Back to Rnomics Platform
Open Session
×
1 warning:
- Access restricted to public data.
Please sign in at Rnomics Platform to access your data.
Sequence NM_170606
GAGGTGCGCGCGCCCGCGCCGATGTGTGTGAGTGCGTGTCCTGCTCGCTCCATGTTGCCGCCTCTCCCGGTACCTGCTGCTGCTCCCGGGGCTGCGGGAAATGCGAGAGGCTGAGCCGGGGAGGAGGAACCCGAGCAGCAGCGGCGGCGGCGGCGGCCGCGGCGGCGGGAGCCCCCCAGGAGGAGGACCGGGATCCATGT
GTCTTTCCTGGTGACTAGGATGTCGTCGGAGGAGGACAAGAGCGTGGAGCAGCCGCAGCCGCCGCCACCACCCCCCGAGGAGCCTGGAGCCCCGGCCCCG
AGCCCCGCAGCCGCAGACAAAAGACCTCGGGGCCGGCCTCGCAAAGATGGCGCTTCCCCTTTCCAGAGAGCCAGAAAGAAACCTCGAAGTAGGGGGAAAA
CTGCAGTGGAAGATGAGGACAGCATGGATGGGCTGGAGACAACAGAAACAGAAACGATTGTGGAAACAGAAATCAAAGAACAATCTGCAGAAGAGGATGC
TGAAGCAGAAGTGGATAACAGCAAACAGCTAATTCCAACTCTTCAGCGATCTGTGTCTGAGGAATCGGCAAACTCCCTGGTCTCTGTTGGTGTAGAAGCC
AAAATCAGTGAACAGCTCTGCGCTTTTTGTTACTGTGGGGAAAAAAGTTCCTTAGGACAAGGAGACTTAAAACAATTCAGAATAACGCCTGGATTTATCT
TGCCATGGAGAAACCAACCTTCTAACAAGAAGGACATTGATGACAACAGCAATGGAACCTATGAGAAAATGCAAAACTCAGCACCACGAAAACAAAGAGG
ACAGAGAAAAGAACGATCTCCTCAGCAGAATATAGTATCTTGTGTAAGTGTAAGCACCCAGACAGCTTCAGATGATCAAGCTGGTAAACTGTGGGATGAA
CTCAGTCTGGTTGGGCTTCCAGATGCCATTGATATCCAAGCCTTATTTGATTCTACAGGCACTTGTTGGGCTCATCACCGTTGTGTGGAGTGGTCACTAG
GAGTATGCCAGATGGAAGAACCATTGTTAGTGAACGTGGACAAAGCTGTTGTCTCAGGGAGCACAGAACGATGTGCATTTTGTAAGCACCTTGGAGCCAC
TATCAAATGCTGTGAAGAGAAATGTACCCAGATGTATCATTATCCTTGTGCTGCAGGAGCCGGCACCTTTCAGGATTTCAGTCACATCTTCCTGCTTTGT
CCAGAACACATTGACCAAGCTCCTGAAAGATCGAAGGAAGATGCAAACTGTGCAGTGTGCGACAGCCCGGGAGACCTCTTAGATCAGTTCTTTTGTACTA
CTTGTGGTCAGCACTATCATGGAATGTGCCTGGATATAGCGGTTACTCCATTAAAACGTGCAGGTTGGCAATGTCCTGAGTGCAAAGTGTGCCAGAACTG
CAAACAATCGGGAGAAGATAGCAAGATGCTAGTGTGTGATACGTGTGACAAAGGGTATCATACTTTTTGTCTTCAACCAGTTATGAAATCAGTACCAACC
AATGGCTGGAAATGCAAAAATTGCAGAATATGTATAGAGTGTGGCACACGGTCTAGTTCTCAGTGGCACCACAATTGCCTGATATGTGACAATTGTTACC
AACAGCAGGATAACTTATGTCCCTTCTGTGGGAAGTGTTATCATCCAGAATTGCAGAAAGACATGCTTCATTGTAATATGTGCAAAAGGTGGGTTCACCT
AGAGTGTGACAAACCAACAGATCATGAACTGGATACTCAGCTCAAAGAAGAGTATATCTGCATGTATTGTAAACACCTGGGAGCTGAGATGGATCGTTTA
CAGCCAGGTGAGGAAGTGGAGATAGCTGAGCTCACTACAGATTATAACAATGAAATGGAAGTTGAAGGCCCTGAAGATCAAATGGTATTCTCAGAGCAGG
CAGCTAATAAAGATGTCAACGGTCAGGAGTCCACTCCTGGAATTGTTCCAGATGCGGTTCAAGTCCACACTGAAGAGCAACAGAAGAGTCATCCCTCAGA
AAGTCTTGACACAGATAGTCTTCTTATTGCTGTATCATCCCAACATACAGTGAATACTGAATTGGAAAAACAGATTTCTAATGAAGTTGATAGTGAAGAC
CTGAAAATGTCTTCTGAAGTGAAGCATATTTGTGGCGAAGATCAAATTGAAGATAAAATGGAAGTGACAGAAAACATTGAAGTCGTTACACACCAGATCA
CTGTGCAGCAAGAACAACTGCAGTTGTTAGAGGAACCTGAAACAGTGGTATCCAGAGAAGAATCAAGGCCTCCAAAATTAGTCATGGAATCTGTCACTCT
TCCACTAGAAACCTTAGTGTCCCCACATGAGGAAAGTATTTCATTATGTCCTGAGGAACAGTTGGTTATAGAAAGGCTACAAGGAGAAAAGGAACAGAAA
GAAAATTCTGAACTTTCTACTGGATTGATGGACTCTGAAATGACTCCTACAATTGAGGGTTGTGTGAAAGATGTTTCATACCAAGGAGGCAAATCTATAA
AGTTATCATCTGAGACAGAGTCATCATTTTCATCATCAGCAGACATAAGCAAGGCAGATGTGTCTTCCTCCCCAACACCTTCTTCAGACTTGCCTTCGCA
TGACATGCTGCATAATTACCCTTCAGCTCTTAGTTCCTCTGCTGGAAACATCATGCCAACAACTTACATCTCAGTCACTCCAAAAATTGGCATGGGTAAA
CCAGCTATTACTAAGAGAAAATTTTCTCCTGGTAGACCTCGGTCCAAACAGGGGGCTTGGAGTACCCATAATACAGTGAGCCCACCTTCCTGGTCCCCAG
ACATTTCAGAAGGTCGGGAAATTTTTAAACCCAGGCAGCTTCCTGGCAGTGCCATTTGGAGCATCAAAGTGGGCCGTGGGTCTGGATTTCCAGGAAAGCG
GAGACCTCGAGGTGCAGGACTGTCGGGGCGAGGTGGCCGAGGCAGGTCAAAGCTGAAAAGTGGAATCGGAGCTGTTGTATTACCTGGGGTGTCTACTGCA
GATATTTCATCAAATAAGGATGATGAAGAAAACTCTATGCACAATACAGTTGTGTTGTTTTCTAGCAGTGACAAGTTCACTTTGAATCAGGATATGTGTG
TAGTTTGTGGCAGTTTTGGCCAAGGAGCAGAAGGAAGATTACTTGCCTGTTCTCAGTGTGGTCAGTGTTACCATCCATACTGTGTCAGTATTAAGATCAC
TAAAGTGGTTCTTAGCAAAGGTTGGAGGTGTCTTGAGTGCACTGTGTGTGAGGCCTGTGGGAAGGCAACTGACCCAGGAAGACTCCTGCTGTGTGATGAC
TGTGACATAAGTTATCACACCTACTGCCTAGACCCTCCATTGCAGACAGTTCCCAAAGGAGGCTGGAAGTGCAAATGGTGTGTTTGGTGCAGACACTGTG
GAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATCTTCCTGTCCAGTCTGCTATCGAAACTA
TAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAATACTGAGGAAGAAGTGGAAAATGTAGCA
GACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGCTGTGAATCTTCACTTGTAGCACAAATTGTCA
CAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACTGAATCAGGGATGACTCAGTTACAGAGCCTCACAGTTACAGT
TCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAATCAGAATAGCGTGGCCGTCCTTCAGACCCCTCCAGACATCCAATCAGAGCAT
TCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAACTTATGGATTGTGATGGAAAATCAGAATCTAGTCCTGAGCGGGAAGCTGTGGATGATGAAA
CTAAGGGAGTGGAAGGAACAGATGGTGTCAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATTTATGGTGCGGCAAAGAAGTCGAACTGG
GCAAGGGAAAACCAAAAGATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGAGATGATGGCTGGAGTGAGCAGTTACCA
GATACTTTAGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGAAAAATAAGCTTGAAGAAACTTTCCCTG
CCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAATCTGTCAGAAGATGGAGCTCAGCTTTT
ATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCAACAAAATCTGGAACTCACGGTCCTGCT
GATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGATGATCTAGCAAAATCAGTTGATCATTCAGATA
TTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCACGACCATTAAGTGAAGAACAGCTAGATGGGATCCTCAGTCC
TGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATATAAAATTCCAGAGCTTGGCGGAAAAGATGTTGAAGACTTATTTACAGCTGTA
CTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAGCCTCCCCCACCAACACAGCTGTTGCCAATACACAATCAGGATGCTTTTTCACGGATGCCTC
TCATGAATGGCCTTATTGGATCCAGTCCTCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAACTTTCTCTGCAATTGCACAATCCTCTTA
TCCTGATGCCAGGGATAAAAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCAGCTCCCACTGTGGAAGGAGAAAATGAC
ACAATGTCGAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTGCCCCAGTTCTCTACACCAATATTAATT
TCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGCAAGCTCACAAGAAAGAGCACCATATGT
GCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGGCAGCAACAGCAAGATAGCATTGATCCC
AGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAATGGAAATTTAGACAGCAAATGCGTCAGAAAA
GTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAGCAGCAGCAGCAACAACAGCAATTTGGTTCTCAGCATCTTCT
GGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTGACACCTCAGCCTGGCAATGGAAATATGTCTCCTGCACAGTCATTCCATAAA
GAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCTACATCTTCAGATGATGTGTTTGTAAAGCCACAAGCTCCACCTCCTCCTCCAGCCCCATCCC
GGATTCCCATCCAGGATAGTCTTTCTCAGGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGGGTCCTCTAACTCACGACCACCATCTCC
AATGGATCCATATGCAAAAATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAATTCTGCTGCACCAGTGGAAAACTGTACA
CCTTTATCATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATTTATGTTCTTCTTCCACGACAAATAATG
ACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATCCCGGTCTCCTGTAGTTTCAGAACAAAC
TGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAAAGACAAAGGATACCTGACTCATATGCA
CGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCTCCATCCTCTCAGGATCCTTATGGATCAGTGT
CACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGACCTATAGATAATTTTTCTCATAATCAGTCAAATGATCCATA
TAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCCCATCCTTCAAGGGCTTTTTCCCAGCCTGGAACCATATCAAGGCCAACATCT
CAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCTGTTGTAGATTCTTATTCCCAATCTTCAGGAACAGCTAGGTCCAATACAGACCCTTACTCTC
AACCTCCTGGAACTCCCCGGCCTACTACTGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTACACAAACTGACTTGTTTGTTACACCTGT
AACAAATCAGAGGCATTCTGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTACTCTCAGCCACCAGCAACACCAAGGCCA
AGGATTTCAGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGCAAGCAGCACAAAACCGAGGACCAGCTT
TACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGACACATTTAGCCGTGTTTCCCCATCTGC
TGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACTGCCCATGATGTTGCTGATCAGCCAAGG
CCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCTGGTGTCTCCCAACTTCCTGGACCTGTGCCAA
CTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAATTGAGACAGCGGCAGAAGTTACGTGAAATCATTCTCCAGCA
GCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGACTCACCCGCAGTGCCTCATCCAGGGCCTCTTCAACACTGGCAACCAGAGAAT
GTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCTGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAGGACCTAGATATGCTGTTTTCCCAAAAG
ATCAGCGTGGACCCTATCCTCCTGATGTTGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCCAGGAGGTAGTCATGGTACCATGCCGAG
TCAAGAGCGCTTCCTTGTGCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTATCTGTAGATATGCCTAGGCCTTTAAAT
AACTCACAAATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACAACATACTGGGCCAAGCATATATTGAAC
TGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATCTTCTAATCTGAGACATGGAAACTTCAT
TCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAGCTACCTGTGCACCCAGATTTGGAACAA
GTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAACCATCCACTAGGTGGTGAATTTTCAGAAGCTC
CTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAGCCTTCTGATGGTCTAGAGGAAAAACTTGATTCTGATGACCC
TTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAAGACTTAGATGATGAAGATCTTGAAAACTTAAATTTAGATACAGAGGATGGC
AAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACTAATGATCCCAACCTGGATGACCTCTTAAGGTCAGGAGAGTTTGATATCATTGCATATACAG
ATCCAGAACTTGACATGGGAGATAAGAAAAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTTAGATAATCAGTGTGTATCTGTTGAACC
AAAAAAAAAGGAACAAGAAAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTTACCAATGAGGTAAAAACGGAAGTACTG
TCTCCAAATTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTCCTTGCTCACAGGCTTCTGCTCACTCAG
ACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGAAACTGCTGGCCCCAGTGCAAATGTCAT
TCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTCTCAAGTTTACTTGCTAATGAGAAATCT
GATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCATGTGTCAAGTTTGCCTCCTTTCATAGCACCGC
CTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAACCATGTTTTTTCTCAGGGTGTGCAGGTAAACCCAGGGCTCAT
TCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCAACTCAAACTGGGCCTCAAACAAGTCAGTCTGGTACCAGTAGCATGTCTGGA
CCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAGAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGCCTCTACTTCTACAGGATCTTTTGGATC
AAGAAAGGCAAGAACAGCAGCAGCAAAGACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCCTAATATTGATTTTGATGCAATTACAGA
TCCTATAATGAAAGCCAAAATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATGCCACCAATGGTGATGAGCAGGTTCCCT
TTTATGGGCCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGGATGGCAGTATAACACATCAGATTTCTA
GGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCAGGAGACCCAACAGCTGCTTCAAATGCA
GCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACTGCCAAGAAAGCTGGGCGTGAATTTCCA
GAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAGATTCGTAAACAACAGAAAGAACATGCTGAAT
TGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATGATGCCCAGTGTCCAGCCCCAGCCACCCCTAATTCCAGGTGC
CACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAGCTTCAGCACCAGCAGCACACAACAGTTATTTCTGGCCATACTAGCCCTGTT
AGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCTCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTCAGCCCCCAATTGCCCAGTTACCAATAA
AAACTTGTACACCAGCCCCAGGGACAGTCTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATTTGATGACAACAATCCCTTTAGTGAAAG
TTTTCAAGAACGGGAACGTAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAGGTAGATAGACAAAGAGCTTTGCAGCAG
AGGATGGAAATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTCCCTTCTACAGTTCCGACTTACCTTGTG
ATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCAGCAGAATATACAACAAGGATCAATTAA
TTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGATTCACCATCAATCCCTGTTGGAAGCCCA
AATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGGCCTTCTTTTACACCTGCTTTACCAGCAGCAC
CTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACACAGTTATCCGGGATCAACCCAATCGCTCATTCAGTTGTATTC
TGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAGAAAAGAGATGATGATGCAGAATCCACCAAGGCTCCATCAACTCCCCATTCA
GATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACTACCTCTACTCCTGCAGTGAGCACACCCAGTGAGCTTCCTCAACAAGCCGACCAAGAGTCGG
TGGAACCAGTCGGCCCATCCACTCCCAATATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCCCAATAGTGATTTCTCACAAGCAACTCC
AAATCAACAGACGTATGCAAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATAAAACTGGAAAAGGCTGAGACAGAGTCC
TGCCCAGGCCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTCCTGTCTCCTCAGCACAGAGTCCTCCCC
ATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAAGTCATCTTCTCTTTTGAATCAAAAACC
TGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAAGGACTGCAAACTTTGGGGGCTCAAATG
CAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGAAGCAAACGGACTCAGAGGACGGGTGAGAAAG
CAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCTAGCACTGACACGTTTACCCACTTGAAACAGCAGAATAATTT
AAGTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCT
GGAAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAG
CTCTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGA
TCGAGATACTCCTGACAGTTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAG
CCTCCAGAACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCA
CTTTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAACAT
TAGCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCCATGGGTTTGGTC
AGTAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAACCCTCCCAGATTAGTGAGCTCTT
ACCGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAG
ACCACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGC
ACCAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCA
TTCCTTCATTGCCACAATCACCTATGAGAGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCA
GCTCCCAGAGAAAGCTTCTCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTG
ACAGTCAAGCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGA
GCATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGATCC
TGTGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGACTTGGATCTGTGG
GTCCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCTCTGAGGAGAGGCCTACAAATGA
AATGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCAT
GTTTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTT
CAGCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGC
TGCTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAG
GCGCTGCCGCTACCTGTGCTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGAC
ATCTCACCTAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAG
AGGATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGAAA
TCCTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGTTTGTGTTAAGGCCTCAC
ACCTTAAACAGCACCAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAGTTTGTTCACTCCAAGTCATCGC
AGTACCGGAAGATGAAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACA
CACCATGGTCATTGAGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTC
CGCATGGATAACGACCATGTGATTGACGCGACGCTCACAGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGA
CTTTTGAGAGAGGACACAAAATTATCATCAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCA
GCACAAGATTCCGTGTCACTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGCTCAGCGGGCGGCTTGTCCCTAGGAAGA
GGCGATTCAACACACCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGACTTTTTGAAAAAGCTTCTGGGAGTTCTGATTTCCTCA
GTCCTTTAGGTTAAAGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTGAAGTGGCCGAGGTTAAACGGAATCACAGAATGGTCCAGCACTTTTGC
TTTTTTTTCTTTTCCTTTTCTTTTTTTTTTGTTTGTTTTTTGTTTTGTTTTTCCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTAGTCTCACTAAGGA
GAAACTTTTACTGGGGCAAAGAGCCGATGGCTGCCCTGCCCCGGGCAGGGGCCTTCCTATGAATGTAAGACTGAAATCACCAGCGAGGGGGACAGAGAGT
GCTGGCCACGGCCTTATTAAAAAGGGGCAGGCCCTCTAACTTCAAAATGTTTTTAAATAAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTC
CTTAGGGATAGAGCTAAGGGATAATAACTTGCACTAAATACATTTAAATACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAG
AGAAACTTTTGTATTTATTATTGAATAAGTGAATGAAGCTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACTAACAAAC
CCTGTTACTTTGTACAGATATGTAAATATTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCTGCAGCAGCTCGGGGGCT
TATAAAATGTTCATAGGGATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACCAAAATTTCAACCTAGAGTGTTGGGGGT
TTTTTGGAAACCGCAGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGGGGCGTATGCTACGACTACAACTTTTATAGCTGTTTTG
GTAATTTAAACTAATTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGTCAGGTTTTTTTGTGCTTACAATTTGTGATAACTGTGAATAACTGCTT
AAAAATACACCCAAATGGAGGCTGAATTTTTTCTTCAGCAAAAGTAGTTTTGATTAGAACTTTGTTTCAGCCACAGAGAATCATGTAAACGTAATAGGAT
CATGTAGCAGAAACTTAAATCTAACCCTTTAGCCTTCTATTTAACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGGAGATGTGATTATGCTTACAGCTG
CAGGACTCTGGCAATAGGGTTTTTGGAAGATGTAATTTTAAAATGTGTTTGTATGAACTGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTG
TTTGCTTGTAGAAACTTAATCAGCATTTTGAACCAGGTTAGCTTTTTATTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGA
AGTTTTGTGTGCACAATTCAAGTGGACTGTAAACTGTTGGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCTTACAGAA
TAAATCAATTGTATATATTTTTCTCTTGATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATATCCTGACATCCTACCAGT
ATTTGTCCTACCGGGTTTTTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTTTGAAGTATACAGAGTGTTATGGGTTTT
GGAATTTGTGGACACAGATTTAGAAGATCACCATTTACAAATAAAATATTTTACATCTATAA
- refseq_MLL3.F1 (forward primer)
- refseq_MLL3.R1 (reverse primer)
- Exon skipping and alternative donor or acceptor
Frame 0
EVRAPAPMCVSACPARSMLPPLPVPAAAPGAAGNARG*AGEEEPEQQRRRRRPRRREPPRRRTGIHV
SFLVTRMSSEEDKSVEQPQPPPPPPEEPGAPAP
SPAAADKRPRGRPRKDGASPFQRARKKPRSRGK
TAVEDEDSMDGLETTETETIVETEIKEQSAEEDA
