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Sequences

Sequence NM_031845

GGGATAATGCTCCCGGAGAAGGATTCTGCAGCAGTTCTCAAAGGCTAGACTTGAGTGGTATTGCTGCATATGCGCTGATTCTTCAGCTTGTCTCTAACCG
AGGAAGCATTGATTGGGAGCTACTCATTCAGAAAATTAAAAGAAAGAAGCCAGAAAATATTATCAACCCTTTGAGAACACGACACAACGAACTTTATATT
TTACCACTTCCTTGAATAGTTGCAGGAGAAATAACAAGGCATTGAAGAATGGCAGATGAACGGAAAGATGAAGCAAAGGCACCTCACTGGACCTCAGCAC
CGCTAACAGAGGCATCTGCACACTCACATCCACCTGAGATTAAGGATCAAGGCGGAGCAGGGGAAGGACTTGTCCGAAGCGCCAATGGATTCCCATACAG
GGAGGATGAAGAGGGTGCCTTTGGAGAGCATGGGTCACAGGGCACCTATTCAAATACCAAAGAGAATGGGATCAACGGAGAGCTGACCTCAGCTGACAGA
GAAACAGCAGAGGAGGTGTCTGCAAGGATAGTTCAAGTAGTCACTGCTGAGGCTGTAGCAGTCCTGAAAGGTGAACAAGAGAAAGAAGCTCAACATAAAG
ACCAGACTGCAGCTCTGCCTTTAGCAGCTGAAGAAACAGCTAATCTGCCTCCTTCTCCACCCCCATCACCTGCCTCAGAACAGACTGTCACAGTGGAGGA
AGCAGCAGGTGGGGAATCAGCTCTGGCTCCCAGTGTATTTAAACAGGCAAAGGACAAAGTCTCTGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCT
CTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCAC
GGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACC
AAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGT
GAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCA
AATCCAAAATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAA
ATGTGGCTCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTT
GGTTCTCTTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACC
ATGGGGCTGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGA
ATCTCCTCAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAG
GCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCCCCAAACTGTAGTAATTGTTA
CAATTTTCTATTTAAAAAATGAATAGTACATGCAGAAATTGACCTGATTTCCATTTGCAACAGGAAGACACTGGCTTTACATGGGTTCAATTGGACAATT
ATTTTTGCTCTGCTCTGTTTTGCATGGAGTATTATTATTTTAAAAATTGCATTTTTACCTTTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCT
TGTTAAAATCCAAGCTGCTCATTTCACTATTCTGTTTCTGAGTGAGAAGATAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTC
TGATTGCAGGAAGGGAAGAGCATGTAAGAAATAAGTTTTTTTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTGGGA
CCTGGATAATTATATCAGAGTATGTCAGTCCAATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAGGAAGTGGTGTAAA
AGTGCATCCATTAGGAATGATGCACTTTCATTAGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGATTTGTGTCCACACTACCAGTTTCA
CACCCCCTTTCCATCTGTTTGATACAGTATTATAGATATAAATATATATATATTTCTCTGTGGCCATTTGTGATACTTCCTCATATACTTGAATATTATA
CTTCTTTATTCACAGTATCTGTGTCTCCTGCACCCTTTGGTGTTGCAATTTTAGATATGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCTATTTAAAAAA
AATACATTAAAAAAGACAAAAAATTTTAGCATGAAGTTGCTTTCTGTAACAACTCAAAGCCGTAACCCTGTTTTAGTGCCAGATACAAGTCTCTCCCGTG
ATGCTAGACAAAAAATTATTTTTCTTTGCTTTCACCAACATGGAGTTTGTGGGGGTGGGTCCAGTTATACATGAAAGGGTTTACAGATTGTTGGTTTAAG
ATTATGGATTTATCTCATTTTTAATCACAGGATAGTTTGGGGTTTATTCCTATTATTATTCATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTT
TTTTCCATTTGCTAAAGTTGAAAGTTGAAACTAACTATAATAGTTTGAAACATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATA
GAAGATGTTTGTCTTTCTTACCCAAAGTAAAGATCCCCTGATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACACAG
ATATCTAAATCAGTTTTTTTCCAAGACTCCAACATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAATACTGTTCTGACT
GTATATACAGTCTAGAACTCACAAATCAATTAGTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATGAAATAGTCAATGGCCTGATTAAG
GCAAAGAGCTACCAGGCTAGATGGACACTTTTTAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGCTGGTAGGTTGGATCTGAACCATTAAAATCAAAT
GGTCCACTAGGCGTATGATCTCTTTGAGCCAAATCAGTTCCTGAATATAAAGGAGGAAATGATGAGGATGTACTGAGGCAACGGGGAAGTATAGAAACAT
CCAAGACAAAAGCCAAGGGATGCAAAGGCAGAGACACAGGTGCTTTTTGGTGACCCAGTGGATATGGCAACCAGTGTAACTGCCATACAAGAAACCCTAG
GAGCAAACCCACACCACTCATTCTCAGCTAAGAGATTTTACACAGGCAAACGTGTCTTAAACCATCTATAAATCAGTTATTTTATATGACAGTCAAAACC
TTAGAAACCTTAGGATCATTATATCTATTTTCTGCCTATTAATTGCTGTGAGGTTTGATTTGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAG
TGCACCAGAAAATAGAAGAAAGGTGTGTGGAGACTTAGGGTATTTTATTACATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTA
ACAGCTCATTAGAAAAGTTTTAACCTGTGAAATAAGTATTTTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCATACT
AGAAGTCAGTTTATTACAAATACATGTCAAAAATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTATTTCTAATCACAA
CAAAATTATAATGAATAAATGTTCTTGCTTTGTATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGATCGTTTGTACCAGTAAAAGAGAGA
AACACACAGGTTAAATATCTTCTTGTGGGGTTAAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGATAACGACTCAAATTAAGCTTTTTGAGCACCACT
CTTGTGGGGACACACATACGCTGATCTAGGAATGAAATCTTCGTGGTCTCAATTCTAGATCTACTATGCCAGTTTCTCTCTGGCTTTAGCCTTTGAGAAC
CTGTATAAGAATACGTAAGTAATCCAGAGCTGTGAAGAGTTTAAAGGCCAACTTCTCCAGTGAACTCAACCTCTGGGTCACTTGCAACCAGAAATTGGAT
ACCTCATAATGATGCAGGAAAGACCCGAGTTCATGATGAGTTTCAAAGGCCACGTTCATTTAGGAACCAACTCTCTCTGGATTTACCTGCTGAGTTCCAG
CAGCGTGATGGGCTGACATCCCACCTACAAGTATGACACCTGTGTAACACCAGCTAGGTACGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAA
GAATGTACTGATTGTAGTGACCTTCTCCACACACACACACACACACACACACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATA
TAACATTCCATCAGTATTTTATTAAGGAAATAACCTGAATGTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAATAAG
GAAAATAAACTACTCATGGTCTAAATACTAGAGATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTGACGTGCTAAAATA
AGCATTGATGTTTTGAGTTTTTTTACACCTAGGATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAGGAAAAAGCTTATTTTCAAACTCA
GAAAATAAAATGTCAATCATAAAAATCTACTTCAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAAGTATACTCTGTATGCTGGGATTCCGAGGTTCCA
ACACACTGTTACAAATCTGTGGGGGGTTTCTTTCTTCTGATAATTCTAGAGCCTGTTACCATAGAAAGGCATTTCTTCAATGGCTGGTTGTAGTTAGTTC
ATGTTTTTCAATCAAATTTGCAAATGTATTTGTTGCTGTATAGTGATTGTTTTGCAAAATAAAATTGCTTGTCACCT
  • refseq_MAP2.F3 (forward primer)
  • refseq_MAP2.R3 (reverse primer)
  • Single exon skipping

Frame 0

GIMLPEKDSAAVLKG*T*VVLLHMR*FFSLSLT
EEALIGSYSFRKLKERSQKILSTL*EHDTTNFIF
YHFLE*LQEK*QGIEEWQMNGKMKQRHLTGPQH
R*QRHLHTHIHLRLRIKAEQGKDLSEAPMDSHT
GRMKRVPLESMGHRAPIQIPKRMGSTES*PQLTE
KQQRRCLQG*FK*SLLRL*QS*KVNKRKKLNIK
TRLQLCL*QLKKQLICLLLHPHHLPQNRLSQWR
KQQVGNQLWLPVYLNRQRTKSLTE*PRAQKSALL
SQDLPPFSLLGEVCQETEMRIPSLSTVLSLLQH
GGPPGQSQFAEQGRVVPQHPLPLGLLPSLLAPH
QVILHAHQALLEPLAIPGPLTHQEPPSLPSWCRV
RRRSPSYVLLQNLLRLPSSFGLLTNHCQT*RMS
NPKSDQQTTSNTSLKGGRYKLLPRK*T*AM*HP
NVAL*RTSATGQVADV*KLRV*N*ISKKRPKLKL
VLLIMLIMYLEVVMSRLTAKS*TSESMLKPVWT
MGLRSLHSPQADPAWHHPDDSAMSPRLEASTCS
NLLSLPLWLRMSLLHSLSRACEYFSFSIEIIIFR
HELLAGVGSEQLLYSFFINHKINNLIPKL**LL
QFSI*KMNSTCRN*PDFHLQQEDTGFTWVQLDN
YFCSALFCMEYYYFKNCIFTFHVPEGYPLHSEGL
VKIQAAHFTILFLSEKIKTAHCNLFQVKLNQGV
*LQEGKSM*EISFFKVLFCINGKKDSIKLLTFG
TWIIISEYVSPINYLTN*KIVAKHLSCG*GSGVK
VHPLGMMHFH*DGLVSD*NVS*SARFVSTLPVS
HPLSICLIQYYRYKYIYISLWPFVILPHILEYY
TSLFTVSVSPAPFGVAILDM*K*MLAGFSPYLKK
IH*KRQKILA*SCFL*QLKAVTLF*CQIQVSPV
MLDKKLFFFAFTNMEFVGVGPVIHERVYRLLV*
DYGFISFLITG*FGVYSYYYS*NRLKIFSLFFFF
FPFAKVES*N*L**FETCFLIFPNSICLLNSLI
EDVCLSYPK*RSPDQKEKIQYFGKL*L*NT*DT
DI*ISFFPRLQHCTL*SNTL*SSIIYQ*IILF*L
YIQSRTHKSISSSHKSFILDLQIRNEIVNGLIK
AKSYQARWTLFKNFICSFSCSGLVGWI*TIKIK
WSTRRMISLSQISS*I*RRK**GCTEATGKYRNI
QDKSQGMQRQRHRCFLVTQWIWQPV*LPYKKP*
EQTHTTHSQLRDFTQANVS*TIYKSVILYDSQN
LRNLRIIISIFCLLIAVRFDLTNLGNLFISFP*S
APENRRKVCGDLGYFITCFHSLK**LNFSRKKL
TAH*KSFNL*NKYFSQHSLKFLYKLTLGKHSAY
*KSVYYKYMSKIKIIQGTKLLDLALKQMFISNHN
KIIMNKCSCFVWKYNSLLKLTERN*SFVPVKER
NTQVKYLLVGLRGRTYLAFTLKITTQIKLFEHH
SCGDTHTLI*E*NLRGLNSRSTMPVSLWL*PLRT
CIRIRK*SRAVKSLKANFSSELNLWVTCNQKLD
TS**CRKDPSS**VSKATFI*EPTLSGFTC*VP
AA*WADIPPTSMTPV*HQLGTAGEG*RENAIKWK
NVLIVVTFSTHTHTHTHTHTYSNTASVE*SANI
*HSISILLRK*PECG*F*HSCNYSFLLFFKPQ*
GK*TTHGLNTRDKVDSWLGKEILSIPSKIDVLK*
ALMF*VFLHLGFLAWVCR*RPRLSAGKSLFSNS
ENKMSIIKIYFNFSKKKKKSTKSILCMLGFRGS
NTLLQICGGFLSSDNSRACYHRKAFLQWLVVVSS
CFSIKFANVFVAV**LFCKIKLLVT

