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Sequences

Sequence NM_001684

TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAGATCGTCCAAA
GCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAGCTCTCCTGCACCCTTTTTCT
TTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTAGCCAGAAAGGCAAGAGAGCAAAGCCAGCGT
CTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATCCATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTG
GATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGCTCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCT
AAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACCTTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATC
ACCACCTGGGGACACCAATCATCGTGACACGGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAG
GATCTAGACTTCGGACGGCTACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTT
GAGACAGGGAGGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGCGTTCAAGGGA
TGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGAT
CTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGC
TTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCC
AGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGC
AAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGA
TTGTGGTTGGTGATATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCT
GACAGGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACA
GCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAG
TCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAA
GAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCT
CTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACT
TTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAA
AATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATG
AACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCA
ATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCT
GCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGC
AAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGG
ACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTG
CATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGAC
CCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCA
TTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGA
GCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACT
GTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGGCATCGCAG
GCACAGATGTAGCAAAGGAGGCTTCAGACATCATCCTAACAGATGACAACTTCACCAGCATTGTGAAGGCAGTGATGTGGGGACGAAATGTCTATGACAG
CATCTCCAAGTTCCTGCAGTTCCAGCTCACTGTCAATGTGGTGGCCGTGATTGTAGCCTTCACTGGAGCCTGTATCACTCAGGATTCCCCATTGAAAGCT
GTGCAGATGTTGTGGGTTAATCTGATCATGGACACTTTTGCTTCATTGGCCCTGGCCACAGAGCCCCCTACGGAATCTCTGTTGAAGCGGCGCCCCTATG
GCCGAAATAAGCCTCTGATCTCACGCACTATGATGAAGAACATCTTGGGCCATGCATTCTATCAGCTCATTGTCATCTTTATCCTTGTCTTTGCGGGTGA
GAAATTCTTTGATATTGATAGTGGGAGGAAGGCACCTCTACATTCACCACCCAGCCAGCACTATACCATTGTTTTTAACACCTTCGTGCTGATGCAGCTC
TTCAATGAAATCAACTCCCGAAAGATCCATGGAGAGAAGAACGTCTTTTCAGGCATCTACCGCAACATTATCTTCTGCTCTGTAGTCTTGGGCACATTCA
TCTGCCAGATTTTCATCGTGGAATTTGGGGGTAAACCCTTCAGTTGTACAAGCCTCAGCCTGTCTCAGTGGCTGTGGTGTCTCTTCATTGGGATTGGAGA
ACTTCTGTGGGGCCAGTTCATCTCCGCAATACCTACCCGATCCCTGAAGTTCCTGAAGGAGGCTGGGCATGGCACCACCAAAGAGGAGATCACCAAGGAT
GCCGAGGGACTGGATGAGATTGACCATGCTGAGATGGAGCTGCGCCGAGGCCAGATCCTCTGGTTCCGGGGCCTGAACCGTATCCAGACTCAGATCAAAG
TGGTCAAAGCGTTCC
ATAGTTCCCTCCACGAAAGCATTCAGAAACCCTACAACCAAAAGTCCATCCACAGCTTCATGACCCACCCTGAATTCGCCATAGA
GGAGGAGTTGCCACGAACACCACTCCTGGATGAGGAAGAGGAGGAAAATCCTGACAAGGCTTCTAAGTTTGGGACTAGGGTGCTCCTGTTGGATGGTGAG
GTCACTCCATATGCCAATACAAACAACAATGCGGTGGATTGCAACCAAGTGCAGCTCCCCCAGTCGGACAGCTCTCTACAGAGCCTAGAGACATCAGTTT
GAATTTTCTTTCTCTGACTCTCATCCCTATTTTACCTATTTCCATTTTCGTCTATCCCATCTATGAGGTGATGATGGGACTTTTCATTGTCACGTCAGCT
GCTGTGTTAACAGCAGTGTGTGTGAAGTGAACCTCTACCTGACCATGAAGAGGCAAGAGCACAGACTTACAAGGATTTCAACTTAAGCTTGACTTGGGGT
TTGTAGCGGGACCCAGTCAAACCCCATTCAGGTCATGGTAGAATCTACTCCTTGGTAGTCACTTGTCATTTTTAAAGAAATGATGACAATCCTCTTGGCA
TCACCCCACCCCACATTCTCCCCGATGTTCCTCTCCTGAATTCTGGATTTTGTCCTACAAGTCTGTGCCATTTATAAGCTAAGTTGAGGGTTCAGAGGGA
GACAAATATCCCCAAGTGAAATATGTTGCGGTAGAGATGGAATGTATAAAATCCGCCAGTAGTGTGATTGTTTTTCAATTTTTCCCACTTTGAAAACTTA
CACCTAAAGGCCTGTAGGCCTCTAACTCTTTCTGCCCTTTCATTCAAACCTCTCCAAAGTTCTTTGTCTTTTGTCTTCCCTTCCTTTCCTTTTTTTTTTT
TTTTTTTATGATGATTAAGAAAATGGAAAGGATATGGATGAATTGTGTAAACTTAGATCCTTCTCCCTTTTGGCCCAAAAGAACCCTTGATTTAGTTCCA
GAATCCAACCAGTTTCTTTGTTAAAAGGGTCCTTTTGAAGCAATTAAGTGCTGGTAAGAATATTTCTCTGTTGTTGCCAGGTTACCTTCTGCTTTTAAAT
TGCCATCTTGTAAAGTGTATGTGGTTCTTAAGTGCCAGGGAGATCAGCCTTGCCCATGAAGGTTGCATATGTGTGGTATACAGTTTTTACCTGAAAGCCT
GAGCTTTCTCTTATTCCTAAAGTGGTGGCAAAAGAATGAACTGGGTATGACCCTGCCCCCTTACTGGGCTTGGATATTGAGGACCAGACGCTGCCAAATC
TAGGACAAGACAGACCATCAAAGCAGACTTTTGTGGGCTCCTCTTTGGGGTGACCACTGCTTTCAAAGCCATCTGCCAAGGCTCTCCAGGGCAGGACCTG
ACTGGTGGGGAATGAGTGTTCAGAAGCCTTGGGAGAGGCCAAAGAGCCATTCTAGCATGATCTGAGAAAACCTTCCTGCAGAGGCCAGAAACCTTGAGCT
TAGGTGCCTGGGGACCAGCTTCGACATTCTCTCCAGTTTCTGATTCTAATTTTTGCCACGTGTCACAACTTTTCCAGTCTCTGAGAAGGTCCCAGCCTTT
CTCAAATATTCTGATTTTGAAAATATGTATCCAAAGTGGGAGGCCCCTGTGACATTTTGCCAACTTAAACGAGAAAAAGACCCCCCGCACCCGGCACACT
CCCCCTTCCTCCAGCCCCGCTTCAGCCACATGCTCCAGCTGCTGCCCAGTAAAGCCCTGTGCCTTTTTTTCCCCTGAATACTGCCCAAAGCATCCCCTTC
CCATCTGCCTCTCAGGAGTTGGGGACTTTGCTAGGAGATTTTTTAAGTGTTCCTTACTGGGACAACGTGGAGCCACGTTTGCAGGAGCTCCATTTGTATC
CCTGCTGGTGTTGACTTCTGTGTAGGGGCCAGTTCATGTCCCTGACTCTCACCTCCCATTAGATAAATGAAGCCCACCCCCCTTTCTAGAGTGATGAGAG
TCAAGAAGAGGGGATGTATGAACGGCCAAATTCCCATGTGAGAGGAAGATGACCTGATCCACCTAGCCTTTTCTTCTGGATCTGTCCTCCCTCACCCCTT
TCACCTGAGCTGTCCACAGTAGGAAACATAAAGAAACAATGTCCCCTACATATCCCCATGACTACATAATCCATCATCGTAGGAAATAGGAAAGCAAATT
TGATTTTGGTTTTGTAAAACGTACATGCTTCAATAATTCTTTTTTGTGTCTTAAATACTCATAGGGGAAAAAAACAGCTCACCCAAGGTGTTAGGTTTCA
CATATATATTCATCAACTATTTTAGAAGATTTAATTCTATCAAATCTTGTATTACCTCAGATCATTTTAAATAGCAAGCCAATAACGAGCTTTGAAGGCT
ATTTTACCATTCCTGTTCACAAAAGGTTCTCATGGTGCCTGACAGGTTACCCTTGAGGGCTTGTGTCTACTTTTTAAAAGTCAATGGTTTTTTTTCTTGT
GTTCTAGTTTCCATAATAGGAGAGAAAATATAGAAATATATGCAAAAATTATAGTTTTCTTTAGATCAGAAACTGATATTTTTGGGTCAGCCATATGTAT
TTTGTTTAAAGGATTTAAAATAAAGTGCCGTCATGTAGCCCTGTGGAAGGGAGCACATAACCAGCTGTTTGGCATGACAGGTGACTTAGTATATTTGTAA
TTGGTTTTAAAACCAATACACCATACTTTCTTTCTGCAAACAGCCATCTTTATACTTAGGGAAGAAAAATTGTTGGGTTCTAGACTTTTTTAATATAAAT
TTTGTTGATATGGAATTAGGTAAGTTTAAGTGTCTATGTGCATATGTTTTTTATATAAGTTTTTTCTATTCAGTTTCACTGATCCAACTGGCAGTGGGTA
AATATGGCATAAGTTAATAACACTTTTCCCCAAAATGGTGCTTTGGATTTGAAAAGGGTCTGATGGGGAGAAGGAGAACGTATCATCCTAGCTTCCTCTC
TTAATAAACCTAGAAAAACGGGTAGTAAACTGTGGATAGTCAGGAAAACACCCAGCAAGGGACACAGCTGTCAGGAAATGAATCTTCCCCCCAACCCCCA
CCATGCAGATGGATAGACAGAATCTTTCCTGACTAGTCATTAGGATCAGGGGCCTCTGTTGGATTTGTGTTTCTTGAAGAATAGCTGGCAGAGTGGTATA
AAAGACACGAATATCTCCTGGTCTATAAGGATACTCTGATTTGGGGTTTGCATTTTTCATGGTTTTTATTTCCTGTTCCCCCTGGAGTTTTCCATTAGTG
AGTTTTTGTGCAAGGATCTTATTTGTGATGCCTTCCCTCCCCTAGAAAGATTTTGTGCAATATATTAAATGGGGACAGAATTCTAAATGGATAAAACAAT
GGCTGGTTCTAGCCCTGAGTGACAGTCTTAAGGCTAGATCCTTCCCATAGTATCATCTGTCCTCTGGAATGACTCTCCTGTCCCTAAAGGGGTTAAGAGA
GAGATCACCTAGAAATCCCTCTGGACACTTGTGGGTTCTTTAGGGTTTGAGTTTCTTCTTCCCCTTGAGCTTCAGAGAGGAGAGTTGGCATGGTTAAATC
TGAATGGTTACCTCACTGCTGAAAACCCAGAGGGGCGTGGCACACTCGCTTGTGTGGAAAAGCCTCTAAATGCATCCCTTCCTTTCTTTCCTGCTTCCTT
TGCCTTACAATTGAAGCAGCCCGTGGTACCATCACAGTATGCAGAGACTTCCTCACCTTTCATATCTAGGGACCACCCCCGATGCATTGGTGAGGGTGGG
CACTTATAAATGCCTGCTATTGTTAAGCCATTCCAGCCTCTTCCTCTGAATAGACCAGACGCCCTTTCACTTAGTTCAGTGCCAGTCCTTTTGCCTTCCC
AACCCTGCTGTTAGGCCTGCTGTTCCCTTTGCTCTTGATTAGGAGAGATGGAAGGAGATGAGCTCCCATAACTGAATTGGCCTTTGGTTCATGTTTTCTC
CCCATATGTATATATGCCATATGTGAATATGCCATATATATGTGCCAACAAATCTATCTACGTTGTTCTTTTCAAATTAGCACGCAGATAGGAATTTTGA
GTTTCTTCTTCTTTTAGTAACTAGTATAACAAGCACTGGTATTTTTGTACAAAAAAGAAAAACAAAAGATTGACTATTGTGGTCTGCATGACATAAACAA
ACAAATGGTGATATCAAAGCAACGTATACCCCAGTCCAGTGTGTGTTGCCATAATTTGCAATTCAGCTTAACAGTGCACCCAATCTATATTTGCATTTTG
ATATTATTTAAGCTCTATGTACAAGGTTTTGCATGTATTTATATGGTTCTTAGGGAAAAAAAATGCTATAAACTGCAAATCTGAAATTCAAATGTGTTGT
TCCACTGAGACCAGAAGAAGAAGAGGAGTTTTAAAAGGGATAATTTGTTGGAGCCAATAAAGCTTTTTGCTGATGAACAGAAACCAATACTGCTGTGCAC
TGAGAATAAAAACTCATGCCCACTTGTAA
  • refseq_ATP2B4.F1 (forward primer)
  • refseq_ATP2B4.R1 (reverse primer)
  • Single exon skipping

