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Sequences

Sequence NM_201544

TCCAAGGCTCCAGAGGCTGTGCAGGAGGCCGAGCTGGGTGGCGATCAGCGGCGGGTCCCTGTCCAAAACCCAGCAGAGCCGCCAGGGACGCCCCAGACAC AGAAGGCGGGGCGCGGGGAGGGTGGGGAGACCACAGCAGTGAGGCGCGCGAGCCGGGAAGTGAACGAGGACTGACTCCTGTCGCTTCCCGTAGCCGCCCA CGGACGCCAGAGCCGGGAACCCTGACGGCACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAACACCAGTCTTTGGGGCCAGTGCCTCAGT TTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCC TTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGC ATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAA AAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAG ATCGTGATTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTC TGGGCATTTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAG TAGAGAAAATGTTCCAAAGTCTGGCACGCCCCAGCTTAGGCTGCCATTCGCTGCAAGGTTGAACACCCCCATGGGCCCTGGACGAACTGTCGTCGTTAAA GGAGAAGTGAATGCAAATGCCAAAAGCTTTAATGTTGACCTACTAGCAGGAAAATCAAAGGATATTGCTCTACACTTGAACCCACGCCTGAATATTAAAG CATTTGTAAGAAATTCTTTTCTTCAGGAGTCCTGGGGAGAAGAAGAGAGAAATATTACCTCTTTCCCATTTAGTCCTGGGATGTACTTTGAGATGATAAT TTATTGTGATGTTAGAGAATTCAAGGTTGCAGTAAATGGCGTACACAGCCTGGAGTACAAACACAGATTTAAAGAGCTCAGCAGTATTGACACGCTGGAA ATTAATGGAGACATCCACTTACTGGAAGTAAGGAGCTGGTAGCCTACCTACACAGCTGCTACAAAAACCAAAATACAGAATGGCTTCTGTGATACTGGCC TTGCTGAAACGCATCTCACTGTCATTCTATTGTTTATATTGTTAAAATGAGCTTGTGCACCATTAGGTCCTGCTGGGTGTTCTCAGTCCTTGCCATGAAG TATGGTGGTGTCTAGCACTGAATGGGGAAACTGGGGGCAGCAACACTTATAGCCAGTTAAAGCCACTCTGCCCTCTCTCCTACTTTGGCTGACTCTTCAA GAATGCCATTCAACAAGTATTTATGGAGTACCTACTATAATACAGTAGCTAACATGTATTGAGCACAGATTTTTTTTGGTAAAACTGTGAAGAGCTAGGA TATATACTTGGTGAAACAAACCAGTATGTTCCCTGTTCTCTTGAGCTTCGACTCTTCTGTGCGCTACTGCTGCGCACTGCTTTTTCTACAGGCATTACAT CAACTCCTAAGGGGTCCTCTGGGATTAGTTATGCAGATATTAAATCACCCGAAGACACTAACTTACAGAAGACACAACTCCTTCCCCAGTGATCACTGTC ATAACCAGTGCTCTACCGTATCCCATCACTGAGGACTGATGTTGACTGACATCATTTTCTTTATCGTAATAAACATGTGGCTCTATTAGCTGCAAGCTTT ACCAAGTAATTGGCATGACATCTGAGCACAGAAATTAAGGCAAAAAACCAAAGCAAAACAAATACATGGTGCTGAAATTAACTTGATGCCAAGCCCAAGG CAGCTGATTTCTGTGTATTTGAACTTAGGGCAAATCAGAGTCTACACAGACGCCTACAGAAAGTTTCAGGAAGAGGCAAGATGCATTCAATTTGAAAGAT ATTTATGGGCAACAAAGTAAGGTCAGGATTAGACTTCAGGCATTCATAAGGCAGGCACTATCAGAAAGTGTACGCCAACTAAGGGACCCACAAAGCAGGC AGAGGTAATGCAGAAATCTGTTTTGTTCCCATGAAATCACCAATCAAGGCCTCCGTTCTTCTAAAGATTAGTCCATCATCATTAGCAACTGAGATCAAAG CACTCTTCCACTTTACGTGATTAAAATCAAACCTGTATCAGCAAGTTAAATGGTTCCATTTCTGTGATTTTTCTATTATTTGAGGGGAGTTGGCAGAAGT TCCATGTATATGGGATCTTTACAGGTCAGATCTTGTTACAGGAAATTTCAAAGGTTTGGGAGTGGGGAGGGAAAAAAGCTCAGTCAGTGAGGATCATTTT ATCACATTAGACTGGGGCAGAACTCTGCCAGGATTTAGGAATATTTTCAGAACAGATTTTAGATATTATTTCTATCCATATATTGAAAAGAATACCATTG TCAATCTTATTTTTTTAAAAGTACTCAGTGTAGAAATCGCTAGCCCTTAATTCTTTTCCAGCTTTTCATATTAATGTATGCAGAGTCTCACCAAGCTCAA AGACACTGGTTGGGGGTGGAGGGTGCCACAGGGAAAGCTGTAGAAGGCAAGAAGACTCGAGAATCCCCCAGAGTTAT

refseq_LGALS8.F2 (forward primer)
refseq_LGALS8.R2 (reverse primer)
Single exon skipping

