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Sequences

Sequence FGFR4.cAug05

CGGGGTGGGACAGGAGGTGGGCCGCTCGCGGCCACGCCGCCGTCGCGGGTACATTCCTCGCTCCCGGCCGAGGAGCGCTCGGGCTGTCTGCGGACCCTGC CGCGTGCAGGGGTCGCGGCCGGCTGGAGCTGGGAGTGAGGCGGCGGAGGAGCCAGGAAGGCAGTTGGTGGGAAGTCCAGCTTGGGTCCCTGAGAGCTGTG AGAAGGAGATGCGGCTGCTGCTGGCCCTGTTGGGGGTCCTGCTGAGTGTGCCTGGGCCTCCAGTCTTGTCCCTGGAGGCCTCTGAGGAAGTGGAGCTTGA GCCCTGCCTGGCTCCCAGCCTGGAGCAGCAAGAGCAGGAGCTGACAGTAGCCCTTGGGCAGCCTGTGCGTCTGTGCTGTGGGCGGGCTGAGCGTGGTGGC CACTGGTACAAGGAGGGCAGTCGCCTGGCACCTGCTGGCCGTGTACGGGGCTGGAGGGGCCGCCTAGAGATTGCCAGCTTCCTACCTGAGGATGCTGGCC GCTACCTCTGCCTGGCACGAGGCTCCATGATCGTCCTGCAGAATCTCACCTTGATTACAGGTGACTCCTTGACCTCCAGCAACGATGATGAGGACCCCAA GTCCCATAGGGACCCCTCGAATAGGCACAGTTACCCCCAGCAAGCACCCTACTGGACACACCCCCAGCGCATGGAGAAGAAACTGCATGCAGTACCTGCG GGGAACACCGTCAAGTTCCGCTGTCCAGCTGCAGGCAACCCCACGCCCACCATCCGCTGGCTTAAGGATGGACAGGCCTTTCATGGGGAGAACCGCATTG GAGGCATTCGGCTGCGCCATCAGCACTGGAGTCTCGTGATGGAGAGCGTGGTGCCCTCGGACCGCGGCACATACACCTGCCTGGTAGAGAACGCTGTGGG CAGCATCCGCTATAACTACCTGCTAGATGTGCTGGAGCGGTCCCCGCACCGGCCCATCCTGCAGGCCGGGCTCCCGGCCAACACCACAGCCGTGGTGGGC AGCGACGTGGAGCTGCTGTGCAAGGTGTACAGCGATGCCCAGCCCCACATCCAGTGGCTGAAGCACATCGTCATCAACGGCAGCAGCTTCGGAGCCGACG GTTTCCCCTATGTGCAAGTCCTAAAGACTGCAGACATCAATAGCTCAGAGGTGGAGGTCCTGTACCTGCGGAACGTGTCAGCCGAGGACGCAGGCGAGTA CACCTGCCTCGCAGGCAATTCCATCGGCCTCTCCTACCAGTCTGCCTGGCTCACGGTGCTGCCAGGTACTGGGCGCATCCCCCACCTCACATGTGACAGC CTGACTCCAGCAGGCAGAACCAAGTCTCCCACTTTGCAGTTCTCCCTGGAGTCAGGCTCTTCCGGCAAGTCAAGCTCATCCCTGGTACGAGGCGTGCGTC