Frame 1

G*CSRRRILQQFSKARLEWYCCICADSSACL*P
RKH*LGATHSEN*KKEARKYYQPFENTTQRTLY
FTTSLNSCRRNNKALKNGR*TER*SKGTSLDLST
ANRGICTLTST*D*GSRRSRGRTCPKRQWIPIQ
GG*RGCLWRAWVTGHLFKYQREWDQRRADLS*Q
RNSRGGVCKDSSSSHC*GCSSPER*TRERSST*R
PDCSSAFSS*RNS*SASFSTPITCLRTDCHSGG
SSRWGISSGSQCI*TGKGQSL*RSNQEPRKALF
SPKTFLHSPSSARCVRRQR*EFLLSQQFYLFFST
ADHQVRANSQSREEWYLNTHYPWVYCHHSWHPT
KLFFTHTRHSWNP*LSQDPSHTRNPQVCHLGAE
*EEGRHHTYSSKISCDSQAASAY*PTTARPEECQ
IQNRINRQHQIPA*RGAGTNCYQENRPKPCDIQ
MWLSEEHPPQARWRTCEN*ECKTRFQRKGPS*S
WFS**CSSCTWRW*CQD*QPKVELQRAC*SPCGP
WG*DHYTVPRQIQRGITPTTQQCLLVWKHQPAR
ISSACHFG*GCHCCTR*AGLVNISHLALK**YL
GMSSWQEWALSSCYIHSL*TIK*IISSPNCSNCY
NFLFKK*IVHAEIDLISICNRKTLALHGFNWTI
IFALLCFAWSIIILKIAFLPFMCLKAIHYILKA
LLKSKLLISLFCF*VRR*KLPIVTYFRLN*TKES
DCRKGRACKK*VFLKCYFV*MGRKIQLSY*HLG
PG*LYQSMSVQ*II*LIKK*LQSI*AVVEEVV*
KCIH*E*CTFIRMDSCLIRMSVDQLDLCPHYQFH
TPFPSV*YSIIDINIYIFLCGHL*YFLIYLNII
LLYSQYLCLLHPLVLQF*ICESRC*QGSLPI*K
KYIKKDKKF*HEVAFCNNSKP*PCFSARYKSLP*
C*TKNYFSLLSPTWSLWGWVQLYMKGFTDCWFK
IMDLSHF*SQDSLGFIPIIIHETDLRFFLYFSF
FFHLLKLKVETNYNSLKHVFSFFQIVSVY*IL**
KMFVFLTQSKDPLIRKKKYNTLGSYSYKTLETQ
ISKSVFFQDSNIALCKVTHCDLVLFISR*YCSD
CIYSLELTNQLVPLTNHSS*TYK*GMK*SMA*LR
QRATRLDGHFLKILSVLFLAQGW*VGSEPLKSN
GPLGV*SL*AKSVPEYKGGNDEDVLRQRGSIET
SKTKAKGCKGRDTGAFW*PSGYGNQCNCHTRNPR
SKPTPLILS*EILHRQTCLKPSINQLFYMTVKT
LETLGSLYLFSAY*LL*GLI*PIWAIYSSASLE
VHQKIEERCVET*GILLHVFIVLNSD*ISLERS*
QLIRKVLTCEISIFLNIL*SFYIS*H*VNILHT
RSQFITNTCQK*RLYKAPNY*IWH*NKCLFLIT
TKL**INVLALYGNTILY*S*QKGTDRLYQ*KRE
THRLNIFLWG*GVEPILPSLSR*RLKLSFLSTT
LVGTHIR*SRNEIFVVSILDLLCQFLSGFSL*E
PV*EYVSNPEL*RV*RPTSPVNSTSGSLATRNWI
PHNDAGKTRVHDEFQRPRSFRNQLSLDLPAEFQ
QRDGLTSHLQV*HLCNTS*VRLEKAEERMPLNG
RMY*L**PSPHTHTHTHTHTPTVIQQAWNNQPIY
NIPSVFY*GNNLNVVDFDIAAITVFFYFSSHNK
ENKLLMV*ILEIK*IHGLVRKF*AFLQRLTC*N
KH*CFEFFYT*DF*LGCVGEGQDSLQEKAYFQTQ
KIKCQS*KSTSTLAKRKKNQQKVYSVCWDSEVP
THCYKSVGGFFLLIILEPVTIERHFFNGWL*LV
HVFQSNLQMYLLLYSDCFAK*NCLSP

Frame 2

DNAPGEGFCSSSQRLDLSGIAAYALILQLVSNR
GSIDWELLIQKIKRKKPENIINPLRTRHNELYI
LPLP*IVAGEITRH*RMADERKDEAKAPHWTSA
PLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYR
EDEEGAFGEHGSQGTYSNTKENGINGELTSADR
ETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHK
DQTAALPLAAEETANLPPSPPPSPASEQTVTVEE
AAGGESALAPSVFKQAKDKVSDGVTKSPEKRSS
LPRPSSILPPRRGVSGDRDENSFSLNSSISSSA
RRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPP
SYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPS
EKKVAIIRTPPKSPATPKQLRLINQPLPDLKNV
KSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSK
CGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKV
GSLDNAHHVPGGGNVKIDSQKLNFREHAKARVD
HGAEIITQSPGRSSVASPRRLSNVSSSGSINLLE
SPQLATLAEDVTAALAKQGL*IFLI*H*NNNI*
A*ALGRSGL*AVVIFILYKP*NK*SHPQTVVIV
TIFYLKNE*YMQKLT*FPFATGRHWLYMGSIGQL
FLLCSVLHGVLLF*KLHFYLSCA*RLSTTF*RP
C*NPSCSFHYSVSE*EDKNCPL*LISG*IKPRS
LIAGREEHVRNKFF*SVILYKWEERFN*VINIWD
LDNYIRVCQSNKLFN*LKNSCKAFELWLRKWCK
SASIRNDALSLGWTRV*LECQLIS*ICVHTTSF
TPPFHLFDTVL*I*IYIYFSVAICDTSSYT*ILY
FFIHSICVSCTLWCCNFRYVKVDVSRVLSLFKK
NTLKKTKNFSMKLLSVTTQSRNPVLVPDTSLSR
DARQKIIFLCFHQHGVCGGGSSYT*KGLQIVGLR
LWIYLIFNHRIVWGLFLLLFMKPT*DFFFIFLF
FSIC*S*KLKLTIIV*NMFSHFSK*YLFIKFSN
RRCLSFLPKVKIP*SERKNTILWEAIAIKHLRHR
YLNQFFSKTPTLHSVK*HTVI*YYLSVDNTVLT
VYTV*NSQIN*FLSQIIHLRLTNKE*NSQWPD*
GKELPG*MDTF*KFYLFFFLLRAGRLDLNH*NQM
VH*AYDLFEPNQFLNIKEEMMRMY*GNGEV*KH
PRQKPRDAKAETQVLFGDPVDMATSVTAIQETL
GANPHHSFSAKRFYTGKRVLNHL*ISYFI*QSKP
*KP*DHYIYFLPINCCEV*FDQSGQFIHQLPLK
CTRK*KKGVWRLRVFYYMFS*S*IVIKFL*KEV
NSSLEKF*PVK*VFFSTFFKVFI*VNTR*TFCIL
EVSLLQIHVKNKDYTRHQTTRFGIKTNVYF*SQ
QNYNE*MFLLCMEIQFFIKVNRKELIVCTSKRE
KHTG*ISSCGVKG*NLSCLHSQDNDSN*AF*APL
LWGHTYADLGMKSSWSQF*IYYASFSLALAFEN
LYKNT*VIQSCEEFKGQLLQ*TQPLGHLQPEIG
YLIMMQERPEFMMSFKGHVHLGTNSLWIYLLSSS
SVMG*HPTYKYDTCVTPARYGWRRLKRECH*ME
ECTDCSDLLHTHTHTHTHTHLQ*YSKRGIISQY
ITFHQYFIKEIT*MWLILT*LQLQFSSIFQATIR
KINYSWSKY*R*SRFMAW*GNFKHSFKD*RAKI
SIDVLSFFTPRIFSLGV*VKAKTLCRKKLIFKL
RK*NVNHKNLLQL*QKEKKINKKYTLYAGIPRFQ
HTVTNLWGVSFF**F*SLLP*KGISSMAGCS*F
MFFNQICKCICCCIVIVLQNKIACH

