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Sequences

Sequence NM_024507

GTAGAGGCTGAGGCACCGCCCAGAGCTCGCTGAGACAGAGACTGAGAACGCCCCCGGCCAGATTCCCCCCGGAGAGACCCGGGTAGGGACAGGGACAGAG AGACGCCTCTAGGGGCAGAGGCCCTGGGAGGCAAAGACCCCCAGGAGAGATTTACCCACCCCAGACGGAAAGCGCGGCTCAGAGTCGGACGAGGGGAGAC TGTCAGAGGACAACGCCCCCTAGGTCTCCTGGGAGACCCCGAAGCGACCCCGGGGGCAGCCCGGGCCGTGTCCGGGCGAGGGTGACCTATCCTTGGTTGA GAGCGATGGGGACACAAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGCAGCCGCGTGGGGCCTCGGCTGGGAGCCTGCACAGTCCAGG CCTGTCCGAATGCTTCCAGGTGAATGGGGCTGACTACCGCGGCCACCAGAACCGCACTGGCCCGCGCGGGGCGGGCCGCCCGTGCCTCTTCTGGGACCAG ACGCAGCAACACAGCTACAGCAGCGCCAGCGACCCCCACGGCCGCTGGGGGCTGGGCGCGCACAACTTCTGCCGTAACCCAGACGGTGACGTGCAGCCGT GGTGCTACGTGGCTGAGACAGAGGAGGGCATCTACTGGCGCTACTGCGACATCCCCTCCTGTCACATGCCAGGCTACCTGGGATGCTTTGTGGACTCAGG GGCACCCCCAGCCCTCAGCGGCCCCAGCGGCACCTCCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCATGAAGGGGTACCAGCTGGCGGGC GTGGAGGCCGGTTACGCCTGCTTCTGTGGCTCTGAAAGCGACCTGGCCCGGGGACGCCTGGCCCCCGCCACCGACTGTGACCAGATCTGTTTCGGCCACC CTGGACAGCTGTGTGGCGGCGATGGGCGGCTGGGCGTCTATGAAGTGTCGGTGGGCTCCTGCCAGGGGAACTGGACAGCGCCTCAGGGCGTCATCTACTC CCCGGACTTCCCGGACGAGTACGGGCCGGACCGGAACTGCAGCTGGGCCCTGGGCCCGCCAGGCGCCGCGCTGGAGCTCACCTTCCGCCTCTTCGAGCTG GCCGACCCGCGCGACCGGCTGGAGCTGCGCGACGCGGCTTCGGGCAGCCTGCTCCGCGCCTTCGATGGCGCCCGCCCACCGCCGTCCGGGCCGCTGCGCC TGGGCACTGCCGCGCTGCTGCTCACCTTCCGAAGCGACGCGCGCGGCCACGCGCAAGGCTTCGCGCTCACCTACCGCGGGCTGCAGGACGCCGCTGAGGA CCCAGAGGCCCCCGAGGGCTCGGCCCAGACCCCCGCGGCGCCCCTCGACGGGGCCAACGTGAGCTGCAGCCCCAGGCCTGGGGCTCCGCCGGCCGCGATT GGGGGAGCTGTCTGCTGGCTCCGGGAAAAGGGCCCCCGGCGCTGGGGGCTTCCAGGGGCCCCAGGAGAAGCTGGGCTGTGTGGTACCAACAGCCCCGAGG GGTGGCCTTGCCCTGCTCCCCCGGGGACCCCCAGGCTGAGGGTTCTGCCGCGGGCTACCGGCCTCTGAGTGCCTCCAGCCAGAGCTCCCTGCGCTCGCTC ATCTCCGCTCTCTGACTCTGGGCCCCGAGGGTCCGCTGGGCCCGCCGCCGGCGAGATGGACACCTGAGATGCTGTGCTGCGCCCTGCCTCGGCCTTGCGC CTGTGTAGGGGCAGCTCGGCCTCTGGTCGCCTTGGGGAGACCAAAAGTCGGACAGGAAACATCTGGTGCTATTATCTGGGACTTGGCCTGACCGTGGGGG TCCAGATGGTCCAGGCCCTCTCCATGGACCTGTATGTGGGGGTGGTCTCTGGTTTCGGAGGTCTTTGAACCCCTCTGGGGGTGGTCCTGGACTGCCGTCC TCAGTGAGAGGTCACAGGTCAGCAAAAACAGTCAAAAAACCCCCACAGATTTTGAATAAAGGATCTACTTTGGTA

refseq_KREMEN2.F1 (forward primer)
refseq_KREMEN2.R1 (reverse primer)
Single exon skipping