Frame 0

SKAPEAVQEAELGGDQRRVPVQNPAEPPGTPQT QKAGRGEGGETTAVRRASREVNED*LLSLPVAAH GRQSREP*RHLAADKQPAPWSA*NTSLWGQCLS FNPGNL*MKLA*NLRSYTEETPIDKKLEKNDVV LKQPTEYHL*PGNPVCWHHS*SAGSWNFDCDTWA CS**RRQIPGGSAEWQQHETSSRCGLSFQSSFQ KGRLHCLQYFDK*KMGTGRDHL*HAFQKRKVF* DRDYGAEGQIPGGCKWKTYSALWPQDRPRENRHS GHLWQSEYSLNWF*LQLGLTKYPSI*SGTDRDK *RKCSKVWHAPA*AAIRCKVEHPHGPWTNCRR* RRSECKCQKL*C*PTSRKIKGYCSTLEPTPEY*S ICKKFFSSGVLGRRREKYYLFPI*SWDVL*DDN LL*C*RIQGCSKWRTQPGVQTQI*RAQQY*HAG N*WRHPLTGSKELVAYLHSCYKNQNTEWLL*YWP C*NASHCHSIVYIVKMSLCTIRSCWVFSVLAMK YGGV*H*MGKLGAATLIAS*SHSALSPTLADSS RMPFNKYLWSTYYNTVANMY*AQIFFGKTVKS*D IYLVKQTSMFPVLLSFDSSVRYCCALLFLQALH QLLRGPLGLVMQILNHPKTLTYRRHNSFPSDHC HNQCSTVSHH*GLMLTDIIFFIVINMWLY*LQAL PSNWHDI*AQKLRQKTKAKQIHGAEINLMPSPR QLISVYLNLGQIRVYTDAYRKFQEEARCIQFER YLWATK*GQD*TSGIHKAGTIRKCTPTKGPTKQA EVMQKSVLFP*NHQSRPPFF*RLVHHH*QLRSK HSSTLRD*NQTCISKLNGSISVIFLLFEGSWQK FHVYGIFTGQILLQEISKVWEWGGKKAQSVRIIL SH*TGAELCQDLGIFSEQILDIISIHILKRIPL SILFF*KYSV*KSLALNSFPAFHINVCRVSPSS KTLVGGGGCHRESCRRQEDSRIPQSY

Frame 1

PRLQRLCRRPSWVAISGGSLSKTQQSRQGRPRH RRRGAGRVGRPQQ*GARAGK*TRTDSCRFP*PP TDARAGNPDGT*LLTNNLLRGAPETPVFGASASV SIQVTFK*NLPKILGHTQKRLQSTRSWKRMMLS LNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRG HVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFK RAGCIVCNTLINEKWGREEITYDTPFKREKSFE IVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDT LGIYGKVNIHSIGFSFSSDLQSTQASSLELTEIS RENVPKSGTPQLRLPFAARLNTPMGPGRTVVVK GEVNANAKSFNVDLLAGKSKDIALHLNPRLNIK AFVRNSFLQESWGEEERNITSFPFSPGMYFEMII YCDVREFKVAVNGVHSLEYKHRFKELSSIDTLE INGDIHLLEVRSW*PTYTAATKTKIQNGFCDTG LAETHLTVILLFILLK*ACAPLGPAGCSQSLP*S MVVSSTEWGNWGQQHL*PVKATLPSLLLWLTLQ ECHSTSIYGVPTIIQ*LTCIEHRFFLVKL*RAR IYTW*NKPVCSLFS*ASTLLCATAAHCFFYRHYI NS*GVLWD*LCRY*ITRRH*LTEDTTPSPVITV ITSALPYPITED*C*LTSFSLS**TCGSISCKL YQVIGMTSEHRN*GKKPKQNKYMVLKLT*CQAQG S*FLCI*T*GKSESTQTPTESFRKRQDAFNLKD IYGQQSKVRIRLQAFIRQALSESVRQLRDPQSR QR*CRNLFCSHEITNQGLRSSKD*SIIISN*DQS TLPLYVIKIKPVSAS*MVPFL*FFYYLRGVGRS SMYMGSLQVRSCYRKFQRFGSGEGKKLSQ*GSF YHIRLGQNSARI*EYFQNRF*ILFLSIY*KEYHC QSYFFKSTQCRNR*PLILFQLFILMYAESHQAQ RHWLGVEGATGKAVEGKKTRESPRV

Frame 2

QGSRGCAGGRAGWRSAAGPCPKPSRAARDAPDT EGGARGGWGDHSSEAREPGSERGLTPVASRSRP RTPEPGTLTALSC*QTTCSVERLKHQSLGPVPQ FQSR*PLNETCLKS*VIHRRDSNRQEAGKE*CCP *TTYRISSITR*SRLLAPFLISWILEL*L*YVG MFLVTQTDSRWICRMAAA*NLEPMWPFISILVS KGPAALFAIL**MKNGDGKRSPMTRLSKEKSLLR S*LWC*RTNSRWL*MENILCSMATGSAQRK*TL WAFMAK*IFTQLVLASARTYKVPKHLVWN*QR* VEKMFQSLARPSLGCHSLQG*TPPWALDELSSLK EK*MQMPKALMLTY*QENQRILLYT*THA*ILK HL*EILFFRSPGEKKREILPLSHLVLGCTLR** FIVMLENSRLQ*MAYTAWSTNTDLKSSAVLTRWK LMETSTYWK*GAGSLPTQLLQKPKYRMASVILA LLKRISLSFYCLYC*NELVHH*VLLGVLSPCHE VWWCLALNGETGGSNTYSQLKPLCPLSYFG*LFK NAIQQVFMEYLL*YSS*HVLSTDFFW*NCEELG YILGETNQYVPCSLELRLFCALLLRTAFSTGIT STPKGSSGISYADIKSPEDTNLQKTQLLPQ*SLS *PVLYRIPSLRTDVD*HHFLYRNKHVALLAASF TK*LA*HLSTEIKAKNQSKTNTWC*N*LDAKPK AADFCVFELRANQSLHRRLQKVSGRGKMHSI*KI FMGNKVRSGLDFRHS*GRHYQKVYAN*GTHKAG RGNAEICFVPMKSPIKASVLLKISPSSLATEIK ALFHFT*LKSNLYQQVKWFHFCDFSII*GELAEV PCIWDLYRSDLVTGNFKGLGVGREKSSVSEDHF ITLDWGRTLPGFRNIFRTDFRYYFYPYIEKNTI VNLIFLKVLSVEIASP*FFSSFSY*CMQSLTKLK DTGWGWRVPQGKL*KARRLENPPEL

