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Sequences

Sequence ADAM15.hAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGTCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGC
CCGGCCCAGGGGCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTT
CCGCTGCCTCCAAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGA
CTCCGGGCACCGCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAG
GAAGGTCCGCACAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Multiple exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKSQGPAKPPPPRKPLPADPQGRCPSGDL
PGPGAGIPPLVVPSRPAPPPPTVSSLYL*PLRRF
RCLQAGLRASRGGRALWSPLP*LKAPETGGVLR
LRAPPRAVKQHSADLPA*LQRGLGEGLGVGRD*
GRSAQPVSAQLQ*T*HLGSVPQ

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALSLRGQPSPHPQGSHCLPTPRAGAHRVTC
PAQGLESRP*WYPPDQRHRLRQCPRSTSDLSGG
SAASKPDLGLQEAGVPSGVPYHD*RRQRLAVS*D
SGHRHALSSNTLRTCRRSCSGGLGRGWGLDGIE
EGPHSLSLLSCNKRDILGAFPR

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*VSGASQAPTPKEATACRPPGPVPIG*PA
RPRGWNPAPSGTLQTSATASDSVLALPLTSPEV
PLPPSRT*GFKRRACPLESPTMTEGARDWRCLK
TPGTATRCQATLCGPAGVVAAGAWGGAGGWTGLR
KVRTACLCSVAINVTSWERSP