TCTCCTCCAGCGGCCCCGCCTTGCTCGCCGGCCTCGTGAGTCTAGATCTACCTCTCGACCCACTATGGGAGTTCCCCCGGGACAGGCTGGTGCTTGGGAA GCCCCTAGGCGAGGGCTGCTTTGGCCAGGTAGTACGTGCAGAGGCCTTTGGCATGGACCCTGCCCGGCCTGACCAAGCCAGCACTGTGGCCGTCAAGATG CTCAAAGACAACGCCTCTGACAAGGACCTGGCCGACCTGGTCTCGGAGATGGAGGTGATGAAGCTGATCGGCCGACACAAGAACATCATCAACCTGCTTG GTGTCTGCACCCAGGAAGGGCCCCTGTACGTGATCGTGGAGTGCGCCGCCAAGGGAAACCTGCGGGAGTTCCTGCGGGCCCGGCGCCCCCCAGGCCCCGA CCTCAGCCCCGACGGTCCTCGGAGCAGTGAGGGGCCGCTCTCCTTCCCAGTCCTGGTCTCCTGCGCCTACCAGGTGGCCCGAGGCATGCAGTATCTGGAG TCCCGGAAGTGTATCCACCGGGACCTGGCTGCCCGCAATGTGCTGGTGACTGAGGACAATGTGATGAAGATTGCTGACTTTGGGCTGGCCCGCGGCGTCC ACCACATTGACTACTATAAGAAAACCAGCAACGGCCGCCTGCCTGTGAAGTGGATGGCGCCCGAGGCCTTGTTTGACCGGGTGTACACACACCAGAGTGA CGTGTGGTCTTTTGGGATCCTGCTATGGGAGATCTTCACCCTCGGGGGCTCCCCGTATCCTGGCATCCCGGTGGAGGAGCTGTTCTCGCTGCTGCGGGAG GGACATCGGATGGACCGACCCCCACACTGCCCCCCAGAGCTGTACGGGCTGATGCGTGAGTGCTGGCACGCAGCGCCCTCCCAGAGGCCTACCTTCAAGC AGCTGGTGGAGGCGCTGGACAAGGTCCTGCTGGCCGTCTCTGAGGAGTACCTCGACCTCCGCCTGACCTTCGGACCCTATTCCCCCTCTGGTGGGGACGC CAGCAGCACCTGCTCCTCCAGCGATTCTGTCTTCAGCCACGACCCCCTGCCATTGGGATCCAGCTCCTTCCCCTTCGGGTCTGGGGTGCAGACATGAGCA AGGCTCAAGGCTGTGCAGGCACATAGGCTGGTGGCCTTGGGCCTTGGGGCTCAGCCACAGCCTGACACAGTGCTCGACCTTGATAGCATGGGGCCCCTGG CCCAGAGTTGCTGTGCCGTGTCCAAGGGCCGTGCCCTTGCCCTTGGAGCTGCCGTGCCTGTGTCCTGATGGCCCAAATGTCAGGGTTCTGCTCGGCTTCT TGGACCTTGGCGCTTAGTCCCCATCCCGGGTTTGGCTGAGCCTGGCTGGAGAGCTGCTATGCTAAACCTCCTGCCTCCCAATACCAGCAGGAGGTTCTGG GCCTCTGAACCCCCTTTCCCCACACCTCCCCCTGCTGCTGCTGCCCCAGCGTCTTGACGGGAGCATTGGCCCCTGAGCCCAGAGAAGCTGGAAGCCTGCC GAAAACAGGAGCAAATGGCGTTTTATAAATTATTTTTTTGAAATAAAGCTCTGTGTGCCTGGGTC