Sequence NM_002374

GGGATAATGCTCCCGGAGAAGGATTCTGCAGCAGTTCTCAAAGGCTAGACTTGAGTGGTATTGCTGCATATGCGCTGATTCTTCAGCTTGTCTCTAACCG
AGGAAGCATTGATTGGGAGCTACTCATTCAGAAAATTAAAAGAAAGAAGCCAGAAAATATTATCAACCCTTTGAGAACACGACACAACGAACTTTATATT
TTACCACTTCCTTGAATAGTTGCAGGAGAAATAACAAGGCATTGAAGAATGGCAGATGAACGGAAAGATGAAGCAAAGGCACCTCACTGGACCTCAGCAC
CGCTAACAGAGGCATCTGCACACTCACATCCACCTGAGATTAAGGATCAAGGCGGAGCAGGGGAAGGACTTGTCCGAAGCGCCAATGGATTCCCATACAG
GGAGGATGAAGAGGGTGCCTTTGGAGAGCATGGGTCACAGGGCACCTATTCAAATACCAAAGAGAATGGGATCAACGGAGAGCTGACCTCAGCTGACAGA
GAAACAGCAGAGGAGGTGTCTGCAAGGATAGTTCAAGTAGTCACTGCTGAGGCTGTAGCAGTCCTGAAAGGTGAACAAGAGAAAGAAGCTCAACATAAAG
ACCAGACTGCAGCTCTGCCTTTAGCAGCTGAAGAAACAGCTAATCTGCCTCCTTCTCCACCCCCATCACCTGCCTCAGAACAGACTGTCACAGTGGAGGA
AGATTTACTTACAGCCTCGAAGATGGAGTTCCACGATCAACAGGAATTGACTCCCTCTACAGCTGAGCCTTCAGACCAGAAGGAAAAGGAGTCAGAGAAG
CAAAGTAAGCCTGGTGAAGACCTTAAACATGCTGCCTTAGTTTCTCAGCCAGAGACAACTAAAACTTACCCTGATAAAAAGGACATGCAAGGCACGGAAG
AAGAAAAAGCACCCCTAGCTTTGTTTGGGCACACTCTTGTTGCCAGCCTGGAAGACATGAAACAGAAGACAGAACCAAGCCTTGTAGTACCTGGCATTGA
CCTCCCTAAAGAGCCTCCAACTCCAAAAGAACAAAAGGACTGGTTCATCGAAATGCCAACGGAAGCAAAAAAGGATGAGTGGGGTTTAGTTGCCCCCATA
TCTCCTGGCCCTCTGACTCCCATGAGGGAAAAAGATGTATTTGATGATATCCCAAAATGGGAAGGGAAACAGTTTGATTCTCCCATGCCAAGTCCCTTTC
AAGGGGGAAGCTTCACTCTTCCTTTAGATGTCATGAAGAATGAAATAGTTACAGAAACATCGCCCTTTGCCCCTGCCTTTTTACAGCCAGATGACAAAAA
ATCTCTGCAACAAACCAGTGGCCCAGCTACTGCCAAAGATAGTTTTAAAATTGAAGAGCCCCATGAGGCTAAACCTGACAAAATGGCAGAAGCACCACCC
TCAGAGGCAATGACCTTACCCAAAGATGCTCACATTCCAGTTGTAGAAGAACATGTTATGGGGAAAGTTTTAGAGGAAGAAAAGGAGGCCATAAATCAAG
AGACTGTGCAGCAAAGGGATACTTTCACCCCCAGTGGACAGGAACCTATACTTACTGAAAAGGAAACTGAGCTGAAGCTTGAAGAAAAAACCACCATTTC
TGACAAAGAAGCTGTGCCAAAAGAGAGTAAACCCCCAAAACCTGCAGATGAAGAAATAGGCATAATTCAGACCTCCACAGAGCACACTTTCTCAGAACAG
AAAGACCAAGAGCCTACCACAGATATGTTGAAACAGGACTCGTTCCCTGTAAGTTTGGAGCAAGCAGTTACAGATTCAGCCATGACCTCTAAAACACTGG
AGAAAGCCATGACCGAACCATCTGCATTAATTGAAAAGAGCTCAATTCAGGAACTTTTTGAAATGAGAGTTGATGACAAAGATAAGATTGAAGGAGTTGG
AGCTGCAACATCAGCTGAGCTTGATATGCCATTTTATGAAGATAAATCAGGAATGTCCAAGTACTTTGAAACATCTGCCTTGAAAGAAGAAGCAACAAAA
AGCATTGAGCCAGGCAGTGATTACTATGAACTGAGTGACACTAGAGAAAGTGTCCATGAGTCTATTGATACCATGTCTCCCATGCATAAAAATGGTGACA
AGGAGTTTCAAACAGGAAAAGAATCCCAGCCCAGTCCTCCAGCACAAGAAGCAGGGTACAGCACTCTCGCACAGAGTTATCCATCAGATTTACCTGAAGA
ACCCAGTTCTCCTCAAGAAAGAATGTTCACTATTGATCCAAAAGTGTATGGAGAGAAAAGGGACCTCCACAGTAAGAATAAGGATGATTTGACCCTTAGC
AGGAGTTTAGGACTTGGTGGTAGGTCTGCAATAGAACAAAGAAGCATGTCAATCAATTTGCCGATGTCTTGCCTAGATTCCATAGCCCTTGGATTTAACT
TTGGTCGGGGACATGATCTTTCTCCTCTGGCTTCCGATATTCTAACCAACACTAGTGGAAGTATGGATGAAGGGGATGATTACCTTCCAGCCACCACACC
TGCACTGGAGAAAGCCCCTTGCTTCCCTGTAGAAAGCAAAGAGGAAGAACAGATAGAGAAAGTAAAAGCTACTGGAGAAGAAAGTACTCAAGCGGAGATA
TCATGTGAGTCTCCTTTCCTAGCCAAAGATTTTTACAAAAATGGTACTGTCATGGCACCTGACCTTCCTGAAATGCTAGATCTGGCAGGCACAAGGTCAA
GATTGGCTTCTGTGAGTGCAGATGCTGAGGTTGCCAGGAGGAAATCAGTCCCATCAGAGACTGTGGTTGAGGATAGTCGTACTGGCTTGCCCCCGGTAAC
TGATGAAAACCATGTCATTGTAAAAACGGACAGTCAGCTCGAAGACCTGGGCTACTGTGTGTTCAATAAGTACACAGTCCCATTGCCATCACCTGTTCAA
GACAGTGAGAATTTATCAGGGGAGAGTGGTACCTTTTACGAAGGCACTGATGATAAAGTTCGAAGAGATTTGGCCACAGACCTTTCACTGATTGAAGTGA
AACTGGCAGCAGCCGGAAGAGTCAAAGATGAGTTCAGTGTTGACAAAGAAGCATCCGCGCATATCTCTGGTGACAAATCAGGACTGAGTAAGGAGTTTGA
CCAAGAGAAGAAAGCTAATGATAGGTTGGATACTGTACTAGAAAAGAGTGAAGAACATGCTGATTCAAAAGAACATGCCAAGAAAACTGAAGAGGCTGGT
GATGAAATAGAAACATTCGGATTAGGAGTAACCTATGAGCAAGCTTTGGCCAAAGATTTGTCAATACCAACAGATGCATCCTCTGAGAAAGCAGAGAAGG
GTCTTAGTTCAGTGCCAGAGATAGCTGAGGTAGAACCATCCAAAAAGGTGGAACAAGGTCTGGATTTTGCTGTCCAGGGTCAACTAGATGTTAAAATTAG
TGACTTTGGACAGATGGCTTCAGGGCTAAACATAGATGATAGAAGGGCAACAGAGCTAAAACTTGAGGCTACACAGGACATGACCCCCTCATCCAAAGCA
CCGCAGGAGGCAGATGCATTTATGGGTGTTGAGTCTGGCCACATGAAAGAAGGCACTAAAGTTAGTGAGACAGAAGTCAAAGAGAAGGTGGCCAAGCCTG
ACTTGGTGCACCAGGAGGCTGTAGACAAGGAGGAGTCCTATGAATCTAGTGGTGAGCATGAAAGTCTCACCATGGAGTCCTTGAAAGCTGATGAGGGCAA
GAAGGAAACATCTCCAGAATCATCTCTAATTCAAGATGAGATTGCCGTCAAATTGTCAGTGGAAATACCTTGCCCACCTGCTGTTTCAGAGGCTGATTTA
GCCACAGATGAGAGAGCTGATGTCCAGATGGAATTTATTCAGGGGCCAAAAGAAGAAAGCAAAGAGACCCCAGATATATCCATCACGCCTTCTGATGTTG
CAGAGCCATTGCATGAAACGATCGTATCTGAACCAGCAGAGATTCAGAGTGAGGAAGAAGAGATAGAAGCCCAGGGAGAATATGATAAACTGCTCTTCCG
CTCAGACACCCTTCAGATAACTGACCTGGGTGTCTCAGGTGCCAGGGAGGAATTTGTGGAGACCTGCCCAAGTGAACACAAAGGAGTGATTGAGTCTGTT
GTGACCATCGAGGATGATTTCATCACTGTAGTGCAAACCACAACTGATGAAGGGGAGTCAGGGTCCCACAGCGTGCGTTTTGCAGCCCTAGAGCAGCCTG
AGGTGGAAAGGAGACCATCTCCTCATGATGAAGAAGAGTTTGAAGTAGAAGAGGCAGCTGAAGCCCAGGCAGAACCCAAAGATGGTTCCCCAGAGGCTCC
AGCTTCCCCTGAGAGAGAAGAGGTTGCACTTTCTGAATATAAGACAGAAACCTATGACGATTACAAAGATGAGACCACCATTGACGACTCCATCATGGAC
GCTGACAGCCTCTGGGTGGACACTCAAGATGATGATAGGAGCATCATGACAGAACAGTTAGAAACTATTCCTAAAGAGGAGAAAGCTGAAAAGGAAGCTC
GGAGATCATCTCTTGAGAAACATAGAAAAGAAAAGCCTTTTAAAACCGGGAGAGGCAGAATTTCCACTCCTGAAAGAAAAGTAGCTAAAAAGGAACCTAG
CACAGTCTCCAGAGATGAAGTGAGAAGGAAAAAAGCAGTTTATAAGAAGGCTGAACTTGCTAAAAAAACAGAAGTTCAGGCCCACTCTCCCTCCAGGAAA
TTCATTTTAAAACCTGCTATCAAATATACTAGACCAACTCATCTCTCCTGTGTTAAGCGGAAAACCACAGCAGCAGGTGGGGAATCAGCTCTGGCTCCCA
GTGTATTTAAACAGGCAAAGGACAAAGTCTCTGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCCTCCTCG
GCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATTCGCAGA
GCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCACTCCTG
GAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTACTCCTCC
AAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAACATCAAA
TACCAGCCTAAAGGGGGGCAGGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAGGC
CAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGG
AGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGC
AGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATG
TCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGC
AGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCCCCAAACTGTAGTAATTGTTACAATTTTCTATTTAAAAAATGAATAGTACATG
CAGAAATTGACCTGATTTCCATTTGCAACAGGAAGACACTGGCTTTACATGGGTTCAATTGGACAATTATTTTTGCTCTGCTCTGTTTTGCATGGAGTAT
TATTATTTTAAAAATTGCATTTTTACCTTTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAAATCCAAGCTGCTCATTTCACTATTC
TGTTTCTGAGTGAGAAGATAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGCAGGAAGGGAAGAGCATGTAAGAAAT
AAGTTTTTTTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTGGGACCTGGATAATTATATCAGAGTATGTCAGTCCA
ATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAGGAAGTGGTGTAAAAGTGCATCCATTAGGAATGATGCACTTTCATT
AGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGATTTGTGTCCACACTACCAGTTTCACACCCCCTTTCCATCTGTTTGATACAGTATTA
TAGATATAAATATATATATATTTCTCTGTGGCCATTTGTGATACTTCCTCATATACTTGAATATTATACTTCTTTATTCACAGTATCTGTGTCTCCTGCA
CCCTTTGGTGTTGCAATTTTAGATATGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCTATTTAAAAAAAATACATTAAAAAAGACAAAAAATTTTAGCAT
GAAGTTGCTTTCTGTAACAACTCAAAGCCGTAACCCTGTTTTAGTGCCAGATACAAGTCTCTCCCGTGATGCTAGACAAAAAATTATTTTTCTTTGCTTT
CACCAACATGGAGTTTGTGGGGGTGGGTCCAGTTATACATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGGATTTATCTCATTTTTAATCACAGGA
TAGTTTGGGGTTTATTCCTATTATTATTCATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCATTTGCTAAAGTTGAAAGTTGAAACT
AACTATAATAGTTTGAAACATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATGTTTGTCTTTCTTACCCAAAGTAAAG
ATCCCCTGATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACACAGATATCTAAATCAGTTTTTTTCCAAGACTCCAA
CATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAATACTGTTCTGACTGTATATACAGTCTAGAACTCACAAATCAATTA
GTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATGAAATAGTCAATGGCCTGATTAAGGCAAAGAGCTACCAGGCTAGATGGACACTTTT
TAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGCTGGTAGGTTGGATCTGAACCATTAAAATCAAATGGTCCACTAGGCGTATGATCTCTTTGAGCCAA
ATCAGTTCCTGAATATAAAGGAGGAAATGATGAGGATGTACTGAGGCAACGGGGAAGTATAGAAACATCCAAGACAAAAGCCAAGGGATGCAAAGGCAGA
GACACAGGTGCTTTTTGGTGACCCAGTGGATATGGCAACCAGTGTAACTGCCATACAAGAAACCCTAGGAGCAAACCCACACCACTCATTCTCAGCTAAG
AGATTTTACACAGGCAAACGTGTCTTAAACCATCTATAAATCAGTTATTTTATATGACAGTCAAAACCTTAGAAACCTTAGGATCATTATATCTATTTTC
TGCCTATTAATTGCTGTGAGGTTTGATTTGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCAGAAAATAGAAGAAAGGTGTGTGGAG
ACTTAGGGTATTTTATTACATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTCATTAGAAAAGTTTTAACCTGTGAAA
TAAGTATTTTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCATACTAGAAGTCAGTTTATTACAAATACATGTCAAAA
ATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTATTTCTAATCACAACAAAATTATAATGAATAAATGTTCTTGCTTTG
TATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGATCGTTTGTACCAGTAAAAGAGAGAAACACACAGGTTAAATATCTTCTTGTGGGGTT
AAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGATAACGACTCAAATTAAGCTTTTTGAGCACCACTCTTGTGGGGACACACATACGCTGATCTAGGAA
TGAAATCTTCGTGGTCTCAATTCTAGATCTACTATGCCAGTTTCTCTCTGGCTTTAGCCTTTGAGAACCTGTATAAGAATACGTAAGTAATCCAGAGCTG
TGAAGAGTTTAAAGGCCAACTTCTCCAGTGAACTCAACCTCTGGGTCACTTGCAACCAGAAATTGGATACCTCATAATGATGCAGGAAAGACCCGAGTTC
ATGATGAGTTTCAAAGGCCACGTTCATTTAGGAACCAACTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTGATGGGCTGACATCCCACCTACAAGT
ATGACACCTGTGTAACACCAGCTAGGTACGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTACTGATTGTAGTGACCTTCTCCACAC
ACACACACACACACACACACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATTCCATCAGTATTTTATTAAGGAAATA
ACCTGAATGTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAATAAGGAAAATAAACTACTCATGGTCTAAATACTAGA
GATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTGACGTGCTAAAATAAGCATTGATGTTTTGAGTTTTTTTACACCTAG
GATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAGGAAAAAGCTTATTTTCAAACTCAGAAAATAAAATGTCAATCATAAAAATCTACTT
CAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAAGTATACTCTGTATGCTGGGATTCCGAGGTTCCAACACACTGTTACAAATCTGTGGGGGGTTTCTT
TCTTCTGATAATTCTAGAGCCTGTTACCATAGAAAGGCATTTCTTCAATGGCTGGTTGTAGTTAGTTCATGTTTTTCAATCAAATTTGCAAATGTATTTG
TTGCTGTATAGTGATTGTTTTGCAAAATAAAATTGCTTGTCACCT
  • refseq_MAP2.F3 (forward primer)
  • refseq_MAP2.R3 (reverse primer)
  • Single exon skipping

