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Sequences

Sequence FGFR3.bAug05

CGCGCGCTGCCTGAGGACGCCGCGGCCCCCGCCCCCGCCATGGGCGCCCCTGCCTGCGCCCTCGCGCTCTGCGTGGCCGTGGCCATCGTGGCCGGCGCCT
CCTCGGAGTCCTTGGGGACGGAGCAGCGCGTCGTGGGGCGAGCGGCAGAAGTCCCGGGCCCAGAGCCCGGCCAGCAGGAGCAGTTGGTCTTCGGCAGCGG
GGATGCTGTGGAGCTGAGCTGTCCCCCGCCCGGGGGTGGTCCCATGGGGCCCACTGTCTGGGTCAAGGATGGCACAGGGCTGGTGCCCTCGGAGCGTGTC
CTGGTGGGGCCCCAGCGGCTGCAGGTGCTGAATGCCTCCCACGAGGACTCCGGGGCCTACAGCTGCCGGCAGCGGCTCACGCAGCGCGTACTGTGCCACT
TCAGTGTGCGGGTGACAGACGCTCCATCCTCGGGAGATGACGAAGACGGGGAGGACGAGGCTGAGGACACAGGTGTGGACACAGGGGCCCCTTACTGGAC
ACGGCCCGAGCGGATGGACAAGAAGCTGCTGGCCGTGCCGGCCGCCAACACCGTCCGCTTCCGCTGCCCAGCCGCTGGCAACCCCACTCCCTCCATCTCC
TGGCTGAAGAACGGCAGGGAGTTCCGCGGCGAGCACCGCATTGGAGGCATCAAGCTGCGGCATCAGCAGTGGAGCCTGGTCATGGAAAGCGTGGTGCCCT
CGGACCGCGGCAACTACACCTGCGTCGTGGAGAACAAGTTTGGCAGCATCCGGCAGACGTACACGCTGGACGTGCTGGAGCGCTCCCCGCACCGGCCCAT
CCTGCAGGCGGGGCTGCCGGCCAACCAGACGGCGGTGCTGGGCAGCGACGTGGAGTTCCACTGCAAGGTGTACAGTGACGCACAGCCCCACATCCAGTGG
CTCAAGCACGTGGAGGTGAATGGCAGCAAGGTGGGCCCGGACGGCACACCCTACGTTACCGTGCTCAAGACGGCGGGCGCTAACACCACCGACAAGGAGC
TAGAGGTTCTCTCCTTGCACAACGTCACCTTTGAGGACGCCGGGGAGTACACCTGCCTGGCGGGCAATTCTATTGGGTTTTCTCATCACTCTGCGTGGCT
GGTGGTGCTGCCAGCCGAGGAGGAGCTGGTGGAGGCTGACGAGGCGGGCAGTGTGTATGCAGGCATCCTCAGCTACGGGGTGGGCTTCTTCCTGTTCATC
CTGGTGGTGGCGGCTGTGACGCTCTGCCGCCTGCGCAGCCCCCCCAAGAAAGGCCTGGGCTCCCCCACCGTGCACAAGATCTCCCGCTTCCCGCTCAAGC
GACAGGTGTCCCTGGAGTCCAACGCGTCCATGAGCTCCAACACACCACTGGTGCGCATCGCAAGGCTGTCCTCAGGGGAGGGCCCCACGCTGGCCAATGT
CTCCGAGCTCGAGCTGCCTGCCGACCCCAAATGGGAGCTGTCTCGGGCCCGGCTGACCCTGGGCAAGCCCCTTGGGGAGGGCTGCTTCGGCCAGGTGGTC
ATGGCGGAGGCCATCGGCATTGACAAGGACCGGGCCGCCAAGCCTGTCACCGTAGCCGTGAAGATGCTGAAAGACGATGCCACTGACAAGGACCTGTCGG
ACCTGGTGTCTGAGATGGAGATGATGAAGATGATCGGGAAACACAAAAACATCATCAACCTGCTGGGCGCCTGCACGCAGGGCGGGCCCCTGTACGTGCT
GGTGGAGTACGCGGCCAAGGGTAACCTGCGGGAGTTTCTGCGGGCGCGGCGGCCCCCGGGCCTGGACTACTCCTTCGACACCTGCAAGCCGCCCGAGGAG
CAGCTCACCTTCAAGGACCTGGTGTCCTGTGCCTACCAGGTGGCCCGGGGCATGGAGTACTTGGCCTCCCAGAAGTGCATCCACAGGGACCTGGCTGCCC
GCAATGTGCTGGTGACCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCGACTACTACAAGAAGACGACCAACGG
CCGGCTGCCCGTGAAGTGGATGGCGCCTGAGGCCTTGTTTGACCGAGTCTACACTCACCAGAGTGACGTCTGGTCCTTTGGGGTCCTGCTCTGGGAGATC
TTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGCTCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACAC
ACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTCCCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGT
GACGTCCACCGACGAGTACCTGGACCTGTCGGCGCCTTTCGAGCAGTACTCCCCGGGTGGCCAGGACACCCCCAGCTCCAGCTCCTCAGGGGACGACTCC
GTGTTTGCCCACGACCTGCTGCCCCCGGCCCCACCCAGCAGTGGGGGCTCGCGGACGTGAAGGGCCACTGGTCCCCAACAATGTGAGGGGTCCCTAGCAG
CCCACCCTGCTGCTGGTGCACAGCCACTCCCCGGCATGAGACTCAGTGCAGATGGAGAGACAGCTACACAGAGCTTTGGTCTGTGTGTGTGTGTGTGCGT
GTGTGTGTGTGTGTGTGCACATCCGCGTGTGCCTGTGTGCGTGCGCATCTTGCCTCCAGGTGCAGAGGTACCCTGGGTGTCCCCGCTGCTGTGCAACGGT
CTCCTGACTGGTGCTGCAGCACCGAGGGGCCTTTGTTCTGGGGGGACCCAGTGCAGAATGTAAGTGGGCCCACCCGGTGGGACCCCCGTGGGGCAGGGAG
CTGGGCCCGACATGGCTCCGGCCTCTGCCTTTGCACCACGGGACATCACAGGGTGGGCCTCGGCCCCTCCCACACCCAAAGCTGAGCCTGCAGGGAAGCC
CCACATGTCCAGCACCTTGTGCCTGGGGTGTTAGTGGCACCGCCTCCCCACCTCCAGGCTTTCCCACTTCCCACCCTGCCCCTCAGAGACTGAAATTACG
GGTACCTGAAGATGGGAGCCTTTACCTTTTATGCAAAAGGTTTATTCCGGAAACTAGTGTACATTTCTATAAATAGATGCTGTGTATATGGTATATATAC
ATATATATATATAACATATATGGAAGAGGAAAAGGCTGGTACAACGGAGGCCTGCGACCCTGGGGGCACAGGAGGCAGGCATGGCCCTGGGCGGGGCGTG
GGGGGGCGTGGAGGGAGGCCCCAGGGGGTCTCACCCATGCAAGCAGAGGACCAGGGCCTTTTCTGGCACCGCAGTTTTGTTTTAAAACTGGACCTGTATA
TTTGTAAAGCTATTTATGGGCCCCTGGCACTCTTGTTCCCACACCCCAACACTTCCAGCATTTAGCTGGCCACATGGCGGAGAGTTTTAATTTTTAACTT
ATTGACAACCGAGAAGGTTTATCCCGCCGATAGAGGGACGGCCAAGAATGTACGTCCAGCCTGCCCCGGAGCTGGAGGATCCCCTCCAAGCCTAAAAGGT
TGTTAATAGTTGGAGGTGATTCCAGTGAAGATATTTTATTTCCTTTGTCCTTTTTCAGGAGAATTAGATTTCTATAGGATTTTTCTTTAGGAGATTTATT
TTTTGGACTTCAAAGCAAGCTGGTATTTTCATACAAATTCTTCTAATTGCTGTGTGTCCCAGGCAGGGAGACGGTTTCCAGGGAGGGGCCGGCCCTGTGT
GCAGGTTCCGATGTTATTAGATGTTACAAGTTTATATATATCTATATATATAATTTATTGAGTTTTTACAAGATGTATTTGTTGTAGACTTAACACTTCT
TACGCAATGCTTCTAGAGTTTTATAGCCTGGACTGCTACCTTTCAAAGCTTGGAGGGAAGCCGTGAATTCAGTTGGTTCGTTCTGTACTGTTACTGGGCC
CTGAGTCTGGGCAGCTGTCCCTTGCTTGCCTGCAGGGCCATGGCTCAGGGTGGTCTCTTCTTGGGGCCCAGTGCATGGTGGCCAGAGGTGTCACCCAAAC
CGGCAGGTGCGATTTTGTTAACCCAGCGACGAACTTTCCGAAAAATAAAGACACCTGGTTGCTAACCTGG
  • FGFR3.F3 (forward primer)
  • FGFR3.R3 (reverse primer)
  • Alternative acceptor