EAEVDNSKQLIPTLQRSVSEESANSLVSVGVEA
KISEQLCAFCYCGEKSSLGQGDLKQFRITPGFI
LPWRNQPSNKKDIDDNSNGTYEKMQNSAPRKQRG
QRKERSPQQNIVSCVSVSTQTASDDQAGKLWDE
LSLVGLPDAIDIQALFDSTGTCWAHHRCVEWSL
GVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGAT
IKCCEEKCTQMYHYPCAAGAGTFQDFSHIFLLC
PEHIDQAPERSKEDANCAVCDSPGDLLDQFFCT
TCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNC
KQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPT
NGWKCKNCRICIECGTRSSSQWHHNCLICDNCY
QQQDNLCPFCGKCYHPELQKDMLHCNMCKRWVHL
ECDKPTDHELDTQLKEEYICMYCKHLGAEMDRL
QPGEEVEIAELTTDYNNEMEVEGPEDQMVFSEQ
AANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSE
SLDTDSLLIAVSSQHTVNTELEKQISNEVDSED
LKMSSEVKHICGEDQIEDKMEVTENIEVVTHQI
TVQQEQLQLLEEPETVVSREESRPPKLVMESVTL
PLETLVSPHEESISLCPEEQLVIERLQGEKEQK
ENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSI
KLSSETESSFSSSADISKADVSSSPTPSSDLPSH
DMLHNYPSALSSSAGNIMPTTYISVTPKIGMGK
PAITKRKFSPGRPRSKQGAWSTHNTVSPPSWSP
DISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKR
RPRGAGLSGRGGRGRSKLKSGIGAVVLPGVSTA
DISSNKDDEENSMHNTVVLFSSSDKFTLNQDMC
VVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKIT
KVVLSKGWRCLECTVCEACGKATDPGRLLLCDD
CDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHC
GATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNY
REEDLILQCRQCDRWMHAVCQNLNTEEEVENVA
DIGFDCSMCRPYMPASNVPSSDCCESSLVAQIV
TKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTV
PRRKRSKPKLKLKIINQNSVAVLQTPPDIQSEH
SRDGEMDDSREGELMDCDGKSESSPEREAVDDE
TKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTG
QGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLP
DTLVDESVSVTESTEKIKKRYRKRKNKLEETFP
AYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLL
YKTNMNTGFLDPSLDPLLSSSSAPTKSGTHGPA
DDPLADISEVLNTDDDILGIISDDLAKSVDHSD
IGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSP
ELDKMVTDGAILGKLYKIPELGGKDVEDLFTAV
LSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMP
LMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSY
PDARDKNSAFNPMASDPNNSWTSSAPTVEGEND
TMSNAQRSTLKWEKEEALGEMATVAPVLYTNIN
FPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYV
QKARDNRAALRINKVQMSNDSMKRQQQQDSIDP
SSRIDSELFKDPLKQRESEHEQEWKFRQQMRQK
SKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLL
VQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK
ELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPS
RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSP
MDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCT
PLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN
DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQT
AKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYA
RPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSV
SQASRRLSVDPYERPALTPRPIDNFSHNQSNDPY
SQPPLTPHPAVNESFAHPSRAFSQPGTISRPTS
QDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYS
QPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPV
TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRP
RISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPA
LPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSA
ARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPR
PGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVP
TSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQ
QQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPEN
VNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK
DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPS
QERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLN
NSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIE
LRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFI
PRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQ
VPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEA
PLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDP
SVKELDVKDLEGVEVKDLDDEDLENLNLDTEDG
KVVELDTLDNLETNDPNLDDLLRSGEFDIIAYT
DPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEP
KKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVL
SPNSKVESKCETEKNDENKDNVDTPCSQASAHS
DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVI
QASTQLPAQDVINSCGITGSTPVLSSLLANEKS
DNSDIRPSGSPPPPTLPASPSNHVSSLPPFIAP
PGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLI
PGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSG
PQQLMIPQTLAQQNRERPLLLEEQPLLLQDLLD
QERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITD
PIMKAKMVALKGINKVMAQNNLGMPPMVMSRFP
FMGQVVTGTQNSEGQNLGPQAIPQDGSITHQIS
RPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQ
QKYLEEQIGAHRKSKKALSAKQRTAKKAGREFP
EEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAE
LIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGA
TPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPV
RMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPI
KTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSES
FQERERKERLREQQERQRIQLMQEVDRQRALQQ
RMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPC
DFMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSIN
SPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSP
NFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAA
PPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYS
DIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHS
DITAPPTPGISETTSTPAVSTPSELPQQADQES
VEPVGPSTPNMAAGQLCTELENKLPNSDFSQATP
NQQTYANSEVDKLSMETPAKTEEIKLEKAETES
CPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPP
HSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKP
EGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQM
QGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEK
AAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNL
SNPPTPPASLPPTPPPMACQKMANGFATTEELA
GKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLAR
ALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGD
RDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEE
PPEPVPSPIIPILPSTAGKSSESRRNDIKTEPG
TLYFASPFGPSPNGPRSGLISVAITLHPTAAENI
SSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLV
SSHRINPGLEYRQHLLLRGPPPGSANPPRLVSS
YRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALR
PQWCCHCKVVILGSGVRKSFKDLTLLNKDSRES
TKRVEKDIVFCSNNCFILYSSTAQAKNSENKES
IPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQ
LPEKASPPASPPIAFPPAFEAAQVEAKPDELKV
TVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKW
SIHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDP
VPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLW
VHLNCALWSTEVYETQAGALINVELALRRGLQM
KCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCM
FFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYV
QRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQ
LLPQQMQAFHSPKALFPVGYEASRLYWSTRYANR
RCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSD
ISPKGVWDKILEPVACVRKKSEMLQLFPAYLKG
EDLFGLTVSAVARIAESLPGVEACENYTFRYGRN
PLMELPLAVNPTGCARSEPKMSAHVKRFVLRPH
TLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSS
QYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKH
TMVIEYIGTIIRNEVANRKEKLYESQNRGVYMF
RMDNDHVIDATLTGGPARYINHSCAPNCVAEVV
TFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQ
HKIPCHCGAVNCRKWMN*NAFLASSAGGLSLGR
GDSTHHWNFADRKRFLFSVL*LFEKASGSSDFL
SPLG*SSARRKLTEAAFLKWPRLNGITEWSSTFA
FFSFPFLFFLFVFCFVFPLWVGFIVLVF*SH*G
ETFTGAKSRWLPCPGQGPSYECKTEITSEGDRE
CWPRPY*KGAGPLTSKCF*IK*TPLNKECTEMTS
LGIELRDNNLH*IHLNT*FHESVYCSF*FL*NK
RNFCIYY*ISE*SYF*IKLEESQAAAVTCRTNK
PCYFVQICKYFEKKYSIKIVIDQMLPGSAAARGL
IKCS*GCYNIILCYKICHYNYVITKIST*SVGG
FLETAVY*YSMVLYTLLLTERGVCYDYNFYSCF
GNLN*FFHIILLHPYFFSQVFLCLQFVITVNNCL
KIHPNGG*IFSSAKVVLIRTLFQPQRIM*T**D
HVAET*I*PFSLLFNTKI*KS*KKKGDVIMLTA
AGLWQ*GFWKM*F*NVFV*TVCLHFFNKKNTVLC
LLVET*SAF*TRLAFYFVLKILVLTLHRLSIK*
SFVCTIQVDCKLLVYSVMQF*TCIWHDVFLSYR
INQLYIFFS**IAV*NLFPEYFSSLVQYPDILPV
FVLPGFCCFLFCIIVSNVGKN*IF*SIQSVMGF
GICGHRFRRSPFTNKIFYIY
Frame 1
RCARPRRCV*VRVLLAPCCRLSRYLLLLPGLREMREAEPGRRNPSSSGGGGGRGGGSPPGGGPGSM
CLSW*LGCRRRRTRAWSSRSRRHHPPRSLEPRPR
APQPQTKDLGAGLAKMALPLSREPERNLEVGGK
LQWKMRTAWMGWRQQKQKRLWKQKSKNNLQKRM
LKQKWITANS*FQLFSDLCLRNRQTPWSLLV*KP
KSVNSSALFVTVGKKVP*DKET*NNSE*RLDLS
CHGETNLLTRRTLMTTAMEPMRKCKTQHHENKE
DREKNDLLSRI*YLV*V*APRQLQMIKLVNCGMN
SVWLGFQMPLISKPYLILQALVGLITVVWSGH*
EYARWKNHC**TWTKLLSQGAQNDVHFVSTLEP
LSNAVKRNVPRCIIILVLQEPAPFRISVTSSCFV
QNTLTKLLKDRRKMQTVQCATARETS*ISSFVL
LVVSTIMECAWI*RLLH*NVQVGNVLSAKCART
ANNREKIARC*CVIRVTKGIILFVFNQL*NQYQP
MAGNAKIAEYV*SVAHGLVLSGTTIA*YVTIVT
NSRITYVPSVGSVIIQNCRKTCFIVICAKGGFT
*SVTNQQIMNWILSSKKSISACIVNTWELRWIVY
SQVRKWR*LSSLQIITMKWKLKALKIKWYSQSR
QLIKMSTVRSPLLELFQMRFKSTLKSNRRVIPQ
KVLTQIVFLLLYHPNIQ*ILNWKNRFLMKLIVKT
*KCLLK*SIFVAKIKLKIKWK*QKTLKSLHTRS
LCSKNNCSC*RNLKQWYPEKNQGLQN*SWNLSL
