRTRKL*EEREPSYPQVQCLQKSSI CYSKIPTQNKEWS*S*EIAWSRNKNC*KD**VF SNWKIT*TGKDSAG*YEFIHQFPDSS*WHWSIC CKEVCR*RN*NTRRLTAGFMPSKGTPEWN*VTFR LNMGCYDNS*VKKCRSQKK*R*IEPSSANWAEI FWGL*KKNSS*RDVTNARYCTK*S*KSGF*IHC YSLWQFQKRCRVQW*HGCSPDPSQLHFRINQTAK TVTSGCGAVTKGSFYHRYPVKG*DKVHGVAGEP LPVDSEKDIFDYIQWKYREPKDRSE*GLYPPWQ TQPNRSLNLFLNLCYVRVFGVFK*LFLLHAFACN VVNKTSCTIIG*

Frame 2

QAPCAPPPIGGNHCSAGRAGAGLLLLPSPSPGT SFKLGEGSSPWF*TLWGSRVQAAMSKRKAPQET LNGGITDMLTELANFEKNVSQAIHKYNAYRKAA SVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFL ATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSA ARKFVDEGIKTLEGSQLDSCPVKGHLNGTESLL DLIWDVMTILKLKNADLRKNEDKLNHHQRIGLKY FGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIA TVCGSFRRGAESSGDMDVLLTHPSFTSESTKQP KLLHQVVEQLQKVHFITDTLSKGETKFMELQENP CQWIVKKTSLITSSGNTGNPRTGANEACILPGR HNPIGVLIYFLTFAM*GSLVFLNDCFFFMLLLA M*SIKPHVLLLDD

Sequence POLB.aAug05

AACAAGCGCCGTGCGCCCCGCCCCCCATCGGGGGCAACCATTGTTCCGCCGGTCGCGCCGGAGCTGGGTTGCTCCTGCTCCCGTCTCCAAGTCCTGGTAC CTCCTTCAAGCTGGGAGAGGGCTCTAGTCCCTGGTTCTGAACACTCTGGGGTTCTCGGGTGCAGGCCGCCATGAGCAAACGGAAGGCGCCGCAGGAGACT CTCAACGGGGGAATCACCGACATGCTCACAGAACTCGCAAACTTTGAGAAGAACGTGAGCCAAGCTATCCACAAGTACAATGCTTACAGAAAAGCAGCAT CTGTTATAGCAAAATACCCACACAAAATAAAGAGTGGAGCTGAAGCTAAGAAATTGCCTGGAGTAGGAACAAAAATTGCTGAAAAGATTGATGAGTTTTT AGCAACTGGAAAATTACGTAAACTGGAAAAGATTCGGCAGGATGATACGAGTTCATCCATCAATTTCCTGACTCGAGTTAGTGGCATTGGTCCATCTGCT GCAAGGAAGTTTGTAGATGAAGGAATTAAAACACTAGAAGATCTCAGAAAAAATGAAGATAAATTGAACCATCATCAGCGAATTGGGCTGAAATATTTTG GGGACTTTGAAAAAAGAATTCCTCGTGAAGAGATGTTACAAATGCAAGATATTGTACTAAATGAAGTTAAAAAAGTGGATTCTGAATACATTGCTACAGT CTGTGGCAGTTTCAGAAGAGGTGCAGAGTCCAGTGGTGACATGGATGTTCTCCTGACCCATCCCAGCTTCACTTCAGAATCAACCAAACAGCCAAAACTG TTACATCAGGTTGTGGAGCAGTTACAAAAGGTTCATTTTATCACAGATACCCTGTCAAAGGGTGAGACAAAGTTCATGGGTGTTTGCCAGCTTCCCAGTA AAAATGATGAAAAAGAATATCCACACAGAAGAATTGATATCAGGTTGATACCCAAAGATCAGTATTACTGTGGTGTTCTCTATTTCACTGGGAGTGATAT TTTCAATAAGAATATGAGGGCTCATGCCCTAGAAAAGGGTTTCACAATCAATGAGTACACCATCCGTCCCTTGGGAGTCACTGGAGTTGCAGGAGAACCC CTGCCAGTGGATAGTGAAAAAGACATCTTTGATTACATCCAGTGGAAATACCGGGAACCCAAGGACCGGAGCGAATGAGGCCTGTATCCTCCCTGGCAGA CACAACCCAATAGGAGTCTTAATTTATTTCTTAACCTTTGCTATGTAAGGGTCTTTGGTGTTTTTAAATGATTGTTTCTTCTTCATGCTTTTGCTTGCAA TGTAGTCAATAAAACCTCATGTACTATTATTGGATGAT