Sequence NM_201543

TGGACTTGGATCCGAGGCAGACGAGGAAGCTGAGAAAACCCTGGCGTTGACCCCGTGGACCTGGGCGCCCCGGGAAGGCCAGCGCTTGGTCCAGGCAGGC GGGGCCTGTGCGGTGACCACCCTGGTCCTGAAAAGTCCCAGCCCCGAGCGCCCTCCCTCCTAGACCTGGAGGCCTGGAACAGCCAGCCGCCCACGGACGC CAGAGCCGGGAACCCTGACGGCACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAACACCAGTCTTTGGGGCCAGTGCCTCAGTTTCAATC CAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACA ACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCC TAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAAAAGGGCC GGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGA TTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCAT TTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAA AATGTTCCAAAGTCTGGCACGCCCCAGCTTAGGCTGCCATTCGCTGCAAGGTTGAACACCCCCATGGGCCCTGGACGAACTGTCGTCGTTAAAGGAGAAG TGAATGCAAATGCCAAAAGCTTTAATGTTGACCTACTAGCAGGAAAATCAAAGGATATTGCTCTACACTTGAACCCACGCCTGAATATTAAAGCATTTGT AAGAAATTCTTTTCTTCAGGAGTCCTGGGGAGAAGAAGAGAGAAATATTACCTCTTTCCCATTTAGTCCTGGGATGTACTTTGAGATGATAATTTATTGT GATGTTAGAGAATTCAAGGTTGCAGTAAATGGCGTACACAGCCTGGAGTACAAACACAGATTTAAAGAGCTCAGCAGTATTGACACGCTGGAAATTAATG GAGACATCCACTTACTGGAAGTAAGGAGCTGGTAGCCTACCTACACAGCTGCTACAAAAACCAAAATACAGAATGGCTTCTGTGATACTGGCCTTGCTGA AACGCATCTCACTGTCATTCTATTGTTTATATTGTTAAAATGAGCTTGTGCACCATTAGGTCCTGCTGGGTGTTCTCAGTCCTTGCCATGAAGTATGGTG GTGTCTAGCACTGAATGGGGAAACTGGGGGCAGCAACACTTATAGCCAGTTAAAGCCACTCTGCCCTCTCTCCTACTTTGGCTGACTCTTCAAGAATGCC ATTCAACAAGTATTTATGGAGTACCTACTATAATACAGTAGCTAACATGTATTGAGCACAGATTTTTTTTGGTAAAACTGTGAAGAGCTAGGATATATAC TTGGTGAAACAAACCAGTATGTTCCCTGTTCTCTTGAGCTTCGACTCTTCTGTGCGCTACTGCTGCGCACTGCTTTTTCTACAGGCATTACATCAACTCC TAAGGGGTCCTCTGGGATTAGTTATGCAGATATTAAATCACCCGAAGACACTAACTTACAGAAGACACAACTCCTTCCCCAGTGATCACTGTCATAACCA GTGCTCTACCGTATCCCATCACTGAGGACTGATGTTGACTGACATCATTTTCTTTATCGTAATAAACATGTGGCTCTATTAGCTGCAAGCTTTACCAAGT AATTGGCATGACATCTGAGCACAGAAATTAAGGCAAAAAACCAAAGCAAAACAAATACATGGTGCTGAAATTAACTTGATGCCAAGCCCAAGGCAGCTGA TTTCTGTGTATTTGAACTTAGGGCAAATCAGAGTCTACACAGACGCCTACAGAAAGTTTCAGGAAGAGGCAAGATGCATTCAATTTGAAAGATATTTATG GGCAACAAAGTAAGGTCAGGATTAGACTTCAGGCATTCATAAGGCAGGCACTATCAGAAAGTGTACGCCAACTAAGGGACCCACAAAGCAGGCAGAGGTA ATGCAGAAATCTGTTTTGTTCCCATGAAATCACCAATCAAGGCCTCCGTTCTTCTAAAGATTAGTCCATCATCATTAGCAACTGAGATCAAAGCACTCTT CCACTTTACGTGATTAAAATCAAACCTGTATCAGCAAGTTAAATGGTTCCATTTCTGTGATTTTTCTATTATTTGAGGGGAGTTGGCAGAAGTTCCATGT ATATGGGATCTTTACAGGTCAGATCTTGTTACAGGAAATTTCAAAGGTTTGGGAGTGGGGAGGGAAAAAAGCTCAGTCAGTGAGGATCATTTTATCACAT TAGACTGGGGCAGAACTCTGCCAGGATTTAGGAATATTTTCAGAACAGATTTTAGATATTATTTCTATCCATATATTGAAAAGAATACCATTGTCAATCT TATTTTTTTAAAAGTACTCAGTGTAGAAATCGCTAGCCCTTAATTCTTTTCCAGCTTTTCATATTAATGTATGCAGAGTCTCACCAAGCTCAAAGACACT GGTTGGGGGTGGAGGGTGCCACAGGGAAAGCTGTAGAAGGCAAGAAGACTCGAGAATCCCCCAGAGTTAT

refseq_LGALS8.F2 (forward primer)
refseq_LGALS8.R2 (reverse primer)
Single exon skipping

Frame 0

WTWIRGRRGS*ENPGVDPVDLGAPGRPALGPGR RGLCGDHPGPEKSQPRAPSLLDLEAWNSQPPTDA RAGNPDGT*LLTNNLLRGAPETPVFGASASVSI QVTFK*NLPKILGHTQKRLQSTRSWKRMMLSLN NLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVP SDADRFQVDLQNGSSMKPRADVAFHFNPRFKRA GCIVCNTLINEKWGREEITYDTPFKREKSFEIV IMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGI YGKVNIHSIGFSFSSDLQSTQASSLELTEISRE NVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGE VNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFV RNSFLQESWGEEERNITSFPFSPGMYFEMIIYC DVREFKVAVNGVHSLEYKHRFKELSSIDTLEIN GDIHLLEVRSW*PTYTAATKTKIQNGFCDTGLAE THLTVILLFILLK*ACAPLGPAGCSQSLP*SMV VSSTEWGNWGQQHL*PVKATLPSLLLWLTLQEC HSTSIYGVPTIIQ*LTCIEHRFFLVKL*RARIYT W*NKPVCSLFS*ASTLLCATAAHCFFYRHYINS *GVLWD*LCRY*ITRRH*LTEDTTPSPVITVIT SALPYPITED*C*LTSFSLS**TCGSISCKLYQV IGMTSEHRN*GKKPKQNKYMVLKLT*CQAQGS* FLCI*T*GKSESTQTPTESFRKRQDAFNLKDIY GQQSKVRIRLQAFIRQALSESVRQLRDPQSRQR* CRNLFCSHEITNQGLRSSKD*SIIISN*DQSTL PLYVIKIKPVSAS*MVPFL*FFYYLRGVGRSSM YMGSLQVRSCYRKFQRFGSGEGKKLSQ*GSFYHI RLGQNSARI*EYFQNRF*ILFLSIY*KEYHCQS YFFKSTQCRNR*PLILFQLFILMYAESHQAQRH WLGVEGATGKAVEGKKTRESPRV

