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Sequences

Sequence NM_001892

CCTTTCCCAGAGTGCTCTGCGCCGTGAAGAAGCGGCTCCCGGGGACTGGGGGCATTTTGTGTTGGCTGGAGCTGGAGTAACAAGATGGCGTCGTCCGCGG AGTGACAGGGGTCCCTCTGGGCCGGAGCCGGCGGCAGTGGTGGCAGCGGTATCGCCGCCCTAGCTCACCGCGCCCCTTTTCCAGCCCGCGACGTCGCCGC GCAAGCGAGGCAGCGGCGGCCGCCGAGAAACAAGTGGCCCAGCCTGGTAACCGCCGAGAAGCCCTTCACAAACTGCGGCCTGGCAAAAAGAAACCTGACT GAGCGGCGGTGATCAGGTTCCCCTCTGCTGATTCTGGGCCCCGAACCCCGGTAAAGGCCTCCGTGTTCCGTTTCCTGCCGCCCTCCTCCGTAGCCTTGCC TAGTGTAGGAGCCCCGAGGCCTCCGTCCTCTTCCCAGAGGTGTCGGGGCTTGGCCCCAGCCTCCATCTTCGTCTCTCAGGATGGCGAGTAGCAGCGGCTC CAAGGCTGAATTCATTGTCGGAGGGAAATATAAACTGGTACGGAAGATCGGGTCTGGCTCCTTCGGGGACATCTATTTGGCGATCAACATCACCAACGGC GAGGAAGTGGCAGTGAAGCTAGAATCTCAGAAGGCCAGGCATCCCCAGTTGCTGTACGAGAGCAAGCTCTATAAGATTCTTCAAGGTGGGGTTGGCATCC CCCACATACGGTGGTATGGTCAGGAAAAAGACTACAATGTACTAGTCATGGATCTTCTGGGACCTAGCCTCGAAGACCTCTTCAATTTCTGTTCAAGAAG GTTCACAATGAAAACTGTACTTATGTTAGCTGACCAGATGATCAGTAGAATTGAATATGTGCATACAAAGAATTTTATACACAGAGACATTAAACCAGAT AACTTCCTAATGGGTATTGGGCGTCACTGTAATAAGTTATTCCTTATTGATTTTGGTTTGGCCAAAAAGTACAGAGACAACAGGACAAGGCAACACATAC CATACAGAGAAGATAAAAACCTCACTGGCACTGCCCGATATGCTAGCATCAATGCACATCTTGGTATTGAGCAGAGTCGCCGAGATGACATGGAATCATT AGGATATGTTTTGATGTATTTTAATAGAACCAGCCTGCCATGGCAAGGGCTAAAGGCTGCAACAAAGAAACAAAAATATGAAAAGATTAGTGAAAAGAAG ATGTCCACGCCTGTTGAAGTTTTATGTAAGGGGTTTCCTGCAGAATTTGCGATGTACTTAAACTATTGTCGTGGGCTACGCTTTGAGGAAGCCCCAGATT ACATGTATCTGAGGCAGCTATTCCGCATTCTTTTCAGGACCCTGAACCATCAATATGACTACACATTTGATTGGACAATGTTAAAGCAGAAAGCAGCACA GCAGGCAGCCTCTTCCAGTGGGCAGGGTCAGCAGGCCCAAACCCCCACAGGCAAGCAAACTGACAAAACCAAGAGTAACATGAAAGGTTTCTAAGCATGA ATTGAGGAACAGAAGAAGCAGAGCAGATGATCGGAGCAGCATTTGTTTCTCCCCAAATCTAGAAATTTTAGTTCATATGTACACTAGCCAGTGGTTGTGG ACAACCATTTACTTGGTGTAAAGAACTTAATTTCAGTATAAACTGACTCTGGGCAGCATTGGTGATGCTGTATCCTGAGTTGTAGCCTCTGTAATTGTGA ATATTAACTGAGATAGTGAAACATGGTGTCCGGTTTTCTATTGCATTTTTTCAAGTGGAAAAGTTAACTAAATGGTTGACACACAAAAATTGGTGGAGAA ATTGTGCATATGCCAATTTTTTGTTAAAACCTTTTGTTTTGAACTATACTGCTTTGAGATCTCATTTCAGAAGAACGGCATGAACAGTCTTCAGCCACAG TTGTGATGGTTGTTAAATGCTCACAATTGTGCATTCTTAGGGTTTTTCCATCCCTGGGGTTTGCAAGTTGTTCACTTAAAACATTCTTAAAATGGTTGGC TTCTTGTCTGCAAGCCAGCTGATATGGTAGCAACCAAAGATTCCAGTGTTTGAGCATATGAAAGACTCTGCCTGCTTAATTGTGCTAGAAATAACAGCAT CTAAAGTGAAGACTTAAGAAAAACTTAGTGACTACTAGATTATCCTTAGGACTCTGCATTAACTCTATAATGTTCTTGGTATTAAAAAAAAAGCATATTT GTCACAGAAATTTAGTTAACATCTTACAACTGAACATGTATGTATGTTGCTTAGATAAATGTAATCACTGTAAACATCTATATGATCTGGGATTTTGTTT TTATTTTGAAATGGGAGCTTTTTTGTTTACAAGTTCATTAAAAACTAAAAACTGTTTCTGTAAGGAAATGAGATTTTTTTTAAACAACAAAAAATGCCTT GCTGACTCACTATTAAATAAAAATCTCCCCAATTTTTTGATAGACTACTTCAAGCCATTTGTTACATGGTATTCCTTTGCAAGTCAATTTAGGTTTCGTG TTATAACTTTTCCTCTTTTTTTAAGAAAAATGAAAAAAGTAATTCTTTTGTCTGAAGGGGAAAGGCATTCTTTCATTTTTTTCTTTTTTTTTTTTTTTTT TTATGACTTGCAGGCACAATATCTAGTACTGCAACTGCCAGAACTTGGTATTGTAGCTGCTGCCCGCTGACTAGCAGCTGGACTGATTTTGAATAAAAAT GAAAGCATTAAAGGGTTTCCCTACAAAACATTTTTCTTTAAAATACTTTTGAAATGGCTATAAGCAGTTGACTTTCACCCTTGGAGAGCATCACACTGTG TGAGGTTCAGTGATTGTTGACCCTCCCCAGCCCCTCCTGCTTCTTTAAGTTATCTGTGTGCGTGCGCTTCCTCTCAATCTTCTTTGCACGCTCATTTCTT TTTCTCTGACCCATGAGAAAGGAAAACTTACTGATGATAATTTTTAAATAGTGTAATTTATTCATTTATAGCATGTCAGGATAAATTAAAAGAACATTTG TCTGGAAATGCTGCCGGGAGCCTATTGTGTAAATGTAGGTATTTTGTAAAATAACCTTGAAATTG