Sequence ADAM15.eAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGAGTCCTCCGCCTGGAGTGGGTCGGGGGGCGGACTGGGAGGGAGGTGCAGGAAAGTCGGAAGGCATTAGGGTAATGGG
GCCGGACGGAGACCCTGGGAGAGCCCAGCCAGAGCGCGGCCCGCCCTGGTCCGCTGTCCTGGGCCTAGGGCCCGGTGACTTGGCGATGGGGTGAAAAGAG
AAGGAGGGGGGATGCCGGCGCCCCCTGCCTCCTGCCTGGTCATCCTCTGCGCGGTCCCTGCGGACACTTTCAGGCTCAGGTACCAGGTACCGAGGGGCCT
GTCCAGCGCCACTTCAAGATCGTGATGAGAGGGTCGCTGCTCCCCAGGACTGGCATCTTCGCTGCTCTGGGGCCTAGCTAACCGTTCGACCCGGTGCCAG
GGCGCTGAGCGGGCATGGCTTGTAGGGTTTAGTGAAGAGGATTCTCTCTAGCCTCTATTCCAGGCCTGGGGCCGCCAGGCACTCCTCACCCTGGTGCTGT
TGCCACCAGTGCCTGGCCGAGCGGGAGGGGCCCGAGATGAGCCAGGAGAAGGGAGAATTGGCCAGGAAAGAGGCTGGGACACCAACTCCTCCTTGGAACT
TTCACTTCCCGCTGCTGTCTTGGGCCGGGACCGAGAGGGCAGGCGCGGGTGGAGTGTCCGGAGGAGAGAGGGCCATTGTGTGTTGGGGGGGTGGGGGGTG
CTCGAGGAGGAAGCAGAGGCTGTAGGCAGCGGGTGTGCCTGACTGGGCATGAGGGTGTTTAGGGAGGTGGGGGTGTTTGCACTGCTCACCCAGAAATGGG
CGTTCCTGGCATCTCCGATGTGAGCGAAGGGGAGGGTGAGCGGGCACCCGGCCACAAGGCTTAGCTCAGTCTCGAGAGGGGGCGTTCCTGAAGTGGGGGG
AGAGTGATTGGGAGGGAGTGGGAACCGGGGAGGGTCCTGTGAGAACCTGGGATTGGCCGGAAGGGGACAAGGAGGGCCACAGGCTGCGCAAGCCGAAAGT
CTTTCTTGGGGACTTGTGAATGGGTTGGTGGGTGGAAAGCCATAAATTAGAGAGACACCCTCTCCTTCCAGTATTCTTCTTTAAGTCTCAGCATGCAATG
TGGAAGCCCCTCAGGTACCTAAGGGTCTTGATGGGCTGGGAGCTGGTGGATCTGAGGGCACCTGTCACCCCCAGCCCTGCTGTCGATTCCCTCAGTACTG
TCTTGGGGTGTCCTGGGACCTGCAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACG
ATCTCCCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCT
ACAGAATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGC
TACCAGGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATA
CCCTGGAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGA
ATCTGTACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTG
ATTGTGGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGC
CCCTGAATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCT
CCACTGGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATT
CAGAACTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCC
ACAGCCTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCT
ACCAGGCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCC
CCTATGGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGA
CCTGCCAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGG
GGATTGTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTG
TGCATGCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATA
CTCGGGGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGAC
AGGTAGGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGAC
CTGGGCAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCC
TGGGGGCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCAC
CACTCAGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGT
GCCCGCCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGG
CCCTGCTGGCACGAGGCACTAAGGCTAGTGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGGCTGA
GCTGGCTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAG
TCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGG
AAGCCACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGC
CACCGCCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTG
GAGTCCCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCG
TAGTTGCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTG
GGAGCGTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Multiple exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGESSAWSGSGGGLGGRCRKVGRH*GNG
AGRRPWESPARARPALVRCPGPRAR*LGDGVKR
EGGGMPAPPASCLVILCAVPADTFRLRYQVPRGL
SSATSRS**EGRCSPGLASSLLWGLANRSTRCQ
GAERAWLVGFSEEDSL*PLFQAWGRQALLTLVL
LPPVPGRAGGARDEPGEGRIGQERGWDTNSSLEL
SLPAAVLGRDREGRRGWSVRRREGHCVLGGWGV
LEEEAEAVGSGCA*LGMRVFREVGVFALLTQKW
AFLASPM*AKGRVSGHPATRLSSVSRGGVPEVGG
E*LGGSGNRGGSCENLGLAGRGQGGPQAAQAES
LSWGLVNGLVGGKP*IRETPSPSSILL*VSACN
VEAPQVPKGLDGLGAGGSEGTCHPQPCCRFPQYC
LGVSWDLQVALRSSRQSQRRPRGSPWSPRSFRT
ISQLASKRCFRPVCLSP*GSSWSWTVTVISWSC
YRIGSWSQAAQPWCGTSPMALGWSVRDTLWRTAA
TREECGDMQAPGCPSAPALGSEAWWS*PQREAI
PWSRGLGTFRVLPLFRESKISTCQATPVP*AGG
NLYTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*
LWLITRRPRNTGTSSTC*TAHWKWPSCWTHSSG
P*MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTS
STGAGHICCLDCPMTVPSW*LVLHSLGLRWAWPF
RTPSVLLTSQEV*TWTTPPASWESPPP*PMSWA
TAWAWTMICLGIAAPVQVQPQPRPASWRPPQTS
YQA*TSATAADGPWRKPSWMEWAAASSNGCLAYP
LWLLSAEICLWSRASSVTVASWMTASIPAVIL*
PAS*GQVHSVHLTDPVVKIASCARLAGSVVLPE
GIVTCLNSAQETAPSVPLMSA*GMASPALAGKLC
ACTGVVPPMPSSASHFGDLEPSPLRHFASRQLI
LGEMLLGAVGATPVAVMCPAPLEMPFVGSSSAR
QVGPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWT
WAVMWPSPS*LCLAQPVALAWCV*TIDASVWIS
WGHRNVEANAMDMGSVTATGTATVRRAGHPLTA
PLSSKQPAP*PQGCSSASWSYWSW*CLVPATGTV
PACTSDSASSRDPPASTGQPNLVPLNGQDLRRG
PCWHEALRLVLSASRPPLPGRCRLTLCPRDSRL
SWLTDPIPLPALCPLTRW*EARS
LRGQPSPHPQG
SHCLPTPRAGAHRVTCPAQGLESRP*WYPPDQR
HRLRQCPRSTSDLSGGSAASKPDLGLQEAGVPS
GVPYHD*RRQRLAVS*DSGHRHALSSNTLRTCRR
SCSGGLGRGWGLDGIEEGPHSLSLLSCNKRDIL
GAFPR