Frame 1

GLGSEADEEAEKTLALTPWTWAPREGQRLVQAG GACAVTTLVLKSPSPERPPS*TWRPGTASRPRT PEPGTLTALSC*QTTCSVERLKHQSLGPVPQFQS R*PLNETCLKS*VIHRRDSNRQEAGKE*CCP*T TYRISSITR*SRLLAPFLISWILEL*L*YVGMF LVTQTDSRWICRMAAA*NLEPMWPFISILVSKGP AALFAIL**MKNGDGKRSPMTRLSKEKSLLRS* LWC*RTNSRWL*MENILCSMATGSAQRK*TLWA FMAK*IFTQLVLASARTYKVPKHLVWN*QR*VEK MFQSLARPSLGCHSLQG*TPPWALDELSSLKEK *MQMPKALMLTY*QENQRILLYT*THA*ILKHL *EILFFRSPGEKKREILPLSHLVLGCTLR**FIV MLENSRLQ*MAYTAWSTNTDLKSSAVLTRWKLM ETSTYWK*GAGSLPTQLLQKPKYRMASVILALL KRISLSFYCLYC*NELVHH*VLLGVLSPCHEVWW CLALNGETGGSNTYSQLKPLCPLSYFG*LFKNA IQQVFMEYLL*YSS*HVLSTDFFW*NCEELGYI LGETNQYVPCSLELRLFCALLLRTAFSTGITSTP KGSSGISYADIKSPEDTNLQKTQLLPQ*SLS*P VLYRIPSLRTDVD*HHFLYRNKHVALLAASFTK *LA*HLSTEIKAKNQSKTNTWC*N*LDAKPKAAD FCVFELRANQSLHRRLQKVSGRGKMHSI*KIFM GNKVRSGLDFRHS*GRHYQKVYAN*GTHKAGRG NAEICFVPMKSPIKASVLLKISPSSLATEIKALF HFT*LKSNLYQQVKWFHFCDFSII*GELAEVPC IWDLYRSDLVTGNFKGLGVGREKSSVSEDHFIT LDWGRTLPGFRNIFRTDFRYYFYPYIEKNTIVNL IFLKVLSVEIASP*FFSSFSY*CMQSLTKLKDT GWGWRVPQGKL*KARRLENPPEL

Frame 2

DLDPRQTRKLRKPWR*PRGPGRPGKASAWSRQA GPVR*PPWS*KVPAPSALPPRPGGLEQPAAHGR QSREP*RHLAADKQPAPWSA*NTSLWGQCLSFN PGNL*MKLA*NLRSYTEETPIDKKLEKNDVVLKQ PTEYHL*PGNPVCWHHS*SAGSWNFDCDTWACS **RRQIPGGSAEWQQHETSSRCGLSFQSSFQKG RLHCLQYFDK*KMGTGRDHL*HAFQKRKVF*DRD YGAEGQIPGGCKWKTYSALWPQDRPRENRHSGH LWQSEYSLNWF*LQLGLTKYPSI*SGTDRDK*R KCSKVWHAPA*AAIRCKVEHPHGPWTNCRR*RRS ECKCQKL*C*PTSRKIKGYCSTLEPTPEY*SIC KKFFSSGVLGRRREKYYLFPI*SWDVL*DDNLL *C*RIQGCSKWRTQPGVQTQI*RAQQY*HAGN*W RHPLTGSKELVAYLHSCYKNQNTEWLL*YWPC* NASHCHSIVYIVKMSLCTIRSCWVFSVLAMKYG GV*H*MGKLGAATLIAS*SHSALSPTLADSSRMP FNKYLWSTYYNTVANMY*AQIFFGKTVKS*DIY LVKQTSMFPVLLSFDSSVRYCCALLFLQALHQL LRGPLGLVMQILNHPKTLTYRRHNSFPSDHCHNQ CSTVSHH*GLMLTDIIFFIVINMWLY*LQALPS NWHDI*AQKLRQKTKAKQIHGAEINLMPSPRQL ISVYLNLGQIRVYTDAYRKFQEEARCIQFERYLW ATK*GQD*TSGIHKAGTIRKCTPTKGPTKQAEV MQKSVLFP*NHQSRPPFF*RLVHHH*QLRSKHS STLRD*NQTCISKLNGSISVIFLLFEGSWQKFHV YGIFTGQILLQEISKVWEWGGKKAQSVRIILSH *TGAELCQDLGIFSEQILDIISIHILKRIPLSI LFF*KYSV*KSLALNSFPAFHINVCRVSPSSKTL VGGGGCHRESCRRQEDSRIPQSY