refseq_CSNK1A1.F2 (forward primer)
refseq_CSNK1A1.R2 (reverse primer)
Single exon skipping

Frame 0

PFPECSAP*RSGSRGLGAFCVGWSWSNKMASSA E*QGSLWAGAGGSGGSGIAALAHRAPFPARDVAA QARQRRPPRNKWPSLVTAEKPFTNCGLAKRNLT ERR*SGSPLLILGPEPR*RPPCSVSCRPPP*PC LV*EPRGLRPLPRGVGAWPQPPSSSLRMASSSGS KAEFIVGGKYKLVRKIGSGSFGDIYLAINITNG EEVAVKLESQKARHPQLLYESKLYKILQGGVGI PHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRR FTMKTVLMLADQMISRIEYVHTKNFIHRDIKPD NFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHI PYREDKNLTGTARYASINAHLGIEQSRRDDMESL GYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPD YMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQ QAASSSGQGQQAQTPTGKQTDKTKSNMKGF*A* IEEQKKQSR*SEQHLFLPKSRNFSSYVH*PVVV DNHLLGVKNLISV*TDSGQHW*CCILSCSLCNCE Y*LR**NMVSGFLLHFFKWKS*LNG*HTKIGGE IVHMPIFC*NLLF*TILL*DLISEERHEQSSAT VVMVVKCSQLCILRVFPSLGFASCSLKTFLKWLA SCLQAS*YGSNQRFQCLSI*KTLPA*LC*K*QH LK*RLKKNLVTTRLSLGLCINSIMFLVLKKKHI CHRNLVNILQLNMYVCCLDKCNHCKHLYDLGFCF YFEMGAFLFTSSLKTKNCFCKEMRFFLNNKKCL ADSLLNKNLPNFLIDYFKPFVTWYSFASQFRFR VITFPLFLRKMKKVILLSEGERHSFIFFFFFFFF YDLQAQYLVLQLPELGIVAAAR*LAAGLILNKN ESIKGFPYKTFFFKILLKWL*AVDFHPWRASHC VRFSDC*PSPAPPASLSYLCACASSQSSLHAHFF FSDP*ERKTY***FLNSVIYSFIACQDKLKEHL SGNAAGSLLCKCRYFVK*P*N