Frame 0

VEAEAPPRAR*DRD*ERPRPDSPRRDPGRDRDR ETPLGAEALGGKDPQERFTHPRRKARLRVGRGET VRGQRPLGLLGDPEATPGAARAVSGRG*PILG* ERWGHKPCRASSFSSSSRCCSRVGPRLGACTVQ ACPNASR*MGLTTAATRTALARAGRAARASSGTR RSNTATAAPATPTAAGGWARTTSAVTQTVTCSR GATWLRQRRASTGATATSPPVTCQATWDALWTQ GHPQPSAAPAAPPRSSRSRCAYASAA*RGTSWRA WRPVTPASVALKATWPGDAWPPPPTVTRSVSAT LDSCVAAMGGWASMKCRWAPARGTGQRLRASST PRTSRTSTGRTGTAAGPWARQAPRWSSPSASSSW PTRATGWSCATRLRAACSAPSMAPAHRRPGRCA WALPRCCSPSEATRAATRKASRSPTAGCRTPLR TQRPPRARPRPPRRPSTGPT*AAAPGLGLRRPRL GELSAGSGKRAPGAGGFQGPQEKLGCVVPTAPR GGLALLPRGPPG*GFCRGLPASECLQPELPALA HLRSLTLGPEGPLGPPPARWTPEMLCCALPRPCA CVGAARPLVALGRPKVGQETSGAIIWDLA*PWG SRWSRPSPWTCMWGWSLVSEVFEPLWGWSWTAV LSERSQVSKNSQKTPTDFE*RIYFG

Frame 1

*RLRHRPELAETETENAPGQIPPGETRVGTGTE RRL*GQRPWEAKTPRRDLPTPDGKRGSESDEGR LSEDNAP*VSWETPKRPRGQPGPCPGEGDLSLVE SDGDTSPAGLPLSPLPPAAAAAWGLGWEPAQSR PVRMLPGEWG*LPRPPEPHWPARGGPPVPLLGP DAATQLQQRQRPPRPLGAGRAQLLP*PRR*RAAV VLRG*DRGGHLLALLRHPLLSHARLPGMLCGLR GTPSPQRPQRHLHEAHGPGVPTLLPHEGVPAGG RGGRLRLLLWL*KRPGPGTPGPRHRL*PDLFRPP WTAVWRRWAAGRL*SVGGLLPGELDSASGRHLL PGLPGRVRAGPELQLGPGPARRRAGAHLPPLRA GRPARPAGAARRGFGQPAPRLRWRPPTAVRAAAP GHCRAAAHLPKRRARPRARLRAHLPRAAGRR*G PRGPRGLGPDPRGAPRRGQRELQPQAWGSAGRD WGSCLLAPGKGPPALGASRGPRRSWAVWYQQPRG VALPCSPGDPQAEGSAAGYRPLSASSQSSLRSL ISAL*LWAPRVRWARRRRDGHLRCCAAPCLGLA PV*GQLGLWSPWGDQKSDRKHLVLLSGTWPDRGG PDGPGPLHGPVCGGGLWFRRSLNPSGGGPGLPS SVRGHRSAKTVKKPPQILNKGSTLV

Frame 2

RG*GTAQSSLRQRLRTPPARFPPERPG*GQGQR DASRGRGPGRQRPPGEIYPPQTESAAQSRTRGD CQRTTPPRSPGRPRSDPGGSPGRVRARVTYPWL RAMGTQALQGFLFLLFLPLLQPRGASAGSLHSPG LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQ TQQHSYSSASDPHGRWGLGAHNFCRNPDGDVQP WCYVAETEEGIYWRYCDIPSCHMPGYLGCFVDSG APPALSGPSGTSTKLTVQVCLRFCRMKGYQLAG VEAGYACFCGSESDLARGRLAPATDCDQICFGH PGQLCGGDGRLGVYEVSVGSCQGNWTAPQGVIYS PDFPDEYGPDRNCSWALGPPGAALELTFRLFEL ADPRDRLELRDAASGSLLRAFDGARPPPSGPLR LGTAALLLTFRSDARGHAQGFALTYRGLQDAAED PEAPEGSAQTPAAPLDGANVSCSPRPGAPPAAI GGAVCWLREKGPRRWGLPGAPGEAGLCGTNSPE GWPCPAPPGTPRLRVLPRATGL*VPPARAPCARS SPLSDSGPRGSAGPAAGEMDT*DAVLRPASALR LCRGSSASGRLGETKSRTGNIWCYYLGLGLTVG VQMVQALSMDLYVGVVSGFGGL*TPLGVVLDCRP Q*EVTGQQKQSKNPHRF*IKDLLW