Frame 0

LGRAGEQESGPS*LELLP*QAFS*ESSAVEIVQ
SWGLGGGARTSWGTIPPKRARSETPAQLSCTLFL
SGT*EVLPIGGAGGGDPAHSPALARKAREQSQR
L*LGCHTGETGGWSPHPTLIHGNPEGESRLKKP
GSLLERERSSCHRYPGSSPLPPPDVYYYSCWLLL
RLLPW*HAHPVYTFIWASWSKLGTYLPWTTTII
TTWGHQSS*HGVHLPLSSPILFLLSLPDFIRKK
GSRLRTATRELIAQDIFNLFPHWAPREARSRKKL
RQGGRRHWSVEGKRYIFSG*GAW*QQAK*RTHQ
TVSCLPTRWPRAVKGTLAAQ*WN*GSSWSCVQG
MH*PRLMSTMEVYRISAVD*KPPLWKVCLGTLQI
WRNVGRCLDTT*SPPKSPRLS*N*CGKLFKMSR
LSSWRLQPSSPWSCPFIALLVKKMNCVVKSQLP
QKMKMRHKLAGLRGQPSFSQ*SSWC**LPLMIGA
KRSNSGGCSAALNRSKSSPSSETVNSSSSLWLR
LWLVILPKSNTVICCLQMES*SKGMI*RLMRAL
*QGNLTMSRSPWTKTPCCSQGPMSWKVLAGWW*Q
LLVSTLRLESSLLSWGSMRMTKGRKRRKVKNKE
SLKIATKQRPKTEWPWKSSHSTARRESTMRKRT
RRQSRCLKRRSQCCRAS*LAWLFRLGKPVCSCLL
SRFSS*FYTL*LTTL**IADHGSLSVLPSTSST
LSSSSSSASLYWWWLCQRGCLWLSPSHWPTL*R
K**KTIT*YGTWMLVRPWATPPPSALIRQAR*P*
TA*LWYKLILGASITVKSQALMSSCPKSWTSLS
MAFLSTVLIPPRFCLQRRREACLGRWATRPSVL
C*ALSQI*SRIIRLCVMKCPRRSSTRCTPLTQCA
SQ*APSSGIPTVASVCTARAPLRSSCASVIESW
TGKGKQCHSRIKTEMIWYALSSSPWPVMDSGLS
A*LTGTSMTQSPLGTMRMRSSPN*PVSRWWALRT
LCAQRCQMLLPNANKLALLSEW*QVTTSTQPGP
LPPNVAF*HLGMTSCA*KAKNSTGSSATRKAR*
SKKSWTRSGLSFGSWRDLLPLTSTPW*KA*LTAL
LGNTGRSWLSLVMAQMTGLL*RKRMLVLPWASQ
AQM*QRRLQTSS*QMTTSPAL*RQ*CGDEMSMT
ASPSSCSSSSLSMWWP*L*PSLEPVSLRIPH*KL
CRCCGLI*SWTLLLHWPWPQSPLRNLC*SGAPM
AEISL*SHAL**RTSWAMHSISSLSSLSLSLRV
RNSLILIVGGRHLYIHHPASTIPLFLTPSC*CSS
SMKSTPERSMERRTSFQASTATLSSAL*SWAHS
SARFSSWNLGVNPSVVQASACLSGCGVSSLGLE
NFCGASSSPQYLPDP*SS*RRLGMAPPKRRSPRM
PRDWMRLTMLRWSCAEARSSGSGA*TVSRLRSK
WSKRS
IVPSTKAFRNPTTKSPSTAS*PTLNSP*
RRSCHEHHSWMRKRRKILTRLLSLGLGCSCWMVR
SLHMPIQTTMRWIATKCSSPSRTALYRA*RHQF
EFSFSDSHPYFTYFHFRLSHL*GDDGTFHCHVS
CCVNSSVCEVNLYLTMKRQEHRLTRIST*A*LGV
CSGTQSNPIQVMVESTPW*SLVIFKEMMTILLA
SPHPTFSPMFLS*ILDFVLQVCAIYKLS*GFRG
RQISPSEICCGRDGMYKIRQ*CDCFSIFPTLKTY
T*RPVGL*LFLPFHSNLSKVLCLLSSLPFLFFF
FFYDD*ENGKDMDELCKLRSFSLLAQKNP*FSS
RIQPVSLLKGSF*SN*VLVRIFLCCCQVTFCF*I
AIL*SVCGS*VPGRSALPMKVAYVWYTVFT*KP
ELSLIPKVVAKE*TGYDPAPLLGLDIEDQTLPN
LGQDRPSKQTFVGSSLG*PLLSKPSAKALQGRT*
LVGNECSEALGEAKEPF*HDLRKPSCRGQKP*A
*VPGDQLRHSLQFLILIFATCHNFSSL*EGPSL
SQIF*F*KYVSKVGGPCDILPT*TRKRPPAPGTL
PLPPAPLQPHAPAAAQ*SPVPFFPLNTAQSIPF
PSASQELGTLLGDFLSVPYWDNVEPRLQELHLY
PCWC*LLCRGQFMSLTLTSH*INEAHPPF*SDES
QEEGMYERPNSHVRGR*PDPPSLFFWICPPSPL
SPELSTVGNIKKQCPLHIPMTT*SIIVGNRKAN
LILVL*NVHASIILFCVLNTHRGKKQLTQGVRFH
IYIHQLF*KI*FYQILYYLRSF*IASQ*RALKA
ILPFLFTKGSHGA*QVTLEGLCLLFKSQWFFFL
CSSFHNRRENIEIYAKIIVFFRSETDIFGSAICI
LFKGFKIKCRHVALWKGAHNQLFGMTGDLVYL*
LVLKPIHHTFFLQTAIFILREEKLLGSRLF*YK
FC*YGIR*V*VSMCICFLYKFFLFSFTDPTGSG*
IWHKLITLFPKMVLWI*KGSDGEKENVSS*LPL
LINLEKRVVNCG*SGKHPARDTAVRK*IFPPTP
TMQMDRQNLS*LVIRIRGLCWICVS*RIAGRVV*
KTRISPGL*GYSDLGFAFFMVFISCSPWSFPLV
SFCARILFVMPSLP*KDFVQYIKWGQNSKWIKQ
WLVLALSDSLKARSFP*YHLSSGMTLLSLKGLRE
RSPRNPSGHLWVL*GLSFFFPLSFREESWHG*I
*MVTSLLKTQRGVAHSLVWKSL*MHPFLSFLLP
LPYN*SSPWYHHSMQRLPHLSYLGTTPDALVRVG
TYKCLLLLSHSSLFL*IDQTPFHLVQCQSFCLP
NPAVRPAVPFALD*ERWKEMSSHN*IGLWFMFS
PHMYICHM*ICHIYVPTNLSTLFFSN*HADRNFE
FLLLLVTSITSTGIFVQKRKTKD*LLWSA*HKQ
TNGDIKATYTPVQCVLP*FAIQLNSAPNLYLHF
DII*ALCTRFCMYLYGS*GKKML*TANLKFKCVV
PLRPEEEEEF*KG*FVGANKAFC**TETNTAVH
*E*KLMPTC