FGFR4.F7 (forward primer)
FGFR4.R1 (reverse primer)
Alternative donor

Frame 0

RGGTGGGPLAATPPSRVHSSLPAEERSGCLRTL PRAGVAAGWSWE*GGGGARKAVGGKSSLGP*EL* EGDAAAAGPVGGPAECAWASSLVPGGL*GSGA* ALPGSQPGAARAGADSSPWAACASVLWAG*AWW PLVQGGQSPGTCWPCTGLEGPPRDCQLPT*GCWP LPLPGTRLHDRPAESHLDYR*LLDLQQR**GPQ VP*GPLE*AQLPPASTLLDTPPAHGEETACSTC GEHRQVPLSSCRQPHAHHPLA*GWTGLSWGEPHW RHSAAPSALESRDGERGALGPRHIHLPGRERCG QHPL*LPARCAGAVPAPAHPAGRAPGQHHSRGG QRRGAAVQGVQRCPAPHPVAEAHRHQRQQLRSRR FPLCASPKDCRHQ*LRGGGPVPAERVSRGRRRV HLPRRQFHRPLLPVCLAHGAARYWAHPPPHM*Q PDSSRQNQVSHFAVLPGVRLFRQVKLIPGTRRAS LLQRPRLARRPRESRSTSRPTMGVPPGQAGAWE APRRGLLWPGSTCRGLWHGPCPA*PSQHCGRQD AQRQRL*QGPGRPGLGDGGDEADRPTQEHHQPAW CLHPGRAPVRDRGVRRQGKPAGVPAGPAPPRPR PQPRRSSEQ*GAALLPSPGLLRLPGGPRHAVSG VPEVYPPGPGCPQCAGD*GQCDEDC*LWAGPRRP PH*LL*ENQQRPPACEVDGARGLV*PGVHTPE* RVVFWDPAMGDLHPRGLPVSWHPGGGAVLAAAG GTSDGPTPTLPPRAVRADA*VLARSALPEAYLQA AGGGAGQGPAGRL*GVPRPPPDLRTLFPLWWGR QQHLLLQRFCLQPRPPAIGIQLLPLRVWGADMS KAQGCAGT*AGGLGPWGSATA*HSARP**HGAPG PELLCRVQGPCPCPWSCRACVLMAQMSGFCSAS WTLALSPHPGFG*AWLESCYAKPPASQYQQEVL GL*TPFPHTSPCCCCPSVLTGALAPEPREAGSLP KTGANGVL*IIFLK*SSVCLG

Frame 1

GVGQEVGRSRPRRRRGYIPRSRPRSARAVCGPC RVQGSRPAGAGSEAAEEPGRQLVGSPAWVPESC EKEMRLLLALLGVLLSVPGPPVLSLEASEEVELE PCLAPSLEQQEQELTVALGQPVRLCCGRAERGG HWYKEGSRLAPAGRVRGWRGRLEIASFLPEDAG RYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPK SHRDPSNRHSYPQQAPYWTHPQRMEKKLHAVPA GNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRI GGIRLRHQHWSLVMESVVPSDRGTYTCLVENAVG SIRYNYLLDVLERSPHRPILQAGLPANTTAVVG SDVELLCKVYSDAQPHIQWLKHIVINGSSFGAD GFPYVQVLKTADINSSEVEVLYLRNVSAEDAGEY TCLAGNSIGLSYQSAWLTVLPGTGRIPHLTCDS LTPAGRTKSPTLQFSLESGSSGKSSSSLVRGVR LSSSGPALLAGLVSLDLPLDPLWEFPRDRLVLGK PLGEGCFGQVVRAEAFGMDPARPDQASTVAVKM LKDNASDKDLADLVSEMEVMKLIGRHKNIINLL GVCTQEGPLYVIVECAAKGNLREFLRARRPPGPD LSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLE SRKCIHRDLAARNVLVTEDNVMKIADFGLARGV HHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSD VWSFGILLWEIFTLGGSPYPGIPVEELFSLLRE GHRMDRPPHCPPELYGLMRECWHAAPSQRPTFK QLVEALDKVLLAVSEEYLDLRLTFGPYSPSGGDA SSTCSSSDSVFSHDPLPLGSSSFPFGSGVQT*A RLKAVQAHRLVALGLGAQPQPDTVLDLDSMGPL AQSCCAVSKGRALALGAAVPVS*WPKCQGSARLL GPWRLVPIPGLAEPGWRAAMLNLLPPNTSRRFW ASEPPFPTPPPAAAAPAS*REHWPLSPEKLEAC RKQEQMAFYKLFF*NKALCAWV

