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Sequences

Sequence ADAM15.gAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGGCTAGTGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGGCTGAGCTGG
CTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAGGTAACGGTGGGGGGAGAGAAGGGCACGGCCTCTCCCCC
CACCTAGGGCTGTGGTGCTGGTAGCCATGACGGTGGTGGCCGTGGCGAGATGCCCCCTCAGTGCATGAGGGCACATATCCCGGTGGTGCCTTTAATGGTG
ACAGTCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCT
GGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAG
CCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCC
ACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAG
CCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Intron retention

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKASALSFPAPPSRPLPPDPVSKRLQAEL
ADRPNPPTRPLPADPVVRSPKVTVGGEKGTASPP
T*GCGAGSHDGGGRGEMPPQCMRAHIPVVPLMV
TVSGASQAPTPKEATACRPPGPVPIG*PARPRG
WNPAPSGTLQTSATASDSVLALPLTSPEVPLPPS
RT*GFKRRACPLESPTMTEGARDWRCLKTPGTA
TRCQATLCGPAGVVAAGAWGGAGGWTGLRKVRT
ACLCSVAINVTSWERSP

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALRLVLSASRPPLPGRCRLTLCPRDSRLSW
LTDPIPLPALCPLTRW*EARR*RWGERRARPLP
PPRAVVLVAMTVVAVARCPLSA*GHISRWCL*W*
QSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGA
GIPPLVVPSRPAPPPPTVSSLYL*PLRRFRCLQ
AGLRASRGGRALWSPLP*LKAPETGGVLRLRAPP
RAVKQHSADLPA*LQRGLGEGLGVGRD*GRSAQ
PVSAQLQ*T*HLGSVPQ

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*G*CSQLPGPPFQAAAA*PCVQETPG*AG
*PTQSPYPPSAR*PGGEKPEGNGGGREGHGLSP
HLGLWCW*P*RWWPWRDAPSVHEGTYPGGAFNG
DSLRGQPSPHPQGSHCLPTPRAGAHRVTCPAQGL
ESRP*WYPPDQRHRLRQCPRSTSDLSGGSAASK
PDLGLQEAGVPSGVPYHD*RRQRLAVS*DSGHR
HALSSNTLRTCRRSCSGGLGRGWGLDGIEEGPHS
LSLLSCNKRDILGAFPR

Sequence ADAM15.iAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGGCTGAGCTGGCTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAGGTAACGGTGG
GGGGAGAGAAGGGCACGGCCTCTCCCCCCACCTAGGGCTGTGGTGCTGGTAGCCATGACGGTGGTGGCCGTGGCGAGATGCCCCCTCAGTGCATGAGGGC
ACATATCCCGGTGGTGCCTTTAATGGTGACAGTCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCC
ATCGGGTGACCT
GCCCGGCCCAGGGGCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGA
CCTCTCCGGAGGTTCCGCTGCCTCCAAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTG
GCGGTGTCTTAAGACTCCGGGCACCGCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGT
TGGACGGGATTGAGGAAGGTCCGCACAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Intron retention

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKAELADRPNPPTRPLPADPVVRSPKVTV
GGEKGTASPPT*GCGAGSHDGGGRGEMPPQCMRA
HIPVVPLMVTVSGASQAPTPKEATACRPPGPVP
IG*P
ARPRGWNPAPSGTLQTSATASDSVLALPL
TSPEVPLPPSRT*GFKRRACPLESPTMTEGARDW
RCLKTPGTATRCQATLCGPAGVVAAGAWGGAGG
WTGLRKVRTACLCSVAINVTSWERSP

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALRLSWLTDPIPLPALCPLTRW*EARR*RW
GERRARPLPPPRAVVLVAMTVVAVARCPLSA*G
HISRWCL*W*QSQGPAKPPPPRKPLPADPQGRCP
SGDL
PGPGAGIPPLVVPSRPAPPPPTVSSLYL*
PLRRFRCLQAGLRASRGGRALWSPLP*LKAPET
GGVLRLRAPPRAVKQHSADLPA*LQRGLGEGLGV
GRD*GRSAQPVSAQLQ*T*HLGSVPQ

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*G*AG*PTQSPYPPSAR*PGGEKPEGNGG
GREGHGLSPHLGLWCW*P*RWWPWRDAPSVHEG
TYPGGAFNGDSLRGQPSPHPQGSHCLPTPRAGA
HRVT
CPAQGLESRP*WYPPDQRHRLRQCPRSTSD
LSGGSAASKPDLGLQEAGVPSGVPYHD*RRQRL
AVS*DSGHRHALSSNTLRTCRRSCSGGLGRGWG
LDGIEEGPHSLSLLSCNKRDILGAFPR