Frame 1

WGELVSKSLARVS*SCCHDKHFLKKALLLRSSK
AGGWEGGHELRGAPSLRREQDQRHPPSSPAPFF
FQEPERSFPLEGQGEETQPTPRP*PERQESKASV
SSLVATLGRLVGGHPTLPSSMETRRESPA*RNL
DLC*KERDPVVIGIQEALLFLLLTSTTTVAGCC
*GCCHGNMHILFTPSSGQVGLS*EPTYPGQLLSS
PPGDTNHRDTESTFHSVPPSSSSSRCQTSYGRK
DLDFGRLLGSLLHKIYSIYSLTGPPEKQEVGRS
*DREAGDTGQLKGNATSSLVEGLGNSRQNDEPIR
PCLACQLDGREP*RGLWLHSNGTEEAHGAAFKG
CTDPD*CPLWRCTESLQ*TENLPCGRSVWEPCR
SGET*AGVWTQRDPPQKAQDFLRISVGSSSRCHA
YHPGDCSHHLPGPVLLSPCW*RK*TVWSSRNYP
RR*K*GTSWLD*GGSHPFLSDHRGVSDCL**LE
QREAIPGAAVPH*TGAKVLHHPKRSTHPAPCG*D
CGW*YCPSQIR*SAACRWNPDPRE*SED**ELS
DRGI*PCQEVPGQRPHVALRDPCHGRFWPDGGD
SCWCQLSDWNHPYSLGGQ*G*RRGEKEER*KTRS
P*KSQQSKDPRRSGPGNPATQQPGGNRQ*GKGQ
EGSQGA*KGEVSAAGQADSPGCSDWESRSAHVC
SHGFHPDSILCD*QLCDKSQTMAP*VYSHLHPVL
CQVLHHRHHCTGGGCARGAASGCHHLTGLLCEE
NDERQ*PSTALGCL*DHGQRHRHLL**DRHVDH
EPHDCGTSLYWGHPLPSNPKP*CLPAQSPGPHCQ
WHFYQQCLYLQDSASREGGRPASAGGQQDRVCS
ARLCHRSEAGLSGCA**SARGEALQGVHL*LSA
QVNEHRHQESQRWLPYVQQGRL*DHLAQV*SNPG
PERGSSAIQE*RQR*YGTHCHRAHGL*WTPDYL
HSLPGLR*HRALLGQ*E*DPHRTDLYRGGGH*G
PCAPRGARCYCQMQTSWHYCQNGDR*QHQHSPGH
CHQMWHSDTWG*LPVLRRQRIQPAHPQRERRGR
ARKAGQDLA*ASGPGAIFSH*QAHPGERHN*QH
CWGTPAGRGCHW*WHK*RACSEESGCWFCHGHRR
HRCSKGGFRHHPNR*QLHQHCEGSDVGTKCL*Q
HLQVPAVPAHCQCGGRDCSLHWSLYHSGFPIES
CADVVG*SDHGHFCFIGPGHRAPYGISVEAAPLW
PK*ASDLTHYDEEHLGPCILSAHCHLYPCLCG*
EIL*Y**WEEGTSTFTTQPALYHCF*HLRADAA
LQ*NQLPKDPWREERLFRHLPQHYLLLCSLGHIH
LPDFHRGIWG*TLQLYKPQPVSVAVVSLHWDWR
TSVGPVHLRNTYPIPEVPEGGWAWHHQRGDHQG
CRGTG*D*PC*DGAAPRPDPLVPGPEPYPDSDQS
GQSVP
*FPPRKHSETLQPKVHPQLHDPP*IRHR
GGVATNTTPG*GRGGKS*QGF*VWD*GAPVGW*
GHSICQYKQQCGGLQPSAAPPVGQLSTEPRDISL
NFLSLTLIPILPISIFVYPIYEVMMGLFIVTSA
AVLTAVCVK*TST*P*RGKSTDLQGFQLKLDLG
FVAGPSQTPFRSW*NLLLGSHLSFLKK**QSSWH
HPTPHSPRCSSPEFWILSYKSVPFIS*VEGSEG
DKYPQVKYVAVEMECIKSASSVIVFQFFPL*KL
TPKGL*ASNSFCPFIQTSPKFFVFCLPFLSFFFF
FFMMIKKMERIWMNCVNLDPSPFWPKRTLDLVP
ESNQFLC*KGPFEAIKCW*EYFSVVARLPSAFK
LPSCKVYVVLKCQGDQPCP*RLHMCGIQFLPESL
SFLLFLKWWQKNELGMTLPPYWAWILRTRRCQI
*DKTDHQSRLLWAPLWGDHCFQSHLPRLSRAGP
DWWGMSVQKPWERPKSHSSMI*ENLPAEARNLEL
RCLGTSFDILSSF*F*FLPRVTTFPVSEKVPAF
LKYSDFENMYPKWEAPVTFCQLKREKDPPHPAH
SPFLQPRFSHMLQLLPSKALCLFFP*ILPKASPS
HLPLRSWGLC*EIF*VFLTGTTWSHVCRSSICI
PAGVDFCVGASSCP*LSPPIR*MKPTPLSRVMR
VKKRGCMNGQIPM*EEDDLIHLAFSSGSVLPHPF
HLSCPQ*ET*RNNVPYISP*LHNPSS*EIGKQI
*FWFCKTYMLQ*FFFVS*ILIGEKNSSPKVLGF
TYIFINYFRRFNSIKSCITSDHFK*QANNEL*RL
FYHSCSQKVLMVPDRLPLRACVYFLKVNGFFSC
VLVSIIGEKI*KYMQKL*FSLDQKLIFLGQPYV
FCLKDLK*SAVM*PCGREHITSCLA*QVT*YICN
WF*NQYTILSFCKQPSLYLGKKNCWVLDFFNIN
FVDMELGKFKCLCAYVFYISFFYSVSLIQLAVG
KYGIS**HFSPKWCFGFEKGLMGRRRTYHPSFLS
**T*KNG**TVDSQENTQQGTQLSGNESSPQPP
PCRWIDRIFPD*SLGSGASVGFVFLEE*LAEWY
KRHEYLLVYKDTLIWGLHFSWFLFPVPPGVFH**
VFVQGSYL*CLPSPRKILCNILNGDRILNG*NN
GWF*P*VTVLRLDPSHSIICPLE*LSCP*RG*E
RDHLEIPLDTCGFFRV*VSSSP*ASERRVGMVKS
EWLPHC*KPRGAWHTRLCGKASKCIPSFLSCFL
CLTIEAARGTITVCRDFLTFHI*GPPPMHW*GW
ALINACYC*AIPASSSE*TRRPFT*FSASPFAFP
TLLLGLLFPLLLIRRDGRR*APITELAFGSCFL
PICIYAICEYAIYMCQQIYLRCSFQISTQIGIL
SFFFF**LV*QALVFLYKKEKQKIDYCGLHDINK
QMVISKQRIPQSSVCCHNLQFSLTVHPIYICIL
ILFKLYVQGFACIYMVLREKKCYKLQI*NSNVL
FH*DQKKKRSFKRDNLLEPIKLFADEQKPILLCT
ENKNSCPLV