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VSPPPGVGRGADWEGGAGKSEGIRVMG
PDGDPGRAQPERGPPWSAVLGLGPGDLAMG*KE
KEGGCRRPLPPAWSSSARSLRTLSGSGTRYRGA
CPAPLQDRDERVAAPQDWHLRCSGA*LTVRPGAR
ALSGHGL*GLVKRILSSLYSRPGAARHSSPWCC
CHQCLAEREGPEMSQEKGELARKEAGTPTPPWN
FHFPLLSWAGTERAGAGGVSGGERAIVCWGGGGC
SRRKQRL*AAGVPDWA*GCLGRWGCLHCSPRNG
RSWHLRCERRGG*AGTRPQGLAQSREGAFLKWG
ESDWEGVGTGEGPVRTWDWPEGDKEGHRLRKPKV
FLGDL*MGWWVESHKLERHPLLPVFFFKSQHAM
WKPLRYLRVLMGWELVDLRAPVTPSPAVDSLST
VLGCPGTCRWH*GAAGRVREGPEGALGAPGPSGR
SPN*PQKGASDQSA*APEDQVGAGR*QSYPGAA
TE*GVGPRPPNPGVVPARWHSGGQ*GTHFGELL
LPGKSAGICRLLGVHLHLLWAQRLGGPDPREKLY
PGAGAWGPSGSSHYFANPRSPPARPHLCPELAG
ICTHSEATRAPPGTAPHSPEAGCGNRDQDCGVG
DCG*SLGGPEIPGLPAPAKPHTGSGPLAGHILPA
PECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLP
PLAQGTFAASIAP*QCPAGDWYFILWAYGGHGH
SELHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGP
QPGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLP
TRPELQQLQPTGPGESPPGWNGQLPLRTAA*PT
PYGCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFD
LPAEARCTVCI*RTLLSKLPAAPVWLAVSSYQR
GL*LA*ILPRRQLPVSP*CQPRGWRALRWRASC
VHARALCLLCPAVPVTLGTWSPARCATLPPDS*Y
SGKCFWELWAQPQWQLCVLHP*RCHLWAAPVPD
R*DPASAGLHPGSTLGDNRCEWD*AELQLGAPG
PGQ*CGPAPPDSAWHSLWPWPGVYRPSMPACGSP
GGTGMSKQMPWTWGL*QQQALLL*GGLGTP*LH
HSAQSNQLPDHRAAPQPPGLIGPGDAWCQLLVP
CPPAPATLPAQGTHLPVQGSPIWSL*TARTSAEG
PAGTRH*G*CSQLPGPPFQAAAA*PCVQETPG*
AG*PTQSPYPPSAR*PGGEKPE
VSGASQAPTPK
EATACRPPGPVPIG*PARPRGWNPAPSGTLQTSA
TASDSVLALPLTSPEVPLPPSRT*GFKRRACPL
ESPTMTEGARDWRCLKTPGTATRCQATLCGPAG
VVAAGAWGGAGGWTGLRKVRTACLCSVAINVTSW
ERSP

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYR*VLRLEWVGGRTGREVQESRKALG*W
GRTETLGEPSQSAARPGPLSWA*GPVTWRWGEKR
RRGDAGAPCLLPGHPLRGPCGHFQAQVPGTEGP
VQRHFKIVMRGSLLPRTGIFAALGPS*PFDPVP
GR*AGMACRV**RGFSLASIPGLGPPGTPHPGAV
ATSAWPSGRGPR*ARRRENWPGKRLGHQLLLGT
FTSRCCLGPGPRGQARVECPEERGPLCVGGVGG
ARGGSRGCRQRVCLTGHEGV*GGGGVCTAHPEMG
VPGISDVSEGEGERAPGHKA*LSLERGRS*SGG
RVIGREWEPGRVL*EPGIGRKGTRRATGCASRK
SFLGTCEWVGGWKAIN*RDTLSFQYSSLSLSMQC
GSPSGT*GS*WAGSWWI*GHLSPPALLSIPSVL
SWGVLGPAGGTEEQQAESEKAPREPLEPQVLQD
DLPISLKKVLQTSLPEPLRIKLELDGDSHILELL
QNRELVPGRPTLVWYQPDGTRVVSEGHTLENCC
YQGRVRGYAGSWVSICTCSGLRGLVVLTPERSY
TLEQGPGDLQGPPIISRIQDLHLPGHTCALSWRE
SVHTQKPPEHPLGQRHIRRRRDVVTETKTVELV
IVADHSEAQKYRDFQHLLNRTLEVALLLDTFFR
PLNVRVALVGLEAWTQRDLVEISPNPAVTLENFL
HWRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAI
QNSICSPDFSGGVNMDHSTSILGVASSIAHELG
HSLGLDHDLPGNSCPCPGPAPAKTCIMEASTDFL
PGLNFSNCSRRALEKALLDGMGSCLFERLPSLP
PMAAFCGNMFVEPGEQCDCGFLDDCVDPCCDSL
TCQLRPGAQCASDGPCCQNCQLRPSGWQCRPTRG
DCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAV
CMHGRCASYAQQCQSLWGPGAQPAAPLCLQTAN
TRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCQT
GRTQPLLGSIRDLLWETIDVNGTELNCSWVHLD
LGSDVAQPLLTLPGTACGPGLVCIDHRCQRVDL
LGAQECRSKCHGHGVCDSNRHCYCEEGWAPPDCT
TQLKATSSLTTGLLLSLLVLLVLVMLGASYWYR
ARLHQRLCQLKGPTCQYRAAQSGPSERPGPPQR
ALLARGTKASALSFPAPPSRPLPPDPVSKRLQAE
LADRPNPPTRPLPADPVVRSPK
SQGPAKPPPPR
KPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPA
PPPPTVSSLYL*PLRRFRCLQAGLRASRGGRALW
SPLP*LKAPETGGVLRLRAPPRAVKQHSADLPA
*LQRGLGEGLGVGRD*GRSAQPVSAQLQ*T*HL
GSVPQ