Sequence NM_172229

GTAGAGGCTGAGGCACCGCCCAGAGCTCGCTGAGACAGAGACTGAGAACGCCCCCGGCCAGATTCCCCCCGGAGAGACCCGGGTAGGGACAGGGACAGAG AGACGCCTCTAGGGGCAGAGGCCCTGGGAGGCAAAGACCCCCAGGAGAGATTTACCCACCCCAGACGGAAAGCGCGGCTCAGAGTCGGACGAGGGGAGAC TGTCAGAGGACAACGCCCCCTAGGTCTCCTGGGAGACCCCGAAGCGACCCCGGGGGCAGCCCGGGCCGTGTCCGGGCGAGGGTGACCTATCCTTGGTTGA GAGCGATGGGGACACAAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGCAGCCGCGTGGGGCCTCGGCTGGGAGCCTGCACAGTCCAGG CCTGTCCGAATGCTTCCAGGTGAATGGGGCTGACTACCGCGGCCACCAGAACCGCACTGGCCCGCGCGGGGCGGGCCGCCCGTGCCTCTTCTGGGACCAG ACGCAGCAACACAGCTACAGCAGCGCCAGCGACCCCCACGGCCGCTGGGGGCTGGGCGCGCACAACTTCTGCCGTAACCCAGACGGTGACGTGCAGCCGT GGTGCTACGTGGCTGAGACAGAGGAGGGCATCTACTGGCGCTACTGCGACATCCCCTCCTGTCACATGCCAGGCTACCTGGGATGCTTTGTGGACTCAGG GGCACCCCCAGCCCTCAGCGGCCCCAGCGGCACCTCCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCATGAAGGGGTACCAGCTGGCGGGC GTGGAGGCCGGTTACGCCTGCTTCTGTGGCTCTGAAAGCGACCTGGCCCGGGGACGCCTGGCCCCCGCCACCGACTGTGACCAGATCTGTTTCGGCCACC CTGGACAGCTGTGTGGCGGCGATGGGCGGCTGGGCGTCTATGAAGTGTCGGTGGGCTCCTGCCAGGGGAACTGGACAGCGCCTCAGGGCGTCATCTACTC CCCGGACTTCCCGGACGAGTACGGGCCGGACCGGAACTGCAGCTGGGCCCTGGGCCCGCCAGGCGCCGCGCTGGAGCTCACCTTCCGCCTCTTCGAGCTG GCCGACCCGCGCGACCGGCTGGAGCTGCGCGACGCGGCTTCGGGCAGCCTGCTCCGCGCCTTCGATGGCGCCCGCCCACCGCCGTCCGGGCCGCTGCGCC TGGGCACTGCCGCGCTGCTGCTCACCTTCCGAAGCGACGCGCGCGGCCACGCGCAAGGCTTCGCGCTCACCTACCGCGGGCTGCAGGACGCCGCTGAGGA CCCAGAGGCCCCCGAGGGCTCGGCCCAGACCCCCGCGGCGCCCCTCGACGGGGCCAACGTGAGCTGCAGCCCCAGGCCTGGGGCTCCGCCGGCCGCGATT GGGGCCCGGGTCTTCTCGACGGTGACGGCTGTCTCGGTGCTGCTGCTGCTGCTCCTGGGGCTGCTGCGTCCGCTGCGCCGACGGAGCTGTCTGCTGGCTC CGGGAAAAGGGCCCCCGGCGCTGGGGGCTTCCAGGGGCCCCAGGAGAAGCTGGGCTGTGTGGTACCAACAGCCCCGAGGGGTGGCCTTGCCCTGCTCCCC CGGGGACCCCCAGGCTGAGGGTTCTGCCGCGGGCTACCGGCCTCTGAGTGCCTCCAGCCAGAGCTCCCTGCGCTCGCTCATCTCCGCTCTCTGACTCTGG GCCCCGAGGGTCCGCTGGGCCCGCCGCCGGCGAGATGGACACCTGAGATGCTGTGCTGCGCCCTGCCTCGGCCTTGCGCCTGTGTAGGGGCAGCTCGGCC TCTGGTCGCCTTGGGGAGACCAAAAGTCGGACAGGAAACATCTGGTGCTATTATCTGGGACTTGGCCTGACCGTGGGGGTCCAGATGGTCCAGGCCCTCT CCATGGACCTGTATGTGGGGGTGGTCTCTGGTTTCGGAGGTCTTTGAACCCCTCTGGGGGTGGTCCTGGACTGCCGTCCTCAGTGAGAGGTCACAGGTCA GCAAAAACAGTCAAAAAACCCCCACAGATTTTGAATAAAGGATCTACTTTGGTA

refseq_KREMEN2.F1 (forward primer)
refseq_KREMEN2.R1 (reverse primer)
Single exon skipping