FH*KP*CPHMRKVFHYVLRNSWL*KGYKEKRNRK
KILNFLLD*WTLK*LLQLRVV*KMFHTKEANL*
SYHLRQSHHFHHQQT*ARQMCLPPQHLLQTCLR
MTCCIITLQLLVPLLETSCQQLTSQSLQKLAWVN
QLLLRENFLLVDLGPNRGLGVPIIQ*AHLPGPQ
TFQKVGKFLNPGSFLAVPFGASKWAVGLDFQES
GDLEVQDCRGEVAEAGQS*KVESELLYYLGCLLQ
IFHQIRMMKKTLCTIQLCCFLAVTSSL*IRICV
*FVAVLAKEQKEDYLPVLSVVSVTIHTVSVLRS
LKWFLAKVGGVLSALCVRPVGRQLTQEDSCCVMT
VT*VITPTA*TLHCRQFPKEAGSANGVFGADTV
EQHLQV*DVNGRTITHSALLVQAYLPVQSAIET
IEKKILFCNVDNVIDGCMQFVRT*ILRKKWKM*Q
TLVLIVACADPICLRLMCLPQTAVNLHL*HKLS
QK*KS*THPRLIPRMVCV*LNQG*LSYRASQLQ
FQEENGQNQN*N*RL*IRIAWPSFRPLQTSNQSI
QGMVKWMIVEKENLWIVMENQNLVLSGKLWMMK
LREWKEQMVSKREKGNHTDQVLVDLWCGKEVEL
GKGKPKDL*SEKIPQALFPSSYLAEMMAGVSSYQ
IL*LMNLFLLLKALKK*RRDTEKGKISLKKLSL
PIYKKLSLEKIF*IQVDKAR*V*IICQKMELSF
YIKQT*TQVSWILP*IHYLVHPRLQQNLELTVLL
MTH*LIFLKF*TQMMTFLE*FQMI*QNQLIIQI
LVLSLMILPLCLSQMSIRVHDH*VKNS*MGSSV
LN*TKWSQMEQFLENYIKFQSLAEKMLKTYLQLY
LVLRTLSQLHCHSLPHQHSCCQYTIRMLFHGCL
S*MALLDPVLISHIILCHLEADWELSLQLHNPL
ILMPGIKIQPLIQWQVILTTLGHHQLPLWKEKMT
QCRMPREARLSGRKRRLWVKWQLLPQFSTPILI
SPT*RKNSLIGLLE*SKLPNCGEKQAHKKEHHM
CKKPEITELLYALIKYRCQMIP*KGSNSKIALIP
ALVLIRSFLKIL*SKENQNMNRNGNLDSKCVRK
VSSKLKLKPHRNLNR*KMSSSSSNNSNLVLSIF
WCSLVQIHQVVGYRVP*HLSLAMEICLLHSHSIK
NCLQNSHPVPLRLHLQMMCL*SHKLHLLLQPHP
GFPSRIVFLRLRLLSHPHRKCFHLGPLTHDHHL
QWIHMQKWLVPLDHLLWAIVFPEEILLHQWKTVH
LYHRYLGPFK*MRQQQIGHPLSEIYVLLPRQIM
TPMQNLQTHLGL**QINFPNPWAYPGLL*FQNK
LQKAL*QLEPVITLLNHLLGQMCFKDKGYLTHMH
DPC*HLHLLIVVLDLLRLQCNLLHPLRILMDQC
HRHQGDCLLTLMKGLL*HQDL*IIFLIISQMIH
IVSLPLPHIQQ*MNLLPILQGLFPSLEPYQGQHL
RTHTPNPQELHDLL*ILIPNLQEQLGPIQTLTL
NLLELPGLLLLTHIVSSPKPQDHLHKLTCLLHL
*QIRGILIHMLILLEHQDLEFLSLTLSHQQHQGQ
GFQRVLLGPQ*QDQSSCQIRILSCKQHKTEDQL
YLARW*GHLIHVPRHLGPLDLVFQTHLAVFPHL
LPVIPMISLQ*LQDLSLTLLEQVKLPMMLLISQG
LDQRGASVHLQTLQCTPKASSSLVSPNFLDLCQ
LQE*LIHRIL*IWPKQIQRN*DSGRSYVKSFSS
SNSRRRLQVDRRRGHRTHPQCLIQGLFNTGNQRM
LTRLSPDPHLPILGTLGLLLPLL*DLDMLFSQK
ISVDPILLMLLVWG*DLMDLDLDFQEVVMVPCR
VKSASLCLLSKYRDLEFLHS*EDQYL*ICLGL*I
THK*IIQLDFLSIFHHRACQFSSTTYWAKHILN
*DIGLLTEGNGCLSVLHLAAL*RHLLI*DMETS
FPGQTFRALDTQTPCDDLPRVYLISYLCTQIWNK
CHHLNKSKVILSIHLLWS*GL*TIH*VVNFQKL
LCQHLYRLKQRLIIYR*PPSLLMV*RKNLILMT
LL*RNWMLKTLRGLKSKT*MMKILKT*I*IQRMA
R*LNWIL*IIWKLMIPTWMTS*GQESLISLHIQ
IQNLTWEIRKACLMRN*TFQLMIS*IISVYLLN
QKKRNKKTKLWFSLINIHHRKNPLLPMR*KRKYC
LQILRWNPNVKLKKMMRIKIMLTLLAHRLLLTQ
T*MMEKRLLCILVIQIYLRKEPIEKLLAPVQMS
FRHPLNYLLKM**TLVA*LDQLQFSQVYLLMRNL
IIQTLGHRGLHHHQLCRPPHPIMCQVCLLS*HR
LAVFWIMP*ILM*Q*SLG*TMFFLRVCR*TQGS
FQVNQQLTTVWGQENLQLKLGLKQVSLVPVACLD
PNS**FLKH*HSRIERGPFF*KNSLYFYRIFWI
KKGKNSSSKDRCKP*FVSDQNRSSLILILMQLQ
IL**KPKWWPLKV*IK*WHKTIWACHQW**AGSL
LWARW*LEHRTVKDRTLDHRPFLRMAV*HIRFL
GLILQILVQALSMIHSVSSMKSGSRRPNSCFKC
SRSILKNKLVLTENLRRPFQLNNVLPRKLGVNFQ
RKMQNNSSMLLNSKAWFRNS*NRFVNNRKNMLN
*LKIIGSNSSSNVQWPHLP*CPVSSPSHP*FQV
PLHPP*ANPPFPWCHSSFSTSSTQQLFLAILALL
ECPVYLDGNPTVLLPTCPSILLEFSPQLPSYQ*
KLVHQPQGQSQMQIHRVDHHLG*NLMTTIPLVK
VFKNGNVRNVYENSKRDNGSNSCRR*IDKELCSR
GWKWSSMVWWALR*VVVGHLCPRFPSTVPTYLV
ILCNL*DPFSSLHNTNSKWGRFYSSRIYNKDQL
IHPPPKLSCRLMSEGR*ALLHLFLIHHQSLLEAQ
IFLL*SRDMEIFLGPASSSPQ*GLLLHLLYQQH
LQ*LIAVSHVAKILL*PMDTVIRDQPNRSFSCI
LI*SQRKKGKRKEQERRKEMMMQNPPRLHQLPIQ
I*LPHRLQASQKLPLLLQ*AHPVSFLNKPTKSR
WNQSAHPLPIWQQASYVQN*RTNCPIVISHKQL
QINRRMQIQK*TSSPWKPLPKQKR*NWKRLRQSP
AQAKRSLNWRNRMVVR*KETL*PVLSPQHRVLP
ILLGPLLPKETQGMNF*NTC*KIKSHLLF*IKN
LRAVFVQKMTVQRIIN*LRSRTQLKDCKLWGLKC
KVVLDVATSCQKQMEEVKPRNSEANGLRGRVRK
QHLAQRKGKRTKRRNKLCTLALTRLPT*NSRII
*VILQHPLPLFLLHHLLWLVRRWPMVLQQLKNLL
EKPEC**AMKLPKL*DLNHFSCPSDPRTTCWPE
LLLRAPRQLMCQPPSQHHLITIRKN*GYRITVV
IEILLTVLFPHPLLRVWLG*K*AGIQICHWSRRS
LQNRCRPPSFQFFLALLGKVQNQEGMTSKLSQA
LYILRHLLVLPQMVPDQVLYL*QLLCILQLLRT
LAVLWLHFPTFFTSESLTAMRLAVLQMSHPWVWS
VATESTRVWSIDSIYFSVGLRQDLQTLPD**AL
TG*SSLMYHFLQQAMVFLDIRILVMVLQKAQHS
DHSGVVIVKWLFLEVVCGNLSKI*PF*TRIPEKA
PRG*RRTLSSVVITALFFIHQLHKRKTQKTRNP
FLHCHNHL*EKRLPKHFISTATTSPLWMCTVSP
SSQRKLLPLPHHPSPSLLLLKQPKSRPSQMS*R*
QSS*SLG*ELSMVGLKIAGRSIKNGEE*NGRSG
AFIL*SLRGHLNHLVRMK*MNF*RNWALPLNLI
LCPKTIGNVAFVMKKVMD*QMDQQGYSTLTWICG
ST*TALCGPRRSMRLRLVP**MWS*L*GEAYK*
NVSSVTRRVPLVDATDFDAPTFITSLAPLKHNA
CFLRTKLCFAPCTNQREFMSKN*VTLQSSGGSMF
SVMRCDRLLASCNEENGTIPFAWVASSSTQLVS
CFHSRCKHSILLKHSSLWAMKPAGCTGALAMPI
GAAATCAPLRRRMGAQCLSSGLWNKAMKTWF*VT
SHLKVSGIRFWSLWHV*EKSLKCSSFSQRI*KE
RICLA*PSLQWHA*RNHFLGLRHVKIIPSDTAE
ILSWNFLLPLTPQVVPVLNLK*VPMSRGLC*GLT
P*TAPAPQSHFRAQSLEN*THLIVNSLFTPSHR
STGR*KLNGNPMCIWHGLGFRGWACMLLETLRN
TPWSLSTSGLSFETK*PTGKRSFMSLRTVVCTCS
AWITTM*LTRRSQEGPQGISTIRVHLIVWLKW*
LLREDTKLSSAPVGESRKEKSSAMTISLTLKMT
STRFRVTVEL*TAGSG*TEMHSLLAQRAACP*EE
AIQHTIGILQTERDFCFLFYDFLKKLLGVLISS
VL*VKAAPGGS*QKQRS*SGRG*TESQNGPALL
LFFLFLFFFFCLFFVLFFPCGWVSLFWFSSLTKE
KLLLGQRADGCPAPGRGLPMNVRLKSPARGTES
AGHGLIKKGQAL*LQNVFK*SRHH*TRNVLK*L
P*G*S*GIITCTKYI*ILDSMSQFIVVFDFCKIR
ETFVFIIE*VNEAIFK*S*KKAKLLLLPAELTN
PVTLYRYVNILRKNTV*K*LLTKCYQALQQLGG
L*NVHRDVTI*FCVIKYAIIIM**PKFQPRVLGV
FWKPQSISTQWFYTPYF*QSGAYATTTTFIAVL
VI*TNFFILYCCIPTSSVRFFCAYNL**L*ITA
*KYTQMEAEFFLQQK*F*LELCFSHRESCKRNRI
M*QKLKSNPLAFYLTQKFEKVKKKKEM*LCLQL
QDSGNRVFGRCNFKMCLYELFVYISLIKKTLFC
VCL*KLNQHFEPG*LFILYLKFWY*HFTG*V*NE
VLCAQFKWTVNCWYIQ*CSSELVYGMMYFYLTE
*INCIYFSLDK*LYEICFLNIFLLLYNILTSYQ
YLSYRVFVVFCSV**YLMLAKIEFFEVYRVLWVL
EFVDTDLEDHHLQIKYFTSI
Frame 2
GARARADVCECVSCSLHVAASPGTCCCSRGCGKCERLSRGGGTRAAAAAAAAAAAGAPQEEDRDPC
VFPGD*DVVGGGQERGAAAAAATTPRGAWSPGP
EPRSRRQKTSGPASQRWRFPFPESQKETSK*GEN
CSGR*GQHGWAGDNRNRNDCGNRNQRTICRRGC
*SRSG*QQTANSNSSAICV*GIGKLPGLCWCRS
QNQ*TALRFLLLWGKKFLRTRRLKTIQNNAWIYL
AMEKPTF*QEGH**QQQWNL*ENAKLSTTKTKR
TEKRTISSAEYSILCKCKHPDSFR*SSW*TVG*
TQSGWASRCH*YPSLI*FYRHLLGSSPLCGVVTR
SMPDGRTIVSERGQSCCLREHRTMCIL*APWSH
YQML*REMYPDVSLSLCCRSRHLSGFQSHLPAL
SRTH*PSS*KIEGRCKLCSVRQPGRPLRSVLLYY
LWSALSWNVPGYSGYSIKTCRLAMS*VQSVPEL
QTIGRR*QDASV*YV*QRVSYFLSSTSYEISTN
QWLEMQKLQNMYRVWHTV*FSVAPQLPDM*QLLP
TAG*LMSLLWEVLSSRIAERHASL*YVQKVGSP
RV*QTNRS*TGYSAQRRVYLHVL*TPGS*DGSF
TAR*GSGDS*AHYRL*Q*NGS*RP*RSNGILRAG
S**RCQRSGVHSWNCSRCGSSPH*RATEESSLR
KS*HR*SSYCCIIPTYSEY*IGKTDF**S***R
PENVF*SEAYLWRRSN*R*NGSDRKH*SRYTPDH
CAARTTAVVRGT*NSGIQRRIKASKISHGICHS
STRNLSVPT*GKYFIMS*GTVGYRKATRRKGTE
RKF*TFYWIDGL*NDSYN*GLCERCFIPRRQIYK
VII*DRVIIFIISRHKQGRCVFLPNTFFRLAFA
*HAA*LPFSS*FLCWKHHANNLHLSHSKNWHG*
TSYY*EKIFSW*TSVQTGGLEYP*YSEPTFLVPR
HFRRSGNF*TQAASWQCHLEHQSGPWVWISRKA
ETSRCRTVGARWPRQVKAEKWNRSCCITWGVYC
RYFIK*G**RKLYAQYSCVVF*Q*QVHFESGYVC
SLWQFWPRSRRKITCLFSVWSVLPSILCQY*DH
*SGS*QRLEVS*VHCV*GLWEGN*PRKTPAV**
L*HKLSHLLPRPSIADSSQRRLEVQMVCLVQTLW
SNICRSKM*MAEQLHTVRSLCKLIFLSSLLSKL
*RRRSYSAM*TM**MDACSLSELKY*GRSGKCS
RHWF*L*HVQTLYACV*CAFLRLL*IFTCSTNCH
KSKRARPTQDLYPGWCVFD*IRDDSVTEPHSYS
SKKKTVKTKIEIEDYKSE*RGRPSDPSRHPIRA
FKGW*NG**SRRRTYGL*WKIRI*S*AGSCG**N
*GSGRNRWCQKEKKETIQTRYWWIYGAAKKSNW
ARENQKICDQKRFLRLYFRAVTLQR*WLE*AVT
RYFS**ICFCY*KH*KNKEEIPKKEK*A*RNFPC
LFTRSFLWKRSSRYK*TKQDKFR*SVRRWSSAF
I*NKHEHRFLGSFLRSTT*FILGSNKIWNSRSC
**PIS*YF*SFKHR**HSWNNFR*SSKIS*SFRY
WSCH**SFLFASAKCQSEFTTIK*RTARWDPQS
*TRQNGHRWSNSWKII*NSRAWRKRC*RLIYSC
T*SCEHSANSIATASPTNTAVANTQSGCFFTDAS
HEWPYWIQSSSPT*FFATWKRTGNFLCNCTILL
S*CQG*KFSL*SNGK*S*QLLDIISSHCGRRK*
HNVECPEKHA*VGERGGSG*NGNCCPSSLHQY*F
PQLKGRIP*LDY*SEANCQIVEKSKLTRKSTIC
AKSQR*QSCFTH**STDVK*FHEKAATAR*H*S
QLSY*FGAF*RSFKAKRIRT*TGMEI*TANASEK
*AAS*N*SHTET*TGEK*AAAAATTAIWFSASS
GAVWFRYTK*WDTESLDTSAWQWKYVSCTVIP*
RTVYKTATQYPYVYIFR*CVCKATSSTSSSSPIP
DSHPG*SFSGSDFSATLTASVFTWVL*LTTTIS
NGSICKNGWYPSTTSCGP*FFQKKFCCTSGKLY
TFIIGI*APSNE*DNSK*AIPCQRFMFFFHDK**
PLCKTSRHT*ACDDRSISQILGPIPVSCSFRTN
CKRPYSSWNQ*SLY*TIS*GRCVSKTKDT*LIC
TTLVDTCTS**WSWTF*DSNATSSILSGSLWISV
TGIKAIVC*PL*KACFDTKTYR*FFS*SVK*SI
*SASPYPTSSSE*IFCPSFKGFFPAWNHIKANI
SGPILPTPRNSTTCCRFLFPIFRNS*VQYRPLLS
TSWNSPAYYC*PI*SAAPNPKTIYTN*LVCYTC
NKSEAF*SICSSSWNTKTWNFCPLLSATSNTKA
KDFRGFY*VLNDKTSPHAKSGSFPASSTKPRTSF
TWPVGKAT*YMFPDT*APWTWSFRHI*PCFPIC
CP*SL*SVSNDSKISV*LFWNKSNCP*CC*SAK
AWIRGELLCIFKLSNALPRPAVLWCLPTSWTCAN
FRSN*YTEYCKYGPSRYREIETAAEVT*NHSPA
ATAEEDCRSTGEGVTGLTRSASSRASSTLATRE
C*PGFHQTPTSLSWEH*VSCCPSFRT*ICCFPKR
SAWTLSS*CC*YGDETSWI*IWISRR*SWYHAE
SRALPCASSANTGIWSFSTAKKISICRYA*AFK
*LTNE*SSWTSSAFFTTELASSAAQHTGPSIY*T
ET*GS*RKATAAFQCSTWQRCRGIF*SETWKLH
SPARLSGP*THRPHATTSPGST*SATCAPRFGT
SATISTRARSFCPFIFYGHEDSEPSTRW*IFRSS
FVNICTV*NNV**FTDNHPAF*WSRGKT*F**P
FCEGTGC*RP*GG*SQRLR**RS*KLKFRYRGW
QGS*IGYFR*FGN**SQPG*PLKVRRV*YHCIYR
SRT*HGR*EKHV**GTRPSN***VR*SVCIC*T
KKKGTRKQNSGSL**TFTTEKIHCYQ*GKNGST
VSKF*GGIQM*N*KK**E*R*C*HSLLTGFCSLR
PK*WRKDFFASL*SRSI*EKNQSRNCWPQCKCH
SGIHSTTCSRCNKLLWHNWINSSSLKFTC**EI
**FRH*AIGVSTTTNSAGLPIQSCVKFASFHSTA
WPCFG*CHEF*CDSSL*GKPCFFSGCAGKPRAH
SRSINS*PQSGDRKTCNSNWASNKSVWYQ*HVW
TPTANDSSNISTAE*REAPSSRRTASTSTGSFGS
RKARTAAAKTDASHDSSAIRTVLP*Y*F*CNYR
SYNESQNGGP*RYK*SDGTKQSGHATNGDEQVP
FYGPGGNWNTEQ*RTEPWTTGHSSGWQYNTSDF*