Frame 0

GIMLPEKDSAAVLKG*T*VVLLHMR*FFSLSLT
EEALIGSYSFRKLKERSQKILSTL*EHDTTNFIF
YHFLE*LQEK*QGIEEWQMNGKMKQRHLTGPQH
R*QRHLHTHIHLRLRIKAEQGKDLSEAPMDSHT
GRMKRVPLESMGHRAPIQIPKRMGSTES*PQLTE
KQQRRCLQG*FK*SLLRL*QS*KVNKRKKLNIK
TRLQLCL*QLKKQLICLLLHPHHLPQNRLSQWR
KIYLQPRRWSSTINRN*LPLQLSLQTRRKRSQRS
KVSLVKTLNMLP*FLSQRQLKLTLIKRTCKARK
KKKHP*LCLGTLLLPAWKT*NRRQNQAL*YLAL
TSLKSLQLQKNKRTGSSKCQRKQKRMSGV*LPPY
LLAL*LP*GKKMYLMISQNGKGNSLILPCQVPF
KGEASLFL*MS*RMK*LQKHRPLPLPFYSQMTK
NLCNKPVAQLLPKIVLKLKSPMRLNLTKWQKHHP
QRQ*PYPKMLTFQL*KNMLWGKF*RKKRRP*IK
RLCSKGILSPPVDRNLYLLKRKLS*SLKKKPPF
LTKKLCQKRVNPQNLQMKK*A*FRPPQSTLSQNR
KTKSLPQIC*NRTRSL*VWSKQLQIQP*PLKHW
RKP*PNHLH*LKRAQFRNFLK*ELMTKIRLKEL
ELQHQLSLICHFMKINQECPSTLKHLP*KKKQQK
ALSQAVITMN*VTLEKVSMSLLIPCLPCIKMVT
RSFKQEKNPSPVLQHKKQGTALSHRVIHQIYLK
NPVLLKKECSLLIQKCMERKGTSTVRIRMI*PLA
GV*DLVVGLQ*NKEACQSICRCLA*IP*PLDLT
LVGDMIFLLWLPIF*PTLVEVWMKGMITFQPPH
LHWRKPLASL*KAKRKNR*RK*KLLEKKVLKRRY
HVSLLS*PKIFTKMVLSWHLTFLKC*IWQAQGQ
DWLL*VQMLRLPGGNQSHQRLWLRIVVLACPR*
LMKTMSL*KRTVSSKTWATVCSISTQSHCHHLFK
TVRIYQGRVVPFTKALMIKFEEIWPQTFH*LK*
NWQQPEESKMSSVLTKKHPRISLVTNQD*VRSL
TKRRKLMIGWILY*KRVKNMLIQKNMPRKLKRLV
MK*KHSD*E*PMSKLWPKICQYQQMHPLRKQRR
VLVQCQR*LR*NHPKRWNKVWILLSRVN*MLKL
VTLDRWLQG*T*MIEGQQS*NLRLHRT*PPHPKH
RRRQMHLWVLSLAT*KKALKLVRQKSKRRWPSL
TWCTRRL*TRRSPMNLVVSMKVSPWSP*KLMRA
RRKHLQNHL*FKMRLPSNCQWKYLAHLLFQRLI*
PQMRELMSRWNLFRGQKKKAKRPQIYPSRLLML
QSHCMKRSYLNQQRFRVRKKR*KPRENMINCSS
AQTPFR*LTWVSQVPGRNLWRPAQVNTKE*LSLL
*PSRMISSL*CKPQLMKGSQGPTACVLQP*SSL
RWKGDHLLMMKKSLK*KRQLKPRQNPKMVPQRL
QLPLREKRLHFLNIRQKPMTITKMRPPLTTPSWT
LTASGWTLKMMIGAS*QNS*KLFLKRRKLKRKL
GDHLLRNIEKKSLLKPGEAEFPLLKEK*LKRNL
AQSPEMK*EGKKQFIRRLNLLKKQKFRPTLPPGN
SF*NLLSNILDQLISPVLSGKPQQQVGNQLWLP
VYLNRQRTKSLTE*PRAQKSALLSQDLPPFSLL
GEVCQETEMRIPSLSTVLSLLQHGGPPGQSQFAE
QGRVVPQHPLPLGLLPSLLAPHQVILHAHQALL
EPLAIPGPLTHQEPPSLPSWCRVRRRSPSYVLL
QNLLRLPSSFGLLTNHCQT*RMSNPKSDQQTTSN
TSLKGGRYKLLPRK*T*AM*HPNVAL*RTSATG
QVADV*KLRV*N*ISKKRPKLKLVLLIMLIMYL
EVVMSRLTAKS*TSESMLKPVWTMGLRSLHSPQA
DPAWHHPDDSAMSPRLEASTCSNLLSLPLWLRM
SLLHSLSRACEYFSFSIEIIIFRHELLAGVGSE
QLLYSFFINHKINNLIPKL**LLQFSI*KMNSTC
RN*PDFHLQQEDTGFTWVQLDNYFCSALFCMEY
YYFKNCIFTFHVPEGYPLHSEGLVKIQAAHFTI
LFLSEKIKTAHCNLFQVKLNQGV*LQEGKSM*EI
SFFKVLFCINGKKDSIKLLTFGTWIIISEYVSP
INYLTN*KIVAKHLSCG*GSGVKVHPLGMMHFH
*DGLVSD*NVS*SARFVSTLPVSHPLSICLIQYY
RYKYIYISLWPFVILPHILEYYTSLFTVSVSPA
PFGVAILDM*K*MLAGFSPYLKKIH*KRQKILA
*SCFL*QLKAVTLF*CQIQVSPVMLDKKLFFFAF
TNMEFVGVGPVIHERVYRLLV*DYGFISFLITG
*FGVYSYYYS*NRLKIFSLFFFFFPFAKVES*N
*L**FETCFLIFPNSICLLNSLIEDVCLSYPK*R
SPDQKEKIQYFGKL*L*NT*DTDI*ISFFPRLQ
HCTL*SNTL*SSIIYQ*IILF*LYIQSRTHKSI
SSSHKSFILDLQIRNEIVNGLIKAKSYQARWTLF
KNFICSFSCSGLVGWI*TIKIKWSTRRMISLSQ
ISS*I*RRK**GCTEATGKYRNIQDKSQGMQRQ
RHRCFLVTQWIWQPV*LPYKKP*EQTHTTHSQLR
DFTQANVS*TIYKSVILYDSQNLRNLRIIISIF
CLLIAVRFDLTNLGNLFISFP*SAPENRRKVCG
DLGYFITCFHSLK**LNFSRKKLTAH*KSFNL*N
KYFSQHSLKFLYKLTLGKHSAY*KSVYYKYMSK
IKIIQGTKLLDLALKQMFISNHNKIIMNKCSCF
VWKYNSLLKLTERN*SFVPVKERNTQVKYLLVGL
RGRTYLAFTLKITTQIKLFEHHSCGDTHTLI*E
*NLRGLNSRSTMPVSLWL*PLRTCIRIRK*SRA
VKSLKANFSSELNLWVTCNQKLDTS**CRKDPSS
**VSKATFI*EPTLSGFTC*VPAA*WADIPPTS
MTPV*HQLGTAGEG*RENAIKWKNVLIVVTFST
HTHTHTHTHTYSNTASVE*SANI*HSISILLRK*
PECG*F*HSCNYSFLLFFKPQ*GK*TTHGLNTR
DKVDSWLGKEILSIPSKIDVLK*ALMF*VFLHL
GFLAWVCR*RPRLSAGKSLFSNSENKMSIIKIYF
NFSKKKKKSTKSILCMLGFRGSNTLLQICGGFL
SSDNSRACYHRKAFLQWLVVVSSCFSIKFANVF
VAV**LFCKIKLLVT

Frame 1

G*CSRRRILQQFSKARLEWYCCICADSSACL*P
RKH*LGATHSEN*KKEARKYYQPFENTTQRTLY
FTTSLNSCRRNNKALKNGR*TER*SKGTSLDLST
ANRGICTLTST*D*GSRRSRGRTCPKRQWIPIQ
GG*RGCLWRAWVTGHLFKYQREWDQRRADLS*Q
RNSRGGVCKDSSSSHC*GCSSPER*TRERSST*R
PDCSSAFSS*RNS*SASFSTPITCLRTDCHSGG
RFTYSLEDGVPRSTGIDSLYS*AFRPEGKGVRE
AK*AW*RP*TCCLSFSARDN*NLP**KGHARHGR
RKSTPSFVWAHSCCQPGRHETEDRTKPCSTWH*
PP*RASNSKRTKGLVHRNANGSKKG*VGFSCPH
ISWPSDSHEGKRCI**YPKMGRETV*FSHAKSLS
RGKLHSSFRCHEE*NSYRNIALCPCLFTAR*QK
ISATNQWPSYCQR*F*N*RAP*G*T*QNGRSTT
LRGNDLTQRCSHSSCRRTCYGESFRGRKGGHKSR
DCAAKGYFHPQWTGTYTY*KGN*AEA*RKNHHF
*QRSCAKRE*TPKTCR*RNRHNSDLHRAHFLRT
ERPRAYHRYVETGLVPCKFGASSYRFSHDL*NTG
ESHDRTICIN*KELNSGTF*NES**QR*D*RSW
SCNIS*A*YAIL*R*IRNVQVL*NICLERRSNK
KH*ARQ*LL*TE*H*RKCP*VY*YHVSHA*KW*Q
GVSNRKRIPAQSSSTRSRVQHSRTELSIRFT*R
TQFSSRKNVHY*SKSVWREKGPPQ*E*G*FDP*
QEFRTWW*VCNRTKKHVNQFADVLPRFHSPWI*L
WSGT*SFSSGFRYSNQH*WKYG*RG*LPSSHHT
CTGESPLLPCRKQRGRTDRESKSYWRRKYSSGD
IM*VSFPSQRFLQKWYCHGT*PS*NARSGRHKVK
IGFCECRC*GCQEEISPIRDCG*G*SYWLAPGN
**KPCHCKNGQSARRPGLLCVQ*VHSPIAITCS
RQ*EFIRGEWYLLRRH***SSKRFGHRPFTD*SE
TGSSRKSQR*VQC*QRSIRAYLW*QIRTE*GV*
PREES***VGYCTRKE*RTC*FKRTCQEN*RGW
**NRNIRIRSNL*ASFGQRFVNTNRCIL*ESREG
S*FSARDS*GRTIQKGGTRSGFCCPGSTRC*N*
*LWTDGFRAKHR**KGNRAKT*GYTGHDPLIQS
TAGGRCIYGC*VWPHERRH*S**DRSQREGGQA*
LGAPGGCRQGGVL*I*W*A*KSHHGVLES**GQ
EGNISRIISNSR*DCRQIVSGNTLPTCCFRG*F
SHR*ES*CPDGIYSGAKRRKQRDPRYIHHAF*CC
RAIA*NDRI*TSRDSE*GRRDRSPGRI**TALP
LRHPSDN*PGCLRCQGGICGDLPK*TQRSD*VC
CDHRG*FHHCSANHN**RGVRVPQRAFCSPRAA*
GGKETISS**RRV*SRRGS*SPGRTQRWFPRGS
SFP*ERRGCTF*I*DRNL*RLQR*DHH*RLHHG
R*QPLGGHSR***EHHDRTVRNYS*RGES*KGSS
EIIS*ET*KRKAF*NRERQNFHS*KKSS*KGT*
HSLQR*SEKEKSSL*EG*TC*KNRSSGPLSLQE
IHFKTCYQIY*TNSSLLC*AENHSSRWGISSGSQ
CI*TGKGQSL*RSNQEPRKALFSPKTFLHSPSS
ARCVRRQR*EFLLSQQFYLFFSTADHQVRANSQ
SREEWYLNTHYPWVYCHHSWHPTKLFFTHTRHSW
NP*LSQDPSHTRNPQVCHLGAE*EEGRHHTYSS
KISCDSQAASAY*PTTARPEECQIQNRINRQHQ
IPA*RGAGTNCYQENRPKPCDIQMWLSEEHPPQA
RWRTCEN*ECKTRFQRKGPS*SWFS**CSSCTW
RW*CQD*QPKVELQRAC*SPCGPWG*DHYTVPR
QIQRGITPTTQQCLLVWKHQPARISSACHFG*GC
HCCTR*AGLVNISHLALK**YLGMSSWQEWALS
SCYIHSL*TIK*IISSPNCSNCYNFLFKK*IVH
AEIDLISICNRKTLALHGFNWTIIFALLCFAWSI
IILKIAFLPFMCLKAIHYILKALLKSKLLISLF
CF*VRR*KLPIVTYFRLN*TKESDCRKGRACKK
*VFLKCYFV*MGRKIQLSY*HLGPG*LYQSMSVQ
*II*LIKK*LQSI*AVVEEVV*KCIH*E*CTFI
RMDSCLIRMSVDQLDLCPHYQFHTPFPSV*YSI
IDINIYIFLCGHL*YFLIYLNIILLYSQYLCLLH
PLVLQF*ICESRC*QGSLPI*KKYIKKDKKF*H
EVAFCNNSKP*PCFSARYKSLP*C*TKNYFSLL
SPTWSLWGWVQLYMKGFTDCWFKIMDLSHF*SQD
SLGFIPIIIHETDLRFFLYFSFFFHLLKLKVET
NYNSLKHVFSFFQIVSVY*IL**KMFVFLTQSK
DPLIRKKKYNTLGSYSYKTLETQISKSVFFQDSN
IALCKVTHCDLVLFISR*YCSDCIYSLELTNQL
VPLTNHSS*TYK*GMK*SMA*LRQRATRLDGHF
LKILSVLFLAQGW*VGSEPLKSNGPLGV*SL*AK
SVPEYKGGNDEDVLRQRGSIETSKTKAKGCKGR
DTGAFW*PSGYGNQCNCHTRNPRSKPTPLILS*
EILHRQTCLKPSINQLFYMTVKTLETLGSLYLFS
AY*LL*GLI*PIWAIYSSASLEVHQKIEERCVE
T*GILLHVFIVLNSD*ISLERS*QLIRKVLTCE
ISIFLNIL*SFYIS*H*VNILHTRSQFITNTCQK
*RLYKAPNY*IWH*NKCLFLITTKL**INVLAL
YGNTILY*S*QKGTDRLYQ*KRETHRLNIFLWG
*GVEPILPSLSR*RLKLSFLSTTLVGTHIR*SRN
EIFVVSILDLLCQFLSGFSL*EPV*EYVSNPEL
*RV*RPTSPVNSTSGSLATRNWIPHNDAGKTRV
HDEFQRPRSFRNQLSLDLPAEFQQRDGLTSHLQV
*HLCNTS*VRLEKAEERMPLNGRMY*L**PSPH
THTHTHTHTPTVIQQAWNNQPIYNIPSVFY*GN
NLNVVDFDIAAITVFFYFSSHNKENKLLMV*ILE
IK*IHGLVRKF*AFLQRLTC*NKH*CFEFFYT*
DF*LGCVGEGQDSLQEKAYFQTQKIKCQS*KST
STLAKRKKNQQKVYSVCWDSEVPTHCYKSVGGFF
LLIILEPVTIERHFFNGWL*LVHVFQSNLQMYL
LLYSDCFAK*NCLSP