Sequence ADAM15.fAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGCAGGCTAGTGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGGCTGAGC
TGGCTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAGGTAACGGTGGGGGGAGAGAAGGGCACGGCCTCTCC
CCCCACCTAGGGCTGTGGTGCTGGTAGCCATGACGGTGGTGGCCGTGGCGAGATGCCCCCTCAGTGCATGAGGGCACATATCCCGGTGGTGCCTTTAATG
GTGACAGTCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGG
GCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCC
AAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACC
GCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCA
CAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Intron retention

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKQASALSFPAPPSRPLPPDPVSKRLQAE
LADRPNPPTRPLPADPVVRSPKVTVGGEKGTASP
PT*GCGAGSHDGGGRGEMPPQCMRAHIPVVPLM
VTVSGASQAPTPKEATACRPPGPVPIG*PARPR
GWNPAPSGTLQTSATASDSVLALPLTSPEVPLPP
SRT*GFKRRACPLESPTMTEGARDWRCLKTPGT
ATRCQATLCGPAGVVAAGAWGGAGGWTGLRKVR
TACLCSVAINVTSWERSP

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALSRLVLSASRPPLPGRCRLTLCPRDSRLS
WLTDPIPLPALCPLTRW*EARR*RWGERRARPL
PPPRAVVLVAMTVVAVARCPLSA*GHISRWCL*W
*QSQGPAKPPPPRKPLPADPQGRCPSGDLPGPG
AGIPPLVVPSRPAPPPPTVSSLYL*PLRRFRCL
QAGLRASRGGRALWSPLP*LKAPETGGVLRLRAP
PRAVKQHSADLPA*LQRGLGEGLGVGRD*GRSA
QPVSAQLQ*T*HLGSVPQ

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*AG*CSQLPGPPFQAAAA*PCVQETPG*A
G*PTQSPYPPSAR*PGGEKPEGNGGGREGHGLS
PHLGLWCW*P*RWWPWRDAPSVHEGTYPGGAFN
GDSLRGQPSPHPQGSHCLPTPRAGAHRVTCPAQG
LESRP*WYPPDQRHRLRQCPRSTSDLSGGSAAS
KPDLGLQEAGVPSGVPYHD*RRQRLAVS*DSGH
RHALSSNTLRTCRRSCSGGLGRGWGLDGIEEGPH
SLSLLSCNKRDILGAFPR

Sequence ADAM15.uAug05

CATGCTTTATCTTGCCCCCTCGGCCCTCTCTTTCTGACCCCCCTTTGCTGCTGGTTCCCTGAGTCTGTGCCCCTTGAACCCTTCACTCTCCCTGATCACT
TGACTTCACTCCCTGCCCCCTGCGCCTTCATGGATCTAGAGTTCTTAGCCCCGTCCTCCCTTAAACCTGACTTCCGCCCACAGCAACCAGCTCCCTGACC
ACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCGCCTGCACCAGCGACTCTGCCAGCTCA
AGGGAC
CCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTGCTGGCACGAGGCACTAAGCAGGCTAG
TGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGGTAAATCTGGGCCAGGGCCCGCCCTGAGCCAAG
GCAGGTGGGAGGCTTGGTACCCAACTGCAGTTCTCATCCCTGCTCCCTGCCAGTGGTGCTCTTCATTAGGTGATCGGGGTGCCCCTCAGCCTTCAGACAC
TCTGAGCCCCAGAAGCAGCAAAGGGTGAGCCTCCTGCCTTGGTTTCTACCACCATCTGGTGGTCAATGGCGGGACTGCAGTCGGCCAGGGACTGCGGTTG
ACCTACACCTTCCTCCCCTGAGACATCAGCTGGCATGCCTCCAAGCCCTCTGCGCATGCCCTCATTCTCTCCTGCCCCCTGGCTGACTTTGCATGTTGAC
TTGAACCCCTCTGGGGAATCTCTGTGCATGTCCACAGCCCCTGGTTATGCTCTCACAGCCACTGCCCCTCTCTCTGTTCAGGCTGAGCTGGCTGACCGAC
CCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAGGTAACGGTGGGGGGAGAGAAGGGCACGGCCTCTCCCCCCACCTAGGG
CTGTGGTGCTGGTAGCCATGACGGTGGTGGCCGTGGCGAGATGCCCCCTCAGTGCATGAGGGCACATATCCCGGTGGTGCCTTTAATGGTGACAGGTTTG
TTTGCAGACAAGGGTGACCGCTGGTGCTGCCCCCAAGCTGGTGTTCCCCAGCACCAGTGCGTTGGGGGTGGGCAACATGACACCCCCCCACCTAAGCCGG
CCTCCTGCCTTCTCTCCCTCAG
TCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGAC
CT
GCCCGGCCCAGGGGCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGA
GGTTCCGCTGCCTCCAAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTT
AAGACTCCGGGCACCGCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGAT
TGAGGAAGGTCCGCACAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Intron retention