Frame 0

RALPEDAAAPAPAMGAPACALALCVAVAIVAGA
SSESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSG
DAVELSCPPPGGGPMGPTVWVKDGTGLVPSERV
LVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCH
FSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWT
RPERMDKKLLAVPAANTVRFRCPAAGNPTPSIS
WLKNGREFRGEHRIGGIKLRHQQWSLVMESVVP
SDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPI
LQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQW
LKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKE
LEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWL
VVLPAEEELVEADEAGSVYAGILSYGVGFFLFI
LVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLK
RQVSLESNASMSSNTPLVRIARLSSGEGPTLANV
SELELPADPKWELSRARLTLGKPLGEGCFGQVV
MAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLS
DLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVL
VEYAAKGNLREFLRARRPPGLDYSFDTCKPPEE
QLTFKDLVSCAYQVARGMEYLASQKCIHRDLAA
RNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNG
RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEI
FTLGGSPYPGIPVEELFKLLKEGHRMDKPANCT
HDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTV
TSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDS
VFAHDLLPPAPPSSGGSRT*RATGPQQCEGSLA
AHPAAGAQPLPGMRLSADGETATQSFGLCVCVCV
CVCVCAHPRVPVCVRILPPGAEVPWVSPLLCNG
LLTGAAAPRGLCSGGTQCRM*VGPPGGTPVGQG
AGPDMAPASAFAPRDITGWASAPPTPKAEPAGKP
HMSSTLCLGC*WHRLPTSRLSHFPPCPSETEIT
GT*RWEPLPFMQKVYSGN*CTFL*IDAVYMVYI
HIYI*HIWKRKRLVQRRPATLGAQEAGMALGGAW
GGVEGGPRGSHPCKQRTRAFSGTAVLF*NWTCI
FVKLFMGPWHSCSHTPTLPAFSWPHGGEF*FLT
Y*QPRRFIPPIEGRPRMYVQPAPELEDPLQA*KV
VNSWR*FQ*RYFISFVLFQEN*ISIGFFFRRFI
FWTSKQAGIFIQILLIAVCPRQGDGFQGGAGPV
CRFRCY*MLQVYIYLYI*FIEFLQDVFVVDLTLL
TQCF*SFIAWTATFQSLEGSREFSWFVLYCYWA
LSLGSCPLLACRAMAQGGLFLGPSAWWPEVSPK
PAGAILLTQRRTFRKIKTPGC*P

Frame 1

ARCLRTPRPPPPPWAPLPAPSRSAWPWPSWPAP
PRSPWGRSSASWGERQKSRAQSPASRSSWSSAA
GMLWS*AVPRPGVVPWGPLSGSRMAQGWCPRSVS
WWGPSGCRC*MPPTRTPGPTAAGSGSRSAYCAT
SVCG*QTLHPREMTKTGRTRLRTQVWTQGPLTG
HGPSGWTRSCWPCRPPTPSASAAQPLATPLPPSP
G*RTAGSSAASTALEASSCGISSGAWSWKAWCP
RTAATTPASWRTSLAASGRRTRWTCWSAPRTGP
SCRRGCRPTRRRCWAATWSSTARCTVTHSPTSSG
SSTWR*MAARWARTAHPTLPCSRRRALTPPTRS
*RFSPCTTSPLRTPGSTPAWRAILLGFLITLRG
WWCCQPRRSWWRLTRRAVCMQASSATGWASSCSS
WWWRL*RSAACAAPPRKAWAPPPCTRSPASRSS
DRCPWSPTRP*APTHHWCASQGCPQGRAPRWPM
SPSSSCLPTPNGSCLGPG*PWASPLGRAASARWS
WRRPSALTRTGPPSLSP*P*RC*KTMPLTRTCR
TWCLRWR**R*SGNTKTSSTCWAPARRAGPCTC
WWSTRPRVTCGSFCGRGGPRAWTTPSTPASRPRS
SSPSRTWCPVPTRWPGAWSTWPPRSASTGTWLP
AMCW*PRTT**RSQTSGWPGTCTTSTTTRRRPT
AGCP*SGWRLRPCLTESTLTRVTSGPLGSCSGRS
SRWGAPRTPASLWRSSSSC*RRATAWTSPPTAH
TTCT*SCGSAGMPRPPRGPPSSSWWRTWTVSLP
*RPPTSTWTCRRLSSSTPRVARTPPAPAPQGTTP
CLPTTCCPRPHPAVGARGREGPLVPNNVRGP*Q
PTLLLVHSHSPA*DSVQMERQLHRALVCVCVCA
CVCVCVHIRVCLCACASCLQVQRYPGCPRCCATV
S*LVLQHRGAFVLGGPSAECKWAHPVGPPWGRE
LGPTWLRPLPLHHGTSQGGPRPLPHPKLSLQGS
PTCPAPCAWGVSGTASPPPGFPTSHPAPQRLKLR
VPEDGSLYLLCKRFIPETSVHFYK*MLCIWYIY
IYIYNIYGRGKGWYNGGLRPWGHRRQAWPWAGR
GGAWREAPGGLTHASRGPGPFLAPQFCFKTGPVY
L*SYLWAPGTLVPTPQHFQHLAGHMAESFNF*L
IDNREGLSRR*RDGQECTSSLPRSWRIPSKPKR
LLIVGGDSSEDILFPLSFFRRIRFL*DFSLGDLF
FGLQSKLVFSYKFF*LLCVPGRETVSREGPALC
AGSDVIRCYKFIYIYIYNLLSFYKMYLL*T*HF
LRNASRVL*PGLLPFKAWREAVNSVGSFCTVTGP
*VWAAVPCLPAGPWLRVVSSWGPVHGGQRCHPN
RQVRFC*PSDELSEK*RHLVANL