Sequence NM_201545

GATCCTGTAGAACTTCGGAGATTGGGGAAGATAATCGGAAGAGGTAGAAGACACCGTCCATGACACTTCCTGGGGAAGCAGATGTATGTATAAGGATGGC CAGTGCCTCAGTTTCAATCCAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGA ATGATGTTGTCCTTAAACAACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTG TGATACGTGGGCATGTTCCTAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAA TCCTCGTTTCAAAAGGGCCGGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAA AAGTCTTTTGAGATCGTGATTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGA AAATAGACACTCTGGGCATTTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACT GACAGAGATAAGTAGAGAAAATGTTCCAAAGTCTGGCACGCCCCAGCTTCCTAGTAATAGAGGAGGAGACATTTCTAAAATCGCACCCAGAACTGTCTAC ACCAAGAGCAAAGATTCGACTGTCAATCACACTTTGACTTGCACCAAAATACCACCTATGAACTATGTGTCAAAGAGGCTGCCATTCGCTGCAAGGTTGA ACACCCCCATGGGCCCTGGACGAACTGTCGTCGTTAAAGGAGAAGTGAATGCAAATGCCAAAAGCTTTAATGTTGACCTACTAGCAGGAAAATCAAAGGA TATTGCTCTACACTTGAACCCACGCCTGAATATTAAAGCATTTGTAAGAAATTCTTTTCTTCAGGAGTCCTGGGGAGAAGAAGAGAGAAATATTACCTCT TTCCCATTTAGTCCTGGGATGTACTTTGAGATGATAATTTATTGTGATGTTAGAGAATTCAAGGTTGCAGTAAATGGCGTACACAGCCTGGAGTACAAAC ACAGATTTAAAGAGCTCAGCAGTATTGACACGCTGGAAATTAATGGAGACATCCACTTACTGGAAGTAAGGAGCTGGTAGCCTACCTACACAGCTGCTAC AAAAACCAAAATACAGAATGGCTTCTGTGATACTGGCCTTGCTGAAACGCATCTCACTGTCATTCTATTGTTTATATTGTTAAAATGAGCTTGTGCACCA TTAGGTCCTGCTGGGTGTTCTCAGTCCTTGCCATGAAGTATGGTGGTGTCTAGCACTGAATGGGGAAACTGGGGGCAGCAACACTTATAGCCAGTTAAAG CCACTCTGCCCTCTCTCCTACTTTGGCTGACTCTTCAAGAATGCCATTCAACAAGTATTTATGGAGTACCTACTATAATACAGTAGCTAACATGTATTGA GCACAGATTTTTTTTGGTAAAACTGTGAAGAGCTAGGATATATACTTGGTGAAACAAACCAGTATGTTCCCTGTTCTCTTGAGCTTCGACTCTTCTGTGC GCTACTGCTGCGCACTGCTTTTTCTACAGGCATTACATCAACTCCTAAGGGGTCCTCTGGGATTAGTTATGCAGATATTAAATCACCCGAAGACACTAAC TTACAGAAGACACAACTCCTTCCCCAGTGATCACTGTCATAACCAGTGCTCTACCGTATCCCATCACTGAGGACTGATGTTGACTGACATCATTTTCTTT ATCGTAATAAACATGTGGCTCTATTAGCTGCAAGCTTTACCAAGTAATTGGCATGACATCTGAGCACAGAAATTAAGGCAAAAAACCAAAGCAAAACAAA TACATGGTGCTGAAATTAACTTGATGCCAAGCCCAAGGCAGCTGATTTCTGTGTATTTGAACTTAGGGCAAATCAGAGTCTACACAGACGCCTACAGAAA GTTTCAGGAAGAGGCAAGATGCATTCAATTTGAAAGATATTTATGGGCAACAAAGTAAGGTCAGGATTAGACTTCAGGCATTCATAAGGCAGGCACTATC AGAAAGTGTACGCCAACTAAGGGACCCACAAAGCAGGCAGAGGTAATGCAGAAATCTGTTTTGTTCCCATGAAATCACCAATCAAGGCCTCCGTTCTTCT AAAGATTAGTCCATCATCATTAGCAACTGAGATCAAAGCACTCTTCCACTTTACGTGATTAAAATCAAACCTGTATCAGCAAGTTAAATGGTTCCATTTC TGTGATTTTTCTATTATTTGAGGGGAGTTGGCAGAAGTTCCATGTATATGGGATCTTTACAGGTCAGATCTTGTTACAGGAAATTTCAAAGGTTTGGGAG TGGGGAGGGAAAAAAGCTCAGTCAGTGAGGATCATTTTATCACATTAGACTGGGGCAGAACTCTGCCAGGATTTAGGAATATTTTCAGAACAGATTTTAG ATATTATTTCTATCCATATATTGAAAAGAATACCATTGTCAATCTTATTTTTTTAAAAGTACTCAGTGTAGAAATCGCTAGCCCTTAATTCTTTTCCAGC TTTTCATATTAATGTATGCAGAGTCTCACCAAGCTCAAAGACACTGGTTGGGGGTGGAGGGTGCCACAGGGAAAGCTGTAGAAGGCAAGAAGACTCGAGA ATCCCCCAGAGTTAT

refseq_LGALS8.F2 (forward primer)
refseq_LGALS8.R2 (reverse primer)
Single exon skipping

Frame 0

DPVELRRLGKIIGRGRRHRP*HFLGKQMYV*GW PVPQFQSR*PLNETCLKS*VIHRRDSNRQEAGKE *CCP*TTYRISSITR*SRLLAPFLISWILEL*L *YVGMFLVTQTDSRWICRMAAA*NLEPMWPFIS ILVSKGPAALFAIL**MKNGDGKRSPMTRLSKEK SLLRS*LWC*RTNSRWL*MENILCSMATGSAQR K*TLWAFMAK*IFTQLVLASARTYKVPKHLVWN *QR*VEKMFQSLARPSFLVIEEETFLKSHPELST PRAKIRLSITL*LAPKYHL*TMCQRGCHSLQG* TPPWALDELSSLKEK*MQMPKALMLTY*QENQR ILLYT*THA*ILKHL*EILFFRSPGEKKREILPL SHLVLGCTLR**FIVMLENSRLQ*MAYTAWSTN TDLKSSAVLTRWKLMETSTYWK*GAGSLPTQLL QKPKYRMASVILALLKRISLSFYCLYC*NELVHH *VLLGVLSPCHEVWWCLALNGETGGSNTYSQLK PLCPLSYFG*LFKNAIQQVFMEYLL*YSS*HVL STDFFW*NCEELGYILGETNQYVPCSLELRLFCA LLLRTAFSTGITSTPKGSSGISYADIKSPEDTN LQKTQLLPQ*SLS*PVLYRIPSLRTDVD*HHFL YRNKHVALLAASFTK*LA*HLSTEIKAKNQSKTN TWC*N*LDAKPKAADFCVFELRANQSLHRRLQK VSGRGKMHSI*KIFMGNKVRSGLDFRHS*GRHY QKVYAN*GTHKAGRGNAEICFVPMKSPIKASVLL KISPSSLATEIKALFHFT*LKSNLYQQVKWFHF CDFSII*GELAEVPCIWDLYRSDLVTGNFKGLG VGREKSSVSEDHFITLDWGRTLPGFRNIFRTDFR YYFYPYIEKNTIVNLIFLKVLSVEIASP*FFSS FSY*CMQSLTKLKDTGWGWRVPQGKL*KARRLE NPPEL