Frame 1

LSQSALRREEAAPGDWGHFVLAGAGVTRWRRPR SDRGPSGPEPAAVVAAVSPP*LTAPLFQPATSP RKRGSGGRRETSGPAW*PPRSPSQTAAWQKET*L SGGDQVPLC*FWAPNPGKGLRVPFPAALLRSLA *CRSPEASVLFPEVSGLGPSLHLRLSGWRVAAA PRLNSLSEGNINWYGRSGLAPSGTSIWRSTSPTA RKWQ*S*NLRRPGIPSCCTRASSIRFFKVGLAS PTYGGMVRKKTTMY*SWIFWDLASKTSSISVQE GSQ*KLYLC*LTR*SVELNMCIQRILYTETLNQI TS*WVLGVTVISYSLLILVWPKSTETTGQGNTY HTEKIKTSLALPDMLASMHILVLSRVAEMTWNH *DMF*CILIEPACHGKG*RLQQRNKNMKRLVKRR CPRLLKFYVRGFLQNLRCT*TIVVGYALRKPQI TCI*GSYSAFFSGP*TINMTTHLIGQC*SRKQH SRQPLPVGRVSRPKPPQASKLTKPRVT*KVSKHE LRNRRSRADDRSSICFSPNLEILVHMYTSQWLW TTIYLV*RT*FQYKLTLGSIGDAVS*VVASVIV NIN*DSETWCPVFYCIFSSGKVN*MVDTQKLVEK LCICQFFVKTFCFELYCFEISFQKNGMNSLQPQ L*WLLNAHNCAFLGFFHPWGLQVVHLKHS*NGW LLVCKPADMVATKDSSV*AYERLCLLNCARNNSI *SEDLRKT**LLDYP*DSALTL*CSWY*KKSIF VTEI*LTSYN*TCMYVA*INVITVNIYMIWDFV FILKWELFCLQVH*KLKTVSVRK*DFF*TTKNAL LTHY*IKISPIF**TTSSHLLHGIPLQVNLGFV L*LFLFF*EK*KK*FFCLKGKGILSFFSFFFFF FMTCRHNI*YCNCQNLVL*LLPAD*QLD*F*IKM KALKGFPTKHFSLKYF*NGYKQLTFTLGEHHTV *GSVIVDPPQPLLLL*VICVRALPLNLLCTLIS FSLTHEKGKLTDDNF*IV*FIHL*HVRIN*KNIC LEMLPGAYCVNVGIL*NNLEI