Frame 2

GWDRRWAARGHAAVAGTFLAPGRGALGLSADPA ACRGRGRLELGVRRRRSQEGSWWEVQLGSLRAV RRRCGCCWPCWGSC*VCLGLQSCPWRPLRKWSL SPAWLPAWSSKSRS*Q*PLGSLCVCAVGGLSVVA TGTRRAVAWHLLAVYGAGGAA*RLPASYLRMLA ATSAWHEAP*SSCRISP*LQVTP*PPATMMRTP SPIGTPRIGTVTPSKHPTGHTPSAWRRNCMQYLR GTPSSSAVQLQATPRPPSAGLRMDRPFMGRTAL EAFGCAISTGVS*WRAWCPRTAAHTPAW*RTLW AASAITTC*MCWSGPRTGPSCRPGSRPTPQPWWA ATWSCCARCTAMPSPTSSG*STSSSTAAASEPT VSPMCKS*RLQTSIAQRWRSCTCGTCQPRTQAS TPASQAIPSASPTSLPGSRCCQVLGASPTSHVTA *LQQAEPSLPLCSSPWSQALPASQAHPWYEACV SPPAAPPCSPAS*V*IYLSTHYGSSPGTGWCLG SP*ARAALAR*YVQRPLAWTLPGLTKPALWPSRC SKTTPLTRTWPTWSRRWR**S*SADTRTSSTCL VSAPRKGPCT*SWSAPPRETCGSSCGPGAPQAP TSAPTVLGAVRGRSPSQSWSPAPTRWPEACSIWS PGSVSTGTWLPAMCW*LRTM**RLLTLGWPAAS TTLTTIRKPATAACL*SGWRPRPCLTGCTHTRV TCGLLGSCYGRSSPSGAPRILASRWRSCSRCCGR DIGWTDPHTAPQSCTG*CVSAGTQRPPRGLPSS SWWRRWTRSCWPSLRSTSTSA*PSDPIPPLVGT PAAPAPPAILSSATTPCHWDPAPSPSGLGCRHEQ GSRLCRHIGWWPWALGLSHSLTQCSTLIAWGPW PRVAVPCPRAVPLPLELPCLCPDGPNVRVLLGF LDLGA*SPSRVWLSLAGELLC*TSCLPIPAGGSG PLNPLSPHLPLLLLPQRLDGSIGP*AQRSWKPA ENRSKWRFINYFFEIKLCVPG

Sequence FGFR4.gAug05

FGFR4.F7 (forward primer)
FGFR4.R1 (reverse primer)
Alternative donor

Frame 0

RSRPRRRRGYIPRSRPRSARAVCGPCRVQGSRP AGAGSEAAEEPGEEEPGEQDPVLGAESRRLEEGS WWEVQLGSLRAVRRRCGCCWPCWGSC*VCLGLQ SCPWRPLRKWSLVVRDSSRE*RDAWGDRPAPLG P*MLPSVPDVDSLTSSNDDEDPKSHRDPSNRHSY PQQAPYWTHPQRMEKKLHAVPAGNTVKFRCPAA GNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWS LVMESVVPSDRGTYTCLVENAVGSIRYNYLLDVL ERSPHRPILQAGLPANTTAVVGSDVELLCKVYS DAQPHIQ

Frame 1

ARGHAAVAGTFLAPGRGALGLSADPAACRGRGR LELGVRRRRSQVRRSQVSRTLCWARSHAGSRKA VGGKSSLGP*EL*EGDAAAAGPVGGPAECAWASS LVPGGL*GSGAWW*ETLAGSEGMPGETDLPLLD LRCFPLSLM*TP*PPATMMRTPSPIGTPRIGTV TPSKHPTGHTPSAWRRNCMQYLRGTPSSSAVQLQ ATPRPPSAGLRMDRPFMGRTALEAFGCAISTGV S*WRAWCPRTAAHTPAW*RTLWAASAITTC*MC WSGPRTGPSCRPGSRPTPQPWWAATWSCCARCTA MPSPTSS