Frame 2

RAA*GRRGPRPRHGRPCLRPRALRGRGHRGRRL
LGVLGDGAARRGASGRSPGPRARPAGAVGLRQR
GCCGAELSPARGWSHGAHCLGQGWHRAGALGAC
PGGAPAAAGAECLPRGLRGLQLPAAAHAARTVPL
QCAGDRRSILGR*RRRGGRG*GHRCGHRGPLLD
TARADGQEAAGRAGRQHRPLPLPSRWQPHSLHL
LAEERQGVPRRAPHWRHQAAASAVEPGHGKRGAL
GPRQLHLRRGEQVWQHPADVHAGRAGALPAPAH
PAGGAAGQPDGGAGQRRGVPLQGVQ*RTAPHPV
AQARGGEWQQGGPGRHTLRYRAQDGGR*HHRQGA
RGSLLAQRHL*GRRGVHLPGGQFYWVFSSLCVA
GGAASRGGAGGG*RGGQCVCRHPQLRGGLLPVH
PGGGGCDALPPAQPPQERPGLPHRAQDLPLPAQA
TGVPGVQRVHELQHTTGAHRKAVLRGGPHAGQC
LRARAACRPQMGAVSGPADPGQAPWGGLLRPGG
HGGGHRH*QGPGRQACHRSREDAERRCH*QGPVG
PGV*DGDDEDDRETQKHHQPAGRLHAGRAPVRA
GGVRGQG*PAGVSAGAAAPGPGLLLRHLQAARG
AAHLQGPGVLCLPGGPGHGVLGLPEVHPQGPGCP
QCAGDRGQRDEDRRLRAGPGRAQPRLLQEDDQR
PAAREVDGA*GLV*PSLHSPE*RLVLWGPALGD
LHAGGLPVPRHPCGGALQAAEGGPPHGQARQLHT
RPVHDHAGVLACRALPEAHLQAAGGGPGPCPYR
DVHRRVPGPVGAFRAVLPGWPGHPQLQLLRGRL
RVCPRPAAPGPTQQWGLADVKGHWSPTM*GVPSS
PPCCWCTATPRHETQCRWRDSYTELWSVCVCVR
VCVCVCTSACACVRAHLASRCRGTLGVPAAVQR
SPDWCCSTEGPLFWGDPVQNVSGPTRWDPRGAGS
WARHGSGLCLCTTGHHRVGLGPSHTQS*ACREA
PHVQHLVPGVLVAPPPHLQAFPLPTLPLRD*NY
GYLKMGAFTFYAKGLFRKLVYISINRCCVYGIYT
YIYITYMEEEKAGTTEACDPGGTGGRHGPGRGV
GGRGGRPQGVSPMQAEDQGLFWHRSFVLKLDLY
ICKAIYGPLALLFPHPNTSSI*LATWRRVLIFNL
LTTEKVYPADRGTAKNVRPACPGAGGSPPSLKG
C**LEVIPVKIFYFLCPFSGELDFYRIFL*EIY
FLDFKASWYFHTNSSNCCVSQAGRRFPGRGRPCV
QVPMLLDVTSLYISIYIIY*VFTRCICCRLNTS
YAMLLEFYSLDCYLSKLGGKP*IQLVRSVLLLG
PESGQLSLACLQGHGSGWSLLGAQCMVARGVTQT
GRCDFVNPATNFPKNKDTWLLTW