POLB.F7 (forward primer)
POLB.R13 (reverse primer)
Single exon skipping

Frame 0

NKRRAPRPPSGATIVPPVAPELGCSCSRLQVLV PPSSWERALVPGSEHSGVLGCRPP*ANGRRRRRL STGESPTCSQNSQTLRRT*AKLSTSTMLTEKQH LL*QNTHTK*RVELKLRNCLE*EQKLLKRLMSF *QLENYVNWKRFGRMIRVHPSIS*LELVALVHLL QGSL*MKELKH*KISEKMKIN*TIISELG*NIL GTLKKEFLVKRCYKCKILY*MKLKKWILNTLLQ SVAVSEEVQSPVVTWMFS*PIPASLQNQPNSQNC YIRLWSSYKRFILSQIPCQRVRQSSWVFASFPV KMMKKNIHTEELISG*YPKISITVVFSISLGVI FSIRI*GLMP*KRVSQSMSTPSVPWESLELQENP CQWIVKKTSLITSSGNTGNPRTGANEACILPGR HNPIGVLIYFLTFAM*GSLVFLNDCFFFMLLLA M*SIKPHVLLLDD

Frame 1

TSAVRPAPHRGQPLFRRSRRSWVAPAPVSKSWY LLQAGRGL*SLVLNTLGFSGAGRHEQTEGAAGD SQRGNHRHAHRTRKL*EEREPSYPQVQCLQKSSI CYSKIPTQNKEWS*S*EIAWSRNKNC*KD**VF SNWKIT*TGKDSAG*YEFIHQFPDSS*WHWSIC CKEVCR*RN*NTRRSQKK*R*IEPSSANWAEIFW GL*KKNSS*RDVTNARYCTK*S*KSGF*IHCYS LWQFQKRCRVQW*HGCSPDPSQLHFRINQTAKT VTSGCGAVTKGSFYHRYPVKG*DKVHGCLPASQ* K**KRISTQKN*YQVDTQRSVLLWCSLFHWE*Y FQ*EYEGSCPRKGFHNQ*VHHPSLGSHWSCRRT PASG**KRHL*LHPVEIPGTQGPERMRPVSSLAD TTQ*ES*FIS*PLLCKGLWCF*MIVSSSCFCLQ CSQ*NLMYYYWM

Frame 2

QAPCAPPPIGGNHCSAGRAGAGLLLLPSPSPGT SFKLGEGSSPWF*TLWGSRVQAAMSKRKAPQET LNGGITDMLTELANFEKNVSQAIHKYNAYRKAA SVIAKYPHKIKSGAEAKKLPGVGTKIAEKIDEFL ATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSA ARKFVDEGIKTLEDLRKNEDKLNHHQRIGLKYF GDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATV CGSFRRGAESSGDMDVLLTHPSFTSESTKQPKL LHQVVEQLQKVHFITDTLSKGETKFMGVCQLPS KNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDI FNKNMRAHALEKGFTINEYTIRPLGVTGVAGEP LPVDSEKDIFDYIQWKYREPKDRSE*GLYPPWQ TQPNRSLNLFLNLCYVRVFGVFK*LFLLHAFACN VVNKTSCTIIG*