A*SSKFWSRLCQ*FTA*AV*RVAPGDPTAASNA
AEVS*RTNWCSQKI*EGPFS*TTYCQESWA*IS
RGRCRTTQACY*TAKHGSETARTDS*TTERTC*I
D*RLSDQTAAAMCNGPTYHDAQCPAPATPNSRC
HSTHHEPTHLSHGATAASAPAAHNSYFWPY*PC
*NAQFTWMATQQCSCPPAPQSS*NSAPNCPVTNK
NLYTSPRDSLKCKSTEWTTTSGRI**QQSL**K
FSRTGT*GTFTRTARETTDPTHAGGR*TKSFAA
EDGNGAAWYGGL*DK***DICVPDSLLQFRLTL*
FYATSRTPSAVSTTPTANGAGFTAAEYTTRIN*
FTLHPNFHAD**AKAGRPSFICS*FTINPCWKP
KFFFCEAGTWKSFWDQLPAVPSEAFFYTCFTSST
SSS**QSPMWPRFYYNPWTQLSGINPIAHSVVF
*YNPRGKREKEKNKKEEKR**CRIHQGSINSPF
RYNCPTDSRHLRNYLYSCSEHTQ*ASSTSRPRVG
GTSRPIHSQYGSRPAMYRIREQTAQ**FLTSNS
KSTDVCKFRSRQALHGNPCQNRRDKTGKG*DRV
LPRPRGA*IGGTEW**GRRKRCSLSCLLSTESSP
FCWGPCCQRRLRE*TSETLVEK*KVIFSFESKT
*GQYLFRR*LYKG**TS*EAEPS*RTANFGGSN
ARWFWMWQPVAKNRWRK*NQETAKQTDSEDG*ES
STSLKEKEKGRRGETSYVL*H*HVYPLETAE*F
K*SSNTPCLSSSYTTSYGLSEDGQWFCNN*RTC
WKSRSVSEP*SYQNSRT*TISAALQTPGRLVGPS
SCSGPQDS*CASLPPNTTS*QSGRIKDTGSLW*
SRYS*QFCSLILS*ECGWGRSEQVSRSVIGQGG
ASRTGAVPHHSNSS*HCWEKFRIKKE*HQN*ARH
FIFCVTFWSFPKWSQIRSYICSNYSASYSC*EH
*QCCGCIFRPSSRPNP*QL*G*QCSRCPIHGFG
Q*PQNQPGFGVSTAFTSPWASARICKPSQISELL
PAEAA*CTISSNKQWSFWI*GF*SWYCRKRSTQ
TTVVLSL*SGYSWKWCAEIFQRSDPFEQGFPRK
HQEGREGHCLL***LLYSLFINCTSEKLRKQGIH
SFIATITYERNAFQSISSVQQQHLHFGCALSPP
APRESFSPCLTTHRLPSCF*SSPSRGQAR*AEG
DSQAEASAKSCPWWV*RLQAAQ*KMERNEMEEVE
HSYCNP*GDI*TTL*G*NR*ISKEIGHFP*T*S
CAQRLSEMLLLS*RR*WIDRWTSKATQP*LGSV
GPLELRSVVHGGL*DSGWCLNKCGASSEERPTNE
MCLLSQDGCH*WMPQISMHQHLSLHLRH*STMH
VF*GQNYALPHAQTKGNS*ARIKLLCSLQEGLC
SA**GATDC*HRATRRTGPYLSRG*PHLPHNWSA
ASTADASIPFS*STLPCGL*SQPAVLEHSLCQ*
ALPLPVLH*GEGWAPSVCHQDCGTRP*RPGSK*
HLT*RCLG*DFGACGMCEKKV*NAPAFPSVFKRR
GSVWPDRLCSGTHSGITSWG*GM*KLYLPIRPK
SSHGTSSCR*PHRLCPF*T*NECPCQEVCVKAS
HLKQHQHLKVISEHSHWRTERTL**TVCSLQVIA
VPEDEN*MEIQCVSGTVSDSGAGPVCCSRH*ET
HHGH*VHRDYHSKRSSQQEREAL*VSEPWCVHV
PHG*RPCD*RDAHRRARKVYQPFVCT*LCG*SGD
F*ERTQNYHQLQSENPERRRALL*L*V*L*R*P
AQDSVSLWSCELPEVDELKCIPC*LSGRLVPRK
RRFNTPLEFCRQKEIFVFCFMTF*KSFWEF*FPQ
SFRLKQRQEEADRSSVPEVAEVKRNHRMVQHFC
FFFFSFSFFFVCFLFCFSLVGGFHCFGFLVSLR
RNFYWGKEPMAALPRAGAFL*M*D*NHQRGGQRV
LATALLKRGRPSNFKMFLNKVDTTEQGMY*NDF
LRDRAKG**LALNTFKYLIP*VSLL*FLISVK*
EKLLYLLLNK*MKLFLNKVRRKPSCCCYLQN*QT
LLLCTDM*IF*EKIQYKNSY*PNATRLCSSSGA
YKMFIGMLQYNFVL*NMPL*LCNNQNFNLECWG
FFGNRSLLVLNGFIHLTSDRAGRMLRLQLL*LFW
*FKLIFSYYIVASLLLQSGFFVLTICDNCE*LL
KNTPKWRLNFFFSKSSFD*NFVSATENHVNVIG
SCSRNLNLTL*PSI*HKNLKKLKKKRRCDYAYSC
RTLAIGFLEDVILKCVCMNCLFTFL**KKHCFV
FACRNLISILNQVSFLFCT*NSGTDTSQAKYKM
KFCVHNSSGL*TVGIFSDAVLNLYMA*CIFILQN
KSIVYIFLLINSCMKFVS*IFFFSCTIS*HPTS
ICPTGFLLFSVLYNSI*CWQKLNFLKYTECYGF
WNLWTQI*KITIYK*NILHL*
Sequence NM_021230
AAAATTCCTTAGTTGCTGGCTTTGACCTTTTATGTTGCTGAGTTTTACACATCTATTTTCTCAACTGCCATATCCTAGGGGGCTTGGAGTACCCATAATACAGTGAGCCCACCTTCCTGGTCCCCAGACATTTCAGAAGGTCGGGAAATTTTTAAACCCAGGCAGCTTCCTGGCAGTGCCATTTGGAGCATCAAAGTGGG
CCGTGGGTCTGGATTTCCAGGAAAGCGGAGACCTCGAGGTGCAGGACTGTCGGGGCGAGGTGGCCGAGGCAGGTCAAAGCTGAAAAGTGGAATCGGAGCT
GTTGTATTACCTGGGGTGTCTACTGCAGATATTTCATCAAATAAGGATGATGAAGAAAACTCTATGCACAATACAGTTGTGTTGTTTTCTAGCAGTGACA
AGTTCACTTTGAATCAGGATATGTGTGTAGTTTGTGGCAGTTTTGGCCAAGGAGCAGAAGGAAGATTACTTGCCTGTTCTCAGTGTGGTCAGTGTTACCA
TCCATACTGTGTCAGTATTAAGATCACTAAAGTGGTTCTTAGCAAAGGTTGGAGGTGTCTTGAGTGCACTGTGTGTGAGGCCTGTGGGAAGGCAACTGAC
CCAGGAAGACTCCTGCTGTGTGATGACTGTGACATAAGTTATCACACCTACTGCCTAGACCCTCCATTGCAGACAGTTCCCAAAGGAGGCTGGAAGTGCA
AATGGTGTGTTTGGTGCAGACACTGTGGAGCAACATCTGCAGGTCTAAGATGTGAATGGCAGAACAATTACACACAGTGCGCTCCTTGTGCAAGCTTATC
TTCCTGTCCAGTCTGCTATCGAAACTATAGAGAAGAAGATCTTATTCTGCAATGTAGACAATGTGATAGATGGATGCATGCAGTTTGTCAGAACTTAAAT
ACTGAGGAAGAAGTGGAAAATGTAGCAGACATTGGTTTTGATTGTAGCATGTGCAGACCCTATATGCCTGCGTCTAATGTGCCTTCCTCAGACTGCTGTG
AATCTTCACTTGTAGCACAAATTGTCACAAAAGTAAAAGAGCTAGACCCACCCAAGACTTATACCCAGGATGGTGTGTGTTTGACTGAATCAGGGATGAC
TCAGTTACAGAGCCTCACAGTTACAGTTCCAAGAAGAAAACGGTCAAAACCAAAATTGAAATTGAAGATTATAAATCAGAATAGCGTGGCCGTCCTTCAG
ACCCCTCCAGACATCCAATCAGAGCATTCAAGGGATGGTGAAATGGATGATAGTCGAGAAGGAGAACTTATGGATTGTGATGGAAAATCAGAATCTAGTC
CTGAGCGGGAAGCTGTGGATGATGAAACTAAGGGAGTGGAAGGAACAGATGGTGTCAAAAAGAGAAAAAGGAAACCATACAGACCAGGTATTGGTGGATT
TATGGTGCGGCAAAGAAGTCGAACTGGGCAAGGGAAAACCAAAAGATCTGTGATCAGAAAAGATTCCTCAGGCTCTATTTCCGAGCAGTTACCTTGCAGA
GATGATGGCTGGAGTGAGCAGTTACCAGATACTTTAGTTGATGAATCTGTTTCTGTTACTGAAAGCACTGAAAAAATAAAGAAGAGATACCGAAAAAGGA
AAAATAAGCTTGAAGAAACTTTCCCTGCCTATTTACAAGAAGCTTTCTTTGGAAAAGATCTTCTAGATACAAGTAGACAAAGCAAGATAAGTTTAGATAA
TCTGTCAGAAGATGGAGCTCAGCTTTTATATAAAACAAACATGAACACAGGTTTCTTGGATCCTTCCTTAGATCCACTACTTAGTTCATCCTCGGCTCCA
ACAAAATCTGGAACTCACGGTCCTGCTGATGACCCATTAGCTGATATTTCTGAAGTTTTAAACACAGATGATGACATTCTTGGAATAATTTCAGATGATC
TAGCAAAATCAGTTGATCATTCAGATATTGGTCCTGTCACTGATGATCCTTCCTCTTTGCCTCAGCCAAATGTCAATCAGAGTTCACGACCATTAAGTGA
AGAACAGCTAGATGGGATCCTCAGTCCTGAACTAGACAAAATGGTCACAGATGGAGCAATTCTTGGAAAATTATATAAAATTCCAGAGCTTGGCGGAAAA
GATGTTGAAGACTTATTTACAGCTGTACTTAGTCCTGCGAACACTCAGCCAACTCCATTGCCACAGCCTCCCCCACCAACACAGCTGTTGCCAATACACA
ATCAGGATGCTTTTTCACGGATGCCTCTCATGAATGGCCTTATTGGATCCAGTCCTCATCTCCCACATAATTCTTTGCCACCTGGAAGCGGACTGGGAAC
TTTCTCTGCAATTGCACAATCCTCTTATCCTGATGCCAGGGATAAAAATTCAGCCTTTAATCCAATGGCAAGTGATCCTAACAACTCTTGGACATCATCA
GCTCCCACTGTGGAAGGAGAAAATGACACAATGTCGAATGCCCAGAGAAGCACGCTTAAGTGGGAGAAAGAGGAGGCTCTGGGTGAAATGGCAACTGTTG
CCCCAGTTCTCTACACCAATATTAATTTCCCCAACTTAAAGGAAGAATTCCCTGATTGGACTACTAGAGTGAAGCAAATTGCCAAATTGTGGAGAAAAGC
AAGCTCACAAGAAAGAGCACCATATGTGCAAAAAGCCAGAGATAACAGAGCTGCTTTACGCATTAATAAAGTACAGATGTCAAATGATTCCATGAAAAGG
CAGCAACAGCAAGATAGCATTGATCCCAGCTCTCGTATTGATTCGGAGCTTTTTAAAGATCCTTTAAAGCAAAGAGAATCAGAACATGAACAGGAATGGA
AATTTAGACAGCAAATGCGTCAGAAAAGTAAGCAGCAAGCTAAAATTGAAGCCACACAGAAACTTGAACAGGTGAAAAATGAGCAGCAGCAGCAGCAACA
ACAGCAATTTGGTTCTCAGCATCTTCTGGTGCAGTCTGGTTCAGATACACCAAGTAGTGGGATACAGAGTCCCTTGACACCTCAGCCTGGCAATGGAAAT
ATGTCTCCTGCACAGTCATTCCATAAAGAACTGTTTACAAAACAGCCACCCAGTACCCCTACGTCTACATCTTCAGATGATGTGTTTGTAAAGCCACAAG
CTCCACCTCCTCCTCCAGCCCCATCCCGGATTCCCATCCAGGATAGTCTTTCTCAGGCTCAGACTTCTCAGCCACCCTCACCGCAAGTGTTTTCACCTGG
GTCCTCTAACTCACGACCACCATCTCCAATGGATCCATATGCAAAAATGGTTGGTACCCCTCGACCACCTCCTGTGGGCCATAGTTTTTCCAGAAGAAAT
TCTGCTGCACCAGTGGAAAACTGTACACCTTTATCATCGGTATCTAGGCCCCTTCAAATGAATGAGACAACAGCAAATAGGCCATCCCCTGTCAGAGATT
TATGTTCTTCTTCCACGACAAATAATGACCCCTATGCAAAACCTCCAGACACACCTAGGCCTGTGATGACAGATCAATTTCCCAAATCCTTGGGCCTATC
CCGGTCTCCTGTAGTTTCAGAACAAACTGCAAAAGGCCCTATAGCAGCTGGAACCAGTGATCACTTTACTAAACCATCTCCTAGGGCAGATGTGTTTCAA
AGACAAAGGATACCTGACTCATATGCACGACCCTTGTTGACACCTGCACCTCTTGATAGTGGTCCTGGACCTTTTAAGACTCCAATGCAACCTCCTCCAT
CCTCTCAGGATCCTTATGGATCAGTGTCACAGGCATCAAGGCGATTGTCTGTTGACCCTTATGAAAGGCCTGCTTTGACACCAAGACCTATAGATAATTT
TTCTCATAATCAGTCAAATGATCCATATAGTCAGCCTCCCCTTACCCCACATCCAGCAGTGAATGAATCTTTTGCCCATCCTTCAAGGGCTTTTTCCCAG
CCTGGAACCATATCAAGGCCAACATCTCAGGACCCATACTCCCAACCCCCAGGAACTCCACGACCTGTTGTAGATTCTTATTCCCAATCTTCAGGAACAG
CTAGGTCCAATACAGACCCTTACTCTCAACCTCCTGGAACTCCCCGGCCTACTACTGTTGACCCATATAGTCAGCAGCCCCAAACCCCAAGACCATCTAC
ACAAACTGACTTGTTTGTTACACCTGTAACAAATCAGAGGCATTCTGATCCATATGCTCATCCTCCTGGAACACCAAGACCTGGAATTTCTGTCCCTTAC
TCTCAGCCACCAGCAACACCAAGGCCAAGGATTTCAGAGGGTTTTACTAGGTCCTCAATGACAAGACCAGTCCTCATGCCAAATCAGGATCCTTTCCTGC
AAGCAGCACAAAACCGAGGACCAGCTTTACCTGGCCCGTTGGTAAGGCCACCTGATACATGTTCCCAGACACCTAGGCCCCCTGGACCTGGTCTTTCAGA
CACATTTAGCCGTGTTTCCCCATCTGCTGCCCGTGATCCCTATGATCAGTCTCCAATGACTCCAAGATCTCAGTCTGACTCTTTTGGAACAAGTCAAACT
GCCCATGATGTTGCTGATCAGCCAAGGCCTGGATCAGAGGGGAGCTTCTGTGCATCTTCAAACTCTCCAATGCACTCCCAAGGCCAGCAGTTCTCTGGTG
TCTCCCAACTTCCTGGACCTGTGCCAACTTCAGGAGTAACTGATACACAGAATACTGTAAATATGGCCCAAGCAGATACAGAGAAATTGAGACAGCGGCA
GAAGTTACGTGAAATCATTCTCCAGCAGCAACAGCAGAAGAAGATTGCAGGTCGACAGGAGAAGGGGTCACAGGACTCACCCGCAGTGCCTCATCCAGGG
CCTCTTCAACACTGGCAACCAGAGAATGTTAACCAGGCTTTCACCAGACCCCCACCTCCCTATCCTGGGAACATTAGGTCTCCTGTTGCCCCTCCTTTAG
GACCTAGATATGCTGTTTTCCCAAAAGATCAGCGTGGACCCTATCCTCCTGATGTTGCTAGTATGGGGATGAGACCTCATGGATTTAGATTTGGATTTCC
AGGAGGTAGTCATGGTACCATGCCGAGTCAAGAGCGCTTCCTTGTGCCTCCTCAGCAAATACAGGGATCTGGAGTTTCTCCACAGCTAAGAAGATCAGTA
TCTGTAGATATGCCTAGGCCTTTAAATAACTCACAAATGAATAATCCAGTTGGACTTCCTCAGCATTTTTCACCACAGAGCTTGCCAGTTCAGCAGCACA
ACATACTGGGCCAAGCATATATTGAACTGAGACATAGGGCTCCTGACGGAAGGCAACGGCTGCCTTTCAGTGCTCCACCTGGCAGCGTTGTAGAGGCATC
TTCTAATCTGAGACATGGAAACTTCATTCCCCGGCCAGACTTTCCGGGCCCTAGACACACAGACCCCATGCGACGACCTCCCCAGGGTCTACCTAATCAG
CTACCTGTGCACCCAGATTTGGAACAAGTGCCACCATCTCAACAAGAGCAAGGTCATTCTGTCCATTCATCTTCTATGGTCATGAGGACTCTGAACCATC
CACTAGGTGGTGAATTTTCAGAAGCTCCTTTGTCAACATCTGTACCGTCTGAAACAACGTCTGATAATTTACAGATAACCACCCAGCCTTCTGATGGTCT
AGAGGAAAAACTTGATTCTGATGACCCTTCTGTGAAGGAACTGGATGTTAAAGACCTTGAGGGGGTTGAAGTCAAAGACTTAGATGATGAAGATCTTGAA
AACTTAAATTTAGATACAGAGGATGGCAAGGTAGTTGAATTGGATACTTTAGATAATTTGGAAACTAATGATCCCAACCTGGATGACCTCTTAAGGTCAG