Sequence FGFR3.aAug05

GCGGCGTCGCGGGCAGCTGGCGCCGCGCGGTCCTGCTCTGCCGGTCGCACGGACGCACCGGCGGGCCGCCGGCCGGAGGGACGGGGCGGGAGCTGGGCCC
GCGGACAGCGAGCCGGAGCGGGAGCCGCGCGTAGCGAGCCGGGCTCCGGCGCTCGCCAGTCTCCCGAGCGGCGCCCGCCTCCCGCCGGTGCCCGCGCCGG
GCCGTGGGGGGCAGCATGCCCGCGCGCGCTGCCTGAGGACGCCGCGGCCCCCGCCCCCGCCATGGGCGCCCCTGCCTGCGCCCTCGCGCTCTGCGTGGCC
GTGGCCATCGTGGCCGGCGCCTCCTCGGAGTCCTTGGGGACGGAGCAGCGCGTCGTGGGGCGAGCGGCAGAAGTCCCGGGCCCAGAGCCCGGCCAGCAGG
AGCAGTTGGTCTTCGGCAGCGGGGATGCTGTGGAGCTGAGCTGTCCCCCGCCCGGGGGTGGTCCCATGGGGCCCACTGTCTGGGTCAAGGATGGCACAGG
GCTGGTGCCCTCGGAGCGTGTCCTGGTGGGGCCCCAGCGGCTGCAGGTGCTGAATGCCTCCCACGAGGACTCCGGGGCCTACAGCTGCCGGCAGCGGCTC
ACGCAGCGCGTACTGTGCCACTTCAGTGTGCGGGTGACAGACGCTCCATCCTCGGGAGATGACGAAGACGGGGAGGACGAGGCTGAGGACACAGGTGTGG
ACACAGGGGCCCCTTACTGGACACGGCCCGAGCGGATGGACAAGAAGCTGCTGGCCGTGCCGGCCGCCAACACCGTCCGCTTCCGCTGCCCAGCCGCTGG
CAACCCCACTCCCTCCATCTCCTGGCTGAAGAACGGCAGGGAGTTCCGCGGCGAGCACCGCATTGGAGGCATCAAGCTGCGGCATCAGCAGTGGAGCCTG
GTCATGGAAAGCGTGGTGCCCTCGGACCGCGGCAACTACACCTGCGTCGTGGAGAACAAGTTTGGCAGCATCCGGCAGACGTACACGCTGGACGTGCTGG
AGCGCTCCCCGCACCGGCCCATCCTGCAGGCGGGGCTGCCGGCCAACCAGACGGCGGTGCTGGGCAGCGACGTGGAGTTCCACTGCAAGGTGTACAGTGA
CGCACAGCCCCACATCCAGTGGCTCAAGCACGTGGAGGTGAATGGCAGCAAGGTGGGCCCGGACGGCACACCCTACGTTACCGTGCTCAAGACGGCGGGC
GCTAACACCACCGACAAGGAGCTAGAGGTTCTCTCCTTGCACAACGTCACCTTTGAGGACGCCGGGGAGTACACCTGCCTGGCGGGCAATTCTATTGGGT
TTTCTCATCACTCTGCGTGGCTGGTGGTGCTGCCAGCCGAGGAGGAGCTGGTGGAGGCTGACGAGGCGGGCAGTGTGTATGCAGGCATCCTCAGCTACGG
GGTGGGCTTCTTCCTGTTCATCCTGGTGGTGGCGGCTGTGACGCTCTGCCGCCTGCGCAGCCCCCCCAAGAAAGGCCTGGGCTCCCCCACCGTGCACAAG
ATCTCCCGCTTCCCGCTCAAGCGACAGCAGGTGTCCCTGGAGTCCAACGCGTCCATGAGCTCCAACACACCACTGGTGCGCATCGCAAGGCTGTCCTCAG
GGGAGGGCCCCACGCTGGCCAATGTCTCCGAGCTCGAGCTGCCTGCCGACCCCAAATGGGAGCTGTCTCGGGCCCGGCTGACCCTGGGCAAGCCCCTTGG
GGAGGGCTGCTTCGGCCAGGTGGTCATGGCGGAGGCCATCGGCATTGACAAGGACCGGGCCGCCAAGCCTGTCACCGTAGCCGTGAAGATGCTGAAAGAC
GATGCCACTGACAAGGACCTGTCGGACCTGGTGTCTGAGATGGAGATGATGAAGATGATCGGGAAACACAAAAACATCATCAACCTGCTGGGCGCCTGCA
CGCAGGGCGGGCCCCTGTACGTGCTGGTGGAGTACGCGGCCAAGGGTAACCTGCGGGAGTTTCTGCGGGCGCGGCGGCCCCCGGGCCTGGACTACTCCTT
CGACACCTGCAAGCCGCCCGAGGAGCAGCTCACCTTCAAGGACCTGGTGTCCTGTGCCTACCAGGTGGCCCGGGGCATGGAGTACTTGGCCTCCCAGAAG
TGCATCCACAGGGACCTGGCTGCCCGCAATGTGCTGGTGACCGAGGACAACGTGATGAAGATCGCAGACTTCGGGCTGGCCCGGGACGTGCACAACCTCG