Frame 2

LAATPPSRVHSSLPAEERSGCLRTLPRAGVAAG WSWE*GGGGAR*GGAR*AGPCAGRGVTQARGRQ LVGSPAWVPESCEKEMRLLLALLGVLLSVPGPP VLSLEASEEVELGGKRL*QGVKGCLGRQTCPSWT LDASLCP*CRLLDLQQR**GPQVP*GPLE*AQL PPASTLLDTPPAHGEETACSTCGEHRQVPLSSC RQPHAHHPLA*GWTGLSWGEPHWRHSAAPSALES RDGERGALGPRHIHLPGRERCGQHPL*LPARCA GAVPAPAHPAGRAPGQHHSRGGQRRGAAVQGVQ RCPAPHPV

Sequence FGFR4.bAug05

CGCTCGCGGCCACGCCGCCGTCGCGGGTACATTCCTCGCTCCCGGCCGAGGAGCGCTCGGGCTGTCTGCGGACCCTGCCGCGTGCAGGGGTCGCGGCCGG CTGGAGCTGGGAGTGAGGCGGCGGAGGAGCCAGGTGAGGAGGAGCCAGGTGAGCAGGACCCTGTGCTGGGCGCGGAGTCACGCAGGCTCGAGGAAGGCAG TTGGTGGGAAGTCCAGCTTGGGTCCCTGAGAGCTGTGAGAAGGAGATGCGGCTGCTGCTGGCCCTGTTGGGGGTCCTGCTGAGTGTGCCTGGGCCTCCAG TCTTGTCCCTGGAGGCCTCTGAGGAAGTGGAGCTTGAGCCCTGCCTGGCTCCCAGCCTGGAGCAGCAAGAGCAGGAGCTGACAGTAGCCCTTGGGCAGCC TGTGCGTCTGTGCTGTGGGCGGGCTGAGCGTGGTGGCCACTGGTACAAGGAGGGCAGTCGCCTGGCACCTGCTGGCCGTGTACGGGGCTGGAGGGGCCGC CTAGAGATTGCCAGCTTCCTACCTGAGGATGCTGGCCGCTACCTCTGCCTGGCACGAGGCTCCATGATCGTCCTGCAGAATCTCACCTTGATTACAGGTG ACTCCTTGACCTCCAGCAACGATGATGAGGACCCCAAGTCCCATAGGGACCCCTCGAATAGGCACAGTTACCCCCAGCAAGCACCCTACTGGACACACCC CCAGCGCATGGAGAAGAAACTGCATGCAGTACCTGCGGGGAACACCGTCAAGTTCCGCTGTCCAGCTGCAGGCAACCCCACGCCCACCATCCGCTGGCTT AAGGATGGACAGGCCTTTCATGGGGAGAACCGCATTGGAGGCATTCGGCTGCGCCATCAGCACTGGAGTCTCGTGATGGAGAGCGTGGTGCCCTCGGACC GCGGCACATACACCTGCCTGGTAGAGAACGCTGTGGGCAGCATCCGCTATAACTACCTGCTAGATGTGCTGGAGCGGTCCCCGCACCGGCCCATCCTGCA GGCCGGGCTCCCGGCCAACACCACAGCCGTGGTGGGCAGCGACGTGGAGCTGCTGTGCAAGGTGTACAGCGATGCCCAGCCCCACATCCAGTGGCTGAAG CACATCGTCATCAACGGCAGCAGCTTCGGAGCCGACGGTTTCCCCTATGTGCAAGTCCTAAAGACTGCAGACATCAATAGCTCAGAGGTGGAGGTCCTGT ACCTGCGGAACGTGTCAGCCGAGGACGCAGGCGAGTACACCTGCCTCGCAGGCAATTCCATCGGCCTCTCCTACCAGTCTGCCTGGCTCACGGTGCTGCC AGAGGAGGACCCCACATGGACCGCAGCAGCGCCCGAGGCCAGGTATACGGACATCATCCTGTACGCGTCGGGCTCCCTGGCCTTGGCTGTGCTCCTGCTG