Frame 2

GESW*ARVWPELARAVAMTSIFLRKLCC*DRPK
LGAGRGGTNFVGHHPSEESKIRDTRPALLHPFS
FRNLRGPSHWRGRGRRPSPLPGLSQKGKRAKPA
SLAWLPHWGDWWVVTPPYPHPWKPGGRVPPEETW
IFARKREIQLSSVSRKLSSSSS*RLLLQLLVVA
KVAAMVTCTSCLHLHLGKLV*ARNLPTLDNYYH
HHLGTPIIVTRSPPSTQFPHPLPPLAARLHTEER
I*TSDGYSGAYCTRYIQSIPSLGPQRSKK*EEV
ETGRQETLVS*RETLHLLWLRGLVTAGKMTNPS
DRVLPANSMAESREGDFGCTVMELRKLMELRSRD
ALTQINVHYGGVQNLCSRLKTSPVEGLSGNPAD
LEKRRQVFGHNVIPPKKPKTFLELVWEALQDVT
LIILEIAAIISLVLSFYRPAGEENELCGQVATTP
EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWS
KEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAE
IVVGDIAQVKYGDLLPADGILIQGNDLKIDESSL
TGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVT
AVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQG
VPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDK
KAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSA
LTVFILILYFVIDNFVINRRPWLPECTPIYIQY
FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKK
MMKDNNLVRHLDACETMGNATAICSDKTGTLTM
NRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIV
NGISINSAYTSKILPPEKEGGLPRQVGNKTECAL
LGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVR
KSMSTVIRNPNGGFRMYSKGASEIILRKCNRIL
DRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTIC
IAYRDFDDTEPSWDNENEILTELTCIAVVGIED
PVRPEVPDAIAKCKQAGITVRMVTGDNINTARA
IATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVE
QEKLDKIWPKLRVLARSSPTDKHTLVKGIIDST
VGEHRQVVAVTGDGTNDGPALKKADVGFAMGIA
GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDS
ISKFLQFQLTVNVVAVIVAFTGACITQDSPLKA
VQMLWVNLIMDTFASLALATEPPTESLLKRRPY
GRNKPLISRTMMKNILGHAFYQLIVIFILVFAGE
KFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQL
FNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTF
ICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGE
LLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD
AEGLDEIDHAEMELRRGQILWFRGLNRIQTQIK
VVKAF
HSSLHESIQKPYNQKSIHSFMTHPEFAIE
EELPRTPLLDEEEEENPDKASKFGTRVLLLDGE
VTPYANTNNNAVDCNQVQLPQSDSSLQSLETSV
*IFFL*LSSLFYLFPFSSIPSMR**WDFSLSRQL
LC*QQCV*SEPLPDHEEARAQTYKDFNLSLTWG
L*RDPVKPHSGHGRIYSLVVTCHF*RNDDNPLG
ITPPHILPDVPLLNSGFCPTSLCHL*AKLRVQRE
TNIPK*NMLR*RWNV*NPPVV*LFFNFSHFENL
HLKACRPLTLSALSFKPLQSSLSFVFPSFPFFF
FFL**LRKWKGYG*IV*T*ILLPFGPKEPLI*FQ
NPTSFFVKRVLLKQLSAGKNISLLLPGYLLLLN
CHLVKCMWFLSAREISLAHEGCICVVYSFYLKA
*AFSYS*SGGKRMNWV*PCPLTGLGY*GPDAAKS
RTRQTIKADFCGLLFGVTTAFKAICQGSPGQDL
TGGE*VFRSLGRGQRAILA*SEKTFLQRPETLS
LGAWGPASTFSPVSDSNFCHVSQLFQSLRRSQPF
SNILILKICIQSGRPL*HFANLNEKKTPRTRHT
PPSSSPASATCSSCCPVKPCAFFSPEYCPKHPL
PICLSGVGDFARRFFKCSLLGQRGATFAGAPFVS
LLVLTSV*GPVHVPDSHLPLDK*SPPPFLE**E
SRRGDV*TAKFPCERKMT*ST*PFLLDLSSLTP
FT*AVHSRKHKETMSPTYPHDYIIHHRRK*ESKF
DFGFVKRTCFNNSFLCLKYS*GKKTAHPRC*VS
HIYSSTILEDLILSNLVLPQIILNSKPITSFEG
YFTIPVHKRFSWCLTGYP*GLVSTF*KSMVFFLV
F*FP**ERKYRNICKNYSFL*IRN*YFWVSHMY
FV*RI*NKVPSCSPVEGST*PAVWHDR*LSIFV
IGFKTNTPYFLSANSHLYT*GRKIVGF*TFLI*I
LLIWN*VSLSVYVHMFFI*VFSIQFH*SNWQWV
NMA*VNNTFPQNGALDLKRV*WGEGERIILASS
LNKPRKTGSKLWIVRKTPSKGHSCQEMNLPPNPH
HADG*TESFLTSH*DQGPLLDLCFLKNSWQSGI
KDTNISWSIRIL*FGVCIFHGFYFLFPLEFSIS
EFLCKDLICDAFPPLERFCAIY*MGTEF*MDKTM
AGSSPE*QS*G*ILPIVSSVLWNDSPVPKGVKR
EIT*KSLWTLVGSLGFEFLLPLELQRGELAWLN
LNGYLTAENPEGRGTLACVEKPLNASLPFFPASF
ALQLKQPVVPSQYAETSSPFISRDHPRCIGEGG
HL*MPAIVKPFQPLPLNRPDALSLSSVPVLLPS
QPCC*ACCSLCS*LGEMEGDELP*LNWPLVHVFS
PYVYMPYVNMPYICANKSIYVVLFKLARR*EF*
VSSSFSN*YNKHWYFCTKKKNKRLTIVVCMT*T
NKW*YQSNVYPSPVCVAIICNSA*QCTQSIFAF*
YYLSSMYKVLHVFIWFLGKKNAINCKSEIQMCC
STETRRRRGVLKGIICWSQ*SFLLMNRNQYCCA
LRIKTHAHL*