Frame 2

FPRVLCAVKKRLPGTGGILCWLELE*QDGVVRG VTGVPLGRSRRQWWQRYRRPSSPRPFSSPRRRR ASEAAAAAEKQVAQPGNRREALHKLRPGKKKPD *AAVIRFPSADSGPRTPVKASVFRFLPPSSVALP SVGAPRPPSSSQRCRGLAPASIFVSQDGE*QRL QG*IHCRREI*TGTEDRVWLLRGHLFGDQHHQR RGSGSEARISEGQASPVAVREQAL*DSSRWGWHP PHTVVWSGKRLQCTSHGSSGT*PRRPLQFLFKK VHNENCTYVS*PDDQ*N*ICAYKEFYTQRH*TR *LPNGYWASL**VIPY*FWFGQKVQRQQDKATHT IQRR*KPHWHCPIC*HQCTSWY*AESPR*HGII RICFDVF**NQPAMARAKGCNKETKI*KD**KE DVHAC*SFM*GVSCRICDVLKLLSWATL*GSPRL HVSEAAIPHSFQDPEPSI*LHI*LDNVKAESST AGSLFQWAGSAGPNPHRQAN*QNQE*HERFLSM N*GTEEAEQMIGAAFVSPQI*KF*FICTLASGCG QPFTWCKELNFSIN*LWAALVMLYPEL*PL*L* ILTEIVKHGVRFSIAFFQVEKLTKWLTHKNWWR NCAYANFLLKPFVLNYTALRSHFRRTA*TVFSHS CDGC*MLTIVHS*GFSIPGVCKLFT*NILKMVG FLSASQLIW*QPKIPVFEHMKDSACLIVLEITA SKVKT*EKLSDY*IILRTLH*LYNVLGIKKKAYL SQKFS*HLTTEHVCMLLR*M*SL*TSI*SGILF LF*NGSFFVYKFIKN*KLFL*GNEIFFKQQKMP C*LTIK*KSPQFFDRLLQAICYMVFLCKSI*VSC YNFSSFFKKNEKSNSFV*RGKAFFHFFLFFFFF L*LAGTISSTATARTWYCSCCPLTSSWTDFE*K *KH*RVSLQNIFL*NTFEMAISS*LSPLESITLC EVQ*LLTLPSPSCFFKLSVCVRFLSIFFARSFL FL*PMRKENLLMIIFK*CNLFIYSMSG*IKRTF VWKCCREPIV*M*VFCKITLKL