GAGAGTTTGATATCATTGCATATACAGATCCAGAACTTGACATGGGAGATAAGAAAAGCATGTTTAATGAGGAACTAGACCTTCCAATTGATGATAAGTT
AGATAATCAGTGTGTATCTGTTGAACCAAAAAAAAAGGAACAAGAAAACAAAACTCTGGTTCTCTCTGATAAACATTCACCACAGAAAAAATCCACTGTT
ACCAATGAGGTAAAAACGGAAGTACTGTCTCCAAATTCTAAGGTGGAATCCAAATGTGAAACTGAAAAAAATGATGAGAATAAAGATAATGTTGACACTC
CTTGCTCACAGGCTTCTGCTCACTCAGACCTAAATGATGGAGAAAAGACTTCTTTGCATCCTTGTGATCCAGATCTATTTGAGAAAAGAACCAATCGAGA
AACTGCTGGCCCCAGTGCAAATGTCATTCAGGCATCCACTCAACTACCTGCTCAAGATGTAATAAACTCTTGTGGCATAACTGGATCAACTCCAGTTCTC
TCAAGTTTACTTGCTAATGAGAAATCTGATAATTCAGACATTAGGCCATCGGGGTCTCCACCACCACCAACTCTGCCGGCCTCCCCATCCAATCATGTGT
CAAGTTTGCCTCCTTTCATAGCACCGCCTGGCCGTGTTTTGGATAATGCCATGAATTCTAATGTGACAGTAGTCTCTAGGGTAAACCATGTTTTTTCTCA
GGGTGTGCAGGTAAACCCAGGGCTCATTCCAGGTCAATCAACAGTTAACCACAGTCTGGGGACAGGAAAACCTGCAACTCAAACTGGGCCTCAAACAAGT
CAGTCTGGTACCAGTAGCATGTCTGGACCCCAACAGCTAATGATTCCTCAAACATTAGCACAGCAGAATAGAGAGAGGCCCCTTCTTCTAGAAGAACAGC
CTCTACTTCTACAGGATCTTTTGGATCAAGAAAGGCAAGAACAGCAGCAGCAAAGACAGATGCAAGCCATGATTCGTCAGCGATCAGAACCGTTCTTCCC
TAATATTGATTTTGATGCAATTACAGATCCTATAATGAAAGCCAAAATGGTGGCCCTTAAAGGTATAAATAAAGTGATGGCACAAAACAATCTGGGCATG
CCACCAATGGTGATGAGCAGGTTCCCTTTTATGGGCCAGGTGGTAACTGGAACACAGAACAGTGAAGGACAGAACCTTGGACCACAGGCCATTCCTCAGG
ATGGCAGTATAACACATCAGATTTCTAGGCCTAATCCTCCAAATTTTGGTCCAGGCTTTGTCAATGATTCACAGCGTAAGCAGTATGAAGAGTGGCTCCA
GGAGACCCAACAGCTGCTTCAAATGCAGCAGAAGTATCTTGAAGAACAAATTGGTGCTCACAGAAAATCTAAGAAGGCCCTTTCAGCTAAACAACGTACT
GCCAAGAAAGCTGGGCGTGAATTTCCAGAGGAAGATGCAGAACAACTCAAGCATGTTACTGAACAGCAAAGCATGGTTCAGAAACAGCTAGAACAGATTC
GTAAACAACAGAAAGAACATGCTGAATTGATTGAAGATTATCGGATCAAACAGCAGCAGCAATGTGCAATGGCCCCACCTACCATGATGCCCAGTGTCCA
GCCCCAGCCACCCCTAATTCCAGGTGCCACTCCACCCACCATGAGCCAACCCACCTTTCCCATGGTGCCACAGCAGCTTCAGCACCAGCAGCACACAACA
GTTATTTCTGGCCATACTAGCCCTGTTAGAATGCCCAGTTTACCTGGATGGCAACCCAACAGTGCTCCTGCCCACCTGCCCCTCAATCCTCCTAGAATTC
AGCCCCCAATTGCCCAGTTACCAATAAAAACTTGTACACCAGCCCCAGGGACAGTCTCAAATGCAAATCCACAGAGTGGACCACCACCTCGGGTAGAATT
TGATGACAACAATCCCTTTAGTGAAAGTTTTCAAGAACGGGAACGTAAGGAACGTTTACGAGAACAGCAAGAGAGACAACGGATCCAACTCATGCAGGAG
GTAGATAGACAAAGAGCTTTGCAGCAGAGGATGGAAATGGAGCAGCATGGTATGGTGGGCTCTGAGATAAGTAGTAGTAGGACATCTGTGTCCCAGATTC
CCTTCTACAGTTCCGACTTACCTTGTGATTTTATGCAACCTCTAGGACCCCTTCAGCAGTCTCCACAACACCAACAGCAAATGGGGCAGGTTTTACAGCA
GCAGAATATACAACAAGGATCAATTAATTCACCCTCCACCCAAACTTTCATGCAGACTAATGAGCGAAGGCAGGTAGGCCCTCCTTCATTTGTTCCTGAT
TCACCATCAATCCCTGTTGGAAGCCCAAATTTTTCTTCTGTGAAGCAGGGACATGGAAATCTTTCTGGGACCAGCTTCCAGCAGTCCCCAGTGAGGCCTT
CTTTTACACCTGCTTTACCAGCAGCACCTCCAGTAGCTAATAGCAGTCTCCCATGTGGCCAAGATTCTACTATAACCCATGGACACAGTTATCCGGGATC
AACCCAATCGCTCATTCAGTTGTATTCTGATATAATCCCAGAGGAAAAAGGGAAAAAGAAAAGAACAAGAAAGAAGAAAAGAGATGATGATGCAGAATCC
ACCAAGGCTCCATCAACTCCCCATTCAGATATAACTGCCCCACCGACTCCAGGCATCTCAGAAACTACCTCTACTCCTGCAGTGAGCACACCCAGTGAGC
TTCCTCAACAAGCCGACCAAGAGTCGGTGGAACCAGTCGGCCCATCCACTCCCAATATGGCAGCAGGCCAGCTATGTACAGAATTAGAGAACAAACTGCC
CAATAGTGATTTCTCACAAGCAACTCCAAATCAACAGACGTATGCAAATTCAGAAGTAGACAAGCTCTCCATGGAAACCCCTGCCAAAACAGAAGAGATA
AAACTGGAAAAGGCTGAGACAGAGTCCTGCCCAGGCCAAGAGGAGCCTAAATTGGAGGAACAGAATGGTAGTAAGGTAGAAGGAAACGCTGTAGCCTGTC
CTGTCTCCTCAGCACAGAGTCCTCCCCATTCTGCTGGGGCCCCTGCTGCCAAAGGAGACTCAGGGAATGAACTTCTGAAACACTTGTTGAAAAATAAAAA
GTCATCTTCTCTTTTGAATCAAAAACCTGAGGGCAGTATTTGTTCAGAAGATGACTGTACAAAGGATAATAAACTAGTTGAGAAGCAGAACCCAGCTGAA
GGACTGCAAACTTTGGGGGCTCAAATGCAAGGTGGTTTTGGATGTGGCAACCAGTTGCCAAAAACAGATGGAGGAAGTGAAACCAAGAAACAGCGAAGCA
AACGGACTCAGAGGACGGGTGAGAAAGCAGCACCTCGCTCAAAGAAAAGGAAAAAGGACGAAGAGGAGAAACAAGCTATGTACTCTAGCACTGACACGTT
TACCCACTTGAAACAGGTGAGGCAGCTCTCTCTGCTCCCTCTAATGGAACCAATCATTGGAGTGAACTTTGCGCACTTTCTTCCTTATGGCAGTGGCCAA
TTTAATAGTGGGAATCGACTTCTAGGAACTTTTGGCAGTGCTACCCTGGAAGGGGTTTCGGACTACTATTCTCAGTTGATCTACAAGCAGAATAATTTAA
GTAATCCTCCAACACCCCCTGCCTCTCTTCCTCCTACACCACCTCCTATGGCTTGTCAGAAGATGGCCAATGGTTTTGCAACAACTGAAGAACTTGCTGG
AAAAGCCGGAGTGTTAGTGAGCCATGAAGTTACCAAAACTCTAGGACCTAAACCATTTCAGCTGCCCTTCAGACCCCAGGACGACTTGTTGGCCCGAGCT
CTTGCTCAGGGCCCCAAGACAGTTGATGTGCCAGCCTCCCTCCCAACACCACCTCATAACAATCAGGAAGAATTAAGGATACAGGATCACTGTGGTGATC
GAGATACTCCTGACAGTTTTGTTCCCTCATCCTCTCCTGAGAGTGTGGTTGGGGTAGAAGTGAGCAGGTATCCAGATCTGTCATTGGTCAAGGAGGAGCC
TCCAGAACCGGTGCCGTCCCCCATCATTCCAATTCTTCCTAGCACTGCTGGGAAAAGTTCAGAATCAAGAAGGAATGACATCAAAACTGAGCCAGGCACT
TTATATTTTGCGTCACCTTTTGGTCCTTCCCCAAATGGTCCCAGATCAGGTCTTATATCTGTAGCAATTACTCTGCATCCTACAGCTGCTGAGAACATTA
GCAGTGTTGTGGCTGCATTTTCCGACCTTCTTCACGTCCGAATCCCTAACAGCTATGAGGTTAGCAGTGCTCCAGATGTCCCATCCATGGGTTTGGTCAG
TAGCCACAGAATCAACCCGGGTTTGGAGTATCGACAGCATTTACTTCTCCGTGGGCCTCCGCCAGGATCTGCAAACCCTCCCAGATTAGTGAGCTCTTAC
CGGCTGAAGCAGCCTAATGTACCATTTCCTCCAACAAGCAATGGTCTTTCTGGATATAAGGATTCTAGTCATGGTATTGCAGAAAGCGCAGCACTCAGAC
CACAGTGGTGTTGTCATTGTAAAGTGGTTATTCTTGGAAGTGGTGTGCGGAAATCTTTCAAAGATCTGACCCTTTTGAACAAGGATTCCCGAGAAAGCAC
CAAGAGGGTAGAGAAGGACATTGTCTTCTGTAGTAATAACTGCTTTATTCTTTATTCATCAACTGCACAAGCGAAAAACTCAGAAAACAAGGAATCCATT
CCTTCATTGCCACAATCACCTATGAGAGAAACGCCTTCCAAAGCATTTCATCAGTACAGCAACAACATCTCCACTTTGGATGTGCACTGTCTCCCCCAGC
TCCCAGAGAAAGCTTCTCCCCCTGCCTCACCACCCATCGCCTTCCCTCCTGCTTTTGAAGCAGCCCAAGTCGAGGCCAAGCCAGATGAGCTGAAGGTGAC
AGTCAAGCTGAAGCCTCGGCTAAGAGCTGTCCATGGTGGGTTTGAAGATTGCAGGCCGCTCAATAAAAAATGGAGAGGAATGAAATGGAAGAAGTGGAGC
ATTCATATTGTAATCCCTAAGGGGACATTTAAACCACCTTGTGAGGATGAAATAGATGAATTTCTAAAGAAATTGGGCACTTCCCTTAAACCTGATCCTG
TGCCCAAAGACTATCGGAAATGTTGCTTTTGTCATGAAGAAGGTGATGGATTGACAGATGGACCAGCAAGGCTACTCAACCTTGACTTGGATCTGTGGGT
CCACTTGAACTGCGCTCTGTGGTCCACGGAGGTCTATGAGACTCAGGCTGGTGCCTTAATAAATGTGGAGCTAGCTCTGAGGAGAGGCCTACAAATGAAA
TGTGTCTTCTGTCACAAGACGGGTGCCACTAGTGGATGCCACAGATTTCGATGCACCAACATTTATCACTTCACTTGCGCCATTAAAGCACAATGCATGT
TTTTTAAGGACAAAACTATGCTTTGCCCCATGCACAAACCAAAGGGAATTCATGAGCAAGAATTAAGTTACTTTGCAGTCTTCAGGAGGGTCTATGTTCA
GCGTGATGAGGTGCGACAGATTGCTAGCATCGTGCAACGAGGAGAACGGGACCATACCTTTCGCGTGGGTAGCCTCATCTTCCACACAATTGGTCAGCTG
CTTCCACAGCAGATGCAAGCATTCCATTCTCCTAAAGCACTCTTCCCTGTGGGCTATGAAGCCAGCCGGCTGTACTGGAGCACTCGCTATGCCAATAGGC
GCTGCCGCTACCTGTGCTCCATTGAGGAGAAGGATGGGCGCCCAGTGTTTGTCATCAGGATTGTGGAACAAGGCCATGAAGACCTGGTTCTAAGTGACAT
CTCACCTAAAGGTGTCTGGGATAAGATTTTGGAGCCTGTGGCATGTGTGAGAAAAAAGTCTGAAATGCTCCAGCTTTTCCCAGCGTATTTAAAAGGAGAG
GATCTGTTTGGCCTGACCGTCTCTGCAGTGGCACGCATAGCGGAATCACTTCCTGGGGTTGAGGCATGTGAAAATTATACCTTCCGATACGGCCGAAATC
CTCTCATGGAACTTCCTCTTGCCGTTAACCCCACAGGTTGTGCCCGTTCTGAACCTAAAATGAGTGCCCATGTCAAGAGGCCTCACACCTTAAACAGCAC
CAGCACCTCAAAGTCATTTCAGAGCACAGTCACTGGAGAACTGAACGCACCTTATAGTAAACAGTTTGTTCACTCCAAGTCATCGCAGTACCGGAAGATG
AAAACTGAATGGAAATCCAATGTGTATCTGGCACGGTCTCGGATTCAGGGGCTGGGCCTGTATGCTGCTCGAGACATTGAGAAACACACCATGGTCATTG
AGTACATCGGGACTATCATTCGAAACGAAGTAGCCAACAGGAAAGAGAAGCTTTATGAGTCTCAGAACCGTGGTGTGTACATGTTCCGCATGGATAACGA
CCATGTGATTGACGCGACGCTCACAGGAGGGCCCGCAAGGTATATCAACCATTCGTGTGCACCTAATTGTGTGGCTGAAGTGGTGACTTTTGAGAGAGGA
CACAAAATTATCATCAGCTCCAGTCGGAGAATCCAGAAAGGAGAAGAGCTCTGCTATGACTATAAGTTTGACTTTGAAGATGACCAGCACAAGATTCCGT
GTCACTGTGGAGCTGTGAACTGCCGGAAGTGGATGAACTGAAATGCATTCCTTGCTAGCTCAGCGGGCGGCTTGTCCCTAGGAAGAGGCGATTCAACACA
CCATTGGAATTTTGCAGACAGAAAGAGATTTTTGTTTTCTGTTTTATGACTTTTTGAAAAAGCTTCTGGGAGTTCTGATTTCCTCAGTCCTTTAGGTTAA
AGCAGCGCCAGGAGGAAGCTGACAGAAGCAGCGTTCCTGAAGTGGCCGAGGTTAAACGGAATCACAGAATGGTCCAGCACTTTTGCTTTTTTTTCTTTTC
CTTTTCTTTTTTTTTTGTTTGTTTTTTGTTTTGTTTTTCCCTTGTGGGTGGGTTTCATTGTTTTGGTTTTCTAGTCTCACTAAGGAGAAACTTTTACTGG
GGCAAAGAGCCGATGGCTGCCCTGCCCCGGGCAGGGGCCTTCCTATGAATGTAAGACTGAAATCACCAGCGAGGGGGACAGAGAGTGCTGGCCACGGCCT
TATTAAAAAGGGGCAGGCCCTCTAACTTCAAAATGTTTTTAAATAAAGTAGACACCACTGAACAAGGAATGTACTGAAATGACTTCCTTAGGGATAGAGC
TAAGGGATAATAACTTGCACTAAATACATTTAAATACTTGATTCCATGAGTCAGTTTATTGTAGTTTTTGATTTCTGTAAAATAAGAGAAACTTTTGTAT
TTATTATTGAATAAGTGAATGAAGCTATTTTTAAATAAAGTTAGAAGAAAGCCAAGCTGCTGCTGTTACCTGCAGAACTAACAAACCCTGTTACTTTGTA
CAGATATGTAAATATTTTGAGAAAAAATACAGTATAAAAATAGTTATTGACCAAATGCTACCAGGCTCTGCAGCAGCTCGGGGGCTTATAAAATGTTCAT
AGGGATGTTACAATATAATTTTGTGTTATAAAATATGCCATTATAATTATGTAATAACCAAAATTTCAACCTAGAGTGTTGGGGGTTTTTTGGAAACCGC
AGTCTATTAGTACTCAATGGTTTTATACACCTTACTTCTGACAGAGCGGGGCGTATGCTACGACTACAACTTTTATAGCTGTTTTGGTAATTTAAACTAA
TTTTTTCATATTATATTGTTGCATCCCTACTTCTTCAGTCAGGTTTTTTTGTGCTTACAATTTGTGATAACTGTGAATAACTGCTTAAAAATACACCCAA
ATGGAGGCTGAATTTTTTCTTCAGCAAAAGTAGTTTTGATTAGAACTTTGTTTCAGCCACAGAGAATCATGTAAACGTAATAGGATCATGTAGCAGAAAC
TTAAATCTAACCCTTTAGCCTTCTATTTAACACAAAAATTTGAAAAAGTTAAAAAAAAAAAGGAGATGTGATTATGCTTACAGCTGCAGGACTCTGGCAA
TAGGGTTTTTGGAAGATGTAATTTTAAAATGTGTTTGTATGAACTGTTTGTTTACATTTCTTTAATAAAAAAAACACTGTTTTGTGTTTGCTTGTAGAAA
CTTAATCAGCATTTTGAACCAGGTTAGCTTTTTATTTTGTACTTAAAATTCTGGTACTGACACTTCACAGGCTAAGTATAAAATGAAGTTTTGTGTGCAC