Sequence NM_001001396

TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAGATCGTCCAAA
GCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAGCTCTCCTGCACCCTTTTTCT
TTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTAGCCAGAAAGGCAAGAGAGCAAAGCCAGCGT
CTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATCCATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTG
GATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGCTCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCT
AAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACCTTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATC
ACCACCTGGGGACACCAATCATCGTGACACGGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAG
GATCTAGACTTCGGACGGCTACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTT
GAGACAGGGAGGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGCGTTCAAGGGA
TGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGAT
CTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGC
TTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCC
AGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGC
AAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGA
TTGTGGTTGGTGATATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCT
GACAGGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACA
GCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAG
TCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAA
GAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCT
CTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACT
TTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAA
AATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATG
AACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCA
ATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCT
GCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGC
AAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGG
ACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTG
CATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGAC
CCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCA
TTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGA
GCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACT
GTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGGCATCGCAG
GCACAGATGTAGCAAAGGAGGCTTCAGACATCATCCTAACAGATGACAACTTCACCAGCATTGTGAAGGCAGTGATGTGGGGACGAAATGTCTATGACAG
CATCTCCAAGTTCCTGCAGTTCCAGCTCACTGTCAATGTGGTGGCCGTGATTGTAGCCTTCACTGGAGCCTGTATCACTCAGGATTCCCCATTGAAAGCT
GTGCAGATGTTGTGGGTTAATCTGATCATGGACACTTTTGCTTCATTGGCCCTGGCCACAGAGCCCCCTACGGAATCTCTGTTGAAGCGGCGCCCCTATG
GCCGAAATAAGCCTCTGATCTCACGCACTATGATGAAGAACATCTTGGGCCATGCATTCTATCAGCTCATTGTCATCTTTATCCTTGTCTTTGCGGGTGA
GAAATTCTTTGATATTGATAGTGGGAGGAAGGCACCTCTACATTCACCACCCAGCCAGCACTATACCATTGTTTTTAACACCTTCGTGCTGATGCAGCTC
TTCAATGAAATCAACTCCCGAAAGATCCATGGAGAGAAGAACGTCTTTTCAGGCATCTACCGCAACATTATCTTCTGCTCTGTAGTCTTGGGCACATTCA
TCTGCCAGATTTTCATCGTGGAATTTGGGGGTAAACCCTTCAGTTGTACAAGCCTCAGCCTGTCTCAGTGGCTGTGGTGTCTCTTCATTGGGATTGGAGA
ACTTCTGTGGGGCCAGTTCATCTCCGCAATACCTACCCGATCCCTGAAGTTCCTGAAGGAGGCTGGGCATGGCACCACCAAAGAGGAGATCACCAAGGAT
GCCGAGGGACTGGATGAGATTGACCATGCTGAGATGGAGCTGCGCCGAGGCCAGATCCTCTGGTTCCGGGGCCTGAACCGTATCCAGACTCAGATCGACG
TAATTAACACATTCCAGACGGGAGCCTCTTTTAAGGGAGTCCTAAGGCGACAGAACATGGGTCAACACCTTGATGTAAAACTTGTTCCTAGTTCATCCTA
TGTAGCAGTTGCACCAGTCAAATCTTCCCCCACCACTTCTGTTCCTGCTGTTTCATCTCCTCCTATGGGCA
ATCAAAGTGGTCAAAGCGTTCCATAGTTC
CCTCCACGAAAGCATTCAGAAACCCTACAACCAAAAGTCCATCCACAGCTTCATGACCCACCCTGAATTCGCCATAGAGGAGGAGTTGCCACGAACACCA
CTCCTGGATGAGGAAGAGGAGGAAAATCCTGACAAGGCTTCTAAGTTTGGGACTAGGGTGCTCCTGTTGGATGGTGAGGTCACTCCATATGCCAATACAA
ACAACAATGCGGTGGATTGCAACCAAGTGCAGCTCCCCCAGTCGGACAGCTCTCTACAGAGCCTAGAGACATCAGTTTGAATTTTCTTTCTCTGACTCTC
ATCCCTATTTTACCTATTTCCATTTTCGTCTATCCCATCTATGAGGTGATGATGGGACTTTTCATTGTCACGTCAGCTGCTGTGTTAACAGCAGTGTGTG
TGAAGTGAACCTCTACCTGACCATGAAGAGGCAAGAGCACAGACTTACAAGGATTTCAACTTAAGCTTGACTTGGGGTTTGTAGCGGGACCCAGTCAAAC
CCCATTCAGGTCATGGTAGAATCTACTCCTTGGTAGTCACTTGTCATTTTTAAAGAAATGATGACAATCCTCTTGGCATCACCCCACCCCACATTCTCCC
CGATGTTCCTCTCCTGAATTCTGGATTTTGTCCTACAAGTCTGTGCCATTTATAAGCTAAGTTGAGGGTTCAGAGGGAGACAAATATCCCCAAGTGAAAT
ATGTTGCGGTAGAGATGGAATGTATAAAATCCGCCAGTAGTGTGATTGTTTTTCAATTTTTCCCACTTTGAAAACTTACACCTAAAGGCCTGTAGGCCTC
TAACTCTTTCTGCCCTTTCATTCAAACCTCTCCAAAGTTCTTTGTCTTTTGTCTTCCCTTCCTTTCCTTTTTTTTTTTTTTTTTTATGATGATTAAGAAA
ATGGAAAGGATATGGATGAATTGTGTAAACTTAGATCCTTCTCCCTTTTGGCCCAAAAGAACCCTTGATTTAGTTCCAGAATCCAACCAGTTTCTTTGTT
AAAAGGGTCCTTTTGAAGCAATTAAGTGCTGGTAAGAATATTTCTCTGTTGTTGCCAGGTTACCTTCTGCTTTTAAATTGCCATCTTGTAAAGTGTATGT
GGTTCTTAAGTGCCAGGGAGATCAGCCTTGCCCATGAAGGTTGCATATGTGTGGTATACAGTTTTTACCTGAAAGCCTGAGCTTTCTCTTATTCCTAAAG
TGGTGGCAAAAGAATGAACTGGGTATGACCCTGCCCCCTTACTGGGCTTGGATATTGAGGACCAGACGCTGCCAAATCTAGGACAAGACAGACCATCAAA
GCAGACTTTTGTGGGCTCCTCTTTGGGGTGACCACTGCTTTCAAAGCCATCTGCCAAGGCTCTCCAGGGCAGGACCTGACTGGTGGGGAATGAGTGTTCA
GAAGCCTTGGGAGAGGCCAAAGAGCCATTCTAGCATGATCTGAGAAAACCTTCCTGCAGAGGCCAGAAACCTTGAGCTTAGGTGCCTGGGGACCAGCTTC
GACATTCTCTCCAGTTTCTGATTCTAATTTTTGCCACGTGTCACAACTTTTCCAGTCTCTGAGAAGGTCCCAGCCTTTCTCAAATATTCTGATTTTGAAA
ATATGTATCCAAAGTGGGAGGCCCCTGTGACATTTTGCCAACTTAAACGAGAAAAAGACCCCCCGCACCCGGCACACTCCCCCTTCCTCCAGCCCCGCTT
CAGCCACATGCTCCAGCTGCTGCCCAGTAAAGCCCTGTGCCTTTTTTTCCCCTGAATACTGCCCAAAGCATCCCCTTCCCATCTGCCTCTCAGGAGTTGG
GGACTTTGCTAGGAGATTTTTTAAGTGTTCCTTACTGGGACAACGTGGAGCCACGTTTGCAGGAGCTCCATTTGTATCCCTGCTGGTGTTGACTTCTGTG
TAGGGGCCAGTTCATGTCCCTGACTCTCACCTCCCATTAGATAAATGAAGCCCACCCCCCTTTCTAGAGTGATGAGAGTCAAGAAGAGGGGATGTATGAA
CGGCCAAATTCCCATGTGAGAGGAAGATGACCTGATCCACCTAGCCTTTTCTTCTGGATCTGTCCTCCCTCACCCCTTTCACCTGAGCTGTCCACAGTAG
GAAACATAAAGAAACAATGTCCCCTACATATCCCCATGACTACATAATCCATCATCGTAGGAAATAGGAAAGCAAATTTGATTTTGGTTTTGTAAAACGT
ACATGCTTCAATAATTCTTTTTTGTGTCTTAAATACTCATAGGGGAAAAAAACAGCTCACCCAAGGTGTTAGGTTTCACATATATATTCATCAACTATTT
TAGAAGATTTAATTCTATCAAATCTTGTATTACCTCAGATCATTTTAAATAGCAAGCCAATAACGAGCTTTGAAGGCTATTTTACCATTCCTGTTCACAA
AAGGTTCTCATGGTGCCTGACAGGTTACCCTTGAGGGCTTGTGTCTACTTTTTAAAAGTCAATGGTTTTTTTTCTTGTGTTCTAGTTTCCATAATAGGAG
AGAAAATATAGAAATATATGCAAAAATTATAGTTTTCTTTAGATCAGAAACTGATATTTTTGGGTCAGCCATATGTATTTTGTTTAAAGGATTTAAAATA
AAGTGCCGTCATGTAGCCCTGTGGAAGGGAGCACATAACCAGCTGTTTGGCATGACAGGTGACTTAGTATATTTGTAATTGGTTTTAAAACCAATACACC
ATACTTTCTTTCTGCAAACAGCCATCTTTATACTTAGGGAAGAAAAATTGTTGGGTTCTAGACTTTTTTAATATAAATTTTGTTGATATGGAATTAGGTA
AGTTTAAGTGTCTATGTGCATATGTTTTTTATATAAGTTTTTTCTATTCAGTTTCACTGATCCAACTGGCAGTGGGTAAATATGGCATAAGTTAATAACA
CTTTTCCCCAAAATGGTGCTTTGGATTTGAAAAGGGTCTGATGGGGAGAAGGAGAACGTATCATCCTAGCTTCCTCTCTTAATAAACCTAGAAAAACGGG
TAGTAAACTGTGGATAGTCAGGAAAACACCCAGCAAGGGACACAGCTGTCAGGAAATGAATCTTCCCCCCAACCCCCACCATGCAGATGGATAGACAGAA
TCTTTCCTGACTAGTCATTAGGATCAGGGGCCTCTGTTGGATTTGTGTTTCTTGAAGAATAGCTGGCAGAGTGGTATAAAAGACACGAATATCTCCTGGT
CTATAAGGATACTCTGATTTGGGGTTTGCATTTTTCATGGTTTTTATTTCCTGTTCCCCCTGGAGTTTTCCATTAGTGAGTTTTTGTGCAAGGATCTTAT
TTGTGATGCCTTCCCTCCCCTAGAAAGATTTTGTGCAATATATTAAATGGGGACAGAATTCTAAATGGATAAAACAATGGCTGGTTCTAGCCCTGAGTGA
CAGTCTTAAGGCTAGATCCTTCCCATAGTATCATCTGTCCTCTGGAATGACTCTCCTGTCCCTAAAGGGGTTAAGAGAGAGATCACCTAGAAATCCCTCT
GGACACTTGTGGGTTCTTTAGGGTTTGAGTTTCTTCTTCCCCTTGAGCTTCAGAGAGGAGAGTTGGCATGGTTAAATCTGAATGGTTACCTCACTGCTGA
AAACCCAGAGGGGCGTGGCACACTCGCTTGTGTGGAAAAGCCTCTAAATGCATCCCTTCCTTTCTTTCCTGCTTCCTTTGCCTTACAATTGAAGCAGCCC
GTGGTACCATCACAGTATGCAGAGACTTCCTCACCTTTCATATCTAGGGACCACCCCCGATGCATTGGTGAGGGTGGGCACTTATAAATGCCTGCTATTG
TTAAGCCATTCCAGCCTCTTCCTCTGAATAGACCAGACGCCCTTTCACTTAGTTCAGTGCCAGTCCTTTTGCCTTCCCAACCCTGCTGTTAGGCCTGCTG
TTCCCTTTGCTCTTGATTAGGAGAGATGGAAGGAGATGAGCTCCCATAACTGAATTGGCCTTTGGTTCATGTTTTCTCCCCATATGTATATATGCCATAT
GTGAATATGCCATATATATGTGCCAACAAATCTATCTACGTTGTTCTTTTCAAATTAGCACGCAGATAGGAATTTTGAGTTTCTTCTTCTTTTAGTAACT
AGTATAACAAGCACTGGTATTTTTGTACAAAAAAGAAAAACAAAAGATTGACTATTGTGGTCTGCATGACATAAACAAACAAATGGTGATATCAAAGCAA
CGTATACCCCAGTCCAGTGTGTGTTGCCATAATTTGCAATTCAGCTTAACAGTGCACCCAATCTATATTTGCATTTTGATATTATTTAAGCTCTATGTAC
AAGGTTTTGCATGTATTTATATGGTTCTTAGGGAAAAAAAATGCTATAAACTGCAAATCTGAAATTCAAATGTGTTGTTCCACTGAGACCAGAAGAAGAA
GAGGAGTTTTAAAAGGGATAATTTGTTGGAGCCAATAAAGCTTTTTGCTGATGAACAGAAACCAATACTGCTGTGCACTGAGAATAAAAACTCATGCCCA
CTTGTAA
  • refseq_ATP2B4.F1 (forward primer)
  • refseq_ATP2B4.R1 (reverse primer)
  • Single exon skipping