Sequence NM_001025105

CCTTTCCCAGAGTGCTCTGCGCCGTGAAGAAGCGGCTCCCGGGGACTGGGGGCATTTTGTGTTGGCTGGAGCTGGAGTAACAAGATGGCGTCGTCCGCGG AGTGACAGGGGTCCCTCTGGGCCGGAGCCGGCGGCAGTGGTGGCAGCGGTATCGCCGCCCTAGCTCACCGCGCCCCTTTTCCAGCCCGCGACGTCGCCGC GCAAGCGAGGCAGCGGCGGCCGCCGAGAAACAAGTGGCCCAGCCTGGTAACCGCCGAGAAGCCCTTCACAAACTGCGGCCTGGCAAAAAGAAACCTGACT GAGCGGCGGTGATCAGGTTCCCCTCTGCTGATTCTGGGCCCCGAACCCCGGTAAAGGCCTCCGTGTTCCGTTTCCTGCCGCCCTCCTCCGTAGCCTTGCC TAGTGTAGGAGCCCCGAGGCCTCCGTCCTCTTCCCAGAGGTGTCGGGGCTTGGCCCCAGCCTCCATCTTCGTCTCTCAGGATGGCGAGTAGCAGCGGCTC CAAGGCTGAATTCATTGTCGGAGGGAAATATAAACTGGTACGGAAGATCGGGTCTGGCTCCTTCGGGGACATCTATTTGGCGATCAACATCACCAACGGC GAGGAAGTGGCAGTGAAGCTAGAATCTCAGAAGGCCAGGCATCCCCAGTTGCTGTACGAGAGCAAGCTCTATAAGATTCTTCAAGGTGGGGTTGGCATCC CCCACATACGGTGGTATGGTCAGGAAAAAGACTACAATGTACTAGTCATGGATCTTCTGGGACCTAGCCTCGAAGACCTCTTCAATTTCTGTTCAAGAAG GTTCACAATGAAAACTGTACTTATGTTAGCTGACCAGATGATCAGTAGAATTGAATATGTGCATACAAAGAATTTTATACACAGAGACATTAAACCAGAT AACTTCCTAATGGGTATTGGGCGTCACTGTAATAAGTGTTTAGAATCTCCAGTGGGGAAGAGGAAAAGAAGCATGACTGTTAGTACTTCTCAGGACCCAT CTTTCTCAGGATTAAACCAGTTATTCCTTATTGATTTTGGTTTGGCCAAAAAGTACAGAGACAACAGGACAAGGCAACACATACCATACAGAGAAGATAA AAACCTCACTGGCACTGCCCGATATGCTAGCATCAATGCACATCTTGGTATTGAGCAGAGTCGCCGAGATGACATGGAATCATTAGGATATGTTTTGATG TATTTTAATAGAACCAGCCTGCCATGGCAAGGGCTAAAGGCTGCAACAAAGAAACAAAAATATGAAAAGATTAGTGAAAAGAAGATGTCCACGCCTGTTG AAGTTTTATGTAAGGGGTTTCCTGCAGAATTTGCGATGTACTTAAACTATTGTCGTGGGCTACGCTTTGAGGAAGCCCCAGATTACATGTATCTGAGGCA GCTATTCCGCATTCTTTTCAGGACCCTGAACCATCAATATGACTACACATTTGATTGGACAATGTTAAAGCAGAAAGCAGCACAGCAGGCAGCCTCTTCC AGTGGGCAGGGTCAGCAGGCCCAAACCCCCACAGGCAAGCAAACTGACAAAACCAAGAGTAACATGAAAGGTTTCTAAGCATGAATTGAGGAACAGAAGA AGCAGAGCAGATGATCGGAGCAGCATTTGTTTCTCCCCAAATCTAGAAATTTTAGTTCATATGTACACTAGCCAGTGGTTGTGGACAACCATTTACTTGG TGTAAAGAACTTAATTTCAGTATAAACTGACTCTGGGCAGCATTGGTGATGCTGTATCCTGAGTTGTAGCCTCTGTAATTGTGAATATTAACTGAGATAG TGAAACATGGTGTCCGGTTTTCTATTGCATTTTTTCAAGTGGAAAAGTTAACTAAATGGTTGACACACAAAAATTGGTGGAGAAATTGTGCATATGCCAA TTTTTTGTTAAAACCTTTTGTTTTGAACTATACTGCTTTGAGATCTCATTTCAGAAGAACGGCATGAACAGTCTTCAGCCACAGTTGTGATGGTTGTTAA ATGCTCACAATTGTGCATTCTTAGGGTTTTTCCATCCCTGGGGTTTGCAAGTTGTTCACTTAAAACATTCTTAAAATGGTTGGCTTCTTGTCTGCAAGCC AGCTGATATGGTAGCAACCAAAGATTCCAGTGTTTGAGCATATGAAAGACTCTGCCTGCTTAATTGTGCTAGAAATAACAGCATCTAAAGTGAAGACTTA AGAAAAACTTAGTGACTACTAGATTATCCTTAGGACTCTGCATTAACTCTATAATGTTCTTGGTATTAAAAAAAAAGCATATTTGTCACAGAAATTTAGT TAACATCTTACAACTGAACATGTATGTATGTTGCTTAGATAAATGTAATCACTGTAAACATCTATATGATCTGGGATTTTGTTTTTATTTTGAAATGGGA GCTTTTTTGTTTACAAGTTCATTAAAAACTAAAAACTGTTTCTGTAAGGAAATGAGATTTTTTTTAAACAACAAAAAATGCCTTGCTGACTCACTATTAA ATAAAAATCTCCCCAATTTTTTGATAGACTACTTCAAGCCATTTGTTACATGGTATTCCTTTGCAAGTCAATTTAGGTTTCGTGTTATAACTTTTCCTCT TTTTTTAAGAAAAATGAAAAAAGTAATTCTTTTGTCTGAAGGGGAAAGGCATTCTTTCATTTTTTTCTTTTTTTTTTTTTTTTTTTATGACTTGCAGGCA CAATATCTAGTACTGCAACTGCCAGAACTTGGTATTGTAGCTGCTGCCCGCTGACTAGCAGCTGGACTGATTTTGAATAAAAATGAAAGCATTAAAGGGT TTCCCTACAAAACATTTTTCTTTAAAATACTTTTGAAATGGCTATAAGCAGTTGACTTTCACCCTTGGAGAGCATCACACTGTGTGAGGTTCAGTGATTG TTGACCCTCCCCAGCCCCTCCTGCTTCTTTAAGTTATCTGTGTGCGTGCGCTTCCTCTCAATCTTCTTTGCACGCTCATTTCTTTTTCTCTGACCCATGA GAAAGGAAAACTTACTGATGATAATTTTTAAATAGTGTAATTTATTCATTTATAGCATGTCAGGATAAATTAAAAGAACATTTGTCTGGAAATGCTGCCG GGAGCCTATTGTGTAAATGTAGGTATTTTGTAAAATAACCTTGAAATTG