Sequence ADAM15.bAug05

CTGGGGTGAGCCGCGCACTGCCTCGCCTGCAGTCGGGAAAGCCTGCCCGCCCGACCTCTCCGAGCCAGGCCGCGCACAGGAGGCAGGGAGGCCGCGAAGC
TACTAGGGAGGGGTCCGGACCTGGCGCCGGGTGAAGGCGCGCCGCCCAAGCCGGTCGGACCGGGCACCGGCTCCCACTCCGCACAGTTGCGGGGAAGCGG
TAGCGCTGAGCAGCGCGGGCGTAGTGGGCGGTGTCCCCGCTCCCGAGGCACCCGGCGCGCAGCGGGGCGGGCTTTGCCGGGGGCGGAGCTTGGCTTGGGG
CCGGGTGGGAGGGGGCGGGCCGGGGCGGGGCCTGGTGGCCGCGCGGCGCTGCTGGGTTCTCCGAGGCGACCTGGCCGCCGGCCGCTCCTCCGCGCGCTGT
TCCGCACTTGCTGCCCTCGCCCGGCCCGGAGCGCCGCTGCCATGCGGCTGGCGCTGCTCTGGGCCCTGGGGCTCCTGGGCGCGGGCAGCCCTCTGCCTTC
CTGGCCGCTCCCAAATATAGGTGGCACTGAGGAGCAGCAGGCAGAGTCAGAGAAGGCCCCGAGGGAGCCCTTGGAGCCCCAGGTCCTTCAGGACGATCTC
CCAATTAGCCTCAAAAAGGTGCTTCAGACCAGTCTGCCTGAGCCCCTGAGGATCAAGTTGGAGCTGGACGGTGACAGTCATATCCTGGAGCTGCTACAGA
ATAGGGAGTTGGTCCCAGGCCGCCCAACCCTGGTGTGGTACCAGCCCGATGGCACTCGGGTGGTCAGTGAGGGACACACTTTGGAGAACTGCTGCTACCA
GGGAAGAGTGCGGGGATATGCAGGCTCCTGGGTGTCCATCTGCACCTGCTCTGGGCTCAGAGGCTTGGTGGTCCTGACCCCAGAGAGAAGCTATACCCTG
GAGCAGGGGCCTGGGGACCTTCAGGGTCCTCCCATTATTTCGCGAATCCAAGATCTCCACCTGCCAGGCCACACCTGTGCCCTGAGCTGGCGGGAATCTG
TACACACTCAGAAGCCACCAGAGCACCCCCTGGGACAGCGCCACATTCGCCGGAGGCGGGATGTGGTAACAGAGACCAAGACTGTGGAGTTGGTGATTGT
GGCTGATCACTCGGAGGCCCAGAAATACCGGGACTTCCAGCACCTGCTAAACCGCACACTGGAAGTGGCCCTCTTGCTGGACACATTCTTCCGGCCCCTG
AATGTACGAGTGGCACTAGTGGGCCTGGAGGCCTGGACCCAGCGTGACCTGGTGGAGATCAGCCCAAACCCAGCTGTCACCCTCGAAAACTTCCTCCACT
GGCGCAGGGCACATTTGCTGCCTCGATTGCCCCATGACAGTGCCCAGCTGGTGACTGGTACTTCATTCTCTGGGCCTACGGTGGGCATGGCCATTCAGAA
CTCCATCTGTTCTCCTGACTTCTCAGGAGGTGTGAACATGGACCACTCCACCAGCATCCTGGGAGTCGCCTCCTCCATAGCCCATGAGTTGGGCCACAGC
CTGGGCCTGGACCATGATTTGCCTGGGAATAGCTGCCCCTGTCCAGGTCCAGCCCCAGCCAAGACCTGCATCATGGAGGCCTCCACAGACTTCCTACCAG
GCCTGAACTTCAGCAACTGCAGCCGACGGGCCCTGGAGAAAGCCCTCCTGGATGGAATGGGCAGCTGCCTCTTCGAACGGCTGCCTAGCCTACCCCCTAT