CTGGCCGGGCTGTATCGAGGGCAGGCGCTCCACGGCCGGCACCCCCGCCCGCCCGCCACTGTGCAGAAGCTCTCCCGCTTCCCTCTGGCCCGACAGTTCT CCCTGGAGTCAGGCTCTTCCGGCAAGTCAAGCTCATCCCTGGTACGAGGCGTGCGTCTCTCCTCCAGCGGCCCCGCCTTGCTCGCCGGCCTCGTGAGTCT AGATCTACCTCTCGACCCACTATGGGAGTTCCCCCGGGACAGGCTGGTGCTTGGGAAGCCCCTAGGCGAGGGCTGCTTTGGCCAGGTAGTACGTGCAGAG GCCTTTGGCATGGACCCTGCCCGGCCTGACCAAGCCAGCACTGTGGCCGTCAAGATGCTCAAAGACAACGCCTCTGACAAGGACCTGGCCGACCTGGTCT CGGAGATGGAGGTGATGAAGCTGATCGGCCGACACAAGAACATCATCAACCTGCTTGGTGTCTGCACCCAGGAAGGGCCCCTGTACGTGATCGTGGAGTG CGCCGCCAAGGGAAACCTGCGGGAGTTCCTGCGGGCCCGGCGCCCCCCAGGCCCCGACCTCAGCCCCGACGGTCCTCGGAGCAGTGAGGGGCCGCTCTCC TTCCCAGTCCTGGTCTCCTGCGCCTACCAGGTGGCCCGAGGCATGCAGTATCTGGAGTCCCGGAAGTGTATCCACCGGGACCTGGCTGCCCGCAATGTGC TGGTGACTGAGGACAATGTGATGAAGATTGCTGACTTTGGGCTGGCCCGCGGCGTCCACCACATTGACTACTATAAGAAAACCAGCAACGGCCGCCTGCC TGTGAAGTGGATGGCGCCCGAGGCCTTGTTTGACCGGGTGTACACACACCAGAGTGACGTGTGGTCTTTTGGGATCCTGCTATGGGAGATCTTCACCCTC GGGGGCTCCCCGTATCCTGGCATCCCGGTGGAGGAGCTGTTCTCGCTGCTGCGGGAGGGACATCGGATGGACCGACCCCCACACTGCCCCCCAGAGCTGT ACGGGCTGATGCGTGAGTGCTGGCACGCAGCGCCCTCCCAGAGGCCTACCTTCAAGCAGCTGGTGGAGGCGCTGGACAAGGTCCTGCTGGCCGTCTCTGA GGAGTACCTCGACCTCCGCCTGACCTTCGGACCCTATTCCCCCTCTGGTGGGGACGCCAGCAGCACCTGCTCCTCCAGCGATTCTGTCTTCAGCCACGAC CCCCTGCCATTGGGATCCAGCTCCTTCCCCTTCGGGTCTGGGGTGCAGACATGAGCAAGGCTCAAGGCTGTGCAGGCACATAGGCTGGTGGCCTTGGGCC TTGGGGCTCAGCCACAGCCTGACACAGTGCTCGACCTTGATAGCATGGGGCCCCTGGCCCAGAGTTGCTGTGCCGTGTCCAAGGGCCGTGCCCTTGCCCT TGGAGCTGCCGTGCCTGTGTCCTGATGGCCCAAATGTCAGGGTTCTGCTCGGCTTCTTGGACCTTGGCGCTTAGTCCCCATCCCGGGTTTGGCTGAGCCT GGCTGGAGAGCTGCTATGCTAAACCTCCTGCCTCCCAATACCAGCAGGAGGTTCTGGGCCTCTGAACCCCCTTTCCCCACACCTCCCCCTGCTGCTGCTG CCCCAGCGTCTTGACGGGAGCATTGGCCCCTGAGCCCAGAGAAGCTGGAAGCCTGCCGAAAACAGGAGCAAATGGCGTTTTATAAATTATTTTTTTGAAA TAAAGCTCTGTGTGCCTGGGTC