Frame 0

VEAEAPPRAR*DRD*ERPRPDSPRRDPGRDRDR ETPLGAEALGGKDPQERFTHPRRKARLRVGRGET VRGQRPLGLLGDPEATPGAARAVSGRG*PILG* ERWGHKPCRASSFSSSSRCCSRVGPRLGACTVQ ACPNASR*MGLTTAATRTALARAGRAARASSGTR RSNTATAAPATPTAAGGWARTTSAVTQTVTCSR GATWLRQRRASTGATATSPPVTCQATWDALWTQ GHPQPSAAPAAPPRSSRSRCAYASAA*RGTSWRA WRPVTPASVALKATWPGDAWPPPPTVTRSVSAT LDSCVAAMGGWASMKCRWAPARGTGQRLRASST PRTSRTSTGRTGTAAGPWARQAPRWSSPSASSSW PTRATGWSCATRLRAACSAPSMAPAHRRPGRCA WALPRCCSPSEATRAATRKASRSPTAGCRTPLR TQRPPRARPRPPRRPSTGPT*AAAPGLGLRRPRL GPGSSRR*RLSRCCCCCSWGCCVRCADGAVCWL REKGPRRWGLPGAPGEAGLCGTNSPEGWPCPAP PGTPRLRVLPRATGL*VPPARAPCARSSPLSDSG PRGSAGPAAGEMDT*DAVLRPASALRLCRGSSA SGRLGETKSRTGNIWCYYLGLGLTVGVQMVQAL SMDLYVGVVSGFGGL*TPLGVVLDCRPQ*EVTGQ QKQSKNPHRF*IKDLLW

Frame 1

*RLRHRPELAETETENAPGQIPPGETRVGTGTE RRL*GQRPWEAKTPRRDLPTPDGKRGSESDEGR LSEDNAP*VSWETPKRPRGQPGPCPGEGDLSLVE SDGDTSPAGLPLSPLPPAAAAAWGLGWEPAQSR PVRMLPGEWG*LPRPPEPHWPARGGPPVPLLGP DAATQLQQRQRPPRPLGAGRAQLLP*PRR*RAAV VLRG*DRGGHLLALLRHPLLSHARLPGMLCGLR GTPSPQRPQRHLHEAHGPGVPTLLPHEGVPAGG RGGRLRLLLWL*KRPGPGTPGPRHRL*PDLFRPP WTAVWRRWAAGRL*SVGGLLPGELDSASGRHLL PGLPGRVRAGPELQLGPGPARRRAGAHLPPLRA GRPARPAGAARRGFGQPAPRLRWRPPTAVRAAAP GHCRAAAHLPKRRARPRARLRAHLPRAAGRR*G PRGPRGLGPDPRGAPRRGQRELQPQAWGSAGRD WGPGLLDGDGCLGAAAAAPGAAASAAPTELSAGS GKRAPGAGGFQGPQEKLGCVVPTAPRGGLALLP RGPPG*GFCRGLPASECLQPELPALAHLRSLTL GPEGPLGPPPARWTPEMLCCALPRPCACVGAARP LVALGRPKVGQETSGAIIWDLA*PWGSRWSRPS PWTCMWGWSLVSEVFEPLWGWSWTAVLSERSQV SKNSQKTPTDFE*RIYFG

Frame 2

RG*GTAQSSLRQRLRTPPARFPPERPG*GQGQR DASRGRGPGRQRPPGEIYPPQTESAAQSRTRGD CQRTTPPRSPGRPRSDPGGSPGRVRARVTYPWL RAMGTQALQGFLFLLFLPLLQPRGASAGSLHSPG LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQ TQQHSYSSASDPHGRWGLGAHNFCRNPDGDVQP WCYVAETEEGIYWRYCDIPSCHMPGYLGCFVDSG APPALSGPSGTSTKLTVQVCLRFCRMKGYQLAG VEAGYACFCGSESDLARGRLAPATDCDQICFGH PGQLCGGDGRLGVYEVSVGSCQGNWTAPQGVIYS PDFPDEYGPDRNCSWALGPPGAALELTFRLFEL ADPRDRLELRDAASGSLLRAFDGARPPPSGPLR LGTAALLLTFRSDARGHAQGFALTYRGLQDAAED PEAPEGSAQTPAAPLDGANVSCSPRPGAPPAAI GARVFSTVTAVSVLLLLLLGLLRPLRRRSCLLA PGKGPPALGASRGPRRSWAVWYQQPRGVALPCSP GDPQAEGSAAGYRPLSASSQSSLRSLISAL*LW APRVRWARRRRDGHLRCCAAPCLGLAPV*GQLG LWSPWGDQKSDRKHLVLLSGTWPDRGGPDGPGPL HGPVCGGGLWFRRSLNPSGGGPGLPSSVRGHRS AKTVKKPPQILNKGSTLV