Frame 2

DNAPGEGFCSSSQRLDLSGIAAYALILQLVSNR
GSIDWELLIQKIKRKKPENIINPLRTRHNELYI
LPLP*IVAGEITRH*RMADERKDEAKAPHWTSA
PLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYR
EDEEGAFGEHGSQGTYSNTKENGINGELTSADR
ETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHK
DQTAALPLAAEETANLPPSPPPSPASEQTVTVEE
DLLTASKMEFHDQQELTPSTAEPSDQKEKESEK
QSKPGEDLKHAALVSQPETTKTYPDKKDMQGTE
EEKAPLALFGHTLVASLEDMKQKTEPSLVVPGID
LPKEPPTPKEQKDWFIEMPTEAKKDEWGLVAPI
SPGPLTPMREKDVFDDIPKWEGKQFDSPMPSPF
QGGSFTLPLDVMKNEIVTETSPFAPAFLQPDDKK
SLQQTSGPATAKDSFKIEEPHEAKPDKMAEAPP
SEAMTLPKDAHIPVVEEHVMGKVLEEEKEAINQ
ETVQQRDTFTPSGQEPILTEKETELKLEEKTTIS
DKEAVPKESKPPKPADEEIGIIQTSTEHTFSEQ
KDQEPTTDMLKQDSFPVSLEQAVTDSAMTSKTL
EKAMTEPSALIEKSSIQELFEMRVDDKDKIEGVG
AATSAELDMPFYEDKSGMSKYFETSALKEEATK
SIEPGSDYYELSDTRESVHESIDTMSPMHKNGD
KEFQTGKESQPSPPAQEAGYSTLAQSYPSDLPEE
PSSPQERMFTIDPKVYGEKRDLHSKNKDDLTLS
RSLGLGGRSAIEQRSMSINLPMSCLDSIALGFN
FGRGHDLSPLASDILTNTSGSMDEGDDYLPATTP
ALEKAPCFPVESKEEEQIEKVKATGEESTQAEI
SCESPFLAKDFYKNGTVMAPDLPEMLDLAGTRS
RLASVSADAEVARRKSVPSETVVEDSRTGLPPVT
DENHVIVKTDSQLEDLGYCVFNKYTVPLPSPVQ
DSENLSGESGTFYEGTDDKVRRDLATDLSLIEV
KLAAAGRVKDEFSVDKEASAHISGDKSGLSKEFD
QEKKANDRLDTVLEKSEEHADSKEHAKKTEEAG
DEIETFGLGVTYEQALAKDLSIPTDASSEKAEK
GLSSVPEIAEVEPSKKVEQGLDFAVQGQLDVKIS
DFGQMASGLNIDDRRATELKLEATQDMTPSSKA
PQEADAFMGVESGHMKEGTKVSETEVKEKVAKP
DLVHQEAVDKEESYESSGEHESLTMESLKADEGK
KETSPESSLIQDEIAVKLSVEIPCPPAVSEADL
ATDERADVQMEFIQGPKEESKETPDISITPSDV
AEPLHETIVSEPAEIQSEEEEIEAQGEYDKLLFR
SDTLQITDLGVSGAREEFVETCPSEHKGVIESV
VTIEDDFITVVQTTTDEGESGSHSVRFAALEQP
EVERRPSPHDEEEFEVEEAAEAQAEPKDGSPEAP
ASPEREEVALSEYKTETYDDYKDETTIDDSIMD
ADSLWVDTQDDDRSIMTEQLETIPKEEKAEKEA
RRSSLEKHRKEKPFKTGRGRISTPERKVAKKEPS
TVSRDEVRRKKAVYKKAELAKKTEVQAHSPSRK
FILKPAIKYTRPTHLSCVKRKTTAAGGESALAP
SVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPR
RGVSGDRDENSFSLNSSISSSARRTTRSEPIRR
AGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTP
GTPSYPRTPHTPGTPKSAILVPSEKKVAIIRTPP
KSPATPKQLRLINQPLPDLKNVKSKIGSTDNIK
YQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHR
PGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPG
GGNVKIDSQKLNFREHAKARVDHGAEIITQSPG
RSSVASPRRLSNVSSSGSINLLESPQLATLAED
VTAALAKQGL*IFLI*H*NNNI*A*ALGRSGL*A
VVIFILYKP*NK*SHPQTVVIVTIFYLKNE*YM
QKLT*FPFATGRHWLYMGSIGQLFLLCSVLHGV
LLF*KLHFYLSCA*RLSTTF*RPC*NPSCSFHYS
VSE*EDKNCPL*LISG*IKPRSLIAGREEHVRN
KFF*SVILYKWEERFN*VINIWDLDNYIRVCQS
NKLFN*LKNSCKAFELWLRKWCKSASIRNDALSL
GWTRV*LECQLIS*ICVHTTSFTPPFHLFDTVL
*I*IYIYFSVAICDTSSYT*ILYFFIHSICVSC
TLWCCNFRYVKVDVSRVLSLFKKNTLKKTKNFSM
KLLSVTTQSRNPVLVPDTSLSRDARQKIIFLCF
HQHGVCGGGSSYT*KGLQIVGLRLWIYLIFNHR
IVWGLFLLLFMKPT*DFFFIFLFFSIC*S*KLKL
TIIV*NMFSHFSK*YLFIKFSNRRCLSFLPKVK
IP*SERKNTILWEAIAIKHLRHRYLNQFFSKTP
TLHSVK*HTVI*YYLSVDNTVLTVYTV*NSQIN*
FLSQIIHLRLTNKE*NSQWPD*GKELPG*MDTF
*KFYLFFFLLRAGRLDLNH*NQMVH*AYDLFEP
NQFLNIKEEMMRMY*GNGEV*KHPRQKPRDAKAE
TQVLFGDPVDMATSVTAIQETLGANPHHSFSAK
RFYTGKRVLNHL*ISYFI*QSKP*KP*DHYIYF
LPINCCEV*FDQSGQFIHQLPLKCTRK*KKGVWR
LRVFYYMFS*S*IVIKFL*KEVNSSLEKF*PVK
*VFFSTFFKVFI*VNTR*TFCILEVSLLQIHVK
NKDYTRHQTTRFGIKTNVYF*SQQNYNE*MFLLC
MEIQFFIKVNRKELIVCTSKREKHTG*ISSCGV
KG*NLSCLHSQDNDSN*AF*APLLWGHTYADLG
MKSSWSQF*IYYASFSLALAFENLYKNT*VIQSC
EEFKGQLLQ*TQPLGHLQPEIGYLIMMQERPEF
MMSFKGHVHLGTNSLWIYLLSSSSVMG*HPTYK
YDTCVTPARYGWRRLKRECH*MEECTDCSDLLHT
HTHTHTHTHLQ*YSKRGIISQYITFHQYFIKEI
T*MWLILT*LQLQFSSIFQATIRKINYSWSKY*
R*SRFMAW*GNFKHSFKD*RAKISIDVLSFFTPR
IFSLGV*VKAKTLCRKKLIFKLRK*NVNHKNLL
QL*QKEKKINKKYTLYAGIPRFQHTVTNLWGVS
FF**F*SLLP*KGISSMAGCS*FMFFNQICKCIC
CCIVIVLQNKIACH

Sequence NM_001039538

AGTCTGGGGCGGGCGCTCGGGCTGCGCGGGCTCTGGGCAGCAGCAGCAGCAGCAGCAGCATCCTCTCTTCCTTTACTTCCCTTCCGCTTCTTTCTCTTCC
TTCTCCTTCTTTTTCCCCCCCCTCCCCTTCTTCCCCTAACCCTTCTACCCCTCTCCTTTTTCTCCGGAGGGCGCTAAGTCCGTGAGCGGTGGCAGTCGCG
ACCGCGGGTGCATCCAGTTTCTGCGCCCAGATTTTATTGATCTAATCCAAAGTATCTTATAACTTCTGGCTGGAATTAAGATTCTTCAGCTTGTCTCTAA
CCGAGGAAGCATTGATTGGGAGCTACTCATTCAGAAAATTAAAAGAAAGAAGCCAGAAAATATTATCAACCCTTTGAGAACACGACACAACGAACTTTAT
ATTTTACCACTTCCTTGAATAGTTGCAGGAGAAATAACAAGGCATTGAAGAATGGCAGATGAACGGAAAGATGAAGCAAAGGCACCTCACTGGACCTCAG
CACCGCTAACAGAGGCATCTGCACACTCACATCCACCTGAGATTAAGGATCAAGGCGGAGCAGGGGAAGGACTTGTCCGAAGCGCCAATGGATTCCCATA
CAGGGAGGATGAAGAGGGTGCCTTTGGAGAGCATGGGTCACAGGGCACCTATTCAAATACCAAAGAGAATGGGATCAACGGAGAGCTGACCTCAGCTGAC
AGAGAAACAGCAGAGGAGGTGTCTGCAAGGATAGTTCAAGTAGTCACTGCTGAGGCTGTAGCAGTCCTGAAAGGTGAACAAGAGAAAGAAGCTCAACATA
AAGACCAGACTGCAGCTCTGCCTTTAGCAGCTGAAGAAACAGCTAATCTGCCTCCTTCTCCACCCCCATCACCTGCCTCAGAACAGACTGTCACAGTGGA
GGAAGCAGCAGGTGGGGAATCAGCTCTGGCTCCCAGTGTATTTAAACAGGCAAAGGACAAAGTCTCTAATTCTACCTTGTCAAAGATTCCTGCTTTACAG
GGTAGCACAAAGTCCCCAAGATACAGCTCAGCCTGCCCTAGCACGACTAAAAGGGCTACATTTTCTGACAGTTTATTAATACAGCCCACCTCAGCAGGCT
CCACAGACCGTTTGCCATACTCAAAATCAGGGAACAAGGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCTCTCCCAAGACCTTCCTCCATTCTCCC
TCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCACGGCGGACCACCAGGTCAGAGCCAATT
CGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACCAAGTTATTCTTCACGCACACCAGGCA
CTCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGTGAGAAGAAGGTCGCCATCATACGTAC
TCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCAAATCCAAAATCGGATCAACAGACAAC
ATCAAATACCAGCCTAAAGGGGGGCAGGTTAGGATTTTAAACAAGAAGATCGATTTTAGCAAAGTTCAGTCCAGATGTGGTTCCAAGGATAACATCAAAC
ATTCGGCTGGGGGCGGAAATGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGCTCTCTGAAGAACATCCGCCACAGGCC
AGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTCTTGATAATGCTCATCATGTACCTGGA
GGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGCTGAGATCATTACACAGTCCCCAGGCA
GATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCTCAGCTTGCCACTTTGGCTGAGGATGT
CACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAGCTCTTGGCAGGAGTGGGCTCTGAGCA
GTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCCCCAAACTGTAGTAATTGTTACAATTTTCTATTTAAAAAATGAATAGTACATGC
AGAAATTGACCTGATTTCCATTTGCAACAGGAAGACACTGGCTTTACATGGGTTCAATTGGACAATTATTTTTGCTCTGCTCTGTTTTGCATGGAGTATT
ATTATTTTAAAAATTGCATTTTTACCTTTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAAATCCAAGCTGCTCATTTCACTATTCT
GTTTCTGAGTGAGAAGATAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGCAGGAAGGGAAGAGCATGTAAGAAATA
AGTTTTTTTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTGGGACCTGGATAATTATATCAGAGTATGTCAGTCCAA
TAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAGGAAGTGGTGTAAAAGTGCATCCATTAGGAATGATGCACTTTCATTA
GGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGATTTGTGTCCACACTACCAGTTTCACACCCCCTTTCCATCTGTTTGATACAGTATTAT
AGATATAAATATATATATATTTCTCTGTGGCCATTTGTGATACTTCCTCATATACTTGAATATTATACTTCTTTATTCACAGTATCTGTGTCTCCTGCAC
CCTTTGGTGTTGCAATTTTAGATATGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCTATTTAAAAAAAATACATTAAAAAAGACAAAAAATTTTAGCATG
AAGTTGCTTTCTGTAACAACTCAAAGCCGTAACCCTGTTTTAGTGCCAGATACAAGTCTCTCCCGTGATGCTAGACAAAAAATTATTTTTCTTTGCTTTC
ACCAACATGGAGTTTGTGGGGGTGGGTCCAGTTATACATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGGATTTATCTCATTTTTAATCACAGGAT
AGTTTGGGGTTTATTCCTATTATTATTCATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCATTTGCTAAAGTTGAAAGTTGAAACTA
ACTATAATAGTTTGAAACATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATGTTTGTCTTTCTTACCCAAAGTAAAGA
TCCCCTGATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACACAGATATCTAAATCAGTTTTTTTCCAAGACTCCAAC
ATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAATACTGTTCTGACTGTATATACAGTCTAGAACTCACAAATCAATTAG
TTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATGAAATAGTCAATGGCCTGATTAAGGCAAAGAGCTACCAGGCTAGATGGACACTTTTT
AAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGCTGGTAGGTTGGATCTGAACCATTAAAATCAAATGGTCCACTAGGCGTATGATCTCTTTGAGCCAAA
TCAGTTCCTGAATATAAAGGAGGAAATGATGAGGATGTACTGAGGCAACGGGGAAGTATAGAAACATCCAAGACAAAAGCCAAGGGATGCAAAGGCAGAG
ACACAGGTGCTTTTTGGTGACCCAGTGGATATGGCAACCAGTGTAACTGCCATACAAGAAACCCTAGGAGCAAACCCACACCACTCATTCTCAGCTAAGA
GATTTTACACAGGCAAACGTGTCTTAAACCATCTATAAATCAGTTATTTTATATGACAGTCAAAACCTTAGAAACCTTAGGATCATTATATCTATTTTCT
GCCTATTAATTGCTGTGAGGTTTGATTTGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCAGAAAATAGAAGAAAGGTGTGTGGAGA
CTTAGGGTATTTTATTACATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTCATTAGAAAAGTTTTAACCTGTGAAAT
AAGTATTTTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCATACTAGAAGTCAGTTTATTACAAATACATGTCAAAAA
TAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTATTTCTAATCACAACAAAATTATAATGAATAAATGTTCTTGCTTTGT
ATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGATCGTTTGTACCAGTAAAAGAGAGAAACACACAGGTTAAATATCTTCTTGTGGGGTTA
AGGGGTAGAACCTATCTTGCCTTCACTCTCAAGATAACGACTCAAATTAAGCTTTTTGAGCACCACTCTTGTGGGGACACACATACGCTGATCTAGGAAT
GAAATCTTCGTGGTCTCAATTCTAGATCTACTATGCCAGTTTCTCTCTGGCTTTAGCCTTTGAGAACCTGTATAAGAATACGTAAGTAATCCAGAGCTGT
GAAGAGTTTAAAGGCCAACTTCTCCAGTGAACTCAACCTCTGGGTCACTTGCAACCAGAAATTGGATACCTCATAATGATGCAGGAAAGACCCGAGTTCA
TGATGAGTTTCAAAGGCCACGTTCATTTAGGAACCAACTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTGATGGGCTGACATCCCACCTACAAGTA
TGACACCTGTGTAACACCAGCTAGGTACGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTACTGATTGTAGTGACCTTCTCCACACA
CACACACACACACACACACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATTCCATCAGTATTTTATTAAGGAAATAA
CCTGAATGTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAATAAGGAAAATAAACTACTCATGGTCTAAATACTAGAG
ATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTGACGTGCTAAAATAAGCATTGATGTTTTGAGTTTTTTTACACCTAGG
ATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAGGAAAAAGCTTATTTTCAAACTCAGAAAATAAAATGTCAATCATAAAAATCTACTTC
AACTTTAGCAAAAAGAAAAAAAAATCAACAAAAAGTATACTCTGTATGCTGGGATTCCGAGGTTCCAACACACTGTTACAAATCTGTGGGGGGTTTCTTT
CTTCTGATAATTCTAGAGCCTGTTACCATAGAAAGGCATTTCTTCAATGGCTGGTTGTAGTTAGTTCATGTTTTTCAATCAAATTTGCAAATGTATTTGT
TGCTGTATAGTGATTGTTTTGCAAAATAAAATTGCTTGTCACCT
  • refseq_MAP2.F3 (forward primer)
  • refseq_MAP2.R3 (reverse primer)
  • Single exon skipping