FGFR4.F7 (forward primer)
FGFR4.R1 (reverse primer)
Alternative donor

Frame 0

RSRPRRRRGYIPRSRPRSARAVCGPCRVQGSRP AGAGSEAAEEPGEEEPGEQDPVLGAESRRLEEGS WWEVQLGSLRAVRRRCGCCWPCWGSC*VCLGLQ SCPWRPLRKWSLSPAWLPAWSSKSRS*Q*PLGS LCVCAVGGLSVVATGTRRAVAWHLLAVYGAGGAA *RLPASYLRMLAATSAWHEAP*SSCRISP*LQV TP*PPATMMRTPSPIGTPRIGTVTPSKHPTGHT PSAWRRNCMQYLRGTPSSSAVQLQATPRPPSAGL RMDRPFMGRTALEAFGCAISTGVS*WRAWCPRT AAHTPAW*RTLWAASAITTC*MCWSGPRTGPSC RPGSRPTPQPWWAATWSCCARCTAMPSPTSSG*S TSSSTAAASEPTVSPMCKS*RLQTSIAQRWRSC TCGTCQPRTQASTPASQAIPSASPTSLPGSRCC QRRTPHGPQQRPRPGIRTSSCTRRAPWPWLCSCC WPGCIEGRRSTAGTPARPPLCRSSPASLWPDSS PWSQALPASQAHPWYEACVSPPAAPPCSPAS*V *IYLSTHYGSSPGTGWCLGSP*ARAALAR*YVQR PLAWTLPGLTKPALWPSRCSKTTPLTRTWPTWS RRWR**S*SADTRTSSTCLVSAPRKGPCT*SWS APPRETCGSSCGPGAPQAPTSAPTVLGAVRGRSP SQSWSPAPTRWPEACSIWSPGSVSTGTWLPAMC W*LRTM**RLLTLGWPAASTTLTTIRKPATAAC L*SGWRPRPCLTGCTHTRVTCGLLGSCYGRSSPS GAPRILASRWRSCSRCCGRDIGWTDPHTAPQSC TG*CVSAGTQRPPRGLPSSSWWRRWTRSCWPSL RSTSTSA*PSDPIPPLVGTPAAPAPPAILSSATT PCHWDPAPSPSGLGCRHEQGSRLCRHIGWWPWA LGLSHSLTQCSTLIAWGPWPRVAVPCPRAVPLP LELPCLCPDGPNVRVLLGFLDLGA*SPSRVWLSL AGELLC*TSCLPIPAGGSGPLNPLSPHLPLLLL PQRLDGSIGP*AQRSWKPAENRSKWRFINYFFE IKLCVPG