ACTACTACAAGAAGACGACCAACCTGGTCCTTTGGGGTCCTGCTCTGGGAGATCTTCACGCTGGGGGGCTCCCCGTACCCCGGCATCCCTGTGGAGGAGC
TCTTCAAGCTGCTGAAGGAGGGCCACCGCATGGACAAGCCCGCCAACTGCACACACGACCTGTACATGATCATGCGGGAGTGCTGGCATGCCGCGCCCTC
CCAGAGGCCCACCTTCAAGCAGCTGGTGGAGGACCTGGACCGTGTCCTTACCGTGACGTCCACCGACGAGTACCTGGACCTGTCGGCGCCTTTCGAGCAG
TACTCCCCGGGTGGCCAGGACACCCCCAGCTCCAGCTCCTCAGGGGACGACTCCGTGTTTGCCCACGACCTGCTGCCCCCGGCCCCACCCAGCAGTGGGG
GCTCGCGGACGTGAAGGGCCACTGGTCCCCAACAATGTGAGGGGTCCCTAGCAGCCCACCCTGCTGCTGGTGCACAGCCACTCCCCGGCATGAGACTCAG
TGCAGATGGAGAGACAGCTACACAGAGCTTTGGTCTGTGTGTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGCACATCCGCGTGTGCCTGTGTGCGTGCGC
ATCTTGCCTCCAGGTGCAGAGGTACCCTGGGTGTCCCCGCTGCTGTGCAACGGTCTCCTGACTGGTGCTGCAGCACCGAGGGGCCTTTGTTCTGGGGGGA
CCCAGTGCAGAATGTAAGTGGGCCCACCCGGTGGGACCCCCGTGGGGCAGGGAGCTGGGCCCGACATGGCTCCGGCCTCTGCCTTTGCACCACGGGACAT
CACAGGGTGGGCCTCGGCCCCTCCCACACCCAAAGCTGAGCCTGCAGGGAAGCCCCACATGTCCAGCACCTTGTGCCTGGGGTGTTAGTGGCACCGCCTC
CCCACCTCCAGGCTTTCCCACTTCCCACCCTGCCCCTCAGAGACTGAAATTACGGGTACCTGAAGATGGGAGCCTTTACCTTTTATGCAAAAGGTTTATT
CCGGAAACTAGTGTACATTTCTATAAATAGATGCTGTGTATATGGTATATATACATATATATATATAACATATATGGAAGAGGAAAAGGCTGGTACAACG
GAGGCCTGCGACCCTGGGGGCACAGGAGGCAGGCATGGCCCTGGGCGGGGCGTGGGGGGGCGTGGAGGGAGGCCCCAGGGGGTCTCACCCATGCAAGCAG
AGGACCAGGGCCTTTTCTGGCACCGCAGTTTTGTTTTAAAACTGGACCTGTATATTTGTAAAGCTATTTATGGGCCCCTGGCACTCTTGTTCCCACACCC
CAACACTTCCAGCATTTAGCTGGCCACATGGCGGAGAGTTTTAATTTTTAACTTATTGACAACCGAGAAGGTTTATCCCGCCGATAGAGGGACGGCCAAG
AATGTACGTCCAGCCTGCCCCGGAGCTGGAGGATCCCCTCCAAGCCTAAAAGGTTGTTAATAGTTGGAGGTGATTCCAGTGAAGATATTTTATTTCCTTT
GTCCTTTTTCAGGAGAATTAGATTTCTATAGGATTTTTCTTTAGGAGATTTATTTTTTGGACTTCAAAGCAAGCTGGTATTTTCATACAAATTCTTCTAA
TTGCTGTGTGTCCCAGGCAGGGAGACGGTTTCCAGGGAGGGGCCGGCCCTGTGTGCAGGTTCCGATGTTATTAGATGTTACAAGTTTATATATATCTATA
TATATAATTTATTGAGTTTTTACAAGATGTATTTGTTGTAGACTTAACACTTCTTACGCAATGCTTCTAGAGTTTTATAGCCTGGACTGCTACCTTTCAA
AGCTTGGAGGGAAGCCGTGAATTCAGTTGGTTCGTTCTGTACTGTTACTGGGCCCTGAGTCTGGGCAGCTGTCCCTTGCTTGCCTGCAGGGCCATGGCTC
AGGGTGGTCTCTTCTTGGGGCCCAGTGCATGGTGGCCAGAGGTGTCACCCAAACCGGCAGGTGCGATTTTGTTAACCCAGCGACGAACTTTCCGAAAAAT
AAAGACACCTGGTTGCTAACCTGG
  • FGFR3.F3 (forward primer)
  • FGFR3.R3 (reverse primer)
  • Alternative acceptor

