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Sequences

Sequence ADAM15.dAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGGCTGAGCTGGCTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAGTCTCAGGGGC
CAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCTGGAATCCCGCCCCT
AGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAGCCGGACTTAGGGCT
TCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCCACGCGCTGTCAAGC
AACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAGCCTGTCTCTGCTCA
GTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKAELADRPNPPTRPLPADPVVRSPKSQG
PAKPPPPRKPLPADPQGRCPSGDLPGPGAGIPPL
VVPSRPAPPPPTVSSLYL*PLRRFRCLQAGLRA
SRGGRALWSPLP*LKAPETGGVLRLRAPPRAVK
QHSADLPA*LQRGLGEGLGVGRD*GRSAQPVSAQ
LQ*T*HLGSVPQ

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALRLSWLTDPIPLPALCPLTRW*EARSLRG
QPSPHPQGSHCLPTPRAGAHRVTCPAQGLESRP
*WYPPDQRHRLRQCPRSTSDLSGGSAASKPDLGL
QEAGVPSGVPYHD*RRQRLAVS*DSGHRHALSS
NTLRTCRRSCSGGLGRGWGLDGIEEGPHSLSLL
SCNKRDILGAFPR

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*G*AG*PTQSPYPPSAR*PGGEKPEVSGA
SQAPTPKEATACRPPGPVPIG*PARPRGWNPAP
SGTLQTSATASDSVLALPLTSPEVPLPPSRT*G
FKRRACPLESPTMTEGARDWRCLKTPGTATRCQA
TLCGPAGVVAAGAWGGAGGWTGLRKVRTACLCS
VAINVTSWERSP

Sequence ADAM15.cAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGCAGGCTAGTGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGTCTCAGG
GGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCTGGAATCCCGCC
CCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAGCCGGACTTAGG
GCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCCACGCGCTGTCA
AGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAGCCTGTCTCTGC
TCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKQASALSFPAPPSRPLPPDPVSKRLQSQ
GPAKPPPPRKPLPADPQGRCPSGDLPGPGAGIPP
LVVPSRPAPPPPTVSSLYL*PLRRFRCLQAGLR
ASRGGRALWSPLP*LKAPETGGVLRLRAPPRAV
KQHSADLPA*LQRGLGEGLGVGRD*GRSAQPVSA
QLQ*T*HLGSVPQ

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALSRLVLSASRPPLPGRCRLTLCPRDSSLR
GQPSPHPQGSHCLPTPRAGAHRVTCPAQGLESR
P*WYPPDQRHRLRQCPRSTSDLSGGSAASKPDLG
LQEAGVPSGVPYHD*RRQRLAVS*DSGHRHALS
SNTLRTCRRSCSGGLGRGWGLDGIEEGPHSLSL
LSCNKRDILGAFPR

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*AG*CSQLPGPPFQAAAA*PCVQETPVSG
ASQAPTPKEATACRPPGPVPIG*PARPRGWNPA
PSGTLQTSATASDSVLALPLTSPEVPLPPSRT*
GFKRRACPLESPTMTEGARDWRCLKTPGTATRCQ
ATLCGPAGVVAAGAWGGAGGWTGLRKVRTACLC
SVAINVTSWERSP

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