Frame 1

ARGHAAVAGTFLAPGRGALGLSADPAACRGRGR LELGVRRRRSQVRRSQVSRTLCWARSHAGSRKA VGGKSSLGP*EL*EGDAAAAGPVGGPAECAWASS LVPGGL*GSGA*ALPGSQPGAARAGADSSPWAA CASVLWAG*AWWPLVQGGQSPGTCWPCTGLEGP PRDCQLPT*GCWPLPLPGTRLHDRPAESHLDYR* LLDLQQR**GPQVP*GPLE*AQLPPASTLLDTP PAHGEETACSTCGEHRQVPLSSCRQPHAHHPLA *GWTGLSWGEPHWRHSAAPSALESRDGERGALGP RHIHLPGRERCGQHPL*LPARCAGAVPAPAHPA GRAPGQHHSRGGQRRGAAVQGVQRCPAPHPVAE AHRHQRQQLRSRRFPLCASPKDCRHQ*LRGGGPV PAERVSRGRRRVHLPRRQFHRPLLPVCLAHGAA RGGPHMDRSSARGQVYGHHPVRVGLPGLGCAPA AGRAVSRAGAPRPAPPPARHCAEALPLPSGPTVL PGVRLFRQVKLIPGTRRASLLQRPRLARRPRES RSTSRPTMGVPPGQAGAWEAPRRGLLWPGSTCR GLWHGPCPA*PSQHCGRQDAQRQRL*QGPGRPGL GDGGDEADRPTQEHHQPAWCLHPGRAPVRDRGV RRQGKPAGVPAGPAPPRPRPQPRRSSEQ*GAAL LPSPGLLRLPGGPRHAVSGVPEVYPPGPGCPQCA GD*GQCDEDC*LWAGPRRPPH*LL*ENQQRPPA CEVDGARGLV*PGVHTPE*RVVFWDPAMGDLHP RGLPVSWHPGGGAVLAAAGGTSDGPTPTLPPRAV RADA*VLARSALPEAYLQAAGGGAGQGPAGRL* GVPRPPPDLRTLFPLWWGRQQHLLLQRFCLQPR PPAIGIQLLPLRVWGADMSKAQGCAGT*AGGLGP WGSATA*HSARP**HGAPGPELLCRVQGPCPCP WSCRACVLMAQMSGFCSASWTLALSPHPGFG*A WLESCYAKPPASQYQQEVLGL*TPFPHTSPCCCC PSVLTGALAPEPREAGSLPKTGANGVL*IIFLK *SSVCLG

Frame 2

LAATPPSRVHSSLPAEERSGCLRTLPRAGVAAG WSWE*GGGGAR*GGAR*AGPCAGRGVTQARGRQ LVGSPAWVPESCEKEMRLLLALLGVLLSVPGPP VLSLEASEEVELEPCLAPSLEQQEQELTVALGQP VRLCCGRAERGGHWYKEGSRLAPAGRVRGWRGR LEIASFLPEDAGRYLCLARGSMIVLQNLTLITG DSLTSSNDDEDPKSHRDPSNRHSYPQQAPYWTHP QRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWL KDGQAFHGENRIGGIRLRHQHWSLVMESVVPSD RGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQ AGLPANTTAVVGSDVELLCKVYSDAQPHIQWLK HIVINGSSFGADGFPYVQVLKTADINSSEVEVL YLRNVSAEDAGEYTCLAGNSIGLSYQSAWLTVLP EEDPTWTAAAPEARYTDIILYASGSLALAVLLL LAGLYRGQALHGRHPRPPATVQKLSRFPLARQF SLESGSSGKSSSSLVRGVRLSSSGPALLAGLVSL DLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAE AFGMDPARPDQASTVAVKMLKDNASDKDLADLV SEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVEC AAKGNLREFLRARRPPGPDLSPDGPRSSEGPLS FPVLVSCAYQVARGMQYLESRKCIHRDLAARNV LVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLP VKWMAPEALFDRVYTHQSDVWSFGILLWEIFTL GGSPYPGIPVEELFSLLREGHRMDRPPHCPPEL YGLMRECWHAAPSQRPTFKQLVEALDKVLLAVSE EYLDLRLTFGPYSPSGGDASSTCSSSDSVFSHD PLPLGSSSFPFGSGVQT*ARLKAVQAHRLVALG LGAQPQPDTVLDLDSMGPLAQSCCAVSKGRALAL GAAVPVS*WPKCQGSARLLGPWRLVPIPGLAEP GWRAAMLNLLPPNTSRRFWASEPPFPTPPPAAA APAS*REHWPLSPEKLEACRKQEQMAFYKLFF*N KALCAWV