Frame 0

LGRAGEQESGPS*LELLP*QAFS*ESSAVEIVQ
SWGLGGGARTSWGTIPPKRARSETPAQLSCTLFL
SGT*EVLPIGGAGGGDPAHSPALARKAREQSQR
L*LGCHTGETGGWSPHPTLIHGNPEGESRLKKP
GSLLERERSSCHRYPGSSPLPPPDVYYYSCWLLL
RLLPW*HAHPVYTFIWASWSKLGTYLPWTTTII
TTWGHQSS*HGVHLPLSSPILFLLSLPDFIRKK
GSRLRTATRELIAQDIFNLFPHWAPREARSRKKL
RQGGRRHWSVEGKRYIFSG*GAW*QQAK*RTHQ
TVSCLPTRWPRAVKGTLAAQ*WN*GSSWSCVQG
MH*PRLMSTMEVYRISAVD*KPPLWKVCLGTLQI
WRNVGRCLDTT*SPPKSPRLS*N*CGKLFKMSR
LSSWRLQPSSPWSCPFIALLVKKMNCVVKSQLP
QKMKMRHKLAGLRGQPSFSQ*SSWC**LPLMIGA
KRSNSGGCSAALNRSKSSPSSETVNSSSSLWLR
LWLVILPKSNTVICCLQMES*SKGMI*RLMRAL
*QGNLTMSRSPWTKTPCCSQGPMSWKVLAGWW*Q
LLVSTLRLESSLLSWGSMRMTKGRKRRKVKNKE
SLKIATKQRPKTEWPWKSSHSTARRESTMRKRT
RRQSRCLKRRSQCCRAS*LAWLFRLGKPVCSCLL
SRFSS*FYTL*LTTL**IADHGSLSVLPSTSST
LSSSSSSASLYWWWLCQRGCLWLSPSHWPTL*R
K**KTIT*YGTWMLVRPWATPPPSALIRQAR*P*
TA*LWYKLILGASITVKSQALMSSCPKSWTSLS
MAFLSTVLIPPRFCLQRRREACLGRWATRPSVL
C*ALSQI*SRIIRLCVMKCPRRSSTRCTPLTQCA
SQ*APSSGIPTVASVCTARAPLRSSCASVIESW
TGKGKQCHSRIKTEMIWYALSSSPWPVMDSGLS
A*LTGTSMTQSPLGTMRMRSSPN*PVSRWWALRT
LCAQRCQMLLPNANKLALLSEW*QVTTSTQPGP
LPPNVAF*HLGMTSCA*KAKNSTGSSATRKAR*
SKKSWTRSGLSFGSWRDLLPLTSTPW*KA*LTAL
LGNTGRSWLSLVMAQMTGLL*RKRMLVLPWASQ
AQM*QRRLQTSS*QMTTSPAL*RQ*CGDEMSMT
ASPSSCSSSSLSMWWP*L*PSLEPVSLRIPH*KL
CRCCGLI*SWTLLLHWPWPQSPLRNLC*SGAPM
AEISL*SHAL**RTSWAMHSISSLSSLSLSLRV
RNSLILIVGGRHLYIHHPASTIPLFLTPSC*CSS
SMKSTPERSMERRTSFQASTATLSSAL*SWAHS
SARFSSWNLGVNPSVVQASACLSGCGVSSLGLE
NFCGASSSPQYLPDP*SS*RRLGMAPPKRRSPRM
PRDWMRLTMLRWSCAEARSSGSGA*TVSRLRST
*LTHSRREPLLRES*GDRTWVNTLM*NLFLVHP
M*QLHQSNLPPPLLFLLFHLLLWA
IKVVKAFHSS
LHESIQKPYNQKSIHSFMTHPEFAIEEELPRTP
LLDEEEEENPDKASKFGTRVLLLDGEVTPYANT
NNNAVDCNQVQLPQSDSSLQSLETSV*IFFL*LS
SLFYLFPFSSIPSMR**WDFSLSRQLLC*QQCV
*SEPLPDHEEARAQTYKDFNLSLTWGL*RDPVK
PHSGHGRIYSLVVTCHF*RNDDNPLGITPPHILP
DVPLLNSGFCPTSLCHL*AKLRVQRETNIPK*N
MLR*RWNV*NPPVV*LFFNFSHFENLHLKACRP
LTLSALSFKPLQSSLSFVFPSFPFFFFFL**LRK
WKGYG*IV*T*ILLPFGPKEPLI*FQNPTSFFV
KRVLLKQLSAGKNISLLLPGYLLLLNCHLVKCM
WFLSAREISLAHEGCICVVYSFYLKA*AFSYS*S
GGKRMNWV*PCPLTGLGY*GPDAAKSRTRQTIK
ADFCGLLFGVTTAFKAICQGSPGQDLTGGE*VF
RSLGRGQRAILA*SEKTFLQRPETLSLGAWGPAS
TFSPVSDSNFCHVSQLFQSLRRSQPFSNILILK
ICIQSGRPL*HFANLNEKKTPRTRHTPPSSSPA
SATCSSCCPVKPCAFFSPEYCPKHPLPICLSGVG
DFARRFFKCSLLGQRGATFAGAPFVSLLVLTSV
*GPVHVPDSHLPLDK*SPPPFLE**ESRRGDV*
TAKFPCERKMT*ST*PFLLDLSSLTPFT*AVHSR
KHKETMSPTYPHDYIIHHRRK*ESKFDFGFVKR
TCFNNSFLCLKYS*GKKTAHPRC*VSHIYSSTI
LEDLILSNLVLPQIILNSKPITSFEGYFTIPVHK
RFSWCLTGYP*GLVSTF*KSMVFFLVF*FP**E
RKYRNICKNYSFL*IRN*YFWVSHMYFV*RI*N
KVPSCSPVEGST*PAVWHDR*LSIFVIGFKTNTP
YFLSANSHLYT*GRKIVGF*TFLI*ILLIWN*V
SLSVYVHMFFI*VFSIQFH*SNWQWVNMA*VNN
TFPQNGALDLKRV*WGEGERIILASSLNKPRKTG
SKLWIVRKTPSKGHSCQEMNLPPNPHHADG*TE
SFLTSH*DQGPLLDLCFLKNSWQSGIKDTNISW
SIRIL*FGVCIFHGFYFLFPLEFSISEFLCKDLI
CDAFPPLERFCAIY*MGTEF*MDKTMAGSSPE*
QS*G*ILPIVSSVLWNDSPVPKGVKREIT*KSL
WTLVGSLGFEFLLPLELQRGELAWLNLNGYLTAE
NPEGRGTLACVEKPLNASLPFFPASFALQLKQP
VVPSQYAETSSPFISRDHPRCIGEGGHL*MPAI
VKPFQPLPLNRPDALSLSSVPVLLPSQPCC*ACC
SLCS*LGEMEGDELP*LNWPLVHVFSPYVYMPY
VNMPYICANKSIYVVLFKLARR*EF*VSSSFSN
*YNKHWYFCTKKKNKRLTIVVCMT*TNKW*YQSN
VYPSPVCVAIICNSA*QCTQSIFAF*YYLSSMY
KVLHVFIWFLGKKNAINCKSEIQMCCSTETRRR
RGVLKGIICWSQ*SFLLMNRNQYCCALRIKTHAH
L*