Frame 0

SLGRALGLRGLWAAAAAAAASSLPLLPFRFFLF
LLLLFPPPPLLPLTLLPLSFFSGGR*VRERWQSR
PRVHPVSAPRFY*SNPKYLITSGWN*DSSACL*
PRKH*LGATHSEN*KKEARKYYQPFENTTQRTL
YFTTSLNSCRRNNKALKNGR*TER*SKGTSLDLS
TANRGICTLTST*D*GSRRSRGRTCPKRQWIPI
QGG*RGCLWRAWVTGHLFKYQREWDQRRADLS*
QRNSRGGVCKDSSSSHC*GCSSPER*TRERSST*
RPDCSSAFSS*RNS*SASFSTPITCLRTDCHSG
GSSRWGISSGSQCI*TGKGQSL*FYLVKDSCFT
G*HKVPKIQLSLP*HD*KGYIF*QFINTAHLSRL
HRPFAILKIREQGRSNQEPRKALFSPKTFLHSP
SSARCVRRQR*EFLLSQQFYLFFSTADHQVRAN
SQSREEWYLNTHYPWVYCHHSWHPTKLFFTHTRH
SWNP*LSQDPSHTRNPQVCHLGAE*EEGRHHTY
SSKISCDSQAASAY*PTTARPEECQIQNRINRQ
HQIPA*RGAG*DFKQEDRF*QSSVQMWFQG*HQT
FGWGRKCTNCYQENRPKPCDIQMWLSEEHPPQA
RWRTCEN*ECKTRFQRKGPS*SWFS**CSSCTW
RW*CQD*QPKVELQRAC*SPCGPWG*DHYTVPRQ
IQRGITPTTQQCLLVWKHQPARISSACHFG*GC
HCCTR*AGLVNISHLALK**YLGMSSWQEWALS
SCYIHSL*TIK*IISSPNCSNCYNFLFKK*IVHA
EIDLISICNRKTLALHGFNWTIIFALLCFAWSI
IILKIAFLPFMCLKAIHYILKALLKSKLLISLF
CF*VRR*KLPIVTYFRLN*TKESDCRKGRACKK*
VFLKCYFV*MGRKIQLSY*HLGPG*LYQSMSVQ
*II*LIKK*LQSI*AVVEEVV*KCIH*E*CTFI
RMDSCLIRMSVDQLDLCPHYQFHTPFPSV*YSII
DINIYIFLCGHL*YFLIYLNIILLYSQYLCLLH
PLVLQF*ICESRC*QGSLPI*KKYIKKDKKF*H
EVAFCNNSKP*PCFSARYKSLP*C*TKNYFSLLS
PTWSLWGWVQLYMKGFTDCWFKIMDLSHF*SQD
SLGFIPIIIHETDLRFFLYFSFFFHLLKLKVET
NYNSLKHVFSFFQIVSVY*IL**KMFVFLTQSKD
PLIRKKKYNTLGSYSYKTLETQISKSVFFQDSN
IALCKVTHCDLVLFISR*YCSDCIYSLELTNQL
VPLTNHSS*TYK*GMK*SMA*LRQRATRLDGHFL
KILSVLFLAQGW*VGSEPLKSNGPLGV*SL*AK
SVPEYKGGNDEDVLRQRGSIETSKTKAKGCKGR
DTGAFW*PSGYGNQCNCHTRNPRSKPTPLILS*E
ILHRQTCLKPSINQLFYMTVKTLETLGSLYLFS
AY*LL*GLI*PIWAIYSSASLEVHQKIEERCVE
T*GILLHVFIVLNSD*ISLERS*QLIRKVLTCEI
SIFLNIL*SFYIS*H*VNILHTRSQFITNTCQK
*RLYKAPNY*IWH*NKCLFLITTKL**INVLAL
YGNTILY*S*QKGTDRLYQ*KRETHRLNIFLWG*
GVEPILPSLSR*RLKLSFLSTTLVGTHIR*SRN
EIFVVSILDLLCQFLSGFSL*EPV*EYVSNPEL
*RV*RPTSPVNSTSGSLATRNWIPHNDAGKTRVH
DEFQRPRSFRNQLSLDLPAEFQQRDGLTSHLQV
*HLCNTS*VRLEKAEERMPLNGRMY*L**PSPH
THTHTHTHTPTVIQQAWNNQPIYNIPSVFY*GNN
LNVVDFDIAAITVFFYFSSHNKENKLLMV*ILE
IK*IHGLVRKF*AFLQRLTC*NKH*CFEFFYT*
DF*LGCVGEGQDSLQEKAYFQTQKIKCQS*KSTS
TLAKRKKNQQKVYSVCWDSEVPTHCYKSVGGFF
LLIILEPVTIERHFFNGWL*LVHVFQSNLQMYL
LLYSDCFAK*NCLSP

Frame 1

VWGGRSGCAGSGQQQQQQQHPLFLYFPSASFSS
FSFFFPPLPFFP*PFYPSPFSPEGAKSVSGGSR
DRGCIQFLRPDFIDLIQSIL*LLAGIKILQLVSN
RGSIDWELLIQKIKRKKPENIINPLRTRHNELY
ILPLP*IVAGEITRH*RMADERKDEAKAPHWTS
APLTEASAHSHPPEIKDQGGAGEGLVRSANGFPY
REDEEGAFGEHGSQGTYSNTKENGINGELTSAD
RETAEEVSARIVQVVTAEAVAVLKGEQEKEAQH
KDQTAALPLAAEETANLPPSPPPSPASEQTVTVE
EAAGGESALAPSVFKQAKDKVSNSTLSKIPALQ
GSTKSPRYSSACPSTTKRATFSDSLLIQPTSAG
STDRLPYSKSGNKDGVTKSPEKRSSLPRPSSILP
PRRGVSGDRDENSFSLNSSISSSARRTTRSEPI
RRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPG
TPGTPSYPRTPHTPGTPKSAILVPSEKKVAIIRT
PPKSPATPKQLRLINQPLPDLKNVKSKIGSTDN
IKYQPKGGQVRILNKKIDFSKVQSRCGSKDNIK
HSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRP
GGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPG
GGNVKIDSQKLNFREHAKARVDHGAEIITQSPG
RSSVASPRRLSNVSSSGSINLLESPQLATLAEDV
TAALAKQGL*IFLI*H*NNNI*A*ALGRSGL*A
VVIFILYKP*NK*SHPQTVVIVTIFYLKNE*YM
QKLT*FPFATGRHWLYMGSIGQLFLLCSVLHGVL
LF*KLHFYLSCA*RLSTTF*RPC*NPSCSFHYS
VSE*EDKNCPL*LISG*IKPRSLIAGREEHVRN
KFF*SVILYKWEERFN*VINIWDLDNYIRVCQSN
KLFN*LKNSCKAFELWLRKWCKSASIRNDALSL
GWTRV*LECQLIS*ICVHTTSFTPPFHLFDTVL
*I*IYIYFSVAICDTSSYT*ILYFFIHSICVSCT
LWCCNFRYVKVDVSRVLSLFKKNTLKKTKNFSM
KLLSVTTQSRNPVLVPDTSLSRDARQKIIFLCF
HQHGVCGGGSSYT*KGLQIVGLRLWIYLIFNHRI
VWGLFLLLFMKPT*DFFFIFLFFSIC*S*KLKL
TIIV*NMFSHFSK*YLFIKFSNRRCLSFLPKVK
IP*SERKNTILWEAIAIKHLRHRYLNQFFSKTPT
LHSVK*HTVI*YYLSVDNTVLTVYTV*NSQIN*
FLSQIIHLRLTNKE*NSQWPD*GKELPG*MDTF
*KFYLFFFLLRAGRLDLNH*NQMVH*AYDLFEPN
QFLNIKEEMMRMY*GNGEV*KHPRQKPRDAKAE
TQVLFGDPVDMATSVTAIQETLGANPHHSFSAK
RFYTGKRVLNHL*ISYFI*QSKP*KP*DHYIYFL
PINCCEV*FDQSGQFIHQLPLKCTRK*KKGVWR
LRVFYYMFS*S*IVIKFL*KEVNSSLEKF*PVK
*VFFSTFFKVFI*VNTR*TFCILEVSLLQIHVKN
KDYTRHQTTRFGIKTNVYF*SQQNYNE*MFLLC
MEIQFFIKVNRKELIVCTSKREKHTG*ISSCGV
KG*NLSCLHSQDNDSN*AF*APLLWGHTYADLGM
KSSWSQF*IYYASFSLALAFENLYKNT*VIQSC
EEFKGQLLQ*TQPLGHLQPEIGYLIMMQERPEF
MMSFKGHVHLGTNSLWIYLLSSSSVMG*HPTYKY
DTCVTPARYGWRRLKRECH*MEECTDCSDLLHT
HTHTHTHTHLQ*YSKRGIISQYITFHQYFIKEI
T*MWLILT*LQLQFSSIFQATIRKINYSWSKY*R
*SRFMAW*GNFKHSFKD*RAKISIDVLSFFTPR
IFSLGV*VKAKTLCRKKLIFKLRK*NVNHKNLL
QL*QKEKKINKKYTLYAGIPRFQHTVTNLWGVSF
F**F*SLLP*KGISSMAGCS*FMFFNQICKCIC
CCIVIVLQNKIACH

Frame 2

SGAGARAARALGSSSSSSSILSSFTSLPLLSLP
SPSFSPPSPSSPNPSTPLLFLRRALSP*AVAVA
TAGASSFCAQILLI*SKVSYNFWLELRFFSLSL
TEEALIGSYSFRKLKERSQKILSTL*EHDTTNFI
FYHFLE*LQEK*QGIEEWQMNGKMKQRHLTGPQ
HR*QRHLHTHIHLRLRIKAEQGKDLSEAPMDSH
TGRMKRVPLESMGHRAPIQIPKRMGSTES*PQLT
EKQQRRCLQG*FK*SLLRL*QS*KVNKRKKLNI
KTRLQLCL*QLKKQLICLLLHPHHLPQNRLSQW
RKQQVGNQLWLPVYLNRQRTKSLILPCQRFLLYR
VAQSPQDTAQPALARLKGLHFLTVY*YSPPQQA
PQTVCHTQNQGTRTE*PRAQKSALLSQDLPPFS
LLGEVCQETEMRIPSLSTVLSLLQHGGPPGQSQF
AEQGRVVPQHPLPLGLLPSLLAPHQVILHAHQA
LLEPLAIPGPLTHQEPPSLPSWCRVRRRSPSYV
LLQNLLRLPSSFGLLTNHCQT*RMSNPKSDQQTT
SNTSLKGGRLGF*TRRSILAKFSPDVVPRITSN
IRLGAEMYKLLPRK*T*AM*HPNVAL*RTSATG
QVADV*KLRV*N*ISKKRPKLKLVLLIMLIMYLE
VVMSRLTAKS*TSESMLKPVWTMGLRSLHSPQA
DPAWHHPDDSAMSPRLEASTCSNLLSLPLWLRM
SLLHSLSRACEYFSFSIEIIIFRHELLAGVGSEQ
LLYSFFINHKINNLIPKL**LLQFSI*KMNSTC
RN*PDFHLQQEDTGFTWVQLDNYFCSALFCMEY
YYFKNCIFTFHVPEGYPLHSEGLVKIQAAHFTIL
FLSEKIKTAHCNLFQVKLNQGV*LQEGKSM*EI
SFFKVLFCINGKKDSIKLLTFGTWIIISEYVSP
INYLTN*KIVAKHLSCG*GSGVKVHPLGMMHFH*
DGLVSD*NVS*SARFVSTLPVSHPLSICLIQYY
RYKYIYISLWPFVILPHILEYYTSLFTVSVSPA
PFGVAILDM*K*MLAGFSPYLKKIH*KRQKILA*
SCFL*QLKAVTLF*CQIQVSPVMLDKKLFFFAF
TNMEFVGVGPVIHERVYRLLV*DYGFISFLITG
*FGVYSYYYS*NRLKIFSLFFFFFPFAKVES*N*
L**FETCFLIFPNSICLLNSLIEDVCLSYPK*R
SPDQKEKIQYFGKL*L*NT*DTDI*ISFFPRLQ
HCTL*SNTL*SSIIYQ*IILF*LYIQSRTHKSIS
SSHKSFILDLQIRNEIVNGLIKAKSYQARWTLF
KNFICSFSCSGLVGWI*TIKIKWSTRRMISLSQ
ISS*I*RRK**GCTEATGKYRNIQDKSQGMQRQR
HRCFLVTQWIWQPV*LPYKKP*EQTHTTHSQLR
DFTQANVS*TIYKSVILYDSQNLRNLRIIISIF
CLLIAVRFDLTNLGNLFISFP*SAPENRRKVCGD
LGYFITCFHSLK**LNFSRKKLTAH*KSFNL*N
KYFSQHSLKFLYKLTLGKHSAY*KSVYYKYMSK
IKIIQGTKLLDLALKQMFISNHNKIIMNKCSCFV
WKYNSLLKLTERN*SFVPVKERNTQVKYLLVGL
RGRTYLAFTLKITTQIKLFEHHSCGDTHTLI*E
*NLRGLNSRSTMPVSLWL*PLRTCIRIRK*SRAV
KSLKANFSSELNLWVTCNQKLDTS**CRKDPSS
**VSKATFI*EPTLSGFTC*VPAA*WADIPPTS
MTPV*HQLGTAGEG*RENAIKWKNVLIVVTFSTH
THTHTHTHTYSNTASVE*SANI*HSISILLRK*
PECG*F*HSCNYSFLLFFKPQ*GK*TTHGLNTR
DKVDSWLGKEILSIPSKIDVLK*ALMF*VFLHLG
FLAWVCR*RPRLSAGKSLFSNSENKMSIIKIYF
NFSKKKKKSTKSILCMLGFRGSNTLLQICGGFL
SSDNSRACYHRKAFLQWLVVVSSCFSIKFANVFV
AV**LFCKIKLLVT