Frame 1

IL*NFGDWGR*SEEVEDTVHDTSWGSRCMYKDG QCLSFNPGNL*MKLA*NLRSYTEETPIDKKLEK NDVVLKQPTEYHL*PGNPVCWHHS*SAGSWNFDC DTWACS**RRQIPGGSAEWQQHETSSRCGLSFQ SSFQKGRLHCLQYFDK*KMGTGRDHL*HAFQKR KVF*DRDYGAEGQIPGGCKWKTYSALWPQDRPRE NRHSGHLWQSEYSLNWF*LQLGLTKYPSI*SGT DRDK*RKCSKVWHAPAS***RRRHF*NRTQNCL HQEQRFDCQSHFDLHQNTTYELCVKEAAIRCKVE HPHGPWTNCRR*RRSECKCQKL*C*PTSRKIKG YCSTLEPTPEY*SICKKFFSSGVLGRRREKYYL FPI*SWDVL*DDNLL*C*RIQGCSKWRTQPGVQT QI*RAQQY*HAGN*WRHPLTGSKELVAYLHSCY KNQNTEWLL*YWPC*NASHCHSIVYIVKMSLCT IRSCWVFSVLAMKYGGV*H*MGKLGAATLIAS*S HSALSPTLADSSRMPFNKYLWSTYYNTVANMY* AQIFFGKTVKS*DIYLVKQTSMFPVLLSFDSSV RYCCALLFLQALHQLLRGPLGLVMQILNHPKTLT YRRHNSFPSDHCHNQCSTVSHH*GLMLTDIIFF IVINMWLY*LQALPSNWHDI*AQKLRQKTKAKQ IHGAEINLMPSPRQLISVYLNLGQIRVYTDAYRK FQEEARCIQFERYLWATK*GQD*TSGIHKAGTI RKCTPTKGPTKQAEVMQKSVLFP*NHQSRPPFF *RLVHHH*QLRSKHSSTLRD*NQTCISKLNGSIS VIFLLFEGSWQKFHVYGIFTGQILLQEISKVWE WGGKKAQSVRIILSH*TGAELCQDLGIFSEQIL DIISIHILKRIPLSILFF*KYSV*KSLALNSFPA FHINVCRVSPSSKTLVGGGGCHRESCRRQEDSR IPQSY

Frame 2

SCRTSEIGEDNRKR*KTPSMTLPGEADVCIRMA SASVSIQVTFK*NLPKILGHTQKRLQSTRSWKR MMLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLI VIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFN PRFKRAGCIVCNTLINEKWGREEITYDTPFKRE KSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPE KIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLEL TEISRENVPKSGTPQLPSNRGGDISKIAPRTVY TKSKDSTVNHTLTCTKIPPMNYVSKRLPFAARL NTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKD IALHLNPRLNIKAFVRNSFLQESWGEEERNITS FPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYK HRFKELSSIDTLEINGDIHLLEVRSW*PTYTAAT KTKIQNGFCDTGLAETHLTVILLFILLK*ACAP LGPAGCSQSLP*SMVVSSTEWGNWGQQHL*PVK ATLPSLLLWLTLQECHSTSIYGVPTIIQ*LTCIE HRFFLVKL*RARIYTW*NKPVCSLFS*ASTLLC ATAAHCFFYRHYINS*GVLWD*LCRY*ITRRH* LTEDTTPSPVITVITSALPYPITED*C*LTSFSL S**TCGSISCKLYQVIGMTSEHRN*GKKPKQNK YMVLKLT*CQAQGS*FLCI*T*GKSESTQTPTE SFRKRQDAFNLKDIYGQQSKVRIRLQAFIRQALS ESVRQLRDPQSRQR*CRNLFCSHEITNQGLRSS KD*SIIISN*DQSTLPLYVIKIKPVSAS*MVPF L*FFYYLRGVGRSSMYMGSLQVRSCYRKFQRFGS GEGKKLSQ*GSFYHIRLGQNSARI*EYFQNRF* ILFLSIY*KEYHCQSYFFKSTQCRNR*PLILFQ LFILMYAESHQAQRHWLGVEGATGKAVEGKKTRE SPRV