Frame 0

HALSCPLGPLFLTPLCCWFPESVPLEPFTLPDH
LTSLPAPCAFMDLEFLAPSSLKPDFRPQQPAP*P
QGCSSASWSYWSW*CLVPATGTVPACTSDSASS
RD
PPASTGQPNLVPLNGQDLRRGPCWHEALSRL
VLSASRPPLPGRCRLTLCPRDSR*IWARARPEPR
QVGGLVPNCSSHPCSLPVVLFIR*SGCPSAFRH
SEPQKQQRVSLLPWFLPPSGGQWRDCSRPGTAV
DLHLPPLRHQLACLQALCACPHSLLPPG*LCMLT
*TPLGNLCACPQPLVMLSQPLPLSLFRLSWLTD
PIPLPALCPLTRW*EARR*RWGERRARPLPPPR
AVVLVAMTVVAVARCPLSA*GHISRWCL*W*QVC
LQTRVTAGAAPKLVFPSTSALGVGNMTPPHLSR
PPAFSPS
VSGASQAPTPKEATACRPPGPVPIG*
P
ARPRGWNPAPSGTLQTSATASDSVLALPLTSPE
VPLPPSRT*GFKRRACPLESPTMTEGARDWRCL
KTPGTATRCQATLCGPAGVVAAGAWGGAGGWTG
LRKVRTACLCSVAINVTSWERSP

Frame 1

MLYLAPSALSF*PPFAAGSLSLCPLNPSLSLIT
*LHSLPPAPSWI*SS*PRPPLNLTSAHSNQLPD
HRAAPQPPGLIGPGDAWCQLLVPCPPAPATLPAQ
GT
HLPVQGSPIWSL*TARTSAEGPAGTRH*AG*
CSQLPGPPFQAAAA*PCVQETPGKSGPGPALSQ
GRWEAWYPTAVLIPAPCQWCSSLGDRGAPQPSDT
LSPRSSKG*ASCLGFYHHLVVNGGTAVGQGLRL
TYTFLP*DISWHASKPSAHALILSCPLADFAC*
LEPLWGISVHVHSPWLCSHSHCPSLCSG*AG*PT
QSPYPPSAR*PGGEKPEGNGGGREGHGLSPHLG
LWCW*P*RWWPWRDAPSVHEGTYPGGAFNGDRF
VCRQG*PLVLPPSWCSPAPVRWGWAT*HPPT*AG
LLPSLPQ
SQGPAKPPPPRKPLPADPQGRCPSGD
L
PGPGAGIPPLVVPSRPAPPPPTVSSLYL*PLR
RFRCLQAGLRASRGGRALWSPLP*LKAPETGGVL
RLRAPPRAVKQHSADLPA*LQRGLGEGLGVGRD
*GRSAQPVSAQLQ*T*HLGSVPQ

Frame 2

CFILPPRPSLSDPPLLLVP*VCAP*TLHSP*SL
DFTPCPLRLHGSRVLSPVLP*T*LPPTATSSLT
TGLLLSLLVLLVLVMLGASYWYRARLHQRLCQL
KG
PTCQYRAAQSGPSERPGPPQRALLARGTKQAS
ALSFPAPPSRPLPPDPVSKRLQVNLGQGPP*AK
AGGRLGTQLQFSSLLPASGALH*VIGVPLSLQT
L*APEAAKGEPPALVSTTIWWSMAGLQSARDCG*
PTPSSPETSAGMPPSPLRMPSFSPAPWLTLHVD
LNPSGESLCMSTAPGYALTATAPLSVQAELADR
PNPPTRPLPADPVVRSPKVTVGGEKGTASPPT*G
CGAGSHDGGGRGEMPPQCMRAHIPVVPLMVTGL
FADKGDRWCCPQAGVPQHQCVGGGQHDTPPPKP
ASCLLSLS
LRGQPSPHPQGSHCLPTPRAGAHRVT
CPAQGLESRP*WYPPDQRHRLRQCPRSTSDLSG
GSAASKPDLGLQEAGVPSGVPYHD*RRQRLAVS
*DSGHRHALSSNTLRTCRRSCSGGLGRGWGLDGI
EEGPHSLSLLSCNKRDILGAFPR

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