Frame 1

WGELVSKSLARVS*SCCHDKHFLKKALLLRSSK
AGGWEGGHELRGAPSLRREQDQRHPPSSPAPFF
FQEPERSFPLEGQGEETQPTPRP*PERQESKASV
SSLVATLGRLVGGHPTLPSSMETRRESPA*RNL
DLC*KERDPVVIGIQEALLFLLLTSTTTVAGCC
*GCCHGNMHILFTPSSGQVGLS*EPTYPGQLLSS
PPGDTNHRDTESTFHSVPPSSSSSRCQTSYGRK
DLDFGRLLGSLLHKIYSIYSLTGPPEKQEVGRS
*DREAGDTGQLKGNATSSLVEGLGNSRQNDEPIR
PCLACQLDGREP*RGLWLHSNGTEEAHGAAFKG
CTDPD*CPLWRCTESLQ*TENLPCGRSVWEPCR
SGET*AGVWTQRDPPQKAQDFLRISVGSSSRCHA
YHPGDCSHHLPGPVLLSPCW*RK*TVWSSRNYP
RR*K*GTSWLD*GGSHPFLSDHRGVSDCL**LE
QREAIPGAAVPH*TGAKVLHHPKRSTHPAPCG*D
CGW*YCPSQIR*SAACRWNPDPRE*SED**ELS
DRGI*PCQEVPGQRPHVALRDPCHGRFWPDGGD
SCWCQLSDWNHPYSLGGQ*G*RRGEKEER*KTRS
P*KSQQSKDPRRSGPGNPATQQPGGNRQ*GKGQ
EGSQGA*KGEVSAAGQADSPGCSDWESRSAHVC
SHGFHPDSILCD*QLCDKSQTMAP*VYSHLHPVL
CQVLHHRHHCTGGGCARGAASGCHHLTGLLCEE
NDERQ*PSTALGCL*DHGQRHRHLL**DRHVDH
EPHDCGTSLYWGHPLPSNPKP*CLPAQSPGPHCQ
WHFYQQCLYLQDSASREGGRPASAGGQQDRVCS
ARLCHRSEAGLSGCA**SARGEALQGVHL*LSA
QVNEHRHQESQRWLPYVQQGRL*DHLAQV*SNPG
PERGSSAIQE*RQR*YGTHCHRAHGL*WTPDYL
HSLPGLR*HRALLGQ*E*DPHRTDLYRGGGH*G
PCAPRGARCYCQMQTSWHYCQNGDR*QHQHSPGH
CHQMWHSDTWG*LPVLRRQRIQPAHPQRERRGR
ARKAGQDLA*ASGPGAIFSH*QAHPGERHN*QH
CWGTPAGRGCHW*WHK*RACSEESGCWFCHGHRR
HRCSKGGFRHHPNR*QLHQHCEGSDVGTKCL*Q
HLQVPAVPAHCQCGGRDCSLHWSLYHSGFPIES
CADVVG*SDHGHFCFIGPGHRAPYGISVEAAPLW
PK*ASDLTHYDEEHLGPCILSAHCHLYPCLCG*
EIL*Y**WEEGTSTFTTQPALYHCF*HLRADAA
LQ*NQLPKDPWREERLFRHLPQHYLLLCSLGHIH
LPDFHRGIWG*TLQLYKPQPVSVAVVSLHWDWR
TSVGPVHLRNTYPIPEVPEGGWAWHHQRGDHQG
CRGTG*D*PC*DGAAPRPDPLVPGPEPYPDSDRR
N*HIPDGSLF*GSPKATEHGSTP*CKTCS*FIL
CSSCTSQIFPHHFCSCCFISSYGQ
SKWSKRSIV
PSTKAFRNPTTKSPSTAS*PTLNSP*RRSCHEHH
SWMRKRRKILTRLLSLGLGCSCWMVRSLHMPIQ
TTMRWIATKCSSPSRTALYRA*RHQFEFSFSDS
HPYFTYFHFRLSHL*GDDGTFHCHVSCCVNSSVC
EVNLYLTMKRQEHRLTRIST*A*LGVCSGTQSN
PIQVMVESTPW*SLVIFKEMMTILLASPHPTFS
PMFLS*ILDFVLQVCAIYKLS*GFRGRQISPSEI
CCGRDGMYKIRQ*CDCFSIFPTLKTYT*RPVGL
*LFLPFHSNLSKVLCLLSSLPFLFFFFFYDD*E
NGKDMDELCKLRSFSLLAQKNP*FSSRIQPVSLL
KGSF*SN*VLVRIFLCCCQVTFCF*IAIL*SVC
GS*VPGRSALPMKVAYVWYTVFT*KPELSLIPK
VVAKE*TGYDPAPLLGLDIEDQTLPNLGQDRPSK
QTFVGSSLG*PLLSKPSAKALQGRT*LVGNECS
EALGEAKEPF*HDLRKPSCRGQKP*A*VPGDQL
RHSLQFLILIFATCHNFSSL*EGPSLSQIF*F*K
YVSKVGGPCDILPT*TRKRPPAPGTLPLPPAPL
QPHAPAAAQ*SPVPFFPLNTAQSIPFPSASQEL
GTLLGDFLSVPYWDNVEPRLQELHLYPCWC*LLC
RGQFMSLTLTSH*INEAHPPF*SDESQEEGMYE
RPNSHVRGR*PDPPSLFFWICPPSPLSPELSTV
GNIKKQCPLHIPMTT*SIIVGNRKANLILVL*NV
HASIILFCVLNTHRGKKQLTQGVRFHIYIHQLF
*KI*FYQILYYLRSF*IASQ*RALKAILPFLFT
KGSHGA*QVTLEGLCLLFKSQWFFFLCSSFHNRR
ENIEIYAKIIVFFRSETDIFGSAICILFKGFKI
KCRHVALWKGAHNQLFGMTGDLVYL*LVLKPIH
HTFFLQTAIFILREEKLLGSRLF*YKFC*YGIR*
V*VSMCICFLYKFFLFSFTDPTGSG*IWHKLIT
LFPKMVLWI*KGSDGEKENVSS*LPLLINLEKR
VVNCG*SGKHPARDTAVRK*IFPPTPTMQMDRQN
LS*LVIRIRGLCWICVS*RIAGRVV*KTRISPG
L*GYSDLGFAFFMVFISCSPWSFPLVSFCARIL
FVMPSLP*KDFVQYIKWGQNSKWIKQWLVLALSD
SLKARSFP*YHLSSGMTLLSLKGLRERSPRNPS
GHLWVL*GLSFFFPLSFREESWHG*I*MVTSLL
KTQRGVAHSLVWKSL*MHPFLSFLLPLPYN*SSP
WYHHSMQRLPHLSYLGTTPDALVRVGTYKCLLL
LSHSSLFL*IDQTPFHLVQCQSFCLPNPAVRPA
VPFALD*ERWKEMSSHN*IGLWFMFSPHMYICHM
*ICHIYVPTNLSTLFFSN*HADRNFEFLLLLVT
SITSTGIFVQKRKTKD*LLWSA*HKQTNGDIKA
TYTPVQCVLP*FAIQLNSAPNLYLHFDII*ALCT
RFCMYLYGS*GKKML*TANLKFKCVVPLRPEEE
EEF*KG*FVGANKAFC**TETNTAVH*E*KLMP
TC

