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Sequences

Sequence ADAM15.kAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGTCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACC CCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTC CTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTG AAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTG GGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA

ADAM15.F7 (forward primer)
ADAM15.R2 (reverse primer)
Multiple exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN SICSPDFSGGVNMDHSTSILGVASSIAHELGHS LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR LHQRLCQLKGPTCQYSLRGQPSPHPQGSHCLPT PRAGAHRVTCPAQGLESRP*WYPPDQRHRLRQC PRSTSDLSGGSAASKPDLGLQEAGVPSGVPYHD* RRQRLAVS*DSGHRHALSSNTLRTCRRSCSGGL GRGWGLDGIEEGPHSLSLLSCNKRDILGAFPR

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC SALAALARPGAPLPCGWRCSGPWGSWARAALCL PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP* MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP ACTSDSASSRDPPASTVSGASQAPTPKEATACRP PGPVPIG*PARPRGWNPAPSGTLQTSATASDSV LALPLTSPEVPLPPSRT*GFKRRACPLESPTMT EGARDWRCLKTPGTATRCQATLCGPAGVVAAGAW GGAGGWTGLRKVRTACLCSVAINVTSWERSP

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR *R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE *GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL *LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR* DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP PAPATLPAQGTHLPVQSQGPAKPPPPRKPLPAD PQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPTVS SLYL*PLRRFRCLQAGLRASRGGRALWSPLP*L KAPETGGVLRLRAPPRAVKQHSADLPA*LQRGL GEGLGVGRD*GRSAQPVSAQLQ*T*HLGSVPQ

Sequence ADAM15.gAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG CTGGCACGAGGCACTAAGGCTAGTGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGGCTGAGCTGG CTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAGGTAACGGTGGGGGGAGAGAAGGGCACGGCCTCTCCCCC CACCTAGGGCTGTGGTGCTGGTAGCCATGACGGTGGTGGCCGTGGCGAGATGCCCCCTCAGTGCATGAGGGCACATATCCCGGTGGTGCCTTTAATGGTG ACAGTCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCT GGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAG CCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCC ACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAG CCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA

ADAM15.F7 (forward primer)
ADAM15.R2 (reverse primer)
Multiple exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN SICSPDFSGGVNMDHSTSILGVASSIAHELGHS LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL LARGTKASALSFPAPPSRPLPPDPVSKRLQAEL ADRPNPPTRPLPADPVVRSPKVTVGGEKGTASPP T*GCGAGSHDGGGRGEMPPQCMRAHIPVVPLMV TVSGASQAPTPKEATACRPPGPVPIG*PARPRG WNPAPSGTLQTSATASDSVLALPLTSPEVPLPPS RT*GFKRRACPLESPTMTEGARDWRCLKTPGTA TRCQATLCGPAGVVAAGAWGGAGGWTGLRKVRT ACLCSVAINVTSWERSP

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC SALAALARPGAPLPCGWRCSGPWGSWARAALCL PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP* MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC WHEALRLVLSASRPPLPGRCRLTLCPRDSRLSW LTDPIPLPALCPLTRW*EARR*RWGERRARPLP PPRAVVLVAMTVVAVARCPLSA*GHISRWCL*W* QSQGPAKPPPPRKPLPADPQGRCPSGDLPGPGA GIPPLVVPSRPAPPPPTVSSLYL*PLRRFRCLQ AGLRASRGGRALWSPLP*LKAPETGGVLRLRAPP RAVKQHSADLPA*LQRGLGEGLGVGRD*GRSAQ PVSAQLQ*T*HLGSVPQ

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR *R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE *GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL *LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR* DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP AGTRH*G*CSQLPGPPFQAAAA*PCVQETPG*AG *PTQSPYPPSAR*PGGEKPEGNGGGREGHGLSP HLGLWCW*P*RWWPWRDAPSVHEGTYPGGAFNG DSLRGQPSPHPQGSHCLPTPRAGAHRVTCPAQGL ESRP*WYPPDQRHRLRQCPRSTSDLSGGSAASK PDLGLQEAGVPSGVPYHD*RRQRLAVS*DSGHR HALSSNTLRTCRRSCSGGLGRGWGLDGIEEGPHS LSLLSCNKRDILGAFPR