Sequence NM_031847

GGGATAATGCTCCCGGAGAAGGATTCTGCAGCAGTTCTCAAAGGCTAGACTTGAGTGGTATTGCTGCATATGCGCTGATTCTTCAGCTTGTCTCTAACCG
AGGAAGCATTGATTGGGAGCTACTCATTCAGAAAATTAAAAGAAAGAAGCCAGAAAATATTATCAACCCTTTGAGAACACGACACAACGAACTTTATATT
TTACCACTTCCTTGAATAGTTGCAGGAGAAATAACAAGGCATTGAAGAATGGCAGATGAACGGAAAGATGAAGCAAAGGCACCTCACTGGACCTCAGCAC
CGCTAACAGAGGCATCTGCACACTCACATCCACCTGAGATTAAGGATCAAGGCGGAGCAGGGGAAGGACTTGTCCGAAGCGCCAATGGATTCCCATACAG
GGAGGATGAAGAGGGTGCCTTTGGAGAGCATGGGTCACAGGGCACCTATTCAAATACCAAAGAGAATGGGATCAACGGAGAGCTGACCTCAGCTGACAGA
GAAACAGCAGAGGAGGTGTCTGCAAGGATAGTTCAAGTAGTCACTGCTGAGGCTGTAGCAGTCCTGAAAGGTGAACAAGAGAAAGAAGCTCAACATAAAG
ACCAGACTGCAGCTCTGCCTTTAGCAGCTGAAGAAACAGCTAATCTGCCTCCTTCTCCACCCCCATCACCTGCCTCAGAACAGACTGTCACAGTGGAGGA
AGCAGCAGGTGGGGAATCAGCTCTGGCTCCCAGTGTATTTAAACAGGCAAAGGACAAAGTCTCTGACGGAGTAACCAAGAGCCCAGAAAAGCGCTCTTCT
CTCCCAAGACCTTCCTCCATTCTCCCTCCTCGGCGAGGTGTGTCAGGAGACAGAGATGAGAATTCCTTCTCTCTCAACAGTTCTATCTCTTCTTCAGCAC
GGCGGACCACCAGGTCAGAGCCAATTCGCAGAGCAGGGAAGAGTGGTACCTCAACACCCACTACCCCTGGGTCTACTGCCATCACTCCTGGCACCCCACC
AAGTTATTCTTCACGCACACCAGGCACTCCTGGAACCCCTAGCTATCCCAGGACCCCTCACACACCAGGAACCCCCAAGTCTGCCATCTTGGTGCCGAGT
GAGAAGAAGGTCGCCATCATACGTACTCCTCCAAAATCTCCTGCGACTCCCAAGCAGCTTCGGCTTATTAACCAACCACTGCCAGACCTGAAGAATGTCA
AATCCAAAATCGGATCAACAGACAACATCAAATACCAGCCTAAAGGGGGGCAGGTTAGGATTTTAAACAAGAAGATCGATTTTAGCAAAGTTCAGTCCAG
ATGTGGTTCCAAGGATAACATCAAACATTCGGCTGGGGGCGGAAATGTACAAATTGTTACCAAGAAAATAGACCTAAGCCATGTGACATCCAAATGTGGC
TCTCTGAAGAACATCCGCCACAGGCCAGGTGGCGGACGTGTGAAAATTGAGAGTGTAAAACTAGATTTCAAAGAAAAGGCCCAAGCTAAAGTTGGTTCTC
TTGATAATGCTCATCATGTACCTGGAGGTGGTAATGTCAAGATTGACAGCCAAAAGTTGAACTTCAGAGAGCATGCTAAAGCCCGTGTGGACCATGGGGC
TGAGATCATTACACAGTCCCCAGGCAGATCCAGCGTGGCATCACCCCGACGACTCAGCAATGTCTCCTCGTCTGGAAGCATCAACCTGCTCGAATCTCCT
CAGCTTGCCACTTTGGCTGAGGATGTCACTGCTGCACTCGCTAAGCAGGGCTTGTGAATATTTCTCATTTAGCATTGAAATAATAATATTTAGGCATGAG
CTCTTGGCAGGAGTGGGCTCTGAGCAGTTGTTATATTCATTCTTTATAAACCATAAAATAAATAATCTCATCCCCAAACTGTAGTAATTGTTACAATTTT
CTATTTAAAAAATGAATAGTACATGCAGAAATTGACCTGATTTCCATTTGCAACAGGAAGACACTGGCTTTACATGGGTTCAATTGGACAATTATTTTTG
CTCTGCTCTGTTTTGCATGGAGTATTATTATTTTAAAAATTGCATTTTTACCTTTCATGTGCCTGAAGGCTATCCACTACATTCTGAAGGCCTTGTTAAA
ATCCAAGCTGCTCATTTCACTATTCTGTTTCTGAGTGAGAAGATAAAAACTGCCCATTGTAACTTATTTCAGGTTAAATTAAACCAAGGAGTCTGATTGC
AGGAAGGGAAGAGCATGTAAGAAATAAGTTTTTTTAAAGTGTTATTTTGTATAAATGGGAAGAAAGATTCAATTAAGTTATTAACATTTGGGACCTGGAT
AATTATATCAGAGTATGTCAGTCCAATAAATTATTTAACTAATTAAAAAATAGTTGCAAAGCATTTGAGCTGTGGTTGAGGAAGTGGTGTAAAAGTGCAT
CCATTAGGAATGATGCACTTTCATTAGGATGGACTCGTGTCTGATTAGAATGTCAGTTGATCAGCTAGATTTGTGTCCACACTACCAGTTTCACACCCCC
TTTCCATCTGTTTGATACAGTATTATAGATATAAATATATATATATTTCTCTGTGGCCATTTGTGATACTTCCTCATATACTTGAATATTATACTTCTTT
ATTCACAGTATCTGTGTCTCCTGCACCCTTTGGTGTTGCAATTTTAGATATGTGAAAGTAGATGTTAGCAGGGTTCTCTCCCTATTTAAAAAAAATACAT
TAAAAAAGACAAAAAATTTTAGCATGAAGTTGCTTTCTGTAACAACTCAAAGCCGTAACCCTGTTTTAGTGCCAGATACAAGTCTCTCCCGTGATGCTAG
ACAAAAAATTATTTTTCTTTGCTTTCACCAACATGGAGTTTGTGGGGGTGGGTCCAGTTATACATGAAAGGGTTTACAGATTGTTGGTTTAAGATTATGG
ATTTATCTCATTTTTAATCACAGGATAGTTTGGGGTTTATTCCTATTATTATTCATGAAACCGACTTAAGATTTTTTCTTTATTTTTCTTTTTTTTTCCA
TTTGCTAAAGTTGAAAGTTGAAACTAACTATAATAGTTTGAAACATGTTTTCTCATTTTTCCAAATAGTATCTGTTTATTAAATTCTCTAATAGAAGATG
TTTGTCTTTCTTACCCAAAGTAAAGATCCCCTGATCAGAAAGAAAAAATACAATACTTTGGGAAGCTATAGCTATAAAACACTTGAGACACAGATATCTA
AATCAGTTTTTTTCCAAGACTCCAACATTGCACTCTGTAAAGTAACACACTGTGATCTAGTATTATTTATCAGTAGATAATACTGTTCTGACTGTATATA
CAGTCTAGAACTCACAAATCAATTAGTTCCTCTCACAAATCATTCATCTTAGACTTACAAATAAGGAATGAAATAGTCAATGGCCTGATTAAGGCAAAGA
GCTACCAGGCTAGATGGACACTTTTTAAAAATTTTATCTGTTCTTTTTCTTGCTCAGGGCTGGTAGGTTGGATCTGAACCATTAAAATCAAATGGTCCAC
TAGGCGTATGATCTCTTTGAGCCAAATCAGTTCCTGAATATAAAGGAGGAAATGATGAGGATGTACTGAGGCAACGGGGAAGTATAGAAACATCCAAGAC
AAAAGCCAAGGGATGCAAAGGCAGAGACACAGGTGCTTTTTGGTGACCCAGTGGATATGGCAACCAGTGTAACTGCCATACAAGAAACCCTAGGAGCAAA
CCCACACCACTCATTCTCAGCTAAGAGATTTTACACAGGCAAACGTGTCTTAAACCATCTATAAATCAGTTATTTTATATGACAGTCAAAACCTTAGAAA
CCTTAGGATCATTATATCTATTTTCTGCCTATTAATTGCTGTGAGGTTTGATTTGACCAATCTGGGCAATTTATTCATCAGCTTCCCTTGAAGTGCACCA
GAAAATAGAAGAAAGGTGTGTGGAGACTTAGGGTATTTTATTACATGTTTTCATAGTCTTAAATAGTGATTAAATTTCTCTAGAAAGAAGTTAACAGCTC
ATTAGAAAAGTTTTAACCTGTGAAATAAGTATTTTTCTCAACATTCTTTAAAGTTTTTATATAAGTTAACACTAGGTAAACATTCTGCATACTAGAAGTC
AGTTTATTACAAATACATGTCAAAAATAAAGATTATACAAGGCACCAAACTACTAGATTTGGCATTAAAACAAATGTTTATTTCTAATCACAACAAAATT
ATAATGAATAAATGTTCTTGCTTTGTATGGAAATACAATTCTTTATTAAAGTTAACAGAAAGGAACTGATCGTTTGTACCAGTAAAAGAGAGAAACACAC
AGGTTAAATATCTTCTTGTGGGGTTAAGGGGTAGAACCTATCTTGCCTTCACTCTCAAGATAACGACTCAAATTAAGCTTTTTGAGCACCACTCTTGTGG
GGACACACATACGCTGATCTAGGAATGAAATCTTCGTGGTCTCAATTCTAGATCTACTATGCCAGTTTCTCTCTGGCTTTAGCCTTTGAGAACCTGTATA
AGAATACGTAAGTAATCCAGAGCTGTGAAGAGTTTAAAGGCCAACTTCTCCAGTGAACTCAACCTCTGGGTCACTTGCAACCAGAAATTGGATACCTCAT
AATGATGCAGGAAAGACCCGAGTTCATGATGAGTTTCAAAGGCCACGTTCATTTAGGAACCAACTCTCTCTGGATTTACCTGCTGAGTTCCAGCAGCGTG
ATGGGCTGACATCCCACCTACAAGTATGACACCTGTGTAACACCAGCTAGGTACGGCTGGAGAAGGCTGAAGAGAGAATGCCATTAAATGGAAGAATGTA
CTGATTGTAGTGACCTTCTCCACACACACACACACACACACACACACACACACCTACAGTAATACAGCAAGCGTGGAATAATCAGCCAATATATAACATT
CCATCAGTATTTTATTAAGGAAATAACCTGAATGTGGTTGATTTTGACATAGCTGCAATTACAGTTTTCTTCTATTTTTCAAGCCACAATAAGGAAAATA
AACTACTCATGGTCTAAATACTAGAGATAAAGTAGATTCATGGCTTGGTAAGGAAATTTTAAGCATTCCTTCAAAGATTGACGTGCTAAAATAAGCATTG
ATGTTTTGAGTTTTTTTACACCTAGGATTTTTAGCTTGGGTGTGTAGGTGAAGGCCAAGACTCTCTGCAGGAAAAAGCTTATTTTCAAACTCAGAAAATA
AAATGTCAATCATAAAAATCTACTTCAACTTTAGCAAAAAGAAAAAAAAATCAACAAAAAGTATACTCTGTATGCTGGGATTCCGAGGTTCCAACACACT
GTTACAAATCTGTGGGGGGTTTCTTTCTTCTGATAATTCTAGAGCCTGTTACCATAGAAAGGCATTTCTTCAATGGCTGGTTGTAGTTAGTTCATGTTTT
TCAATCAAATTTGCAAATGTATTTGTTGCTGTATAGTGATTGTTTTGCAAAATAAAATTGCTTGTCACCT
  • refseq_MAP2.F3 (forward primer)
  • refseq_MAP2.R3 (reverse primer)
  • Single exon skipping