Sequence NM_006499

TGGACTTGGATCCGAGGCAGACGAGGAAGCTGAGAAAACCCTGGCGTTGACCCCGTGGACCTGGGCGCCCCGGGAAGGCCAGCGCTTGGTCCAGGCAGGC GGGGCCTGTGCGGTGACCACCCTGGTCCTGAAAAGTCCCAGCCCCGAGCGCCCTCCCTCCTAGACCTGGAGGCCTGGAACAGCCAGCCGCCCACGGACGC CAGAGCCGGGAACCCTGACGGCACTTAGCTGCTGACAAACAACCTGCTCCGTGGAGCGCCTGAAACACCAGTCTTTGGGGCCAGTGCCTCAGTTTCAATC CAGGTAACCTTTAAATGAAACTTGCCTAAAATCTTAGGTCATACACAGAAGAGACTCCAATCGACAAGAAGCTGGAAAAGAATGATGTTGTCCTTAAACA ACCTACAGAATATCATCTATAACCCGGTAATCCCGTTTGTTGGCACCATTCCTGATCAGCTGGATCCTGGAACTTTGATTGTGATACGTGGGCATGTTCC TAGTGACGCAGACAGATTCCAGGTGGATCTGCAGAATGGCAGCAGCATGAAACCTCGAGCCGATGTGGCCTTTCATTTCAATCCTCGTTTCAAAAGGGCC GGCTGCATTGTTTGCAATACTTTGATAAATGAAAAATGGGGACGGGAAGAGATCACCTATGACACGCCTTTCAAAAGAGAAAAGTCTTTTGAGATCGTGA TTATGGTGCTGAAGGACAAATTCCAGGTGGCTGTAAATGGAAAACATACTCTGCTCTATGGCCACAGGATCGGCCCAGAGAAAATAGACACTCTGGGCAT TTATGGCAAAGTGAATATTCACTCAATTGGTTTTAGCTTCAGCTCGGACTTACAAAGTACCCAAGCATCTAGTCTGGAACTGACAGAGATAAGTAGAGAA AATGTTCCAAAGTCTGGCACGCCCCAGCTTCCTAGTAATAGAGGAGGAGACATTTCTAAAATCGCACCCAGAACTGTCTACACCAAGAGCAAAGATTCGA CTGTCAATCACACTTTGACTTGCACCAAAATACCACCTATGAACTATGTGTCAAAGAGGCTGCCATTCGCTGCAAGGTTGAACACCCCCATGGGCCCTGG ACGAACTGTCGTCGTTAAAGGAGAAGTGAATGCAAATGCCAAAAGCTTTAATGTTGACCTACTAGCAGGAAAATCAAAGGATATTGCTCTACACTTGAAC CCACGCCTGAATATTAAAGCATTTGTAAGAAATTCTTTTCTTCAGGAGTCCTGGGGAGAAGAAGAGAGAAATATTACCTCTTTCCCATTTAGTCCTGGGA TGTACTTTGAGATGATAATTTATTGTGATGTTAGAGAATTCAAGGTTGCAGTAAATGGCGTACACAGCCTGGAGTACAAACACAGATTTAAAGAGCTCAG CAGTATTGACACGCTGGAAATTAATGGAGACATCCACTTACTGGAAGTAAGGAGCTGGTAGCCTACCTACACAGCTGCTACAAAAACCAAAATACAGAAT GGCTTCTGTGATACTGGCCTTGCTGAAACGCATCTCACTGTCATTCTATTGTTTATATTGTTAAAATGAGCTTGTGCACCATTAGGTCCTGCTGGGTGTT CTCAGTCCTTGCCATGAAGTATGGTGGTGTCTAGCACTGAATGGGGAAACTGGGGGCAGCAACACTTATAGCCAGTTAAAGCCACTCTGCCCTCTCTCCT ACTTTGGCTGACTCTTCAAGAATGCCATTCAACAAGTATTTATGGAGTACCTACTATAATACAGTAGCTAACATGTATTGAGCACAGATTTTTTTTGGTA AAACTGTGAAGAGCTAGGATATATACTTGGTGAAACAAACCAGTATGTTCCCTGTTCTCTTGAGCTTCGACTCTTCTGTGCGCTACTGCTGCGCACTGCT TTTTCTACAGGCATTACATCAACTCCTAAGGGGTCCTCTGGGATTAGTTATGCAGATATTAAATCACCCGAAGACACTAACTTACAGAAGACACAACTCC TTCCCCAGTGATCACTGTCATAACCAGTGCTCTACCGTATCCCATCACTGAGGACTGATGTTGACTGACATCATTTTCTTTATCGTAATAAACATGTGGC TCTATTAGCTGCAAGCTTTACCAAGTAATTGGCATGACATCTGAGCACAGAAATTAAGGCAAAAAACCAAAGCAAAACAAATACATGGTGCTGAAATTAA CTTGATGCCAAGCCCAAGGCAGCTGATTTCTGTGTATTTGAACTTAGGGCAAATCAGAGTCTACACAGACGCCTACAGAAAGTTTCAGGAAGAGGCAAGA TGCATTCAATTTGAAAGATATTTATGGGCAACAAAGTAAGGTCAGGATTAGACTTCAGGCATTCATAAGGCAGGCACTATCAGAAAGTGTACGCCAACTA AGGGACCCACAAAGCAGGCAGAGGTAATGCAGAAATCTGTTTTGTTCCCATGAAATCACCAATCAAGGCCTCCGTTCTTCTAAAGATTAGTCCATCATCA TTAGCAACTGAGATCAAAGCACTCTTCCACTTTACGTGATTAAAATCAAACCTGTATCAGCAAGTTAAATGGTTCCATTTCTGTGATTTTTCTATTATTT GAGGGGAGTTGGCAGAAGTTCCATGTATATGGGATCTTTACAGGTCAGATCTTGTTACAGGAAATTTCAAAGGTTTGGGAGTGGGGAGGGAAAAAAGCTC AGTCAGTGAGGATCATTTTATCACATTAGACTGGGGCAGAACTCTGCCAGGATTTAGGAATATTTTCAGAACAGATTTTAGATATTATTTCTATCCATAT ATTGAAAAGAATACCATTGTCAATCTTATTTTTTTAAAAGTACTCAGTGTAGAAATCGCTAGCCCTTAATTCTTTTCCAGCTTTTCATATTAATGTATGC AGAGTCTCACCAAGCTCAAAGACACTGGTTGGGGGTGGAGGGTGCCACAGGGAAAGCTGTAGAAGGCAAGAAGACTCGAGAATCCCCCAGAGTTAT

refseq_LGALS8.F2 (forward primer)
refseq_LGALS8.R2 (reverse primer)
Single exon skipping