Frame 0

AASRAAGAARSCSAGRTDAPAGRRPEGRGGSWA
RGQRAGAGAARSEPGSGARQSPERRPPPAGARAG
PWGAACPRALPEDAAAPAPAMGAPACALALCVA
VAIVAGASSESLGTEQRVVGRAAEVPGPEPGQQ
EQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTG
LVPSERVLVGPQRLQVLNASHEDSGAYSCRQRL
TQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGV
DTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAG
NPTPSISWLKNGREFRGEHRIGGIKLRHQQWSL
VMESVVPSDRGNYTCVVENKFGSIRQTYTLDVL
ERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSD
AQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAG
ANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIG
FSHHSAWLVVLPAEEELVEADEAGSVYAGILSYG
VGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHK
ISRFPLKRQQVSLESNASMSSNTPLVRIARLSS
GEGPTLANVSELELPADPKWELSRARLTLGKPLG
EGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKD
DATDKDLSDLVSEMEMMKMIGKHKNIINLLGAC
TQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSF
DTCKPPEEQLTFKDLVSCAYQVARGMEYLASQK
CIHRDLAARNVLVTEDNVMKIADFGLARDVHNL
DYYKKTTNLVLWGPALGDLHAGGLPVPRHPCGGA
LQAAEGGPPHGQARQLHTRPVHDHAGVLACRAL
PEAHLQAAGGGPGPCPYRDVHRRVPGPVGAFRA
VLPGWPGHPQLQLLRGRLRVCPRPAAPGPTQQWG
LADVKGHWSPTM*GVPSSPPCCWCTATPRHETQ
CRWRDSYTELWSVCVCVRVCVCVCTSACACVRA
HLASRCRGTLGVPAAVQRSPDWCCSTEGPLFWGD
PVQNVSGPTRWDPRGAGSWARHGSGLCLCTTGH
HRVGLGPSHTQS*ACREAPHVQHLVPGVLVAPP
PHLQAFPLPTLPLRD*NYGYLKMGAFTFYAKGLF
RKLVYISINRCCVYGIYTYIYITYMEEEKAGTT
EACDPGGTGGRHGPGRGVGGRGGRPQGVSPMQA
EDQGLFWHRSFVLKLDLYICKAIYGPLALLFPHP
NTSSI*LATWRRVLIFNLLTTEKVYPADRGTAK
NVRPACPGAGGSPPSLKGC**LEVIPVKIFYFL
CPFSGELDFYRIFL*EIYFLDFKASWYFHTNSSN
CCVSQAGRRFPGRGRPCVQVPMLLDVTSLYISI
YIIY*VFTRCICCRLNTSYAMLLEFYSLDCYLS
KLGGKP*IQLVRSVLLLGPESGQLSLACLQGHGS
GWSLLGAQCMVARGVTQTGRCDFVNPATNFPKN
KDTWLLTW

Frame 1

RRRGQLAPRGPALPVARTHRRAAGRRDGAGAGP
ADSEPEREPRVASRAPALASLPSGARLPPVPAP
GRGGQHARARCLRTPRPPPPPWAPLPAPSRSAWP
WPSWPAPPRSPWGRSSASWGERQKSRAQSPASR
SSWSSAAGMLWS*AVPRPGVVPWGPLSGSRMAQ
GWCPRSVSWWGPSGCRC*MPPTRTPGPTAAGSGS
RSAYCATSVCG*QTLHPREMTKTGRTRLRTQVW
TQGPLTGHGPSGWTRSCWPCRPPTPSASAAQPL
ATPLPPSPG*RTAGSSAASTALEASSCGISSGAW
SWKAWCPRTAATTPASWRTSLAASGRRTRWTCW
SAPRTGPSCRRGCRPTRRRCWAATWSSTARCTV
THSPTSSGSSTWR*MAARWARTAHPTLPCSRRRA
LTPPTRS*RFSPCTTSPLRTPGSTPAWRAILLG
FLITLRGWWCCQPRRSWWRLTRRAVCMQASSAT
GWASSCSSWWWRL*RSAACAAPPRKAWAPPPCTR
SPASRSSDSRCPWSPTRP*APTHHWCASQGCPQ
GRAPRWPMSPSSSCLPTPNGSCLGPG*PWASPL
GRAASARWSWRRPSALTRTGPPSLSP*P*RC*KT
MPLTRTCRTWCLRWR**R*SGNTKTSSTCWAPA
RRAGPCTCWWSTRPRVTCGSFCGRGGPRAWTTP
STPASRPRSSSPSRTWCPVPTRWPGAWSTWPPRS
ASTGTWLPAMCW*PRTT**RSQTSGWPGTCTTS
TTTRRRPTWSFGVLLWEIFTLGGSPYPGIPVEE
LFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPS
QRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQ
YSPGGQDTPSSSSSGDDSVFAHDLLPPAPPSSG
GSRT*RATGPQQCEGSLAAHPAAGAQPLPGMRLS
ADGETATQSFGLCVCVCVCVCVCAHPRVPVCVR
ILPPGAEVPWVSPLLCNGLLTGAAAPRGLCSGG
TQCRM*VGPPGGTPVGQGAGPDMAPASAFAPRDI
TGWASAPPTPKAEPAGKPHMSSTLCLGC*WHRL
PTSRLSHFPPCPSETEITGT*RWEPLPFMQKVY
SGN*CTFL*IDAVYMVYIHIYI*HIWKRKRLVQR
RPATLGAQEAGMALGGAWGGVEGGPRGSHPCKQ
RTRAFSGTAVLF*NWTCIFVKLFMGPWHSCSHT
PTLPAFSWPHGGEF*FLTY*QPRRFIPPIEGRPR
MYVQPAPELEDPLQA*KVVNSWR*FQ*RYFISF
VLFQEN*ISIGFFFRRFIFWTSKQAGIFIQILL
IAVCPRQGDGFQGGAGPVCRFRCY*MLQVYIYLY
I*FIEFLQDVFVVDLTLLTQCF*SFIAWTATFQ
SLEGSREFSWFVLYCYWALSLGSCPLLACRAMA
QGGLFLGPSAWWPEVSPKPAGAILLTQRRTFRKI
KTPGC*P