refseq_CSNK1A1.F2 (forward primer)
refseq_CSNK1A1.R2 (reverse primer)
Single exon skipping

Frame 0

PFPECSAP*RSGSRGLGAFCVGWSWSNKMASSA E*QGSLWAGAGGSGGSGIAALAHRAPFPARDVAA QARQRRPPRNKWPSLVTAEKPFTNCGLAKRNLT ERR*SGSPLLILGPEPR*RPPCSVSCRPPP*PC LV*EPRGLRPLPRGVGAWPQPPSSSLRMASSSGS KAEFIVGGKYKLVRKIGSGSFGDIYLAINITNG EEVAVKLESQKARHPQLLYESKLYKILQGGVGI PHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRR FTMKTVLMLADQMISRIEYVHTKNFIHRDIKPD NFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDP SFSGLNQLFLIDFGLAKKYRDNRTRQHIPYREDK NLTGTARYASINAHLGIEQSRRDDMESLGYVLM YFNRTSLPWQGLKAATKKQKYEKISEKKMSTPV EVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQ LFRILFRTLNHQYDYTFDWTMLKQKAAQQAASS SGQGQQAQTPTGKQTDKTKSNMKGF*A*IEEQK KQSR*SEQHLFLPKSRNFSSYVH*PVVVDNHLLG VKNLISV*TDSGQHW*CCILSCSLCNCEY*LR* *NMVSGFLLHFFKWKS*LNG*HTKIGGEIVHMP IFC*NLLF*TILL*DLISEERHEQSSATVVMVVK CSQLCILRVFPSLGFASCSLKTFLKWLASCLQA S*YGSNQRFQCLSI*KTLPA*LC*K*QHLK*RL KKNLVTTRLSLGLCINSIMFLVLKKKHICHRNLV NILQLNMYVCCLDKCNHCKHLYDLGFCFYFEMG AFLFTSSLKTKNCFCKEMRFFLNNKKCLADSLL NKNLPNFLIDYFKPFVTWYSFASQFRFRVITFPL FLRKMKKVILLSEGERHSFIFFFFFFFFYDLQA QYLVLQLPELGIVAAAR*LAAGLILNKNESIKG FPYKTFFFKILLKWL*AVDFHPWRASHCVRFSDC *PSPAPPASLSYLCACASSQSSLHAHFFFSDP* ERKTY***FLNSVIYSFIACQDKLKEHLSGNAA GSLLCKCRYFVK*P*N