Frame 0

GIMLPEKDSAAVLKG*T*VVLLHMR*FFSLSLT
EEALIGSYSFRKLKERSQKILSTL*EHDTTNFIF
YHFLE*LQEK*QGIEEWQMNGKMKQRHLTGPQH
R*QRHLHTHIHLRLRIKAEQGKDLSEAPMDSHT
GRMKRVPLESMGHRAPIQIPKRMGSTES*PQLTE
KQQRRCLQG*FK*SLLRL*QS*KVNKRKKLNIK
TRLQLCL*QLKKQLICLLLHPHHLPQNRLSQWR
KQQVGNQLWLPVYLNRQRTKSLTE*PRAQKSALL
SQDLPPFSLLGEVCQETEMRIPSLSTVLSLLQH
GGPPGQSQFAEQGRVVPQHPLPLGLLPSLLAPH
QVILHAHQALLEPLAIPGPLTHQEPPSLPSWCRV
RRRSPSYVLLQNLLRLPSSFGLLTNHCQT*RMS
NPKSDQQTTSNTSLKGGRLGF*TRRSILAKFSP
DVVPRITSNIRLGAEMYKLLPRK*T*AM*HPNVA
L*RTSATGQVADV*KLRV*N*ISKKRPKLKLVL
LIMLIMYLEVVMSRLTAKS*TSESMLKPVWTMG
LRSLHSPQADPAWHHPDDSAMSPRLEASTCSNLL
SLPLWLRMSLLHSLSRACEYFSFSIEIIIFRHE
LLAGVGSEQLLYSFFINHKINNLIPKL**LLQF
SI*KMNSTCRN*PDFHLQQEDTGFTWVQLDNYFC
SALFCMEYYYFKNCIFTFHVPEGYPLHSEGLVK
IQAAHFTILFLSEKIKTAHCNLFQVKLNQGV*L
QEGKSM*EISFFKVLFCINGKKDSIKLLTFGTWI
IISEYVSPINYLTN*KIVAKHLSCG*GSGVKVH
PLGMMHFH*DGLVSD*NVS*SARFVSTLPVSHP
LSICLIQYYRYKYIYISLWPFVILPHILEYYTSL
FTVSVSPAPFGVAILDM*K*MLAGFSPYLKKIH
*KRQKILA*SCFL*QLKAVTLF*CQIQVSPVML
DKKLFFFAFTNMEFVGVGPVIHERVYRLLV*DYG
FISFLITG*FGVYSYYYS*NRLKIFSLFFFFFP
FAKVES*N*L**FETCFLIFPNSICLLNSLIED
VCLSYPK*RSPDQKEKIQYFGKL*L*NT*DTDI*
ISFFPRLQHCTL*SNTL*SSIIYQ*IILF*LYI
QSRTHKSISSSHKSFILDLQIRNEIVNGLIKAK
SYQARWTLFKNFICSFSCSGLVGWI*TIKIKWST
RRMISLSQISS*I*RRK**GCTEATGKYRNIQD
KSQGMQRQRHRCFLVTQWIWQPV*LPYKKP*EQ
THTTHSQLRDFTQANVS*TIYKSVILYDSQNLRN
LRIIISIFCLLIAVRFDLTNLGNLFISFP*SAP
ENRRKVCGDLGYFITCFHSLK**LNFSRKKLTA
H*KSFNL*NKYFSQHSLKFLYKLTLGKHSAY*KS
VYYKYMSKIKIIQGTKLLDLALKQMFISNHNKI
IMNKCSCFVWKYNSLLKLTERN*SFVPVKERNT
QVKYLLVGLRGRTYLAFTLKITTQIKLFEHHSCG
DTHTLI*E*NLRGLNSRSTMPVSLWL*PLRTCI
RIRK*SRAVKSLKANFSSELNLWVTCNQKLDTS
**CRKDPSS**VSKATFI*EPTLSGFTC*VPAA*
WADIPPTSMTPV*HQLGTAGEG*RENAIKWKNV
LIVVTFSTHTHTHTHTHTYSNTASVE*SANI*H
SISILLRK*PECG*F*HSCNYSFLLFFKPQ*GK*
TTHGLNTRDKVDSWLGKEILSIPSKIDVLK*AL
MF*VFLHLGFLAWVCR*RPRLSAGKSLFSNSEN
KMSIIKIYFNFSKKKKKSTKSILCMLGFRGSNTL
LQICGGFLSSDNSRACYHRKAFLQWLVVVSSCF
SIKFANVFVAV**LFCKIKLLVT

Frame 1

G*CSRRRILQQFSKARLEWYCCICADSSACL*P
RKH*LGATHSEN*KKEARKYYQPFENTTQRTLY
FTTSLNSCRRNNKALKNGR*TER*SKGTSLDLST
ANRGICTLTST*D*GSRRSRGRTCPKRQWIPIQ
GG*RGCLWRAWVTGHLFKYQREWDQRRADLS*Q
RNSRGGVCKDSSSSHC*GCSSPER*TRERSST*R
PDCSSAFSS*RNS*SASFSTPITCLRTDCHSGG
SSRWGISSGSQCI*TGKGQSL*RSNQEPRKALF
SPKTFLHSPSSARCVRRQR*EFLLSQQFYLFFST
ADHQVRANSQSREEWYLNTHYPWVYCHHSWHPT
KLFFTHTRHSWNP*LSQDPSHTRNPQVCHLGAE
*EEGRHHTYSSKISCDSQAASAY*PTTARPEECQ
IQNRINRQHQIPA*RGAG*DFKQEDRF*QSSVQ
MWFQG*HQTFGWGRKCTNCYQENRPKPCDIQMW
LSEEHPPQARWRTCEN*ECKTRFQRKGPS*SWFS
**CSSCTWRW*CQD*QPKVELQRAC*SPCGPWG
*DHYTVPRQIQRGITPTTQQCLLVWKHQPARIS
SACHFG*GCHCCTR*AGLVNISHLALK**YLGMS
SWQEWALSSCYIHSL*TIK*IISSPNCSNCYNF
LFKK*IVHAEIDLISICNRKTLALHGFNWTIIF
ALLCFAWSIIILKIAFLPFMCLKAIHYILKALLK
SKLLISLFCF*VRR*KLPIVTYFRLN*TKESDC
RKGRACKK*VFLKCYFV*MGRKIQLSY*HLGPG
*LYQSMSVQ*II*LIKK*LQSI*AVVEEVV*KCI
H*E*CTFIRMDSCLIRMSVDQLDLCPHYQFHTP
FPSV*YSIIDINIYIFLCGHL*YFLIYLNIILL
YSQYLCLLHPLVLQF*ICESRC*QGSLPI*KKYI
KKDKKF*HEVAFCNNSKP*PCFSARYKSLP*C*
TKNYFSLLSPTWSLWGWVQLYMKGFTDCWFKIM
DLSHF*SQDSLGFIPIIIHETDLRFFLYFSFFFH
LLKLKVETNYNSLKHVFSFFQIVSVY*IL**KM
FVFLTQSKDPLIRKKKYNTLGSYSYKTLETQIS
KSVFFQDSNIALCKVTHCDLVLFISR*YCSDCIY
SLELTNQLVPLTNHSS*TYK*GMK*SMA*LRQR
ATRLDGHFLKILSVLFLAQGW*VGSEPLKSNGP
LGV*SL*AKSVPEYKGGNDEDVLRQRGSIETSKT
KAKGCKGRDTGAFW*PSGYGNQCNCHTRNPRSK
PTPLILS*EILHRQTCLKPSINQLFYMTVKTLE
TLGSLYLFSAY*LL*GLI*PIWAIYSSASLEVHQ
KIEERCVET*GILLHVFIVLNSD*ISLERS*QL
IRKVLTCEISIFLNIL*SFYIS*H*VNILHTRS
QFITNTCQK*RLYKAPNY*IWH*NKCLFLITTKL
**INVLALYGNTILY*S*QKGTDRLYQ*KRETH
RLNIFLWG*GVEPILPSLSR*RLKLSFLSTTLV
GTHIR*SRNEIFVVSILDLLCQFLSGFSL*EPV*
EYVSNPEL*RV*RPTSPVNSTSGSLATRNWIPH
NDAGKTRVHDEFQRPRSFRNQLSLDLPAEFQQR
DGLTSHLQV*HLCNTS*VRLEKAEERMPLNGRMY
*L**PSPHTHTHTHTHTPTVIQQAWNNQPIYNI
PSVFY*GNNLNVVDFDIAAITVFFYFSSHNKEN
KLLMV*ILEIK*IHGLVRKF*AFLQRLTC*NKH*
CFEFFYT*DF*LGCVGEGQDSLQEKAYFQTQKI
KCQS*KSTSTLAKRKKNQQKVYSVCWDSEVPTH
CYKSVGGFFLLIILEPVTIERHFFNGWL*LVHVF
QSNLQMYLLLYSDCFAK*NCLSP

Frame 2

DNAPGEGFCSSSQRLDLSGIAAYALILQLVSNR
GSIDWELLIQKIKRKKPENIINPLRTRHNELYI
LPLP*IVAGEITRH*RMADERKDEAKAPHWTSA
PLTEASAHSHPPEIKDQGGAGEGLVRSANGFPYR
EDEEGAFGEHGSQGTYSNTKENGINGELTSADR
ETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHK
DQTAALPLAAEETANLPPSPPPSPASEQTVTVEE
AAGGESALAPSVFKQAKDKVSDGVTKSPEKRSS
LPRPSSILPPRRGVSGDRDENSFSLNSSISSSA
RRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPP
SYSSRTPGTPGTPSYPRTPHTPGTPKSAILVPS
EKKVAIIRTPPKSPATPKQLRLINQPLPDLKNV
KSKIGSTDNIKYQPKGGQVRILNKKIDFSKVQSR
CGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCG
SLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGS
LDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGA
EIITQSPGRSSVASPRRLSNVSSSGSINLLESP
QLATLAEDVTAALAKQGL*IFLI*H*NNNI*A*
ALGRSGL*AVVIFILYKP*NK*SHPQTVVIVTIF
YLKNE*YMQKLT*FPFATGRHWLYMGSIGQLFL
LCSVLHGVLLF*KLHFYLSCA*RLSTTF*RPC*
NPSCSFHYSVSE*EDKNCPL*LISG*IKPRSLIA
GREEHVRNKFF*SVILYKWEERFN*VINIWDLD
NYIRVCQSNKLFN*LKNSCKAFELWLRKWCKSA
SIRNDALSLGWTRV*LECQLIS*ICVHTTSFTPP
FHLFDTVL*I*IYIYFSVAICDTSSYT*ILYFF
IHSICVSCTLWCCNFRYVKVDVSRVLSLFKKNT
LKKTKNFSMKLLSVTTQSRNPVLVPDTSLSRDAR
QKIIFLCFHQHGVCGGGSSYT*KGLQIVGLRLW
IYLIFNHRIVWGLFLLLFMKPT*DFFFIFLFFS
IC*S*KLKLTIIV*NMFSHFSK*YLFIKFSNRRC
LSFLPKVKIP*SERKNTILWEAIAIKHLRHRYL
NQFFSKTPTLHSVK*HTVI*YYLSVDNTVLTVY
TV*NSQIN*FLSQIIHLRLTNKE*NSQWPD*GKE
LPG*MDTF*KFYLFFFLLRAGRLDLNH*NQMVH
*AYDLFEPNQFLNIKEEMMRMY*GNGEV*KHPR
QKPRDAKAETQVLFGDPVDMATSVTAIQETLGAN
PHHSFSAKRFYTGKRVLNHL*ISYFI*QSKP*K
P*DHYIYFLPINCCEV*FDQSGQFIHQLPLKCT
RK*KKGVWRLRVFYYMFS*S*IVIKFL*KEVNSS
LEKF*PVK*VFFSTFFKVFI*VNTR*TFCILEV
SLLQIHVKNKDYTRHQTTRFGIKTNVYF*SQQN
YNE*MFLLCMEIQFFIKVNRKELIVCTSKREKHT
G*ISSCGVKG*NLSCLHSQDNDSN*AF*APLLW
GHTYADLGMKSSWSQF*IYYASFSLALAFENLY
KNT*VIQSCEEFKGQLLQ*TQPLGHLQPEIGYLI
MMQERPEFMMSFKGHVHLGTNSLWIYLLSSSSV
MG*HPTYKYDTCVTPARYGWRRLKRECH*MEEC
TDCSDLLHTHTHTHTHTHLQ*YSKRGIISQYITF
HQYFIKEIT*MWLILT*LQLQFSSIFQATIRKI
NYSWSKY*R*SRFMAW*GNFKHSFKD*RAKISI
DVLSFFTPRIFSLGV*VKAKTLCRKKLIFKLRK*
NVNHKNLLQL*QKEKKINKKYTLYAGIPRFQHT
VTNLWGVSFF**F*SLLP*KGISSMAGCS*FMF
FNQICKCICCCIVIVLQNKIACH

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