Frame 2

GESW*ARVWPELARAVAMTSIFLRKLCC*DRPK
LGAGRGGTNFVGHHPSEESKIRDTRPALLHPFS
FRNLRGPSHWRGRGRRPSPLPGLSQKGKRAKPA
SLAWLPHWGDWWVVTPPYPHPWKPGGRVPPEETW
IFARKREIQLSSVSRKLSSSSS*RLLLQLLVVA
KVAAMVTCTSCLHLHLGKLV*ARNLPTLDNYYH
HHLGTPIIVTRSPPSTQFPHPLPPLAARLHTEER
I*TSDGYSGAYCTRYIQSIPSLGPQRSKK*EEV
ETGRQETLVS*RETLHLLWLRGLVTAGKMTNPS
DRVLPANSMAESREGDFGCTVMELRKLMELRSRD
ALTQINVHYGGVQNLCSRLKTSPVEGLSGNPAD
LEKRRQVFGHNVIPPKKPKTFLELVWEALQDVT
LIILEIAAIISLVLSFYRPAGEENELCGQVATTP
EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWS
KEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAE
IVVGDIAQVKYGDLLPADGILIQGNDLKIDESSL
TGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVT
AVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQG
VPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDK
KAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSA
LTVFILILYFVIDNFVINRRPWLPECTPIYIQY
FVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKK
MMKDNNLVRHLDACETMGNATAICSDKTGTLTM
NRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIV
NGISINSAYTSKILPPEKEGGLPRQVGNKTECAL
LGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVR
KSMSTVIRNPNGGFRMYSKGASEIILRKCNRIL
DRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTIC
IAYRDFDDTEPSWDNENEILTELTCIAVVGIED
PVRPEVPDAIAKCKQAGITVRMVTGDNINTARA
IATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVE
QEKLDKIWPKLRVLARSSPTDKHTLVKGIIDST
VGEHRQVVAVTGDGTNDGPALKKADVGFAMGIA
GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDS
ISKFLQFQLTVNVVAVIVAFTGACITQDSPLKA
VQMLWVNLIMDTFASLALATEPPTESLLKRRPY
GRNKPLISRTMMKNILGHAFYQLIVIFILVFAGE
KFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQL
FNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTF
ICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGE
LLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD
AEGLDEIDHAEMELRRGQILWFRGLNRIQTQID
VINTFQTGASFKGVLRRQNMGQHLDVKLVPSSSY
VAVAPVKSSPTTSVPAVSSPPMG
NQSGQSVP*F
PPRKHSETLQPKVHPQLHDPP*IRHRGGVATNT
TPG*GRGGKS*QGF*VWD*GAPVGW*GHSICQYK
QQCGGLQPSAAPPVGQLSTEPRDISLNFLSLTL
IPILPISIFVYPIYEVMMGLFIVTSAAVLTAVC
VK*TST*P*RGKSTDLQGFQLKLDLGFVAGPSQT
PFRSW*NLLLGSHLSFLKK**QSSWHHPTPHSP
RCSSPEFWILSYKSVPFIS*VEGSEGDKYPQVK
YVAVEMECIKSASSVIVFQFFPL*KLTPKGL*AS
NSFCPFIQTSPKFFVFCLPFLSFFFFFFMMIKK
MERIWMNCVNLDPSPFWPKRTLDLVPESNQFLC
*KGPFEAIKCW*EYFSVVARLPSAFKLPSCKVYV
VLKCQGDQPCP*RLHMCGIQFLPESLSFLLFLK
WWQKNELGMTLPPYWAWILRTRRCQI*DKTDHQ
SRLLWAPLWGDHCFQSHLPRLSRAGPDWWGMSVQ
KPWERPKSHSSMI*ENLPAEARNLELRCLGTSF
DILSSF*F*FLPRVTTFPVSEKVPAFLKYSDFE
NMYPKWEAPVTFCQLKREKDPPHPAHSPFLQPRF
SHMLQLLPSKALCLFFP*ILPKASPSHLPLRSW
GLC*EIF*VFLTGTTWSHVCRSSICIPAGVDFC
VGASSCP*LSPPIR*MKPTPLSRVMRVKKRGCMN
GQIPM*EEDDLIHLAFSSGSVLPHPFHLSCPQ*
ET*RNNVPYISP*LHNPSS*EIGKQI*FWFCKT
YMLQ*FFFVS*ILIGEKNSSPKVLGFTYIFINYF
RRFNSIKSCITSDHFK*QANNEL*RLFYHSCSQ
KVLMVPDRLPLRACVYFLKVNGFFSCVLVSIIG
EKI*KYMQKL*FSLDQKLIFLGQPYVFCLKDLK*
SAVM*PCGREHITSCLA*QVT*YICNWF*NQYT
ILSFCKQPSLYLGKKNCWVLDFFNINFVDMELG
KFKCLCAYVFYISFFYSVSLIQLAVGKYGIS**H
FSPKWCFGFEKGLMGRRRTYHPSFLS**T*KNG
**TVDSQENTQQGTQLSGNESSPQPPPCRWIDR
IFPD*SLGSGASVGFVFLEE*LAEWYKRHEYLLV
YKDTLIWGLHFSWFLFPVPPGVFH**VFVQGSY
L*CLPSPRKILCNILNGDRILNG*NNGWF*P*V
TVLRLDPSHSIICPLE*LSCP*RG*ERDHLEIPL
DTCGFFRV*VSSSP*ASERRVGMVKSEWLPHC*
KPRGAWHTRLCGKASKCIPSFLSCFLCLTIEAA
RGTITVCRDFLTFHI*GPPPMHW*GWALINACYC
*AIPASSSE*TRRPFT*FSASPFAFPTLLLGLL
FPLLLIRRDGRR*APITELAFGSCFLPICIYAI
CEYAIYMCQQIYLRCSFQISTQIGILSFFFF**L
V*QALVFLYKKEKQKIDYCGLHDINKQMVISKQ
RIPQSSVCCHNLQFSLTVHPIYICILILFKLYV
QGFACIYMVLREKKCYKLQI*NSNVLFH*DQKKK
RSFKRDNLLEPIKLFADEQKPILLCTENKNSCP
LV

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