Frame 1

LSQSALRREEAAPGDWGHFVLAGAGVTRWRRPR SDRGPSGPEPAAVVAAVSPP*LTAPLFQPATSP RKRGSGGRRETSGPAW*PPRSPSQTAAWQKET*L SGGDQVPLC*FWAPNPGKGLRVPFPAALLRSLA *CRSPEASVLFPEVSGLGPSLHLRLSGWRVAAA PRLNSLSEGNINWYGRSGLAPSGTSIWRSTSPTA RKWQ*S*NLRRPGIPSCCTRASSIRFFKVGLAS PTYGGMVRKKTTMY*SWIFWDLASKTSSISVQE GSQ*KLYLC*LTR*SVELNMCIQRILYTETLNQI TS*WVLGVTVISV*NLQWGRGKEA*LLVLLRTH LSQD*TSYSLLILVWPKSTETTGQGNTYHTEKI KTSLALPDMLASMHILVLSRVAEMTWNH*DMF*C ILIEPACHGKG*RLQQRNKNMKRLVKRRCPRLL KFYVRGFLQNLRCT*TIVVGYALRKPQITCI*G SYSAFFSGP*TINMTTHLIGQC*SRKQHSRQPLP VGRVSRPKPPQASKLTKPRVT*KVSKHELRNRR SRADDRSSICFSPNLEILVHMYTSQWLWTTIYL V*RT*FQYKLTLGSIGDAVS*VVASVIVNIN*DS ETWCPVFYCIFSSGKVN*MVDTQKLVEKLCICQ FFVKTFCFELYCFEISFQKNGMNSLQPQL*WLL NAHNCAFLGFFHPWGLQVVHLKHS*NGWLLVCKP ADMVATKDSSV*AYERLCLLNCARNNSI*SEDL RKT**LLDYP*DSALTL*CSWY*KKSIFVTEI* LTSYN*TCMYVA*INVITVNIYMIWDFVFILKWE LFCLQVH*KLKTVSVRK*DFF*TTKNALLTHY* IKISPIF**TTSSHLLHGIPLQVNLGFVL*LFL FF*EK*KK*FFCLKGKGILSFFSFFFFFFMTCRH NI*YCNCQNLVL*LLPAD*QLD*F*IKMKALKG FPTKHFSLKYF*NGYKQLTFTLGEHHTV*GSVI VDPPQPLLLL*VICVRALPLNLLCTLISFSLTHE KGKLTDDNF*IV*FIHL*HVRIN*KNICLEMLP GAYCVNVGIL*NNLEI

Frame 2

FPRVLCAVKKRLPGTGGILCWLELE*QDGVVRG VTGVPLGRSRRQWWQRYRRPSSPRPFSSPRRRR ASEAAAAAEKQVAQPGNRREALHKLRPGKKKPD *AAVIRFPSADSGPRTPVKASVFRFLPPSSVALP SVGAPRPPSSSQRCRGLAPASIFVSQDGE*QRL QG*IHCRREI*TGTEDRVWLLRGHLFGDQHHQR RGSGSEARISEGQASPVAVREQAL*DSSRWGWHP PHTVVWSGKRLQCTSHGSSGT*PRRPLQFLFKK VHNENCTYVS*PDDQ*N*ICAYKEFYTQRH*TR *LPNGYWASL**VFRISSGEEEKKHDC*YFSGPI FLRIKPVIPY*FWFGQKVQRQQDKATHTIQRR* KPHWHCPIC*HQCTSWY*AESPR*HGIIRICFD VF**NQPAMARAKGCNKETKI*KD**KEDVHAC* SFM*GVSCRICDVLKLLSWATL*GSPRLHVSEA AIPHSFQDPEPSI*LHI*LDNVKAESSTAGSLF QWAGSAGPNPHRQAN*QNQE*HERFLSMN*GTEE AEQMIGAAFVSPQI*KF*FICTLASGCGQPFTW CKELNFSIN*LWAALVMLYPEL*PL*L*ILTEI VKHGVRFSIAFFQVEKLTKWLTHKNWWRNCAYAN FLLKPFVLNYTALRSHFRRTA*TVFSHSCDGC* MLTIVHS*GFSIPGVCKLFT*NILKMVGFLSAS QLIW*QPKIPVFEHMKDSACLIVLEITASKVKT* EKLSDY*IILRTLH*LYNVLGIKKKAYLSQKFS *HLTTEHVCMLLR*M*SL*TSI*SGILFLF*NG SFFVYKFIKN*KLFL*GNEIFFKQQKMPC*LTIK *KSPQFFDRLLQAICYMVFLCKSI*VSCYNFSS FFKKNEKSNSFV*RGKAFFHFFLFFFFFL*LAG TISSTATARTWYCSCCPLTSSWTDFE*K*KH*RV SLQNIFL*NTFEMAISS*LSPLESITLCEVQ*L LTLPSPSCFFKLSVCVRFLSIFFARSFLFL*PM RKENLLMIIFK*CNLFIYSMSG*IKRTFVWKCCR EPIV*M*VFCKITLKL