AATTCAAGTGGACTGTAAACTGTTGGTATATTCAGTGATGCAGTTCTGAACTTGTATATGGCATGATGTATTTTTATCTTACAGAATAAATCAATTGTAT
ATATTTTTCTCTTGATAAATAGCTGTATGAAATTTGTTTCCTGAATATTTTTCTTCTCTTGTACAATATCCTGACATCCTACCAGTATTTGTCCTACCGG
GTTTTTGTTGTTTTCTGTTCTGTATAATAGTATCTAATGTTGGCAAAAATTGAATTTTTTGAAGTATACAGAGTGTTATGGGTTTTGGAATTTGTGGACA
CAGATTTAGAAGATCACCATTTACAAATAAAATATTTTACATCTATAA
- refseq_MLL3.F1 (forward primer)
- refseq_MLL3.R1 (reverse primer)
- Exon skipping and alternative donor or acceptor
Frame 0
KIP*LLALTFYVAEFYTSIFSTAIS*GAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVG
RGSGFPGKRRPRGAGLSGRGGRGRSKLKSGIGA
VVLPGVSTADISSNKDDEENSMHNTVVLFSSSD
KFTLNQDMCVVCGSFGQGAEGRLLACSQCGQCYH
PYCVSIKITKVVLSKGWRCLECTVCEACGKATD
PGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKC
KWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLS
SCPVCYRNYREEDLILQCRQCDRWMHAVCQNLN
TEEEVENVADIGFDCSMCRPYMPASNVPSSDCC
ESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMT
QLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQ
TPPDIQSEHSRDGEMDDSREGELMDCDGKSESS
PEREAVDDETKGVEGTDGVKKRKRKPYRPGIGGF
MVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCR
DDGWSEQLPDTLVDESVSVTESTEKIKKRYRKR
KNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDN
LSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAP
TKSGTHGPADDPLADISEVLNTDDDILGIISDD
LAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSE
EQLDGILSPELDKMVTDGAILGKLYKIPELGGK
DVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIH
NQDAFSRMPLMNGLIGSSPHLPHNSLPPGSGLGT
FSAIAQSSYPDARDKNSAFNPMASDPNNSWTSS
APTVEGENDTMSNAQRSTLKWEKEEALGEMATV
APVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKA
SSQERAPYVQKARDNRAALRINKVQMSNDSMKR
QQQQDSIDPSSRIDSELFKDPLKQRESEHEQEW
KFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQ
QQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGN
MSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQ
APPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPG
SSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN
SAAPVENCTPLSSVSRPLQMNETTANRPSPVRD
LCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLS
RSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQ
RQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPP
SSQDPYGSVSQASRRLSVDPYERPALTPRPIDNF
SHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQ
PGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGT
ARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST
QTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPY
SQPPATPRPRISEGFTRSSMTRPVLMPNQDPFL
QAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSD
TFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQT
AHDVADQPRPGSEGSFCASSNSPMHSQGQQFSG
VSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQ
KLREIILQQQQQKKIAGRQEKGSQDSPAVPHPG
PLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPL
GPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFP
GGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSV
SVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQH
NILGQAYIELRHRAPDGRQRLPFSAPPGSVVEAS
SNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQ
LPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNH
PLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGL
EEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLE
NLNLDTEDGKVVELDTLDNLETNDPNLDDLLRS
GEFDIIAYTDPELDMGDKKSMFNEELDLPIDDKL
DNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTV
TNEVKTEVLSPNSKVESKCETEKNDENKDNVDT
PCSQASAHSDLNDGEKTSLHPCDPDLFEKRTNRE
TAGPSANVIQASTQLPAQDVINSCGITGSTPVL
SSLLANEKSDNSDIRPSGSPPPPTLPASPSNHV
SSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQ
GVQVNPGLIPGQSTVNHSLGTGKPATQTGPQTS
QSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQ
PLLLQDLLDQERQEQQQQRQMQAMIRQRSEPFFP
NIDFDAITDPIMKAKMVALKGINKVMAQNNLGM
PPMVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQ
DGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQ
ETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRT
AKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQI
RKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQ
PQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTT
VISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRI
QPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEF
DDNNPFSESFQERERKERLREQQERQRIQLMQE
VDRQRALQQRMEMEQHGMVGSEISSSRTSVSQI
PFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQ
QNIQQGSINSPSTQTFMQTNERRQVGPPSFVPD
SPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRP
SFTPALPAAPPVANSSLPCGQDSTITHGHSYPGS
TQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAES
TKAPSTPHSDITAPPTPGISETTSTPAVSTPSE
LPQQADQESVEPVGPSTPNMAAGQLCTELENKLP
NSDFSQATPNQQTYANSEVDKLSMETPAKTEEI
KLEKAETESCPGQEEPKLEEQNGSKVEGNAVAC
PVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKK
SSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAE
GLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRS
KRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTF
THLKQVRQLSLLPLMEPIIGVNFAHFLPYGSGQ
FNSGNRLLGTFGSATLEGVSDYYSQLIYKQNNL
SNPPTPPASLPPTPPPMACQKMANGFATTEELAG
KAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARA
LAQGPKTVDVPASLPTPPHNNQEELRIQDHCGD
RDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEP
PEPVPSPIIPILPSTAGKSSESRRNDIKTEPGT
LYFASPFGPSPNGPRSGLISVAITLHPTAAENI
SSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVS
SHRINPGLEYRQHLLLRGPPPGSANPPRLVSSY
RLKQPNVPFPPTSNGLSGYKDSSHGIAESAALR
PQWCCHCKVVILGSGVRKSFKDLTLLNKDSREST
KRVEKDIVFCSNNCFILYSSTAQAKNSENKESI
PSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQ
LPEKASPPASPPIAFPPAFEAAQVEAKPDELKVT
VKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWS
IHIVIPKGTFKPPCEDEIDEFLKKLGTSLKPDP
VPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWV
HLNCALWSTEVYETQAGALINVELALRRGLQMK
CVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCM
FFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQ
RDEVRQIASIVQRGERDHTFRVGSLIFHTIGQL
LPQQMQAFHSPKALFPVGYEASRLYWSTRYANR
RCRYLCSIEEKDGRPVFVIRIVEQGHEDLVLSDI
SPKGVWDKILEPVACVRKKSEMLQLFPAYLKGE
DLFGLTVSAVARIAESLPGVEACENYTFRYGRN
PLMELPLAVNPTGCARSEPKMSAHVKRPHTLNST
STSKSFQSTVTGELNAPYSKQFVHSKSSQYRKM
KTEWKSNVYLARSRIQGLGLYAARDIEKHTMVI
EYIGTIIRNEVANRKEKLYESQNRGVYMFRMDND
HVIDATLTGGPARYINHSCAPNCVAEVVTFERG
HKIIISSSRRIQKGEELCYDYKFDFEDDQHKIP
CHCGAVNCRKWMN*NAFLASSAGGLSLGRGDSTH
HWNFADRKRFLFSVL*LFEKASGSSDFLSPLG*
SSARRKLTEAAFLKWPRLNGITEWSSTFAFFSF
PFLFFLFVFCFVFPLWVGFIVLVF*SH*GETFTG
AKSRWLPCPGQGPSYECKTEITSEGDRECWPRP
Y*KGAGPLTSKCF*IK*TPLNKECTEMTSLGIE
LRDNNLH*IHLNT*FHESVYCSF*FL*NKRNFCI
YY*ISE*SYF*IKLEESQAAAVTCRTNKPCYFV
QICKYFEKKYSIKIVIDQMLPGSAAARGLIKCS
*GCYNIILCYKICHYNYVITKIST*SVGGFLETA
VY*YSMVLYTLLLTERGVCYDYNFYSCFGNLN*
FFHIILLHPYFFSQVFLCLQFVITVNNCLKIHP
NGG*IFSSAKVVLIRTLFQPQRIM*T**DHVAET
*I*PFSLLFNTKI*KS*KKKGDVIMLTAAGLWQ
*GFWKM*F*NVFV*TVCLHFFNKKNTVLCLLVE
T*SAF*TRLAFYFVLKILVLTLHRLSIK*SFVCT
IQVDCKLLVYSVMQF*TCIWHDVFLSYRINQLY
IFFS**IAV*NLFPEYFSSLVQYPDILPVFVLP
GFCCFLFCIIVSNVGKN*IF*SIQSVMGFGICGH
RFRRSPFTNKIFYIY
Frame 1
KFLSCWL*PFMLLSFTHLFSQLPYPRGLGVPIIQ*AHLPGPQTFQKVGKFLNPGSFLAVPFGASKW
AVGLDFQESGDLEVQDCRGEVAEAGQS*KVESEL
LYYLGCLLQIFHQIRMMKKTLCTIQLCCFLAVT
SSL*IRICV*FVAVLAKEQKEDYLPVLSVVSVT
IHTVSVLRSLKWFLAKVGGVLSALCVRPVGRQLT
QEDSCCVMTVT*VITPTA*TLHCRQFPKEAGSA
NGVFGADTVEQHLQV*DVNGRTITHSALLVQAY
LPVQSAIETIEKKILFCNVDNVIDGCMQFVRT*I
LRKKWKM*QTLVLIVACADPICLRLMCLPQTAV
NLHL*HKLSQK*KS*THPRLIPRMVCV*LNQG*
LSYRASQLQFQEENGQNQN*N*RL*IRIAWPSFR
PLQTSNQSIQGMVKWMIVEKENLWIVMENQNLV
LSGKLWMMKLREWKEQMVSKREKGNHTDQVLVD
LWCGKEVELGKGKPKDL*SEKIPQALFPSSYLAE
MMAGVSSYQIL*LMNLFLLLKALKK*RRDTEKG
KISLKKLSLPIYKKLSLEKIF*IQVDKAR*V*I
ICQKMELSFYIKQT*TQVSWILP*IHYLVHPRLQ
QNLELTVLLMTH*LIFLKF*TQMMTFLE*FQMI
*QNQLIIQILVLSLMILPLCLSQMSIRVHDH*V
KNS*MGSSVLN*TKWSQMEQFLENYIKFQSLAEK
MLKTYLQLYLVLRTLSQLHCHSLPHQHSCCQYT
IRMLFHGCLS*MALLDPVLISHIILCHLEADWE
LSLQLHNPLILMPGIKIQPLIQWQVILTTLGHHQ
LPLWKEKMTQCRMPREARLSGRKRRLWVKWQLL
PQFSTPILISPT*RKNSLIGLLE*SKLPNCGEK
QAHKKEHHMCKKPEITELLYALIKYRCQMIP*KG
SNSKIALIPALVLIRSFLKIL*SKENQNMNRNG
NLDSKCVRKVSSKLKLKPHRNLNR*KMSSSSSN
NSNLVLSIFWCSLVQIHQVVGYRVP*HLSLAMEI
CLLHSHSIKNCLQNSHPVPLRLHLQMMCL*SHK
LHLLLQPHPGFPSRIVFLRLRLLSHPHRKCFHL
GPLTHDHHLQWIHMQKWLVPLDHLLWAIVFPEEI
LLHQWKTVHLYHRYLGPFK*MRQQQIGHPLSEI
YVLLPRQIMTPMQNLQTHLGL**QINFPNPWAY
PGLL*FQNKLQKAL*QLEPVITLLNHLLGQMCFK
DKGYLTHMHDPC*HLHLLIVVLDLLRLQCNLLH
PLRILMDQCHRHQGDCLLTLMKGLL*HQDL*II
FLIISQMIHIVSLPLPHIQQ*MNLLPILQGLFPS
LEPYQGQHLRTHTPNPQELHDLL*ILIPNLQEQ
LGPIQTLTLNLLELPGLLLLTHIVSSPKPQDHL
HKLTCLLHL*QIRGILIHMLILLEHQDLEFLSLT
LSHQQHQGQGFQRVLLGPQ*QDQSSCQIRILSC
KQHKTEDQLYLARW*GHLIHVPRHLGPLDLVFQ
THLAVFPHLLPVIPMISLQ*LQDLSLTLLEQVKL
PMMLLISQGLDQRGASVHLQTLQCTPKASSSLV