Frame 2

GVAGSWRRAVLLCRSHGRTGGPPAGGTGRELGP
RTASRSGSRA*RAGLRRSPVSRAAPASRRCPRR
AVGGSMPARAA*GRRGPRPRHGRPCLRPRALRG
RGHRGRRLLGVLGDGAARRGASGRSPGPRARPAG
AVGLRQRGCCGAELSPARGWSHGAHCLGQGWHR
AGALGACPGGAPAAAGAECLPRGLRGLQLPAAA
HAARTVPLQCAGDRRSILGR*RRRGGRG*GHRCG
HRGPLLDTARADGQEAAGRAGRQHRPLPLPSRW
QPHSLHLLAEERQGVPRRAPHWRHQAAASAVEP
GHGKRGALGPRQLHLRRGEQVWQHPADVHAGRAG
ALPAPAHPAGGAAGQPDGGAGQRRGVPLQGVQ*
RTAPHPVAQARGGEWQQGGPGRHTLRYRAQDGG
R*HHRQGARGSLLAQRHL*GRRGVHLPGGQFYWV
FSSLCVAGGAASRGGAGGG*RGGQCVCRHPQLR
GGLLPVHPGGGGCDALPPAQPPQERPGLPHRAQ
DLPLPAQATAGVPGVQRVHELQHTTGAHRKAVLR
GGPHAGQCLRARAACRPQMGAVSGPADPGQAPW
GGLLRPGGHGGGHRH*QGPGRQACHRSREDAER
RCH*QGPVGPGV*DGDDEDDRETQKHHQPAGRLH
AGRAPVRAGGVRGQG*PAGVSAGAAAPGPGLLL
RHLQAARGAAHLQGPGVLCLPGGPGHGVLGLPE
VHPQGPGCPQCAGDRGQRDEDRRLRAGPGRAQPR
LLQEDDQPGPLGSCSGRSSRWGAPRTPASLWRS
SSSC*RRATAWTSPPTAHTTCT*SCGSAGMPRP
PRGPPSSSWWRTWTVSLP*RPPTSTWTCRRLSSS
TPRVARTPPAPAPQGTTPCLPTTCCPRPHPAVG
ARGREGPLVPNNVRGP*QPTLLLVHSHSPA*DS
VQMERQLHRALVCVCVCACVCVCVHIRVCLCACA
SCLQVQRYPGCPRCCATVS*LVLQHRGAFVLGG
PSAECKWAHPVGPPWGRELGPTWLRPLPLHHGT
SQGGPRPLPHPKLSLQGSPTCPAPCAWGVSGTAS
PPPGFPTSHPAPQRLKLRVPEDGSLYLLCKRFI
PETSVHFYK*MLCIWYIYIYIYNIYGRGKGWYN
GGLRPWGHRRQAWPWAGRGGAWREAPGGLTHASR
GPGPFLAPQFCFKTGPVYL*SYLWAPGTLVPTP
QHFQHLAGHMAESFNF*LIDNREGLSRR*RDGQ
ECTSSLPRSWRIPSKPKRLLIVGGDSSEDILFPL
SFFRRIRFL*DFSLGDLFFGLQSKLVFSYKFF*
LLCVPGRETVSREGPALCAGSDVIRCYKFIYIY
IYNLLSFYKMYLL*T*HFLRNASRVL*PGLLPFK
AWREAVNSVGSFCTVTGP*VWAAVPCLPAGPWL
RVVSSWGPVHGGQRCHPNRQVRFC*PSDELSEK
*RHLVANL

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