Frame 0

WTWIRGRRGS*ENPGVDPVDLGAPGRPALGPGR RGLCGDHPGPEKSQPRAPSLLDLEAWNSQPPTDA RAGNPDGT*LLTNNLLRGAPETPVFGASASVSI QVTFK*NLPKILGHTQKRLQSTRSWKRMMLSLN NLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVP SDADRFQVDLQNGSSMKPRADVAFHFNPRFKRA GCIVCNTLINEKWGREEITYDTPFKREKSFEIV IMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGI YGKVNIHSIGFSFSSDLQSTQASSLELTEISRE NVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDS TVNHTLTCTKIPPMNYVSKRLPFAARLNTPMGPG RTVVVKGEVNANAKSFNVDLLAGKSKDIALHLN PRLNIKAFVRNSFLQESWGEEERNITSFPFSPG MYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELS SIDTLEINGDIHLLEVRSW*PTYTAATKTKIQN GFCDTGLAETHLTVILLFILLK*ACAPLGPAGC SQSLP*SMVVSSTEWGNWGQQHL*PVKATLPSLL LWLTLQECHSTSIYGVPTIIQ*LTCIEHRFFLV KL*RARIYTW*NKPVCSLFS*ASTLLCATAAHC FFYRHYINS*GVLWD*LCRY*ITRRH*LTEDTTP SPVITVITSALPYPITED*C*LTSFSLS**TCG SISCKLYQVIGMTSEHRN*GKKPKQNKYMVLKL T*CQAQGS*FLCI*T*GKSESTQTPTESFRKRQD AFNLKDIYGQQSKVRIRLQAFIRQALSESVRQL RDPQSRQR*CRNLFCSHEITNQGLRSSKD*SII ISN*DQSTLPLYVIKIKPVSAS*MVPFL*FFYYL RGVGRSSMYMGSLQVRSCYRKFQRFGSGEGKKL SQ*GSFYHIRLGQNSARI*EYFQNRF*ILFLSI Y*KEYHCQSYFFKSTQCRNR*PLILFQLFILMYA ESHQAQRHWLGVEGATGKAVEGKKTRESPRV

Frame 1

GLGSEADEEAEKTLALTPWTWAPREGQRLVQAG GACAVTTLVLKSPSPERPPS*TWRPGTASRPRT PEPGTLTALSC*QTTCSVERLKHQSLGPVPQFQS R*PLNETCLKS*VIHRRDSNRQEAGKE*CCP*T TYRISSITR*SRLLAPFLISWILEL*L*YVGMF LVTQTDSRWICRMAAA*NLEPMWPFISILVSKGP AALFAIL**MKNGDGKRSPMTRLSKEKSLLRS* LWC*RTNSRWL*MENILCSMATGSAQRK*TLWA FMAK*IFTQLVLASARTYKVPKHLVWN*QR*VEK MFQSLARPSFLVIEEETFLKSHPELSTPRAKIR LSITL*LAPKYHL*TMCQRGCHSLQG*TPPWAL DELSSLKEK*MQMPKALMLTY*QENQRILLYT*T HA*ILKHL*EILFFRSPGEKKREILPLSHLVLG CTLR**FIVMLENSRLQ*MAYTAWSTNTDLKSS AVLTRWKLMETSTYWK*GAGSLPTQLLQKPKYRM ASVILALLKRISLSFYCLYC*NELVHH*VLLGV LSPCHEVWWCLALNGETGGSNTYSQLKPLCPLS YFG*LFKNAIQQVFMEYLL*YSS*HVLSTDFFW* NCEELGYILGETNQYVPCSLELRLFCALLLRTA FSTGITSTPKGSSGISYADIKSPEDTNLQKTQL LPQ*SLS*PVLYRIPSLRTDVD*HHFLYRNKHVA LLAASFTK*LA*HLSTEIKAKNQSKTNTWC*N* LDAKPKAADFCVFELRANQSLHRRLQKVSGRGK MHSI*KIFMGNKVRSGLDFRHS*GRHYQKVYAN* GTHKAGRGNAEICFVPMKSPIKASVLLKISPSS LATEIKALFHFT*LKSNLYQQVKWFHFCDFSII *GELAEVPCIWDLYRSDLVTGNFKGLGVGREKSS VSEDHFITLDWGRTLPGFRNIFRTDFRYYFYPY IEKNTIVNLIFLKVLSVEIASP*FFSSFSY*CM QSLTKLKDTGWGWRVPQGKL*KARRLENPPEL

Frame 2

DLDPRQTRKLRKPWR*PRGPGRPGKASAWSRQA GPVR*PPWS*KVPAPSALPPRPGGLEQPAAHGR QSREP*RHLAADKQPAPWSA*NTSLWGQCLSFN PGNL*MKLA*NLRSYTEETPIDKKLEKNDVVLKQ PTEYHL*PGNPVCWHHS*SAGSWNFDCDTWACS **RRQIPGGSAEWQQHETSSRCGLSFQSSFQKG RLHCLQYFDK*KMGTGRDHL*HAFQKRKVF*DRD YGAEGQIPGGCKWKTYSALWPQDRPRENRHSGH LWQSEYSLNWF*LQLGLTKYPSI*SGTDRDK*R KCSKVWHAPAS***RRRHF*NRTQNCLHQEQRFD CQSHFDLHQNTTYELCVKEAAIRCKVEHPHGPW TNCRR*RRSECKCQKL*C*PTSRKIKGYCSTLE PTPEY*SICKKFFSSGVLGRRREKYYLFPI*SWD VL*DDNLL*C*RIQGCSKWRTQPGVQTQI*RAQ QY*HAGN*WRHPLTGSKELVAYLHSCYKNQNTE WLL*YWPC*NASHCHSIVYIVKMSLCTIRSCWVF SVLAMKYGGV*H*MGKLGAATLIAS*SHSALSP TLADSSRMPFNKYLWSTYYNTVANMY*AQIFFG KTVKS*DIYLVKQTSMFPVLLSFDSSVRYCCALL FLQALHQLLRGPLGLVMQILNHPKTLTYRRHNS FPSDHCHNQCSTVSHH*GLMLTDIIFFIVINMW LY*LQALPSNWHDI*AQKLRQKTKAKQIHGAEIN LMPSPRQLISVYLNLGQIRVYTDAYRKFQEEAR CIQFERYLWATK*GQD*TSGIHKAGTIRKCTPT KGPTKQAEVMQKSVLFP*NHQSRPPFF*RLVHHH *QLRSKHSSTLRD*NQTCISKLNGSISVIFLLF EGSWQKFHVYGIFTGQILLQEISKVWEWGGKKA QSVRIILSH*TGAELCQDLGIFSEQILDIISIHI LKRIPLSILFF*KYSV*KSLALNSFPAFHINVC RVSPSSKTLVGGGGCHRESCRRQEDSRIPQSY