SPNFLDLCQLQE*LIHRIL*IWPKQIQRN*DSG
RSYVKSFSSSNSRRRLQVDRRRGHRTHPQCLIQG
LFNTGNQRMLTRLSPDPHLPILGTLGLLLPLL*
DLDMLFSQKISVDPILLMLLVWG*DLMDLDLDF
QEVVMVPCRVKSASLCLLSKYRDLEFLHS*EDQY
L*ICLGL*ITHK*IIQLDFLSIFHHRACQFSST
TYWAKHILN*DIGLLTEGNGCLSVLHLAAL*RH
LLI*DMETSFPGQTFRALDTQTPCDDLPRVYLIS
YLCTQIWNKCHHLNKSKVILSIHLLWS*GL*TI
H*VVNFQKLLCQHLYRLKQRLIIYR*PPSLLMV
*RKNLILMTLL*RNWMLKTLRGLKSKT*MMKILK
T*I*IQRMAR*LNWIL*IIWKLMIPTWMTS*GQ
ESLISLHIQIQNLTWEIRKACLMRN*TFQLMIS
*IISVYLLNQKKRNKKTKLWFSLINIHHRKNPLL
PMR*KRKYCLQILRWNPNVKLKKMMRIKIMLTL
LAHRLLLTQT*MMEKRLLCILVIQIYLRKEPIE
KLLAPVQMSFRHPLNYLLKM**TLVA*LDQLQFS
QVYLLMRNLIIQTLGHRGLHHHQLCRPPHPIMC
QVCLLS*HRLAVFWIMP*ILM*Q*SLG*TMFFL
RVCR*TQGSFQVNQQLTTVWGQENLQLKLGLKQV
SLVPVACLDPNS**FLKH*HSRIERGPFF*KNS
LYFYRIFWIKKGKNSSSKDRCKP*FVSDQNRSS
LILILMQLQIL**KPKWWPLKV*IK*WHKTIWAC
HQW**AGSLLWARW*LEHRTVKDRTLDHRPFLR
MAV*HIRFLGLILQILVQALSMIHSVSSMKSGS
RRPNSCFKCSRSILKNKLVLTENLRRPFQLNNVL
PRKLGVNFQRKMQNNSSMLLNSKAWFRNS*NRF
VNNRKNMLN*LKIIGSNSSSNVQWPHLP*CPVS
SPSHP*FQVPLHPP*ANPPFPWCHSSFSTSSTQQ
LFLAILALLECPVYLDGNPTVLLPTCPSILLEF
SPQLPSYQ*KLVHQPQGQSQMQIHRVDHHLG*N
LMTTIPLVKVFKNGNVRNVYENSKRDNGSNSCRR
*IDKELCSRGWKWSSMVWWALR*VVVGHLCPRF
PSTVPTYLVILCNL*DPFSSLHNTNSKWGRFYS
SRIYNKDQLIHPPPKLSCRLMSEGR*ALLHLFLI
HHQSLLEAQIFLL*SRDMEIFLGPASSSPQ*GL
LLHLLYQQHLQ*LIAVSHVAKILL*PMDTVIRD
QPNRSFSCILI*SQRKKGKRKEQERRKEMMMQNP
PRLHQLPIQI*LPHRLQASQKLPLLLQ*AHPVS
FLNKPTKSRWNQSAHPLPIWQQASYVQN*RTNC
PIVISHKQLQINRRMQIQK*TSSPWKPLPKQKR*
NWKRLRQSPAQAKRSLNWRNRMVVR*KETL*PV
LSPQHRVLPILLGPLLPKETQGMNF*NTC*KIK
SHLLF*IKNLRAVFVQKMTVQRIIN*LRSRTQLK
DCKLWGLKCKVVLDVATSCQKQMEEVKPRNSEA
NGLRGRVRKQHLAQRKGKRTKRRNKLCTLALTR
LPT*NR*GSSLCSL*WNQSLE*TLRTFFLMAVAN
LIVGIDF*ELLAVLPWKGFRTTILS*STSRII*
VILQHPLPLFLLHHLLWLVRRWPMVLQQLKNLL
EKPEC**AMKLPKL*DLNHFSCPSDPRTTCWPEL
LLRAPRQLMCQPPSQHHLITIRKN*GYRITVVI
EILLTVLFPHPLLRVWLG*K*AGIQICHWSRRS
LQNRCRPPSFQFFLALLGKVQNQEGMTSKLSQAL
YILRHLLVLPQMVPDQVLYL*QLLCILQLLRTL
AVLWLHFPTFFTSESLTAMRLAVLQMSHPWVWS
VATESTRVWSIDSIYFSVGLRQDLQTLPD**ALT
G*SSLMYHFLQQAMVFLDIRILVMVLQKAQHSD
HSGVVIVKWLFLEVVCGNLSKI*PF*TRIPEKA
PRG*RRTLSSVVITALFFIHQLHKRKTQKTRNPF
LHCHNHL*EKRLPKHFISTATTSPLWMCTVSPS
SQRKLLPLPHHPSPSLLLLKQPKSRPSQMS*R*
QSS*SLG*ELSMVGLKIAGRSIKNGEE*NGRSGA
FIL*SLRGHLNHLVRMK*MNF*RNWALPLNLIL
CPKTIGNVAFVMKKVMD*QMDQQGYSTLTWICG
ST*TALCGPRRSMRLRLVP**MWS*L*GEAYK*N
VSSVTRRVPLVDATDFDAPTFITSLAPLKHNAC
FLRTKLCFAPCTNQREFMSKN*VTLQSSGGSMF
SVMRCDRLLASCNEENGTIPFAWVASSSTQLVSC
FHSRCKHSILLKHSSLWAMKPAGCTGALAMPIG
AAATCAPLRRRMGAQCLSSGLWNKAMKTWF*VT
SHLKVSGIRFWSLWHV*EKSLKCSSFSQRI*KER
ICLA*PSLQWHA*RNHFLGLRHVKIIPSDTAEI
LSWNFLLPLTPQVVPVLNLK*VPMSRGLTP*TA
PAPQSHFRAQSLEN*THLIVNSLFTPSHRSTGR*
KLNGNPMCIWHGLGFRGWACMLLETLRNTPWSL
STSGLSFETK*PTGKRSFMSLRTVVCTCSAWIT
TM*LTRRSQEGPQGISTIRVHLIVWLKW*LLRED
TKLSSAPVGESRKEKSSAMTISLTLKMTSTRFR
VTVEL*TAGSG*TEMHSLLAQRAACP*EEAIQH
TIGILQTERDFCFLFYDFLKKLLGVLISSVL*VK
AAPGGS*QKQRS*SGRG*TESQNGPALLLFFLF
LFFFFCLFFVLFFPCGWVSLFWFSSLTKEKLLL
GQRADGCPAPGRGLPMNVRLKSPARGTESAGHGL
IKKGQAL*LQNVFK*SRHH*TRNVLK*LP*G*S
*GIITCTKYI*ILDSMSQFIVVFDFCKIRETFV
FIIE*VNEAIFK*S*KKAKLLLLPAELTNPVTLY
RYVNILRKNTV*K*LLTKCYQALQQLGGL*NVH
RDVTI*FCVIKYAIIIM**PKFQPRVLGVFWKP
QSISTQWFYTPYF*QSGAYATTTTFIAVLVI*TN
FFILYCCIPTSSVRFFCAYNL**L*ITA*KYTQ
MEAEFFLQQK*F*LELCFSHRESCKRNRIM*QK
LKSNPLAFYLTQKFEKVKKKKEM*LCLQLQDSGN
RVFGRCNFKMCLYELFVYISLIKKTLFCVCL*K
LNQHFEPG*LFILYLKFWY*HFTG*V*NEVLCA
QFKWTVNCWYIQ*CSSELVYGMMYFYLTE*INCI
YFSLDK*LYEICFLNIFLLLYNILTSYQYLSYR
VFVVFCSV**YLMLAKIEFFEVYRVLWVLEFVD
TDLEDHHLQIKYFTSI
Frame 2
NSLVAGFDLLCC*VLHIYFLNCHILGGLEYP*YSEPTFLVPRHFRRSGNF*TQAASWQCHLEHQSG
PWVWISRKAETSRCRTVGARWPRQVKAEKWNRS
CCITWGVYCRYFIK*G**RKLYAQYSCVVF*Q*Q
VHFESGYVCSLWQFWPRSRRKITCLFSVWSVLP
SILCQY*DH*SGS*QRLEVS*VHCV*GLWEGN*
PRKTPAV**L*HKLSHLLPRPSIADSSQRRLEVQ
MVCLVQTLWSNICRSKM*MAEQLHTVRSLCKLI
FLSSLLSKL*RRRSYSAM*TM**MDACSLSELK
Y*GRSGKCSRHWF*L*HVQTLYACV*CAFLRLL*
IFTCSTNCHKSKRARPTQDLYPGWCVFD*IRDD
SVTEPHSYSSKKKTVKTKIEIEDYKSE*RGRPS
DPSRHPIRAFKGW*NG**SRRRTYGL*WKIRI*S
*AGSCG**N*GSGRNRWCQKEKKETIQTRYWWI
YGAAKKSNWARENQKICDQKRFLRLYFRAVTLQ
R*WLE*AVTRYFS**ICFCY*KH*KNKEEIPKKE
K*A*RNFPCLFTRSFLWKRSSRYK*TKQDKFR*
SVRRWSSAFI*NKHEHRFLGSFLRSTT*FILGS
NKIWNSRSC**PIS*YF*SFKHR**HSWNNFR*S
SKIS*SFRYWSCH**SFLFASAKCQSEFTTIK*
RTARWDPQS*TRQNGHRWSNSWKII*NSRAWRK
RC*RLIYSCT*SCEHSANSIATASPTNTAVANTQ
SGCFFTDASHEWPYWIQSSSPT*FFATWKRTGN
FLCNCTILLS*CQG*KFSL*SNGK*S*QLLDII
SSHCGRRK*HNVECPEKHA*VGERGGSG*NGNCC
PSSLHQY*FPQLKGRIP*LDY*SEANCQIVEKS
KLTRKSTICAKSQR*QSCFTH**STDVK*FHEK
AATAR*H*SQLSY*FGAF*RSFKAKRIRT*TGME
I*TANASEK*AAS*N*SHTET*TGEK*AAAAAT
TAIWFSASSGAVWFRYTK*WDTESLDTSAWQWK
YVSCTVIP*RTVYKTATQYPYVYIFR*CVCKATS
STSSSSPIPDSHPG*SFSGSDFSATLTASVFTW
VL*LTTTISNGSICKNGWYPSTTSCGP*FFQKK
FCCTSGKLYTFIIGI*APSNE*DNSK*AIPCQRF
MFFFHDK**PLCKTSRHT*ACDDRSISQILGPI
PVSCSFRTNCKRPYSSWNQ*SLY*TIS*GRCVS
KTKDT*LICTTLVDTCTS**WSWTF*DSNATSSI
LSGSLWISVTGIKAIVC*PL*KACFDTKTYR*F
FS*SVK*SI*SASPYPTSSSE*IFCPSFKGFFP
AWNHIKANISGPILPTPRNSTTCCRFLFPIFRNS
*VQYRPLLSTSWNSPAYYC*PI*SAAPNPKTIY
TN*LVCYTCNKSEAF*SICSSSWNTKTWNFCPL
LSATSNTKAKDFRGFY*VLNDKTSPHAKSGSFPA
SSTKPRTSFTWPVGKAT*YMFPDT*APWTWSFR
HI*PCFPICCP*SL*SVSNDSKISV*LFWNKSN
CP*CC*SAKAWIRGELLCIFKLSNALPRPAVLWC
LPTSWTCANFRSN*YTEYCKYGPSRYREIETAA
EVT*NHSPAATAEEDCRSTGEGVTGLTRSASSR
ASSTLATREC*PGFHQTPTSLSWEH*VSCCPSFR
T*ICCFPKRSAWTLSS*CC*YGDETSWI*IWIS
RR*SWYHAESRALPCASSANTGIWSFSTAKKIS
ICRYA*AFK*LTNE*SSWTSSAFFTTELASSAAQ
HTGPSIY*TET*GS*RKATAAFQCSTWQRCRGI
F*SETWKLHSPARLSGP*THRPHATTSPGST*S
ATCAPRFGTSATISTRARSFCPFIFYGHEDSEPS
TRW*IFRSSFVNICTV*NNV**FTDNHPAF*WS
RGKT*F**PFCEGTGC*RP*GG*SQRLR**RS*
KLKFRYRGWQGS*IGYFR*FGN**SQPG*PLKVR
RV*YHCIYRSRT*HGR*EKHV**GTRPSN***V
R*SVCIC*TKKKGTRKQNSGSL**TFTTEKIHC
YQ*GKNGSTVSKF*GGIQM*N*KK**E*R*C*HS
LLTGFCSLRPK*WRKDFFASL*SRSI*EKNQSR
NCWPQCKCHSGIHSTTCSRCNKLLWHNWINSSS
LKFTC**EI**FRH*AIGVSTTTNSAGLPIQSCV
KFASFHSTAWPCFG*CHEF*CDSSL*GKPCFFS
GCAGKPRAHSRSINS*PQSGDRKTCNSNWASNK
SVWYQ*HVWTPTANDSSNISTAE*REAPSSRRTA
STSTGSFGSRKARTAAAKTDASHDSSAIRTVLP
*Y*F*CNYRSYNESQNGGP*RYK*SDGTKQSGH
ATNGDEQVPFYGPGGNWNTEQ*RTEPWTTGHSSG
WQYNTSDF*A*SSKFWSRLCQ*FTA*AV*RVAP
GDPTAASNAAEVS*RTNWCSQKI*EGPFS*TTY
CQESWA*ISRGRCRTTQACY*TAKHGSETARTDS
*TTERTC*ID*RLSDQTAAAMCNGPTYHDAQCP
APATPNSRCHSTHHEPTHLSHGATAASAPAAHN
SYFWPY*PC*NAQFTWMATQQCSCPPAPQSS*NS
APNCPVTNKNLYTSPRDSLKCKSTEWTTTSGRI
**QQSL**KFSRTGT*GTFTRTARETTDPTHAG
GR*TKSFAAEDGNGAAWYGGL*DK***DICVPDS
LLQFRLTL*FYATSRTPSAVSTTPTANGAGFTA
AEYTTRIN*FTLHPNFHAD**AKAGRPSFICS*
FTINPCWKPKFFFCEAGTWKSFWDQLPAVPSEAF
FYTCFTSSTSSS**QSPMWPRFYYNPWTQLSGI
NPIAHSVVF*YNPRGKREKEKNKKEEKR**CRI
HQGSINSPFRYNCPTDSRHLRNYLYSCSEHTQ*A
SSTSRPRVGGTSRPIHSQYGSRPAMYRIREQTA
Q**FLTSNSKSTDVCKFRSRQALHGNPCQNRRD
KTGKG*DRVLPRPRGA*IGGTEW**GRRKRCSLS
CLLSTESSPFCWGPCCQRRLRE*TSETLVEK*K
VIFSFESKT*GQYLFRR*LYKG**TS*EAEPS*
RTANFGGSNARWFWMWQPVAKNRWRK*NQETAKQ
TDSEDG*ESSTSLKEKEKGRRGETSYVL*H*HV
YPLETGEAALSAPSNGTNHWSELCALSSLWQWP
I**WESTSRNFWQCYPGRGFGLLFSVDLQAE*FK
*SSNTPCLSSSYTTSYGLSEDGQWFCNN*RTCW
KSRSVSEP*SYQNSRT*TISAALQTPGRLVGPS
SCSGPQDS*CASLPPNTTS*QSGRIKDTGSLW*S
RYS*QFCSLILS*ECGWGRSEQVSRSVIGQGGA
SRTGAVPHHSNSS*HCWEKFRIKKE*HQN*ARH
FIFCVTFWSFPKWSQIRSYICSNYSASYSC*EH*
QCCGCIFRPSSRPNP*QL*G*QCSRCPIHGFGQ
*PQNQPGFGVSTAFTSPWASARICKPSQISELL
PAEAA*CTISSNKQWSFWI*GF*SWYCRKRSTQT
TVVLSL*SGYSWKWCAEIFQRSDPFEQGFPRKH
QEGREGHCLL***LLYSLFINCTSEKLRKQGIH
SFIATITYERNAFQSISSVQQQHLHFGCALSPPA
PRESFSPCLTTHRLPSCF*SSPSRGQAR*AEGD
SQAEASAKSCPWWV*RLQAAQ*KMERNEMEEVE
HSYCNP*GDI*TTL*G*NR*ISKEIGHFP*T*SC
AQRLSEMLLLS*RR*WIDRWTSKATQP*LGSVG
PLELRSVVHGGL*DSGWCLNKCGASSEERPTNE
MCLLSQDGCH*WMPQISMHQHLSLHLRH*STMHV
F*GQNYALPHAQTKGNS*ARIKLLCSLQEGLCS
A**GATDC*HRATRRTGPYLSRG*PHLPHNWSA
ASTADASIPFS*STLPCGL*SQPAVLEHSLCQ*A
LPLPVLH*GEGWAPSVCHQDCGTRP*RPGSK*H
LT*RCLG*DFGACGMCEKKV*NAPAFPSVFKRR
GSVWPDRLCSGTHSGITSWG*GM*KLYLPIRPKS
SHGTSSCR*PHRLCPF*T*NECPCQEASHLKQH
QHLKVISEHSHWRTERTL**TVCSLQVIAVPED
EN*MEIQCVSGTVSDSGAGPVCCSRH*ETHHGH*
VHRDYHSKRSSQQEREAL*VSEPWCVHVPHG*R
PCD*RDAHRRARKVYQPFVCT*LCG*SGDF*ER
TQNYHQLQSENPERRRALL*L*V*L*R*PAQDSV
SLWSCELPEVDELKCIPC*LSGRLVPRKRRFNT
PLEFCRQKEIFVFCFMTF*KSFWEF*FPQSFRL
KQRQEEADRSSVPEVAEVKRNHRMVQHFCFFFFS
FSFFFVCFLFCFSLVGGFHCFGFLVSLRRNFYW
GKEPMAALPRAGAFL*M*D*NHQRGGQRVLATA
LLKRGRPSNFKMFLNKVDTTEQGMY*NDFLRDRA
KG**LALNTFKYLIP*VSLL*FLISVK*EKLLY
LLLNK*MKLFLNKVRRKPSCCCYLQN*QTLLLC
TDM*IF*EKIQYKNSY*PNATRLCSSSGAYKMFI
GMLQYNFVL*NMPL*LCNNQNFNLECWGFFGNR
SLLVLNGFIHLTSDRAGRMLRLQLL*LFW*FKL
IFSYYIVASLLLQSGFFVLTICDNCE*LLKNTPK
WRLNFFFSKSSFD*NFVSATENHVNVIGSCSRN
LNLTL*PSI*HKNLKKLKKKRRCDYAYSCRTLA
IGFLEDVILKCVCMNCLFTFL**KKHCFVFACRN
LISILNQVSFLFCT*NSGTDTSQAKYKMKFCVH
NSSGL*TVGIFSDAVLNLYMA*CIFILQNKSIV
YIFLLINSCMKFVS*IFFFSCTIS*HPTSICPTG
FLLFSVLYNSI*CWQKLNFLKYTECYGFWNLWT
QI*KITIYK*NILHL*
Copyright ©2008,2017, all rights reserved. 