GGCTGCTTTCTGCGGAAATATGTTTGTGGAGCCGGGCGAGCAGTGTGACTGTGGCTTCCTGGATGACTGCGTCGATCCCTGCTGTGATTCTTTGACCTGC
CAGCTGAGGCCAGGTGCACAGTGTGCATCTGACGGACCCTGTTGTCAAAATTGCCAGCTGCGCCCGTCTGGCTGGCAGTGTCGTCCTACCAGAGGGGATT
GTGACTTGCCTGAATTCTGCCCAGGAGACAGCTCCCAGTGTCCCCCTGATGTCAGCCTAGGGGATGGCGAGCCCTGCGCTGGCGGGCAAGCTGTGTGCAT
GCACGGGCGTTGTGCCTCCTATGCCCAGCAGTGCCAGTCACTTTGGGGACCTGGAGCCCAGCCCGCTGCGCCACTTTGCCTCCAGACAGCTAATACTCGG
GGAAATGCTTTTGGGAGCTGTGGGCGCAACCCCAGTGGCAGTTATGTGTCCTGCACCCCTAGAGATGCCATTTGTGGGCAGCTCCAGTGCCAGACAGGTA
GGACCCAGCCTCTGCTGGGCTCCATCCGGGATCTACTCTGGGAGACAATAGATGTGAATGGGACTGAGCTGAACTGCAGCTGGGTGCACCTGGACCTGGG
CAGTGATGTGGCCCAGCCCCTCCTGACTCTGCCTGGCACAGCCTGTGGCCCTGGCCTGGTGTGTATAGACCATCGATGCCAGCGTGTGGATCTCCTGGGG
GCACAGGAATGTCGAAGCAAATGCCATGGACATGGGGTCTGTGACAGCAACAGGCACTGCTACTGTGAGGAGGGCTGGGCACCCCCTGACTGCACCACTC
AGCTCAAAGCAACCAGCTCCCTGACCACAGGGCTGCTCCTCAGCCTCCTGGTCTTATTGGTCCTGGTGATGCTTGGTGCCAGCTACTGGTACCGTGCCCG
CCTGCACCAGCGACTCTGCCAGCTCAAGGGACCCACCTGCCAGTACAGGGCAGCCCAATCTGGTCCCTCTGAACGGCCAGGACCTCCGCAGAGGGCCCTG
CTGGCACGAGGCACTAAGGCTAGTGCTCTCAGCTTCCCGGCCCCCCCTTCCAGGCCGCTGCCGCCTGACCCTGTGTCCAAGAGACTCCAGGCTGAGCTGG
CTGACCGACCCAATCCCCCTACCCGCCCTCTGCCCGCTGACCCGGTGGTGAGAAGCCCGAAG
TCTCAGGGGCCAGCCAAGCCCCCACCCCCAAGGAAGCC
ACTGCCTGCCGACCCCCAGGGCCGGTGCCCATCGGGTGACCTGCCCGGCCCAGGGGCTGGAATCCCGCCCCTAGTGGTACCCTCCAGACCAGCGCCACCG
CCTCCGACAGTGTCCTCGCTCTACCTCTGACCTCTCCGGAGGTTCCGCTGCCTCCAAGCCGGACTTAGGGCTTCAAGAGGCGGGCGTGCCCTCTGGAGTC
CCCTACCATGACTGAAGGCGCCAGAGACTGGCGGTGTCTTAAGACTCCGGGCACCGCCACGCGCTGTCAAGCAACACTCTGCGGACCTGCCGGCGTAGTT
GCAGCGGGGGCTTGGGGAGGGGCTGGGGGTTGGACGGGATTGAGGAAGGTCCGCACAGCCTGTCTCTGCTCAGTTGCAATAAACGTGACATCTTGGGAGC
GTTCCCCAGA
  • ADAM15.F7 (forward primer)
  • ADAM15.R2 (reverse primer)
  • Multiple exon skipping

Frame 0

LG*AAHCLACSRESLPARPLRARPRTGGREAAK
LLGRGPDLAPGEGAPPKPVGPGTGSHSAQLRGSG
SAEQRGRSGRCPRSRGTRRAAGRALPGAELGLG
PGGRGRAGAGPGGRAALLGSPRRPGRRPLLRAL
FRTCCPRPARSAAAMRLALLWALGLLGAGSPLPS
WPLPNIGGTEEQQAESEKAPREPLEPQVLQDDL
PISLKKVLQTSLPEPLRIKLELDGDSHILELLQ
NRELVPGRPTLVWYQPDGTRVVSEGHTLENCCYQ
GRVRGYAGSWVSICTCSGLRGLVVLTPERSYTL
EQGPGDLQGPPIISRIQDLHLPGHTCALSWRES
VHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIV
ADHSEAQKYRDFQHLLNRTLEVALLLDTFFRPL
NVRVALVGLEAWTQRDLVEISPNPAVTLENFLH
WRRAHLLPRLPHDSAQLVTGTSFSGPTVGMAIQN
SICSPDFSGGVNMDHSTSILGVASSIAHELGHS
LGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLP
GLNFSNCSRRALEKALLDGMGSCLFERLPSLPPM
AAFCGNMFVEPGEQCDCGFLDDCVDPCCDSLTC
QLRPGAQCASDGPCCQNCQLRPSGWQCRPTRGD
CDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCM
HGRCASYAQQCQSLWGPGAQPAAPLCLQTANTR
GNAFGSCGRNPSGSYVSCTPRDAICGQLQCQTG
RTQPLLGSIRDLLWETIDVNGTELNCSWVHLDLG
SDVAQPLLTLPGTACGPGLVCIDHRCQRVDLLG
AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTT
QLKATSSLTTGLLLSLLVLLVLVMLGASYWYRAR
LHQRLCQLKGPTCQYRAAQSGPSERPGPPQRAL
LARGTKASALSFPAPPSRPLPPDPVSKRLQAEL
ADRPNPPTRPLPADPVVRSPK
SQGPAKPPPPRKP
LPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPP
PPTVSSLYL*PLRRFRCLQAGLRASRGGRALWS
PLP*LKAPETGGVLRLRAPPRAVKQHSADLPA*L
QRGLGEGLGVGRD*GRSAQPVSAQLQ*T*HLGS
VPQ

Frame 1

WGEPRTASPAVGKACPPDLSEPGRAQEAGRPRS
Y*GGVRTWRRVKARRPSRSDRAPAPTPHSCGEA
VALSSAGVVGGVPAPEAPGAQRGGLCRGRSLAWG
RVGGGGPGRGLVAARRCWVLRGDLAAGRSSARC
SALAALARPGAPLPCGWRCSGPWGSWARAALCL
PGRSQI*VALRSSRQSQRRPRGSPWSPRSFRTIS
QLASKRCFRPVCLSP*GSSWSWTVTVISWSCYR
IGSWSQAAQPWCGTSPMALGWSVRDTLWRTAAT
REECGDMQAPGCPSAPALGSEAWWS*PQREAIPW
SRGLGTFRVLPLFRESKISTCQATPVP*AGGNL
YTLRSHQSTPWDSATFAGGGMW*QRPRLWSW*L
WLITRRPRNTGTSSTC*TAHWKWPSCWTHSSGP*
MYEWH*WAWRPGPSVTWWRSAQTQLSPSKTSST
GAGHICCLDCPMTVPSW*LVLHSLGLRWAWPFR
TPSVLLTSQEV*TWTTPPASWESPPP*PMSWATA
WAWTMICLGIAAPVQVQPQPRPASWRPPQTSYQ
A*TSATAADGPWRKPSWMEWAAASSNGCLAYPL
WLLSAEICLWSRASSVTVASWMTASIPAVIL*PA
S*GQVHSVHLTDPVVKIASCARLAGSVVLPEGI
VTCLNSAQETAPSVPLMSA*GMASPALAGKLCA
CTGVVPPMPSSASHFGDLEPSPLRHFASRQLILG
EMLLGAVGATPVAVMCPAPLEMPFVGSSSARQV
GPSLCWAPSGIYSGRQ*M*MGLS*TAAGCTWTW
AVMWPSPS*LCLAQPVALAWCV*TIDASVWISWG
HRNVEANAMDMGSVTATGTATVRRAGHPLTAPL
SSKQPAP*PQGCSSASWSYWSW*CLVPATGTVP
ACTSDSASSRDPPASTGQPNLVPLNGQDLRRGPC
WHEALRLVLSASRPPLPGRCRLTLCPRDSRLSW
LTDPIPLPALCPLTRW*EARS
LRGQPSPHPQGS
HCLPTPRAGAHRVTCPAQGLESRP*WYPPDQRHR
LRQCPRSTSDLSGGSAASKPDLGLQEAGVPSGV
PYHD*RRQRLAVS*DSGHRHALSSNTLRTCRRS
CSGGLGRGWGLDGIEEGPHSLSLLSCNKRDILGA
FPR

Frame 2

GVSRALPRLQSGKPARPTSPSQAAHRRQGGREA
TREGSGPGAG*RRAAQAGRTGHRLPLRTVAGKR
*R*AARA*WAVSPLPRHPARSGAGFAGGGAWLG
AGWEGAGRGGAWWPRGAAGFSEATWPPAAPPRAV
PHLLPSPGPERRCHAAGAALGPGAPGRGQPSAF
LAAPKYRWH*GAAGRVREGPEGALGAPGPSGRS
PN*PQKGASDQSA*APEDQVGAGR*QSYPGAATE
*GVGPRPPNPGVVPARWHSGGQ*GTHFGELLLP
GKSAGICRLLGVHLHLLWAQRLGGPDPREKLYP
GAGAWGPSGSSHYFANPRSPPARPHLCPELAGIC
THSEATRAPPGTAPHSPEAGCGNRDQDCGVGDC
G*SLGGPEIPGLPAPAKPHTGSGPLAGHILPAP
ECTSGTSGPGGLDPA*PGGDQPKPSCHPRKLPPL
AQGTFAASIAP*QCPAGDWYFILWAYGGHGHSE
LHLFS*LLRRCEHGPLHQHPGSRLLHSP*VGPQ
PGPGP*FAWE*LPLSRSSPSQDLHHGGLHRLPTR
PELQQLQPTGPGESPPGWNGQLPLRTAA*PTPY
GCFLRKYVCGAGRAV*LWLPG*LRRSLL*FFDL
PAEARCTVCI*RTLLSKLPAAPVWLAVSSYQRGL
*LA*ILPRRQLPVSP*CQPRGWRALRWRASCVH
ARALCLLCPAVPVTLGTWSPARCATLPPDS*YS
GKCFWELWAQPQWQLCVLHP*RCHLWAAPVPDR*
DPASAGLHPGSTLGDNRCEWD*AELQLGAPGPG
Q*CGPAPPDSAWHSLWPWPGVYRPSMPACGSPG
GTGMSKQMPWTWGL*QQQALLL*GGLGTP*LHHS
AQSNQLPDHRAAPQPPGLIGPGDAWCQLLVPCP
PAPATLPAQGTHLPVQGSPIWSL*TARTSAEGP
AGTRH*G*CSQLPGPPFQAAAA*PCVQETPG*AG
*PTQSPYPPSAR*PGGEKPE
VSGASQAPTPKEA
TACRPPGPVPIG*PARPRGWNPAPSGTLQTSAT
ASDSVLALPLTSPEVPLPPSRT*GFKRRACPLES
PTMTEGARDWRCLKTPGTATRCQATLCGPAGVV
AAGAWGGAGGWTGLRKVRTACLCSVAINVTSWE
RSP

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